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G |
Abcc9 |
ATP binding cassette subfamily C member 9 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of ABCC9 mRNA; Sulfur Dioxide results in increased expression of ABCC9 protein |
CTD |
PMID:26112951 |
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NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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G |
Agr2 |
anterior gradient 2, protein disulphide isomerase family member |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA |
CTD |
PMID:29621558 |
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NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of AHR mRNA |
CTD |
PMID:32248990 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Akt1 |
AKT serine/threonine kinase 1 |
affects phosphorylation |
EXP |
Sulfur Dioxide affects the phosphorylation of AKT1 protein |
CTD |
PMID:32153200 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
App |
amyloid beta precursor protein |
multiple interactions |
EXP |
Sulfur Dioxide promotes the reaction [Particulate Matter results in increased cleavage of and results in increased localization of APP protein] |
CTD |
PMID:28565962 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arc |
activity-regulated cytoskeleton-associated protein |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of ARC mRNA |
CTD |
PMID:25534910 |
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NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA |
CTD |
PMID:29621558 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of BAX protein; [Sulfur Dioxide co-treated with sodium arsenite] results in increased expression of BAX mRNA |
CTD |
PMID:27521637 PMID:30195209 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of BCL2 mRNA Sulfur Dioxide results in decreased expression of BCL2 mRNA |
CTD |
PMID:30195209 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Becn1 |
beclin 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of CACNA1C mRNA; Sulfur Dioxide results in decreased expression of CACNA1C protein |
CTD |
PMID:26112951 |
|
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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G |
Cacna1d |
calcium voltage-gated channel subunit alpha1 D |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of CACNA1D mRNA; Sulfur Dioxide results in decreased expression of CACNA1D protein |
CTD |
PMID:26112951 |
|
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
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G |
Camk2a |
calcium/calmodulin-dependent protein kinase II alpha |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of CAMK2A protein modified form |
CTD |
PMID:25534910 |
|
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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G |
Capn1 |
calpain 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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G |
Casp1 |
caspase 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form] |
CTD |
PMID:30503585 |
|
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression decreases activity increases activity |
EXP ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein; Sulfur Dioxide results in increased expression of and results in increased activity of CASP3 protein Sulfur Dioxide results in increased expression of CASP3 mRNA [Sulfur Dioxide co-treated with sodium arsenite] results in increased activity of CASP3 protein; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein Sulfur Dioxide results in decreased activity of CASP3 protein [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA Sulfur Dioxide results in increased activity of CASP3 protein |
CTD |
PMID:19621461 PMID:21873648 PMID:26209559 PMID:30195209 PMID:30503585 PMID:31268311 PMID:32153200 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of CASP8 mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 protein [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA |
CTD |
PMID:19621461 PMID:30503585 PMID:31268311 PMID:35533050 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases expression multiple interactions increases activity |
EXP ISO |
Sulfur Dioxide results in increased expression of CASP9 mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP9 protein [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of CASP9 mRNA Sulfur Dioxide results in increased activity of CASP9 protein |
CTD |
PMID:19621461 PMID:30503585 PMID:31268311 PMID:32153200 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
decreases activity multiple interactions |
EXP |
Sulfur Dioxide results in decreased activity of CAT protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA] |
CTD |
PMID:10871429 PMID:30503585 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA |
CTD |
PMID:29621558 |
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NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of CCL2 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA] |
CTD |
PMID:27565714 PMID:30503585 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of CCL20 protein |
CTD |
PMID:27565714 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Cdh2 |
cadherin 2 |
multiple interactions decreases expression |
ISO |
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CDH2 protein Sulfur Dioxide results in decreased expression of CDH2 protein |
CTD |
PMID:27237588 |
|
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions increases expression decreases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A protein] Sulfur Dioxide results in increased expression of CDKN2A protein Sulfur Dioxide results in decreased expression of CDKN2A mRNA; Sulfur Dioxide results in decreased expression of CDKN2A protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Clca1 |
chloride channel accessory 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA |
CTD |
PMID:29621558 |
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NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
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G |
Cldn11 |
claudin 11 |
decreases expression multiple interactions |
ISO |
Sulfur Dioxide results in decreased expression of CLDN11 protein [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CLDN11 protein |
CTD |
PMID:27237588 |
|
NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of COX4I1 mRNA |
CTD |
PMID:22677886 |
|
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Ctnna1 |
catenin alpha 1 |
multiple interactions decreases expression |
ISO |
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CTNNA1 protein Sulfur Dioxide results in decreased expression of CTNNA1 protein |
CTD |
PMID:27237588 |
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NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of CXCL1 protein |
CTD |
PMID:27565714 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein] |
CTD |
PMID:30503585 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases activity decreases expression |
EXP |
Sulfur Dioxide results in decreased activity of CYP1A1 protein Sulfur Dioxide results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:16023800 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases activity decreases expression |
EXP |
Sulfur Dioxide results in decreased activity of CYP1A2 protein Sulfur Dioxide results in decreased expression of CYP1A2 mRNA |
CTD |
PMID:16023800 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of DDIT3 mRNA |
CTD |
PMID:31268311 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
affects expression |
EXP |
Sulfur Dioxide affects the expression of DLG4 protein |
CTD |
PMID:25534910 |
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NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of DNM1L protein |
CTD |
PMID:27521637 |
|
NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dsg2 |
desmoglein 2 |
multiple interactions decreases expression |
ISO |
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 mRNA; [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 protein Sulfur Dioxide results in decreased expression of DSG2 mRNA; Sulfur Dioxide results in decreased expression of DSG2 protein |
CTD |
PMID:27237588 |
|
NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of DUSP1 mRNA |
CTD |
PMID:32248990 |
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NCBI chr10:16,680,478...16,683,275
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G |
Edn1 |
endothelin 1 |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of EDN1 mRNA; Sulfur Dioxide results in increased expression of EDN1 protein [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein |
CTD |
PMID:20083630 PMID:30090456 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of FIS1 protein |
CTD |
PMID:27521637 |
|
NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS protein Sulfur Dioxide results in increased expression of FOS mRNA; Sulfur Dioxide results in increased expression of FOS protein |
CTD |
PMID:19408242 PMID:19434695 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Gemin4 |
gem (nuclear organelle) associated protein 4 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of GEMIN4 mRNA |
CTD |
PMID:32248990 |
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NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431 Ensembl chr10:61,066,425...61,073,431
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G |
Gja1 |
gap junction protein, alpha 1 |
decreases expression multiple interactions |
ISO |
Sulfur Dioxide results in decreased expression of GJA1 protein [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of GJA1 protein |
CTD |
PMID:27237588 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of GPX1 mRNA |
CTD |
PMID:32248990 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIA1 mRNA |
CTD |
PMID:25534910 |
|
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIA2 mRNA |
CTD |
PMID:25534910 |
|
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIN1 mRNA |
CTD |
PMID:25534910 |
|
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIN2A mRNA |
CTD |
PMID:25534910 |
|
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions increases cleavage decreases expression |
EXP |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased cleavage of GRIN2B protein] Sulfur Dioxide results in decreased expression of GRIN2B mRNA |
CTD |
PMID:21873648 PMID:25534910 |
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NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
GSTP1 gene SNP affects the susceptibility to [Air Pollutants results in increased abundance of Sulfur Dioxide] |
CTD |
PMID:22228263 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS protein] Sulfur Dioxide results in increased expression of HRAS mRNA; Sulfur Dioxide results in increased expression of HRAS protein |
CTD |
PMID:19408242 PMID:20064080 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein] [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of HSPA5 mRNA |
CTD |
PMID:30503585 PMID:31268311 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of ICAM1 mRNA; Sulfur Dioxide results in increased expression of ICAM1 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] |
CTD |
PMID:20083630 PMID:30503585 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Ifng |
interferon gamma |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of IFNG protein [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein |
CTD |
PMID:27565714 PMID:29621558 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of IKBKB mRNA |
CTD |
PMID:31268311 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of IL10 protein |
CTD |
PMID:27565714 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il13 |
interleukin 13 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IL13 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL17A protein |
CTD |
PMID:29621558 |
|
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of IL18 protein |
CTD |
PMID:27565714 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of IL1B protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] |
CTD |
PMID:27565714 PMID:30503585 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of IL2 protein |
CTD |
PMID:27565714 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL4 protein |
CTD |
PMID:29621558 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO EXP |
Sulfur Dioxide results in increased expression of IL6 protein [Sulfur Dioxide co-treated with Particulate Matter] results in increased expression of IL6 mRNA; [Sulfur Dioxide co-treated with Particulate Matter] results in increased expression of IL6 protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA] [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of IL6 protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of IL6 protein |
CTD |
PMID:20056584 PMID:27565714 PMID:28565962 PMID:30503585 PMID:31268311 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN protein Sulfur Dioxide results in increased expression of JUN mRNA; Sulfur Dioxide results in increased expression of JUN protein |
CTD |
PMID:19408242 PMID:19434695 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of KCNJ11 mRNA; Sulfur Dioxide results in increased expression of KCNJ11 protein |
CTD |
PMID:26112951 |
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NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
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G |
Kcnj8 |
potassium inwardly-rectifying channel, subfamily J, member 8 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of KCNJ8 mRNA; Sulfur Dioxide results in increased expression of KCNJ8 protein |
CTD |
PMID:26112951 |
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NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
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G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of KCNMA1 mRNA; Sulfur Dioxide results in increased expression of KCNMA1 protein |
CTD |
PMID:26112951 |
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NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
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G |
Kcnmb1 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of KCNMB1 mRNA; Sulfur Dioxide results in increased expression of KCNMB1 protein |
CTD |
PMID:26112951 |
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NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
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G |
Klf2 |
KLF transcription factor 2 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of KLF2 mRNA |
CTD |
PMID:32248990 |
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NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
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G |
Kras |
KRAS proto-oncogene, GTPase |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of KRAS mRNA; Sulfur Dioxide results in increased expression of KRAS protein |
CTD |
PMID:19434695 |
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NCBI chr 4:178,185,418...178,218,484
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Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions decreases expression |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of LHCGR mRNA Sulfur Dioxide results in decreased expression of LHCGR mRNA |
CTD |
PMID:30195209 |
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NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:30503585 |
|
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN1 protein |
CTD |
PMID:27521637 |
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NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein |
CTD |
PMID:27521637 |
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NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mir1224 |
microRNA 1224 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR1224 mRNA |
CTD |
PMID:31268311 |
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NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
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G |
Mir1249 |
microRNA 1249 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR1249 mRNA |
CTD |
PMID:30090456 |
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NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712
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G |
Mir125a |
microRNA 125a |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR125A mRNA |
CTD |
PMID:31268311 |
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NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
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G |
Mir146b |
microRNA 146b |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR146B mRNA |
CTD |
PMID:31268311 |
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NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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G |
Mir155 |
microRNA 155 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR155 mRNA |
CTD |
PMID:31268311 |
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NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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G |
Mir185 |
microRNA 185 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR185 mRNA |
CTD |
PMID:30090456 |
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NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
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G |
Mir186 |
microRNA 186 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR186 mRNA |
CTD |
PMID:31268311 |
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NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
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G |
Mir205 |
microRNA 205 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR205 mRNA |
CTD |
PMID:30090456 |
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NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
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G |
Mir21 |
microRNA 21 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR21 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mir210 |
microRNA 210 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR210 mRNA |
CTD |
PMID:31268311 |
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NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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G |
Mir30a |
microRNA 30a |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR30A mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
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G |
Mir30e |
microRNA 30e |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR30E mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
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G |
Mir320a |
microRNA 320a |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR320A mRNA |
CTD |
PMID:31268311 |
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NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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G |
Mir342 |
microRNA 342 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR342 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
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G |
Mir34b |
microRNA 34b |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR34B mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
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G |
Mir374b |
microRNA 374b |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR374B mRNA |
CTD |
PMID:31268311 |
|
NCBI chr X:68,591,732...68,591,799
Ensembl chr X:68,591,732...68,591,799
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G |
Mir375 |
microRNA 375 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR375 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
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G |
Mir425 |
microRNA 425 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR425 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637
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G |
Mir500 |
microRNA 500 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR500 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr X:15,258,778...15,258,857
Ensembl chr X:15,258,768...15,258,859
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Mir503 |
microRNA 503 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR503 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr X:132,806,303...132,806,373
Ensembl chr X:132,806,303...132,806,373
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G |
Mir504 |
microRNA 504 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR504 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr X:137,318,540...137,318,616
Ensembl chr X:137,318,540...137,318,616
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Mir615 |
microRNA 615 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR615 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 7:134,151,887...134,151,978
Ensembl chr 7:134,151,887...134,151,978
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Mir93 |
microRNA 93 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR93 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
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G |
Mirlet7i |
microRNA let-7i |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7I mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
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Mpo |
myeloperoxidase |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein] |
CTD |
PMID:30503585 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of ATP6 mRNA Sulfur Dioxide results in decreased expression of ATP6 mRNA |
CTD |
PMID:22677886 PMID:26980303 |
|
NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of ATP8 mRNA Sulfur Dioxide results in decreased expression of ATP8 mRNA |
CTD |
PMID:22677886 PMID:26980303 |
|
NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
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Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of COX1 mRNA Sulfur Dioxide results in decreased expression of COX1 mRNA |
CTD |
PMID:22677886 PMID:26980303 |
|
NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of COX2 mRNA |
CTD |
PMID:26980303 |
|
NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of COX3 mRNA |
CTD |
PMID:26980303 |
|
NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC protein] Sulfur Dioxide results in increased expression of MYC mRNA; Sulfur Dioxide results in increased expression of MYC protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MYD88 mRNA |
CTD |
PMID:31268311 |
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NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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G |
Nos1 |
nitric oxide synthase 1 |
increases activity |
EXP |
Sulfur Dioxide results in increased activity of NOS1 protein |
CTD |
PMID:32153200 |
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NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression multiple interactions increases activity |
EXP |
Sulfur Dioxide results in increased expression of NOS2 mRNA; Sulfur Dioxide results in increased expression of NOS2 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA] Sulfur Dioxide results in increased activity of NOS2 protein |
CTD |
PMID:20083630 PMID:30503585 PMID:32153200 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions affects phosphorylation |
ISO EXP |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of NOS3 protein Sulfur Dioxide affects the phosphorylation of NOS3 protein |
CTD |
PMID:30090456 PMID:32153200 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nrf1 |
nuclear respiratory factor 1 |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of NRF1 protein Sulfur Dioxide results in decreased expression of NRF1 mRNA; Sulfur Dioxide results in decreased expression of NRF1 protein |
CTD |
PMID:22677886 PMID:26980303 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of OPA1 protein |
CTD |
PMID:27521637 |
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NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
affects phosphorylation |
EXP |
Sulfur Dioxide affects the phosphorylation of PIK3R1 protein |
CTD |
PMID:32153200 |
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NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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G |
Pik3r2 |
phosphoinositide-3-kinase regulatory subunit 2 |
affects expression |
EXP |
Sulfur Dioxide affects the expression of PIK3R2 mRNA |
CTD |
PMID:32153200 |
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NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
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G |
Pla2g7 |
phospholipase A2 group VII |
affects expression |
ISO |
Sulfur Dioxide affects the expression of PLA2G7 |
CTD |
PMID:21356620 |
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NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions decreases expression |
ISO |
glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of PPARGC1A mRNA; Sulfur Dioxide results in decreased expression of PPARGC1A protein |
CTD |
PMID:26980303 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prg2 |
proteoglycan 2, pro eosinophil major basic protein |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of PRG2 mRNA |
CTD |
PMID:29621558 |
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NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101
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G |
Ptger2 |
prostaglandin E receptor 2 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of PTGER2 protein N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER2 protein] |
CTD |
PMID:21873648 |
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NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
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G |
Ptger4 |
prostaglandin E receptor 4 |
multiple interactions increases expression |
EXP |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER4 protein] |
CTD |
PMID:21873648 |
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NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
EXP ISO |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein] Sulfur Dioxide results in increased expression of PTGS2 mRNA; Sulfur Dioxide results in increased expression of PTGS2 protein 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of PTGS2 mRNA |
CTD |
PMID:20083630 PMID:21873648 PMID:26209559 PMID:32248990 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions increases expression decreases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein] Sulfur Dioxide results in increased expression of RB1 protein Sulfur Dioxide results in decreased expression of RB1 mRNA; Sulfur Dioxide results in decreased expression of RB1 protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Shbg |
sex hormone binding globulin |
multiple interactions |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of SHBG mRNA |
CTD |
PMID:30195209 |
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NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases activity |
EXP |
Sulfur Dioxide inhibits the reaction [Alloxan results in decreased activity of SOD1 protein] Sulfur Dioxide results in increased activity of SOD1 protein |
CTD |
PMID:10871429 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[[Air Pollutants results in increased abundance of Sulfur Dioxide] which affects the methylation of SOD2 promoter] which affects the methylation of SOD2 promoter |
CTD |
PMID:31220783 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sostdc1 |
sclerostin domain containing 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of SOSTDC1 mRNA |
CTD |
PMID:29621558 |
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NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of STAR mRNA |
CTD |
PMID:30195209 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Syp |
synaptophysin |
affects expression |
EXP |
Sulfur Dioxide affects the expression of SYP protein |
CTD |
PMID:25534910 |
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NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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G |
Tfam |
transcription factor A, mitochondrial |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of TFAM mRNA Sulfur Dioxide results in decreased expression of TFAM mRNA; Sulfur Dioxide results in decreased expression of TFAM protein |
CTD |
PMID:22677886 PMID:26980303 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of TGFB1 protein [Sulfur Dioxide co-treated with Particulate Matter] results in decreased expression of TGFB1 mRNA; [Sulfur Dioxide co-treated with Particulate Matter] results in decreased expression of TGFB1 protein |
CTD |
PMID:27565714 PMID:28565962 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tlr2 |
toll-like receptor 2 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of TLR2 mRNA |
CTD |
PMID:31268311 |
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NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TLR4 mRNA |
CTD |
PMID:32248990 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP ISO |
[Sulfur Dioxide co-treated with Particulate Matter] results in increased expression of TNF mRNA; [Sulfur Dioxide co-treated with Particulate Matter] results in increased expression of TNF protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TNF mRNA; TNF gene SNP affects the susceptibility to [[Air Pollutants results in increased abundance of Fuel Oils] which results in increased abundance of Sulfur Dioxide] |
CTD |
PMID:24056475 PMID:28565962 PMID:30503585 PMID:31268311 PMID:32248990 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TNFRSF1B mRNA |
CTD |
PMID:32248990 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tnfsf4 |
TNF superfamily member 4 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of TNFSF4 mRNA |
CTD |
PMID:29621558 |
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NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
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G |
Tp53 |
tumor protein p53 |
multiple interactions increases expression |
EXP ISO |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein] Sulfur Dioxide results in increased expression of TP53 mRNA; Sulfur Dioxide results in increased expression of TP53 protein [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of TRP53 protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 PMID:27521637 PMID:30503585 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Txnrd1 |
thioredoxin reductase 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TXNRD1 mRNA |
CTD |
PMID:32248990 |
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NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] |
CTD |
PMID:30503585 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of XBP1 mRNA |
CTD |
PMID:32248990 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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