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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cobamamide
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Accession:CHEBI:18408 term browser browse the term
Definition:A member of the class of cobalamins that is vitamin B12 in which the cyano group is replaced by a 5'-deoxyadenos-5'-yl moiety. It is one of the two metabolically active form of vitamin B12.
Synonyms:exact_synonym: Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-(5'-deoxy-5'-adenosyl)cobamide
 related_synonym: (5,6-dimethylbenzimidazolyl)cobamide coenzyme;   5'-Deoxy-5'-adenosyl vitamin B12;   5'-Deoxy-5'-adenosyl-5,6-dimethylbenzimidazolylcobamide;   5'-Deoxy-5'-adenosylcobalamin;   5'-deoxyadenosyl vitamin B12;   5'-deoxyadenosyl-5,6-dimethylbenzimidazolylcobamide;   5'-deoxyadenosylcobalamin;   5,6-Dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide;   5,6-Dimethylbenzimidazolyl-Co-5'-deoxy-5'-adenosylcobamide;   Adenosylcob(III)alamin;   AdoCbl;   Calomide;   Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-adenosylcobamide;   Cobalamin coenzyme;   Coenzyme B12;   DBC coenzyme;   DMBC coenzyme;   Deoxyadenosylcobalamin;   Dibencozide;   Formula=C72H100CoN18O17P;   Funacomide;   InChI=1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;4-,6-,7-,10-;/m11./s1;   InChIKey=ZIHHMGTYZOSFRC-OUCXYWSSSA-L;   SMILES=[H][C@]12[C@H](CC(N)=O)[C@@]3(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@@H]4[C@@H](CO)O[C@@H]([C@@H]4O)n4c[n+](c5cc(C)c(C)cc45)[Co-3]456(C[C@H]7O[C@H]([C@H](O)[C@@H]7O)n7cnc8c(N)ncnc78)N1C3=C(C)C1=[N+]4C(=CC3=[N+]5C(=C(C)C4=[N+]6[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]3CCC(N)=O)C(C)(C)[C@@H]1CCC(N)=O;   Vitamin B12 coenzyme;   adenosylcobalamin;   alpha-(5,6-Dimethylbenzimidazolyl)cobamide coenzyme;   cobamamid;   cobamamida;   cobamamidum;   cobamide coenzyme;   coenzyme B-12
 alt_id: CHEBI:13739;   CHEBI:23340;   CHEBI:3797
 xref: Beilstein:4122932;   CAS:13870-90-1;   DrugBank:DB11191;   Gmelin:439994;   HMDB:HMDB0002086;   KEGG:C00194
 xref_mesh: MESH:C000913
 xref: MetaCyc:ADENOSYLCOBALAMIN;   PDBeChem:B1Z;   PMID:11792214;   PMID:12093296;   PMID:17011224;   Reaxys:4122932;   Wikipedia:Cobamamide


show annotations for term's descendants           Sort by:
cobamamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO cobamamide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        biochemical role 19596
          cofactor 16592
            cobamamide 1
              adenosylcobalamin 5'-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            organic molecule 19755
                              organic cyclic compound 19545
                                organic heterocyclic compound 18906
                                  organonitrogen heterocyclic compound 18155
                                    polypyrrole 695
                                      tetrapyrrole 583
                                        cyclic tetrapyrrole 454
                                          metallotetrapyrrole 419
                                            cobalt corrinoid 110
                                              cobalt-corrinoid hexaamide 110
                                                cobamides 110
                                                  cobalamins 110
                                                    cobamamide 1
                                                      adenosylcobalamin 5'-phosphate 0
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