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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:14-demethyllanosterol
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Accession:CHEBI:18364 term browser browse the term
Definition:A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
Synonyms:related_synonym: (3beta,5alpha)-4,4-dimethylcholesta-8,24-dien-3-ol;   14-desmethyllanosterol;   4,4-Dimethyl-5alpha-cholesta-8,24-dien-3beta-ol;   4,4-Dimethyl-8,24-cholestadienol;   4,4-dimethylcholesta-8(9),24-dien-3beta-ol;   4,4-dimethylzymosterol;   Formula=C29H48O;   InChI=1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1;   InChIKey=CHGIKSSZNBCNDW-QGBOJXOESA-N;   SMILES=C12=C([C@]3([C@]([C@](CC3)([C@@H](CCC=C(C)C)C)[H])(C)CC1)[H])CC[C@@]4([C@@]2(CC[C@@H](C4(C)C)O)C)[H]
 alt_id: CHEBI:11921;   CHEBI:19151;   CHEBI:755
 xref: Beilstein:2302110;   CAS:7448-02-4;   KEGG:C05108;   KNApSAcK:C00023776
 xref_mesh: MESH:C013499
 xref: Reaxys:2302110


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14-demethyllanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol CTD PMID:23125191 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          metabolite 19562
            eukaryotic metabolite 19390
              plant metabolite 18000
                lanosterol 7
                  14-demethyllanosterol 1
                    4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            organic molecule 19737
                              organic cyclic compound 19526
                                organic polycyclic compound 17311
                                  steroid 14705
                                    hydroxy steroid 14469
                                      3-hydroxy steroid 12811
                                        sterol 467
                                          3beta-sterol 461
                                            lanosterol 7
                                              14-demethyllanosterol 1
                                                4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
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