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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Lucidone
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Accession:CHEBI:183569 term browser browse the term
Synonyms:exact_synonym: 3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one
 related_synonym: Formula=C15H12O4;   InChI=1S/C15H12O4/c1-19-13-9-12(17)14(15(13)18)11(16)8-7-10-5-3-2-4-6-10/h2-9,18H,1H3/b8-7+;   InChIKey=ANPTXNYQLGJVRE-BQYQJAHWSA-N;   SMILES=O(C=1C(O)=C(C(=O)C1)C(=O)/C=C/C2=CC=CC=C2)C
 xref: Chemspider:9428886;   LIPID_MAPS_instance:LMPK12120439
 xref_mesh: MESH:C529637



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Lucidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO lucidone results in increased expression of HMOX1 protein
[lucidone co-treated with 2,2'-azobis(2-amidinopropane)] results in increased expression of HMOX1 protein; lucidone inhibits the reaction [Ethanol results in decreased expression of HMOX1 mRNA]; lucidone inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]
CTD PMID:22484158 PMID:23712098 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects response to substance
ISO [lucidone co-treated with 2,2'-azobis(2-amidinopropane)] affects the localization of and results in increased activity of NFE2L2 protein; [lucidone co-treated with Ethanol] results in increased expression of NFE2L2 mRNA; lucidone affects the localization of and results in increased activity of NFE2L2 protein; lucidone promotes the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of NFE2L2 protein]
NFE2L2 protein affects the susceptibility to lucidone
CTD PMID:22484158 PMID:23712098 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased degradation of NFKBIA protein] CTD PMID:23712098 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of PTGS2 protein] CTD PMID:23712098 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) affects the localization of RELA protein] CTD PMID:23712098 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO lucidone inhibits the reaction [Ethanol results in increased expression of TNF] CTD PMID:22484158 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      atom 19878
        nonmetal atom 19800
          carbon atom 19754
            organic molecular entity 19754
              olefinic compound 16972
                Lucidone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      monocarboxylic acid 18004
                                        alpha,beta-unsaturated monocarboxylic acid 13458
                                          cinnamic acids 2544
                                            cinnamic acid 38
                                              Lucidone 6
paths to the root