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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases activity multiple interactions |
EXP ISO |
Penicillin G results in increased activity of ABCC2 protein Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide] |
CTD |
PMID:12702717 PMID:15904671 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases transport |
ISO |
ABCC4 protein results in increased transport of Penicillin G |
CTD |
PMID:17939016 |
|
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of ACACA mRNA Penicillin G results in increased expression of ACACA mRNA |
CTD |
PMID:27503388 |
|
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acly |
ATP citrate lyase |
increases expression multiple interactions |
ISO |
Penicillin G results in increased expression of ACLY mRNA [Penicillin G co-treated with Erythromycin] results in increased expression of ACLY mRNA |
CTD |
PMID:27503388 |
|
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Afp |
alpha-fetoprotein |
affects expression decreases expression |
ISO |
Penicillin G affects the expression of AFP mRNA Penicillin G results in decreased expression of AFP mRNA |
CTD |
PMID:24737281 PMID:25137620 PMID:26272751 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Anxa8 |
annexin A8 |
decreases expression |
ISO |
Penicillin G results in decreased expression of ANXA8 mRNA |
CTD |
PMID:24737281 |
|
NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
Penicillin G results in increased expression of ATF3 mRNA |
CTD |
PMID:27965148 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of CCL2 mRNA Penicillin G results in increased expression of CCL2 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of CCR2 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of CD36 mRNA Penicillin G results in increased expression of CD36 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
Penicillin G results in increased expression of CD86 protein |
CTD |
PMID:19665512 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cer1 |
cerberus 1, DAN family BMP antagonist |
increases expression |
ISO |
Penicillin G results in increased expression of CER1 mRNA |
CTD |
PMID:26272751 |
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NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
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G |
Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
Penicillin G results in increased expression of CES1 mRNA |
CTD |
PMID:22609641 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of CPT1A mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Crp |
C-reactive protein |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of CRP mRNA |
CTD |
PMID:27503388 |
|
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cs |
citrate synthase |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of CS mRNA Penicillin G results in increased expression of CS mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Dcn |
decorin |
decreases expression |
ISO |
Penicillin G results in decreased expression of DCN mRNA |
CTD |
PMID:24737281 |
|
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
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G |
Defb1 |
defensin beta 1 |
decreases expression multiple interactions |
ISO |
Penicillin G results in decreased expression of DEFB1 mRNA [Penicillin G co-treated with Erythromycin] results in decreased expression of DEFB1 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of DGAT1 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of DGAT2 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of FABP1 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fasn |
fatty acid synthase |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of FASN mRNA Penicillin G results in increased expression of FASN mRNA |
CTD |
PMID:27503388 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Frzb |
frizzled-related protein |
decreases expression |
ISO |
Penicillin G results in decreased expression of FRZB mRNA |
CTD |
PMID:24737281 |
|
NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
Penicillin G results in increased expression of GCLM mRNA |
CTD |
PMID:22609641 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression multiple interactions |
ISO |
Penicillin G results in increased expression of GPAM mRNA [Penicillin G co-treated with Erythromycin] results in increased expression of GPAM mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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G |
Hdac7 |
histone deacetylase 7 |
increases expression |
ISO |
Penicillin G results in increased expression of HDAC7 mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072
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G |
Ifng |
interferon gamma |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of IFNG mRNA Penicillin G results in increased expression of IFNG mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf2 |
insulin-like growth factor 2 |
decreases expression |
ISO |
Penicillin G results in decreased expression of IGF2 mRNA |
CTD |
PMID:24737281 |
|
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
decreases expression |
ISO |
Penicillin G results in decreased expression of IGFBP5 mRNA |
CTD |
PMID:24737281 |
|
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Il18 |
interleukin 18 |
increases expression |
ISO |
Penicillin G results in increased expression of IL18 protein |
CTD |
PMID:23063874 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
increases expression multiple interactions |
ISO |
Penicillin G results in increased expression of IL1A mRNA [Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
increases expression |
ISO |
Penicillin G results in increased expression of IL1B mRNA |
CTD |
PMID:22609641 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of IL6 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Penicillin G results in increased expression of JUN mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kdr |
kinase insert domain receptor |
increases expression decreases expression |
ISO |
Penicillin G results in increased expression of KDR mRNA Penicillin G results in decreased expression of KDR mRNA |
CTD |
PMID:25137620 PMID:26272751 |
|
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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G |
Lbp |
lipopolysaccharide binding protein |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of LBP mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
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G |
Mesp1 |
mesoderm posterior bHLH transcription factor 1 |
decreases expression |
ISO |
Penicillin G results in decreased expression of MESP1 mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
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G |
Mmp1 |
matrix metallopeptidase 1 |
decreases expression |
ISO |
Penicillin G results in decreased expression of MMP1 mRNA |
CTD |
PMID:24737281 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression multiple interactions |
ISO |
Penicillin G results in increased expression of MTTP mRNA [Penicillin G co-treated with Erythromycin] results in increased expression of MTTP mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
|
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G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in decreased expression of MUC2 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
ISO |
Penicillin G results in increased expression of MYC mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nefm |
neurofilament medium chain |
affects expression |
ISO |
Penicillin G affects the expression of NEFM mRNA |
CTD |
PMID:25137620 |
|
NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
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G |
Nes |
nestin |
increases expression affects expression |
EXP ISO |
Penicillin G results in increased expression of NES protein Penicillin G affects the expression of NES mRNA |
CTD |
PMID:16137769 PMID:16369854 PMID:25137620 |
|
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of NFKB1 mRNA Penicillin G results in increased expression of NFKB1 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
Penicillin G results in increased expression of NQO1 mRNA |
CTD |
PMID:22609641 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Pgd |
phosphogluconate dehydrogenase |
decreases activity |
EXP |
Penicillin G results in decreased activity of PGD protein |
CTD |
PMID:15558954 |
|
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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G |
Pir |
pirin |
increases expression |
ISO |
Penicillin G results in increased expression of PIR mRNA |
CTD |
PMID:22609641 |
|
NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
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G |
Pnpla6 |
patatin-like phospholipase domain containing 6 |
decreases expression |
ISO |
Penicillin G results in decreased expression of PNPLA6 mRNA |
CTD |
PMID:25137620 |
|
NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
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G |
Reg3g |
regenerating family member 3 gamma |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in decreased expression of REG3G mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
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G |
Retnlb |
resistin like beta |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in decreased expression of RETNLB mRNA |
CTD |
PMID:27503388 |
|
NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of SCD1 mRNA Penicillin G results in increased expression of SCD1 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Shh |
sonic hedgehog signaling molecule |
increases expression |
ISO |
Penicillin G results in increased expression of SHH mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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G |
Slc22a12 |
solute carrier family 22 member 12 |
multiple interactions |
ISO |
Potassium promotes the reaction [SLC22A12 protein results in increased uptake of Penicillin G] |
CTD |
PMID:15284287 |
|
NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
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G |
Slc22a20 |
solute carrier family 22 member 20 |
multiple interactions |
ISO |
Penicillin G inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] |
CTD |
PMID:16478971 |
|
NCBI chr 1:203,257,374...203,273,854
Ensembl chr 1:203,257,374...203,273,822
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G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions |
ISO |
Penicillin G inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] |
CTD |
PMID:11602689 |
|
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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G |
Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions increases uptake |
EXP ISO |
Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G]; tranilast inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G] resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G] |
CTD |
PMID:10224140 PMID:15319347 PMID:17255469 PMID:27377006 PMID:35019195 |
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NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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G |
Slc27a2 |
solute carrier family 27 member 2 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of SLC27A2 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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|
G |
Slco3a1 |
solute carrier organic anion transporter family, member 3a1 |
multiple interactions |
ISO |
Penicillin G promotes the reaction [SLCO3A1 protein results in increased uptake of simvastatin acid] |
CTD |
PMID:28887287 |
|
NCBI chr 1:128,106,232...128,388,043
Ensembl chr 1:128,106,228...128,387,925
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|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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|
G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA |
CTD |
PMID:27503388 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO |
[Penicillin G co-treated with Erythromycin] results in increased expression of TNF mRNA Penicillin G results in increased expression of TNF mRNA |
CTD |
PMID:27503388 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
G |
Trim16 |
tripartite motif-containing 16 |
increases expression |
ISO |
Penicillin G results in increased expression of TRIM16 mRNA |
CTD |
PMID:22609641 |
|
NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907
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|
G |
Ttr |
transthyretin |
decreases expression |
ISO |
Penicillin G results in decreased expression of TTR mRNA |
CTD |
PMID:24737281 |
|
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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G |
Wnt3 |
Wnt family member 3 |
increases expression |
ISO |
Penicillin G results in increased expression of WNT3 mRNA |
CTD |
PMID:26272751 |
|
NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099
|
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