|
G |
Abi3bp |
ABI family member 3 binding protein |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of ABI3BP mRNA |
CTD |
PMID:34036453 |
|
NCBI chr11:43,912,187...44,128,888
|
|
G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ADAMTS1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr11:38,418,565...38,427,384
|
|
G |
Adgra2 |
adhesion G protein-coupled receptor A2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of ADGRA2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr16:64,932,964...64,971,433
|
|
G |
Adm2 |
adrenomedullin 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ADM2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:120,393,179...120,394,965
|
|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
3-nitrobenzanthrone binds to and results in increased activity of AHR protein |
CTD |
PMID:28186253 |
|
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
multiple interactions increases reduction |
ISO |
[AKR1C1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [AKR1C1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone |
CTD |
PMID:30406992 |
|
NCBI chr17:70,720,397...70,747,285
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
multiple interactions increases reduction |
ISO |
[AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [AKR1C2 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone |
CTD |
PMID:30406992 |
|
NCBI chr17:70,669,684...70,717,935
|
|
G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases reduction multiple interactions |
ISO |
AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone [AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone |
CTD |
PMID:30406992 |
|
NCBI chr17:71,020,884...71,037,779
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
3-nitrobenzanthrone results in increased expression of and results in increased phosphorylation of AKT1 protein; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:34036453 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Ang |
angiogenin |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ANG mRNA |
CTD |
PMID:34036453 |
|
NCBI chr15:24,312,711...24,323,361
|
|
G |
Apoe |
apolipoprotein E |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of APOE mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:88,481,889...88,485,816
|
|
G |
Arap2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ARAP2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr14:50,921,323...51,120,972
|
|
G |
Areg |
amphiregulin |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of AREG mRNA |
CTD |
PMID:34036453 |
|
NCBI chr14:17,256,384...17,265,641
|
|
G |
Bicc1 |
BicC family RNA binding protein 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of BICC1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:17,449,639...17,686,775
|
|
G |
Bmp4 |
bone morphogenetic protein 4 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of BMP4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr15:22,098,191...22,113,145
|
|
G |
Bmper |
BMP-binding endothelial regulator |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of BMPER mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 8:30,008,049...30,253,201
|
|
G |
Bnc2 |
basonuclin zinc finger protein 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of BNC2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 5:103,724,934...104,061,890
|
|
G |
Btg1 |
BTG anti-proliferation factor 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of BTG1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:33,228,149...33,230,406
|
|
G |
Cav1 |
caveolin 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of CAV1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:46,606,538...46,639,616
|
|
G |
Ccbe1 |
collagen and calcium binding EGF domains 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CCBE1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr18:61,849,821...62,093,876
|
|
G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of CD24 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:47,074,353...47,079,662
|
|
G |
Cd34 |
CD34 molecule |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of CD34 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr13:109,008,786...109,029,317
|
|
G |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CDH1 mRNA; 3-nitrobenzanthrone results in decreased expression of CDH1 protein |
CTD |
PMID:34036453 |
|
NCBI chr19:51,402,178...51,471,572
|
|
G |
Cdk14 |
cyclin-dependent kinase 14 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CDK14 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:29,619,237...30,213,651
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of CDKN1A protein |
CTD |
PMID:25230394 |
|
NCBI chr20:7,150,820...7,161,373
|
|
G |
Chrdl1 |
chordin-like 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CHRDL1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr X:106,889,125...106,992,937
|
|
G |
Cldn3 |
claudin 3 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CLDN3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr12:27,345,075...27,346,547
|
|
G |
Col18a1 |
collagen type XVIII alpha 1 chain |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of COL18A1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:11,474,104...11,582,593
|
|
G |
Col5a2 |
collagen type V alpha 2 chain |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of COL5A2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 9:54,940,768...55,090,151
|
|
G |
Col6a1 |
collagen type VI alpha 1 chain |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of COL6A1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:11,905,690...11,924,111
|
|
G |
Ctnnb1 |
catenin beta 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CTNNB1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 8:129,517,576...129,544,661
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of CXCL14 mRNA |
CTD |
PMID:19879285 |
|
NCBI chr17:8,323,150...8,331,176
|
|
G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of CXCR4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr13:42,630,383...42,634,288
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
CYP1A1 protein affects the reaction [3-nitrobenzanthrone results in increased abundance of Reactive Oxygen Species] 3-nitrobenzanthrone results in increased expression of CYP1A1 mRNA |
CTD |
PMID:17477947 PMID:25230394 |
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of CYP1B1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 6:21,093,927...21,103,091
|
|
G |
Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of DDR2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr13:84,726,412...84,851,032
|
|
G |
Dsc2 |
desmocollin 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of DSC2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr18:11,725,466...11,757,591
|
|
G |
Ecm1 |
extracellular matrix protein 1 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of ECM1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 2:183,287,491...183,292,729
|
|
G |
Epcam |
epithelial cell adhesion molecule |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of EPCAM mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 6:12,633,715...12,649,678
|
|
G |
Eps8l1 |
EPS8 signaling adaptor L1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of EPS8L1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:69,343,202...69,359,778
|
|
G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ERBB2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:83,907,491...83,931,365
|
|
G |
Ereg |
epiregulin |
increases expression multiple interactions |
ISO |
3-nitrobenzanthrone results in increased expression of EREG mRNA; 3-nitrobenzanthrone results in increased expression of EREG protein EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of SOX9 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of TWIST2 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of AKT1 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]; EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:34036453 |
|
NCBI chr14:17,311,485...17,325,260
|
|
G |
Etv4 |
ETS variant transcription factor 4 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of ETV4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:86,706,749...86,721,974
|
|
G |
F11r |
F11 receptor |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of F11R mRNA |
CTD |
PMID:34036453 |
|
NCBI chr13:86,406,229...86,429,819
|
|
G |
Fbln1 |
fibulin 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of FBLN1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:116,310,582...116,390,075
|
|
G |
Fbln5 |
fibulin 5 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of FBLN5 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 6:120,899,219...120,977,829
|
|
G |
Fgf18 |
fibroblast growth factor 18 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of FGF18 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:17,706,011...17,737,702
|
|
G |
Fgf2 |
fibroblast growth factor 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of FGF2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 2:122,164,454...122,218,796
|
|
G |
Fgf9 |
fibroblast growth factor 9 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of FGF9 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr15:32,208,993...32,254,952
|
|
G |
Fgfr2 |
fibroblast growth factor receptor 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of FGFR2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:194,175,703...194,280,914
|
|
G |
Flt4 |
Fms related receptor tyrosine kinase 4 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of FLT4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:34,414,834...34,455,878
|
|
G |
Foxo4 |
forkhead box O4 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of FOXO4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr X:66,385,241...66,392,115
|
|
G |
Fst |
follistatin |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of FST mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 2:47,856,345...47,863,670
|
|
G |
Gdf6 |
growth differentiation factor 6 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of GDF6 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 5:27,793,561...27,809,884
|
|
G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of GREM1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 3:100,512,317...100,524,001
|
|
G |
Hipk2 |
homeodomain interacting protein kinase 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of HIPK2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:68,399,358...68,586,404
|
|
G |
Hoxb3 |
homeo box B3 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of HOXB3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:81,258,739...81,314,134
|
|
G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
multiple interactions |
ISO |
[NAT2 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene; [SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene |
CTD |
PMID:17483118 |
|
NCBI chr X:132,736,175...132,768,149
|
|
G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ID2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 6:47,469,162...47,470,995
|
|
G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of IGFBP4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:84,491,471...84,503,487
|
|
G |
Il15 |
interleukin 15 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of IL15 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr19:42,536,160...42,611,349
|
|
G |
Il18 |
interleukin 18 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of IL18 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 8:59,802,072...59,829,275
|
|
G |
Il1b |
interleukin 1 beta |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of IL1B mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il6 |
interleukin 6 |
increases expression multiple interactions increases secretion |
ISO |
3-nitrobenzanthrone results in increased expression of IL6 mRNA IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein] 3-nitrobenzanthrone results in increased secretion of IL6 protein |
CTD |
PMID:34036453 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Inhba |
inhibin subunit beta A |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of INHBA mRNA |
CTD |
PMID:34036453 |
|
NCBI chr17:53,787,159...53,810,942
|
|
G |
Irf6 |
interferon regulatory factor 6 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of IRF6 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr13:104,672,179...104,691,386
|
|
G |
Isl1 |
ISL LIM homeobox 1 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of ISL1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 2:49,813,618...49,823,442
|
|
G |
Itga1 |
integrin subunit alpha 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ITGA1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 2:48,379,181...48,545,336
|
|
G |
Itgb1bp1 |
integrin subunit beta 1 binding protein 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of ITGB1BP1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 6:46,549,994...46,564,735
|
|
G |
Itgb3 |
integrin subunit beta 3 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of ITGB3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:90,009,927...90,067,787
|
|
G |
Itm2a |
integral membrane protein 2A |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of ITM2A mRNA |
CTD |
PMID:34036453 |
|
NCBI chr X:72,486,383...72,492,344
|
|
G |
Jam2 |
junctional adhesion molecule 2 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of JAM2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr11:37,316,287...37,366,517
|
|
G |
Jcad |
junctional cadherin 5 associated |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of JCAD mRNA |
CTD |
PMID:34036453 |
|
NCBI chr17:53,089,382...53,130,996
|
|
G |
Krt7 |
keratin 7 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of KRT7 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:134,407,626...134,423,787
|
|
G |
Lad1 |
ladinin 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of LAD1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr13:47,249,605...47,263,967
|
|
G |
Llgl2 |
LLGL scribble cell polarity complex component 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of LLGL2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:101,050,978...101,086,527
|
|
G |
Lum |
lumican |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of LUM mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:34,245,323...34,252,510
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:34036453 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:34036453 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of MET mRNA; 3-nitrobenzanthrone results in increased expression of MET protein |
CTD |
PMID:34036453 |
|
NCBI chr 4:46,756,823...46,864,041
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of MMP2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr19:30,327,643...30,355,856
|
|
G |
Myo1d |
myosin ID |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of MYO1D mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:65,489,153...65,765,812
|
|
G |
Myo5c |
myosin VC |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of MYO5C mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 8:84,870,031...84,946,996
|
|
G |
Nat1 |
N-acetyltransferase 1 |
multiple interactions increases activity |
ISO |
[NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone NAT1 protein results in increased activity of 3-nitrobenzanthrone |
CTD |
PMID:15805261 PMID:20545351 |
|
NCBI chr16:22,218,217...22,238,516
|
|
G |
Nat2 |
N-acetyltransferase 2 |
multiple interactions increases activity increases response to substance |
ISO |
[NAT2 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] NAT2 protein results in increased activity of 3-nitrobenzanthrone NAT2 protein results in increased susceptibility to 3-nitrobenzanthrone |
CTD |
PMID:15805261 PMID:17483118 PMID:20545351 |
|
NCBI chr16:26,974,874...27,005,191
|
|
G |
Ndrg1 |
N-myc downstream regulated 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of NDRG1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:100,573,526...100,614,902
|
|
G |
Nf1 |
neurofibromin 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of NF1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:64,803,986...65,037,086
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
affects metabolic processing affects response to substance multiple interactions |
ISO |
NFE2L2 protein affects the metabolism of 3-nitrobenzanthrone NFE2L2 protein affects the susceptibility to 3-nitrobenzanthrone [NFE2L2 protein affects the metabolism of 3-nitrobenzanthrone] which affects the abundance of 3-aminobenzanthrone |
CTD |
PMID:31746589 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression increases activity increases metabolic processing affects binding multiple interactions increases reduction |
ISO |
3-nitrobenzanthrone results in increased expression of NQO1 mRNA NQO1 protein results in increased activity of 3-nitrobenzanthrone NQO1 protein results in increased metabolism of 3-nitrobenzanthrone 3-nitrobenzanthrone binds to NQO1 protein [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [NQO1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone; [NQO1 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone |
CTD |
PMID:15805261 PMID:20545351 PMID:25230394 PMID:28922594 PMID:30406992 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of NR4A1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:132,368,399...132,389,300
|
|
G |
Nrp1 |
neuropilin 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of NRP1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr19:73,256,557...73,411,705
|
|
G |
Nrp2 |
neuropilin 2 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of NRP2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 9:71,616,602...71,731,869
|
|
G |
Oas1a |
2'-5' oligoadenylate synthetase 1A |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of OAS1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr12:35,669,798...35,680,505
|
|
G |
Pdpn |
podoplanin |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PDPN mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 5:155,601,691...155,635,656
|
|
G |
Pkn1 |
protein kinase N1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PKN1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr19:41,346,855...41,374,832
|
|
G |
Plxnd1 |
plexin D1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PLXND1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:149,002,786...149,043,097
|
|
G |
Pmp22 |
peripheral myelin protein 22 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PMP22 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:48,294,932...48,324,941
|
|
G |
Por |
cytochrome p450 oxidoreductase |
multiple interactions |
ISO |
[POR protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; POR protein results in increased activity of and results in increased reduction of 3-nitrobenzanthrone |
CTD |
PMID:20545351 |
|
NCBI chr12:26,587,674...26,655,612
|
|
G |
Ppfibp2 |
PPFIA binding protein 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PPFIBP2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:161,504,774...161,687,339
|
|
G |
Ppl |
periplakin |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PPL mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:10,450,919...10,496,575
|
|
G |
Ptx3 |
pentraxin 3 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of PTX3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 2:152,797,563...152,803,372
|
|
G |
Pycard |
PYD and CARD domain containing |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of PYCARD mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:192,032,124...192,033,419
|
|
G |
Ramp2 |
receptor activity modifying protein 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of RAMP2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:86,689,148...86,690,956
|
|
G |
RT1-Hb-ps1 |
RT1 class II, locus Hb, pseudogene 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of HLA-DPB1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:4,775,598...4,779,590
|
|
G |
Sema3e |
semaphorin 3E |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of SEMA3E mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:20,297,534...20,555,287
|
|
G |
Sfrp1 |
secreted frizzled-related protein 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of SFRP1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr16:75,278,325...75,316,736
|
|
G |
Slc37a1 |
solute carrier family 37 member 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of SLC37A1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:9,360,501...9,433,895
|
|
G |
Slit2 |
slit guidance ligand 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of SLIT2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr14:66,829,661...67,168,517
|
|
G |
Snai2 |
snail family transcriptional repressor 2 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of SNAI2 mRNA; 3-nitrobenzanthrone results in increased expression of SNAI2 protein |
CTD |
PMID:34036453 |
|
NCBI chr11:99,686,934...99,690,349
|
|
G |
Snai3 |
snail family transcriptional repressor 3 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of SNAI3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr19:67,425,311...67,437,830
|
|
G |
Sox9 |
SRY-box transcription factor 9 |
increases expression multiple interactions |
ISO |
3-nitrobenzanthrone results in increased expression of SOX9 mRNA; 3-nitrobenzanthrone results in increased expression of SOX9 protein EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of SOX9 protein] |
CTD |
PMID:34036453 |
|
NCBI chr10:98,305,744...98,311,250
|
|
G |
Spint1 |
serine peptidase inhibitor, Kunitz type 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of SPINT1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 3:126,685,017...126,697,957
|
|
G |
Spock3 |
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of SPOCK3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr16:26,382,895...26,815,943
|
|
G |
Srf |
serum response factor |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of SRF mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 9:21,924,050...21,933,338
|
|
G |
Srgn |
serglycin |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of SRGN mRNA |
CTD |
PMID:34036453 |
|
NCBI chr20:30,985,508...31,022,296
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of STAT1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 9:56,911,522...56,951,926
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
increases phosphorylation multiple interactions |
ISO |
3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein]; IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:34036453 |
|
NCBI chr10:86,311,528...86,363,513
|
|
G |
Sulf1 |
sulfatase 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of SULF1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 5:6,362,894...6,526,174
|
|
G |
Sult1a1 |
sulfotransferase family 1A member 1 |
multiple interactions increases response to substance increases activity |
ISO |
[NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; [SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene SULT1A1 protein results in increased susceptibility to 3-nitrobenzanthrone SULT1A1 protein results in increased activity of 3-nitrobenzanthrone |
CTD |
PMID:15805261 PMID:17483118 PMID:20545351 |
|
NCBI chr 1:190,702,592...190,706,112
|
|
G |
Syne1 |
spectrin repeat containing nuclear envelope protein 1 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of SYNE1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:41,512,146...41,983,382
|
|
G |
Tcf4 |
transcription factor 4 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of TCF4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr18:65,216,840...65,563,186
|
|
G |
Thbs1 |
thrombospondin 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of THBS1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 3:125,510,250...125,525,402
|
|
G |
Thbs2 |
thrombospondin 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of THBS2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 1:64,343,523...64,372,918
|
|
G |
Timp4 |
TIMP metallopeptidase inhibitor 4 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of TIMP4 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:148,306,021...148,312,558
|
|
G |
Tjp3 |
tight junction protein 3 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of TJP3 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 7:8,427,650...8,446,279
|
|
G |
Tnc |
tenascin C |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of TNC mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 5:82,391,340...82,476,197
|
|
G |
Tnfsf12 |
TNF superfamily member 12 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of TNFSF12 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:54,902,616...54,912,628
|
|
G |
Tns1 |
tensin 1 |
affects expression |
ISO |
3-nitrobenzanthrone affects the expression of TNS1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 9:75,491,886...75,702,853
|
|
G |
Tom1l1 |
target of myb1 like 1 membrane trafficking protein |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of TOM1L1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr10:75,464,577...75,508,304
|
|
G |
Tp53 |
tumor protein p53 |
decreases expression increases expression increases mutagenesis |
ISO |
3-nitrobenzanthrone results in decreased expression of TP53 mRNA; 3-nitrobenzanthrone results in decreased expression of TP53 protein 3-nitrobenzanthrone results in increased expression of TRP53 protein 3-nitrobenzanthrone results in increased mutagenesis of TP53 gene |
CTD |
PMID:18765419 PMID:25230394 PMID:34036453 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Twist1 |
twist family bHLH transcription factor 1 |
increases expression affects expression |
ISO |
3-nitrobenzanthrone results in increased expression of TWIST1 protein 3-nitrobenzanthrone affects the expression of TWIST1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 6:50,674,910...50,676,904
|
|
G |
Twist2 |
twist family bHLH transcription factor 2 |
multiple interactions increases expression |
ISO |
EREG protein affects the reaction [3-nitrobenzanthrone results in increased expression of TWIST2 protein] 3-nitrobenzanthrone results in increased expression of TWIST2 mRNA; 3-nitrobenzanthrone results in increased expression of TWIST2 protein |
CTD |
PMID:34036453 |
|
NCBI chr 9:99,822,242...99,866,722
|
|
G |
Vamp8 |
vesicle-associated membrane protein 8 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of VAMP8 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 4:104,442,383...104,452,884
|
|
G |
Zeb1 |
zinc finger E-box binding homeobox 1 |
increases expression |
ISO |
3-nitrobenzanthrone results in increased expression of ZEB1 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr17:56,644,397...56,811,155
|
|
G |
Zeb2 |
zinc finger E-box binding homeobox 2 |
decreases expression |
ISO |
3-nitrobenzanthrone results in decreased expression of ZEB2 mRNA |
CTD |
PMID:34036453 |
|
NCBI chr 3:29,214,581...29,344,890
|
|