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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-phenyl-3-furoxancarbonitrile
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Accession:CHEBI:180495 term browser browse the term
Definition:A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation.
Synonyms:exact_synonym: 4-phenyl-1,2,5-oxadiazole-3-carbonitrile 2-oxide
 related_synonym: 2-oxo-4-phenyl-1,2,5lambda(5)-oxadiazole-3-carbonitrile;   3-cyano-4-phenylfurazan 2-oxide;   Formula=C9H5N3O2;   InChI=1S/C9H5N3O2/c10-6-8-9(11-14-12(8)13)7-4-2-1-3-5-7/h1-5H;   InChIKey=PMYJGTWUVVVOFO-UHFFFAOYSA-N;   RVC-589;   SMILES=[O-][N+]1=C(C#N)C(=NO1)C1=CC=CC=C1
 xref: CAS:125520-62-9;   Chemspider:1692
 xref_mesh: MESH:C090933
 xref: PMID:11700955;   PMID:14513374;   PMID:15453262;   PMID:18235848;   PMID:18345010;   PMID:19761212;   PMID:20684594;   PMID:22830992;   PMID:24134630;   PMID:25016371;   PMID:26239395;   PMID:7996554;   PMID:9090611


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4-phenyl-3-furoxancarbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLC mRNA
4-phenyl-3-furoxancarbonitrile analog results in increased expression of GCLC mRNA		 CTD PMID:22851183 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLM mRNA CTD PMID:22851183 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of NQO1 mRNA CTD PMID:22851183 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      chemical role 19479
        donor 18928
          nitric oxide donor 2784
            4-phenyl-3-furoxancarbonitrile 3
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Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteromonocyclic compound 17795
                                    oxadiazole 34
                                      1,2,5-oxadiazole 20
                                        4-phenyl-3-furoxancarbonitrile 3
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