|
G
|
Hsd17b2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
affects binding
|
ISO
|
acetoacetyl CoA binds to HSD17B2 protein
|
CTD |
PMID:25526675 |
|
NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943
|
|
|
G
|
Acly
|
ATP citrate lyase
|
increases abundance affects abundance
|
ISO
|
ACLY protein results in increased abundance of Acetyl Coenzyme A ACLY protein affects the abundance of Acetyl Coenzyme A
|
CTD |
PMID:28077572 PMID:36933457 |
|
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
|
|
G
|
App
|
amyloid beta precursor protein
|
affects localization increases secretion multiple interactions
|
ISO
|
APP protein affects the localization of Acetyl Coenzyme A Acetyl Coenzyme A results in increased secretion of APP protein modified form Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form] IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
|
CTD |
PMID:16122837 PMID:22906069 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
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G
|
Crat
|
carnitine O-acetyltransferase
|
decreases activity
|
EXP
|
Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein
|
CTD |
PMID:8075222 |
|
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:34,073,506...34,087,099
|
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G
|
Ercc6
|
ERCC excision repair 6, chromatin remodeling factor
|
decreases abundance multiple interactions
|
ISO
|
ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A 3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]
|
CTD |
PMID:25440059 |
|
NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
|
|
G
|
G6pc1
|
glucose-6-phosphatase catalytic subunit 1
|
multiple interactions
|
ISO
|
[Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Acetyl Coenzyme A
|
CTD |
PMID:33179799 |
|
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO
|
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
|
CTD |
PMID:16122837 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
G
|
Kat2b
|
lysine acetyltransferase 2B
|
affects binding
|
ISO
|
Acetyl Coenzyme A binds to KAT2B protein
|
CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
|
|
G
|
Metrnl
|
meteorin-like, glial cell differentiation regulator
|
multiple interactions
|
ISO
|
METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A]
|
CTD |
PMID:30213948 |
|
NCBI chr10:107,462,148...107,476,143
Ensembl chr10:107,462,109...107,476,135
|
|
G
|
Nat1
|
N-acetyltransferase 1
|
multiple interactions affects binding
|
ISO
|
[NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein] Acetyl Coenzyme A binds to NAT1 protein
|
CTD |
PMID:20545351 PMID:22835378 |
|
NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
|
|
G
|
Nat2
|
N-acetyltransferase 2
|
multiple interactions
|
ISO
|
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]
|
CTD |
PMID:20545351 |
|
NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304
|
|
G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions
|
ISO
|
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone
|
CTD |
PMID:20545351 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
|
G
|
Echs1
|
enoyl-CoA hydratase, short chain 1
|
increases abundance
|
ISO
|
ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
|
|
G
|
Hibch
|
3-hydroxyisobutyryl-CoA hydrolase
|
increases abundance
|
ISO
|
HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886
|
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
|
G
|
Kat2b
|
lysine acetyltransferase 2B
|
affects binding
|
ISO
|
butyryl-coenzyme A binds to KAT2B protein
|
CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
|
|
|
G
|
Hsdl2
|
hydroxysteroid dehydrogenase like 2
|
multiple interactions
|
ISO
|
[decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein
|
CTD |
PMID:25526675 |
|
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
|
|
G
|
Pecr
|
peroxisomal trans-2-enoyl-CoA reductase
|
multiple interactions
|
ISO
|
[decanoyl-coenzyme A co-treated with NADP] binds to PECR protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
|
|
|
G
|
Acot4
|
acyl-CoA thioesterase 4
|
affects hydrolysis
|
ISO
|
ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A
|
CTD |
PMID:16141203 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
|
|
G
|
Acot8
|
acyl-CoA thioesterase 8
|
affects hydrolysis
|
ISO
|
ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A
|
CTD |
PMID:16141203 |
|
NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:173,950,531...173,962,570
|
|
|
G
|
Pecr
|
peroxisomal trans-2-enoyl-CoA reductase
|
multiple interactions
|
ISO
|
[hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
|
|
|
G
|
Kat2b
|
lysine acetyltransferase 2B
|
affects binding
|
ISO
|
isobutyryl-coenzyme A binds to KAT2B protein
|
CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
|
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
G
|
Hsdl2
|
hydroxysteroid dehydrogenase like 2
|
multiple interactions
|
ISO
|
[lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein
|
CTD |
PMID:25526675 |
|
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
|
|
G
|
Pecr
|
peroxisomal trans-2-enoyl-CoA reductase
|
multiple interactions
|
ISO
|
[lauroyl-coenzyme A co-treated with NADP] binds to PECR protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
|
|
|
G
|
Mlycd
|
malonyl-CoA decarboxylase
|
multiple interactions
|
ISO
|
PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A]
|
CTD |
PMID:14641110 |
|
NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A]
|
CTD |
PMID:14641110 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
|
G
|
Echs1
|
enoyl-CoA hydratase, short chain 1
|
increases abundance
|
ISO
|
ECHS1 gene mutant form results in increased abundance of methacrylyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
|
|
G
|
Hibch
|
3-hydroxyisobutyryl-CoA hydrolase
|
increases abundance
|
ISO
|
HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886
|
|
|
G
|
Dbi
|
diazepam binding inhibitor
|
affects binding
|
ISO
|
S-tetradecanoyl-coenzyme A binds to DBI protein
|
CTD |
PMID:17044054 |
|
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
oleoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
oleoyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
oleoyl-coenzyme A binds to and results in increased activity of PPARG protein
|
CTD |
PMID:11139385 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
|
G
|
Acox1
|
acyl-CoA oxidase 1
|
increases metabolic processing multiple interactions
|
ISO
|
ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A [ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]
|
CTD |
PMID:10497882 |
|
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136
|
|
G
|
Ces1d
|
carboxylesterase 1D
|
increases hydrolysis
|
EXP
|
CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A
|
CTD |
PMID:8611161 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
|
|
G
|
Cpt1a
|
carnitine palmitoyltransferase 1A
|
multiple interactions
|
EXP
|
valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A]
|
CTD |
PMID:19854160 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
|
|
G
|
Dgat1
|
diacylglycerol O-acyltransferase 1
|
multiple interactions
|
ISO
|
DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A]
|
CTD |
PMID:16214399 |
|
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
G
|
Hnf4a
|
hepatocyte nuclear factor 4, alpha
|
decreases expression
|
ISO
|
Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein
|
CTD |
PMID:17992261 |
|
NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
|
CTD |
PMID:11139385 PMID:18812576 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein
|
CTD |
PMID:11139385 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
G
|
Shbg
|
sex hormone binding globulin
|
decreases expression
|
ISO
|
Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein
|
CTD |
PMID:17992261 |
|
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760
|
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
stearoyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
stearoyl-coenzyme A binds to and results in increased activity of PPARG protein
|
CTD |
PMID:11139385 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
|
G
|
Acot4
|
acyl-CoA thioesterase 4
|
affects hydrolysis
|
ISO
|
ACOT4 protein affects the hydrolysis of succinyl-coenzyme A
|
CTD |
PMID:16141203 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
|
|