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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-hydroxy-2-acetamidofluorene
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Accession:CHEBI:17931 term browser browse the term
Definition:A 2-acetamidofluorene that has formula C15H13NO2.
Synonyms:related_synonym: 2-(N-Acetylhydroxylamino)fluorene;   2-(N-Hydroxyacetamido)fluorene;   Fluorenyl-2-acethydroxamic acid;   Hydroxyacetylaminofluorene;   N-(9H-fluoren-2-yl)-N-hydroxyacetamide;   N-Fluoren-2-ylacetohydroxamic acid;   N-Hydroxy-N-acetyl-2-aminofluorene
 alt_id: CHEBI:12511;   CHEBI:12599;   CHEBI:21734;   CHEBI:7294
 xref: CAS:53-95-2
 xref_mesh: MESH:D006881
 xref: kegg.compound:C03954
 chemrof_formula: C15H13NO2
 chemrof_smiles: CC(=O)N(O)c1ccc2c(c1)Cc1ccccc1-2
 chemrof_inchi: InChI=1S/C15H13NO2/c1-10(17)16(18)13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9,18H,8H2,1H3
 chemrof_inchikey: SOKUIEGXJHVFDV-UHFFFAOYSA-N


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N-hydroxy-2-acetamidofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP Hydroxyacetylaminofluorene results in increased expression of ABCB1B mRNA; Hydroxyacetylaminofluorene results in increased expression of ABCB1B protein CTD PMID:22084566 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567 		JBrowse link
G Nat1 N-acetyltransferase 1 decreases activity ISO Hydroxyacetylaminofluorene results in decreased activity of NAT1 protein CTD PMID:19842618 NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527 		JBrowse link
G Nat2 N-acetyltransferase 2 decreases activity ISO Hydroxyacetylaminofluorene results in decreased activity of NAT2 protein CTD PMID:19842618 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases sulfation ISO SULT2A1 protein results in increased sulfation of Hydroxyacetylaminofluorene CTD PMID:10752640 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Tp53 tumor protein p53 increases expression EXP Hydroxyacetylaminofluorene results in increased expression of TP53 protein CTD PMID:9163691 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        xenobiotic 19528
          fluorenes 435
            2-acetamidofluorenes 430
              N-hydroxy-2-acetamidofluorene 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                carbocyclic compound 18739
                                  carbopolycyclic compound 16424
                                    carbotricyclic compound 1601
                                      fluorenes 435
                                        2-acetamidofluorenes 430
                                          N-hydroxy-2-acetamidofluorene 5
paths to the root