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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-hydroxy-2-acetamidofluorene
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Accession:CHEBI:17931 term browser browse the term
Definition:A 2-acetamidofluorene that has formula C15H13NO2.
Synonyms:exact_synonym: N-(9H-fluoren-2-yl)-N-hydroxyacetamide
 related_synonym: 2-(N-Acetylhydroxylamino)fluorene;   2-(N-Hydroxyacetamido)fluorene;   Fluorenyl-2-acethydroxamic acid;   Formula=C15H13NO2;   Hydroxyacetylaminofluorene;   InChI=1S/C15H13NO2/c1-10(17)16(18)13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9,18H,8H2,1H3;   InChIKey=SOKUIEGXJHVFDV-UHFFFAOYSA-N;   N-Fluoren-2-ylacetohydroxamic acid;   N-Hydroxy-N-acetyl-2-aminofluorene;   SMILES=CC(=O)N(O)c1ccc-2c(Cc3ccccc-23)c1
 alt_id: CHEBI:12511;   CHEBI:12599;   CHEBI:21734;   CHEBI:7294
 xref: CAS:53-95-2;   KEGG:C03954
 xref_mesh: MESH:D006881


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N-hydroxy-2-acetamidofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP Hydroxyacetylaminofluorene results in increased expression of ABCB1B mRNA; Hydroxyacetylaminofluorene results in increased expression of ABCB1B protein CTD PMID:22084566 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Nat1 N-acetyltransferase 1 decreases activity ISO Hydroxyacetylaminofluorene results in decreased activity of NAT1 protein CTD PMID:19842618 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 decreases activity ISO Hydroxyacetylaminofluorene results in decreased activity of NAT2 protein CTD PMID:19842618 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases sulfation ISO SULT2A1 protein results in increased sulfation of Hydroxyacetylaminofluorene CTD PMID:10752640 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Hydroxyacetylaminofluorene results in increased expression of TP53 protein CTD PMID:9163691 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        xenobiotic 18722
          fluorenes 428
            2-acetamidofluorenes 423
              N-hydroxy-2-acetamidofluorene 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            organic hydride 18687
                              organic fundamental parent 18687
                                hydrocarbon 18438
                                  cyclic hydrocarbon 17231
                                    arene 17212
                                      polycyclic arene 17037
                                        ortho-fused polycyclic arene 9836
                                          fluorene 557
                                            fluorenes 428
                                              2-acetamidofluorenes 423
                                                N-hydroxy-2-acetamidofluorene 5
paths to the root