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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Aciculatin
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Accession:CHEBI:179276 term browser browse the term
Synonyms:exact_synonym: 8-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one
 related_synonym: Formula=C22H22O8;   InChI=1S/C22H22O8/c1-10-21(27)15(26)9-18(29-10)20-17(28-2)8-14(25)19-13(24)7-16(30-22(19)20)11-3-5-12(23)6-4-11/h3-8,10,15,18,21,23,25-27H,9H2,1-2H3/t10-,15+,18+,21-/m1/s1;   InChIKey=RUTGHCUXABPJTJ-VAXHSPNUSA-N;   SMILES=O1[C@@](C[C@H](O)[C@H](O)[C@H]1C)(C=2C=3OC(=CC(=O)C3C(O)=CC2OC)C4=CC=C(O)C=C4)[H]
 xref: CAS:134044-97-6;   Chemspider:116365
 xref_mesh: MESH:C074400



show annotations for term's descendants           Sort by:
Aciculatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP2K4 mitogen-activated protein kinase kinase 4 multiple interactions ISO aciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAP2K4 protein] CTD PMID:21548916 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO aciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21548916 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO aciculatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:21548916 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO aciculatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; aciculatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21548916 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO aciculatin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; aciculatin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21548916 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO aciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of RELA protein] CTD PMID:21548916 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26503
    chemical entity 26483
      atom 26479
        nonmetal atom 25741
          oxygen atom 24932
            oxygen molecular entity 24932
              flavonoids 12304
                Aciculatin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 26503
    subatomic particle 26479
      composite particle 26479
        hadron 26479
          baryon 26479
            nucleon 26479
              atomic nucleus 26479
                atom 26479
                  main group element atom 26216
                    p-block element atom 26216
                      carbon group element atom 25661
                        carbon atom 25623
                          organic molecular entity 25623
                            heteroorganic entity 25006
                              organochalcogen compound 24600
                                organooxygen compound 24194
                                  carbohydrates and carbohydrate derivatives 16821
                                    carbohydrate 16821
                                      carbohydrate derivative 15687
                                        glycosyl compound 13759
                                          C-glycosyl compound 326
                                            Aciculatin 6
paths to the root