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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sotorasib
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Accession:CHEBI:178199 term browser browse the term
Definition:A pyridopyrimidine that is pyrido[2,3-d]pyrimidin-2(1H)-one substituted by 4-methyl-2-(propan-2-yl)pyridin-3-yl, (2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl, fluoro and 2-fluoro-6-hydroxyphenyl groups at positions 1, 4, 6 and 7, respectively. It is approved for the treatment of patients with non-small cell lung cancer having KRASG12C mutations.
Synonyms:related_synonym: 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one;   AMG-510;   AMG510;   Lumakras;   sotorasibum
 xref: CAS:2296729-00-3;   Chemspider:72380148;   DrugBank:DB15569
 xref_mesh: MESH:C000706028
 xref: kegg.drug:D12055;   pubmed:31189530;   pubmed:31666701;   pubmed:31820981;   pubmed:32540954;   pubmed:32686745;   pubmed:32955176;   pubmed:33283304;   pubmed:33466360;   pubmed:33547148;   pubmed:33957355;   pubmed:33971321;   pubmed:34004237;   pubmed:34043291;   pubmed:34094546;   pubmed:34096690;   pubmed:34137282;   pubmed:34140669;   pubmed:34144959;   pubmed:34158284;   pubmed:34219153;   pubmed:34301758;   pubmed:34357500;   pubmed:34359807;   wikipedia.en:Sotorasib
 chemrof_formula: C30H30F2N6O3
 chemrof_smiles: C=CC(=O)N1CCN(c2nc(=O)n(-c3c(C)ccnc3C(C)C)c3nc(-c4c(O)cccc4F)c(F)cc23)[C@@H](C)C1
 chemrof_inchi: InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
 chemrof_inchikey: NXQKSXLFSAEQCZ-SFHVURJKSA-N



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sotorasib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AADAT mRNA CTD PMID:36139627 NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540
JBrowse link
G Abhd11 abhydrolase domain containing 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ABHD11 mRNA CTD PMID:36139627 NCBI chr12:27,318,739...27,322,016
Ensembl chr12:27,318,749...27,321,970
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACHE mRNA CTD PMID:36139627 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Acp7 acid phosphatase 7, tartrate resistant multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACP7 mRNA CTD PMID:36139627 NCBI chr 1:93,022,801...93,048,484
Ensembl chr 1:93,024,991...93,048,873
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACSL5 mRNA CTD PMID:36139627 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACSM3 mRNA CTD PMID:36139627 NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACTA2 mRNA CTD PMID:36139627 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Actbl2 actin, beta-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACTBL2 mRNA CTD PMID:36139627 NCBI chr 2:44,591,391...44,594,138
Ensembl chr 2:44,591,391...44,594,138
JBrowse link
G Acy3 aminoacylase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACY3 mRNA CTD PMID:36139627 NCBI chr 1:210,709,238...210,715,258
Ensembl chr 1:210,709,294...210,715,633
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADAMTS1 mRNA CTD PMID:36139627 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
JBrowse link
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADAMTS16 mRNA CTD PMID:36139627 NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:34,258,899...34,388,952
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADAMTS4 mRNA CTD PMID:36139627 NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514
JBrowse link
G Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ADAMTS6 mRNA CTD PMID:36139627 NCBI chr 2:37,155,260...37,367,077
Ensembl chr 2:37,155,288...37,367,070
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADGRG1 mRNA CTD PMID:36139627 NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,010,031...10,047,124
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ADGRL3 mRNA CTD PMID:36139627 NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADRB2 mRNA CTD PMID:36139627 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
JBrowse link
G Afap1l1 actin filament associated protein 1-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AFAP1L1 mRNA CTD PMID:36139627 NCBI chr18:57,454,120...57,514,584
Ensembl chr18:57,454,121...57,514,480
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AGR2 mRNA CTD PMID:36139627 NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677
JBrowse link
G Akap5 A-kinase anchoring protein 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AKAP5 mRNA CTD PMID:36139627 NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620
JBrowse link
G Akna AT-hook transcription factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AKNA mRNA CTD PMID:36139627 NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528
JBrowse link
G Akt3 AKT serine/threonine kinase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AKT3 mRNA CTD PMID:36139627 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ALDH1A2 mRNA CTD PMID:36139627 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ALDOC mRNA CTD PMID:36139627 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
JBrowse link
G Aloxe3 arachidonate epidermal lipoxygenase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ALOXE3 mRNA CTD PMID:36139627 NCBI chr10:54,329,224...54,353,167
Ensembl chr10:54,329,043...54,353,166
JBrowse link
G Alpg alkaline phosphatase, germ cell multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ALPG mRNA CTD PMID:36139627 NCBI chr 9:95,187,995...95,205,127
Ensembl chr 9:95,198,334...95,205,742
JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AMN1 mRNA CTD PMID:36139627 NCBI chr 4:183,886,469...183,913,411
Ensembl chr 4:183,886,474...183,913,411
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AMPD3 mRNA CTD PMID:36139627 NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608
JBrowse link
G Ang angiogenin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANG mRNA CTD PMID:36139627 NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANGPTL4 mRNA CTD PMID:36139627 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
JBrowse link
G Ank3 ankyrin 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANK3 mRNA CTD PMID:36139627 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
JBrowse link
G Ankef1 ankyrin repeat and EF-hand domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ANKEF1 mRNA CTD PMID:36139627 NCBI chr 3:144,300,500...144,335,759
Ensembl chr 3:144,300,529...144,335,753
JBrowse link
G Ankrd2 ankyrin repeat domain 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ANKRD2 mRNA CTD PMID:36139627 NCBI chr 1:250,796,419...250,805,867
Ensembl chr 1:250,796,409...250,805,870
JBrowse link
G Ankrd24 ankyrin repeat domain 24 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANKRD24 mRNA CTD PMID:36139627 NCBI chr 7:8,712,720...8,731,910
Ensembl chr 7:8,712,722...8,731,910
JBrowse link
G Ankrd37 ankyrin repeat domain 37 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANKRD37 mRNA CTD PMID:36139627 NCBI chr16:53,001,487...53,004,545
Ensembl chr16:52,994,740...53,004,545
JBrowse link
G Ankrd65 ankyrin repeat domain 65 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ANKRD65 mRNA CTD PMID:36139627 NCBI chr 5:171,680,597...171,682,854
Ensembl chr 5:171,680,597...171,683,431
JBrowse link
G Ano7 anoctamin 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANO7 mRNA CTD PMID:36139627 NCBI chr 9:101,364,915...101,392,711
Ensembl chr 9:101,364,842...101,394,173
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANPEP mRNA CTD PMID:36139627 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AOC3 mRNA CTD PMID:36139627 NCBI chr10:86,773,018...86,780,961 JBrowse link
G Apln apelin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of APLN mRNA CTD PMID:36139627 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:132,081,759...132,091,246
JBrowse link
G Apobr apolipoprotein B receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of APOBR mRNA CTD PMID:36139627 NCBI chr 1:190,599,595...190,603,782
Ensembl chr 1:190,597,638...190,616,809
JBrowse link
G Arfgef3 ARFGEF family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARFGEF3 mRNA CTD PMID:36139627 NCBI chr 1:15,058,574...15,223,742
Ensembl chr 1:15,058,579...15,223,742
JBrowse link
G Arhgap31 Rho GTPase activating protein 31 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARHGAP31 mRNA CTD PMID:36139627 NCBI chr11:75,544,176...75,657,087
Ensembl chr11:75,544,040...75,661,076
JBrowse link
G Arhgap8 Rho GTPase activating protein 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARHGAP8 mRNA CTD PMID:36139627 NCBI chr 7:117,723,512...117,782,031
Ensembl chr 7:117,730,578...117,782,030
JBrowse link
G Armh1 armadillo-like helical domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ARMH1 mRNA CTD PMID:36139627 NCBI chr 5:135,919,057...135,958,653
Ensembl chr 5:135,919,057...135,958,626
JBrowse link
G Atg9b autophagy related 9B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATG9B mRNA CTD PMID:36139627 NCBI chr 4:11,678,548...11,686,097
Ensembl chr 4:11,678,299...11,686,079
JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ATP10D mRNA CTD PMID:36139627 NCBI chr14:36,265,696...36,366,460
Ensembl chr14:36,265,696...36,366,460
JBrowse link
G Atp13a3 ATPase 13A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATP13A3 mRNA CTD PMID:36139627 NCBI chr11:83,860,725...83,946,899
Ensembl chr11:83,870,218...83,944,662
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATP2A3 mRNA CTD PMID:36139627 NCBI chr10:58,079,710...58,111,279
Ensembl chr10:58,079,852...58,111,278
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATP6V0D2 mRNA CTD PMID:36139627 NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245
JBrowse link
G Avil advillin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AVIL mRNA CTD PMID:36139627 NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436
JBrowse link
G Bach2 BTB domain and CNC homolog 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BACH2 mRNA CTD PMID:36139627 NCBI chr 5:51,428,802...51,779,030
Ensembl chr 5:51,434,870...51,774,234
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BAMBI mRNA CTD PMID:36139627 NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247
JBrowse link
G Barx2 BARX homeobox 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BARX2 mRNA CTD PMID:36139627 NCBI chr 8:38,509,277...38,576,978
Ensembl chr 8:38,509,277...38,576,978
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BATF3 mRNA CTD PMID:36139627 NCBI chr13:105,220,782...105,232,365
Ensembl chr13:105,220,390...105,232,369
JBrowse link
G Bcl2l14 Bcl2-like 14 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BCL2L14 mRNA CTD PMID:36139627 NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079
JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BCO2 mRNA CTD PMID:36139627 NCBI chr 8:59,778,571...59,803,597
Ensembl chr 8:59,778,575...59,799,168
JBrowse link
G Bex1 brain expressed X-linked 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BEX2 mRNA CTD PMID:36139627 NCBI chr  X:104,010,639...104,012,143
Ensembl chr  X:104,010,371...104,011,236
JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BICDL2 mRNA CTD PMID:36139627 NCBI chr10:13,196,205...13,204,642
Ensembl chr10:13,195,913...13,204,642
JBrowse link
G Bin2 bridging integrator 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BIN2 mRNA CTD PMID:36139627 NCBI chr 7:133,620,782...133,647,019
Ensembl chr 7:133,620,140...133,647,218
JBrowse link
G Blacat1 BLACAT1 overlapping LEMD1 locus multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BLACAT1 mRNA CTD PMID:36139627 NCBI chr13:46,189,091...46,202,506
Ensembl chr13:46,197,208...46,197,306
JBrowse link
G Blnk B-cell linker multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BLNK mRNA CTD PMID:36139627 NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:249,703,072...249,770,533
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BMP6 mRNA CTD PMID:36139627 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261
JBrowse link
G Borcs8 BLOC-1 related complex subunit 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BORCS8 mRNA CTD PMID:36139627 NCBI chr16:19,308,247...19,314,910
Ensembl chr16:19,308,247...19,314,963
JBrowse link
G Btc betacellulin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BTC mRNA CTD PMID:36139627 NCBI chr14:16,992,668...17,031,178
Ensembl chr14:16,992,193...17,033,078
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BTG2 mRNA CTD PMID:36139627 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
JBrowse link
G C13h1orf116 similar to human chromosome 1 open reading frame 116 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of C1ORF116 mRNA CTD PMID:36139627 NCBI chr13:44,739,716...44,753,695
Ensembl chr13:44,727,092...44,754,009
JBrowse link
G C14h7orf57 similar to human chromosome 7 open reading frame 57 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of C7ORF57 mRNA CTD PMID:36139627 NCBI chr14:87,962,231...87,982,043
Ensembl chr14:87,959,540...87,982,040
JBrowse link
G C1h6orf118 similar to human chromosome 6 open reading frame 118 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C6ORF118 mRNA CTD PMID:36139627 NCBI chr 1:54,287,934...54,311,640
Ensembl chr 1:54,287,936...54,311,847
JBrowse link
G C1r complement C1r multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C1R mRNA CTD PMID:36139627 NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714
JBrowse link
G C1s complement C1s multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C1S mRNA CTD PMID:36139627 NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COXFA4L3 mRNA CTD PMID:36139627 NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:130,173,416...130,177,089
JBrowse link
G C7 complement C7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C7 mRNA CTD PMID:36139627 NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CA9 mRNA CTD PMID:36139627 NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CACNA1D mRNA CTD PMID:36139627 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CACNA1F mRNA CTD PMID:36139627 NCBI chr  X:17,539,992...17,568,308
Ensembl chr  X:17,539,920...17,568,308
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CACNB4 mRNA CTD PMID:36139627 NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:57,315,900...57,578,220
JBrowse link
G Calb2 calbindin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CALB2 mRNA CTD PMID:36139627 NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952
JBrowse link
G Capn12 calpain 12 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CAPN12 mRNA CTD PMID:36139627 NCBI chr 1:93,298,571...93,311,220
Ensembl chr 1:93,298,571...93,310,630
JBrowse link
G Capn8 calpain 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CAPN8 mRNA CTD PMID:36139627 NCBI chr13:96,783,640...96,847,825
Ensembl chr13:96,783,667...96,847,820
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CASP1 mRNA CTD PMID:36139627 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
JBrowse link
G Casp3 caspase 3 increases cleavage ISO sotorasib results in increased cleavage of CASP3 protein CTD PMID:31666701 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Catspere catsper channel auxiliary subunit epsilon multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CATSPERE mRNA CTD PMID:36139627 NCBI chr13:92,331,826...92,487,215
Ensembl chr13:92,351,281...92,483,149
JBrowse link
G Ccdc110 coiled-coil domain containing 110 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCDC110 mRNA CTD PMID:36139627 NCBI chr16:53,048,305...53,069,606
Ensembl chr16:53,047,965...53,069,777
JBrowse link
G Ccdc87 coiled-coil domain containing 87 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCDC87 mRNA CTD PMID:36139627 NCBI chr 1:211,564,419...211,567,115
Ensembl chr 1:211,475,789...211,568,008
JBrowse link
G Ccdc89 coiled-coil domain containing 89 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCDC89 mRNA CTD PMID:36139627 NCBI chr 1:153,798,786...153,800,048
Ensembl chr 1:153,797,440...153,803,002
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCL22 mRNA CTD PMID:36139627 NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359
JBrowse link
G Ccm2l CCM2 like scaffold protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCM2L mRNA CTD PMID:36139627 NCBI chr 3:161,993,717...162,009,372
Ensembl chr 3:161,859,312...162,009,371
JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCNE2 mRNA CTD PMID:36139627 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCR1 mRNA CTD PMID:36139627 NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
JBrowse link
G Cd22 CD22 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CD22 mRNA CTD PMID:36139627 NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:95,244,868...95,259,730
JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CD274 mRNA CTD PMID:36139627 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951
JBrowse link
G Cd72 Cd72 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CD72 mRNA CTD PMID:36139627 NCBI chr 5:62,493,155...62,500,779
Ensembl chr 5:62,493,161...62,500,519
JBrowse link
G Cd74 CD74 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CD74 mRNA CTD PMID:36139627 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410
JBrowse link
G Cd82 Cd82 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CD82 mRNA CTD PMID:36139627 NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:99,842,757...99,886,744
JBrowse link
G Cdcp1 CUB domain containing protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDCP1 mRNA CTD PMID:36139627 NCBI chr 8:131,706,140...131,742,799
Ensembl chr 8:131,706,140...131,742,877
JBrowse link
G Cdh15 cadherin 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDH15 mRNA CTD PMID:36139627 NCBI chr19:67,812,169...67,834,986
Ensembl chr19:67,812,164...67,834,985
JBrowse link
G Cdh3 cadherin 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDH3 mRNA CTD PMID:36139627 NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CDKN1A mRNA CTD PMID:36139627 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDKN1C mRNA CTD PMID:36139627 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
JBrowse link
G Cenps centromere protein S multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CENPS mRNA CTD PMID:36139627 NCBI chr 5:164,847,009...164,856,705 JBrowse link
G Cfap184 cilia and flagella associated protein 184 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CFAP184 mRNA CTD PMID:36139627 NCBI chr14:78,501,256...78,503,715
Ensembl chr14:78,486,414...78,507,808
JBrowse link
G Cfap45 cilia and flagella associated protein 45 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CFAP45 mRNA CTD PMID:36139627 NCBI chr13:87,521,831...87,545,236
Ensembl chr13:87,521,518...87,545,234
JBrowse link
G Cfap92 cilia and flagella associated protein 92 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CFAP92 mRNA CTD PMID:36139627 NCBI chr 4:121,683,889...121,738,920
Ensembl chr 4:121,683,889...121,737,802
JBrowse link
G Cfap96 cilia and flagella associated protein 96 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CFAP96 mRNA CTD PMID:36139627 NCBI chr16:53,023,623...53,048,176
Ensembl chr16:53,023,878...53,048,965
JBrowse link
G Cfh complement factor H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CFH mRNA CTD PMID:36139627 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CHD7 mRNA CTD PMID:36139627 NCBI chr 5:26,609,245...26,792,736
Ensembl chr 5:26,609,407...26,792,734
JBrowse link
G Chd9nb CHD9 neighbor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHD9NB mRNA CTD PMID:36139627 NCBI chr19:32,348,739...32,350,224 JBrowse link
G Chgb chromogranin B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHGB mRNA CTD PMID:36139627 NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CHRM4 mRNA CTD PMID:36139627 NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771
JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHRNA10 mRNA CTD PMID:36139627 NCBI chr 1:165,898,932...165,905,348
Ensembl chr 1:165,899,261...165,903,458
JBrowse link
G Ciart circadian associated repressor of transcription multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CIART mRNA CTD PMID:36139627 NCBI chr 2:186,108,744...186,113,778
Ensembl chr 2:186,108,752...186,112,246
JBrowse link
G Cimip2a ciliary microtubule inner protein 2A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CIMIP2A mRNA CTD PMID:36139627 NCBI chr 3:28,429,413...28,437,210
Ensembl chr 3:28,431,410...28,436,125
JBrowse link
G Cldn9 claudin 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CLDN9 mRNA CTD PMID:36139627 NCBI chr10:13,218,728...13,220,159
Ensembl chr10:13,218,729...13,220,178
JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CNIH2 mRNA CTD PMID:36139627 NCBI chr 1:211,828,791...211,834,474
Ensembl chr 1:211,828,794...211,834,437
JBrowse link
G Col13a1 collagen type XIII alpha 1 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of COL13A1 mRNA CTD PMID:36139627 NCBI chr20:30,326,744...30,466,800
Ensembl chr20:30,326,744...30,466,800
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COL1A2 mRNA CTD PMID:36139627 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
JBrowse link
G Col5a3 collagen type V alpha 3 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COL5A3 mRNA CTD PMID:36139627 NCBI chr 8:27,580,768...27,626,002
Ensembl chr 8:27,580,768...27,626,122
JBrowse link
G Col6a3 collagen type VI alpha 3 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of COL6A3 mRNA CTD PMID:36139627 NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990
JBrowse link
G Col9a2 collagen type IX alpha 2 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COL9A2 mRNA CTD PMID:36139627 NCBI chr 5:139,892,798...139,910,131
Ensembl chr 5:139,892,798...139,909,855
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COLQ mRNA CTD PMID:36139627 NCBI chr16:6,738,251...6,830,492
Ensembl chr16:6,738,251...6,793,501
JBrowse link
G Cpe carboxypeptidase E multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CPE mRNA CTD PMID:36139627 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524
JBrowse link
G Cracr2b calcium release activated channel regulator 2B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CRACR2B mRNA CTD PMID:36139627 NCBI chr 1:205,987,957...205,993,515
Ensembl chr 1:205,990,507...205,993,516
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CREB3L1 mRNA CTD PMID:36139627 NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:98,408,058...98,449,104
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CREB3L3 mRNA CTD PMID:36139627 NCBI chr 7:9,273,320...9,281,755
Ensembl chr 7:9,273,338...9,281,778
JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CREG2 mRNA CTD PMID:36139627 NCBI chr 9:49,367,693...49,441,133
Ensembl chr 9:49,399,114...49,440,985
JBrowse link
G Crybg1 crystallin beta-gamma domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CRYBG1 mRNA CTD PMID:36139627 NCBI chr20:49,007,673...49,204,040
Ensembl chr20:49,007,929...49,204,047
JBrowse link
G Crym crystallin, mu multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CRYM mRNA CTD PMID:36139627 NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:183,991,745...184,006,962
JBrowse link
G Csad cysteine sulfinic acid decarboxylase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CSAD mRNA CTD PMID:36139627 NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CSF3 mRNA CTD PMID:36139627 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860
JBrowse link
G Ctsc cathepsin C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CTSC mRNA CTD PMID:36139627 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CTSL mRNA CTD PMID:36139627 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
JBrowse link
G Ctso cathepsin O multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CTSO mRNA CTD PMID:36139627 NCBI chr 2:169,528,468...169,551,975
Ensembl chr 2:169,528,511...169,554,995
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CX3CL1 mRNA CTD PMID:36139627 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO sotorasib results in increased expression of CXCL10 mRNA CTD PMID:31666701 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO sotorasib results in increased expression of CXCL11 mRNA CTD PMID:31666701 NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CYP26B1 mRNA CTD PMID:36139627 NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DDIT4L mRNA CTD PMID:36139627 NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
JBrowse link
G Ddx60 DEXD/H-box helicase 60 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DDX60 mRNA CTD PMID:36139627 NCBI chr16:33,087,940...33,208,843
Ensembl chr16:33,087,988...33,208,839
JBrowse link
G Dennd3 DENN domain containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DENND3 mRNA CTD PMID:36139627 NCBI chr 7:107,304,860...107,362,573
Ensembl chr 7:107,220,192...107,362,573
JBrowse link
G Depp1 DEPP autophagy regulator 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DEPP1 mRNA CTD PMID:36139627 NCBI chr 4:151,583,105...151,585,455
Ensembl chr 4:151,581,502...151,586,233
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DEPTOR mRNA CTD PMID:36139627 NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DHRS2 mRNA CTD PMID:36139627 NCBI chr15:32,658,855...32,673,591
Ensembl chr15:32,659,223...32,673,588
JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DIO2 mRNA CTD PMID:36139627 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DKK3 mRNA CTD PMID:36139627 NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DLC1 mRNA CTD PMID:36139627 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819
JBrowse link
G Dmkn dermokine multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DMKN mRNA CTD PMID:36139627 NCBI chr 1:95,140,737...95,158,676
Ensembl chr 1:95,141,620...95,157,439
JBrowse link
G Dnaaf8 dynein axonemal assembly factor 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DNAAF8 mRNA CTD PMID:36139627 NCBI chr10:11,107,988...11,121,475
Ensembl chr10:11,107,404...11,121,345
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DNAH11 mRNA CTD PMID:36139627 NCBI chr 6:144,982,130...145,298,523
Ensembl chr 6:144,973,797...145,298,692
JBrowse link
G Doc2b double C2 domain beta multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DOC2B mRNA CTD PMID:36139627 NCBI chr10:61,126,295...61,151,533
Ensembl chr10:61,126,295...61,151,533
JBrowse link
G Dok3 docking protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DOK3 mRNA CTD PMID:36139627 NCBI chr17:9,114,763...9,121,781
Ensembl chr17:9,114,762...9,120,335
JBrowse link
G Drc3 dynein regulatory complex subunit 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DRC3 mRNA CTD PMID:36139627 NCBI chr10:45,620,045...45,698,902
Ensembl chr10:45,648,410...45,698,900
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DUOX1 mRNA CTD PMID:36139627 NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUOX2 mRNA CTD PMID:36139627 NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203
JBrowse link
G Duoxa1 dual oxidase maturation factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUOXA1 mRNA CTD PMID:36139627 NCBI chr 3:129,703,416...129,714,110
Ensembl chr 3:129,703,416...129,706,829
JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUSP4 mRNA CTD PMID:36139627 NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUSP5 mRNA CTD PMID:36139627 NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUSP6 mRNA CTD PMID:36139627 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
JBrowse link
G E2f2 E2F transcription factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of E2F2 mRNA CTD PMID:36139627 NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:153,682,789...153,706,087
JBrowse link
G E2f7 E2F transcription factor 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of E2F7 mRNA CTD PMID:36139627 NCBI chr 7:48,036,881...48,079,055
Ensembl chr 7:48,037,749...48,079,055
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EFEMP2 mRNA CTD PMID:36139627 NCBI chr 1:212,211,057...212,218,739
Ensembl chr 1:212,210,972...212,218,739
JBrowse link
G Efna3 ephrin A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EFNA3 mRNA CTD PMID:36139627 NCBI chr 2:177,026,928...177,035,838
Ensembl chr 2:177,026,933...177,044,843
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of EGF mRNA CTD PMID:36139627 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation ISO sotorasib results in increased phosphorylation of EGFR protein CTD PMID:31666701 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Eif4e3 eukaryotic translation initiation factor 4E family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EIF4E3 mRNA CTD PMID:36139627 NCBI chr 4:133,709,802...133,858,398
Ensembl chr 4:133,625,768...133,885,647
JBrowse link
G Elf5 E74 like ETS transcription factor 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ELF5 mRNA CTD PMID:36139627 NCBI chr 3:110,264,460...110,291,926
Ensembl chr 3:110,252,797...110,291,926
JBrowse link
G Elmod1 ELMO domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ELMOD1 mRNA CTD PMID:36139627 NCBI chr 8:63,194,539...63,251,526
Ensembl chr 8:63,137,295...63,251,322
JBrowse link
G Eno2 enolase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ENO2 mRNA CTD PMID:36139627 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220
JBrowse link
G Eno4 enolase 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ENO4 mRNA CTD PMID:36139627 NCBI chr 1:268,073,318...268,113,494
Ensembl chr 1:268,082,522...268,106,300
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ENPP1 mRNA CTD PMID:36139627 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ENTPD2 mRNA CTD PMID:36139627 NCBI chr 3:28,611,722...28,617,237
Ensembl chr 3:28,611,772...28,618,184
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPAS1 mRNA CTD PMID:36139627 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPHA3 mRNA CTD PMID:36139627 NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425
JBrowse link
G Epha8 Eph receptor A8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPHA8 mRNA CTD PMID:36139627 NCBI chr 5:154,449,566...154,476,966
Ensembl chr 5:154,449,566...154,476,966
JBrowse link
G Eppk1 epiplakin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPPK1 mRNA CTD PMID:36139627 NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ERAP1 mRNA CTD PMID:36139627 NCBI chr 2:5,666,337...5,705,256
Ensembl chr 2:5,666,436...5,740,056
JBrowse link
G Erfl ETS repressor factor like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ERFL mRNA CTD PMID:36139627 NCBI chr 1:89,649,244...89,654,379
Ensembl chr 1:89,649,303...89,665,872
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ERO1A mRNA CTD PMID:36139627 NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ESRP1 mRNA CTD PMID:36139627 NCBI chr 5:29,224,831...29,279,381
Ensembl chr 5:29,225,360...29,279,278
JBrowse link
G Etv2 ETS variant transcription factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ETV2 mRNA CTD PMID:36139627 NCBI chr 1:95,017,980...95,021,582
Ensembl chr 1:95,017,687...95,021,457
JBrowse link
G Etv4 ETS variant transcription factor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ETV4 mRNA CTD PMID:36139627 NCBI chr10:87,206,977...87,222,202
Ensembl chr10:87,206,977...87,222,318
JBrowse link
G Evi2a ecotropic viral integration site 2A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EVI2A mRNA CTD PMID:36139627 NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516
JBrowse link
G Exoc3l1 exocyst complex component 3-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of EXOC3L1 mRNA CTD PMID:36139627 NCBI chr19:50,076,761...50,084,278
Ensembl chr19:50,076,266...50,082,422
JBrowse link
G Exoc3l4 exocyst complex component 3-like 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of EXOC3L4 mRNA CTD PMID:36139627 NCBI chr 6:136,273,857...136,287,877
Ensembl chr 6:136,273,854...136,287,881
JBrowse link
G Exph5 exophilin 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EXPH5 mRNA CTD PMID:36139627 NCBI chr 8:62,595,116...62,671,575
Ensembl chr 8:62,595,116...62,671,575
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of F2RL1 mRNA CTD PMID:36139627 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954
JBrowse link
G Fam107b family with sequence similarity 107, member B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FAM107B mRNA CTD PMID:36139627 NCBI chr17:79,387,795...79,594,165
Ensembl chr17:79,387,795...79,594,288
JBrowse link
G Fam186b family with sequence similarity 186, member B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FAM186B mRNA CTD PMID:36139627 NCBI chr 7:132,287,686...132,303,188
Ensembl chr 7:132,287,692...132,303,123
JBrowse link
G Fam241a family with sequence similarity 241 member A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FAM241A mRNA CTD PMID:36139627 NCBI chr 2:219,019,025...219,049,648
Ensembl chr 2:219,018,241...219,049,770
JBrowse link
G Fat2 FAT atypical cadherin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FAT2 mRNA CTD PMID:36139627 NCBI chr10:39,864,765...39,957,027
Ensembl chr10:39,864,766...39,956,902
JBrowse link
G Fbxo36 F-box protein 36 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FBXO36 mRNA CTD PMID:36139627 NCBI chr 9:93,490,618...93,555,298
Ensembl chr 9:93,489,865...93,555,305
JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FDXR mRNA CTD PMID:36139627 NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542
JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FGF19 mRNA CTD PMID:36139627 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267
JBrowse link
G Fhip1a FHF complex subunit HOOK interacting protein 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FHIP1A mRNA CTD PMID:36139627 NCBI chr 2:173,319,252...173,489,514
Ensembl chr 2:173,319,257...173,453,902
JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FLACC1 mRNA CTD PMID:36139627 NCBI chr 9:67,809,731...67,837,793
Ensembl chr 9:67,809,739...67,837,793
JBrowse link
G Flnc filamin C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FLNC mRNA CTD PMID:36139627 NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,999,547...59,027,240
JBrowse link
G Fmn1 formin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FMN1 mRNA CTD PMID:36139627 NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:120,555,431...120,933,124
JBrowse link
G Fndc11 fibronectin type III domain containing 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FNDC11 mRNA CTD PMID:36139627 NCBI chr 3:188,708,045...188,710,670
Ensembl chr 3:188,707,334...188,714,164
JBrowse link
G Foxd4 forkhead box D4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FOXD4 mRNA CTD PMID:36139627 NCBI chr 1:231,983,872...231,985,565 JBrowse link
G Foxq1 forkhead box Q1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FOXQ1 mRNA CTD PMID:36139627 NCBI chr17:33,121,454...33,124,087
Ensembl chr17:33,121,545...33,123,720
JBrowse link
G Frmd4b FERM domain containing 4B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FRMD4B mRNA CTD PMID:36139627 NCBI chr 4:131,452,361...131,778,734
Ensembl chr 4:131,452,365...131,640,287
JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FSCN1 mRNA CTD PMID:36139627 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734
JBrowse link
G Fut11 fucosyltransferase 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POFUT4 mRNA CTD PMID:36139627 NCBI chr15:3,648,022...3,651,582
Ensembl chr15:3,643,009...3,651,610
JBrowse link
G Fyb2 FYN binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FYB2 mRNA CTD PMID:36139627 NCBI chr 5:124,906,005...125,029,867
Ensembl chr 5:124,905,982...125,029,865
JBrowse link
G Gab2 GRB2-associated binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAB2 mRNA CTD PMID:36139627 NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:160,841,066...161,036,940
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAD1 mRNA CTD PMID:36139627 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAL3ST1 mRNA CTD PMID:36139627 NCBI chr14:83,094,265...83,109,992
Ensembl chr14:83,094,385...83,109,978
JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GALNT7 mRNA CTD PMID:36139627 NCBI chr16:37,589,368...37,713,911
Ensembl chr16:37,589,425...37,713,909
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GAS6 mRNA CTD PMID:36139627 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
JBrowse link
G Gask1b golgi associated kinase 1B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GASK1B mRNA CTD PMID:36139627 NCBI chr 2:167,345,738...167,410,606
Ensembl chr 2:167,345,809...167,410,603
JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GBP2 mRNA CTD PMID:36139627 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810
JBrowse link
G Gckr glucokinase regulator multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GCKR mRNA CTD PMID:36139627 NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GCNT3 mRNA CTD PMID:36139627 NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:79,566,753...79,581,595
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GDAP1 mRNA CTD PMID:36139627 NCBI chr 5:6,715,935...6,735,013
Ensembl chr 5:6,715,935...6,735,313
JBrowse link
G Ghr growth hormone receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GHR mRNA CTD PMID:36139627 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
JBrowse link
G Gipc3 GIPC PDZ domain containing family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GIPC3 mRNA CTD PMID:36139627 NCBI chr 7:9,026,905...9,034,005
Ensembl chr 7:9,026,905...9,034,795
JBrowse link
G Gipr gastric inhibitory polypeptide receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GIPR mRNA CTD PMID:36139627 NCBI chr 1:87,932,316...87,956,084
Ensembl chr 1:87,932,623...87,942,492
JBrowse link
G Gjb3 gap junction protein, beta 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GJB3 mRNA CTD PMID:36139627 NCBI chr 5:144,933,692...144,939,435
Ensembl chr 5:144,933,696...144,940,280
JBrowse link
G Gjb4 gap junction protein, beta 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GJB4 mRNA CTD PMID:36139627 NCBI chr 5:144,948,231...144,964,014
Ensembl chr 5:144,951,184...144,964,097
JBrowse link
G Gldc glycine decarboxylase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GLDC mRNA CTD PMID:36139627 NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GLUL mRNA CTD PMID:36139627 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GPNMB mRNA CTD PMID:36139627 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
JBrowse link
G Gpr146 G protein-coupled receptor 146 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GPR146 mRNA CTD PMID:36139627 NCBI chr12:20,365,790...20,381,122
Ensembl chr12:20,364,269...20,381,345
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GPR37L1 mRNA CTD PMID:36139627 NCBI chr13:49,150,355...49,157,204
Ensembl chr13:49,150,359...49,157,204
JBrowse link
G Gpr39 G protein-coupled receptor 39 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GPR39 mRNA CTD PMID:36139627 NCBI chr13:39,667,908...39,879,944
Ensembl chr13:39,667,909...39,880,902
JBrowse link
G Gpr87 G protein-coupled receptor 87 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GPR87 mRNA CTD PMID:36139627 NCBI chr 2:145,589,630...145,608,094
Ensembl chr 2:145,589,569...145,604,442
JBrowse link
G Gramd1b GRAM domain containing 1B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GRAMD1B mRNA CTD PMID:36139627 NCBI chr 8:49,551,642...49,790,965
Ensembl chr 8:49,556,332...49,791,052
JBrowse link
G Grb7 growth factor receptor bound protein 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GRB7 mRNA CTD PMID:36139627 NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,939,299...83,949,382
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GRIN2D mRNA CTD PMID:36139627 NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:105,444,813...105,481,236
JBrowse link
G Gsdmc gasdermin C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GSDMC mRNA CTD PMID:36139627 NCBI chr 7:97,482,713...97,509,985
Ensembl chr 7:97,483,257...97,499,587
JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GTF2IRD2 mRNA CTD PMID:36139627 NCBI chr12:28,134,199...28,179,089
Ensembl chr12:28,133,792...28,172,876
JBrowse link
G Guca1b guanylate cyclase activator 1B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GUCA1B mRNA CTD PMID:36139627 NCBI chr 9:21,097,274...21,105,107
Ensembl chr 9:21,097,274...21,105,107
JBrowse link
G H1f2 H1.2 linker histone, cluster member multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of H1-2 mRNA CTD PMID:36139627 NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317
JBrowse link
G H2ac22 H2A clustered histone 22 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of H2AC11 mRNA CTD PMID:36139627 NCBI chr17:41,812,378...41,812,875
Ensembl chr17:41,797,862...41,812,946
JBrowse link
G H2ac6 H2A clustered histone 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of H2AC6 mRNA CTD PMID:36139627 NCBI chr17:47,403,701...47,404,167 JBrowse link
G Hal histidine ammonia lyase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HAL mRNA CTD PMID:36139627 NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HAPLN2 mRNA CTD PMID:36139627 NCBI chr 2:175,786,767...175,794,515
Ensembl chr 2:175,789,009...175,794,438
JBrowse link
G Has3 hyaluronan synthase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HAS3 mRNA CTD PMID:36139627 NCBI chr19:51,668,276...51,691,042 JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HBEGF mRNA CTD PMID:36139627 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220
JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HECW2 mRNA CTD PMID:36139627 NCBI chr 9:62,853,904...63,247,472
Ensembl chr 9:62,859,645...63,074,758
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HERC6 mRNA CTD PMID:36139627 NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HEY1 mRNA CTD PMID:36139627 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HEYL mRNA CTD PMID:36139627 NCBI chr 5:140,793,271...140,810,262
Ensembl chr 5:140,793,271...140,810,262
JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HIC1 mRNA CTD PMID:36139627 NCBI chr10:60,512,855...60,517,812
Ensembl chr10:60,500,565...60,523,448
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HILPDA mRNA CTD PMID:36139627 NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:58,836,463...58,839,423
JBrowse link
G Hivep2 HIVEP zinc finger 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HIVEP2 mRNA CTD PMID:36139627 NCBI chr 1:10,176,880...10,376,089
Ensembl chr 1:10,179,402...10,376,089
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HK2 mRNA CTD PMID:36139627 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
JBrowse link
G Hkdc1 hexokinase domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HKDC1 mRNA CTD PMID:36139627 NCBI chr20:30,878,037...30,917,044
Ensembl chr20:30,878,319...30,916,704
JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HOGA1 mRNA CTD PMID:36139627 NCBI chr 1:250,806,430...250,833,544
Ensembl chr 1:250,806,255...250,833,869
JBrowse link
G Hoxa13 homeo box A13 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HOXA13 mRNA CTD PMID:36139627 NCBI chr 4:82,689,566...82,691,701
Ensembl chr 4:82,689,566...82,691,701
JBrowse link
G Hoxb9 homeo box B9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HOXB9 mRNA CTD PMID:36139627 NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,733,658...81,738,872
JBrowse link
G Hoxc4 homeo box C4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HOXC4 mRNA CTD PMID:36139627 NCBI chr 7:136,049,059...136,051,601
Ensembl chr 7:136,049,059...136,051,601
JBrowse link
G Hpcal4 hippocalcin-like 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HPCAL4 mRNA CTD PMID:36139627 NCBI chr 5:140,739,577...140,751,529
Ensembl chr 5:140,739,635...140,751,530
JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HS3ST3B1 mRNA CTD PMID:36139627 NCBI chr10:49,060,693...49,093,185
Ensembl chr10:49,060,693...49,093,185
JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HSD17B14 mRNA CTD PMID:36139627 NCBI chr 1:105,165,695...105,176,045
Ensembl chr 1:105,165,695...105,176,510
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HSPA1A mRNA CTD PMID:36139627 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
JBrowse link
G Htra1 HtrA serine peptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HTRA1 mRNA CTD PMID:36139627 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
JBrowse link
G Hunk hormonally upregulated Neu-associated kinase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HUNK mRNA CTD PMID:36139627 NCBI chr11:43,127,244...43,244,502
Ensembl chr11:43,127,244...43,244,502
JBrowse link
G Hyal1 hyaluronidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HYAL1 mRNA CTD PMID:36139627 NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:117,129,277...117,133,146
JBrowse link
G Ifi35 interferon-induced protein 35 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of IFI35 mRNA CTD PMID:36139627 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750
JBrowse link
G Ifnlr1 interferon, lambda receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IFNLR1 mRNA CTD PMID:36139627 NCBI chr 5:153,203,597...153,225,911
Ensembl chr 5:153,203,597...153,225,911
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IGF2BP3 mRNA CTD PMID:36139627 NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IGFBP1 mRNA CTD PMID:36139627 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IL1B mRNA CTD PMID:36139627 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IL1RAPL1 mRNA CTD PMID:36139627 NCBI chr  X:55,322,779...56,827,486
Ensembl chr  X:55,328,964...56,826,613
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IL6R mRNA CTD PMID:36139627 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Inka1 inka box actin regulator 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of INKA1 mRNA CTD PMID:36139627 NCBI chr 8:117,552,875...117,554,565
Ensembl chr 8:117,552,875...117,554,565
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of INPP5D mRNA CTD PMID:36139627 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589
JBrowse link
G Insyn1 inhibitory synaptic factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of INSYN1 mRNA CTD PMID:36139627 NCBI chr 8:67,799,989...67,810,685
Ensembl chr 8:67,799,304...67,814,536
JBrowse link
G Iqank1 IQ motif and ankyrin repeat containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IQANK1 mRNA CTD PMID:36139627 NCBI chr 7:109,605,642...109,639,854
Ensembl chr 7:109,605,703...109,639,853
JBrowse link
G Iqcn IQ motif containing N multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of IQCN mRNA CTD PMID:36139627 NCBI chr16:18,750,492...18,766,184
Ensembl chr16:18,750,353...18,767,534
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IRAK2 mRNA CTD PMID:36139627 NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of IRF1 mRNA CTD PMID:36139627 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
JBrowse link
G Ism2 isthmin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ISM2 mRNA CTD PMID:36139627 NCBI chr 6:112,652,772...112,675,098
Ensembl chr 6:112,657,122...112,675,295
JBrowse link
G Itga10 integrin subunit alpha 10 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGA10 mRNA CTD PMID:36139627 NCBI chr 2:186,871,711...186,891,012
Ensembl chr 2:186,871,711...186,891,012
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGA2 mRNA CTD PMID:36139627 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509
JBrowse link
G Itgax integrin subunit alpha X multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGAX mRNA CTD PMID:36139627 NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:192,149,905...192,171,151
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGB3 mRNA CTD PMID:36139627 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
JBrowse link
G Itgb4 integrin subunit beta 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGB4 mRNA CTD PMID:36139627 NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932
JBrowse link
G Jak3 Janus kinase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of JAK3 mRNA CTD PMID:36139627 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
JBrowse link
G Jam2 junctional adhesion molecule 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of JAM2 mRNA CTD PMID:36139627 NCBI chr11:37,316,287...37,366,517
Ensembl chr11:37,317,511...37,367,510
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KCNJ4 mRNA CTD PMID:36139627 NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:112,922,532...112,954,826
JBrowse link
G Kcnk5 potassium two pore domain channel subfamily K member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KCNK5 mRNA CTD PMID:36139627 NCBI chr15:4,171,625...4,213,896
Ensembl chr15:4,171,610...4,213,897
JBrowse link
G Kdm7a lysine demethylase 7A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KDM7A mRNA CTD PMID:36139627 NCBI chr 4:68,866,263...68,992,979
Ensembl chr 4:68,871,677...68,931,506
JBrowse link
G Kiaa1755 KIAA1755 ortholog multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KIAA1755 mRNA CTD PMID:36139627 NCBI chr 3:167,270,476...167,305,337
Ensembl chr 3:167,192,612...167,304,240
JBrowse link
G Kif17 kinesin family member 17 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KIF17 mRNA CTD PMID:36139627 NCBI chr 5:155,765,592...155,802,941
Ensembl chr 5:155,765,592...155,803,247
JBrowse link
G Klf7 KLF transcription factor 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KLF7 mRNA CTD PMID:36139627 NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:72,933,136...73,020,056
JBrowse link
G Klhdc7a kelch domain containing 7A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KLHDC7A mRNA CTD PMID:36139627 NCBI chr 5:157,501,740...157,507,843
Ensembl chr 5:157,485,191...157,507,954
JBrowse link
G Klhdc7b kelch domain containing 7B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KLHDC7B mRNA CTD PMID:36139627 NCBI chr 7:122,331,708...122,335,364
Ensembl chr 7:122,331,708...122,335,364
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases response to substance
affects binding
multiple interactions
ISO KRAS protein mutant form results in increased susceptibility to sotorasib
sotorasib binds to KRAS protein mutant form
KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK1 protein]; KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK3 protein]
CTD PMID:31666701 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
JBrowse link
G Krt15 keratin 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KRT15 mRNA CTD PMID:36139627 NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142
JBrowse link
G Krt7 keratin 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KRT7 mRNA CTD PMID:36139627 NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786
JBrowse link
G Krt86 keratin 86 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KRT86 mRNA CTD PMID:36139627 NCBI chr 7:134,470,224...134,476,873
Ensembl chr 7:134,470,224...134,476,873
JBrowse link
G Lad1 ladinin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAD1 mRNA CTD PMID:36139627 NCBI chr13:49,801,347...49,815,709
Ensembl chr13:49,800,472...49,815,709
JBrowse link
G Lama2 laminin subunit alpha 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAMA2 mRNA CTD PMID:36139627 NCBI chr 1:19,492,126...20,140,056
Ensembl chr 1:19,244,599...20,140,056
JBrowse link
G Lama4 laminin subunit alpha 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAMA4 mRNA CTD PMID:36139627 NCBI chr20:43,946,898...44,087,972
Ensembl chr20:43,946,898...44,087,972
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAMC2 mRNA CTD PMID:36139627 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LAPTM5 mRNA CTD PMID:36139627 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927
JBrowse link
G Lat2 linker for activation of T cells family, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LAT2 mRNA CTD PMID:36139627 NCBI chr12:27,740,647...27,754,760
Ensembl chr12:27,740,654...27,755,843
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LCP1 mRNA CTD PMID:36139627 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLR mRNA CTD PMID:36139627 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
JBrowse link
G Ldlrad1 low density lipoprotein receptor class A domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLRAD1 mRNA CTD PMID:36139627 NCBI chr 5:127,212,581...127,229,753
Ensembl chr 5:127,220,764...127,229,725
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LDLRAD4 mRNA CTD PMID:36139627 NCBI chr18:63,789,089...64,118,166
Ensembl chr18:63,790,440...64,113,064
JBrowse link
G Lemd1 LEM domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LEMD1 mRNA CTD PMID:36139627 NCBI chr13:46,183,860...46,250,105
Ensembl chr13:46,218,085...46,250,562
JBrowse link
G Lgals9 galectin 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LGALS9 mRNA CTD PMID:36139627 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070
JBrowse link
G Lgi3 leucine-rich repeat LGI family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LGI3 mRNA CTD PMID:36139627 NCBI chr15:52,015,317...52,022,445
Ensembl chr15:52,015,230...52,022,443
JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LHX1 mRNA CTD PMID:36139627 NCBI chr10:69,894,288...69,901,076
Ensembl chr10:69,894,288...69,901,076
JBrowse link
G Lhx6 LIM homeobox 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LHX6 mRNA CTD PMID:36139627 NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559
JBrowse link
G Lipg lipase G, endothelial type multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LIPG mRNA CTD PMID:36139627 NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260
JBrowse link
G Liph lipase H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LIPH mRNA CTD PMID:36139627 NCBI chr11:92,536,724...92,586,117
Ensembl chr11:92,537,860...92,586,120
JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LONRF3 mRNA CTD PMID:36139627 NCBI chr  X:120,430,975...120,469,648
Ensembl chr  X:120,430,996...120,464,572
JBrowse link
G Lox lysyl oxidase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LOX mRNA CTD PMID:36139627 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
JBrowse link
G Lratd2 LRAT domain containing 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LRATD2 mRNA CTD PMID:36139627 NCBI chr 7:94,270,753...94,276,445
Ensembl chr 7:94,073,513...94,277,046
JBrowse link
G Lrrc37a leucine rich repeat containing 37A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LRRC37A3 mRNA CTD PMID:36139627 NCBI chr10:88,896,517...88,933,472
Ensembl chr10:88,896,703...88,933,361
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LSR mRNA CTD PMID:36139627 NCBI chr 1:95,313,830...95,329,471
Ensembl chr 1:95,313,033...95,329,354
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LTBP1 mRNA CTD PMID:36139627 NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LTBP2 mRNA CTD PMID:36139627 NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298
JBrowse link
G Lyst lysosomal trafficking regulator multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LYST mRNA CTD PMID:36139627 NCBI chr17:93,225,509...93,427,650
Ensembl chr17:93,225,540...93,427,650
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LZTS1 mRNA CTD PMID:36139627 NCBI chr16:25,309,502...25,364,942
Ensembl chr16:25,309,507...25,364,940
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MAD1L1 mRNA CTD PMID:36139627 NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MAFF mRNA CTD PMID:36139627 NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147
JBrowse link
G Map1a microtubule-associated protein 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MAP1A mRNA CTD PMID:36139627 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159
JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MAP4K1 mRNA CTD PMID:36139627 NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:93,398,454...93,419,993
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK1 protein] CTD PMID:31666701 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO sotorasib results in decreased phosphorylation of MAPK3 protein
KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK3 protein]
CTD PMID:31666701 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Marchf4 membrane associated ring-CH-type finger 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MARCHF4 mRNA CTD PMID:36139627 NCBI chr 9:81,527,703...81,647,448
Ensembl chr 9:81,527,703...81,647,448
JBrowse link
G Mast4 microtubule associated serine/threonine kinase family member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MAST4 mRNA CTD PMID:36139627 NCBI chr 2:35,627,190...36,219,090
Ensembl chr 2:35,627,190...36,218,832
JBrowse link
G Matn2 matrilin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MATN2 mRNA CTD PMID:36139627 NCBI chr 7:67,380,140...67,529,767
Ensembl chr 7:67,380,168...67,530,153
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MCTP1 mRNA CTD PMID:36139627 NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:7,803,382...8,493,596
JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MDGA1 mRNA CTD PMID:36139627 NCBI chr20:7,901,856...7,965,834
Ensembl chr20:7,901,856...7,965,834
JBrowse link
G Meis1 Meis homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MEIS1 mRNA CTD PMID:36139627 NCBI chr14:97,356,949...97,499,646
Ensembl chr14:97,322,748...97,495,083
JBrowse link
G Mest mesoderm specific transcript multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MEST mRNA CTD PMID:36139627 NCBI chr 4:60,321,814...60,332,288
Ensembl chr 4:60,316,102...60,333,509
JBrowse link
G Mid1 midline 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MID1 mRNA CTD PMID:36139627 NCBI chr  X:27,678,248...28,053,049
Ensembl chr  X:27,681,867...27,906,105
JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MILR1 mRNA CTD PMID:36139627 NCBI chr10:92,184,002...92,205,001
Ensembl chr10:92,187,479...92,205,003
JBrowse link
G Mlph melanophilin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MLPH mRNA CTD PMID:36139627 NCBI chr 9:98,955,036...98,990,566
Ensembl chr 9:98,955,141...98,990,556
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP1 mRNA CTD PMID:36139627 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP12 mRNA CTD PMID:36139627 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP13 mRNA CTD PMID:36139627 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP14 mRNA CTD PMID:36139627 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
JBrowse link
G Mmp19 matrix metallopeptidase 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MMP19 mRNA CTD PMID:36139627 NCBI chr 7:1,805,732...1,814,054
Ensembl chr 7:1,805,860...1,814,863
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP3 mRNA CTD PMID:36139627 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP9 mRNA CTD PMID:36139627 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Morn3 MORN repeat containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MORN3 mRNA CTD PMID:36139627 NCBI chr12:39,166,463...39,190,737
Ensembl chr12:39,168,112...39,189,367
JBrowse link
G Mpzl2 myelin protein zero-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MPZL2 mRNA CTD PMID:36139627 NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:54,243,556...54,256,074
JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MRAP2 mRNA CTD PMID:36139627 NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:96,988,079...97,024,579
JBrowse link
G Muc3a mucin 3A, cell surface associated multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MUC3A mRNA CTD PMID:36139627 NCBI chr12:25,082,728...25,091,494
Ensembl chr12:25,082,837...25,097,265
JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MUC5B mRNA CTD PMID:36139627 NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:206,346,400...206,378,367
JBrowse link
G Mybph myosin binding protein H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYBPH mRNA CTD PMID:36139627 NCBI chr13:48,205,162...48,212,928
Ensembl chr13:48,205,269...48,212,928
JBrowse link
G Myh15 myosin, heavy chain 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYH15 mRNA CTD PMID:36139627 NCBI chr11:65,084,666...65,226,010
Ensembl chr11:65,084,467...65,245,716
JBrowse link
G Myo10 myosin X multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO10 mRNA CTD PMID:36139627 NCBI chr 2:77,831,532...78,036,137
Ensembl chr 2:77,831,532...78,036,137
JBrowse link
G Myo15a myosin XVA multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO15A mRNA CTD PMID:36139627 NCBI chr10:45,776,907...45,835,473
Ensembl chr10:45,776,907...45,835,473
JBrowse link
G Myo15b myosin XVB multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO15B mRNA CTD PMID:36139627 NCBI chr10:101,587,672...101,625,092
Ensembl chr10:101,587,672...101,625,092
JBrowse link
G Myo5c myosin VC multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MYO5C mRNA CTD PMID:36139627 NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996
JBrowse link
G Myo7b myosin VIIb multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO7B mRNA CTD PMID:36139627 NCBI chr18:23,862,533...23,944,081
Ensembl chr18:23,862,533...23,944,049
JBrowse link
G N4bp3 Nedd4 binding protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of N4BP3 mRNA CTD PMID:36139627 NCBI chr10:36,400,053...36,407,609
Ensembl chr10:36,400,057...36,407,637
JBrowse link
G Nav3 neuron navigator 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NAV3 mRNA CTD PMID:36139627 NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NDRG1 mRNA CTD PMID:36139627 NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913
JBrowse link
G Ndrg4 NDRG family member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NDRG4 mRNA CTD PMID:36139627 NCBI chr19:9,357,470...9,393,465
Ensembl chr19:9,357,470...9,392,972
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NDUFV2 mRNA CTD PMID:36139627 NCBI chr 9:113,137,305...113,157,571
Ensembl chr 9:113,137,306...113,157,520
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NEDD9 mRNA CTD PMID:36139627 NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,495,492...23,675,668
JBrowse link
G Nes nestin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NES mRNA CTD PMID:36139627 NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NEURL3 mRNA CTD PMID:36139627 NCBI chr 9:45,990,373...45,998,470
Ensembl chr 9:45,990,375...45,998,535
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NGEF mRNA CTD PMID:36139627 NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:95,594,823...95,692,251
JBrowse link
G Nhsl1 NHS-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NHSL1 mRNA CTD PMID:36139627 NCBI chr 1:14,775,874...15,008,327
Ensembl chr 1:14,705,839...15,008,327
JBrowse link
G Nhsl2 NHS-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NHSL2 mRNA CTD PMID:36139627 NCBI chr  X:71,009,940...71,249,427
Ensembl chr  X:71,009,949...71,241,289
JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NIM1K mRNA CTD PMID:36139627 NCBI chr 2:53,403,467...53,451,248
Ensembl chr 2:53,403,473...53,419,656
JBrowse link
G Nipal4 NIPA-like domain containing 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NIPAL4 mRNA CTD PMID:36139627 NCBI chr10:31,085,267...31,101,979
Ensembl chr10:31,085,267...31,101,979
JBrowse link
G Nkx2-1 NK2 homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NKX2-1 mRNA CTD PMID:36139627 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:79,731,677...79,736,441
JBrowse link
G Nlgn1 neuroligin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NLGN1 mRNA CTD PMID:36139627 NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:110,186,573...110,909,984
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NLRP1 mRNA CTD PMID:36139627 NCBI chr10:56,277,134...56,332,229
Ensembl chr10:56,277,134...56,323,880
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NMNAT2 mRNA CTD PMID:36139627 NCBI chr13:67,655,794...67,831,609
Ensembl chr13:67,655,807...67,831,608
JBrowse link
G Nog noggin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NOG mRNA CTD PMID:36139627 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103
JBrowse link
G Notch4 notch receptor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NOTCH4 mRNA CTD PMID:36139627 NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072
JBrowse link
G Npas1 neuronal PAS domain protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NPAS1 mRNA CTD PMID:36139627 NCBI chr 1:86,295,509...86,316,018
Ensembl chr 1:86,295,515...86,314,893
JBrowse link
G Npb neuropeptide B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NPB mRNA CTD PMID:36139627 NCBI chr10:106,382,307...106,385,566
Ensembl chr10:106,384,779...106,385,878
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NPR3 mRNA CTD PMID:36139627 NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066
JBrowse link
G Nptx1 neuronal pentraxin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NPTX1 mRNA CTD PMID:36139627 NCBI chr10:105,309,578...105,318,829
Ensembl chr10:105,309,578...105,318,863
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NR1D1 mRNA CTD PMID:36139627 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NR3C2 mRNA CTD PMID:36139627 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
JBrowse link
G Nrep neuronal regeneration related protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NREP mRNA CTD PMID:36139627 NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742
JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NRP1 mRNA CTD PMID:36139627 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702
JBrowse link
G Nrp2 neuropilin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NRP2 mRNA CTD PMID:36139627 NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NT5E mRNA CTD PMID:36139627 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
JBrowse link
G Ntsr1 neurotensin receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NTSR1 mRNA CTD PMID:36139627 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:187,983,778...188,033,934
JBrowse link
G Nyap1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NYAP1 mRNA CTD PMID:36139627 NCBI chr12:24,591,574...24,604,417
Ensembl chr12:24,593,064...24,604,336
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of OAS1 mRNA CTD PMID:36139627 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of OAS3 mRNA CTD PMID:36139627 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:41,439,643...41,464,420
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of OASL mRNA CTD PMID:36139627 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483
JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of OBSCN mRNA CTD PMID:36139627 NCBI chr10:44,273,686...44,419,275
Ensembl chr10:44,288,866...44,419,297
JBrowse link
G Onecut3 one cut homeobox 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ONECUT3 mRNA CTD PMID:36139627 NCBI chr 7:9,850,685...9,869,988
Ensembl chr 7:9,850,685...9,869,988
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of OSGIN1 mRNA CTD PMID:36139627 NCBI chr19:64,380,336...64,409,165
Ensembl chr19:64,401,173...64,409,162
JBrowse link
G P2rx6 purinergic receptor P2X 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of P2RX6 mRNA CTD PMID:36139627 NCBI chr11:96,944,167...96,956,424
Ensembl chr11:96,944,169...96,954,646
JBrowse link
G P3h2 prolyl 3-hydroxylase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of P3H2 mRNA CTD PMID:36139627 NCBI chr11:88,139,086...88,280,221
Ensembl chr11:88,139,078...88,281,203
JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PAG1 mRNA CTD PMID:36139627 NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:93,964,594...93,977,227
JBrowse link
G Paqr5 progestin and adipoQ receptor family member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PAQR5 mRNA CTD PMID:36139627 NCBI chr 8:71,327,397...71,409,201
Ensembl chr 8:71,327,397...71,409,201
JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PAQR9 mRNA CTD PMID:36139627 NCBI chr 8:104,993,884...104,996,180
Ensembl chr 8:104,993,827...104,998,285
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PBLD mRNA CTD PMID:36139627 NCBI chr20:25,549,974...25,565,390
Ensembl chr20:25,549,974...25,565,226
JBrowse link
G Pcdhb19 protocadherin beta 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PCDHB12 mRNA CTD PMID:36139627 NCBI chr18:29,478,848...29,481,656 JBrowse link
G Pde2a phosphodiesterase 2A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PDE2A mRNA CTD PMID:36139627 NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466
JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PDP2 mRNA CTD PMID:36139627 NCBI chr19:392,858...400,529
Ensembl chr19:392,183...400,902
JBrowse link
G Per1 period circadian regulator 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PER1 mRNA CTD PMID:36139627 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PFKFB4 mRNA CTD PMID:36139627 NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:118,522,365...118,565,468
JBrowse link
G Pfn4 profilin family, member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PFN4 mRNA CTD PMID:36139627 NCBI chr 6:33,506,077...33,516,163
Ensembl chr 6:33,506,077...33,516,163
JBrowse link
G Pgbd5 piggyBac transposable element derived 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PGBD5 mRNA CTD PMID:36139627 NCBI chr19:69,234,171...69,299,315
Ensembl chr19:69,234,171...69,299,560
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PHLDA2 mRNA CTD PMID:36139627 NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PHOSPHO1 mRNA CTD PMID:36139627 NCBI chr10:81,258,810...81,266,345
Ensembl chr10:81,257,427...81,268,481
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PHTF1 mRNA CTD PMID:36139627 NCBI chr 2:194,161,343...194,249,925
Ensembl chr 2:194,161,000...194,219,530
JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PHYHIP mRNA CTD PMID:36139627 NCBI chr15:51,943,670...51,954,921
Ensembl chr15:51,943,378...51,954,920
JBrowse link
G Piezo2 piezo-type mechanosensitive ion channel component 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PIEZO2 mRNA CTD PMID:36139627 NCBI chr18:58,738,734...59,115,252
Ensembl chr18:58,738,740...59,115,215
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PIK3IP1 mRNA CTD PMID:36139627 NCBI chr14:82,428,315...82,440,261
Ensembl chr14:82,428,248...82,440,260
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PIK3R3 mRNA CTD PMID:36139627 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PIWIL2 mRNA CTD PMID:36139627 NCBI chr15:51,841,104...51,907,729
Ensembl chr15:51,841,405...51,907,819
JBrowse link
G Pkd1l2 polycystin 1 like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PKD1L2 mRNA CTD PMID:36139627 NCBI chr19:61,958,351...62,045,324
Ensembl chr19:61,958,415...62,044,358
JBrowse link
G Plac1 placenta enriched 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLAC1 mRNA CTD PMID:36139627 NCBI chr  X:137,740,896...137,874,688
Ensembl chr  X:137,740,890...137,905,210
JBrowse link
G Plag1 PLAG1 zinc finger multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLAG1 mRNA CTD PMID:36139627 NCBI chr 5:21,699,650...21,754,325
Ensembl chr 5:21,702,987...21,711,240
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PLAT mRNA CTD PMID:36139627 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLAUR mRNA CTD PMID:36139627 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130
JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLCXD3 mRNA CTD PMID:36139627 NCBI chr 2:55,294,597...55,473,968
Ensembl chr 2:55,294,613...55,474,220
JBrowse link
G Pld1 phospholipase D1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PLD1 mRNA CTD PMID:36139627 NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245
JBrowse link
G Plek2 pleckstrin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLEK2 mRNA CTD PMID:36139627 NCBI chr 6:103,434,156...103,452,457
Ensembl chr 6:103,434,156...103,452,371
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLIN1 mRNA CTD PMID:36139627 NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206
JBrowse link
G Plin4 perilipin 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLIN4 mRNA CTD PMID:36139627 NCBI chr 9:1,016,334...1,025,249
Ensembl chr 9:1,016,302...1,025,368
JBrowse link
G Plxna2 plexin A2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PLXNA2 mRNA CTD PMID:36139627 NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453
JBrowse link
G Podxl podocalyxin-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PODXL mRNA CTD PMID:36139627 NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789
JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POU2F2 mRNA CTD PMID:36139627 NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564
JBrowse link
G Pou2f3 POU class 2 homeobox 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POU2F3 mRNA CTD PMID:36139627 NCBI chr 8:52,392,363...52,474,756
Ensembl chr 8:52,392,497...52,474,756
JBrowse link
G Pou6f1 POU class 6 homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POU6F1 mRNA CTD PMID:36139627 NCBI chr 7:133,556,506...133,580,004
Ensembl chr 7:133,558,928...133,579,671
JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PPFIA3 mRNA CTD PMID:36139627 NCBI chr 1:104,953,598...104,982,373
Ensembl chr 1:104,953,598...104,982,278
JBrowse link
G Ppm1n protein phosphatase, Mg2+/Mn2+ dependent 1N multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PPM1N mRNA CTD PMID:36139627 NCBI chr 1:88,057,365...88,062,912
Ensembl chr 1:88,058,624...88,060,700
JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PPP1R16B mRNA CTD PMID:36139627 NCBI chr 3:167,743,518...167,839,511
Ensembl chr 3:167,743,952...167,839,242
JBrowse link
G Prag1 PEAK1 related kinase activating pseudokinase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRAG1 mRNA CTD PMID:36139627 NCBI chr16:62,791,249...62,844,532
Ensembl chr16:62,786,329...62,844,532
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PREX1 mRNA CTD PMID:36139627 NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRICKLE1 mRNA CTD PMID:36139627 NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:126,518,587...126,614,581
JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRKG2 mRNA CTD PMID:36139627 NCBI chr14:10,864,020...10,972,617
Ensembl chr14:10,864,186...10,972,614
JBrowse link
G Prnd prion like protein doppel multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRND mRNA CTD PMID:36139627 NCBI chr 3:139,666,383...139,671,647
Ensembl chr 3:139,666,068...139,671,890
JBrowse link
G Prodh1 proline dehydrogenase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PRODH mRNA CTD PMID:36139627 NCBI chr11:96,414,275...96,431,604
Ensembl chr11:96,414,224...96,433,418
JBrowse link
G Prodh2 proline dehydrogenase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRODH2 mRNA CTD PMID:36139627 NCBI chr 1:94,881,000...94,894,609
Ensembl chr 1:94,881,061...94,894,609
JBrowse link
G Prr5l proline rich 5 like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRR5L mRNA CTD PMID:36139627 NCBI chr 3:108,458,107...108,628,552
Ensembl chr 3:108,458,633...108,537,763
JBrowse link
G Prss22 serine protease 22 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRSS22 mRNA CTD PMID:36139627 NCBI chr10:13,533,725...13,538,435
Ensembl chr10:13,533,725...13,538,435
JBrowse link
G Prss53 serine protease 53 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRSS53 mRNA CTD PMID:36139627 NCBI chr 1:191,923,398...191,931,292
Ensembl chr 1:191,925,434...191,955,449
JBrowse link
G Prtn3 proteinase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRTN3 mRNA CTD PMID:36139627 NCBI chr 7:10,472,750...10,482,037
Ensembl chr 7:10,472,755...10,482,474
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PSD3 mRNA CTD PMID:36139627 NCBI chr16:26,238,595...26,802,535
Ensembl chr16:26,340,028...26,802,535
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PSMB10 mRNA CTD PMID:36139627 NCBI chr19:50,740,808...50,743,292
Ensembl chr19:50,740,811...50,743,210
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PSMB9 mRNA CTD PMID:36139627 NCBI chr20:4,668,952...4,674,421
Ensembl chr20:4,668,739...4,674,421
JBrowse link
G Ptgir prostaglandin I2 receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PTGIR mRNA CTD PMID:36139627 NCBI chr 1:86,707,690...86,710,073
Ensembl chr 1:86,707,503...86,711,874
JBrowse link
G Ptk6 protein tyrosine kinase 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PTK6 mRNA CTD PMID:36139627 NCBI chr 3:188,684,633...188,693,224
Ensembl chr 3:188,684,633...188,693,224
JBrowse link
G Pxmp2 peroxisomal membrane protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PXMP2 mRNA CTD PMID:36139627 NCBI chr12:52,053,951...52,064,283
Ensembl chr12:52,053,788...52,064,283
JBrowse link
G Pygb glycogen phosphorylase B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PYGB mRNA CTD PMID:36139627 NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961
JBrowse link
G Rab11fip4 RAB11 family interacting protein 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB11FIP4 mRNA CTD PMID:36139627 NCBI chr10:65,048,070...65,156,086
Ensembl chr10:65,048,140...65,152,722
JBrowse link
G Rab38 RAB38, member RAS oncogene family multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB38 mRNA CTD PMID:36139627 NCBI chr 1:151,595,153...151,675,492
Ensembl chr 1:151,595,078...151,675,493
JBrowse link
G Rab39a RAB39A, member RAS oncogene family multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB39A mRNA CTD PMID:36139627 NCBI chr 8:62,984,434...63,002,053
Ensembl chr 8:62,984,434...63,002,053
JBrowse link
G Rab7b Rab7b, member RAS oncogene family multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB7B mRNA CTD PMID:36139627 NCBI chr13:45,673,396...45,699,798
Ensembl chr13:45,673,416...45,709,933
JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAC2 mRNA CTD PMID:36139627 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267
JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAPGEF5 mRNA CTD PMID:36139627 NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:144,580,976...144,822,908
JBrowse link
G Rasa4 RAS p21 protein activator 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RASA4B mRNA CTD PMID:36139627 NCBI chr12:26,189,416...26,216,801
Ensembl chr12:26,189,339...26,216,860
JBrowse link
G Rasl11a RAS-like family 11 member A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RASL11A mRNA CTD PMID:36139627 NCBI chr12:13,372,023...13,374,784
Ensembl chr12:13,372,023...13,376,451
JBrowse link
G Rassf9 Ras association domain family member 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RASSF9 mRNA CTD PMID:36139627 NCBI chr 7:39,486,257...39,518,090
Ensembl chr 7:39,409,870...39,519,675
JBrowse link
G Reep1 receptor accessory protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of REEP1 mRNA CTD PMID:36139627 NCBI chr 4:105,303,974...105,420,611
Ensembl chr 4:105,303,969...105,420,602
JBrowse link
G Rem2 RRAD and GEM like GTPase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of REM2 mRNA CTD PMID:36139627 NCBI chr15:31,903,972...31,908,451
Ensembl chr15:31,903,965...31,908,445
JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RGMB mRNA CTD PMID:36139627 NCBI chr 1:65,439,748...65,465,149
Ensembl chr 1:65,441,410...65,465,098
JBrowse link
G Ribc2 RIB43A domain with coiled-coils 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RIBC2 mRNA CTD PMID:36139627 NCBI chr 7:118,122,722...118,137,772
Ensembl chr 7:118,122,408...118,137,767
JBrowse link
G Rimkla ribosomal modification protein rimK-like family member A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RIMKLA mRNA CTD PMID:36139627 NCBI chr 5:138,357,463...138,384,132
Ensembl chr 5:138,359,743...138,384,060
JBrowse link
G Rnf182 ring finger protein 182 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RNF182 mRNA CTD PMID:36139627 NCBI chr17:21,232,084...21,287,329
Ensembl chr17:21,232,084...21,299,723
JBrowse link
G Rnf223 ring finger protein 223 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RNF223 mRNA CTD PMID:36139627 NCBI chr 5:172,005,566...172,008,456
Ensembl chr 5:172,005,566...172,008,458
JBrowse link
G Robo4 roundabout guidance receptor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ROBO4 mRNA CTD PMID:36139627 NCBI chr 8:45,308,739...45,322,522
Ensembl chr 8:45,308,739...45,322,531
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ROR2 mRNA CTD PMID:36139627 NCBI chr17:12,124,749...12,300,044
Ensembl chr17:12,124,749...12,300,044
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RORA mRNA CTD PMID:36139627 NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO sotorasib results in decreased phosphorylation of RPS6 protein CTD PMID:31666701 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
JBrowse link
G Rragd Ras-related GTP binding D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RRAGD mRNA CTD PMID:36139627 NCBI chr 5:52,170,234...52,205,700
Ensembl chr 5:52,169,783...52,209,000
JBrowse link
G Rspo1 R-spondin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RSPO1 mRNA CTD PMID:36139627 NCBI chr 5:142,536,162...142,557,611
Ensembl chr 5:142,536,344...142,557,776
JBrowse link
G RT1-Ha RT1 class II, locus Ha multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HLA-DPA1 mRNA CTD PMID:36139627 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141
JBrowse link
G Rtn2 reticulon 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RTN2 mRNA CTD PMID:36139627 NCBI chr 1:88,063,124...88,076,082
Ensembl chr 1:88,063,119...88,076,043
JBrowse link
G Rtp4 receptor (chemosensory) transporter protein 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RTP4 mRNA CTD PMID:36139627 NCBI chr11:90,741,992...90,840,061
Ensembl chr11:90,741,992...90,753,851
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RUNX2 mRNA CTD PMID:36139627 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
JBrowse link
G Rxfp4 relaxin family peptide/INSL5 receptor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RXFP4 mRNA CTD PMID:36139627 NCBI chr 2:176,421,332...176,422,486 JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RYR1 mRNA CTD PMID:36139627 NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305
JBrowse link
G S100a2 S100 calcium binding protein A2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of S100A2 mRNA CTD PMID:36139627 NCBI chr 2:178,374,659...178,375,903 JBrowse link
G Sall4 spalt-like transcription factor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SALL4 mRNA CTD PMID:36139627 NCBI chr 3:177,891,705...177,909,743
Ensembl chr 3:177,891,705...177,909,743
JBrowse link
G Samd15 sterile alpha motif domain containing 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SAMD15 mRNA CTD PMID:36139627 NCBI chr 6:112,572,352...112,587,142
Ensembl chr 6:112,572,501...112,576,796
JBrowse link
G Samd9l sterile alpha motif domain containing 9 like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SAMD9L mRNA CTD PMID:36139627 NCBI chr 4:32,316,748...32,331,112
Ensembl chr 4:32,222,623...32,331,067
JBrowse link
G Saxo5 stabilizer of axonemal microtubules 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SAXO5 mRNA CTD PMID:36139627 NCBI chr12:6,318,845...6,336,018
Ensembl chr12:6,318,903...6,336,009
JBrowse link
G Scarf1 scavenger receptor class F, member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SCARF1 mRNA CTD PMID:36139627 NCBI chr10:60,857,494...60,869,795
Ensembl chr10:60,857,478...60,869,810
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SCNN1B mRNA CTD PMID:36139627 NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:185,854,733...185,916,049
JBrowse link
G Sdcbp2 syndecan binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SDCBP2 mRNA CTD PMID:36139627 NCBI chr 3:160,521,309...160,558,452
Ensembl chr 3:160,530,927...160,558,446
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SEC14L2 mRNA CTD PMID:36139627 NCBI chr14:83,197,384...83,222,059
Ensembl chr14:83,197,387...83,217,317
JBrowse link
G Sema3c semaphorin 3C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SEMA3C mRNA CTD PMID:36139627 NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:18,538,454...18,701,740
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SEMA7A mRNA CTD PMID:36139627 NCBI chr 8:67,244,318...67,267,060
Ensembl chr 8:67,243,824...67,267,058
JBrowse link
G Serpina3n serpin family A member 3N multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINA3 mRNA CTD PMID:36139627 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415
JBrowse link
G Serpina5 serpin family A member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINA5 mRNA CTD PMID:36139627 NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:128,784,991...128,793,186
JBrowse link
G Serpinb8 serpin family B member 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINB8 mRNA CTD PMID:36139627 NCBI chr13:24,141,557...24,164,894
Ensembl chr13:24,129,855...24,166,076
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINE1 mRNA CTD PMID:36139627 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
JBrowse link
G Serpine2 serpin family E member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINE2 mRNA CTD PMID:36139627 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
JBrowse link
G Serpini1 serpin family I member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SERPINI1 mRNA CTD PMID:36139627 NCBI chr 2:162,645,209...162,731,737
Ensembl chr 2:162,645,350...162,731,740
JBrowse link
G Sfn stratifin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SFN mRNA CTD PMID:36139627 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995
JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SFXN2 mRNA CTD PMID:36139627 NCBI chr 1:255,388,428...255,400,724
Ensembl chr 1:255,388,429...255,409,780
JBrowse link
G Sfxn3 sideroflexin 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SFXN3 mRNA CTD PMID:36139627 NCBI chr 1:253,856,935...253,866,219
Ensembl chr 1:253,856,882...253,887,542
JBrowse link
G Sh2d5 SH2 domain containing 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SH2D5 mRNA CTD PMID:36139627 NCBI chr 5:155,753,087...155,763,936
Ensembl chr 5:155,750,803...155,763,936
JBrowse link
G Sh3d21 SH3 domain containing 21 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SH3D21 mRNA CTD PMID:36139627 NCBI chr 5:143,713,718...143,729,073
Ensembl chr 5:143,713,718...143,729,257
JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SH3TC2 mRNA CTD PMID:36139627 NCBI chr18:57,686,701...57,747,735
Ensembl chr18:57,686,735...57,800,541
JBrowse link
G Shf Src homology 2 domain containing F multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SHF mRNA CTD PMID:36139627 NCBI chr 3:129,749,903...129,769,912
Ensembl chr 3:129,749,584...129,769,929
JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SIGLEC15 mRNA CTD PMID:36139627 NCBI chr18:73,781,536...73,797,014
Ensembl chr18:73,781,536...73,797,014
JBrowse link
G Slc10a5 solute carrier family 10, member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC10A5 mRNA CTD PMID:36139627 NCBI chr 2:93,364,959...93,366,263
Ensembl chr 2:93,360,766...93,368,978
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC17A7 mRNA CTD PMID:36139627 NCBI chr 1:104,786,172...104,798,049
Ensembl chr 1:104,785,955...104,798,049
JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC2A3 mRNA CTD PMID:36139627 NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC47A2 mRNA CTD PMID:36139627 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425
JBrowse link
G Slc4a11 solute carrier family 4 member 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC4A11 mRNA CTD PMID:36139627 NCBI chr 3:138,353,305...138,365,983
Ensembl chr 3:138,353,305...138,365,754
JBrowse link
G Slc4a7 solute carrier family 4 member 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC4A7 mRNA CTD PMID:36139627 NCBI chr15:13,015,854...13,095,485
Ensembl chr15:13,015,854...13,095,292
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC5A1 mRNA CTD PMID:36139627 NCBI chr14:81,778,495...81,843,084
Ensembl chr14:81,778,348...81,846,624
JBrowse link
G Slc6a9 solute carrier family 6 member 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC6A9 mRNA CTD PMID:36139627 NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172
JBrowse link
G Slc9a3 solute carrier family 9 member A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC9A3 mRNA CTD PMID:36139627 NCBI chr 1:30,953,215...30,996,209
Ensembl chr 1:30,953,216...30,996,002
JBrowse link
G Slitrk3 SLIT and NTRK-like family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLITRK3 mRNA CTD PMID:36139627 NCBI chr 2:159,983,650...159,996,194
Ensembl chr 2:159,973,029...159,996,342
JBrowse link
G Smim5 small integral membrane protein 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SMIM5 mRNA CTD PMID:36139627 NCBI chr10:101,632,966...101,642,089
Ensembl chr10:101,632,966...101,638,746
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SMOC2 mRNA CTD PMID:36139627 NCBI chr 1:63,935,627...64,064,952
Ensembl chr 1:63,935,647...64,064,955
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SMPD3 mRNA CTD PMID:36139627 NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SNAI2 mRNA CTD PMID:36139627 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349
JBrowse link
G Snai3 snail family transcriptional repressor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SNAI3 mRNA CTD PMID:36139627 NCBI chr19:67,425,311...67,437,830
Ensembl chr19:67,425,157...67,434,268
JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SOCS2 mRNA CTD PMID:36139627 NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423
JBrowse link
G Spata18 spermatogenesis associated 18 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SPATA18 mRNA CTD PMID:36139627 NCBI chr14:34,885,995...34,912,704
Ensembl chr14:34,885,995...34,912,736
JBrowse link
G Spats2l spermatogenesis associated, serine-rich 2-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPATS2L mRNA CTD PMID:36139627 NCBI chr 9:66,814,217...66,988,084
Ensembl chr 9:66,814,228...66,988,578
JBrowse link
G Spns3 SPNS lysolipid transporter 3, sphingosine-1-phosphate multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPNS3 mRNA CTD PMID:36139627 NCBI chr10:57,612,796...57,667,601
Ensembl chr10:57,612,819...57,667,414
JBrowse link
G Spocd1 SPOC domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPOCD1 mRNA CTD PMID:36139627 NCBI chr 5:147,573,460...147,581,165 JBrowse link
G Spon1 spondin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPON1 mRNA CTD PMID:36139627 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:177,363,197...177,662,676
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SPSB1 mRNA CTD PMID:36139627 NCBI chr 5:165,641,255...165,701,482
Ensembl chr 5:165,642,851...165,654,225
JBrowse link
G Sptb spectrin, beta, erythrocytic multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPTB mRNA CTD PMID:36139627 NCBI chr 6:101,043,512...101,170,389
Ensembl chr 6:101,045,216...101,170,278
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPTBN4 mRNA CTD PMID:36139627 NCBI chr 1:91,778,379...91,865,970
Ensembl chr 1:91,778,380...91,865,049
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SRXN1 mRNA CTD PMID:36139627 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ST3GAL1 mRNA CTD PMID:36139627 NCBI chr 7:100,734,300...100,802,443
Ensembl chr 7:100,734,300...100,745,242
JBrowse link
G Stambpl1 STAM binding protein-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STAMBPL1 mRNA CTD PMID:36139627 NCBI chr 1:241,095,695...241,158,225
Ensembl chr 1:241,113,239...241,158,225
JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STC1 mRNA CTD PMID:36139627 NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082
JBrowse link
G Stn1 STN1 subunit of CST complex multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STN1 mRNA CTD PMID:36139627 NCBI chr 1:256,336,916...256,371,143
Ensembl chr 1:256,315,367...256,370,736
JBrowse link
G Stom stomatin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STOM mRNA CTD PMID:36139627 NCBI chr 3:39,042,503...39,064,818
Ensembl chr 3:39,042,503...39,064,818
JBrowse link
G Sulf2 sulfatase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SULF2 mRNA CTD PMID:36139627 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SULT2B1 mRNA CTD PMID:36139627 NCBI chr 1:105,336,614...105,397,744
Ensembl chr 1:105,336,614...105,397,744
JBrowse link
G Sycp2 synaptonemal complex protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYCP2 mRNA CTD PMID:36139627 NCBI chr 3:185,814,033...185,876,516
Ensembl chr 3:185,814,035...185,876,492
JBrowse link
G Sync syncoilin, intermediate filament protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SYNC mRNA CTD PMID:36139627 NCBI chr 5:146,915,715...146,940,547
Ensembl chr 5:146,916,361...146,943,191
JBrowse link
G Syne3 spectrin repeat containing, nuclear envelope family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYNE3 mRNA CTD PMID:36139627 NCBI chr 6:129,637,644...129,729,542
Ensembl chr 6:129,641,123...129,729,509
JBrowse link
G Syt12 synaptotagmin 12 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYT12 mRNA CTD PMID:36139627 NCBI chr 1:211,158,745...211,189,780
Ensembl chr 1:211,159,800...211,189,037
JBrowse link
G Syt5 synaptotagmin 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYT5 mRNA CTD PMID:36139627 NCBI chr 1:78,320,034...78,327,750
Ensembl chr 1:78,320,034...78,327,746
JBrowse link
G Sytl2 synaptotagmin-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYTL2 mRNA CTD PMID:36139627 NCBI chr 1:153,685,403...153,791,758
Ensembl chr 1:153,665,327...153,791,756
JBrowse link
G Tac3 tachykinin precursor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TAC3 mRNA CTD PMID:36139627 NCBI chr 7:65,447,817...65,454,427
Ensembl chr 7:65,447,817...65,454,427
JBrowse link
G Tafa2 TAFA chemokine like family member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TAFA2 mRNA CTD PMID:36139627 NCBI chr 7:60,827,985...61,303,873
Ensembl chr 7:60,891,958...61,303,869
JBrowse link
G Tapbpl TAP binding protein-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TAPBPL mRNA CTD PMID:36139627 NCBI chr 4:159,707,686...159,715,137
Ensembl chr 4:159,708,511...159,715,137
JBrowse link
G Tbx4 T-box transcription factor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TBX4 mRNA CTD PMID:36139627 NCBI chr10:71,228,145...71,258,222
Ensembl chr10:71,197,727...71,258,218
JBrowse link
G Tcaf2 TRPM8 channel-associated factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TCAF2 mRNA CTD PMID:36139627
G Tchh trichohyalin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TCHH mRNA CTD PMID:36139627 NCBI chr 2:181,787,109...181,795,463
Ensembl chr 2:181,787,109...181,795,463
JBrowse link
G Tex9 testis expressed 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TEX9 mRNA CTD PMID:36139627 NCBI chr 8:82,049,194...82,094,613
Ensembl chr 8:82,058,514...82,094,801
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TFPI2 mRNA CTD PMID:36139627 NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426
JBrowse link
G Tfr2 transferrin receptor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TFR2 mRNA CTD PMID:36139627 NCBI chr12:24,744,450...24,761,413
Ensembl chr12:24,744,450...24,761,413
JBrowse link
G Tjp3 tight junction protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TJP3 mRNA CTD PMID:36139627 NCBI chr 7:9,078,757...9,097,003
Ensembl chr 7:9,084,315...9,096,984
JBrowse link
G Tlcd1 TLC domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TLCD1 mRNA CTD PMID:36139627 NCBI chr10:63,572,541...63,574,574
Ensembl chr10:63,572,518...63,574,567
JBrowse link
G Tle6 TLE family member 6, subcortical maternal complex member multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TLE6 mRNA CTD PMID:36139627 NCBI chr 7:8,757,846...8,769,405
Ensembl chr 7:8,759,925...8,769,404
JBrowse link
G Tlr1 toll-like receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TLR1 mRNA CTD PMID:36139627 NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,740,379...43,756,243
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TLR3 mRNA CTD PMID:36139627 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:53,555,131...53,568,385
JBrowse link
G Tlr6 toll-like receptor 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TLR6 mRNA CTD PMID:36139627 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,698,751...43,740,462
JBrowse link
G Tm4sf19 transmembrane 4 L six family member 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TM4SF19 mRNA CTD PMID:36139627 NCBI chr11:81,876,714...81,899,603
Ensembl chr11:81,877,435...81,888,484
JBrowse link
G Tmc8 transmembrane channel-like 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMC8 mRNA CTD PMID:36139627 NCBI chr10:103,498,505...103,509,496
Ensembl chr10:103,499,041...103,509,294
JBrowse link
G Tmem117 transmembrane protein 117 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM117 mRNA CTD PMID:36139627 NCBI chr 7:127,636,862...128,098,944
Ensembl chr 7:127,636,825...128,098,941
JBrowse link
G Tmem144 transmembrane protein 144 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM144 mRNA CTD PMID:36139627 NCBI chr 2:167,258,788...167,291,701
Ensembl chr 2:167,258,789...167,290,902
JBrowse link
G Tmem156 transmembrane protein 156 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM156 mRNA CTD PMID:36139627 NCBI chr14:43,568,131...43,606,109
Ensembl chr14:43,577,023...43,606,109
JBrowse link
G Tmem158 transmembrane protein 158 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM158 mRNA CTD PMID:36139627 NCBI chr 8:131,791,137...131,792,135
Ensembl chr 8:131,787,277...131,796,882
JBrowse link
G Tmem236 transmembrane protein 236 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM236 mRNA CTD PMID:36139627 NCBI chr17:82,075,020...82,149,796
Ensembl chr17:82,096,528...82,148,211
JBrowse link
G Tmem25 transmembrane protein 25 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM25 mRNA CTD PMID:36139627 NCBI chr 8:54,003,907...54,009,469
Ensembl chr 8:54,003,907...54,009,325
JBrowse link
G Tmem255b transmembrane protein 255B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM255B mRNA CTD PMID:36139627 NCBI chr16:82,759,236...82,810,450
Ensembl chr16:82,774,136...82,808,929
JBrowse link
G Tmem269 transmembrane protein 269 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM269 mRNA CTD PMID:36139627 NCBI chr 5:138,102,637...138,121,078
Ensembl chr 5:138,102,637...138,115,353
JBrowse link
G Tmem270 transmembrane protein 270 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM270 mRNA CTD PMID:36139627 NCBI chr12:27,430,092...27,435,243
Ensembl chr12:27,429,985...27,435,242
JBrowse link
G Tmem45a transmembrane protein 45A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM45A mRNA CTD PMID:36139627 NCBI chr11:57,181,686...57,268,630
Ensembl chr11:57,182,785...57,282,722
JBrowse link
G Tmem92 transmembrane protein 92 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM92 mRNA CTD PMID:36139627 NCBI chr10:80,246,205...80,257,650 JBrowse link
G Tnfsf15 TNF superfamily member 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TNFSF15 mRNA CTD PMID:36139627 NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:82,150,376...82,171,882
JBrowse link
G Tnxb tenascin XB multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TNXB mRNA CTD PMID:36139627 Ensembl chr20:4,031,082...4,090,128 JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TP53I3 mRNA CTD PMID:36139627 NCBI chr 6:33,537,779...33,545,204 JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TPH1 mRNA CTD PMID:36139627 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484
JBrowse link
G Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TRANK1 mRNA CTD PMID:36139627 NCBI chr 8:120,153,381...120,233,879
Ensembl chr 8:120,154,362...120,234,087
JBrowse link
G Trib1 tribbles pseudokinase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIB1 mRNA CTD PMID:36139627 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:93,095,973...93,117,480
JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIB2 mRNA CTD PMID:36139627 NCBI chr 6:44,274,762...44,299,139
Ensembl chr 6:44,274,762...44,299,094
JBrowse link
G Trim29 tripartite motif-containing 29 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TRIM29 mRNA CTD PMID:36139627 NCBI chr 8:52,579,175...52,603,919
Ensembl chr 8:52,579,175...52,603,919
JBrowse link
G Trim63 tripartite motif containing 63 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIM63 mRNA CTD PMID:36139627 NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:151,817,225...151,831,058
JBrowse link
G Trim9 tripartite motif-containing 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIM9 mRNA CTD PMID:36139627 NCBI chr 6:94,492,789...94,592,597
Ensembl chr 6:94,493,268...94,592,551
JBrowse link
G Trmt9b tRNA methyltransferase 9B (putative) multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TRMT9B mRNA CTD PMID:36139627 NCBI chr16:62,439,625...62,495,526
Ensembl chr16:62,446,393...62,495,518
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRPV2 mRNA CTD PMID:36139627 NCBI chr10:47,772,223...47,797,956
Ensembl chr10:47,764,839...47,793,533
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TSC22D3 mRNA CTD PMID:36139627 NCBI chr  X:109,006,410...109,066,389
Ensembl chr  X:109,006,420...109,015,519
JBrowse link
G Tsnaxip1 translin-associated factor X interacting protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TSNAXIP1 mRNA CTD PMID:36139627 NCBI chr19:50,626,846...50,647,848
Ensembl chr19:50,626,920...50,644,688
JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TTC39A mRNA CTD PMID:36139627 NCBI chr 5:129,379,560...129,441,779
Ensembl chr 5:129,380,753...129,433,372
JBrowse link
G Ttpa alpha tocopherol transfer protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TTPA mRNA CTD PMID:36139627 NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:38,292,665...38,315,804
JBrowse link
G Tuba1a tubulin, alpha 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TUBA1A mRNA CTD PMID:36139627 NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035
JBrowse link
G Txk TXK tyrosine kinase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TXK mRNA CTD PMID:36139627 NCBI chr14:35,817,270...35,873,454
Ensembl chr14:35,817,893...35,873,460
JBrowse link
G Uap1l1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of UAP1L1 mRNA CTD PMID:36139627 NCBI chr 3:28,570,854...28,579,766
Ensembl chr 3:28,573,358...28,578,630
JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of UBA7 mRNA CTD PMID:36139627 NCBI chr 8:117,543,902...117,552,709
Ensembl chr 8:117,543,957...117,556,142
JBrowse link
G Ufsp1 UFM1-specific peptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of UFSP1 mRNA CTD PMID:36139627 NCBI chr12:25,042,882...25,043,896
Ensembl chr12:25,042,116...25,044,087
JBrowse link
G Uhrf2 ubiquitin like with PHD and ring finger domains 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of UHRF2 mRNA CTD PMID:36139627 NCBI chr 1:237,224,050...237,291,406
Ensembl chr 1:237,228,456...237,292,353
JBrowse link
G Upk1a uroplakin 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of UPK1A mRNA CTD PMID:36139627 NCBI chr 1:94,987,110...94,998,083
Ensembl chr 1:94,987,108...94,997,787
JBrowse link
G Upk3b uroplakin 3B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of UPK3B mRNA CTD PMID:36139627 NCBI chr12:26,266,838...26,274,240
Ensembl chr12:26,266,838...26,274,240
JBrowse link
G Ush1g USH1 protein network component sans multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of USH1G mRNA CTD PMID:36139627 NCBI chr10:101,055,923...101,062,753
Ensembl chr10:101,057,208...101,062,564
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of VDR mRNA CTD PMID:36139627 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of VEPH1 mRNA CTD PMID:36139627 NCBI chr 2:152,592,648...152,847,566
Ensembl chr 2:152,601,680...152,847,318
JBrowse link
G Vgf VGF nerve growth factor inducible multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of VGF mRNA CTD PMID:36139627 NCBI chr12:25,274,004...25,281,803
Ensembl chr12:25,273,333...25,282,703
JBrowse link
G Vtn vitronectin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of VTN mRNA CTD PMID:36139627 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860
JBrowse link
G Wasf3 WASP family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WASF3 mRNA CTD PMID:36139627 NCBI chr12:13,675,642...13,774,648
Ensembl chr12:13,675,645...13,774,559
JBrowse link
G Wfdc21 WAP four-disulfide core domain 21 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of WFDC21P mRNA CTD PMID:36139627 NCBI chr10:69,125,336...69,131,205
Ensembl chr10:69,125,320...69,131,201
JBrowse link
G Wnt10b Wnt family member 10B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT10B mRNA CTD PMID:36139627 NCBI chr 7:131,801,046...131,806,850
Ensembl chr 7:131,801,046...131,806,850
JBrowse link
G Wnt11 Wnt family member 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT11 mRNA CTD PMID:36139627 NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660
JBrowse link
G Wnt2b Wnt family member 2B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT2B mRNA CTD PMID:36139627 NCBI chr 2:195,142,573...195,156,945
Ensembl chr 2:195,135,176...195,157,144
JBrowse link
G Wnt4 Wnt family member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of WNT4 mRNA CTD PMID:36139627 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128
JBrowse link
G Wnt7b Wnt family member 7B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of WNT7B mRNA CTD PMID:36139627 NCBI chr 7:118,514,684...118,559,316
Ensembl chr 7:118,514,684...118,559,316
JBrowse link
G Wnt8b Wnt family member 8B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT8B mRNA CTD PMID:36139627 NCBI chr 1:253,303,369...253,325,224
Ensembl chr 1:253,295,557...253,325,224
JBrowse link
G Xaf1 XIAP associated factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of XAF1 mRNA CTD PMID:36139627 NCBI chr10:57,415,935...57,428,348
Ensembl chr10:57,415,658...57,428,349
JBrowse link
G Zc3h6 zinc finger CCCH type containing 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ZC3H6 mRNA CTD PMID:36139627 NCBI chr 3:136,656,116...136,717,560
Ensembl chr 3:136,657,414...136,706,504
JBrowse link
G Zfp608 zinc finger protein 608 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ZNF608 mRNA CTD PMID:36139627 NCBI chr18:50,503,043...50,611,019
Ensembl chr18:50,503,045...50,608,622
JBrowse link
G Zwint ZW10 interacting kinetochore protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ZWINT mRNA CTD PMID:36139627 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
JBrowse link

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  CHEBI ontology 20874
    role 20844
      application 20572
        pharmaceutical 20359
          drug 20359
            antineoplastic agent 18082
              sotorasib 607
Path 2
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  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            heteroorganic entity 20201
                              organochalcogen compound 19822
                                organooxygen compound 19713
                                  carboxamide 17697
                                    alpha,beta-unsaturated carboxylic acid amide 7287
                                      enamide 7287
                                        acrylamides 6534
                                          sotorasib 607
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