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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sotorasib
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Accession:CHEBI:178199 term browser browse the term
Definition:A pyridopyrimidine that is pyrido[2,3-d]pyrimidin-2(1H)-one substituted by 4-methyl-2-(propan-2-yl)pyridin-3-yl, (2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl, fluoro and 2-fluoro-6-hydroxyphenyl groups at positions 1, 4, 6 and 7, respectively. It is approved for the treatment of patients with non-small cell lung cancer having KRAS(G12C) mutations.
Synonyms:exact_synonym: 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one
 related_synonym: AMG-510;   AMG510;   Formula=C30H30F2N6O3;   InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1;   InChIKey=NXQKSXLFSAEQCZ-SFHVURJKSA-N;   Lumakras;   SMILES=CC(C)C1=NC=CC(C)=C1N1C(=O)N=C(N2CCN(C[C@@H]2C)C(=O)C=C)C2=C1N=C(C(F)=C2)C1=C(F)C=CC=C1O;   sotorasibum
 xref: CAS:2296729-00-3;   Chemspider:72380148;   DrugBank:DB15569;   KEGG:D12055
 xref_mesh: MESH:C000706028
 xref: PMID:31189530;   PMID:31666701;   PMID:31820981;   PMID:32540954;   PMID:32686745;   PMID:32955176;   PMID:33283304;   PMID:33466360;   PMID:33547148;   PMID:33957355;   PMID:33971321;   PMID:34004237;   PMID:34043291;   PMID:34094546;   PMID:34096690;   PMID:34137282;   PMID:34140669;   PMID:34144959;   PMID:34158284;   PMID:34219153;   PMID:34301758;   PMID:34357500;   PMID:34359807;   Wikipedia:Sotorasib


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sotorasib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4921524L21Rikl1 RIKEN cDNA 4921524L21 gene like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCDC144BP mRNA CTD PMID:36139627 NCBI chr17:54,808,184...54,847,675
Ensembl chr17:54,808,184...54,847,671
Ensembl chr17:54,808,184...54,847,671 		JBrowse link
G Aadat aminoadipate aminotransferase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AADAT mRNA CTD PMID:36139627 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Abhd11 abhydrolase domain containing 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ABHD11 mRNA CTD PMID:36139627 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACHE mRNA CTD PMID:36139627 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acp7 acid phosphatase 7, tartrate resistant multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACP7 mRNA CTD PMID:36139627 NCBI chr 1:83,896,485...83,923,436
Ensembl chr 1:83,898,153...83,920,634 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACSL5 mRNA CTD PMID:36139627 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACSM3 mRNA CTD PMID:36139627 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACTA2 mRNA CTD PMID:36139627 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actbl2 actin, beta-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ACTBL2 mRNA CTD PMID:36139627 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767 		JBrowse link
G Acy3 aminoacylase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACY3 mRNA CTD PMID:36139627 NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADAMTS1 mRNA CTD PMID:36139627 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADAMTS16 mRNA CTD PMID:36139627 NCBI chr 1:32,430,436...32,562,481
Ensembl chr 1:32,430,436...32,560,494 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADAMTS4 mRNA CTD PMID:36139627 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065 		JBrowse link
G Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ADAMTS6 mRNA CTD PMID:36139627 NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADGRG1 mRNA CTD PMID:36139627 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ADGRL3 mRNA CTD PMID:36139627 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ADRB2 mRNA CTD PMID:36139627 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Afap1l1 actin filament associated protein 1-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AFAP1L1 mRNA CTD PMID:36139627 NCBI chr18:55,183,786...55,244,174
Ensembl chr18:55,183,786...55,244,146 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AGR2 mRNA CTD PMID:36139627 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Akap5 A-kinase anchoring protein 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AKAP5 mRNA CTD PMID:36139627 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Akna AT-hook transcription factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AKNA mRNA CTD PMID:36139627 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AKT3 mRNA CTD PMID:36139627 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ALDH1A2 mRNA CTD PMID:36139627 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ALDOC mRNA CTD PMID:36139627 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Aloxe3 arachidonate epidermal lipoxygenase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ALOXE3 mRNA CTD PMID:36139627 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Alpg alkaline phosphatase, germ cell multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ALPG mRNA CTD PMID:36139627 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836 		JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AMN1 mRNA CTD PMID:36139627 NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AMPD3 mRNA CTD PMID:36139627 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887 		JBrowse link
G Ang angiogenin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANG mRNA CTD PMID:36139627 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANGPTL4 mRNA CTD PMID:36139627 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ank3 ankyrin 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANK3 mRNA CTD PMID:36139627 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Ankef1 ankyrin repeat and EF-hand domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ANKEF1 mRNA CTD PMID:36139627 NCBI chr 3:123,847,832...123,883,060
Ensembl chr 3:123,847,817...123,883,059 		JBrowse link
G Ankrd2 ankyrin repeat domain 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ANKRD2 mRNA CTD PMID:36139627 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Ankrd24 ankyrin repeat domain 24 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANKRD24 mRNA CTD PMID:36139627 NCBI chr 7:8,061,634...8,081,142
Ensembl chr 7:8,061,953...8,081,142 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANKRD37 mRNA CTD PMID:36139627 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963 		JBrowse link
G Ankrd65 ankyrin repeat domain 65 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ANKRD65 mRNA CTD PMID:36139627 NCBI chr 5:166,398,359...166,400,616
Ensembl chr 5:166,397,748...166,400,953 		JBrowse link
G Ano7 anoctamin 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANO7 mRNA CTD PMID:36139627 NCBI chr 9:93,917,524...93,945,323
Ensembl chr 9:93,917,524...93,945,323 		JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANPEP mRNA CTD PMID:36139627 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of AOC3 mRNA CTD PMID:36139627 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Apln apelin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of APLN mRNA CTD PMID:36139627 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apobr apolipoprotein B receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of APOBR mRNA CTD PMID:36139627 NCBI chr 1:181,169,019...181,173,206
Ensembl chr 1:181,168,916...181,173,528 		JBrowse link
G Arfgef3 ARFGEF family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARFGEF3 mRNA CTD PMID:36139627 NCBI chr 1:13,245,578...13,404,319
Ensembl chr 1:13,244,830...13,404,084 		JBrowse link
G Arhgap31 Rho GTPase activating protein 31 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARHGAP31 mRNA CTD PMID:36139627 NCBI chr11:62,038,635...62,151,564
Ensembl chr11:62,038,635...62,151,564 		JBrowse link
G Arhgap8 Rho GTPase activating protein 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARHGAP8 mRNA CTD PMID:36139627 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093 		JBrowse link
G Armh1 armadillo-like helical domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ARMH1 mRNA CTD PMID:36139627 NCBI chr 5:130,680,955...130,722,062
Ensembl chr 5:130,682,485...130,722,062 		JBrowse link
G Atg9b autophagy related 9B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATG9B mRNA CTD PMID:36139627 NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651 		JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ATP10D mRNA CTD PMID:36139627 NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564 		JBrowse link
G Atp13a3 ATPase 13A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATP13A3 mRNA CTD PMID:36139627 NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATP2A3 mRNA CTD PMID:36139627 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ATP6V0D2 mRNA CTD PMID:36139627 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Avil advillin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of AVIL mRNA CTD PMID:36139627 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Bach2 BTB domain and CNC homolog 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BACH2 mRNA CTD PMID:36139627 NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BAMBI mRNA CTD PMID:36139627 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Barx2 BARX homeobox 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BARX2 mRNA CTD PMID:36139627 NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013 		JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BATF3 mRNA CTD PMID:36139627 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139 		JBrowse link
G Bcl2l14 Bcl2-like 14 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BCL2L14 mRNA CTD PMID:36139627 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086 		JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BCO2 mRNA CTD PMID:36139627 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Bex1 brain expressed X-linked 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BEX2 mRNA CTD PMID:36139627 NCBI chr  X:99,219,014...99,220,518
Ensembl chr  X:99,219,014...99,220,958 		JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BICDL2 mRNA CTD PMID:36139627 NCBI chr10:12,691,610...12,700,049
Ensembl chr10:12,691,610...12,700,049 		JBrowse link
G Bin2 bridging integrator 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BIN2 mRNA CTD PMID:36139627 NCBI chr 7:131,742,001...131,768,208
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G Blacat1 BLACAT1 overlapping LEMD1 locus multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BLACAT1 mRNA CTD PMID:36139627
G Blnk B-cell linker multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BLNK mRNA CTD PMID:36139627 NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of BMP6 mRNA CTD PMID:36139627 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Borcs8 BLOC-1 related complex subunit 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BORCS8 mRNA CTD PMID:36139627 NCBI chr16:19,274,305...19,280,969
Ensembl chr16:19,274,023...19,280,339 		JBrowse link
G Btc betacellulin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BTC mRNA CTD PMID:36139627 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of BTG2 mRNA CTD PMID:36139627 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C13h1orf116 similar to human chromosome 1 open reading frame 116 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of C1ORF116 mRNA CTD PMID:36139627 NCBI chr13:42,187,442...42,201,432
Ensembl chr13:42,188,609...42,201,426 		JBrowse link
G C14h7orf57 similar to human chromosome 7 open reading frame 57 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of C7ORF57 mRNA CTD PMID:36139627 NCBI chr14:83,748,478...83,768,293
Ensembl chr14:83,748,478...83,767,435 		JBrowse link
G C1r complement C1r multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C1R mRNA CTD PMID:36139627 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C1s complement C1s multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C1S mRNA CTD PMID:36139627 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303 		JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C15ORF48 mRNA CTD PMID:36139627 NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006 		JBrowse link
G C7 complement C7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C7 mRNA CTD PMID:36139627 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CACNA1D mRNA CTD PMID:36139627 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CACNA1F mRNA CTD PMID:36139627 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CACNB4 mRNA CTD PMID:36139627 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Calb2 calbindin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CALB2 mRNA CTD PMID:36139627 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Capn12 calpain 12 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CAPN12 mRNA CTD PMID:36139627 NCBI chr 1:84,171,059...84,183,161
Ensembl chr 1:84,171,059...84,183,119 		JBrowse link
G Capn8 calpain 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CAPN8 mRNA CTD PMID:36139627 NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146 		JBrowse link
G Car9 carbonic anhydrase 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CA9 mRNA CTD PMID:36139627 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CASP1 mRNA CTD PMID:36139627 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO sotorasib results in increased cleavage of CASP3 protein CTD PMID:31666701 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Catspere catsper channel auxiliary subunit epsilon multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CATSPERE mRNA CTD PMID:36139627 NCBI chr13:89,799,669...89,954,723
Ensembl chr13:89,819,244...89,950,979 		JBrowse link
G Ccdc110 coiled-coil domain containing 110 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCDC110 mRNA CTD PMID:36139627 NCBI chr16:46,315,745...46,337,050
Ensembl chr16:46,315,745...46,337,021 		JBrowse link
G Ccdc87 coiled-coil domain containing 87 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCDC87 mRNA CTD PMID:36139627 NCBI chr 1:202,135,021...202,137,717
Ensembl chr 1:202,134,963...202,138,337 		JBrowse link
G Ccdc89 coiled-coil domain containing 89 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCDC89 mRNA CTD PMID:36139627 NCBI chr 1:144,386,252...144,387,514
Ensembl chr 1:144,386,158...144,389,850 		JBrowse link
G Ccdc96 coiled-coil domain containing 96 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CFAP184 mRNA CTD PMID:36139627 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCL22 mRNA CTD PMID:36139627 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccm2l CCM2 like scaffold protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCM2L mRNA CTD PMID:36139627 NCBI chr 3:141,533,470...141,549,136
Ensembl chr 3:141,533,511...141,549,140 		JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CCNE2 mRNA CTD PMID:36139627 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CCR1 mRNA CTD PMID:36139627 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd22 CD22 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CD22 mRNA CTD PMID:36139627 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CD274 mRNA CTD PMID:36139627 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd72 Cd72 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CD72 mRNA CTD PMID:36139627 NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725 		JBrowse link
G Cd74 CD74 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CD74 mRNA CTD PMID:36139627 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cd82 Cd82 molecule multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CD82 mRNA CTD PMID:36139627 NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809 		JBrowse link
G Cdcp1 CUB domain containing protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDCP1 mRNA CTD PMID:36139627 NCBI chr 8:122,828,685...122,865,345
Ensembl chr 8:122,828,685...122,865,388 		JBrowse link
G Cdh15 cadherin 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDH15 mRNA CTD PMID:36139627 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105 		JBrowse link
G Cdh3 cadherin 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDH3 mRNA CTD PMID:36139627 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CDKN1A mRNA CTD PMID:36139627 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CDKN1C mRNA CTD PMID:36139627 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cenps centromere protein S multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CENPS mRNA CTD PMID:36139627 NCBI chr 5:159,563,917...159,573,534 JBrowse link
G Cfap45 cilia and flagella associated protein 45 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CFAP45 mRNA CTD PMID:36139627 NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878 		JBrowse link
G Cfap92 cilia and flagella associated protein 92 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CFAP92 mRNA CTD PMID:36139627 NCBI chr 4:120,126,565...120,181,575
Ensembl chr 4:120,126,567...120,181,546 		JBrowse link
G Cfap96 cilia and flagella associated protein 96 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CFAP96 mRNA CTD PMID:36139627 NCBI chr16:46,291,075...46,315,616
Ensembl chr16:46,291,311...46,315,625 		JBrowse link
G Cfh complement factor H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CFH mRNA CTD PMID:36139627 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CHD7 mRNA CTD PMID:36139627 NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358 		JBrowse link
G Chd9nb CHD9 neighbor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHD9NB mRNA CTD PMID:36139627
G Chgb chromogranin B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHGB mRNA CTD PMID:36139627 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CHRM4 mRNA CTD PMID:36139627 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHRNA10 mRNA CTD PMID:36139627 NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476 		JBrowse link
G Ciart circadian associated repressor of transcription multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CIART mRNA CTD PMID:36139627 NCBI chr 2:183,419,819...183,424,845
Ensembl chr 2:183,419,819...183,423,313 		JBrowse link
G Cimip2a ciliary microtubule inner protein 2A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CIMIP2A mRNA CTD PMID:36139627 NCBI chr 3:8,030,548...8,038,370
Ensembl chr 3:8,033,246...8,037,961 		JBrowse link
G Cldn9 claudin 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CLDN9 mRNA CTD PMID:36139627 NCBI chr10:12,714,137...12,715,568 JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CNIH2 mRNA CTD PMID:36139627 NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089 		JBrowse link
G Col13a1 collagen type XIII alpha 1 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of COL13A1 mRNA CTD PMID:36139627 NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COL1A2 mRNA CTD PMID:36139627 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col5a3 collagen type V alpha 3 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COL5A3 mRNA CTD PMID:36139627 NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of COL6A3 mRNA CTD PMID:36139627 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Col9a2 collagen type IX alpha 2 chain multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COL9A2 mRNA CTD PMID:36139627 NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of COLQ mRNA CTD PMID:36139627 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107 		JBrowse link
G Cpe carboxypeptidase E multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CPE mRNA CTD PMID:36139627 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cracr2b calcium release activated channel regulator 2B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CRACR2B mRNA CTD PMID:36139627 NCBI chr 1:196,558,407...196,563,961
Ensembl chr 1:196,558,588...196,563,771 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CREB3L1 mRNA CTD PMID:36139627 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CREB3L3 mRNA CTD PMID:36139627 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048 		JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CREG2 mRNA CTD PMID:36139627 NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095 		JBrowse link
G Crybg1 crystallin beta-gamma domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CRYBG1 mRNA CTD PMID:36139627 NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392 		JBrowse link
G Crym crystallin, mu multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CRYM mRNA CTD PMID:36139627 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CSAD mRNA CTD PMID:36139627 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CSF3 mRNA CTD PMID:36139627 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ctsc cathepsin C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CTSC mRNA CTD PMID:36139627 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsl cathepsin L multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CTSL mRNA CTD PMID:36139627 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Ctso cathepsin O multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CTSO mRNA CTD PMID:36139627 NCBI chr 2:167,230,407...167,254,761
Ensembl chr 2:167,230,330...167,253,702 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CX3CL1 mRNA CTD PMID:36139627 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO sotorasib results in increased expression of CXCL10 mRNA CTD PMID:31666701 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO sotorasib results in increased expression of CXCL11 mRNA CTD PMID:31666701 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CYP26B1 mRNA CTD PMID:36139627 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DDIT4L mRNA CTD PMID:36139627 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DDX60 mRNA CTD PMID:36139627 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dennd3 DENN domain containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DENND3 mRNA CTD PMID:36139627 NCBI chr 7:105,415,870...105,473,583
Ensembl chr 7:105,415,677...105,473,592 		JBrowse link
G Depp1 DEPP autophagy regulator 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DEPP1 mRNA CTD PMID:36139627 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DEPTOR mRNA CTD PMID:36139627 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DHRS2 mRNA CTD PMID:36139627 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DIO2 mRNA CTD PMID:36139627 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DKK3 mRNA CTD PMID:36139627 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DLC1 mRNA CTD PMID:36139627 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dmkn dermokine multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DMKN mRNA CTD PMID:36139627 NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006 		JBrowse link
G Dnaaf8 dynein axonemal assembly factor 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DNAAF8 mRNA CTD PMID:36139627 NCBI chr10:10,600,747...10,614,891
Ensembl chr10:10,600,734...10,614,891 		JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DNAH11 mRNA CTD PMID:36139627 NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536 		JBrowse link
G Doc2b double C2 domain beta multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DOC2B mRNA CTD PMID:36139627 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267 		JBrowse link
G Dok3 docking protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DOK3 mRNA CTD PMID:36139627 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188 		JBrowse link
G Drc3 dynein regulatory complex subunit 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DRC3 mRNA CTD PMID:36139627 NCBI chr10:45,149,094...45,200,659
Ensembl chr10:45,157,354...45,199,369 		JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of DUOX1 mRNA CTD PMID:36139627 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUOX2 mRNA CTD PMID:36139627 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Duoxa1 dual oxidase maturation factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUOXA1 mRNA CTD PMID:36139627 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUSP4 mRNA CTD PMID:36139627 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUSP5 mRNA CTD PMID:36139627 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of DUSP6 mRNA CTD PMID:36139627 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G E2f2 E2F transcription factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of E2F2 mRNA CTD PMID:36139627 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G E2f7 E2F transcription factor 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of E2F7 mRNA CTD PMID:36139627 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EFEMP2 mRNA CTD PMID:36139627 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
G Efna3 ephrin A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EFNA3 mRNA CTD PMID:36139627 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of EGF mRNA CTD PMID:36139627 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation ISO sotorasib results in increased phosphorylation of EGFR protein CTD PMID:31666701 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif4e3 eukaryotic translation initiation factor 4E family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EIF4E3 mRNA CTD PMID:36139627 NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ELF5 mRNA CTD PMID:36139627 NCBI chr 3:89,808,837...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Elmod1 ELMO domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ELMOD1 mRNA CTD PMID:36139627 NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140 		JBrowse link
G Eno2 enolase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ENO2 mRNA CTD PMID:36139627 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Eno4 enolase 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ENO4 mRNA CTD PMID:36139627 NCBI chr 1:258,096,406...258,119,811
Ensembl chr 1:258,096,432...258,128,984 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ENPP1 mRNA CTD PMID:36139627 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ENTPD2 mRNA CTD PMID:36139627 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPAS1 mRNA CTD PMID:36139627 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPHA3 mRNA CTD PMID:36139627 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Epha8 Eph receptor A8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPHA8 mRNA CTD PMID:36139627 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Eppk1 epiplakin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPPK1 mRNA CTD PMID:36139627 NCBI chr 7:107,816,919...107,842,946
Ensembl chr 7:107,817,693...107,831,159 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ERAP1 mRNA CTD PMID:36139627 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447 		JBrowse link
G Erfl ETS repressor factor like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ERFL mRNA CTD PMID:36139627 NCBI chr 1:80,521,378...80,526,262
Ensembl chr 1:80,521,854...80,526,262 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ERO1A mRNA CTD PMID:36139627 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ESRP1 mRNA CTD PMID:36139627 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062 		JBrowse link
G Etv2 ETS variant transcription factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ETV2 mRNA CTD PMID:36139627 NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431 		JBrowse link
G Etv4 ETS variant transcription factor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ETV4 mRNA CTD PMID:36139627 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G Evi2a ecotropic viral integration site 2A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EVI2A mRNA CTD PMID:36139627 NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843 		JBrowse link
G Exoc3l1 exocyst complex component 3-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of EXOC3L1 mRNA CTD PMID:36139627 NCBI chr19:33,166,836...33,174,371
Ensembl chr19:33,166,837...33,172,486 		JBrowse link
G Exoc3l4 exocyst complex component 3-like 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of EXOC3L4 mRNA CTD PMID:36139627 NCBI chr 6:130,452,680...130,466,684
Ensembl chr 6:130,452,661...130,466,683 		JBrowse link
G Exph5 exophilin 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EXPH5 mRNA CTD PMID:36139627 NCBI chr 8:53,698,825...53,775,371
Ensembl chr 8:53,698,852...53,773,169 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of F2RL1 mRNA CTD PMID:36139627 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fam107b family with sequence similarity 107, member B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FAM107B mRNA CTD PMID:36139627 NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989 		JBrowse link
G Fam186b family with sequence similarity 186, member B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FAM186B mRNA CTD PMID:36139627 NCBI chr 7:130,408,830...130,424,261
Ensembl chr 7:130,408,830...130,424,261 		JBrowse link
G Fam241a family with sequence similarity 241 member A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FAM241A mRNA CTD PMID:36139627 NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242 		JBrowse link
G Fat2 FAT atypical cadherin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FAT2 mRNA CTD PMID:36139627 NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216 		JBrowse link
G Fbxo36 F-box protein 36 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FBXO36 mRNA CTD PMID:36139627 NCBI chr 9:86,042,522...86,107,220
Ensembl chr 9:86,040,862...86,107,229 		JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FDXR mRNA CTD PMID:36139627 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FGF19 mRNA CTD PMID:36139627 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fhip1a FHF complex subunit HOOK interacting protein 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FHIP1A mRNA CTD PMID:36139627 NCBI chr 2:171,016,951...171,265,715
Ensembl chr 2:171,021,246...171,265,848 		JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FLACC1 mRNA CTD PMID:36139627 NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648 		JBrowse link
G Flnc filamin C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FLNC mRNA CTD PMID:36139627 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Fmn1 formin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FMN1 mRNA CTD PMID:36139627 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220 		JBrowse link
G Fndc11 fibronectin type III domain containing 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FNDC11 mRNA CTD PMID:36139627 NCBI chr 3:168,330,607...168,333,111
Ensembl chr 3:168,330,602...168,334,617 		JBrowse link
G Foxd4 forkhead box D4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FOXD4 mRNA CTD PMID:36139627 NCBI chr 1:222,557,494...222,559,189
Ensembl chr 1:222,557,360...222,559,159 		JBrowse link
G Foxq1 forkhead box Q1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FOXQ1 mRNA CTD PMID:36139627 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 		JBrowse link
G Frmd4b FERM domain containing 4B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FRMD4B mRNA CTD PMID:36139627 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FSCN1 mRNA CTD PMID:36139627 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fut11 fucosyltransferase 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FUT11 mRNA CTD PMID:36139627 NCBI chr15:3,598,768...3,602,328
Ensembl chr15:3,598,758...3,602,356 		JBrowse link
G Fyb2 FYN binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FYB2 mRNA CTD PMID:36139627 NCBI chr 5:119,677,116...119,800,911
Ensembl chr 5:119,677,204...119,800,910 		JBrowse link
G Gab2 GRB2-associated binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAB2 mRNA CTD PMID:36139627 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAD1 mRNA CTD PMID:36139627 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAL3ST1 mRNA CTD PMID:36139627 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GALNT7 mRNA CTD PMID:36139627 NCBI chr16:32,578,643...32,703,189
Ensembl chr16:32,578,690...32,702,690 		JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GAS6 mRNA CTD PMID:36139627 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gask1b golgi associated kinase 1B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GASK1B mRNA CTD PMID:36139627 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477 		JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GBP2 mRNA CTD PMID:36139627 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gckr glucokinase regulator multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GCKR mRNA CTD PMID:36139627 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GCNT3 mRNA CTD PMID:36139627 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GDAP1 mRNA CTD PMID:36139627 NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061 		JBrowse link
G Ghr growth hormone receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GHR mRNA CTD PMID:36139627 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Gipc3 GIPC PDZ domain containing family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GIPC3 mRNA CTD PMID:36139627 NCBI chr 7:8,374,941...8,383,281 JBrowse link
G Gipr gastric inhibitory polypeptide receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GIPR mRNA CTD PMID:36139627 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462 		JBrowse link
G Gjb3 gap junction protein, beta 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GJB3 mRNA CTD PMID:36139627 NCBI chr 5:139,649,227...139,654,970
Ensembl chr 5:139,649,195...139,654,980 		JBrowse link
G Gjb4 gap junction protein, beta 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GJB4 mRNA CTD PMID:36139627 NCBI chr 5:139,675,776...139,679,551
Ensembl chr 5:139,675,780...139,679,667 		JBrowse link
G Gldc glycine decarboxylase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GLDC mRNA CTD PMID:36139627 NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097 		JBrowse link
G Glul glutamate-ammonia ligase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GLUL mRNA CTD PMID:36139627 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GPNMB mRNA CTD PMID:36139627 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr146 G protein-coupled receptor 146 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GPR146 mRNA CTD PMID:36139627 NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GPR37L1 mRNA CTD PMID:36139627 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421 		JBrowse link
G Gpr39 G protein-coupled receptor 39 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GPR39 mRNA CTD PMID:36139627 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Gpr87 G protein-coupled receptor 87 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GPR87 mRNA CTD PMID:36139627 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190 		JBrowse link
G Gramd1b GRAM domain containing 1B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GRAMD1B mRNA CTD PMID:36139627 NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925 		JBrowse link
G Grb7 growth factor receptor bound protein 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GRB7 mRNA CTD PMID:36139627 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GRIN2D mRNA CTD PMID:36139627 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Gsdmc gasdermin C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GSDMC mRNA CTD PMID:36139627 NCBI chr 7:95,594,015...95,606,106
Ensembl chr 7:95,594,015...95,611,344 		JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GTF2IRD2 mRNA CTD PMID:36139627 NCBI chr12:22,497,767...22,536,455
Ensembl chr12:22,498,091...22,536,263 		JBrowse link
G Guca1b guanylate cyclase activator 1B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GUCA1B mRNA CTD PMID:36139627 NCBI chr 9:13,599,619...13,607,455
Ensembl chr 9:13,599,619...13,607,455 		JBrowse link
G H1f2 H1.2 linker histone, cluster member multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of H1-2 mRNA CTD PMID:36139627 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G Hal histidine ammonia lyase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HAL mRNA CTD PMID:36139627 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HAPLN2 mRNA CTD PMID:36139627 NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588 		JBrowse link
G Has3 hyaluronan synthase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HAS3 mRNA CTD PMID:36139627 NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HBEGF mRNA CTD PMID:36139627 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HECW2 mRNA CTD PMID:36139627 NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:55,365,203...55,580,327 		JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HERC6 mRNA CTD PMID:36139627 NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HEY1 mRNA CTD PMID:36139627 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HEYL mRNA CTD PMID:36139627 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HIC1 mRNA CTD PMID:36139627 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HILPDA mRNA CTD PMID:36139627 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of H2AC11 mRNA CTD PMID:36139627 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of H2AC6 mRNA CTD PMID:36139627 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hivep2 HIVEP zinc finger 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HIVEP2 mRNA CTD PMID:36139627 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993 		JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HK2 mRNA CTD PMID:36139627 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hkdc1 hexokinase domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HKDC1 mRNA CTD PMID:36139627 NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HOGA1 mRNA CTD PMID:36139627 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568 		JBrowse link
G Hoxa13 homeo box A13 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HOXA13 mRNA CTD PMID:36139627 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
G Hoxb9 homeo box B9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HOXB9 mRNA CTD PMID:36139627 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818 		JBrowse link
G Hoxc4 homeo box C4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HOXC4 mRNA CTD PMID:36139627 NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133 		JBrowse link
G Hpcal4 hippocalcin-like 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HPCAL4 mRNA CTD PMID:36139627 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416 		JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HS3ST3B1 mRNA CTD PMID:36139627 NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970 		JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HSD17B14 mRNA CTD PMID:36139627 NCBI chr 1:96,029,224...96,039,577
Ensembl chr 1:96,029,284...96,039,883 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HSPA1A mRNA CTD PMID:36139627 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Htra1 HtrA serine peptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HTRA1 mRNA CTD PMID:36139627 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Hunk hormonally upregulated Neu-associated kinase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HUNK mRNA CTD PMID:36139627 NCBI chr11:29,641,122...29,758,392
Ensembl chr11:29,640,775...29,757,526 		JBrowse link
G Hyal1 hyaluronidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HYAL1 mRNA CTD PMID:36139627 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Ifi35 interferon-induced protein 35 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of IFI35 mRNA CTD PMID:36139627 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Ifnlr1 interferon, lambda receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IFNLR1 mRNA CTD PMID:36139627 NCBI chr 5:147,919,547...147,942,328
Ensembl chr 5:147,919,908...147,942,332 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IGF2BP3 mRNA CTD PMID:36139627 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IGFBP1 mRNA CTD PMID:36139627 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IL1B mRNA CTD PMID:36139627 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IL1RAPL1 mRNA CTD PMID:36139627 NCBI chr  X:51,371,969...52,876,726
Ensembl chr  X:51,378,215...52,876,772 		JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IL6R mRNA CTD PMID:36139627 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Inka1 inka box actin regulator 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of INKA1 mRNA CTD PMID:36139627 NCBI chr 8:108,674,263...108,675,953
Ensembl chr 8:108,674,263...108,675,953 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of INPP5D mRNA CTD PMID:36139627 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Insyn1 inhibitory synaptic factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of INSYN1 mRNA CTD PMID:36139627 NCBI chr 8:58,904,153...58,914,850
Ensembl chr 8:58,904,153...58,914,843 		JBrowse link
G Iqank1 IQ motif and ankyrin repeat containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IQANK1 mRNA CTD PMID:36139627 NCBI chr 7:107,724,962...107,759,163
Ensembl chr 7:107,724,997...107,759,162 		JBrowse link
G Iqcn IQ motif containing N multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of IQCN mRNA CTD PMID:36139627 NCBI chr16:18,716,519...18,733,971
Ensembl chr16:18,716,519...18,726,261 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of IRAK2 mRNA CTD PMID:36139627 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of IRF1 mRNA CTD PMID:36139627 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Ism2 isthmin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ISM2 mRNA CTD PMID:36139627 NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514 		JBrowse link
G Itga10 integrin subunit alpha 10 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGA10 mRNA CTD PMID:36139627 NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172 		JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGA2 mRNA CTD PMID:36139627 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itgax integrin subunit alpha X multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGAX mRNA CTD PMID:36139627 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698 		JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGB3 mRNA CTD PMID:36139627 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itgb4 integrin subunit beta 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGB4 mRNA CTD PMID:36139627 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012 		JBrowse link
G Jak3 Janus kinase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of JAK3 mRNA CTD PMID:36139627 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Jam2 junctional adhesion molecule 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of JAM2 mRNA CTD PMID:36139627 NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KCNJ4 mRNA CTD PMID:36139627 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151 		JBrowse link
G Kcnk5 potassium two pore domain channel subfamily K member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KCNK5 mRNA CTD PMID:36139627 NCBI chr15:4,122,442...4,164,718
Ensembl chr15:4,122,442...4,164,718 		JBrowse link
G Kdm7a lysine demethylase 7A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KDM7A mRNA CTD PMID:36139627 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Kiaa1755 KIAA1755 ortholog multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KIAA1755 mRNA CTD PMID:36139627 NCBI chr 3:146,850,558...146,884,238
Ensembl chr 3:146,850,557...146,884,871 		JBrowse link
G Kif17 kinesin family member 17 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KIF17 mRNA CTD PMID:36139627 NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638 		JBrowse link
G Klf7 KLF transcription factor 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KLF7 mRNA CTD PMID:36139627 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261 		JBrowse link
G Klhdc7a kelch domain containing 7A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KLHDC7A mRNA CTD PMID:36139627 NCBI chr 5:152,218,604...152,224,707
Ensembl chr 5:152,221,033...152,224,551 		JBrowse link
G Klhdc7b kelch domain containing 7B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KLHDC7B mRNA CTD PMID:36139627 NCBI chr 7:120,452,081...120,455,737
Ensembl chr 7:120,453,932...120,455,737 		JBrowse link
G Kras KRAS proto-oncogene, GTPase increases response to substance
affects binding
multiple interactions		 ISO KRAS protein mutant form results in increased susceptibility to sotorasib
sotorasib binds to KRAS protein mutant form
KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK1 protein]; KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK3 protein]		 CTD PMID:31666701 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt15 keratin 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KRT15 mRNA CTD PMID:36139627 NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt7 keratin 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KRT7 mRNA CTD PMID:36139627 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Krt86 keratin 86 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of KRT86 mRNA CTD PMID:36139627 NCBI chr 7:132,591,489...132,598,142
Ensembl chr 7:132,591,545...132,598,021 		JBrowse link
G Lad1 ladinin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAD1 mRNA CTD PMID:36139627 NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967 		JBrowse link
G Lama2 laminin subunit alpha 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAMA2 mRNA CTD PMID:36139627 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lama4 laminin subunit alpha 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAMA4 mRNA CTD PMID:36139627 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347 		JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LAMC2 mRNA CTD PMID:36139627 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LAPTM5 mRNA CTD PMID:36139627 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LAT2 mRNA CTD PMID:36139627 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LCP1 mRNA CTD PMID:36139627 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLR mRNA CTD PMID:36139627 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Ldlrad1 low density lipoprotein receptor class A domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLRAD1 mRNA CTD PMID:36139627 NCBI chr 5:121,984,245...122,000,941
Ensembl chr 5:121,991,690...122,000,944 		JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LDLRAD4 mRNA CTD PMID:36139627 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238 		JBrowse link
G Lemd1 LEM domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LEMD1 mRNA CTD PMID:36139627 NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948 		JBrowse link
G Lgals9 galectin 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LGALS9 mRNA CTD PMID:36139627 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lgi3 leucine-rich repeat LGI family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LGI3 mRNA CTD PMID:36139627 NCBI chr15:45,605,611...45,612,739
Ensembl chr15:45,605,611...45,612,739 		JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LHX1 mRNA CTD PMID:36139627 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Lhx6 LIM homeobox 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LHX6 mRNA CTD PMID:36139627 NCBI chr 3:19,432,439...19,456,268
Ensembl chr 3:19,433,494...19,456,061 		JBrowse link
G Lipg lipase G, endothelial type multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LIPG mRNA CTD PMID:36139627 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Liph lipase H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LIPH mRNA CTD PMID:36139627 NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625 		JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LONRF3 mRNA CTD PMID:36139627 NCBI chr  X:115,565,214...115,603,886
Ensembl chr  X:115,565,267...115,598,809 		JBrowse link
G Lox lysyl oxidase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LOX mRNA CTD PMID:36139627 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Lratd2 LRAT domain containing 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LRATD2 mRNA CTD PMID:36139627 NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189 		JBrowse link
G Lrrc37a leucine rich repeat containing 37A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LRRC37A3 mRNA CTD PMID:36139627 NCBI chr10:88,395,837...88,433,519
Ensembl chr10:88,396,663...88,433,323 		JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LSR mRNA CTD PMID:36139627 NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LTBP1 mRNA CTD PMID:36139627 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LTBP2 mRNA CTD PMID:36139627 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208 		JBrowse link
G Lyst lysosomal trafficking regulator multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LYST mRNA CTD PMID:36139627 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480 		JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of LZTS1 mRNA CTD PMID:36139627 NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MAD1L1 mRNA CTD PMID:36139627 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MAFF mRNA CTD PMID:36139627 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Map1a microtubule-associated protein 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MAP1A mRNA CTD PMID:36139627 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MAP4K1 mRNA CTD PMID:36139627 NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK1 protein] CTD PMID:31666701 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions		 ISO sotorasib results in decreased phosphorylation of MAPK3 protein
KRAS protein affects the reaction [sotorasib results in decreased phosphorylation of MAPK3 protein]		 CTD PMID:31666701 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Marchf4 membrane associated ring-CH-type finger 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MARCHF4 mRNA CTD PMID:36139627 NCBI chr 9:74,078,437...74,196,070
Ensembl chr 9:74,078,434...74,198,199 		JBrowse link
G Mast4 microtubule associated serine/threonine kinase family member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MAST4 mRNA CTD PMID:36139627 NCBI chr 2:33,893,241...34,483,682
Ensembl chr 2:33,894,436...34,483,723 		JBrowse link
G Matn2 matrilin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MATN2 mRNA CTD PMID:36139627 NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113 		JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MCTP1 mRNA CTD PMID:36139627 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833 		JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MDGA1 mRNA CTD PMID:36139627 NCBI chr20:7,900,327...7,964,309
Ensembl chr20:7,904,358...7,963,471 		JBrowse link
G Meis1 Meis homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MEIS1 mRNA CTD PMID:36139627 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Mest mesoderm specific transcript multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MEST mRNA CTD PMID:36139627 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145 		JBrowse link
G MGC94891 hypothetical protein LOC681210 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of C6ORF118 mRNA CTD PMID:36139627 NCBI chr 1:51,740,328...51,764,041
Ensembl chr 1:51,740,330...51,763,989 		JBrowse link
G Mid1 midline 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MID1 mRNA CTD PMID:36139627 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MILR1 mRNA CTD PMID:36139627 NCBI chr10:91,684,288...91,705,284
Ensembl chr10:91,687,831...91,705,282 		JBrowse link
G Mlph melanophilin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MLPH mRNA CTD PMID:36139627 NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP1 mRNA CTD PMID:36139627 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP12 mRNA CTD PMID:36139627 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP13 mRNA CTD PMID:36139627 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP14 mRNA CTD PMID:36139627 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp19 matrix metallopeptidase 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MMP19 mRNA CTD PMID:36139627 NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP3 mRNA CTD PMID:36139627 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP9 mRNA CTD PMID:36139627 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Morn3 MORN repeat containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MORN3 mRNA CTD PMID:36139627 NCBI chr12:33,505,654...33,529,918
Ensembl chr12:33,514,230...33,529,931 		JBrowse link
G Mpzl2 myelin protein zero-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MPZL2 mRNA CTD PMID:36139627 NCBI chr 8:45,348,285...45,359,298
Ensembl chr 8:45,348,285...45,359,298 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MRAP2 mRNA CTD PMID:36139627 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Muc3a mucin 3A, cell surface associated multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MUC3A mRNA CTD PMID:36139627 NCBI chr12:19,450,679...19,454,753 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MUC5B mRNA CTD PMID:36139627 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250 		JBrowse link
G Mybph myosin binding protein H multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYBPH mRNA CTD PMID:36139627 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893 		JBrowse link
G Myh15 myosin, heavy chain 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYH15 mRNA CTD PMID:36139627 NCBI chr11:51,621,924...51,763,037
Ensembl chr11:51,622,413...51,762,971 		JBrowse link
G Myo10 myosin X multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO10 mRNA CTD PMID:36139627 NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030 		JBrowse link
G Myo15a myosin XVA multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO15A mRNA CTD PMID:36139627 NCBI chr10:45,277,619...45,335,953
Ensembl chr10:45,278,737...45,335,340 		JBrowse link
G Myo15b myosin XVB multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO15B mRNA CTD PMID:36139627 NCBI chr10:101,088,734...101,126,159
Ensembl chr10:101,104,209...101,125,693 		JBrowse link
G Myo5c myosin VC multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MYO5C mRNA CTD PMID:36139627 NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483 		JBrowse link
G Myo7b myosin VIIb multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MYO7B mRNA CTD PMID:36139627 NCBI chr18:23,588,307...23,669,841
Ensembl chr18:23,588,307...23,669,809 		JBrowse link
G N4bp3 Nedd4 binding protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of N4BP3 mRNA CTD PMID:36139627 NCBI chr10:35,898,031...35,906,704
Ensembl chr10:35,899,096...35,907,001 		JBrowse link
G Nav3 neuron navigator 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NAV3 mRNA CTD PMID:36139627 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NDRG1 mRNA CTD PMID:36139627 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Ndrg4 NDRG family member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NDRG4 mRNA CTD PMID:36139627 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NDUFV2 mRNA CTD PMID:36139627 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NEDD9 mRNA CTD PMID:36139627 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nes nestin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NES mRNA CTD PMID:36139627 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NEURL3 mRNA CTD PMID:36139627 NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NGEF mRNA CTD PMID:36139627 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914 		JBrowse link
G Nhsl1 NHS-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NHSL1 mRNA CTD PMID:36139627 NCBI chr 1:12,956,525...13,188,580
Ensembl chr 1:12,956,021...13,187,547 		JBrowse link
G Nhsl2 NHS-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NHSL2 mRNA CTD PMID:36139627 NCBI chr  X:66,969,953...67,209,464
Ensembl chr  X:66,970,151...67,200,911 		JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NIM1K mRNA CTD PMID:36139627 NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762 		JBrowse link
G Nipal4 NIPA-like domain containing 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NIPAL4 mRNA CTD PMID:36139627 NCBI chr10:30,583,926...30,600,640
Ensembl chr10:30,583,926...30,600,640 		JBrowse link
G Nkx2-1 NK2 homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NKX2-1 mRNA CTD PMID:36139627 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nlgn1 neuroligin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NLGN1 mRNA CTD PMID:36139627 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NLRP1 mRNA CTD PMID:36139627 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NMNAT2 mRNA CTD PMID:36139627 NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484 		JBrowse link
G Nog noggin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NOG mRNA CTD PMID:36139627 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Notch4 notch receptor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NOTCH4 mRNA CTD PMID:36139627 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Npas1 neuronal PAS domain protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NPAS1 mRNA CTD PMID:36139627 NCBI chr 1:77,167,375...77,187,887
Ensembl chr 1:77,167,381...77,186,762 		JBrowse link
G Npb neuropeptide B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NPB mRNA CTD PMID:36139627 NCBI chr10:105,883,992...105,887,689
Ensembl chr10:105,874,708...105,887,254 		JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NPR3 mRNA CTD PMID:36139627 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Nptx1 neuronal pentraxin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NPTX1 mRNA CTD PMID:36139627 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NR1D1 mRNA CTD PMID:36139627 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NR3C2 mRNA CTD PMID:36139627 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nrep neuronal regeneration related protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NREP mRNA CTD PMID:36139627 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of NRP1 mRNA CTD PMID:36139627 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrp2 neuropilin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NRP2 mRNA CTD PMID:36139627 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NT5E mRNA CTD PMID:36139627 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Ntsr1 neurotensin receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NTSR1 mRNA CTD PMID:36139627 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Nyap1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NYAP1 mRNA CTD PMID:36139627 NCBI chr12:18,956,192...18,967,624
Ensembl chr12:18,956,268...18,967,543 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of OAS1 mRNA CTD PMID:36139627 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of OAS3 mRNA CTD PMID:36139627 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of OASL mRNA CTD PMID:36139627 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of OBSCN mRNA CTD PMID:36139627 NCBI chr10:43,774,113...43,919,718
Ensembl chr10:43,789,293...43,919,723 		JBrowse link
G Onecut3 one cut homeobox 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ONECUT3 mRNA CTD PMID:36139627 NCBI chr 7:9,199,997...9,219,303
Ensembl chr 7:9,200,035...9,219,158
Ensembl chr 7:9,200,035...9,219,158 		JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of OSGIN1 mRNA CTD PMID:36139627 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516 		JBrowse link
G P2rx6 purinergic receptor P2X 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of P2RX6 mRNA CTD PMID:36139627 NCBI chr11:83,439,922...83,450,449
Ensembl chr11:83,439,924...83,450,481 		JBrowse link
G P3h2 prolyl 3-hydroxylase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of P3H2 mRNA CTD PMID:36139627 NCBI chr11:74,634,267...74,775,422
Ensembl chr11:74,634,267...74,775,421 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PAG1 mRNA CTD PMID:36139627 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Paqr5 progestin and adipoQ receptor family member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PAQR5 mRNA CTD PMID:36139627 NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688 		JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PAQR9 mRNA CTD PMID:36139627 NCBI chr 8:96,114,249...96,116,546 JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PBLD mRNA CTD PMID:36139627 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614 		JBrowse link
G Pcdhb19 protocadherin beta 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PCDHB12 mRNA CTD PMID:36139627 NCBI chr18:29,204,838...29,207,646 JBrowse link
G Pde2a phosphodiesterase 2A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PDE2A mRNA CTD PMID:36139627 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PDP2 mRNA CTD PMID:36139627 NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074 		JBrowse link
G Per1 period circadian regulator 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PER1 mRNA CTD PMID:36139627 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PFKFB4 mRNA CTD PMID:36139627 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634 		JBrowse link
G Pfn4 profilin family, member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PFN4 mRNA CTD PMID:36139627 NCBI chr 6:27,786,619...27,796,710
Ensembl chr 6:27,786,619...27,796,710 		JBrowse link
G Pgbd5 piggyBac transposable element derived 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PGBD5 mRNA CTD PMID:36139627 NCBI chr19:52,336,751...52,401,906
Ensembl chr19:52,336,751...52,402,397 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PHLDA2 mRNA CTD PMID:36139627 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PHOSPHO1 mRNA CTD PMID:36139627 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342 		JBrowse link
G Phtf1 putative homeodomain transcription factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PHTF1 mRNA CTD PMID:36139627 NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078 		JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PHYHIP mRNA CTD PMID:36139627 NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221 		JBrowse link
G Piezo2 piezo-type mechanosensitive ion channel component 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PIEZO2 mRNA CTD PMID:36139627 NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PIK3IP1 mRNA CTD PMID:36139627 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PIK3R3 mRNA CTD PMID:36139627 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PIWIL2 mRNA CTD PMID:36139627 NCBI chr15:45,431,402...45,498,034
Ensembl chr15:45,431,703...45,497,702 		JBrowse link
G Pkd1l2 polycystin 1 like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PKD1L2 mRNA CTD PMID:36139627 NCBI chr19:45,049,713...45,136,503
Ensembl chr19:45,049,719...45,135,532 		JBrowse link
G Plac1 placenta enriched 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLAC1 mRNA CTD PMID:36139627 NCBI chr  X:132,821,347...132,955,143
Ensembl chr  X:132,821,347...132,985,668 		JBrowse link
G Plag1 PLAG1 zinc finger multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLAG1 mRNA CTD PMID:36139627 NCBI chr 5:16,902,057...16,956,727
Ensembl chr 5:16,905,394...16,913,647 		JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PLAT mRNA CTD PMID:36139627 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLAUR mRNA CTD PMID:36139627 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLCXD3 mRNA CTD PMID:36139627 NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384 		JBrowse link
G Pld1 phospholipase D1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PLD1 mRNA CTD PMID:36139627 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Plek2 pleckstrin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLEK2 mRNA CTD PMID:36139627 NCBI chr 6:97,700,123...97,719,417
Ensembl chr 6:97,701,106...97,719,326 		JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLIN1 mRNA CTD PMID:36139627 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Plin4 perilipin 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PLIN4 mRNA CTD PMID:36139627 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056 		JBrowse link
G Plxna2 plexin A2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PLXNA2 mRNA CTD PMID:36139627 NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979 		JBrowse link
G Podxl podocalyxin-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PODXL mRNA CTD PMID:36139627 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899 		JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POU2F2 mRNA CTD PMID:36139627 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261 		JBrowse link
G Pou2f3 POU class 2 homeobox 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POU2F3 mRNA CTD PMID:36139627 NCBI chr 8:43,495,408...43,577,795
Ensembl chr 8:43,495,527...43,577,795 		JBrowse link
G Pou6f1 POU class 6 homeobox 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of POU6F1 mRNA CTD PMID:36139627 NCBI chr 7:131,677,719...131,700,869
Ensembl chr 7:131,680,141...131,686,843
Ensembl chr 7:131,680,141...131,686,843 		JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PPFIA3 mRNA CTD PMID:36139627 NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798 		JBrowse link
G Ppm1n protein phosphatase, Mg2+/Mn2+ dependent 1N multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PPM1N mRNA CTD PMID:36139627 NCBI chr 1:78,929,350...78,934,435
Ensembl chr 1:78,929,351...78,932,685 		JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PPP1R16B mRNA CTD PMID:36139627 NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937 		JBrowse link
G Prag1 PEAK1 related kinase activating pseudokinase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRAG1 mRNA CTD PMID:36139627 NCBI chr16:56,087,885...56,141,153
Ensembl chr16:56,087,885...56,141,153 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PREX1 mRNA CTD PMID:36139627 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRICKLE1 mRNA CTD PMID:36139627 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRKG2 mRNA CTD PMID:36139627 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
G Prnd prion like protein doppel multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRND mRNA CTD PMID:36139627 NCBI chr 3:119,213,462...119,218,742
Ensembl chr 3:119,213,429...119,218,745 		JBrowse link
G Prodh proline dehydrogenase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PRODH mRNA CTD PMID:36139627 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Prodh2 proline dehydrogenase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRODH2 mRNA CTD PMID:36139627 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162 		JBrowse link
G Prr5l proline rich 5 like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRR5L mRNA CTD PMID:36139627 NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763 		JBrowse link
G Prss22 serine protease 22 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRSS22 mRNA CTD PMID:36139627 NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863 		JBrowse link
G Prss53 serine protease 53 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRSS53 mRNA CTD PMID:36139627 NCBI chr 1:182,494,944...182,501,607
Ensembl chr 1:182,494,955...182,500,115 		JBrowse link
G Prtn3 proteinase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PRTN3 mRNA CTD PMID:36139627 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PSD3 mRNA CTD PMID:36139627 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547 		JBrowse link
G Psmb10 proteasome 20S subunit beta 10 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PSMB10 mRNA CTD PMID:36139627 NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PSMB9 mRNA CTD PMID:36139627 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Ptgir prostaglandin I2 receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PTGIR mRNA CTD PMID:36139627 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979 		JBrowse link
G Ptk6 protein tyrosine kinase 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PTK6 mRNA CTD PMID:36139627 NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664 		JBrowse link
G Pxmp2 peroxisomal membrane protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PXMP2 mRNA CTD PMID:36139627 NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557 		JBrowse link
G Pygb glycogen phosphorylase B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PYGB mRNA CTD PMID:36139627 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553 		JBrowse link
G Rab11fip4 RAB11 family interacting protein 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB11FIP4 mRNA CTD PMID:36139627 NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759 		JBrowse link
G Rab38 RAB38, member RAS oncogene family multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB38 mRNA CTD PMID:36139627 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB39A mRNA CTD PMID:36139627 NCBI chr 8:54,088,246...54,105,867
Ensembl chr 8:54,088,129...54,106,483 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAB7B mRNA CTD PMID:36139627 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAC2 mRNA CTD PMID:36139627 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RAPGEF5 mRNA CTD PMID:36139627 NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936 		JBrowse link
G Rasa4 RAS p21 protein activator 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RASA4B mRNA CTD PMID:36139627 NCBI chr12:20,552,805...20,580,177
Ensembl chr12:20,552,806...20,580,147 		JBrowse link
G Rasl11a RAS-like family 11 member A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RASL11A mRNA CTD PMID:36139627 NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576 		JBrowse link
G Rassf9 Ras association domain family member 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RASSF9 mRNA CTD PMID:36139627 NCBI chr 7:37,599,720...37,631,553
Ensembl chr 7:37,599,720...37,635,245 		JBrowse link
G Reep1 receptor accessory protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of REEP1 mRNA CTD PMID:36139627 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338 		JBrowse link
G Rem2 RRAD and GEM like GTPase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of REM2 mRNA CTD PMID:36139627 NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429 		JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RGMB mRNA CTD PMID:36139627 NCBI chr 1:56,766,598...56,792,396
Ensembl chr 1:56,767,850...56,792,425 		JBrowse link
G Ribc2 RIB43A domain with coiled-coils 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RIBC2 mRNA CTD PMID:36139627 NCBI chr 7:116,242,863...116,257,868
Ensembl chr 7:116,242,863...116,257,863 		JBrowse link
G Rimkla ribosomal modification protein rimK-like family member A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RIMKLA mRNA CTD PMID:36139627 NCBI chr 5:133,072,179...133,098,840
Ensembl chr 5:133,073,960...133,098,792 		JBrowse link
G Rnf182 ring finger protein 182 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RNF182 mRNA CTD PMID:36139627 NCBI chr17:21,026,110...21,081,760
Ensembl chr17:21,030,214...21,094,911 		JBrowse link
G Rnf223 ring finger protein 223 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RNF223 mRNA CTD PMID:36139627 NCBI chr 5:166,723,346...166,726,236
Ensembl chr 5:166,724,984...166,725,751 		JBrowse link
G Robo4 roundabout guidance receptor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ROBO4 mRNA CTD PMID:36139627 NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ROR2 mRNA CTD PMID:36139627 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Rora RAR-related orphan receptor A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RORA mRNA CTD PMID:36139627 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO sotorasib results in decreased phosphorylation of RPS6 protein CTD PMID:31666701 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rragd Ras-related GTP binding D multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RRAGD mRNA CTD PMID:36139627 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356 		JBrowse link
G Rspo1 R-spondin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RSPO1 mRNA CTD PMID:36139627 NCBI chr 5:137,251,629...137,273,273
Ensembl chr 5:137,251,659...137,272,933 		JBrowse link
G RT1-Ha RT1 class II, locus Ha multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of HLA-DPA1 mRNA CTD PMID:36139627 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
G Rtn2 reticulon 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RTN2 mRNA CTD PMID:36139627 NCBI chr 1:78,935,056...78,948,069
Ensembl chr 1:78,935,104...78,948,069 		JBrowse link
G Rtp4 receptor (chemosensory) transporter protein 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of RTP4 mRNA CTD PMID:36139627 NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RUNX2 mRNA CTD PMID:36139627 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rxfp4 relaxin family peptide/INSL5 receptor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RXFP4 mRNA CTD PMID:36139627 NCBI chr 2:174,123,510...174,124,664 JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RYR1 mRNA CTD PMID:36139627 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G S100a2 S100 calcium binding protein A2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of S100A2 mRNA CTD PMID:36139627 NCBI chr 2:176,077,081...176,078,325 JBrowse link
G Sall4 spalt-like transcription factor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SALL4 mRNA CTD PMID:36139627 NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822 		JBrowse link
G Samd15 sterile alpha motif domain containing 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SAMD15 mRNA CTD PMID:36139627 NCBI chr 6:106,841,405...106,856,197
Ensembl chr 6:106,840,781...106,860,423 		JBrowse link
G Samd9l sterile alpha motif domain containing 9 like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SAMD9L mRNA CTD PMID:36139627 NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415 		JBrowse link
G Saxo5 stabilizer of axonemal microtubules 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SAXO5 mRNA CTD PMID:36139627 NCBI chr12:1,520,983...1,538,127
Ensembl chr12:1,521,014...1,538,118 		JBrowse link
G Scarf1 scavenger receptor class F, member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SCARF1 mRNA CTD PMID:36139627 NCBI chr10:60,359,213...60,371,516
Ensembl chr10:60,359,197...60,371,516 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SCNN1B mRNA CTD PMID:36139627 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Sdcbp2 syndecan binding protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SDCBP2 mRNA CTD PMID:36139627 NCBI chr 3:140,060,746...140,098,063
Ensembl chr 3:140,070,540...140,098,057 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SEC14L2 mRNA CTD PMID:36139627 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Sema3c semaphorin 3C multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SEMA3C mRNA CTD PMID:36139627 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SEMA7A mRNA CTD PMID:36139627 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Serpina3n serpin family A member 3N multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINA3 mRNA CTD PMID:36139627 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpina5 serpin family A member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINA5 mRNA CTD PMID:36139627 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Serpinb8 serpin family B member 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINB8 mRNA CTD PMID:36139627 NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINE1 mRNA CTD PMID:36139627 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpine2 serpin family E member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINE2 mRNA CTD PMID:36139627 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Serpini1 serpin family I member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SERPINI1 mRNA CTD PMID:36139627 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135 		JBrowse link
G Sfn stratifin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SFN mRNA CTD PMID:36139627 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SFXN2 mRNA CTD PMID:36139627 NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411 		JBrowse link
G Sfxn3 sideroflexin 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SFXN3 mRNA CTD PMID:36139627 NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073 		JBrowse link
G Sh2d5 SH2 domain containing 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SH2D5 mRNA CTD PMID:36139627 NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955 		JBrowse link
G Sh3d21 SH3 domain containing 21 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SH3D21 mRNA CTD PMID:36139627 NCBI chr 5:138,429,180...138,444,540
Ensembl chr 5:138,429,180...138,444,407 		JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SH3TC2 mRNA CTD PMID:36139627 NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083 		JBrowse link
G Shf Src homology 2 domain containing F multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SHF mRNA CTD PMID:36139627 NCBI chr 3:109,296,517...109,316,315
Ensembl chr 3:109,296,784...109,316,328 		JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SIGLEC15 mRNA CTD PMID:36139627 NCBI chr18:71,506,416...71,521,894
Ensembl chr18:71,505,399...71,521,881 		JBrowse link
G Slc10a5 solute carrier family 10, member 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC10A5 mRNA CTD PMID:36139627 NCBI chr 2:91,457,540...91,458,844
Ensembl chr 2:91,444,454...91,489,651 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC17A7 mRNA CTD PMID:36139627 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC2A3 mRNA CTD PMID:36139627 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC47A2 mRNA CTD PMID:36139627 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Slc4a11 solute carrier family 4 member 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC4A11 mRNA CTD PMID:36139627 NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC4A7 mRNA CTD PMID:36139627 NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC5A1 mRNA CTD PMID:36139627 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLC6A9 mRNA CTD PMID:36139627 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Slc9a3 solute carrier family 9 member A3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SLC9A3 mRNA CTD PMID:36139627 NCBI chr 1:29,124,633...29,167,912
Ensembl chr 1:29,124,674...29,167,417 		JBrowse link
G Slitrk3 SLIT and NTRK-like family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SLITRK3 mRNA CTD PMID:36139627 NCBI chr 2:157,680,067...157,697,404
Ensembl chr 2:157,687,535...157,696,709 		JBrowse link
G Smim5 small integral membrane protein 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SMIM5 mRNA CTD PMID:36139627 NCBI chr10:101,134,033...101,139,814
Ensembl chr10:101,134,033...101,139,813 		JBrowse link
G Smoc2 SPARC related modular calcium binding 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SMOC2 mRNA CTD PMID:36139627 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SMPD3 mRNA CTD PMID:36139627 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SNAI2 mRNA CTD PMID:36139627 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Snai3 snail family transcriptional repressor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SNAI3 mRNA CTD PMID:36139627 NCBI chr19:50,516,771...50,529,295
Ensembl chr19:50,516,771...50,523,486 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SOCS2 mRNA CTD PMID:36139627 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Spata18 spermatogenesis associated 18 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SPATA18 mRNA CTD PMID:36139627 NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687 		JBrowse link
G Spats2l spermatogenesis associated, serine-rich 2-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPATS2L mRNA CTD PMID:36139627 NCBI chr 9:59,319,949...59,493,864
Ensembl chr 9:59,320,276...59,493,967 		JBrowse link
G Spns3 SPNS lysolipid transporter 3, sphingosine-1-phosphate multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPNS3 mRNA CTD PMID:36139627 NCBI chr10:57,114,247...57,169,056
Ensembl chr10:57,114,266...57,168,951 		JBrowse link
G Spocd1 SPOC domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPOCD1 mRNA CTD PMID:36139627 NCBI chr 5:142,288,822...142,297,113 JBrowse link
G Spon1 spondin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPON1 mRNA CTD PMID:36139627 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SPSB1 mRNA CTD PMID:36139627 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468 		JBrowse link
G Sptb spectrin, beta, erythrocytic multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPTB mRNA CTD PMID:36139627 NCBI chr 6:95,310,342...95,437,221
Ensembl chr 6:95,310,326...95,437,118 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SPTBN4 mRNA CTD PMID:36139627 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228 		JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SRXN1 mRNA CTD PMID:36139627 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ST3GAL1 mRNA CTD PMID:36139627 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G Stambpl1 STAM binding protein-like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STAMBPL1 mRNA CTD PMID:36139627 NCBI chr 1:231,699,620...231,745,034
Ensembl chr 1:231,699,995...231,745,032 		JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STC1 mRNA CTD PMID:36139627 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Stn1 STN1 subunit of CST complex multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STN1 mRNA CTD PMID:36139627 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Stom stomatin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of STOM mRNA CTD PMID:36139627 NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354 		JBrowse link
G Sulf2 sulfatase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SULF2 mRNA CTD PMID:36139627 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SULT2B1 mRNA CTD PMID:36139627 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295 		JBrowse link
G Sycp2 synaptonemal complex protein 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYCP2 mRNA CTD PMID:36139627 NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789 		JBrowse link
G Sync syncoilin, intermediate filament protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SYNC mRNA CTD PMID:36139627 NCBI chr 5:141,631,837...141,656,184
Ensembl chr 5:141,632,367...141,688,659 		JBrowse link
G Syne3 spectrin repeat containing, nuclear envelope family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYNE3 mRNA CTD PMID:36139627 NCBI chr 6:123,872,895...123,964,773
Ensembl chr 6:123,873,174...123,953,409 		JBrowse link
G Syt12 synaptotagmin 12 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYT12 mRNA CTD PMID:36139627 NCBI chr 1:201,729,307...201,760,192
Ensembl chr 1:201,730,371...201,759,609 		JBrowse link
G Syt5 synaptotagmin 5 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYT5 mRNA CTD PMID:36139627 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Sytl2 synaptotagmin-like 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SYTL2 mRNA CTD PMID:36139627 NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222 		JBrowse link
G Tac3 tachykinin precursor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TAC3 mRNA CTD PMID:36139627 NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170 		JBrowse link
G Tafa2 TAFA chemokine like family member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TAFA2 mRNA CTD PMID:36139627 NCBI chr 7:58,942,598...59,418,640
Ensembl chr 7:58,942,610...59,417,299 		JBrowse link
G Tapbpl TAP binding protein-like multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TAPBPL mRNA CTD PMID:36139627 NCBI chr 4:158,021,454...158,028,905 JBrowse link
G Tbx4 T-box transcription factor 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TBX4 mRNA CTD PMID:36139627 NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825 		JBrowse link
G Tcaf2 TRPM8 channel-associated factor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TCAF2 mRNA CTD PMID:36139627
G Tchh trichohyalin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TCHH mRNA CTD PMID:36139627 NCBI chr 2:179,103,660...179,112,014
Ensembl chr 2:179,109,609...179,110,985
Ensembl chr 2:179,109,609...179,110,985 		JBrowse link
G Tex9 testis expressed 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TEX9 mRNA CTD PMID:36139627 NCBI chr 8:73,168,519...73,213,935
Ensembl chr 8:73,177,810...73,214,261 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TFPI2 mRNA CTD PMID:36139627 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Tfr2 transferrin receptor 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TFR2 mRNA CTD PMID:36139627 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
G Tjp3 tight junction protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TJP3 mRNA CTD PMID:36139627 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279 		JBrowse link
G Tlcd1 TLC domain containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TLCD1 mRNA CTD PMID:36139627 NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501 		JBrowse link
G Tle6 TLE family member 6, subcortical maternal complex member multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TLE6 mRNA CTD PMID:36139627 NCBI chr 7:8,107,050...8,118,639
Ensembl chr 7:8,107,207...8,118,639 		JBrowse link
G Tlr1 toll-like receptor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TLR1 mRNA CTD PMID:36139627 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TLR3 mRNA CTD PMID:36139627 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr6 toll-like receptor 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TLR6 mRNA CTD PMID:36139627 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tm4sf19 transmembrane 4 L six family member 19 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TM4SF19 mRNA CTD PMID:36139627 NCBI chr11:68,372,945...68,386,192
Ensembl chr11:68,371,647...68,384,591 		JBrowse link
G Tmc8 transmembrane channel-like 8 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMC8 mRNA CTD PMID:36139627 NCBI chr10:103,000,038...103,010,601
Ensembl chr10:102,998,402...103,010,590 		JBrowse link
G Tmem117 transmembrane protein 117 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM117 mRNA CTD PMID:36139627 NCBI chr 7:125,757,591...126,219,692
Ensembl chr 7:125,757,591...126,219,690 		JBrowse link
G Tmem144 transmembrane protein 144 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM144 mRNA CTD PMID:36139627 NCBI chr 2:164,960,649...164,993,562
Ensembl chr 2:164,961,247...164,992,368 		JBrowse link
G Tmem156 transmembrane protein 156 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM156 mRNA CTD PMID:36139627 NCBI chr14:43,221,464...43,252,453
Ensembl chr14:43,223,381...43,252,449 		JBrowse link
G Tmem158 transmembrane protein 158 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM158 mRNA CTD PMID:36139627 NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673 		JBrowse link
G Tmem236 transmembrane protein 236 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM236 mRNA CTD PMID:36139627 NCBI chr17:77,180,919...77,241,258
Ensembl chr17:77,188,163...77,238,671 		JBrowse link
G Tmem25 transmembrane protein 25 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM25 mRNA CTD PMID:36139627 NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389 		JBrowse link
G Tmem255b transmembrane protein 255B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM255B mRNA CTD PMID:36139627 NCBI chr16:76,079,840...76,108,179
Ensembl chr16:76,079,845...76,106,795 		JBrowse link
G Tmem269 transmembrane protein 269 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM269 mRNA CTD PMID:36139627 NCBI chr 5:132,817,324...132,836,360
Ensembl chr 5:132,817,324...132,829,977 		JBrowse link
G Tmem270 transmembrane protein 270 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM270 mRNA CTD PMID:36139627 NCBI chr12:21,793,631...21,798,723
Ensembl chr12:21,794,130...21,798,731 		JBrowse link
G Tmem45a transmembrane protein 45A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM45A mRNA CTD PMID:36139627 NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526 		JBrowse link
G Tmem92 transmembrane protein 92 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TMEM92 mRNA CTD PMID:36139627 NCBI chr10:79,749,242...79,760,807 JBrowse link
G Tnfsf15 TNF superfamily member 15 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TNFSF15 mRNA CTD PMID:36139627 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tnxb tenascin XB multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TNXB mRNA CTD PMID:36139627
G Tp53i3 tumor protein p53 inducible protein 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TP53I3 mRNA CTD PMID:36139627 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TPH1 mRNA CTD PMID:36139627 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TRANK1 mRNA CTD PMID:36139627 NCBI chr 8:111,275,973...111,355,491
Ensembl chr 8:111,276,354...111,355,092 		JBrowse link
G Trib1 tribbles pseudokinase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIB1 mRNA CTD PMID:36139627 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIB2 mRNA CTD PMID:36139627 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Trim29 tripartite motif-containing 29 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TRIM29 mRNA CTD PMID:36139627 NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992 		JBrowse link
G Trim63 tripartite motif containing 63 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIM63 mRNA CTD PMID:36139627 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
G Trim9 tripartite motif-containing 9 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRIM9 mRNA CTD PMID:36139627 NCBI chr 6:88,756,824...88,856,588
Ensembl chr 6:88,757,303...88,856,542 		JBrowse link
G Trmt9b tRNA methyltransferase 9B (putative) multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TRMT9B mRNA CTD PMID:36139627 NCBI chr16:55,740,551...55,792,198
Ensembl chr16:55,743,018...55,792,144 		JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TRPV2 mRNA CTD PMID:36139627 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TSC22D3 mRNA CTD PMID:36139627 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tsnaxip1 translin-associated factor X interacting protein 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TSNAXIP1 mRNA CTD PMID:36139627 NCBI chr19:33,716,834...33,734,824
Ensembl chr19:33,716,785...33,734,824 		JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TTC39A mRNA CTD PMID:36139627 NCBI chr 5:124,165,102...124,204,740
Ensembl chr 5:124,151,760...124,204,973 		JBrowse link
G Ttpa alpha tocopherol transfer protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TTPA mRNA CTD PMID:36139627 NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073 		JBrowse link
G Tuba1a tubulin, alpha 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TUBA1A mRNA CTD PMID:36139627 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Txk TXK tyrosine kinase multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of TXK mRNA CTD PMID:36139627 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448 		JBrowse link
G Uap1l1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of UAP1L1 mRNA CTD PMID:36139627 NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443 		JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of UBA7 mRNA CTD PMID:36139627 NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099 		JBrowse link
G Ufsp1 UFM1-specific peptidase 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of UFSP1 mRNA CTD PMID:36139627 NCBI chr12:19,406,133...19,407,147
Ensembl chr12:19,406,142...19,407,195 		JBrowse link
G Uhrf2 ubiquitin like with PHD and ring finger domains 2 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of UHRF2 mRNA CTD PMID:36139627 NCBI chr 1:227,814,639...227,877,907
Ensembl chr 1:227,814,963...227,877,904 		JBrowse link
G Upk1a uroplakin 1A multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of UPK1A mRNA CTD PMID:36139627 NCBI chr 1:85,859,672...85,870,147
Ensembl chr 1:85,859,671...85,870,354 		JBrowse link
G Upk3b uroplakin 3B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of UPK3B mRNA CTD PMID:36139627 NCBI chr12:20,630,231...20,637,634
Ensembl chr12:20,631,525...20,637,724 		JBrowse link
G Ush1g USH1 protein network component sans multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of USH1G mRNA CTD PMID:36139627 NCBI chr10:100,559,721...100,563,590
Ensembl chr10:100,557,629...100,563,590 		JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of VDR mRNA CTD PMID:36139627 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of VEPH1 mRNA CTD PMID:36139627 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266 		JBrowse link
G Vgf VGF nerve growth factor inducible multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of VGF mRNA CTD PMID:36139627 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Vtn vitronectin multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of VTN mRNA CTD PMID:36139627 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810 		JBrowse link
G Wasf3 WASP family member 3 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WASF3 mRNA CTD PMID:36139627 NCBI chr12:8,563,805...8,660,799
Ensembl chr12:8,562,062...8,660,751 		JBrowse link
G Wnt10b Wnt family member 10B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT10B mRNA CTD PMID:36139627 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt11 Wnt family member 11 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT11 mRNA CTD PMID:36139627 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt2b Wnt family member 2B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT2B mRNA CTD PMID:36139627 NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308 		JBrowse link
G Wnt4 Wnt family member 4 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of WNT4 mRNA CTD PMID:36139627 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wnt7b Wnt family member 7B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of WNT7B mRNA CTD PMID:36139627 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
G Wnt8b Wnt family member 8B multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of WNT8B mRNA CTD PMID:36139627 NCBI chr 1:243,354,145...243,376,000
Ensembl chr 1:243,354,086...243,374,286 		JBrowse link
G Xaf1 XIAP associated factor 1 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of XAF1 mRNA CTD PMID:36139627 NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770 		JBrowse link
G Zc3h6 zinc finger CCCH type containing 6 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ZC3H6 mRNA CTD PMID:36139627 NCBI chr 3:116,203,466...116,254,186
Ensembl chr 3:116,204,197...116,253,282 		JBrowse link
G Zfp608 zinc finger protein 608 multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ZNF608 mRNA CTD PMID:36139627 NCBI chr18:48,304,873...48,412,846
Ensembl chr18:48,304,880...48,410,465 		JBrowse link
G Zwint ZW10 interacting kinetochore protein multiple interactions ISO [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ZWINT mRNA CTD PMID:36139627 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
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  CHEBI ontology 19874
    role 19844
      application 19689
        pharmaceutical 19525
          drug 19525
            antineoplastic agent 17817
              sotorasib 606
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  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      carboacyl group 17694
                                        univalent carboacyl group 17694
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              alpha,beta-unsaturated carboxylic acid amide 7109
                                                enamide 7109
                                                  acrylamides 6347
                                                    sotorasib 606
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