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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-methylumbelliferyl acetate
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Accession:CHEBI:17763 term browser browse the term
Definition:An acetate ester consiting of umbelliferone carrying a 7-O-acetyl group.
Synonyms:exact_synonym: 4-methyl-2-oxo-2H-chromen-7-yl acetate
 related_synonym: 4-methyl-7-acetyloxy coumarin;   7-(Acetyloxy)-4-methyl-2-benzopyrone;   7-(acetyloxy)-4-methyl-2H-1-benzopyran-2-one;   7-Acetoxy-4-methylcoumarin;   7-acetoxy-4-methylchromen-2-one;   Formula=C12H10O4;   InChI=1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3;   InChIKey=HXVZGASCDAGAPS-UHFFFAOYSA-N;   SMILES=CC(=O)Oc1ccc2c(C)cc(=O)oc2c1;   beta-Methylumbelliferyl acetate
 alt_id: CHEBI:110551;   CHEBI:12031;   CHEBI:1906;   CHEBI:20453
 xref: CAS:2747-05-9;   HMDB:HMDB0032989;   KEGG:C03837
 xref_mesh: MESH:C032078
 xref: MetaCyc:CPD-181;   PMID:11888210;   PMID:23245880;   Patent:US2008009544;   Patent:WO2007107846;   Reaxys:189667


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4-methylumbelliferyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calr calreticulin increases activity ISO 4-methylumbelliferyl acetate results in increased activity of CALR protein CTD PMID:20188080 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis		 ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; tropacocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis ISO CES2 protein results in increased hydrolysis of 4-methylumbelliferyl acetate CTD PMID:9169443 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Txn1 thioredoxin 1 increases activity ISO 4-methylumbelliferyl acetate results in increased activity of TXN protein CTD PMID:24103856 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO 4-methylumbelliferyl acetate results in increased expression of VEGFA protein CTD PMID:24103856 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        probe 515
          fluorescent probe 442
            umbelliferone 111
              4-methylumbelliferyl acetate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  oxacycle 17906
                                    benzopyran 11972
                                      1-benzopyran 11726
                                        chromenes 4433
                                          chromenone 4378
                                            coumarins 4143
                                              hydroxycoumarin 356
                                                umbelliferone 111
                                                  4-methylumbelliferyl acetate 5
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