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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-dimethylformamide
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Accession:CHEBI:17741 term browser browse the term
Definition:A member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups.
Synonyms:related_synonym: DMF;   Dimethylformamide;   Formula=C3H7NO;   InChI=1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3;   InChIKey=ZMXDDKWLCZADIW-UHFFFAOYSA-N;   N,N-Dimethylmethanamide;   N-Formyldimethylamine;   SMILES=[H]C(=O)N(C)C
 alt_id: CHEBI:12425;   CHEBI:21454;   CHEBI:42077;   CHEBI:7076
 xref: CAS:68-12-2;   DrugBank:DB01844;   HMDB:HMDB0001888;   KEGG:C03134
 xref_mesh: MESH:D004126
 xref: MetaCyc:CPD-581;   PDBeChem:DMF;   PMID:18666198;   PMID:19608215;   PMID:23313473;   PMID:3824392;   Reaxys:605365;   Wikipedia:Dimethylformamide


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N,N-dimethylformamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression EXP Dimethylformamide results in decreased expression of ABCB1B mRNA CTD PMID:12883083 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of ADGRE1 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of ADGRE1 protein] 		CTD PMID:37995826 NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,242,474...2,398,000 		JBrowse link
G Arg1 arginase 1 decreases expression ISO Dimethylformamide results in decreased expression of ARG1 mRNA CTD PMID:37995826 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		ISO Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of BAX protein] CTD PMID:29984871 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression 		EXP
ISO 		[Dimethylformamide co-treated with Carbon Tetrachloride] results in decreased expression of BCL2L1 protein
Thiocarbamates analog inhibits the reaction [Dimethylformamide results in decreased expression of BCL2L1 protein]
Dimethylformamide results in increased expression of BCL2L1 protein 		CTD PMID:20097184 PMID:29984871 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of and results in increased cleavage of CASP1 protein]; Dimethylformamide results in increased expression of and results in increased cleavage of CASP1 protein CTD PMID:37995826 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression 		EXP
ISO 		[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased activity of CASP3 protein
CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP3 protein modified form]; Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of CASP3 protein modified form] 		CTD PMID:20097184 PMID:29984871 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression 		ISO CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP9 protein modified form]; Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of CASP9 protein modified form] CTD PMID:29984871 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP3 protein modified form]; CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP9 protein modified form]; CAT protein inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein] CTD PMID:29984871 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of CCL2 mRNA] CTD PMID:37995826 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cd163 CD163 molecule decreases expression ISO Dimethylformamide results in decreased expression of CD163 mRNA CTD PMID:37995826 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation
multiple interactions 		ISO Dimethylformamide results in increased phosphorylation of CHUK protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased phosphorylation of CHUK protein] 		CTD PMID:37995826 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing
increases oxidation
increases metabolic processing
increases expression
multiple interactions
increases abundance
increases response to substance 		ISO
EXP 		CYP2E1 protein polymorphism affects the metabolism of Dimethylformamide
CYP2E1 protein results in increased oxidation of Dimethylformamide
CYP2E1 protein affects the metabolism of Dimethylformamide
CYP2E1 protein results in increased metabolism of Dimethylformamide
Dimethylformamide results in increased expression of CYP2E1 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in decreased activity of CYP2E1 protein]; CYP2E1 protein affects the reaction [Dimethylformamide results in increased activity of GPT protein]; CYP2E1 protein affects the reaction [Dimethylformamide results in increased expression of HSP90B1 protein]; Dimethylformamide results in decreased expression of and results in decreased activity of CYP2E1 protein
CYP2E1 polymorphism results in increased abundance of Dimethylformamide metabolite
CYP2E1 protein results in increased susceptibility to Dimethylformamide 		CTD PMID:9817075 PMID:10207612 PMID:11305777 PMID:15772367 PMID:29984871 More... NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of DDIT3 mRNA CTD PMID:20097184 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of EIF2AK3 protein modified form CTD PMID:20097184 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of GCLC protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of GCLC protein] 		CTD PMID:37995826 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases activity
multiple interactions 		ISO Dimethylformamide results in increased activity of GOT1 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased activity of GOT1 protein] 		CTD PMID:37995826 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased activity of GPT protein]; CYP2E1 protein affects the reaction [Dimethylformamide results in increased activity of GPT protein] CTD PMID:31501917 PMID:37995826 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsr glutathione-disulfide reductase decreases expression EXP Dimethylformamide results in decreased expression of GSR mRNA CTD PMID:12883083 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Dimethylformamide results in increased expression of H2AX protein CTD PMID:26387567 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression 		ISO Alitretinoin inhibits the reaction [Dimethylformamide results in decreased expression of HMOX1 protein]; U 0126 inhibits the reaction [Dimethylformamide results in decreased expression of HMOX1 protein]
Dimethylformamide results in decreased expression of HMOX1 mRNA; Dimethylformamide results in decreased expression of HMOX1 protein
Dimethylformamide results in increased expression of HMOX1 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of HMOX1 protein] 		CTD PMID:31875996 PMID:37995826 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
increases expression 		EXP
ISO 		[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSP90B1 protein
CYP2E1 protein affects the reaction [Dimethylformamide results in increased expression of HSP90B1 protein] 		CTD PMID:20097184 PMID:31501917 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSPA5 mRNA; [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSPA5 protein CTD PMID:20097184 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of IL1B mRNA
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of and results in increased cleavage of IL1B protein]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of and results in increased secretion of IL1B protein]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of IL1B mRNA]; Dimethylformamide results in increased expression of and results in increased cleavage of IL1B protein; Dimethylformamide results in increased expression of and results in increased secretion of IL1B protein 		CTD PMID:37995826 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of and results in increased secretion of IL6 protein]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of IL6 mRNA]; Dimethylformamide results in increased expression of and results in increased secretion of IL6 protein CTD PMID:37995826 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases activity 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased activity of LDHA protein] CTD PMID:37995826 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Ltf lactotransferrin increases expression ISO Dimethylformamide results in increased expression of LTF mRNA CTD PMID:18063697 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO U 0126 inhibits the reaction [Dimethylformamide results in increased phosphorylation of MAPK1 protein]
[Dimethylformamide results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of RXRA protein; Dimethylformamide results in increased phosphorylation of MAPK1 protein 		CTD PMID:31875996 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions 		ISO [Dimethylformamide results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of RXRA protein; Dimethylformamide results in increased phosphorylation of MAPK3 protein
U 0126 inhibits the reaction [Dimethylformamide results in increased phosphorylation of MAPK3 protein] 		CTD PMID:31875996 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mpo myeloperoxidase increases expression ISO Dimethylformamide results in increased expression of MPO mRNA CTD PMID:18063697 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression ISO Dimethylformamide results in decreased expression of MRC1 mRNA CTD PMID:37995826 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Mrc2 mannose receptor, C type 2 decreases expression ISO Dimethylformamide results in decreased expression of MRC2 mRNA CTD PMID:37995826 NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease increases expression ISO Dimethylformamide results in increased expression of MRE11 mRNA; Dimethylformamide results in increased expression of MRE11 protein CTD PMID:26387567 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression ISO Dimethylformamide results in increased expression of NCF1 mRNA CTD PMID:18063697 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Dimethylformamide affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:84,044,428...84,054,413
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases activity
increases expression 		ISO Alitretinoin inhibits the reaction [Dimethylformamide results in decreased activity of NFE2L2 protein]; Dimethylformamide promotes the reaction [NFE2L2 protein binds to RXRA protein]; U 0126 inhibits the reaction [Dimethylformamide results in decreased activity of NFE2L2 protein]
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of NFE2L2 protein] 		CTD PMID:31875996 PMID:37995826 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased phosphorylation of NFKBIA protein] CTD PMID:37995826 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of NLRP3 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of NLRP3 protein] 		CTD PMID:37995826 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of NOS2 mRNA]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of NOS2 protein]
Dimethylformamide results in increased expression of NOS2 mRNA; Dimethylformamide results in increased expression of NOS2 protein 		CTD PMID:37995826 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases expression
increases expression 		ISO Alitretinoin inhibits the reaction [Dimethylformamide results in decreased expression of NQO1 protein]; U 0126 inhibits the reaction [Dimethylformamide results in decreased expression of NQO1 protein]
Dimethylformamide results in decreased expression of NQO1 mRNA; Dimethylformamide results in decreased expression of NQO1 protein
Dimethylformamide results in increased expression of NQO1 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of NQO1 protein] 		CTD PMID:31875996 PMID:37995826 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased cleavage of PARP1 protein CTD PMID:20097184 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of PTGS2 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of PTGS2 protein] 		CTD PMID:37995826 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pycard PYD and CARD domain containing increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of PYCARD protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of PYCARD protein] 		CTD PMID:37995826 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO Dimethylformamide results in increased expression of RAD50 mRNA; Dimethylformamide results in increased expression of RAD50 protein CTD PMID:26387567 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rad51 RAD51 recombinase increases expression ISO Dimethylformamide results in increased expression of RAD51 mRNA; Dimethylformamide results in increased expression of RAD51 protein CTD PMID:26387567 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of and results in increased phosphorylation of RELA protein]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased phosphorylation of RELA protein]; Dimethylformamide results in increased expression of and results in increased phosphorylation of RELA protein CTD PMID:37995826 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rxra retinoid X receptor alpha decreases degradation
increases phosphorylation
multiple interactions 		ISO Dimethylformamide results in decreased degradation of RXRA protein
[Dimethylformamide results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of RXRA protein; [Dimethylformamide results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of RXRA protein
Alitretinoin inhibits the reaction [Dimethylformamide results in decreased degradation of RXRA protein]; Dimethylformamide promotes the reaction [NFE2L2 protein binds to RXRA protein]; U 0126 inhibits the reaction [Dimethylformamide results in decreased degradation of RXRA protein] 		CTD PMID:31875996 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions 		ISO Dimethylformamide results in increased expression of SOD1 mRNA; Dimethylformamide results in increased expression of SOD1 protein
allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of SOD1 protein] 		CTD PMID:35238128 PMID:37995826 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:14570759 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO Dimethylformamide inhibits the reaction [SULT2A1 protein results in increased sulfation of 1-hydroxypyrene] CTD PMID:14570759 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
increases expression 		ISO allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of and results in increased secretion of TNF protein]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased expression of TNF mRNA]; allyl methyl disulfide inhibits the reaction [Dimethylformamide results in increased secretion of TNF protein]; Dimethylformamide results in increased expression of and results in increased secretion of TNF protein CTD PMID:37995826 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO Dimethylformamide results in increased expression of TNFSF10 mRNA; Dimethylformamide results in increased expression of TNFSF10 protein CTD PMID:18063697 NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		ISO CAT protein inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein]; Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein]
Dimethylformamide results in increased expression of TP53 protein modified form 		CTD PMID:29984871 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression ISO Dimethylformamide results in decreased expression of TRIM28 mRNA CTD PMID:35238128 NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 increases expression
affects expression 		ISO Dimethylformamide results in increased expression of XRCC2 protein
Dimethylformamide affects the expression of XRCC2 mRNA 		CTD PMID:26387567 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO Dimethylformamide results in increased expression of XRCC3 mRNA; Dimethylformamide results in increased expression of XRCC3 protein CTD PMID:26387567 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 increases expression ISO Dimethylformamide results in increased expression of ZP2 mRNA CTD PMID:35238128 NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      application 20617
        solvent 17470
          formamide 154
            N,N-dimethylformamide 57
              N,N-dimethylformamide dimethyl acetal 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            heteroorganic entity 20215
                              organochalcogen compound 19902
                                organooxygen compound 19804
                                  carbon oxoacid 19150
                                    carboxylic acid 19147
                                      carboacyl group 18082
                                        univalent carboacyl group 18082
                                          carbamoyl group 17918
                                            carboxamide 17918
                                              formamides 1819
                                                formamide 154
                                                  N,N-dimethylformamide 57
                                                    N,N-dimethylformamide dimethyl acetal 0
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