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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3-bisphospho-D-glyceric acid
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Accession:CHEBI:17720 term browser browse the term
Definition:The D-enantiomer of 2,3-bisphosphoglyceric acid.
Synonyms:related_synonym: (2R)-2,3-bis(phosphonooxy)-Propanoic acid;   2,3-BPG;   2,3-Bisphospho-D-glycerate;   2,3-Bisphosphoglyceric acid;   2,3-Disphospho-D-glycerate;   2,3-diphosphoglyceric acid;   D-Greenwald ester;   DPG;   Formula=C3H8O10P2;   Glyceric acid bis(dihydrogen phosphate);   Glyceric acid diphosphate;   InChI=1S/C3H8O10P2/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11)/t2-/m1/s1;   InChIKey=XOHUEYCVLUUEJJ-UWTATZPHSA-N;   SMILES=OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O
 alt_id: CHEBI:11417;   CHEBI:19306;   CHEBI:872
 xref: CAS:138-81-8;   HMDB:HMDB0001294;   KEGG:C01159
 xref_mesh: MESH:D019794
 xref: MetaCyc:23-DIPHOSPHOGLYCERATE;   PDBeChem:DG2;   PMID:1257232;   PMID:15882454;   PMID:2111310;   PMID:3702645;   PMID:625775;   PMID:685194;   PMID:7308813;   PMID:7376803;   PMID:8735521;   PMID:9708696;   Reaxys:1729440
 cyclic_relationship: is_conjugate_acid_of CHEBI:58248



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2,3-bisphospho-D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          metabolite 19562
            fundamental metabolite 14526
              glyceric acid 7
                2,3-bisphosphoglyceric acid 4
                  2,3-bisphospho-D-glyceric acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      chalcogen 19598
                        oxygen atom 19570
                          oxygen molecular entity 19570
                            hydroxides 19374
                              oxoacid 18808
                                pnictogen oxoacid 14987
                                  phosphorus oxoacid 14587
                                    phosphoric acids 13935
                                      phosphoric acid 13935
                                        phosphoric acid derivative 13817
                                          phosphate 13843
                                            organic phosphate 13816
                                              carbohydrate phosphate 1964
                                                aldonic acid phosphate 7
                                                  phosphoglyceric acid 7
                                                    bisphosphoglyceric acid 4
                                                      2,3-bisphosphoglyceric acid 4
                                                        2,3-bisphospho-D-glyceric acid 4
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