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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:FIN56
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Accession:CHEBI:176419 term browser browse the term
Definition:A fluorene that is N-9H-fluoren-9-ylidenehydroxylamine substituted by N-cyclohexylsulfonyl groups at positions 2 and 7. It induces ferroptosis via degradation of GPX4 and also binds and activates squalene synthase.
Synonyms:exact_synonym: N,N'-dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
 related_synonym: FIN 56;   Formula=C25H31N3O5S2;   InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2;   InChIKey=JLCFMMIWBSZOIS-UHFFFAOYSA-N;   N(2),N(7)-dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide;   SMILES=ON=C1C2=C(C=CC(=C2)S(=O)(=O)NC2CCCCC2)C2=C1C=C(C=C2)S(=O)(=O)NC1CCCCC1
 xref: CAS:1083162-61-1;   PMID:27159577;   PMID:27315536;   PMID:29610484;   PMID:30057310;   PMID:30686534;   PMID:30863316;   PMID:31441366;   PMID:33414455


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Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        biochemical role 19574
          ferroptosis inducer 15760
            FIN56 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    main group molecular entity 19835
                      s-block molecular entity 19669
                        hydrogen molecular entity 19651
                          hydrides 19162
                            organic hydride 18712
                              organic fundamental parent 18712
                                hydrocarbon 18460
                                  cyclic hydrocarbon 17248
                                    arene 17229
                                      polycyclic arene 17053
                                        ortho-fused polycyclic arene 9850
                                          fluorene 559
                                            fluorenes 431
                                              9-hydroxyiminofluorene-2,7-disulfonamide 0
                                                FIN56 0
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