Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:D-glucose
go back to main search page
Accession:CHEBI:17634 term browser browse the term
Definition:A glucose with D-configuration.
Synonyms:exact_synonym: D-gluco-hexose
 related_synonym: Formula=C6H12O6;   Traubenzucker;   dextrose;   grape sugar
 alt_id: CHEBI:12965;   CHEBI:20999
 xref: CAS:50-99-7
 xref_mesh: MESH:D005947


show annotations for term's descendants           Sort by:
D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions		 EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]		 CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G GH1 growth hormone 1 multiple interactions EXP GH1 protein inhibits the reaction [Lipopolysaccharides results in decreased abundance of Glucose] CTD PMID:9185964 NCBI chr12:15,064,965...15,066,698
Ensembl chr12:15,064,909...15,066,696 		JBrowse link
G INS insulin multiple interactions
increases transport		 EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502 PMID:8699633 PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LOC102165256 V-type proton ATPase subunit G 1 pseudogene decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 7:19,272,032...19,272,926 JBrowse link
G MLXIP MLX interacting protein increases expression
multiple interactions		 EXP Glucose results in increased expression of MLXIP mRNA
Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]		 CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP Glucose results in increased expression of NOS2 protein
Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein]		 CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression		 EXP T0901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA] CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP Glucose results in increased expression of PTGS2 protein
Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein]		 CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
2-deoxy-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] CTD PMID:25087994 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein; Quercetin promotes the reaction [[Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein] CTD PMID:25087994 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G NOS3 nitric oxide synthase 3 decreases expression EXP Deoxyglucose results in decreased expression of NOS3 mRNA CTD PMID:11382920 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
aldehydo-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions		 EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]		 CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G GH1 growth hormone 1 multiple interactions EXP GH1 protein inhibits the reaction [Lipopolysaccharides results in decreased abundance of Glucose] CTD PMID:9185964 NCBI chr12:15,064,965...15,066,698
Ensembl chr12:15,064,909...15,066,696 		JBrowse link
G INS insulin multiple interactions
increases transport		 EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502 PMID:8699633 PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LOC102165256 V-type proton ATPase subunit G 1 pseudogene decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 7:19,272,032...19,272,926 JBrowse link
G MLXIP MLX interacting protein increases expression
multiple interactions		 EXP Glucose results in increased expression of MLXIP mRNA
Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]		 CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression		 EXP T0901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA] CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein] CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
mogroside V term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of IL18 mRNA] CTD PMID:35134483 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression EXP mogroside V results in increased expression of IL1B mRNA CTD PMID:35134483
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein] CTD PMID:35134483 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of NOS2 mRNA] CTD PMID:35134483 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA] CTD PMID:35134483 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein] CTD PMID:35134483 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA] CTD PMID:35134483 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
neomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A1 solute carrier family 5 member 1 decreases expression EXP Neomycin results in decreased expression of SLC5A1 mRNA; Neomycin results in decreased expression of SLC5A1 protein CTD PMID:12927799 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841 		JBrowse link
notoginsenoside R1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 decreases expression EXP notoginsenoside R1 results in decreased expression of IL10 protein CTD PMID:25721049 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL4 interleukin 4 decreases expression EXP notoginsenoside R1 results in decreased expression of IL4 protein CTD PMID:25721049 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5151
    role 5118
      biological role 5118
        biochemical role 5042
          metabolite 5030
            fundamental metabolite 157
              glucose 21
                D-glucose 21
                  2-deoxy-2-fluoro-D-glucose + 0
                  2-deoxy-D-glucose + 3
                  2-deoxy-D-glucose 6-phosphate 0
                  2-deoxy-D-glucose 6-phosphate(2-) 0
                  3,6-anhydro-D-glucose 0
                  6-O-acetyl-D-glucose + 0
                  D-glucofuranose + 0
                  D-glucopyranose + 13
                  D-glucopyranose 1-phosphate + 0
                  D-glucose 1,6-bisphosphate + 0
                  D-glucose 6-phosphate + 0
                  D-glucose 6-sulfate 0
                  D-glucose monophosphate + 0
                  D-glucose-(13)C6 0
                  aldehydo-D-glucose + 10
                  alpha-D-glucose-1,2-((13)C2) 0
                  royal jelly 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5151
    subatomic particle 5142
      composite particle 5142
        hadron 5142
          baryon 5142
            nucleon 5142
              atomic nucleus 5142
                atom 5142
                  main group element atom 5115
                    p-block element atom 5112
                      carbon group element atom 5030
                        carbon atom 5029
                          organic molecular entity 5029
                            heteroorganic entity 4874
                              organochalcogen compound 4828
                                organooxygen compound 4792
                                  carbohydrates and carbohydrate derivatives 123
                                    carbohydrate 123
                                      monosaccharide 48
                                        aldose 25
                                          aldohexose 21
                                            glucose 21
                                              D-glucose 21
                                                2-deoxy-2-fluoro-D-glucose + 0
                                                2-deoxy-D-glucose + 3
                                                2-deoxy-D-glucose 6-phosphate 0
                                                2-deoxy-D-glucose 6-phosphate(2-) 0
                                                3,6-anhydro-D-glucose 0
                                                6-O-acetyl-D-glucose + 0
                                                D-glucofuranose + 0
                                                D-glucopyranose + 13
                                                D-glucopyranose 1-phosphate + 0
                                                D-glucose 1,6-bisphosphate + 0
                                                D-glucose 6-phosphate + 0
                                                D-glucose 6-sulfate 0
                                                D-glucose monophosphate + 0
                                                D-glucose-(13)C6 0
                                                aldehydo-D-glucose + 10
                                                alpha-D-glucose-1,2-((13)C2) 0
                                                royal jelly 0
paths to the root