hydroquinone - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	hydroquinone	go back to main search page
Accession:	CHEBI:17594	browse the term
Definition:	A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Synonyms:	related_synonym:	1,4-Benzenediol; 1,4-Dihydroxybenzene; 4-Hydroxyphenol; Benzene-1,4-diol; Eldoquin; Formula=C6H6O2; InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H; InChIKey=QIGBRXMKCJKVMJ-UHFFFAOYSA-N; Quinol; SMILES=Oc1ccc(O)cc1; p-Benzenediol; p-Hydroquinone; p-hydroxyphenol
	alt_id:	CHEBI:14416; CHEBI:24645; CHEBI:5793
	xref:	Beilstein:605970; CAS:123-31-9; Drug_Central:3282; Gmelin:2742; HMDB:HMDB0002434; KEGG:C00530; KEGG:C15603; KEGG:D00073; KNApSAcK:C00002656
	xref_mesh:	MESH:C031927
	xref:	MetaCyc:HYDROQUINONE; PMID:11170505; PMID:12213471; PMID:1395635; PMID:15618234; PMID:15894107; PMID:1899343; PMID:19148301; PMID:24407054; PMID:24858384; PMID:25586344; PPDB:1503; Reaxys:605970; UM-BBD_compID:c0091; Wikipedia:Hydroquinone

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Genes (1007)

hydroquinone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha 1,4-galactosyltransferase

decreases expression

hydroquinone results in decreased expression of A4GALT mRNA

NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071

G

apoptosis antagonizing transcription factor

multiple interactions
increases expression
increases ADP-ribosylation

PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein]
hydroquinone results in increased ADP-ribosylation of AATF protein

NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201

G

ATP binding cassette subfamily C member 3

increases expression

hydroquinone results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

angiotensin converting enzyme 2

decreases expression

hydroquinone results in decreased expression of ACE2 mRNA

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

ADAM metallopeptidase domain 17

increases expression
multiple interactions

hydroquinone results in increased expression of ADAM17 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; ADAM17 protein affects the reaction [hydroquinone results in increased secretion of TNF protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

G

ArfGAP with dual PH domains 2

increases expression

hydroquinone results in increased expression of ADAP2 mRNA

NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604

G

adenosine deaminase RNA specific B2

multiple interactions

hydroquinone inhibits the reaction [Estradiol results in increased expression of ADARB2 mRNA]

NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831

G

ADP-ribosylarginine hydrolase

increases expression

hydroquinone results in increased expression of ADPRH mRNA

NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931

G

androgen-dependent TFPI-regulating protein

increases expression

hydroquinone results in increased expression of ADTRP mRNA

NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826

G

apoptosis enhancing nuclease

increases expression

hydroquinone results in increased expression of AEN mRNA

NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523

G

actin filament associated protein 1

decreases expression

hydroquinone results in decreased expression of AFAP1 mRNA

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

angiogenic factor with G patch and FHA domains 1

decreases expression

hydroquinone results in decreased expression of AGGF1 mRNA

NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952

G

aryl hydrocarbon receptor

affects localization
multiple interactions
increases expression

hydroquinone affects the localization of AHR protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; hydroquinone results in increased expression of and affects the localization of AHR protein
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]

PMID:15935814 PMID:29935983 PMID:35123993

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

AIF family member 2

increases expression

hydroquinone results in increased expression of AIFM2 mRNA

NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236

G

aldo-keto reductase family 1 member B10

decreases expression

hydroquinone results in decreased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

AKT serine/threonine kinase 1

multiple interactions
decreases phosphorylation

hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of AKT1 protein]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein]
4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]

PMID:17464197 PMID:28883758 PMID:37148176

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 2

multiple interactions

hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein]

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

G

AKT serine/threonine kinase 3

multiple interactions

hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein]

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

G

albumin

multiple interactions

ALB protein binds to and affects the transport of hydroquinone

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member L2

increases expression

hydroquinone results in increased expression of ALDH1L2 mRNA

NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 2 family member

increases expression

hydroquinone results in increased expression of ALDH2 mRNA

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A1

increases expression

hydroquinone results in increased expression of ALDH3A1 mRNA

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

arachidonate 12-lipoxygenase, 12S type

increases expression

hydroquinone results in increased expression of ALOX12 mRNA

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

G

arachidonate 12-lipoxygenase, 12R type

increases expression

hydroquinone results in increased expression of ALOX12B mRNA

NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938

G

arachidonate epidermal lipoxygenase 3

increases expression

hydroquinone results in increased expression of ALOXE3 mRNA

NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328

G

alpha-kinase 1

increases expression

hydroquinone results in increased expression of ALPK1 mRNA

NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157

G

alpha-1-microglobulin/bikunin precursor

increases expression

hydroquinone results in increased expression of AMBP mRNA

NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331

G

ankyrin repeat and death domain containing 1A

decreases expression

hydroquinone results in decreased expression of ANKDD1A mRNA

NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651

G

annexin A1

increases expression

hydroquinone results in increased expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A3

increases expression

hydroquinone results in increased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

apolipoprotein E

decreases expression
multiple interactions

hydroquinone results in decreased expression of APOE mRNA
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA]

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

multiple interactions

[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 3 (Gill blood group)

decreases expression

hydroquinone results in decreased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

arginase 1

increases expression

hydroquinone results in increased expression of ARG1 mRNA

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

arginase 2

increases expression

hydroquinone results in increased expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 27

increases expression

hydroquinone results in increased expression of ARHGAP27 mRNA

NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185

G

Rho GTPase activating protein 42

decreases expression

hydroquinone results in decreased expression of ARHGAP42 mRNA

NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870

G

Rho GDP dissociation inhibitor alpha

affects expression

hydroquinone affects the expression of ARHGDIA protein

NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023

G

Rho/Rac guanine nucleotide exchange factor 2

increases expression

hydroquinone results in increased expression of ARHGEF2 mRNA

NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355

G

Rho guanine nucleotide exchange factor 26

decreases expression

hydroquinone results in decreased expression of ARHGEF26 mRNA

NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819

G

ADP ribosylation factor like GTPase 3

decreases expression

hydroquinone results in decreased expression of ARL3 mRNA

NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820

G

aryl hydrocarbon receptor nuclear translocator

increases expression
multiple interactions

hydroquinone results in increased expression of ARNT protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ARNT protein]

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

hydroquinone results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

aspartic peptidase, retroviral-like 1

increases expression

hydroquinone results in increased expression of ASPRV1 mRNA

NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379

G

activating transcription factor 2

increases phosphorylation
multiple interactions

hydroquinone results in increased phosphorylation of ATF2 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]; ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]

PMID:23288922 PMID:23791922

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

activating transcription factor 3

increases expression

hydroquinone results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

increases expression

hydroquinone results in increased expression of ATF4 mRNA; hydroquinone results in increased expression of ATF4 protein

PMID:15452088 PMID:24053669

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

multiple interactions
decreases expression
increases expression

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; [Sirolimus co-treated with hydroquinone] results in decreased expression of ATF6 protein; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]
hydroquinone results in decreased expression of ATF6 mRNA; hydroquinone results in decreased expression of ATF6 protein

PMID:36646296 PMID:37148176

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 12

increases expression

hydroquinone results in increased expression of ATG12 protein

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 5

multiple interactions
increases expression

PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA]

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

autophagy related 7

increases expression

hydroquinone results in increased expression of ATG7 protein

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

G

ATPase secretory pathway Ca2+ transporting 2

increases expression

hydroquinone results in increased expression of ATP2C2 mRNA

NCBI chr19:47,754,120...47,811,369
Ensembl chr19:47,754,120...47,811,368

G

ATPase H+ transporting V1 subunit C2

increases expression

hydroquinone results in increased expression of ATP6V1C2 mRNA

NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028

G

alpha-2-glycoprotein 1, zinc-binding

increases expression

hydroquinone results in increased expression of AZGP1 mRNA

NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091

G

BTB domain and CNC homolog 1

multiple interactions
decreases expression
affects localization

[ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
hydroquinone results in decreased expression of BACH1 protein
hydroquinone affects the localization of BACH1 protein

PMID:23290930 PMID:28645578

NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447

G

BCL2-associated agonist of cell death

decreases expression

hydroquinone results in decreased expression of BAD mRNA

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BAG cochaperone 1

decreases expression

hydroquinone results in decreased expression of BAG1 mRNA

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

G

BMP and activin membrane-bound inhibitor

increases expression

hydroquinone results in increased expression of BAMBI mRNA

NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060

G

BCL2 associated X, apoptosis regulator

decreases expression
increases expression
multiple interactions

hydroquinone results in decreased expression of BAX protein
hydroquinone results in increased expression of BAX protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of BAX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; Sirolimus promotes the reaction [hydroquinone results in increased expression of BAX protein]

PMID:27515134 PMID:27606422 PMID:28843007 PMID:33771647 PMID:33932074 More...

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

increases expression

hydroquinone results in increased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCL11 transcription factor A

decreases expression

hydroquinone results in decreased expression of BCL11A mRNA

NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180

G

BCL11 transcription factor B

decreases expression

hydroquinone results in decreased expression of BCL11B mRNA

NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224

G

BCL2, apoptosis regulator

multiple interactions
decreases expression
increases expression

[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein]
hydroquinone results in decreased expression of BCL2 mRNA; hydroquinone results in decreased expression of BCL2 protein
hydroquinone promotes the reaction [XBP1 protein affects the expression of BCL2 mRNA]; XBP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 mRNA]
hydroquinone results in increased expression of BCL2 mRNA; hydroquinone results in increased expression of BCL2 protein

PMID:23288922 PMID:24053669 PMID:27515134 PMID:27606422 PMID:28444915 More...

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression
increases expression

hydroquinone results in decreased expression of BCL2L1 protein
hydroquinone results in increased expression of BCL2L1 protein

PMID:23288922 PMID:35561756

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

3-hydroxybutyrate dehydrogenase 2

decreases expression

hydroquinone results in decreased expression of BDH2 mRNA

NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072

G

beclin 1

increases expression
multiple interactions

hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein
PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]

PMID:28263894 PMID:35302183 PMID:37148176

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

BH3 interacting domain death agonist

increases cleavage
multiple interactions

hydroquinone results in increased cleavage of BID protein
FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

baculoviral IAP repeat-containing 3

increases expression
decreases expression

hydroquinone results in increased expression of BIRC3 mRNA
hydroquinone results in decreased expression of BIRC3 mRNA

PMID:15452088 PMID:31256213

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

decreases expression
multiple interactions

hydroquinone results in decreased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

BCL2 interacting protein 3

decreases expression

hydroquinone results in decreased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

bora, aurora kinase A activator

decreases expression

hydroquinone results in decreased expression of BORA mRNA

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

G

BPI fold containing family C

increases expression

hydroquinone results in increased expression of BPIFC mRNA

NCBI chr 7:17,848,787...17,905,993
Ensembl chr 7:17,861,007...17,905,919

G

BRCA1, DNA repair associated

increases expression

hydroquinone results in increased expression of BRCA1 protein

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

bone marrow stromal cell antigen 2

decreases expression

hydroquinone results in decreased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

BTG anti-proliferation factor 2

increases expression

hydroquinone results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

beta-transducin repeat containing E3 ubiquitin protein ligase

multiple interactions

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein]; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; Chloroquine inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA]; Dactinomycin promotes the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA]

NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721

G

BUB3 mitotic checkpoint protein

decreases expression

hydroquinone results in decreased expression of BUB3 mRNA

NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036

G

similar to human chromosome 16 open reading frame 74

increases expression

hydroquinone results in increased expression of C16ORF74 mRNA

NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349

G

similar to human chromosome 15 open reading frame 48

increases expression

hydroquinone results in increased expression of C15ORF48 mRNA

NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006

G

calbindin 2

increases expression

hydroquinone results in increased expression of CALB2 mRNA

NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438

G

calcitonin-related polypeptide, beta

increases expression

hydroquinone results in increased expression of CALCB mRNA

NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125

G

calcium homeostasis modulator family member 6

decreases expression

hydroquinone results in decreased expression of CALHM6 mRNA

NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278

G

calmodulin-like 3

decreases expression

hydroquinone results in decreased expression of CALML3 mRNA

NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175

G

calpain 2

decreases activity

hydroquinone results in decreased activity of CAPN2 protein

NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969

G

carbonic anhydrase 3

decreases expression

hydroquinone results in decreased expression of CA3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 9

decreases expression

hydroquinone results in decreased expression of CA9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

caspase 1

increases cleavage
multiple interactions

hydroquinone results in increased cleavage of CASP1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 12

multiple interactions

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of CASP12 protein]

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

multiple interactions
increases activity
increases degradation
increases cleavage
increases expression
decreases activity
decreases expression

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; hydroquinone results in decreased expression of and results in increased cleavage of CASP3 protein; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]
hydroquinone results in decreased activity of CASP3 protein
[hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein
hydroquinone results in decreased expression of CASP3 mRNA; hydroquinone results in decreased expression of CASP3 protein

PMID:15337166 PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

increases cleavage

hydroquinone results in increased cleavage of CASP4 protein

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 6

decreases expression

hydroquinone results in decreased expression of CASP6 mRNA

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 7

increases cleavage
increases expression
decreases activity
multiple interactions

hydroquinone results in increased cleavage of CASP7 protein
hydroquinone results in increased expression of CASP7 protein modified form
hydroquinone results in decreased activity of CASP7 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]

PMID:19064679 PMID:22960397 PMID:28886972

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

multiple interactions
increases cleavage
increases expression
increases activity

FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP8 protein]
hydroquinone results in increased expression of CASP8 protein
hydroquinone results in increased activity of CASP8 protein

PMID:15777082 PMID:23288922 PMID:23776099 PMID:27606422

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

decreases expression
increases activity
increases expression
multiple interactions
increases cleavage

hydroquinone results in decreased expression of CASP9 mRNA; hydroquinone results in decreased expression of CASP9 protein
hydroquinone results in increased activity of CASP9 protein
hydroquinone results in increased expression of CASP9 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP9 protein]

PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 More...

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

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catalase

decreases response to substance
decreases activity

CAT protein results in decreased susceptibility to hydroquinone
hydroquinone results in decreased activity of CAT protein

PMID:10193577 PMID:26056850

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolae associated protein 2

decreases expression

hydroquinone results in decreased expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

G

cystathionine beta synthase

increases expression

hydroquinone results in increased expression of CBS mRNA

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

G

coiled-coil domain containing 127

decreases expression

hydroquinone results in decreased expression of CCDC127 mRNA

NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893

G

coiled-coil domain containing 163

decreases expression

hydroquinone results in decreased expression of CCDC163 mRNA

NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929

G

coiled-coil domain containing 8

decreases expression

hydroquinone results in decreased expression of CCDC8 mRNA

NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090

G

coiled-coil domain containing 88C

decreases expression

hydroquinone results in decreased expression of CCDC88C mRNA

NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555

G

C-C motif chemokine ligand 11

increases expression

hydroquinone results in increased expression of CCL11 protein

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 2

decreases secretion
decreases expression
multiple interactions
increases secretion
increases expression

hydroquinone results in decreased secretion of CCL2 protein
hydroquinone results in decreased expression of CCL2 mRNA
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein]
hydroquinone results in increased secretion of CCL2 protein
hydroquinone results in increased expression of CCL2 protein

PMID:17572062 PMID:20946948 PMID:22302391 PMID:22465845

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

increases expression

hydroquinone results in increased expression of CCL3 protein

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 4

increases expression

hydroquinone results in increased expression of CCL4 protein

PMID:17572062 PMID:18353026

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 5

increases expression

hydroquinone results in increased expression of CCL5 protein

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cellular communication network factor 1

affects expression

hydroquinone affects the expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

increases expression

hydroquinone results in increased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin A1

increases expression

hydroquinone results in increased expression of CCNA1 mRNA

NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157

G

cyclin D1

multiple interactions
increases expression
decreases expression

Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCND1 protein]
hydroquinone results in increased expression of CCND1 mRNA; hydroquinone results in increased expression of CCND1 protein

PMID:28886972 PMID:33932074 PMID:37951342

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin E1

increases expression
multiple interactions

hydroquinone results in increased expression of CCNE1 protein
MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCNE1 protein]

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

increases expression

hydroquinone results in increased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

cyclin F

decreases expression

hydroquinone results in decreased expression of CCNF mRNA

NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101

G

centriole, cilia and spindle-associated protein

decreases expression

hydroquinone results in decreased expression of CCSAP mRNA

NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753

G

Cd69 molecule

multiple interactions

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein]

NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542

G

Cd80 molecule

multiple interactions

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein]

NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030

G

CD86 molecule

increases expression
multiple interactions

hydroquinone results in increased expression of CD86 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]

PMID:19148301 PMID:19665512

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

cell division cycle associated 2

decreases expression

hydroquinone results in decreased expression of CDCA2 mRNA

NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611

G

cell division cycle associated 7

decreases expression

hydroquinone results in decreased expression of CDCA7 mRNA

NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353

G

cadherin 26

decreases expression

hydroquinone results in decreased expression of CDH26 mRNA

NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149

G

cyclin dependent kinase 2

multiple interactions
increases expression

MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK2 protein]

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

multiple interactions
increases expression

MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK4 protein]

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

hydroquinone results in increased expression of CDKN1A mRNA; hydroquinone results in increased expression of CDKN1A protein
SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein]

PMID:23416264 PMID:27515134

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

decreases expression

hydroquinone results in decreased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

multiple interactions
decreases expression

CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of TP53 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]
hydroquinone results in decreased expression of CDKN2A mRNA; hydroquinone results in decreased expression of CDKN2A protein

PMID:33771647 PMID:33932074

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

corneodesmosin

increases expression

hydroquinone results in increased expression of CDSN mRNA

NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250

G

cell migration inducing hyaluronidase 1

increases expression

hydroquinone results in increased expression of CEMIP mRNA

NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415

G

centromere protein A

decreases expression

hydroquinone results in decreased expression of CENPA mRNA

NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675

G

centrosomal protein 15

decreases expression

hydroquinone results in decreased expression of CEP15 mRNA

NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838

G

carboxylesterase 1D

increases expression

hydroquinone results in increased expression of CES1 mRNA

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

cilia and flagella associated protein 44

decreases expression

hydroquinone results in decreased expression of CFAP44 mRNA

NCBI chr11:56,199,772...56,283,964
Ensembl chr11:56,201,049...56,283,986

G

CASP8 and FADD-like apoptosis regulator

increases expression

hydroquinone results in increased expression of CFLAR mRNA

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

G

cholesterol 25-hydroxylase

increases expression

hydroquinone results in increased expression of CH25H mRNA

NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression
decreases expression

hydroquinone results in increased expression of CHAC1 mRNA
hydroquinone results in decreased expression of CHAC1 mRNA

PMID:29221148 PMID:31256213

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

calcineurin-like EF hand protein 2

decreases expression

hydroquinone results in decreased expression of CHP2 mRNA

NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139

G

carbohydrate sulfotransferase 2

increases expression

hydroquinone results in increased expression of CHST2 mRNA

NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955

G

component of inhibitor of nuclear factor kappa B kinase complex

multiple interactions

hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein]

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

chloride channel accessory 4

decreases expression

hydroquinone results in decreased expression of CLCA4 mRNA

NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089

G

claudin 8

decreases expression

hydroquinone results in decreased expression of CLDN8 mRNA

NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513

G

chloride intracellular channel 3

increases expression

hydroquinone results in increased expression of CLIC3 mRNA

NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018

G

CXADR-like membrane protein

increases expression

hydroquinone results in increased expression of CLMP mRNA

NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838

G

cytidine/uridine monophosphate kinase 2

decreases expression

hydroquinone results in decreased expression of CMPK2 mRNA

NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183

G

cornifelin

increases expression

hydroquinone results in increased expression of CNFN mRNA

NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747

G

chondromodulin

increases response to substance
increases expression
multiple interactions

CNMD protein results in increased susceptibility to hydroquinone
hydroquinone results in increased expression of CNMD mRNA
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]

NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297

G

collagen type I alpha 1 chain

increases expression
multiple interactions

hydroquinone results in increased expression of COL1A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type II alpha 1 chain

multiple interactions

[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein

PMID:29908986 PMID:29935983

NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546

G

collagen type IV alpha 1 chain

decreases expression
increases expression
multiple interactions

hydroquinone results in decreased expression of COL4A1 mRNA
hydroquinone results in increased expression of COL4A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type V alpha 2 chain

decreases expression

hydroquinone results in decreased expression of COL5A2 mRNA

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

cysteine-rich C-terminal 1

increases expression

hydroquinone results in increased expression of CRCT1 mRNA

NCBI chr 2:178,633,789...178,635,274
Ensembl chr 2:178,634,092...178,634,394

G

cAMP responsive element binding protein 1

multiple interactions
increases phosphorylation

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of CREB1 protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter]

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cysteine-rich secretory protein LCCL domain containing 2

increases expression

hydroquinone results in increased expression of CRISPLD2 mRNA

NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465

G

crystallin beta-gamma domain containing 2

increases expression

hydroquinone results in increased expression of CRYBG2 mRNA

NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666

G

colony stimulating factor 1 receptor

multiple interactions

hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 2

multiple interactions
decreases secretion

[CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein
hydroquinone results in decreased secretion of CSF2 protein
hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]

PMID:7884313 PMID:15129224 PMID:23559866

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

chondroitin sulfate N-acetylgalactosaminyltransferase 1

increases expression

hydroquinone results in increased expression of CSGALNACT1 mRNA

NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319

G

cysteine and serine rich nuclear protein 3

decreases expression

hydroquinone results in decreased expression of CSRNP3 mRNA

NCBI chr 3:50,498,379...50,695,598
Ensembl chr 3:50,498,633...50,685,950

G

cysteine and glycine-rich protein 2

decreases expression

hydroquinone results in decreased expression of CSRP2 mRNA

NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745

G

cystatin E/M

increases expression

hydroquinone results in increased expression of CST6 mRNA

NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030

G

cystathionine gamma-lyase

increases expression

hydroquinone results in increased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

catenin beta 1

multiple interactions
affects localization
decreases expression

hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]

PMID:28886972 PMID:30567741

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

C-X-C motif chemokine ligand 12

decreases expression
decreases secretion

hydroquinone results in decreased expression of CXCL12 mRNA
hydroquinone results in decreased secretion of CXCL12 protein

PMID:22960397 PMID:23559866

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

cytochrome c, somatic

affects localization
increases expression
multiple interactions

hydroquinone affects the localization of CYCS protein
hydroquinone results in increased expression of CYCS protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein]

PMID:15777082 PMID:15816534 PMID:35123993

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 1, subfamily a, polypeptide 1

affects response to substance
multiple interactions
increases expression

CYP1A1 protein affects the susceptibility to hydroquinone
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]
hydroquinone results in increased expression of CYP1A1 mRNA; hydroquinone results in increased expression of CYP1A1 protein

PMID:8242868 PMID:23416264 PMID:31256213 PMID:35123993

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

hydroquinone results in increased expression of CYP1B1 mRNA

PMID:23416264 PMID:31256213

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily b, polypeptide 1

multiple interactions

[CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 3

affects response to substance

CYP2B1 protein affects the susceptibility to hydroquinone

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily d, polypeptide 4

multiple interactions

[CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions
increases expression

[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]
hydroquinone results in increased expression of CYP2E1 mRNA
Resveratrol inhibits the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]
hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]

PMID:8211999 PMID:15051535 PMID:23202692 PMID:30567741

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

[CYP3A4 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

[CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 4, subfamily f, polypeptide 18

increases expression

hydroquinone results in increased expression of CYP4F18 mRNA; hydroquinone results in increased expression of CYP4F18 protein

NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940

G

cysteine rich tail 1

increases expression

hydroquinone results in increased expression of CYSRT1 mRNA

NCBI chr 3:8,054,195...8,057,846
Ensembl chr 3:8,053,482...8,059,721

G

death-associated protein

decreases expression

hydroquinone results in decreased expression of DAP mRNA

NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752

G

death associated protein-like 1

decreases expression

hydroquinone results in decreased expression of DAPL1 mRNA

NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

increases expression

hydroquinone results in increased expression of DAPP1 mRNA

NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423

G

dihydrolipoamide branched chain transacylase E2

decreases expression

hydroquinone results in decreased expression of DBT mRNA

NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609

G

defective in cullin neddylation 1 domain containing 3

increases expression

hydroquinone results in increased expression of DCUN1D3 mRNA

NCBI chr 1:174,243,001...174,285,647
Ensembl chr 1:66,494,848...66,496,343
Ensembl chr 1:66,494,848...66,496,343

G

dimethylarginine dimethylaminohydrolase 1

decreases expression

hydroquinone results in decreased expression of DDAH1 mRNA

NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

hydroquinone results in increased expression of DDIT3 mRNA; hydroquinone results in increased expression of DDIT3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; hydroquinone results in increased expression of and affects the localization of DDIT3 protein; ursodoxicoltaurine inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]
[XBP1 protein affects the susceptibility to hydroquinone] which affects the expression of DDIT3 protein; hydroquinone promotes the reaction [XBP1 protein affects the expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 protein]

PMID:23416264 PMID:24053669 PMID:31256213 PMID:32334435 PMID:36646296 More...

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression

hydroquinone results in increased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DEXD/H-box helicase 60

decreases expression

hydroquinone results in decreased expression of DDX60 mRNA

NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526

G

DEP domain containing 7

decreases expression

hydroquinone results in decreased expression of DEPDC7 mRNA

NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124

G

DEP domain containing MTOR-interacting protein

decreases expression

hydroquinone results in decreased expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

DNA fragmentation factor subunit beta

decreases expression

hydroquinone results in decreased expression of DFFB mRNA

NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628

G

dickkopf WNT signaling pathway inhibitor 1

affects expression

hydroquinone affects the expression of DKK1 mRNA

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression

hydroquinone results in increased expression of DNAJA1 mRNA

NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

hydroquinone results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

delta/notch-like EGF repeat containing

decreases expression

hydroquinone results in decreased expression of DNER mRNA

NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637

G

DNA methyltransferase 1

decreases expression
increases expression
affects expression

hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein
hydroquinone results in increased expression of DNMT1 mRNA
hydroquinone affects the expression of DNMT1 mRNA

PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 PMID:35135009

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

decreases expression
affects expression
increases expression

hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein
hydroquinone affects the expression of DNMT3A mRNA
hydroquinone results in increased expression of DNMT3A mRNA

PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

DNA methyltransferase 3 beta

decreases expression
multiple interactions
affects expression

hydroquinone results in decreased expression of DNMT3B mRNA
Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]

PMID:22245671 PMID:31899212 PMID:34612549

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

deltex E3 ubiquitin ligase 3L

decreases expression

hydroquinone results in decreased expression of DTX3L mRNA

NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538

G

dual specificity phosphatase 1

increases expression

hydroquinone results in increased expression of DUSP1 protein

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 19

decreases expression

hydroquinone results in decreased expression of DUSP19 mRNA

NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534

G

dual specificity phosphatase 5

increases expression

hydroquinone results in increased expression of DUSP5 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dual specificity phosphatase 6

increases expression

hydroquinone results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

DAZ interacting zinc finger protein 1

decreases expression

hydroquinone results in decreased expression of DZIP1 mRNA

NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066

G

E2F transcription factor 1

increases expression
multiple interactions

hydroquinone results in increased expression of E2F1 mRNA; hydroquinone results in increased expression of E2F1 protein
MIR7-2 promotes the reaction [hydroquinone results in increased expression of E2F1 protein]

PMID:33932074 PMID:37951342

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E4F transcription factor 1

increases expression
affects response to substance
multiple interactions

hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein
E4F1 protein affects the susceptibility to hydroquinone
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form

PMID:30448557 PMID:30506647

NCBI chr10:13,471,478...13,495,018
Ensembl chr10:13,474,456...13,485,974

G

extracellular matrix protein 2

increases expression

hydroquinone results in increased expression of ECM2 mRNA

NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516

G

endothelin 1

decreases expression

hydroquinone results in decreased expression of EDN1 mRNA

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

endothelin 2

decreases expression

hydroquinone results in decreased expression of EDN2 mRNA

NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814

G

eukaryotic elongation factor-2 kinase

decreases expression

hydroquinone results in decreased expression of EEF2K mRNA

NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164

G

ephrin A1

multiple interactions

[hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

early growth response 3

increases expression

hydroquinone results in increased expression of EGR3 mRNA

NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627

G

euchromatic histone lysine methyltransferase 2

decreases expression

hydroquinone results in decreased expression of EHMT2 protein

NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547

G

EP300 interacting inhibitor of differentiation 3

decreases expression

hydroquinone results in decreased expression of EID3 mRNA

NCBI chr 7:20,860,073...20,861,395

G

eukaryotic translation initiation factor 2 alpha kinase 3

increases phosphorylation
increases expression
multiple interactions

hydroquinone results in increased phosphorylation of EIF2AK3 protein
hydroquinone results in increased expression of EIF2AK3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]

PMID:24053669 PMID:36646296

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions
increases phosphorylation

XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased phosphorylation of EIF2S1 protein]

PMID:24053669 PMID:37148176

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

hydroquinone results in increased expression of EIF4EBP1 mRNA

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

ELAV like RNA binding protein 1

multiple interactions
increases degradation
decreases expression

ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]
hydroquinone results in increased degradation of ELAVL1 mRNA
hydroquinone results in decreased expression of ELAVL1 mRNA; hydroquinone results in decreased expression of ELAVL1 protein

NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784

G

ELAV like RNA binding protein 2

multiple interactions

[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]

NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097

G

E74 like ETS transcription factor 3

increases expression

hydroquinone results in increased expression of ELF3 mRNA

NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481

G

E74 like ETS transcription factor 5

increases expression

hydroquinone results in increased expression of ELF5 mRNA

NCBI chr 3:89,808,837...89,836,977
Ensembl chr 3:89,797,880...89,836,973

G

ELMO domain containing 1

increases expression

hydroquinone results in increased expression of ELMOD1 mRNA

NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140

G

ELOVL fatty acid elongase 4

increases expression

hydroquinone results in increased expression of ELOVL4 mRNA

NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697

G

ELOVL fatty acid elongase 5

decreases expression

hydroquinone results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

elongator acetyltransferase complex subunit 2

decreases expression

hydroquinone results in decreased expression of ELP2 mRNA

NCBI chr18:15,885,940...15,921,564
Ensembl chr18:15,885,934...15,921,599

G

erythrocyte membrane protein band 4.1-like 3

increases expression

hydroquinone results in increased expression of EPB41L3 mRNA

NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607

G

epoxide hydrolase 1

multiple interactions

EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

EPS8-like 1

increases expression

hydroquinone results in increased expression of EPS8L1 mRNA

NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524

G

erb-b2 receptor tyrosine kinase 2

decreases expression

hydroquinone results in decreased expression of ERBB2 mRNA

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

epiregulin

increases expression

hydroquinone results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

glutamate-rich 5

decreases expression

hydroquinone results in decreased expression of ERICH5 mRNA

NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions
increases expression

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ERN1 protein]

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

estrogen receptor 1

decreases expression

hydroquinone results in decreased expression of ESR1 mRNA

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

ETS variant transcription factor 4

increases expression

hydroquinone results in increased expression of ETV4 mRNA

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

exosome component 3

decreases expression

hydroquinone results in decreased expression of EXOSC3 mRNA

NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060

G

exosome component 6

increases expression

hydroquinone results in increased expression of EXOSC6 mRNA

NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

decreases expression

hydroquinone results in decreased expression of EZH2 protein

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

coagulation factor II (thrombin) receptor

decreases expression

hydroquinone results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

fatty acid binding protein 4

multiple interactions

[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

Fas associated via death domain

decreases expression
multiple interactions

hydroquinone results in decreased expression of FADD mRNA
FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]

PMID:15452088 PMID:23288922

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

G

family with sequence similarity 117, member B

decreases expression

hydroquinone results in decreased expression of FAM117B mRNA

NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483

G

family with sequence similarity 13, member A

decreases expression

hydroquinone results in decreased expression of FAM13A mRNA

NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860

G

family with sequence similarity 43, member A

increases expression

hydroquinone results in increased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

family with sequence similarity 83, member D

decreases expression

hydroquinone results in decreased expression of FAM83D mRNA

NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192

G

Fas cell surface death receptor

increases expression
multiple interactions

hydroquinone results in increased expression of FAS protein
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein

PMID:23776099 PMID:28444915

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

increases expression

hydroquinone results in increased expression of FASLG protein

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

FAU ubiquitin like and ribosomal protein S30 fusion

multiple interactions

FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein]

NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742

G

F-box protein 5

decreases expression

hydroquinone results in decreased expression of FBXO5 mRNA

NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437

G

fibroblast growth factor receptor 3

decreases expression

hydroquinone results in decreased expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

fin bud initiation factor homolog

increases expression

hydroquinone results in increased expression of FIBIN mRNA

NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676

G

filaggrin

increases expression

hydroquinone results in increased expression of FLG mRNA; hydroquinone results in increased expression of FLG protein

NCBI chr 2:178,884,793...178,912,986

G

filaggrin 2

increases expression

hydroquinone results in increased expression of FLG2 mRNA

NCBI chr 2:178,789,792...178,802,232

G

fibronectin 1

affects expression

hydroquinone affects the expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression
increases phosphorylation
multiple interactions

hydroquinone results in decreased expression of FOS mRNA
hydroquinone results in increased phosphorylation of FOS protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of FOS protein]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter]

PMID:15452088 PMID:23791922

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

increases expression

hydroquinone results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

FRY microtubule binding protein

increases expression

hydroquinone results in increased expression of FRY mRNA

NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116

G

fibrous sheath interacting protein 1

increases expression

hydroquinone results in increased expression of FSIP1 mRNA

NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167

G

ferritin heavy chain 1

increases expression

hydroquinone results in increased expression of FTH1 mRNA; hydroquinone results in increased expression of FTH1 protein

PMID:15452088 PMID:23738040

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

fucosyltransferase 1

decreases expression

hydroquinone results in decreased expression of FUT1 mRNA

NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616

G

frizzled class receptor 2

decreases expression

hydroquinone results in decreased expression of FZD2 mRNA

NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334

G

G0/G1switch 2

increases expression

hydroquinone results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

growth arrest and DNA-damage-inducible, alpha

increases expression

hydroquinone results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest-specific 1

decreases expression

hydroquinone results in decreased expression of GAS1 mRNA

NCBI chr17:4,482,168...4,485,153

G

golgi associated kinase 1B

decreases expression

hydroquinone results in decreased expression of GASK1B mRNA

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

GATA binding protein 1

decreases expression
multiple interactions

hydroquinone results in decreased expression of GATA1 mRNA
Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]

PMID:21414390 PMID:23973255 PMID:37329354

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

G

GATA binding protein 2

multiple interactions
decreases expression

hydroquinone affects the reaction [Hemin affects the expression of GATA2 mRNA]; hydroquinone inhibits the reaction [Hemin results in decreased expression of GATA2 protein]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBG2 gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBM gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene]; hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroquinone results in decreased expression of GATA2 mRNA

PMID:21414390 PMID:37329354

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

G

guanylate binding protein 2

decreases expression

hydroquinone results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

glutamate-cysteine ligase, catalytic subunit

increases expression
multiple interactions
affects methylation

hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein
[hydroquinone affects the methylation of GCLC promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of GCLC promoter] which results in increased abundance of 5-hydroxymethylcytosine; Resveratrol promotes the reaction [hydroquinone results in increased expression of GCLC mRNA]; TET1 protein affects the reaction [hydroquinone results in increased expression of GCLC mRNA]

PMID:23290930 PMID:23940045 PMID:30547568 PMID:32334435

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein

PMID:21059386 PMID:30547568 PMID:31256213

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

guanine deaminase

increases expression

hydroquinone results in increased expression of GDA mRNA

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

growth differentiation factor 15

increases expression

hydroquinone results in increased expression of GDF15 mRNA

PMID:23416264 PMID:31256213

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

glycerophosphodiester phosphodiesterase domain containing 3

increases expression

hydroquinone results in increased expression of GDPD3 mRNA

NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063

G

glutamine fructose-6-phosphate transaminase 1

increases expression

hydroquinone results in increased expression of GFPT1 mRNA

NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471

G

glycerol kinase

increases expression

hydroquinone results in increased expression of GK mRNA

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

glycosylated lysosomal membrane protein

decreases expression

hydroquinone results in decreased expression of GLMP mRNA

NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960

G

glutaredoxin

increases expression

hydroquinone results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutamate-ammonia ligase

decreases expression

hydroquinone results in decreased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

guanosine monophosphate reductase

decreases expression

hydroquinone results in decreased expression of GMPR mRNA

NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621

G

golgi SNAP receptor complex member 2

decreases expression

hydroquinone results in decreased expression of GOSR2 mRNA

NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625

G

glutamic-oxaloacetic transaminase 1

increases expression

hydroquinone results in increased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate acyltransferase 3

increases expression

hydroquinone results in increased expression of GPAT3 mRNA

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

G protein-coupled receptor 155

decreases expression

hydroquinone results in decreased expression of GPR155 mRNA

NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275

G

G protein-coupled receptor 15 ligand

decreases expression

hydroquinone results in decreased expression of GPR15LG mRNA

NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876

G

G protein-coupled receptor, class C, group 5, member A

decreases expression

hydroquinone results in decreased expression of GPRC5A mRNA

NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260

G

glutathione peroxidase 2

increases expression

hydroquinone results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

growth factor receptor bound protein 10

increases expression

hydroquinone results in increased expression of GRB10 mRNA

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

growth factor receptor bound protein 2

affects expression

hydroquinone affects the expression of GRB2 protein

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

G

grainyhead-like transcription factor 1

increases expression

hydroquinone results in increased expression of GRHL1 mRNA

NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301

G

gasdermin D

increases expression
multiple interactions

hydroquinone results in increased expression of GSDMD protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]

NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055

G

glycogen synthase kinase 3 beta

multiple interactions

hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein]

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione-disulfide reductase

multiple interactions

hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein]

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

increases expression
multiple interactions

hydroquinone results in increased expression of GSS protein
NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase mu 1

affects response to substance

GSTM1 affects the susceptibility to hydroquinone; GSTM1 gene polymorphism affects the susceptibility to hydroquinone

PMID:15141365 PMID:19778234

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase pi 1

affects response to substance

GSTP1 affects the susceptibility to hydroquinone

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 1

increases expression
affects response to substance

hydroquinone results in increased expression of GSTT1 mRNA
GSTT1 affects the susceptibility to hydroquinone

PMID:19778234 PMID:23290930

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

GTP binding protein 2

increases expression

hydroquinone results in increased expression of GTPBP2 mRNA

NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241

G

guanylate cyclase 1 soluble subunit beta 1

increases expression

hydroquinone results in increased expression of GUCY1B1 mRNA

NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916

G

GTPase, very large interferon inducible 1

decreases expression

hydroquinone results in decreased expression of GVINP1 mRNA

NCBI chr 1:160,279,767...160,306,701
Ensembl chr 1:160,277,126...160,306,331

G

glycophorin A

decreases expression

hydroquinone results in decreased expression of GYPA protein

NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822

G

H1.4 linker histone, cluster member

decreases expression

hydroquinone results in decreased expression of H1-4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

H1.5 linker histone, cluster member

decreases expression

hydroquinone results in decreased expression of H1-5 mRNA

NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160

G

H2A clustered histone 12

decreases expression

hydroquinone results in decreased expression of H2AC12 mRNA

NCBI chr17:42,486,415...42,486,880
Ensembl chr17:42,486,415...42,486,941

G

H2A clustered histone 18

decreases expression

hydroquinone results in decreased expression of H2AC18 mRNA

NCBI chr 2:183,808,398...183,808,992

G

H2A clustered histone 20

decreases expression

hydroquinone results in decreased expression of H2AC20 mRNA

NCBI chr 2:183,779,879...183,780,357

G

H2A clustered histone 21

decreases expression

hydroquinone results in decreased expression of H2AC21 mRNA

NCBI chr 2:183,779,355...183,779,788

G

H2A.X variant histone

multiple interactions
increases expression
increases phosphorylation
affects localization

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of H2AX protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
hydroquinone results in increased phosphorylation of H2AX protein
hydroquinone affects the localization of H2AX protein modified form
hydroquinone results in increased expression of H2AX protein; hydroquinone results in increased expression of H2AX protein alternative form

PMID:17875398 PMID:18835433 PMID:20036648 PMID:21267443 PMID:22687461 More...

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

H4 clustered histone 14

decreases expression

hydroquinone results in decreased expression of H4C2 mRNA

NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048

G

histone H4C like 1

decreases expression

hydroquinone results in decreased expression of H4C6 mRNA

NCBI chr17:41,368,743...41,426,735

G

H1.3 linker histone, cluster member

decreases expression

hydroquinone results in decreased expression of H1-3 mRNA

NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334

G

hemoglobin alpha, adult chain 2

multiple interactions

hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene]

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin subunit beta

multiple interactions
decreases methylation

Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]
hydroquinone results in decreased methylation of HBB promoter

PMID:21414390 PMID:23973255 PMID:37329354

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

hemoglobin, beta adult major chain

multiple interactions

hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene]

NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012

G

heparin-binding EGF-like growth factor

increases expression

hydroquinone results in increased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

hemoglobin subunit gamma 1

multiple interactions

hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene]

NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425

G

HMG-box transcription factor 1

multiple interactions

hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene]

NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787

G

histone deacetylase 1

increases expression
multiple interactions

hydroquinone results in increased expression of HDAC1 mRNA; hydroquinone results in increased expression of HDAC1 protein
trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC1 mRNA]

PMID:27220438 PMID:30448557

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

G

histone deacetylase 2

increases expression
multiple interactions

hydroquinone results in increased expression of HDAC2 mRNA; hydroquinone results in increased expression of HDAC2 protein
trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC2 mRNA]

PMID:27220438 PMID:30448557

NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609

G

histone deacetylase 9

increases expression

hydroquinone results in increased expression of HDAC9 mRNA

NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333

G

homeostatic iron regulator

decreases expression

hydroquinone results in decreased expression of HFE mRNA

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

G

histone cluster 1, H4m

decreases expression

hydroquinone results in decreased expression of H4C1 mRNA

NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958

G

Holliday junction recognition protein

decreases expression

hydroquinone results in decreased expression of HJURP mRNA

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

hydroxymethylbilane synthase

multiple interactions

decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]

PMID:21414390 PMID:23973255

NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957

G

high mobility group box 2

decreases expression

hydroquinone results in decreased expression of HMGB2 mRNA

NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140

G

heme oxygenase 1

increases expression
multiple interactions

hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; AG 1879 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; bisindolylmaleimide I inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Cysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; [Resveratrol co-treated with hydroquinone] results in increased expression of HMOX1 protein; ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; Resveratrol promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]

PMID:17464197 PMID:21059386 PMID:23290930 PMID:28645578 PMID:29508652 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

Hoxa transcript antisense RNA, myeloid-specific 1

multiple interactions
affects expression
affects methylation

Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]

NCBI chr 4:81,258,793...81,262,291

G

HRas proto-oncogene, GTPase

multiple interactions
affects expression

3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]
hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

hydroxysteroid (17-beta) dehydrogenase 2

increases expression

hydroquinone results in increased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

heat shock protein family A (Hsp70) member 13

increases expression

hydroquinone results in increased expression of HSPA13 mRNA

NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895

G

heat shock protein family A (Hsp70) member 2

increases expression

hydroquinone results in increased expression of HSPA2 mRNA

NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287

G

heat shock protein family A (Hsp70) member 5

increases expression
multiple interactions

hydroquinone results in increased expression of HSPA5 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]

PMID:24053669 PMID:36646296 PMID:37148176

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

5-hydroxytryptamine receptor 1A

decreases expression

hydroquinone results in decreased expression of HTR1A protein

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 1B

decreases expression

hydroquinone results in decreased expression of HTR1B protein

NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549

G

HYLS1, centriolar and ciliogenesis associated

decreases expression

hydroquinone results in decreased expression of HYLS1 mRNA

NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760

G

inhibitor of DNA binding 1

increases expression

hydroquinone results in increased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 3

decreases expression

hydroquinone results in decreased expression of ID3 mRNA

NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349

G

inhibitor of DNA binding 4

increases expression

hydroquinone results in increased expression of ID4 mRNA

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

immediate early response 3

increases expression

hydroquinone results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon-induced protein 44

decreases expression

hydroquinone results in decreased expression of IFI44 mRNA

NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844

G

interferon-induced protein 44-like

decreases expression

hydroquinone results in decreased expression of IFI44L mRNA

NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359

G

interferon induced with helicase C domain 1

decreases expression

hydroquinone results in decreased expression of IFIH1 mRNA

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

interferon-induced protein with tetratricopeptide repeats 3

decreases expression

hydroquinone results in decreased expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

interferon induced transmembrane protein 1

decreases expression

hydroquinone results in decreased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

interferon gamma

multiple interactions

hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide]

PMID:3137358 PMID:7884313 PMID:22465845

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon-related developmental regulator 1

increases expression

hydroquinone results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

insulin-like growth factor 1

multiple interactions

IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 3

decreases expression

hydroquinone results in decreased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

inhibitor of nuclear factor kappa B kinase subunit beta

multiple interactions

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein]

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 10

multiple interactions
increases secretion

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
hydroquinone results in increased secretion of IL10 protein
hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]

PMID:17464197 PMID:17572062 PMID:23559866

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 12B

multiple interactions
increases expression

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
hydroquinone results in increased expression of IL12B mRNA

PMID:15894107 PMID:17464197

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

G

interleukin 15

decreases secretion

hydroquinone results in decreased secretion of IL15 protein

NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820

G

interleukin 17A

increases secretion

hydroquinone results in increased secretion of IL17A protein

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 18

multiple interactions
increases secretion

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

multiple interactions
increases expression
decreases cleavage

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]
hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein
hydroquinone results in decreased cleavage of IL1A protein

PMID:1868253 PMID:8548860 PMID:9118901 PMID:28836394 PMID:31256213

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

decreases cleavage
multiple interactions
increases expression
decreases secretion

hydroquinone results in decreased cleavage of IL1B protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; hydroquinone results in increased expression of and results in increased secretion of IL1B protein
hydroquinone results in increased expression of IL1B mRNA
hydroquinone results in decreased secretion of IL1B protein
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]

PMID:8548860 PMID:9118901 PMID:17464197 PMID:19148301 PMID:22717997 More...

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 family member 10

increases expression

hydroquinone results in increased expression of IL1F10 mRNA

NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439

G

interleukin 1 receptor antagonist

increases secretion

hydroquinone results in increased secretion of IL1RN protein

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 2

multiple interactions

hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 23 subunit alpha

multiple interactions

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA]

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 33

decreases expression

hydroquinone results in decreased expression of IL33 mRNA

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 36, gamma

increases expression

hydroquinone results in increased expression of IL36G mRNA

NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480

G

interleukin 36 receptor antagonist

increases expression

hydroquinone results in increased expression of IL36RN mRNA

NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016

G

interleukin 4

multiple interactions

hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein]

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6

multiple interactions
decreases secretion

[COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
[hydroquinone co-treated with TNF protein] results in increased secretion of IL6 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone results in decreased secretion of IL6 protein

PMID:17464197 PMID:19148301 PMID:20054000 PMID:22302391 PMID:22717997 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inhibin subunit beta A

increases expression

hydroquinone results in increased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

inhibin subunit beta E

decreases expression

hydroquinone results in decreased expression of INHBE mRNA

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

inositol polyphosphate-4-phosphatase type II B

increases expression

hydroquinone results in increased expression of INPP4B mRNA

NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634

G

interleukin-1 receptor-associated kinase 1

decreases expression

hydroquinone results in decreased expression of IRAK1 mRNA

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

G

interferon regulatory factor 3

multiple interactions

hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [TICAM1 protein results in increased phosphorylation of IRF3 protein]

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

G

insulin receptor substrate 1

decreases expression

hydroquinone results in decreased expression of IRS1 mRNA

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

ISG15 ubiquitin-like modifier

decreases expression

hydroquinone results in decreased expression of ISG15 mRNA

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

G

integrin subunit beta 1

decreases activity
decreases expression

hydroquinone results in decreased activity of ITGB1 protein
hydroquinone results in decreased expression of ITGB1 mRNA
hydroquinone results in decreased expression of ITGB1 protein

PMID:17464197 PMID:19148301

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

integrin subunit beta 2

decreases expression
increases expression

hydroquinone results in decreased expression of ITGB2 protein
hydroquinone results in decreased expression of ITGB2 mRNA
hydroquinone results in increased expression of ITGB2 protein

PMID:17464197 PMID:19148301 PMID:21664406

NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600

G

integrin subunit beta 3

increases expression

hydroquinone results in increased expression of ITGB3 protein

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

G

involucrin

increases expression

hydroquinone results in increased expression of IVL mRNA; hydroquinone results in increased expression of IVL protein

PMID:25240866 PMID:31256213

NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100

G

jagged canonical Notch ligand 1

decreases expression

hydroquinone results in decreased expression of JAG1 mRNA

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

joining chain of multimeric IgA and IgM

decreases expression

hydroquinone results in decreased expression of JCHAIN mRNA

NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298

G

Jrk helix-turn-helix protein

decreases expression

hydroquinone results in decreased expression of JRK mRNA

NCBI chr 7:106,590,662...106,595,345
Ensembl chr 7:106,589,484...106,596,371

G

Jun proto-oncogene, AP-1 transcription factor subunit

affects localization
multiple interactions
increases phosphorylation

hydroquinone affects the localization of JUN protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; JUN protein affects the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]

PMID:23288922 PMID:23791922 PMID:26807887

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

kelch repeat and BTB domain containing 6

decreases expression

hydroquinone results in decreased expression of KBTBD6 mRNA

NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453

G

kelch repeat and BTB domain containing 7

decreases expression

hydroquinone results in decreased expression of KBTBD7 mRNA

NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687

G

potassium inwardly-rectifying channel, subfamily J, member 15

decreases expression

hydroquinone results in decreased expression of KCNJ15 mRNA

NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952

G

lysine demethylase 6A

decreases expression

hydroquinone results in decreased expression of KDM6A mRNA

NCBI chr X:4,337,466...4,477,100
Ensembl chr X:4,337,750...4,477,062

G

Kelch-like ECH-associated protein 1

decreases expression

hydroquinone results in decreased expression of KEAP1 protein

PMID:23290930 PMID:36646296

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KICSTOR subunit 2

decreases expression

hydroquinone results in decreased expression of KICS2 mRNA

NCBI chr 7:57,284,213...57,299,070
Ensembl chr 7:57,284,192...57,297,486

G

kinesin family member 18A

decreases expression

hydroquinone results in decreased expression of KIF18A mRNA

NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582

G

KIT ligand

increases expression

hydroquinone results in increased expression of KITLG mRNA

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

G

KLF transcription factor 2

increases expression

hydroquinone results in increased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KLF transcription factor 4

multiple interactions

[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

KLF transcription factor 7

increases expression

hydroquinone results in increased expression of KLF7 mRNA

NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261

G

kelch-like family member 31

decreases expression

hydroquinone results in decreased expression of KLHL31 mRNA

NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873

G

kallikrein related-peptidase 6

increases expression

hydroquinone results in increased expression of KLK6 mRNA

NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121

G

killer cell lectin like receptor G2

decreases expression

hydroquinone results in decreased expression of KLRG2 mRNA

NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147

G

lysine methyltransferase 2A

decreases response to substance
multiple interactions

KMT2A mutant form results in decreased susceptibility to hydroquinone
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA

NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181

G

KRAS proto-oncogene, GTPase

multiple interactions
increases expression
affects expression

[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein
hydroquinone results in increased expression of KRAS protein
hydroquinone affects the expression of KRAS mRNA

PMID:27515134 PMID:28444915

NCBI chr 4:178,185,418...178,218,484

G

keratin 13

decreases expression

hydroquinone results in decreased expression of KRT13 mRNA

NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084

G

keratin 19

decreases expression

hydroquinone results in decreased expression of KRT19 mRNA

NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799

G

keratin 23

increases expression

hydroquinone results in increased expression of KRT23 mRNA

NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983

G

keratin 24

decreases expression

hydroquinone results in decreased expression of KRT24 mRNA

NCBI chr10:84,232,163...84,237,299
Ensembl chr10:84,232,164...84,237,299

G

keratin 78

increases expression

hydroquinone results in increased expression of KRT78 mRNA

NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021

G

keratin 80

increases expression

hydroquinone results in increased expression of KRT80 mRNA

NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508

G

laminin subunit alpha 4

increases expression
multiple interactions

hydroquinone results in increased expression of LAMA4 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]

NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347

G

LIM and SH3 protein 1

affects expression

hydroquinone affects the expression of LASP1 protein

NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292

G

lipocalin 2

increases expression

hydroquinone results in increased expression of LCN2 mRNA

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

lymphoid enhancer binding factor 1

multiple interactions
decreases expression

hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]
hydroquinone results in decreased expression of LEF1 protein

NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794

G

LEM domain containing 1

decreases expression

hydroquinone results in decreased expression of LEMD1 mRNA

NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948

G

galectin 9

increases expression

hydroquinone results in increased expression of LGALS9 mRNA

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

G

galectin-like

increases expression

hydroquinone results in increased expression of LGALSL mRNA

NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980

G

leucine-rich repeat-containing G protein-coupled receptor 4

decreases expression

hydroquinone results in decreased expression of LGR4 mRNA

NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899

G

lipase G, endothelial type

increases expression

hydroquinone results in increased expression of LIPG mRNA

NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260

G

lamin A/C

affects expression

hydroquinone affects the expression of LMNA protein

NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423

G

loricrin cornified envelope precursor protein

increases expression

hydroquinone results in increased expression of LORICRIN mRNA
hydroquinone results in increased expression of LORICRIN protein

PMID:25240866 PMID:31256213

NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807

G

lipoprotein lipase

multiple interactions

[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

leucine rich repeat containing 27

decreases expression

hydroquinone results in decreased expression of LRRC27 mRNA

NCBI chr 1:194,004,967...194,035,087
Ensembl chr 1:194,005,182...194,035,084

G

leucine rich repeat containing 71

increases expression

hydroquinone results in increased expression of LRRC71 mRNA

NCBI chr 2:173,194,792...173,207,448
Ensembl chr 2:173,194,792...173,207,448

G

leucine-rich repeats and IQ motif containing 3

decreases expression

hydroquinone results in decreased expression of LRRIQ3 mRNA

NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339

G

lanosterol synthase

decreases expression

hydroquinone results in decreased expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

lymphocyte antigen 6 family member E

decreases expression

hydroquinone results in decreased expression of LY6E mRNA

NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689

G

lymphocyte antigen 96

increases expression

hydroquinone results in increased expression of LY96 mRNA

NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386

G

Ly6/Plaur domain containing 5

increases expression

hydroquinone results in increased expression of LYPD5 mRNA

NCBI chr 1:79,929,818...79,941,791
Ensembl chr 1:79,935,240...79,941,039

G

macroH2A.1 histone

decreases expression

hydroquinone results in decreased expression of MACROH2A1 protein

NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072

G

MAF bZIP transcription factor F

increases expression

hydroquinone results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

membrane associated guanylate kinase, WW and PDZ domain containing 1

multiple interactions

[hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein]

NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691

G

microtubule-associated protein 1B

increases expression

hydroquinone results in increased expression of MAP1B mRNA

NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317

G

microtubule-associated protein 1 light chain 3 alpha

multiple interactions

Chloroquine inhibits the reaction [hydroquinone results in increased degradation of MAP1LC3A protein]; hydroquinone affects the localization of and results in increased degradation of MAP1LC3A protein

NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670

G

microtubule-associated protein 1 light chain 3 beta

increases lipidation
multiple interactions

hydroquinone results in increased lipidation of MAP1LC3B protein
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Sirolimus promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

mitogen activated protein kinase kinase 1

multiple interactions

MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

MAP7 domain containing 2

decreases expression

hydroquinone results in decreased expression of MAP7D2 mRNA

NCBI chr X:35,372,453...35,488,073
Ensembl chr X:35,372,700...35,488,091

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation
decreases phosphorylation

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]
hydroquinone results in increased phosphorylation of MAPK1 protein

PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 14

multiple interactions
increases phosphorylation

Chloroquine inhibits the reaction [hydroquinone results in increased phosphorylation of MAPK14 protein]

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation
decreases phosphorylation

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]
hydroquinone results in increased phosphorylation of MAPK3 protein

PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

increases phosphorylation
multiple interactions

hydroquinone results in increased phosphorylation of MAPK8 protein
hydroquinone results in decreased expression of and results in increased phosphorylation of MAPK8 protein

PMID:23791922 PMID:37148176

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

membrane associated ring-CH-type finger 3

increases expression

hydroquinone results in increased expression of MARCHF3 mRNA

NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150

G

methyl-CpG binding domain protein 2

decreases expression
multiple interactions
increases expression

hydroquinone results in decreased expression of MBD2 mRNA
PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]

PMID:22245671 PMID:30448557

NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794

G

muscleblind-like splicing regulator 3

decreases expression

hydroquinone results in decreased expression of MBNL3 mRNA

NCBI chr X:130,641,942...130,737,179
Ensembl chr X:130,648,538...130,737,056

G

membrane bound O-acyltransferase domain containing 2

increases expression

hydroquinone results in increased expression of MBOAT2 mRNA

NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485

G

melanocortin 1 receptor

decreases expression

hydroquinone results in decreased expression of MC1R mRNA

NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192

G

MCL1 apoptosis regulator, BCL2 family member

increases expression
multiple interactions

hydroquinone results in increased expression of MCL1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; [hydroquinone co-treated with WEHI-539] results in decreased expression of MCL1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

G

multiple C2 and transmembrane domain containing 1

increases expression

hydroquinone results in increased expression of MCTP1 mRNA

NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833

G

multiple C2 and transmembrane domain containing 2

decreases expression

hydroquinone results in decreased expression of MCTP2 mRNA

NCBI chr 1:125,769,932...126,002,886
Ensembl chr 1:125,771,233...126,002,928

G

MDM2 proto-oncogene

increases expression

hydroquinone results in increased expression of MDM2 mRNA

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

methyltransferase 21A, HSPA lysine

decreases expression

hydroquinone results in decreased expression of METTL21A mRNA

NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550

G

microsomal glutathione S-transferase 1

increases expression

hydroquinone results in increased expression of MGST1 mRNA

NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892

G

midline 1

decreases expression

hydroquinone results in decreased expression of MID1 mRNA

NCBI chr X:24,116,674...24,491,205
Ensembl chr X:24,120,293...24,248,353

G

microRNA 106b

decreases expression

hydroquinone results in decreased expression of MIR106B mRNA

NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425

G

microRNA 107

decreases expression

hydroquinone results in decreased expression of MIR107 mRNA

NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853

G

microRNA 122

multiple interactions
decreases expression

ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; MIR122 mRNA affects the reaction [hydroquinone results in decreased expression of and results in increased secretion of TNF protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]

NCBI chr18:58,758,703...58,758,787

G

microRNA 126a

decreases expression

hydroquinone results in decreased expression of MIR126 mRNA

NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180

G

microRNA 130a

decreases expression

hydroquinone results in decreased expression of MIR130A mRNA

NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629

G

microRNA 146a

affects expression
multiple interactions

hydroquinone affects the expression of MIR146A mRNA
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MIR146A mRNA]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

G

microRNA 155

multiple interactions
increases expression

Doxorubicin promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; trichostatin A promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]

NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718

G

microRNA 15b

decreases expression

hydroquinone results in decreased expression of MIR15B mRNA

NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297

G

microRNA 17

decreases expression

hydroquinone results in decreased expression of MIR17 mRNA

NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712

G

microRNA 185

decreases expression

hydroquinone results in decreased expression of MIR185 mRNA

NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795

G

microRNA 18a

decreases expression

hydroquinone results in decreased expression of MIR18A mRNA

NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860

G

microRNA 19a

decreases expression

hydroquinone results in decreased expression of MIR19A mRNA

NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993

G

microRNA 20a

decreases expression

hydroquinone results in decreased expression of MIR20A mRNA

NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168

G

microRNA 20b

decreases expression

hydroquinone results in decreased expression of MIR20B mRNA

NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282

G

microRNA 223

decreases expression

hydroquinone results in decreased expression of MIR223 mRNA

NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996

G

microRNA 25

decreases expression
multiple interactions

hydroquinone results in decreased expression of MIR25; hydroquinone results in decreased expression of MIR25 mRNA
[hydroquinone results in decreased expression of MIR25] which results in increased expression of NOX4 protein; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of MIR25]

PMID:28733890 PMID:35302183

NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015

G

microRNA 29a

decreases expression

hydroquinone results in decreased expression of MIR29A mRNA

NCBI chr 4:59,650,608...59,650,695

G

microRNA 342

decreases expression

hydroquinone results in decreased expression of MIR342 mRNA

NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367

G

microRNA 451a

increases expression
multiple interactions

hydroquinone results in increased expression of MIR451A mRNA
hydroquinone affects the reaction [Hemin results in increased expression of MIR451A mRNA]

NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591

G

microRNA 486

multiple interactions

hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; hydroquinone inhibits the reaction [Hemin results in increased expression of MIR486-1 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]

G

microRNA 494

decreases expression

hydroquinone results in decreased expression of MIR494 mRNA

NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793

G

microRNA 8

decreases expression
multiple interactions

hydroquinone results in decreased expression of MIR7-2
hydroquinone inhibits the reaction [MIR7-2 binds to RB1 protein]; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of RB1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCND1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCNE1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK2 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK4 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of E2F1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased phosphorylation of RB1 protein]

NCBI chr 1:132,806,420...132,806,514
Ensembl chr 1:132,806,420...132,806,514

G

microRNA 93

decreases expression

hydroquinone results in decreased expression of MIR93 mRNA

NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221

G

microRNA let-7g

decreases expression

hydroquinone results in decreased expression of MIRLET7G mRNA

NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388

G

matrix metallopeptidase 1

increases expression

hydroquinone results in increased expression of MMP1 mRNA

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

matrix metallopeptidase 14

multiple interactions

[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 15

affects expression

hydroquinone affects the expression of MMP15 mRNA

NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943

G

matrix metallopeptidase 2

decreases activity
multiple interactions

hydroquinone results in decreased activity of MMP2 protein
[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]

PMID:16936130 PMID:18055817

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 3

affects expression
increases expression

hydroquinone affects the expression of MMP3 mRNA
hydroquinone results in increased expression of MMP3 mRNA

PMID:15452088 PMID:31256213

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

multiple interactions
increases expression
increases secretion

CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]
hydroquinone results in increased expression of MMP9 mRNA; hydroquinone results in increased expression of MMP9 protein

PMID:17669387 PMID:26807887 PMID:27515134 PMID:33771647 PMID:33932074 More...

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

MOB kinase activator 3B

decreases expression

hydroquinone results in decreased expression of MOB3B mRNA

NCBI chr 5:49,546,254...49,737,934
Ensembl chr 5:49,545,815...49,737,934

G

MPL proto-oncogene, thrombopoietin receptor

multiple interactions
decreases methylation
increases expression

[trichostatin A co-treated with Decitabine] promotes the reaction [hydroquinone results in increased expression of MPL mRNA]; Decitabine promotes the reaction [hydroquinone results in increased expression of MPL mRNA]
hydroquinone results in decreased methylation of MPL gene

NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797

G

myeloperoxidase

multiple interactions
increases chemical synthesis
increases oxidation

[[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein; [[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone; [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]; [MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone; [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
MPO protein results in increased chemical synthesis of hydroquinone
MPO protein results in increased oxidation of hydroquinone

PMID:1666626 PMID:10994872 PMID:15777082 PMID:15935818 PMID:31248982

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

myelin protein zero-like 3

increases expression

hydroquinone results in increased expression of MPZL3 mRNA

NCBI chr 8:45,360,475...45,380,662
Ensembl chr 8:45,349,054...45,380,662

G

maestro heat-like repeat family member 5

decreases expression

hydroquinone results in decreased expression of MROH5 mRNA

NCBI chr 7:105,662,737...105,737,820
Ensembl chr 7:105,662,744...105,730,060

G

mitochondrially encoded cytochrome c oxidase I

increases expression

hydroquinone results in increased expression of COX1 mRNA; hydroquinone results in increased expression of COX1 protein

NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

metallothionein 1

increases expression

hydroquinone results in increased expression of MT1 mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 2A

multiple interactions
increases expression

[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of MT2A mRNA]

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

decreases expression

hydroquinone results in decreased expression of MTHFD1 mRNA

NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372

G

mechanistic target of rapamycin kinase

decreases phosphorylation
multiple interactions

hydroquinone results in decreased phosphorylation of MTOR protein
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Sirolimus promotes the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

microtubule associated scaffold protein 1

decreases expression

hydroquinone results in decreased expression of MTUS1 mRNA

NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793

G

MX dynamin like GTPase 1

decreases expression

hydroquinone results in decreased expression of MX1 mRNA

NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507

G

MYB proto-oncogene, transcription factor

decreases expression

hydroquinone results in decreased expression of MYB mRNA

NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057

G

MYC proto-oncogene, bHLH transcription factor

multiple interactions
decreases expression

hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]
hydroquinone results in decreased expression of MYC mRNA

PMID:12749906 PMID:22245671

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

MYCL proto-oncogene, bHLH transcription factor

decreases expression

hydroquinone results in decreased expression of MYCL mRNA

NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582

G

myosin regulatory light chain interacting protein

decreases expression

hydroquinone results in decreased expression of MYLIP mRNA

NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295

G

myosin IF

decreases expression

hydroquinone results in decreased expression of MYO1F mRNA

NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911

G

NEDD4 binding protein 2-like 1

decreases expression

hydroquinone results in decreased expression of N4BP2L1 mRNA

NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257

G

neutrophil cytosolic factor 2

increases expression

hydroquinone results in increased expression of NCF2 mRNA

NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277

G

NEDD4 like E3 ubiquitin protein ligase

decreases expression

hydroquinone results in decreased expression of NEDD4L mRNA

NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137

G

neurofilament heavy chain

decreases expression

hydroquinone results in decreased expression of NEFH mRNA

NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351

G

neuraminidase 3

increases expression

hydroquinone results in increased expression of NEU3 mRNA

NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813

G

neuralized E3 ubiquitin protein ligase 1B

increases expression

hydroquinone results in increased expression of NEURL1B mRNA

NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119

G

nuclear factor of activated T-cells 2

increases expression

hydroquinone results in increased expression of NFATC2 mRNA

NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325

G

nuclear factor, erythroid 2

multiple interactions

hydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA]

NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108

G

NFE2 like bZIP transcription factor 2

multiple interactions
increases expression
decreases expression
increases activity

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of NFE2L2 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]
hydroquinone results in increased expression of NFE2L2 mRNA; hydroquinone results in increased expression of NFE2L2 protein
hydroquinone results in decreased expression of NFE2L2 mRNA

PMID:21059386 PMID:21643505 PMID:23290930 PMID:28645578 PMID:31967339 More...

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

multiple interactions
decreases expression
increases expression

hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
hydroquinone results in decreased expression of NFKB1 mRNA
hydroquinone results in increased expression of NFKB1 protein

PMID:15894107 PMID:30090394 PMID:30448557

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nuclear factor kappa B subunit 2

decreases expression

hydroquinone results in decreased expression of NFKB2 mRNA

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

G

NFKB inhibitor alpha

multiple interactions
affects phosphorylation

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
hydroquinone affects the phosphorylation of NFKBIA protein
hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]

PMID:20054000 PMID:23288922 PMID:30090394

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor beta

decreases degradation

hydroquinone results in decreased degradation of NFKBIB protein

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

niban apoptosis regulator 1

increases expression

hydroquinone results in increased expression of NIBAN1 mRNA

NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729

G

nidogen 1

decreases expression

hydroquinone results in decreased expression of NID1 mRNA

NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267

G

NIPA-like domain containing 3

decreases expression

hydroquinone results in decreased expression of NIPAL3 mRNA

NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351

G

NLR family, pyrin domain containing 3

increases expression
multiple interactions

hydroquinone results in increased expression of NLRP3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

nitric oxide synthase 2

multiple interactions
increases expression
decreases expression

hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
hydroquinone results in increased expression of NOS2 mRNA
hydroquinone results in decreased expression of NOS2 mRNA; hydroquinone results in decreased expression of NOS2 protein

PMID:15831208 PMID:17464197 PMID:19148301 PMID:23290930

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

NADPH oxidase 4

multiple interactions
increases expression

[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of NOX4 protein; [hydroquinone results in decreased expression of MIR25] which results in increased expression of NOX4 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 mRNA; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 protein; [WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 mRNA; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of PARP1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in increased expression of NOX4 mRNA]
hydroquinone results in increased expression of NOX4 mRNA; hydroquinone results in increased expression of NOX4 protein

PMID:35302183 PMID:35561756

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions
decreases response to substance

hydroquinone results in increased expression of NQO1 mRNA; hydroquinone results in increased expression of NQO1 protein
FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein
NQO1 protein results in decreased susceptibility to hydroquinone
ferric chloride promotes the reaction [hydroquinone results in increased expression of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NQO1 protein]

PMID:8652659 PMID:10368308 PMID:10393963 PMID:19525446 PMID:21059386 More...

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 4, group A, member 2

decreases expression

hydroquinone results in decreased expression of NR4A2 mRNA

NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877

G

NRAS proto-oncogene, GTPase

decreases expression

hydroquinone results in decreased expression of NRAS mRNA

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

G

nuclear receptor binding protein 2

increases expression

hydroquinone results in increased expression of NRBP2 mRNA

NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230

G

nudix hydrolase 16

decreases expression

hydroquinone results in decreased expression of NUDT16 mRNA

NCBI chr 8:105,739,927...105,741,982
Ensembl chr 8:105,739,623...105,741,998

G

NACHT and WD repeat domain containing 2

increases expression

hydroquinone results in increased expression of NWD2 mRNA

NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299

G

2'-5' oligoadenylate synthetase 1A

decreases expression

hydroquinone results in decreased expression of OAS1 mRNA

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

G

2'-5' oligoadenylate synthetase 2

decreases expression

hydroquinone results in decreased expression of OAS2 mRNA

NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371

G

2'-5'-oligoadenylate synthetase-like

increases expression

hydroquinone results in increased expression of OASL mRNA

PMID:29221148 PMID:31256213

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

G

occludin

multiple interactions

hydroquinone results in decreased degradation of and results in increased expression of OCLN protein

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

oleoyl-ACP hydrolase

increases expression

hydroquinone results in increased expression of OLAH mRNA

NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518

G

olfactory receptor family 2 subfamily C member 1

decreases expression

hydroquinone results in decreased expression of OR2C1 mRNA

NCBI chr10:11,682,890...11,683,828
Ensembl chr10:11,681,001...11,692,105

G

ovo like transcriptional repressor 1

increases expression

hydroquinone results in increased expression of OVOL1 mRNA

NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831

G

purinergic receptor P2X 4

increases expression

hydroquinone results in increased expression of P2RX4 mRNA

NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253

G

proliferation-associated 2G4

affects expression

hydroquinone affects the expression of PA2G4 protein

NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331

G

poly(A) binding protein, cytoplasmic 4-like

decreases expression

hydroquinone results in decreased expression of PABPC4L mRNA

NCBI chr 2:129,807,755...129,809,745
Ensembl chr 2:129,807,755...129,809,745

G

phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

decreases expression

hydroquinone results in decreased expression of PAICS mRNA

NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635

G

poly(A) binding protein interacting protein 2B

decreases expression

hydroquinone results in decreased expression of PAIP2B mRNA

NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379

G

palmdelphin

decreases expression

hydroquinone results in decreased expression of PALMD mRNA

NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519

G

poly (ADP-ribose) polymerase 1

increases cleavage
increases degradation
decreases expression
affects response to substance
increases expression
increases response to substance
affects expression
multiple interactions

hydroquinone results in increased cleavage of PARP1 protein
hydroquinone results in increased degradation of PARP1 protein
hydroquinone results in decreased expression of PARP1 protein
PARP1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of PARP1 protein
PARP1 protein results in increased susceptibility to hydroquinone
hydroquinone affects the expression of PARP1 protein
3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; [ABT-737 co-treated with hydroquinone] results in increased cleavage of PARP1 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; ABT-737 inhibits the reaction [hydroquinone affects the localization of PARP1 protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; hydroquinone results in increased expression of and affects the localization of PARP1 protein; hydroquinone results in increased expression of and results in increased cleavage of PARP1 protein; Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of PARP1 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of TJP2 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of TP53 protein]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]

PMID:19064679 PMID:23288922 PMID:26047893 PMID:26335980 PMID:26822515 More...

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

poly (ADP-ribose) polymerase family, member 9

decreases expression

hydroquinone results in decreased expression of PARP9 mRNA

NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455

G

PBX homeobox 1

decreases expression

hydroquinone results in decreased expression of PBX1 mRNA

NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

hydroquinone results in increased expression of PCK2 mRNA

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

G

programmed cell death 4

decreases expression

hydroquinone results in decreased expression of PDCD4 mRNA

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

phosphodiesterase 11A

decreases expression

hydroquinone results in decreased expression of PDE11A mRNA

NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:60,913,562...61,297,158

G

phosphodiesterase 4B

decreases expression

hydroquinone results in decreased expression of PDE4B mRNA

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

platelet derived growth factor receptor beta

multiple interactions

[hydroquinone co-treated with Hemin] affects the expression of PDGFRB mRNA

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

3-phosphoinositide dependent protein kinase-1

decreases activity

hydroquinone metabolite results in decreased activity of PDPK1 protein; hydroquinone results in decreased activity of PDPK1 protein

NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623

G

platelet and endothelial cell adhesion molecule 1

increases expression

hydroquinone results in increased expression of PECAM1 protein

NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116

G

paternally expressed 3

decreases expression

hydroquinone results in decreased expression of PEG3 mRNA

NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671

G

6-phosphogluconolactonase

affects expression

hydroquinone affects the expression of PGLS protein

NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803

G

peptidoglycan recognition protein 4

increases expression

hydroquinone results in increased expression of PGLYRP4 mRNA

NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251

G

pleckstrin homology-like domain, family A, member 1

increases expression

hydroquinone results in increased expression of PHLDA1 mRNA

NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

decreases expression

hydroquinone results in decreased expression of PIK3C3 mRNA

NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048

G

phosphoinositide-3-kinase interacting protein 1

decreases expression

hydroquinone results in decreased expression of PIK3IP1 mRNA

NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608

G

phosphoinositide-3-kinase regulatory subunit 1

multiple interactions

Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

Pim-1 proto-oncogene, serine/threonine kinase

increases expression

hydroquinone results in increased expression of PIM1 mRNA

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

G

paired-like homeodomain 2

decreases expression

hydroquinone results in decreased expression of PITX2 mRNA

NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293

G

cAMP-dependent protein kinase inhibitor alpha

decreases expression

hydroquinone results in decreased expression of PKIA mRNA

NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282

G

plakophilin 2

increases expression

hydroquinone results in increased expression of PKP2 mRNA

NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730

G

phosphatidylinositol-specific phospholipase C, X domain containing 1

increases expression

hydroquinone results in increased expression of PLCXD1 mRNA

NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392

G

phospholipase D1

decreases expression

hydroquinone results in decreased expression of PLD1 mRNA

NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692

G

plasmolipin

decreases expression

hydroquinone results in decreased expression of PLLP mRNA

NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892

G

phorbol-12-myristate-13-acetate-induced protein 1

multiple interactions

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of PMAIP1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; mithramycin A inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 mRNA]; mithramycin A inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

polyamine modulated factor 1 binding protein 1

increases expression

hydroquinone results in increased expression of PMFBP1 mRNA

NCBI chr19:37,458,126...37,507,880
Ensembl chr19:37,458,108...37,507,879

G

DNA polymerase eta

multiple interactions
affects response to substance

POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
POLH protein affects the susceptibility to hydroquinone

NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723

G

RNA polymerase I subunit B

decreases expression

hydroquinone results in decreased expression of POLR1B mRNA

NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379

G

peroxisome proliferator-activated receptor delta

increases expression

hydroquinone results in increased expression of PPARD mRNA

NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

multiple interactions

[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

increases expression

hydroquinone results in increased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein phosphatase 1, regulatory subunit 15A

increases expression

hydroquinone results in increased expression of PPP1R15A mRNA

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

protein phosphatase 2 catalytic subunit alpha

multiple interactions
increases expression

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; Chloroquine inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]

PMID:23288922 PMID:30567741 PMID:35302183

NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862

G

protein phosphatase 2, regulatory subunit B', alpha

multiple interactions

PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]

NCBI chr13:102,931,264...102,975,661
Ensembl chr13:102,931,264...102,975,661

G

protein phosphatase targeting COQ7

decreases expression

hydroquinone results in decreased expression of PPTC7 mRNA

NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339

G

PR/SET domain 1

increases expression

hydroquinone results in increased expression of PRDM1 mRNA

NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488

G

peroxiredoxin 1

increases expression

hydroquinone results in increased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

protein kinase C, gamma

affects localization

hydroquinone affects the localization of PRKCG protein

NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384

G

protein kinase, DNA-activated, catalytic subunit

increases expression

hydroquinone results in increased expression of PRKDC mRNA; hydroquinone results in increased expression of PRKDC protein

PMID:20036648 PMID:23940708

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

G

proline rich 9

increases expression

hydroquinone results in increased expression of PRR9 mRNA

NCBI chr 2:177,599,483...177,600,849
Ensembl chr 2:177,599,483...177,600,849

G

serine protease 3

increases expression

hydroquinone results in increased expression of PRSS3 mRNA

NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562

G

prosaposin-like 1

increases expression

hydroquinone results in increased expression of PSAPL1 mRNA

NCBI chr14:74,544,646...74,547,206
Ensembl chr14:74,544,646...74,547,206

G

proline and serine rich coiled-coil 1

decreases expression

hydroquinone results in decreased expression of PSRC1 mRNA

NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874

G

prostaglandin reductase 2

decreases expression

hydroquinone results in decreased expression of PTGR2 mRNA

NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111

G

prostaglandin-endoperoxide synthase 2

increases expression

hydroquinone results in increased expression of PTGS2 mRNA

PMID:23290930 PMID:31256213

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine phosphatase, non-receptor type 2

multiple interactions

[[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein

NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627

G

PYD and CARD domain containing

multiple interactions
increases expression

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

G

glycogen phosphorylase B

increases expression

hydroquinone results in increased expression of PYGB mRNA

NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553

G

glutaminyl-peptide cyclotransferase

increases expression

hydroquinone results in increased expression of QPCT mRNA

NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711

G

RAB30, member RAS oncogene family

decreases expression

hydroquinone results in decreased expression of RAB30 mRNA

NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181

G

RAB3B, member RAS oncogene family

increases expression

hydroquinone results in increased expression of RAB3B mRNA

NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401

G

Rab7b, member RAS oncogene family

decreases expression

hydroquinone results in decreased expression of RAB7B mRNA

NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581

G

RAB GTPase activating protein 1-like

decreases expression

hydroquinone results in decreased expression of RABGAP1L mRNA

NCBI chr13:72,464,114...73,059,845
Ensembl chr13:72,468,110...73,059,984

G

Raf-1 proto-oncogene, serine/threonine kinase

increases expression

hydroquinone results in increased expression of RAF1 mRNA

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

G

RAP1A, member of RAS oncogene family

multiple interactions

[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAP1A protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]

NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501

G

Rap guanine nucleotide exchange factor 2

multiple interactions

[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]

NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247

G

Ras association domain family member 5

multiple interactions

[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein; hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein]

NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024

G

RB transcriptional corepressor 1

increases expression
decreases expression
multiple interactions

hydroquinone results in increased expression of RB protein; hydroquinone results in increased expression of RB1 mRNA
hydroquinone results in decreased expression of RB1 mRNA; hydroquinone results in decreased expression of RB1 protein
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; hydroquinone inhibits the reaction [MIR7-2 binds to RB1 protein]; hydroquinone results in decreased expression of and results in increased phosphorylation of RB1 protein; hydroquinone results in increased expression of and results in increased phosphorylation of RB1 protein; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of RB1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased phosphorylation of RB1 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]

PMID:26047893 PMID:30506647 PMID:33771647 PMID:33932074 PMID:37951342

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RANBP2-type and C3HC4-type zinc finger containing 1

increases expression

hydroquinone results in increased expression of RBCK1 mRNA

NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005

G

retinol dehydrogenase 12

increases expression

hydroquinone results in increased expression of RDH12 mRNA

NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388

G

reversion-inducing-cysteine-rich protein with kazal motifs

decreases expression

hydroquinone results in decreased expression of RECK mRNA

NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502

G

RecQ like helicase 4

increases expression

hydroquinone results in increased expression of RECQL4 mRNA

NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases phosphorylation
affects localization

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]; hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
hydroquinone affects the localization of RELA protein
hydroquinone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]

PMID:15894107 PMID:16928326 PMID:20054000 PMID:23288922 PMID:30090394 More...

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RALBP1 associated Eps domain containing 1

decreases expression

hydroquinone results in decreased expression of REPS1 mRNA

NCBI chr 1:12,697,742...12,775,562
Ensembl chr 1:12,697,747...12,775,561

G

raftlin lipid raft linker 1

increases expression

hydroquinone results in increased expression of RFTN1 mRNA

NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084

G

regulatory factor X5

decreases expression

hydroquinone results in decreased expression of RFX5 mRNA

NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717

G

regulator of G-protein signaling 17

increases expression

hydroquinone results in increased expression of RGS17 mRNA

NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609

G

Rh family, C glycoprotein

increases expression

hydroquinone results in increased expression of RHCG mRNA

NCBI chr 1:133,531,704...133,555,902
Ensembl chr 1:133,531,716...133,555,876

G

RIO kinase 2

decreases expression

hydroquinone results in decreased expression of RIOK2 mRNA

NCBI chr 1:58,103,132...58,119,397
Ensembl chr 1:58,103,084...58,120,512

G

ribonuclease A family member 4

decreases expression

hydroquinone results in decreased expression of RNASE4 mRNA

NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117

G

ribonuclease L

decreases expression

hydroquinone results in decreased expression of RNASEL mRNA

NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704

G

receptor tyrosine kinase-like orphan receptor 1

decreases expression

hydroquinone results in decreased expression of ROR1 mRNA

NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155

G

ribosomal protein S6 kinase A2

increases expression

hydroquinone results in increased expression of RPS6KA2 mRNA

NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739

G

repetin

increases expression

hydroquinone results in increased expression of RPTN mRNA

PMID:25240866 PMID:31256213

NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

hydroquinone results in increased expression of RRAD mRNA

NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417

G

ribosomal RNA processing 12

decreases expression

hydroquinone results in decreased expression of RRP12 mRNA

NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:240,672,382...240,706,018

G

RUNX family transcription factor 2

increases expression

hydroquinone results in increased expression of RUNX2 mRNA

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

S100 calcium binding protein A7A

decreases expression

hydroquinone results in decreased expression of S100A7A mRNA

NCBI chr 2:176,151,405...176,155,846
Ensembl chr 2:176,151,288...176,156,441

G

S100 calcium binding protein A9

increases expression

hydroquinone results in increased expression of S100A9 mRNA

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

S100 calcium binding protein B

multiple interactions

hydroquinone results in increased expression of and results in increased secretion of S100B protein

NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743

G

SATB homeobox 1

decreases expression

hydroquinone results in decreased expression of SATB1 mRNA

NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251

G

SH3 domain binding kinase 1

decreases expression

hydroquinone results in decreased expression of SBK1 mRNA

NCBI chr 1:180,807,092...180,851,910
Ensembl chr 1:180,807,099...180,851,885

G

scavenger receptor class A, member 3

decreases expression

hydroquinone results in decreased expression of SCARA3 mRNA

NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894

G

sec1 family domain containing 2

decreases expression

hydroquinone results in decreased expression of SCFD2 mRNA

NCBI chr14:33,683,348...34,008,232
Ensembl chr14:33,683,273...34,008,213

G

secretogranin V

increases expression

hydroquinone results in increased expression of SCG5 mRNA

NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463

G

short chain dehydrogenase/reductase family 9C, member 7

increases expression

hydroquinone results in increased expression of SDR9C7 mRNA

NCBI chr 7:63,703,788...63,720,325
Ensembl chr 7:63,707,071...63,721,480

G

SEC24 homolog D, COPII coat complex component

increases expression

hydroquinone results in increased expression of SEC24D mRNA

NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587

G

selenoprotein P

decreases expression

hydroquinone results in decreased expression of SELENOP mRNA

NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852

G

selectin P

increases expression

hydroquinone results in increased expression of SELP mRNA; hydroquinone results in increased expression of SELP protein

NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845

G

septin 6

decreases expression

hydroquinone results in decreased expression of SEPTIN6 mRNA

NCBI chr X:116,153,255...116,230,334
Ensembl chr X:116,153,255...116,230,115

G

serpin family A member 12

increases expression

hydroquinone results in increased expression of SERPINA12 mRNA

NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271

G

serpin family B member 9

increases expression

hydroquinone results in increased expression of SERPINB9 mRNA

NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230

G

serpin family E member 2

increases expression

hydroquinone results in increased expression of SERPINE2 mRNA

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

G

sestrin 1

increases expression

hydroquinone results in increased expression of SESN1 mRNA

NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697

G

sestrin 2

increases expression

hydroquinone results in increased expression of SESN2 mRNA

PMID:23416264 PMID:31256213

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

G

sestrin 3

decreases expression

hydroquinone results in decreased expression of SESN3 mRNA

NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842

G

stratifin

affects methylation
increases expression
multiple interactions

hydroquinone affects the methylation of SFN promoter
hydroquinone results in increased expression of SFN mRNA
[hydroquinone affects the methylation of SFN promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of SFN promoter] which results in increased abundance of 5-hydroxymethylcytosine; TET1 protein affects the reaction [hydroquinone results in increased expression of SFN mRNA]

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

secreted frizzled-related protein 1

decreases expression

hydroquinone results in decreased expression of SFRP1 mRNA

NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286

G

surfactant associated 2

increases expression

hydroquinone results in increased expression of SFTA2 mRNA

NCBI chr20:3,093,569...3,094,299
Ensembl chr20:3,093,565...3,094,299

G

sarcoglycan, gamma

increases expression

hydroquinone results in increased expression of SGCG mRNA

NCBI chr15:35,388,836...35,435,072
Ensembl chr15:35,386,534...35,435,148

G

SH3 domain binding glutamate-rich protein

increases expression

hydroquinone results in increased expression of SH3BGR mRNA

NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853

G

SH3-domain binding protein 2

increases expression

hydroquinone results in increased expression of SH3BP2 mRNA

NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251

G

SH3 domain-containing kinase-binding protein 1

increases expression

hydroquinone results in increased expression of SH3KBP1 mRNA

NCBI chr X:34,877,862...35,223,013
Ensembl chr X:34,877,866...35,222,747

G

SH3 domain containing ring finger 2

decreases expression

hydroquinone results in decreased expression of SH3RF2 mRNA

NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856

G

SH3 domain and tetratricopeptide repeats 1

increases expression

hydroquinone results in increased expression of SH3TC1 mRNA

NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995

G

siah E3 ubiquitin protein ligase 1

increases expression

hydroquinone results in increased expression of SIAH1 mRNA

NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808

G

SID1 transmembrane family, member 2

increases expression
multiple interactions

hydroquinone results in increased expression of SIDT2 protein
[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of MIR25]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIDT2 protein promotes the reaction [hydroquinone results in increased expression of NOX4 mRNA]

NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700

G

salt-inducible kinase 1

decreases expression

hydroquinone results in decreased expression of SIK1 mRNA

NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991

G

sirtuin 1

multiple interactions
affects expression
affects response to substance

[SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]
hydroquinone affects the expression of SIRT1 mRNA; hydroquinone affects the expression of SIRT1 protein

PMID:27515134 PMID:28263894

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

sirtuin 3

decreases expression
multiple interactions
increases degradation

hydroquinone results in decreased expression of SIRT3 mRNA; hydroquinone results in decreased expression of SIRT3 protein
[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIRT3 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]

NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808

G

solute carrier family 16, member 6

decreases expression

hydroquinone results in decreased expression of SLC16A6 mRNA

NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779

G

solute carrier family 2 member 1

increases expression

hydroquinone results in increased expression of SLC2A1 protein

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 12

decreases expression

hydroquinone results in decreased expression of SLC2A12 mRNA

NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971

G

solute carrier family 2 member 5

decreases expression

hydroquinone results in decreased expression of SLC2A5 mRNA

NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106

G

solute carrier family 5 member 1

increases expression

hydroquinone results in increased expression of SLC5A1 mRNA

NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547

G

solute carrier family 5 member 3

decreases expression

hydroquinone results in decreased expression of SLC5A3 mRNA

NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883

G

solute carrier family 7 member 11

increases expression

hydroquinone results in increased expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

small integral membrane protein 5

increases expression

hydroquinone results in increased expression of SMIM5 mRNA

NCBI chr10:101,134,033...101,139,814
Ensembl chr10:101,134,033...101,139,813

G

sorting nexin 24

increases expression

hydroquinone results in increased expression of SNX24 mRNA

NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068

G

superoxide dismutase 1

decreases activity
multiple interactions
increases expression
decreases expression

hydroquinone results in decreased activity of SOD1 protein
S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of SOD1 protein]
hydroquinone results in decreased expression of SOD1 mRNA

PMID:15816534 PMID:32141582

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases activity
multiple interactions
increases expression
decreases expression

hydroquinone results in decreased activity of SOD2 protein
S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of SOD2 protein]
hydroquinone results in decreased expression of SOD2 mRNA

PMID:15816534 PMID:32141582

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

SRY-box transcription factor 11

decreases expression

hydroquinone results in decreased expression of SOX11 mRNA

NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354

G

SRY-box transcription factor 2

decreases expression

hydroquinone results in decreased expression of SOX2 mRNA

NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338

G

SRY-box transcription factor 4

decreases expression

hydroquinone results in decreased expression of SOX4 mRNA

NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665

G

Sp1 transcription factor

multiple interactions

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of SP1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

SP110 nuclear body protein

decreases expression

hydroquinone results in decreased expression of SP110 mRNA

NCBI chr 9:86,200,503...86,225,355
Ensembl chr 9:86,200,503...86,222,670

G

Spi-1 proto-oncogene

increases phosphorylation

hydroquinone results in increased phosphorylation of SPI1 protein

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

G

serine peptidase inhibitor, Kazal type 1

increases expression

hydroquinone results in increased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

serine peptidase inhibitor, Kazal type 4

decreases expression

hydroquinone results in decreased expression of SPINK4 mRNA

NCBI chr 5:56,043,936...56,064,841
Ensembl chr 5:55,981,624...56,064,795

G

serine peptidase inhibitor, Kazal type 6

decreases expression

hydroquinone results in decreased expression of SPINK6 mRNA

NCBI chr18:36,397,833...36,410,010
Ensembl chr18:36,397,910...36,409,819

G

small proline rich protein 2B

increases expression

hydroquinone results in increased expression of SPRR2B mRNA

PMID:25240866 PMID:31256213

NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096

G

small proline-rich protein 3

increases expression

hydroquinone results in increased expression of SPRR3 mRNA

PMID:25240866 PMID:31256213

NCBI chr 2:178,027,743...178,028,501
Ensembl chr 2:178,027,425...178,029,891

G

sprouty RTK signaling antagonist 4

increases expression

hydroquinone results in increased expression of SPRY4 mRNA

NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004

G

sequestosome 1

decreases expression
multiple interactions

hydroquinone results in decreased expression of SQSTM1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein]; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein; Chloroquine inhibits the reaction [hydroquinone results in increased degradation of SQSTM1 protein]; hydroquinone results in increased degradation of and results in decreased expression of SQSTM1 protein

PMID:28263894 PMID:35302183 PMID:35561756 PMID:37148176

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

SRC proto-oncogene, non-receptor tyrosine kinase

multiple interactions
increases phosphorylation

AG 1879 inhibits the reaction [hydroquinone results in increased phosphorylation of SRC protein]
hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein]

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 3

decreases expression

hydroquinone results in decreased expression of ST3GAL3 mRNA

NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

decreases expression

hydroquinone results in decreased expression of ST6GALNAC5 mRNA

NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208

G

signal transducer and activator of transcription 1

decreases expression

hydroquinone results in decreased expression of STAT1 mRNA

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

stanniocalcin 2

increases expression

hydroquinone results in increased expression of STC2 mRNA

PMID:23416264 PMID:31256213

NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973

G

serine/threonine kinase 40

increases expression

hydroquinone results in increased expression of STK40 mRNA

NCBI chr 5:138,380,049...138,417,802
Ensembl chr 5:138,381,159...138,417,796

G

syntaxin binding protein 6

decreases expression

hydroquinone results in decreased expression of STXBP6 mRNA

NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024

G

syntabulin

increases expression

hydroquinone results in increased expression of SYBU mRNA

NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828

G

synaptonemal complex protein 2-like

decreases expression

hydroquinone results in decreased expression of SYCP2L mRNA

NCBI chr17:23,589,217...23,645,273
Ensembl chr17:23,592,899...23,648,306

G

TATA-box binding protein associated factor 3

decreases expression

hydroquinone results in decreased expression of TAF3 mRNA

NCBI chr17:68,455,389...68,608,367
Ensembl chr17:68,423,909...68,608,367

G

transaldolase 1

affects expression

hydroquinone affects the expression of TALDO1 protein

NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974