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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:8-Epidiosbulbin E acetate
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Accession:CHEBI:175936 term browser browse the term
Synonyms:exact_synonym: [(1R,2S,3S,5S,8S,10S,11R,13R)-8-(uran-3-yl)-10-methyl-6,15-dioxo-7,14-dioxatetracyclo[11.2.1.02,11.05,10]hexadecan-3-yl] acetate
 related_synonym: Formula=C21H24O7;   InChI=1S/C21H24O7/c1-10(22)26-16-7-15-20(24)28-17(11-3-4-25-9-11)8-21(15,2)14-6-12-5-13(18(14)16)19(23)27-12/h3-4,9,12-18H,5-8H2,1-2H3/t12-,13+,14+,15+,16-,17-,18+,21-/m0/s1;   InChIKey=DYSOIAQEKRDXRB-GFTCARDDSA-N;   SMILES=O1[C@@]2(C[C@]3([C@]4([C@](C[C@H](OC(=O)C)[C@@]3([C@@](C2)(C1=O)[H])[H])(C(O[C@@H](C4)C=5C=COC5)=O)[H])C)[H])[H]
 xref: Chemspider:95532215
 xref_mesh: MESH:C534602


show annotations for term's descendants           Sort by:
8-Epidiosbulbin E acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of ABCB11 protein CTD PMID:31626840 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of ABCC2 mRNA CTD PMID:31626840 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of ABCC3 protein CTD PMID:31626840 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ada adenosine deaminase increases expression ISO 8-epidiosbulbin E acetate results in increased expression of ADA mRNA CTD PMID:31626840 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of BAAT mRNA CTD PMID:31626840 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 8-epidiosbulbin E acetate results in increased expression of CYP1A1 protein CTD PMID:31626840 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of CYP2E1 mRNA CTD PMID:31626840 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases metabolic processing		 ISO Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of 8-epidiosbulbin E acetate] CTD PMID:26286065 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of CYP7A1 mRNA; 8-epidiosbulbin E acetate results in decreased expression of CYP7A1 protein CTD PMID:31626840 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of CYP8B1 protein CTD PMID:31626840 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Fh fumarate hydratase decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of FH1 mRNA CTD PMID:31626840 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity ISO 8-epidiosbulbin E acetate results in increased activity of GPT protein CTD PMID:31626840 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of IDH2 mRNA CTD PMID:31626840 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of SLC10A1 protein CTD PMID:31626840 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of SLCO1A4 mRNA CTD PMID:31626840 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of UGT1A1 mRNA CTD PMID:31626840 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      atom 19892
        nonmetal atom 19849
          oxygen atom 19587
            oxygen molecular entity 19587
              organooxygen compound 19205
                8-Epidiosbulbin E acetate 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            organic molecule 19755
                              organic cyclic compound 19545
                                organic heterocyclic compound 18906
                                  organic heteropolycyclic compound 18314
                                    organic heterotricyclic compound 15658
                                      8-Epidiosbulbin E acetate 16
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