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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-carotene
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Accession:CHEBI:17579 term browser browse the term
Definition:A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid.
Synonyms:exact_synonym: beta,beta-carotene
 related_synonym: 1,1'-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl]bis(2,6,6-trimethylcyclohexene);   Formula=C40H56;   InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+;   InChIKey=OENHQHLEOONYIE-JLTXGRSLSA-N;   SMILES=CC(\\C=C\\C=C(C)\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C;   all-trans-beta-carotene;   beta-Karotin
 alt_id: CHEBI:10355;   CHEBI:12392;   CHEBI:22834;   CHEBI:40987
 xref: CAS:7235-40-7;   COMe:MOL000093;   Drug_Central:345;   HMDB:HMDB0000561;   KEGG:C02094;   KEGG:D03101;   KNApSAcK:C00000919;   LIPID_MAPS_instance:LMPR01070000;   LIPID_MAPS_instance:LMPR01070001
 xref_mesh: MESH:D019207
 xref: MetaCyc:CPD1F-129;   PDBeChem:BCR;   PMID:11171227;   PMID:11182771;   PMID:11332447;   PMID:11359610;   PMID:11382814;   PMID:11567548;   PMID:11677037;   PMID:11714348;   PMID:11962062;   PMID:12081834;   PMID:12891827;   PMID:14658721;   PMID:14764912;   PMID:14976384;   PMID:14997360;   PMID:15113067;   PMID:15333155;   PMID:15695449;   PMID:15789045;   PMID:15909543;   PMID:15949680;   PMID:15949683;   PMID:16036331;   PMID:16087476;   PMID:16338959;   PMID:16563447;   PMID:17004738;   PMID:17625873;   PMID:17708644;   PMID:17851775;   PMID:18429004;   PMID:18766464;   PMID:18767554;   PMID:18794175;   PMID:19480350;   PMID:19574250;   PMID:19669835;   PMID:19703237;   PMID:19852884;   PMID:19888275;   PMID:19896667;   PMID:19937581;   PMID:20074992;   PMID:20515074;   PMID:22079732;   PMID:22309480;   PMID:22428124;   PMID:22489215;   PMID:22534340;   PMID:22575730;   Reaxys:1917416;   Wikipedia:Beta_Carotene



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beta-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acad9 acyl-CoA dehydrogenase family, member 9 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA CTD PMID:24657404 NCBI chr 2:120,871,329...120,894,306
Ensembl chr 2:120,871,227...120,894,709
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO beta Carotene results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO beta Carotene results in decreased expression of ADIPOQ mRNA CTD PMID:21569430 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA CTD PMID:24657404 NCBI chr14:84,951,577...84,962,840
Ensembl chr14:84,952,822...84,962,843
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
decreases expression
ISO beta Carotene results in decreased phosphorylation of AKT1 protein
beta Carotene results in decreased expression of AKT1 mRNA
CTD PMID:26733226 PMID:36819991 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased expression of ALAD protein] CTD PMID:25542264 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression ISO beta Carotene results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO beta Carotene results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:157,162,945...157,188,673
JBrowse link
G Ank2 ankyrin 2 increases expression ISO beta Carotene results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259
JBrowse link
G Ank3 ankyrin 3 increases expression ISO beta Carotene results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA CTD PMID:24657404 NCBI chr10:70,555,212...70,597,267
Ensembl chr10:70,555,212...70,597,193
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA CTD PMID:24657404 NCBI chr18:30,702,602...31,489,047
Ensembl chr18:31,089,787...31,489,047
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO beta Carotene results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr16:57,669,927...57,701,349
Ensembl chr16:57,669,750...57,718,305
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 increases expression ISO beta Carotene results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 9:99,566,852...99,588,321
Ensembl chr 9:99,567,867...99,583,907
JBrowse link
G Asb9 ankyrin repeat and SOCS box-containing 9 increases expression ISO beta Carotene results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:33,588,484...33,633,285
Ensembl chr  X:33,588,484...33,624,397
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA CTD PMID:24657404 NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027
JBrowse link
G Bag3 BAG cochaperone 3 decreases expression ISO beta Carotene results in decreased expression of BAG3 mRNA CTD PMID:17034753 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
JBrowse link
G Bag4 BAG cochaperone 4 decreases expression ISO beta Carotene results in decreased expression of BAG4 mRNA CTD PMID:17034753 NCBI chr16:72,991,407...73,008,620
Ensembl chr16:72,991,362...73,013,273
JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO beta Carotene results in decreased expression of BAG5 mRNA CTD PMID:17034753 NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:136,584,741...136,598,492
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO beta Carotene results in decreased expression of BAX mRNA
beta Carotene results in increased expression of BAX mRNA; beta Carotene results in increased expression of BAX protein
CTD PMID:15949688 PMID:17034753 PMID:26733226 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO beta Carotene results in decreased expression of BCL2 protein CTD PMID:26733226 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions
affects response to substance
increases oxidation
increases expression
ISO
EXP
beta Carotene results in increased expression of and results in increased activity of BCO1 protein
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA
BCO1 protein results in increased oxidation of beta Carotene
beta Carotene results in increased expression of BCO1 mRNA
Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]; Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]; Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]
CTD PMID:9526112 PMID:16186334 PMID:24657404 NCBI chr19:62,058,061...62,094,923
Ensembl chr19:62,058,089...62,094,917
JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions
increases metabolic processing
ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal CTD PMID:21106934 NCBI chr 8:59,778,571...59,803,597
Ensembl chr 8:59,778,575...59,799,168
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]
beta Carotene metabolite results in increased activity of CASP3 protein; beta Carotene results in increased activity of CASP3 protein
CTD PMID:17618090 PMID:26733226 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions EXP
ISO
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; beta Carotene inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; beta Carotene inhibits the reaction [Indomethacin results in decreased expression of CAT protein]
beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of CAT protein]
CTD PMID:9306888 PMID:12500499 PMID:25542264 PMID:31022331 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cav1 caveolin 1 decreases expression ISO beta Carotene results in decreased expression of CAV1 protein CTD PMID:26733226 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO beta Carotene results in decreased expression of CCND1 protein CTD PMID:26733226 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cdca8 cell division cycle associated 8 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA CTD PMID:24657404 NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283
JBrowse link
G Cdh1 cadherin 1 increases expression ISO beta Carotene results in increased expression of CDH1 mRNA; beta Carotene results in increased expression of CDH1 protein CTD PMID:17034753 PMID:26733226 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO beta Carotene results in decreased expression of CEBPA mRNA CTD PMID:21569430 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
JBrowse link
G Cenpe centromere protein E multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA CTD PMID:24657404 NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beta Carotene results in increased expression of CFLAR mRNA CTD PMID:17034753 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA CTD PMID:24657404 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984
JBrowse link
G Cldn10 claudin 10 increases expression ISO beta Carotene results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr15:102,269,858...102,361,589
Ensembl chr15:102,269,858...102,361,589
JBrowse link
G Cldn18 claudin 18 increases expression ISO beta Carotene results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 8:109,125,819...109,145,110
Ensembl chr 8:109,126,949...109,152,701
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO beta Carotene results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO beta Carotene results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression ISO beta Carotene results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520
JBrowse link
G Coq7 coenzyme Q7, hydroxylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA CTD PMID:24657404 NCBI chr 1:182,270,570...182,285,959
Ensembl chr 1:182,269,399...182,285,508
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO beta Carotene results in decreased expression of CPT1B mRNA CTD PMID:21569430 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain increases expression ISO beta Carotene results in increased expression of CRADD mRNA CTD PMID:17034753 NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:31,685,622...31,874,512
JBrowse link
G Ctnnal1 catenin alpha-like 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA CTD PMID:24657404 NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637
JBrowse link
G Ctsb cathepsin B decreases expression ISO beta Carotene results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO beta Carotene results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO beta Carotene results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO beta Carotene results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO beta Carotene results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]] CTD PMID:16970932 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO beta Carotene results in increased expression of CYP26A1 mRNA CTD PMID:16186334 PMID:22542753 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression ISO beta Carotene results in increased expression of CYP3A43 mRNA CTD PMID:17034753 NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA CTD PMID:24657404 NCBI chr 2:25,320,895...25,346,004 JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO beta Carotene results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255
JBrowse link
G Dlx4 distal-less homeobox 4 increases expression ISO beta Carotene results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr10:80,581,878...80,587,272
Ensembl chr10:80,582,303...80,587,294
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO [Xiao-Ke-An results in increased abundance of beta Carotene] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Dtwd2 DTW domain containing 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA CTD PMID:24657404 NCBI chr18:45,003,242...45,088,595
Ensembl chr18:45,003,644...45,088,419
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA CTD PMID:24657404 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA CTD PMID:24657404 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO beta Carotene results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:17051425 PMID:19340624 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO beta Carotene results in decreased expression of FABP4 mRNA CTD PMID:21569430 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beta Carotene results in increased expression of FAIM2 mRNA CTD PMID:17034753 NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO beta Carotene results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
JBrowse link
G Foxa1 forkhead box A1 increases expression ISO beta Carotene results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
JBrowse link
G Foxm1 forkhead box M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA CTD PMID:24657404 NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
JBrowse link
G Fzd6 frizzled class receptor 6 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA CTD PMID:24657404 NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO beta Carotene results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO beta Carotene results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
ISO
EXP
beta Carotene promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]; Ro 41-5253 inhibits the reaction [beta Carotene results in increased expression of GJA1 protein]
beta Carotene inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein]
CTD PMID:16091010 PMID:27154496 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein] CTD PMID:25542264 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO beta Carotene results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO beta Carotene results in increased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression ISO beta Carotene results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638
JBrowse link
G Gstm5l glutathione S-transferase, mu 5-like increases expression ISO beta Carotene results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 2:198,231,285...198,238,122
Ensembl chr 2:198,232,596...198,238,252
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO beta Carotene results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233
JBrowse link
G Hoxa7 homeobox A7 increases expression ISO beta Carotene results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:82,646,364...82,648,241
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO beta Carotene results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr10:81,755,263...81,763,999 JBrowse link
G Hoxc10 homeo box C10 increases expression ISO beta Carotene results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr 7:135,982,222...135,987,442
Ensembl chr 7:135,982,065...135,986,712
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions EXP beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]] CTD PMID:21447443 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Irf8 interferon regulatory factor 8 increases expression ISO beta Carotene results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression
multiple interactions
ISO beta Carotene results in decreased expression of IRX4 mRNA
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA
CTD PMID:17034753 PMID:24657404 NCBI chr 1:31,859,101...31,868,089
Ensembl chr 1:31,859,101...31,868,089
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO beta Carotene results in decreased expression of ITGB1 mRNA CTD PMID:17034753 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO beta Carotene results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932
JBrowse link
G Itm2a integral membrane protein 2A multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA CTD PMID:24657404 NCBI chr  X:76,559,183...76,565,144
Ensembl chr  X:76,559,181...76,565,437
JBrowse link
G Ivl involucrin increases expression ISO beta Carotene results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA CTD PMID:24657404 NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
JBrowse link
G Krt18 keratin 18 increases expression ISO beta Carotene results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848
JBrowse link
G Krt19 keratin 19 increases expression ISO beta Carotene results in increased expression of KRT19 mRNA CTD PMID:17034753 NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952
JBrowse link
G Krt2 keratin 2 increases expression ISO beta Carotene results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr 7:134,819,584...134,826,736
Ensembl chr 7:134,819,584...134,827,011
JBrowse link
G Krt7 keratin 7 affects expression ISO beta Carotene affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786
JBrowse link
G Krt8 keratin 8 decreases expression ISO beta Carotene results in decreased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
JBrowse link
G Lancl1 LanC like glutathione S-transferase 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA CTD PMID:24657404 NCBI chr 9:75,968,284...75,998,397
Ensembl chr 9:75,968,286...76,003,475
JBrowse link
G Lhx3 LIM homeobox 3 increases expression ISO beta Carotene results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:29,424,620...29,432,637
JBrowse link
G Lmnb2 lamin B2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA CTD PMID:24657404 NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:9,440,128...9,459,342
JBrowse link
G LOC100912356 interferon alpha-1-like increases expression ISO beta Carotene results in increased expression of IFNA5 mRNA CTD PMID:17034753 NCBI chr 5:108,343,570...108,346,248 JBrowse link
G Lpl lipoprotein lipase decreases expression ISO beta Carotene results in decreased expression of LPL mRNA CTD PMID:21569430 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
beta Carotene results in increased phosphorylation of MAPK1 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
beta Carotene results in increased phosphorylation of MAPK3 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mbl2 mannose binding lectin 2 multiple interactions ISO MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] CTD PMID:16960176 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO beta Carotene affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO beta Carotene results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:123,197,066...123,399,002
Ensembl chr 3:123,197,066...123,397,751
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO beta Carotene results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976
JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA CTD PMID:24657404 NCBI chr 9:73,400,223...73,484,677
Ensembl chr 9:73,471,813...73,481,339
JBrowse link
G Mettl9 methyltransferase 9, His-X-His N1(pi)-histidine multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA CTD PMID:24657404 NCBI chr 1:185,006,953...185,054,359
Ensembl chr 1:185,006,954...185,054,861
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase affects response to substance ISO MGMT gene SNP affects the susceptibility to beta Carotene CTD PMID:16014702 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 increases expression ISO beta Carotene results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 4:6,541,645...6,546,604
Ensembl chr 4:6,541,645...6,546,604
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA CTD PMID:24657404 NCBI chr15:36,086,457...36,087,319
Ensembl chr15:36,086,457...36,087,298
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO beta Carotene results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr20:3,779,180...3,797,996
Ensembl chr20:3,781,578...3,797,994
JBrowse link
G Mtch2 mitochondrial carrier 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA CTD PMID:24657404 NCBI chr 3:97,286,388...97,306,028
Ensembl chr 3:97,285,894...97,307,327
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO beta Carotene results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
JBrowse link
G Nckap1 NCK-associated protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA CTD PMID:24657404 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797
JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA CTD PMID:24657404 NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO beta Carotene results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA] CTD PMID:18779489 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
beta Carotene results in increased activity of NR1I2 protein
CTD PMID:15949683 PMID:16632523 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO beta Carotene results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA CTD PMID:24657404 NCBI chr19:50,499,420...50,502,301
Ensembl chr19:50,499,442...50,502,674
JBrowse link
G Pcdh1 protocadherin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA CTD PMID:24657404 NCBI chr18:30,258,154...30,290,828
Ensembl chr18:30,258,154...30,290,436
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 increases expression ISO beta Carotene results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr18:29,884,245...29,919,095 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO beta Carotene results in increased expression of PIK3R5 protein CTD PMID:20025956 NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA CTD PMID:24657404 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO beta Carotene results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:101,664,056...101,684,614
JBrowse link
G Plscr3 phospholipid scramblase 3 increases expression ISO beta Carotene results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr10:55,064,349...55,070,120
Ensembl chr10:55,065,345...55,070,369
JBrowse link
G Plscr4 phospholipid scramblase 4 increases expression ISO beta Carotene results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 8:101,867,057...101,905,827
Ensembl chr 8:101,866,888...101,905,831
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO beta Carotene results in decreased expression of PPARA mRNA CTD PMID:21569430 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO beta Carotene results in decreased expression of PPARG mRNA CTD PMID:21569430 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO beta Carotene results in decreased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680
JBrowse link
G Rad51d RAD51 paralog D increases expression ISO beta Carotene results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr10:68,303,350...68,322,002
Ensembl chr10:68,238,273...68,321,902
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO beta Carotene results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO beta Carotene results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO beta Carotene results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024
JBrowse link
G Rbp4 retinol binding protein 4 multiple interactions ISO beta Carotene results in decreased expression of and results in decreased secretion of RBP4 protein CTD PMID:22542753 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases phosphorylation ISO beta Carotene results in decreased phosphorylation of RELA protein CTD PMID:26733226 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA CTD PMID:24657404 NCBI chr15:19,268,025...19,278,216
Ensembl chr15:19,266,834...19,282,122
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA CTD PMID:24657404 NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:166,235,900...166,260,944
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases transport ISO SCARB1 protein results in increased transport of beta Carotene CTD PMID:16177187 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980
JBrowse link
G Six6 SIX homeobox 6 increases expression ISO beta Carotene results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr 6:97,357,883...97,375,415
Ensembl chr 6:97,370,435...97,375,415
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO beta Carotene results in decreased expression of SLC2A4 mRNA CTD PMID:21569430 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO beta Carotene results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CTD PMID:18779489 PMID:23859036 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 affects expression ISO beta Carotene affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:112,679,623...112,762,640
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO beta Carotene results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Tfcp2 transcription factor CP2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA CTD PMID:24657404 NCBI chr 7:133,495,577...133,537,799
Ensembl chr 7:133,495,577...133,537,531
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO beta Carotene results in increased expression of TGM2 mRNA CTD PMID:17034753 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
JBrowse link
G Tgm4 transglutaminase 4 increases expression ISO beta Carotene results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 8:131,566,887...131,603,920
Ensembl chr 8:131,566,887...131,603,920
JBrowse link
G Thoc7 THO complex subunit 7 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA CTD PMID:24657404 NCBI chr15:13,692,855...13,707,692
Ensembl chr15:13,693,396...13,707,704
JBrowse link
G Tmem209 transmembrane protein 209 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA CTD PMID:24657404 NCBI chr 4:60,070,346...60,096,039
Ensembl chr 4:60,069,060...60,105,946
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]
beta Carotene promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:19135038 PMID:21447443 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO beta Carotene results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:166,664,494...166,690,831
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO beta Carotene results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA CTD PMID:24657404 NCBI chr 3:71,269,425...71,343,936
Ensembl chr 3:71,269,425...71,343,936
JBrowse link
G Twf1 twinfilin actin-binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA CTD PMID:24657404 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:127,595,210...127,607,105
JBrowse link
G Txndc9 thioredoxin domain containing 9 increases expression ISO beta Carotene results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 9:47,707,628...47,717,761
Ensembl chr 9:47,707,231...47,880,085
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA CTD PMID:24657404 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO beta Carotene results in decreased expression of VEGFA mRNA CTD PMID:36819991 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO beta Carotene results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822
JBrowse link
G Ythdc2 YTH N6-methyladenosine RNA binding protein C2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA CTD PMID:24657404 NCBI chr18:37,517,286...37,582,551
Ensembl chr18:37,517,248...37,582,550
JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA CTD PMID:24657404 NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:131,602,663...131,650,998
JBrowse link
astaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA] CTD PMID:16964424 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased phosphorylation of AKT1 protein] CTD PMID:33008094 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alb albumin multiple interactions EXP astaxanthine inhibits the reaction [thiacloprid results in decreased expression of ALB protein] CTD PMID:34564187 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA] CTD PMID:16964424 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Arg1 arginase 1 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of ARG1 mRNA] CTD PMID:33008094 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA] CTD PMID:34439521 NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
JBrowse link
G Atg14 autophagy related 14 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG14 mRNA] CTD PMID:34439521 NCBI chr15:23,275,457...23,306,817
Ensembl chr15:23,275,457...23,306,815
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] CTD PMID:33212048 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein] CTD PMID:39873358 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Becn1 beclin 1 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased expression of BECN1 mRNA]; astaxanthine inhibits the reaction [bisphenol A results in increased expression of BECN1 protein] CTD PMID:34439521 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
JBrowse link
G C1qa complement C1q A chain decreases expression ISO astaxanthine results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein]
CTD PMID:33212048 PMID:39873358 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions ISO
EXP
astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA]
astaxanthine inhibits the reaction [thiacloprid results in decreased activity of CAT protein]
CTD PMID:16964424 PMID:34564187 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cntd1 cyclin N-terminal domain containing 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA] CTD PMID:16964424 NCBI chr10:86,721,692...86,732,074 JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP astaxanthine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein] CTD PMID:36084724 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA] CTD PMID:16964424 NCBI chr 1:252,554,811...252,571,471
Ensembl chr 1:252,554,811...252,571,471
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA] CTD PMID:16964424 NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA] CTD PMID:16964424 NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA] CTD PMID:16964424 NCBI chr 1:95,002,513...95,011,516
Ensembl chr 1:95,001,707...95,011,431
Ensembl chr 5:95,001,707...95,011,431
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA] CTD PMID:16964424 NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:69,014,417...69,027,166
JBrowse link
G Ctss cathepsin S decreases expression ISO astaxanthine results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
EXP astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]]
astaxanthine results in decreased expression of CYBB mRNA
CTD PMID:23272707 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP astaxanthine results in increased expression of and results in increased activity of CYP1A1 protein
astaxanthine results in increased expression of CYP1A1 mRNA
CTD PMID:21414371 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA] CTD PMID:16964424 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
multiple interactions
EXP astaxanthine results in increased activity of G6PD protein
[Cadmium co-treated with astaxanthine] results in decreased activity of G6PD protein
CTD PMID:28665548 PMID:29975440 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO astaxanthine results in decreased expression of GFAP mRNA CTD PMID:19555370 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
ISO astaxanthine results in increased expression of GJA1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [astaxanthine results in increased expression of GJA1 protein]; astaxanthine promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]
CTD PMID:16091010 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gna13 G protein subunit alpha 13 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA] CTD PMID:16964424 NCBI chr10:94,837,271...94,870,290
Ensembl chr10:94,836,444...94,874,968
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP astaxanthine inhibits the reaction [thiacloprid results in increased expression of GPT protein] CTD PMID:34564187 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA] CTD PMID:16964424 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions
increases expression
EXP
ISO
astaxanthine inhibits the reaction [IL1B protein results in decreased expression of GPX4 protein]
astaxanthine inhibits the reaction [erastin results in decreased expression of GPX4 protein]
astaxanthine results in increased expression of GPX4 protein
CTD PMID:36084724 PMID:37648051 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]] CTD PMID:23538867 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754
JBrowse link
G Grn granulin precursor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA] CTD PMID:16964424 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP astaxanthine inhibits the reaction [Cadmium results in decreased activity of GSR protein] CTD PMID:29975440 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
increases expression
ISO [astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of GSTM2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of GSTM2 mRNA
astaxanthine results in increased expression of GSTM2 mRNA
CTD PMID:24157545 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA]
astaxanthine inhibits the reaction [thiacloprid results in increased expression of HMGB1 mRNA]
CTD PMID:16964424 PMID:34564187 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
EXP
ISO
astaxanthine results in increased expression of HMOX1 protein
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of HMOX1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of HMOX1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]
astaxanthine results in increased expression of HMOX1 mRNA
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]]
astaxanthine results in decreased expression of HMOX1 mRNA
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 protein]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33008094 PMID:33212048 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hoxa9 homeobox A9 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA] CTD PMID:16964424 NCBI chr 4:82,653,847...82,659,958
Ensembl chr 4:82,653,825...82,662,093
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA] CTD PMID:16964424 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
JBrowse link
G Ifng interferon gamma increases expression ISO astaxanthine results in increased expression of IFNG protein CTD PMID:33132140 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of IL10 mRNA]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]; astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL10 protein]
CTD PMID:33008094 PMID:34564187 PMID:39873358 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il11 interleukin 11 increases expression ISO astaxanthine results in increased expression of IL11 protein CTD PMID:33132140 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of IL1B mRNA; astaxanthine results in decreased expression of IL1B protein
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of IL1B mRNA]
[astaxanthine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B protein; astaxanthine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]; astaxanthine inhibits the reaction [IL1B protein results in decreased expression of GPX4 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of P53 protein]; astaxanthine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL1B protein]
CTD PMID:21621527 PMID:33008094 PMID:34564187 PMID:36084724 PMID:39873358 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of IL6 mRNA
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of IL6 mRNA]
[astaxanthine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL6 protein
CTD PMID:21621527 PMID:33008094 PMID:39873358 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 decreases expression ISO astaxanthine results in decreased expression of INS1 protein CTD PMID:33132140 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Lepr leptin receptor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein] CTD PMID:34439521 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein] CTD PMID:34439521 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased phosphorylation of MAPK8 protein] CTD PMID:33008094 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP astaxanthine inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] CTD PMID:36084724 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA] CTD PMID:16964424 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA] CTD PMID:16964424 NCBI chr  X:121,289,904...121,293,555
Ensembl chr  X:121,289,925...121,293,555
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA] CTD PMID:16964424 NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA] CTD PMID:16964424 NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA] CTD PMID:16964424 NCBI chr 9:113,137,305...113,157,571
Ensembl chr 9:113,137,306...113,157,520
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP
ISO
astaxanthine results in increased expression of NFE2L2 protein
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NFE2L2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NFE2L2 mRNA; astaxanthine promotes the reaction [Hydrogen Peroxide results in increased expression of NFE2L2 mRNA]
astaxanthine results in increased expression of NFE2L2 mRNA
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]]
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which affects the localization of NFE2L2 protein]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33008094 PMID:33212048 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA] CTD PMID:16964424 NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NOS2 mRNA]; astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NOS2 protein]
astaxanthine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; astaxanthine inhibits the reaction [thiacloprid results in increased expression of NOS2 mRNA]
CTD PMID:33008094 PMID:34564187 PMID:36084724 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
EXP
ISO
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein
astaxanthine results in increased expression of NQO1 protein
astaxanthine results in increased expression of NQO1 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NQO1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NQO1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of NQO1 mRNA]
CTD PMID:20038455 PMID:24157545 PMID:33212048 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions EXP astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of P2RX7 protein] CTD PMID:39873358 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO astaxanthine results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627
JBrowse link
G Pgd phosphogluconate dehydrogenase increases activity EXP astaxanthine results in increased activity of PGD protein CTD PMID:28665548 PMID:29975440 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
JBrowse link
G Por cytochrome p450 oxidoreductase decreases activity
increases expression
EXP astaxanthine results in decreased activity of POR protein
astaxanthine results in increased expression of POR protein
CTD PMID:21414371 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA] CTD PMID:16964424 NCBI chr 6:29,681,099...29,712,835
Ensembl chr 6:29,681,100...29,712,924
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA] CTD PMID:16964424 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of PTEN mRNA] CTD PMID:33212048 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of PTGS2 mRNA
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PTGS2 mRNA]
astaxanthine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD PMID:21621527 PMID:33008094 PMID:36084724 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of RELA protein]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein]
CTD PMID:34439521 PMID:39873358 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rps2 ribosomal protein S2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA] CTD PMID:16964424 NCBI chr10:14,251,841...14,253,697
Ensembl chr10:14,251,380...14,253,695
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO astaxanthine results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:82,281,221...82,431,664
Ensembl chr 4:82,263,709...82,432,886
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA] CTD PMID:16964424 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions EXP [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of and affects the localization of SP1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]] CTD PMID:23538867 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA] CTD PMID:16964424 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA] CTD PMID:16964424 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
JBrowse link
G Tkt transketolase multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA] CTD PMID:16964424 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TLR2 mRNA] CTD PMID:33008094 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TLR4 mRNA] CTD PMID:33008094 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
multiple interactions
ISO
EXP
astaxanthine results in decreased expression of TNF protein
astaxanthine results in increased expression of TNF protein
astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TNF mRNA]
astaxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]
CTD PMID:21621527 PMID:33008094 PMID:33132140 PMID:39873358 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein] CTD PMID:20038455 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 multiple interactions ISO astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TREM2 mRNA] CTD PMID:33008094 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779
JBrowse link
G Ubb ubiquitin B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA] CTD PMID:16964424 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,727,701...47,750,335
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA] CTD PMID:16964424 NCBI chr 7:65,700,016...65,705,382
Ensembl chr 7:65,700,029...65,705,558
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 1:184,599,240...184,629,804
Ensembl chr 1:184,599,212...184,630,946
JBrowse link
canthaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO
EXP
Canthaxanthin results in increased expression of CYP1A1 mRNA CTD PMID:9271336 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP
ISO
Canthaxanthin results in increased expression of CYP1A2 mRNA CTD PMID:9271336 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20873
    role 20805
      chemical role 20383
        antioxidant 16456
          beta-carotene 234
            4,4-dihydroxy-all-trans-beta-carotene 0
            4-hydroxy-all-trans-beta-carotene 0
            7,8-dihydro-beta-carotene 0
            astacene 0
            astaxanthin + 83
            beta-carotene 5,6-epoxide + 0
            beta-cryptoxanthin + 0
            canthaxanthin 2
            echinenone + 0
            meso-zeaxanthin 0
            zeaxanthin + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20873
    subatomic particle 20871
      composite particle 20871
        hadron 20871
          baryon 20871
            nucleon 20871
              atomic nucleus 20871
                atom 20871
                  main group element atom 20794
                    main group molecular entity 20794
                      s-block molecular entity 20589
                        hydrogen molecular entity 20573
                          hydrides 19703
                            organic hydride 19082
                              organic fundamental parent 19082
                                hydrocarbon 18736
                                  terpene 14160
                                    tetraterpene 668
                                      carotene 668
                                        carotenoid 668
                                          carotenoid beta-end derivative 276
                                            beta-carotene 234
                                              4,4-dihydroxy-all-trans-beta-carotene 0
                                              4-hydroxy-all-trans-beta-carotene 0
                                              7,8-dihydro-beta-carotene 0
                                              astacene 0
                                              astaxanthin + 83
                                              beta-carotene 5,6-epoxide + 0
                                              beta-cryptoxanthin + 0
                                              canthaxanthin 2
                                              echinenone + 0
                                              meso-zeaxanthin 0
                                              zeaxanthin + 0
paths to the root