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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alginic acid
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Accession:CHEBI:17548 term browser browse the term
Definition:A linear copolymer macromolecule composed of homopolymeric blocks of 1->4-linked beta-D-mannuronic acid and alpha-L-guluronic acid residues, covalently linked together in different sequences or blocks.
Synonyms:related_synonym: (Alginate)n+1;   (alginate)n;   Alginate;   Formula=(C12H16O13)n;   Formula=(C6H8O6)n.H2O;   Norgine
 alt_id: CHEBI:11097;   CHEBI:18823;   CHEBI:22308;   CHEBI:271
 xref: Beilstein:8192143;   CAS:9005-32-7;   KEGG:C01768;   KEGG:D02324;   KEGG:G10593
 xref_mesh: MESH:C008970
 xref: PMID:25449544;   Wikipedia:Alginic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:58187


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alginic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan increases expression ISO alginic acid results in increased expression of ACAN mRNA CTD PMID:16371897 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO Alginic Acid results in increased expression of ATG12 protein CTD PMID:35066102 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg7 autophagy related 7 increases expression ISO Alginic Acid results in increased expression of ATG7 protein CTD PMID:35066102 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Alginic Acid results in decreased expression of BCL2 protein CTD PMID:35066102 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Alginic Acid results in decreased expression of BCL2L1 protein CTD PMID:35066102 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Becn1 beclin 1 increases expression ISO Alginic Acid results in increased expression of BECN1 protein CTD PMID:35066102 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage		 ISO Alginic Acid results in increased expression of CASP3 protein
Alginic Acid results in increased cleavage of CASP3 protein		 CTD PMID:35066102 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO Alginic Acid results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:35066102 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression ISO Alginic Acid results in increased expression of CASP9 protein CTD PMID:35066102 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases expression ISO Alginic Acid results in decreased expression of CAT protein CTD PMID:35066102 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression ISO alginic acid results in increased expression of COL10A1 mRNA CTD PMID:16371897 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO Alginic Acid results in increased expression of CYP17A1 protein CTD PMID:35066102 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO Alginic Acid results in decreased expression of CYP19A1 protein CTD PMID:35066102 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO Alginic Acid results in decreased expression of FSHR protein CTD PMID:35066102 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Gpx5 glutathione peroxidase 5 decreases expression ISO Alginic Acid results in decreased expression of GPX5 protein CTD PMID:35066102 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation ISO Alginic Acid results in increased lipidation of MAP1LC3B protein CTD PMID:35066102 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Alginic Acid results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:35066102 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family increases expression ISO Alginic Acid results in increased expression of RAB7 protein CTD PMID:35066102 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO Alginic Acid results in decreased expression of SOD1 protein CTD PMID:35066102 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Alginic Acid results in decreased expression of SOD2 protein CTD PMID:35066102 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO Alginic Acid results in decreased expression of SQSTM1 protein CTD PMID:35066102 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Alginic Acid results in decreased expression of STAR protein CTD PMID:35066102 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alginic acid inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; alginic acid inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        pharmaceutical 19556
          drug 19556
            hematologic agent 4990
              alginic acid 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbohydrates and carbohydrate derivatives 15275
                                    carbohydrate 15302
                                      polysaccharide 8219
                                        heteroglycan 24
                                          alginic acid 24
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