CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Oleacein
Accession: CHEBI:175090
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Synonyms: exact_synonym: 2-(3,4-dihydroxyphenyl)ethyl (Z)-4-ormyl-3-(2-oxoethyl)hex-4-enoate
related_synonym: Formula=C17H20O6; InChI=1S/C17H20O6/c1-2-13(11-19)14(5-7-18)10-17(22)23-8-6-12-3-4-15(20)16(21)9-12/h2-4,7,9,11,14,20-21H,5-6,8,10H2,1H3/b13-2+; InChIKey=XLPXUPOZUYGVPD-XNJYKOPJSA-N; SMILES=O(C(=O)CC(CC=O)/C(=C/C)/C=O)CCC1=CC(O)=C(O)C=C1
xref: Chemspider:18953409; HMDB:HMDB0037321
xref_mesh: MESH:C578055
G
Acly
ATP citrate lyase
decreases activity
ISO
oleacein results in decreased activity of ACLY protein
CTD
PMID:31150784
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
G
Comt
catechol-O-methyltransferase
decreases activity
ISO
oleacein results in decreased activity of COMT protein
CTD
PMID:30935952
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
G
Dot1l
DOT1 like histone lysine methyltransferase
decreases activity
ISO
oleacein results in decreased activity of DOT1L protein
CTD
PMID:31150784
NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475
G
Itgam
integrin subunit alpha M
multiple interactions
ISO
Oleacein inhibits the reaction [lipopolysaccharide increases expression of ITGAM protein on neutrophils]
RGD
PMID:24491692
RGD:329853765
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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