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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4',5,7-Trimethoxyflavone
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Accession:CHEBI:174981 term browser browse the term
Synonyms:exact_synonym: 5,7-dimethoxy-2-(4-methoxyphenyl)chromen-4-one
 related_synonym: Formula=C18H16O5;   InChI=1S/C18H16O5/c1-20-12-6-4-11(5-7-12)15-10-14(19)18-16(22-3)8-13(21-2)9-17(18)23-15/h4-10H,1-3H3;   InChIKey=ZXJJBDHPUHUUHD-UHFFFAOYSA-N;   SMILES=O1C2=C(C(OC)=CC(OC)=C2)C(=O)C=C1C3=CC=C(OC)C=C3
 xref: CAS:5631-70-9;   Chemspider:72029;   HMDB:HMDB0030842;   KEGG:C14985;   LIPID_MAPS_instance:LMPK12111071
 xref_mesh: MESH:C103112



show annotations for term's descendants           Sort by:
4',5,7-Trimethoxyflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 5,7,4'-trimethylapigenin inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein] CTD PMID:24134915 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO 5,7,4'-trimethylapigenin results in decreased expression of CYP1B1 mRNA CTD PMID:17637178 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 5,7,4'-trimethylapigenin inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; 5,7,4'-trimethylapigenin inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] CTD PMID:24134915 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 5,7,4'-trimethylapigenin inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] CTD PMID:24134915 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    chemical entity 19915
      atom 19915
        nonmetal atom 19838
          carbon atom 19790
            organic molecular entity 19790
              flavonoids 11629
                4',5,7-Trimethoxyflavone 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19794
                        carbon atom 19790
                          organic molecular entity 19790
                            heteroorganic entity 19548
                              organochalcogen compound 19307
                                organooxygen compound 19223
                                  ether 17323
                                    4',5,7-Trimethoxyflavone 4
paths to the root