Licochalcone B - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	Licochalcone B	go back to main search page
Accession:	CHEBI:174733	browse the term
Synonyms:	exact_synonym:	(E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
	related_synonym:	Formula=C16H14O5; InChI=1S/C16H14O5/c1-21-16-11(5-9-14(19)15(16)20)4-8-13(18)10-2-6-12(17)7-3-10/h2-9,17,19-20H,1H3/b8-4+; InChIKey=DRDRYGIIYOPBBZ-XBXARRHUSA-N; SMILES=O(C1=C(C=CC(O)=C1O)/C=C/C(=O)C2=CC=C(O)C=C2)C
	xref:	CAS:58749-23-8; Chemspider:4477423; HMDB:HMDB0037320; LIPID_MAPS_instance:LMPK12120434
	xref_mesh:	MESH:C541528

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Genes (758)

Licochalcone B

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

decreases expression

licochalcone B results in decreased expression of ABCA1 mRNA

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 8

decreases expression

licochalcone B results in decreased expression of ABCA8 mRNA

NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988

G

ATP-binding cassette, subfamily A (ABC1), member 8a

increases expression

licochalcone B results in increased expression of ABCA10 mRNA

NCBI chr10:95,002,334...95,072,315
Ensembl chr10:95,002,334...95,072,375

G

ATP binding cassette subfamily B member 4

increases expression

licochalcone B results in increased expression of ABCB4 mRNA

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

acetylcholinesterase

increases expression

licochalcone B results in increased expression of ACHE mRNA

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

acyl-CoA synthetase bubblegum family member 1

increases expression

licochalcone B results in increased expression of ACSBG1 mRNA

NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391

G

actin, alpha 1, skeletal muscle

increases expression

licochalcone B results in increased expression of ACTA1 mRNA

NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742

G

actinin alpha 3

increases expression

licochalcone B results in increased expression of ACTN3 mRNA

NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

decreases expression

licochalcone B results in decreased expression of ADAMTS5 mRNA

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

ArfGAP with dual PH domains 1

increases expression

licochalcone B results in increased expression of ADAP1 mRNA

NCBI chr12:15,323,913...15,376,110
Ensembl chr12:15,324,209...15,380,831

G

adenosine deaminase, tRNA-specific 3

increases expression

licochalcone B results in increased expression of ADAT3 mRNA

NCBI chr 7:9,109,070...9,113,673
Ensembl chr 7:9,101,187...9,115,340

G

adhesion G protein-coupled receptor G3

decreases expression

licochalcone B results in decreased expression of ADGRG3 mRNA

NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123

G

adhesion G protein-coupled receptor L2

decreases expression

licochalcone B results in decreased expression of ADGRL2 mRNA

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

adrenomedullin

increases expression

licochalcone B results in increased expression of ADM mRNA

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

adrenoceptor alpha 1D

increases expression

licochalcone B results in increased expression of ADRA1D mRNA

NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354

G

adrenoceptor alpha 2B

increases expression

licochalcone B results in increased expression of ADRA2B mRNA

NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355

G

adrenoceptor beta 2

increases expression

licochalcone B results in increased expression of ADRB2 mRNA

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

arylformamidase

increases expression

licochalcone B results in increased expression of AFMID mRNA

NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718

G

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

decreases expression

licochalcone B results in decreased expression of AGL mRNA

NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828

G

A-kinase anchoring protein 5

decreases expression

licochalcone B results in decreased expression of AKAP5 mRNA

NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578

G

aldo-keto reductase family 1 member B10

increases expression

licochalcone B results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldehyde dehydrogenase 1 family, member A1

increases expression

licochalcone B results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

ALG9, alpha-1,2-mannosyltransferase

decreases expression

licochalcone B results in decreased expression of ALG9 mRNA

NCBI chr 8:51,117,057...51,188,790
Ensembl chr 8:51,119,365...51,182,261

G

ALK and LTK ligand 2

increases expression

licochalcone B results in increased expression of ALKAL2 mRNA

NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234

G

arachidonate 12-lipoxygenase, 12S type

increases expression

licochalcone B results in increased expression of ALOX12 mRNA

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

G

arachidonate epidermal lipoxygenase 3

increases expression

licochalcone B results in increased expression of ALOXE3 mRNA

NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328

G

angiogenin

decreases expression

licochalcone B results in decreased expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

ankyrin repeat domain 1

increases expression

licochalcone B results in increased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

adaptor related protein complex 3 subunit beta 2

increases expression

licochalcone B results in increased expression of AP3B2 mRNA

NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191

G

adaptor related protein complex 5 subunit zeta 1

increases expression

licochalcone B results in increased expression of AP5Z1 mRNA

NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511

G

amyloid beta precursor protein binding family B member 1

increases expression

licochalcone B results in increased expression of APBB1 mRNA

NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627

G

apolipoprotein B receptor

decreases expression

licochalcone B results in decreased expression of APOBR mRNA

NCBI chr 1:181,169,019...181,173,206
Ensembl chr 1:181,168,916...181,173,528

G

apolipoprotein E

increases expression

licochalcone B results in increased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

activity-regulated cytoskeleton-associated protein

increases expression

licochalcone B results in increased expression of ARC mRNA

NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378

G

Rho guanine nucleotide exchange factor 33

increases expression

licochalcone B results in increased expression of ARHGEF33 mRNA

NCBI chr 6:14,582,922...14,715,014
Ensembl chr 6:14,551,495...14,725,292

G

ADP ribosylation factor like GTPase 4C

increases expression

licochalcone B results in increased expression of ARL4C mRNA

NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513

G

ADP-ribosylation factor like GTPase 4D

increases expression

licochalcone B results in increased expression of ARL4D mRNA

NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836

G

ADP-ribosylation factor like GTPase 6 interacting protein 4

increases expression

licochalcone B results in increased expression of ARL6IP4 mRNA

NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799

G

aryl hydrocarbon receptor nuclear translocator 2

decreases expression

licochalcone B results in decreased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

actin-related protein 2/3 complex inhibitor

decreases expression

licochalcone B results in decreased expression of ARPIN mRNA

NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124

G

acid sensing ion channel subunit family member 4

increases expression

licochalcone B results in increased expression of ASIC4 mRNA

NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

licochalcone B results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

ATCAY kinesin light chain interacting caytaxin

increases expression

licochalcone B results in increased expression of ATCAY mRNA

NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663

G

activating transcription factor 3

increases expression

licochalcone B results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

autophagy related 9B

increases expression

licochalcone B results in increased expression of ATG9B mRNA

NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651

G

ATM serine/threonine kinase

increases phosphorylation

licochalcone B results in increased phosphorylation of ATM protein

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase 13A4

increases expression

licochalcone B results in increased expression of ATP13A4 mRNA

NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933

G

ATPase Na+/K+ transporting subunit alpha 3

increases expression

licochalcone B results in increased expression of ATP1A3 mRNA

NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918

G

ATPase H+ transporting V0 subunit C

increases expression

licochalcone B results in increased expression of ATP6V0C mRNA

NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500

G

ATPase phospholipid transporting 9A (putative)

decreases expression

licochalcone B results in decreased expression of ATP9A mRNA

NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818

G

aurora kinase C

increases expression

licochalcone B results in increased expression of AURKC mRNA

NCBI chr 1:66,843,653...66,849,775
Ensembl chr 1:66,843,653...66,864,386

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

increases expression

licochalcone B results in increased expression of B3GNT4 mRNA

NCBI chr12:33,070,221...33,073,904
Ensembl chr12:33,060,416...33,073,854

G

beta-1,4-N-acetyl-galactosaminyl transferase 3

increases expression

licochalcone B results in increased expression of B4GALNT3 mRNA

NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321

G

BAG cochaperone 3

increases expression

licochalcone B results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BAR/IMD domain containing adaptor protein 2

increases expression

licochalcone B results in increased expression of BAIAP2 mRNA

NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134

G

BAI1-associated protein 3

increases expression

licochalcone B results in increased expression of BAIAP3 mRNA

NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019

G

BMP and activin membrane-bound inhibitor

increases expression

licochalcone B results in increased expression of BAMBI mRNA

NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060

G

BCL2 associated X, apoptosis regulator

increases expression

licochalcone B results in increased expression of BAX protein

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

increases expression

licochalcone B results in increased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCL2, apoptosis regulator

decreases expression

licochalcone B results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

brain expressed X-linked 1

increases expression

licochalcone B results in increased expression of BEX2 mRNA

NCBI chr X:99,219,014...99,220,518
Ensembl chr X:99,219,014...99,220,958

G

BICD family like cargo adaptor 2

increases expression

licochalcone B results in increased expression of BICDL2 mRNA

NCBI chr10:12,691,610...12,700,049
Ensembl chr10:12,691,610...12,700,049

G

BCL2-interacting killer

increases expression

licochalcone B results in increased expression of BIK mRNA

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

baculoviral IAP repeat-containing 5

decreases expression

licochalcone B results in decreased expression of BIRC5 protein

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

biliverdin reductase B

increases expression

licochalcone B results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

BMP-binding endothelial regulator

decreases expression

licochalcone B results in decreased expression of BMPER mRNA

NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256

G

bisphosphoglycerate mutase

increases expression

licochalcone B results in increased expression of BPGM mRNA

NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581

G

BRMS1, transcriptional repressor and anoikis regulator

increases expression

licochalcone B results in increased expression of BRMS1 mRNA

NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028

G

bone marrow stromal cell antigen 1

increases expression

licochalcone B results in increased expression of BST1 mRNA

NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180

G

BTB domain containing 8

decreases expression

licochalcone B results in decreased expression of BTBD8 mRNA

NCBI chr14:2,265,187...2,338,426
Ensembl chr14:2,266,454...2,334,393

G

BTG anti-proliferation factor 2

increases expression

licochalcone B results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

B and T lymphocyte associated

increases expression

licochalcone B results in increased expression of BTLA mRNA

NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181

G

similar to human chromosome 13 open reading frame 46

decreases expression

licochalcone B results in decreased expression of C13ORF46 mRNA

NCBI chr16:75,974,501...75,987,629
Ensembl chr16:75,975,463...75,987,628

G

similar to human chromosome 10 open reading frame 95

decreases expression

licochalcone B results in decreased expression of C10ORF95 mRNA

NCBI chr 1:245,210,228...245,212,080
Ensembl chr 1:245,210,973...245,211,602

G

similar to human chromosome 11 open reading frame 86

decreases expression

licochalcone B results in decreased expression of C11ORF86 mRNA

NCBI chr 1:201,784,009...201,785,916
Ensembl chr 1:201,784,009...201,785,916

G

complement C1q like 3

increases expression

licochalcone B results in increased expression of C1QL3 mRNA

NCBI chr17:76,119,344...76,129,170
Ensembl chr17:76,119,447...76,128,530

G

C1q and TNF related 4

increases expression

licochalcone B results in increased expression of C1QTNF4 mRNA

NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139

G

complement C5a receptor 2

decreases expression

licochalcone B results in decreased expression of C5AR2 mRNA

NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517

G

calcium binding protein 7

increases expression

licochalcone B results in increased expression of CABP7 mRNA

NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240

G

calcium voltage-gated channel auxiliary subunit alpha2delta 2

increases expression

licochalcone B results in increased expression of CACNA2D2 mRNA

NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173

G

calcium voltage-gated channel auxiliary subunit beta 2

decreases expression

licochalcone B results in decreased expression of CACNB2 mRNA

NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106

G

calbindin 2

increases expression

licochalcone B results in increased expression of CALB2 mRNA

NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438

G

caspase recruitment domain family, member 9

increases expression

licochalcone B results in increased expression of CARD9 mRNA

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

G

calcium responsive transcription factor

decreases expression

licochalcone B results in decreased expression of CARF mRNA

NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462

G

caspase 14

decreases expression

licochalcone B results in decreased expression of CASP14 mRNA

NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405

G

caspase 3

increases activity

licochalcone B results in increased activity of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions
increases cleavage

TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of CASP8 protein]

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

Cas scaffold protein family member 4

increases expression

licochalcone B results in increased expression of CASS4 mRNA

NCBI chr 3:161,162,520...161,202,523
Ensembl chr 3:161,163,436...161,202,186

G

cation channel sperm associated auxiliary subunit gamma

increases expression

licochalcone B results in increased expression of CATSPERG mRNA

NCBI chr 1:84,488,728...84,519,495
Ensembl chr 1:84,488,730...84,519,559

G

CACN subunit beta associated regulatory protein

increases expression

licochalcone B results in increased expression of CBARP mRNA

NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204

G

chromobox 4

increases expression

licochalcone B results in increased expression of CBX4 mRNA

NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706

G

coiled-coil domain containing 13

increases expression

licochalcone B results in increased expression of CCDC13 mRNA

NCBI chr 8:121,455,202...121,507,487
Ensembl chr 8:121,457,697...121,502,337

G

coiled-coil domain containing 148

increases expression

licochalcone B results in increased expression of CCDC148 mRNA

NCBI chr 3:43,356,885...43,631,999
Ensembl chr 3:43,356,892...43,631,991

G

coiled-coil domain containing 194

increases expression

licochalcone B results in increased expression of CCDC194 mRNA

NCBI chr16:18,205,099...18,209,310
Ensembl chr16:18,205,095...18,209,283

G

coiled-coil domain containing 68

decreases expression

licochalcone B results in decreased expression of CCDC68 mRNA

NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119

G

coiled-coil domain containing 9

increases expression

licochalcone B results in increased expression of CCDC9 mRNA

NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607

G

coiled-coil domain containing 96

increases expression

licochalcone B results in increased expression of CFAP184 mRNA

NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888

G

CCM2 like scaffold protein

increases expression

licochalcone B results in increased expression of CCM2L mRNA

NCBI chr 3:141,533,470...141,549,136
Ensembl chr 3:141,533,511...141,549,140

G

cellular communication network factor 1

increases expression

licochalcone B results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

increases expression

licochalcone B results in increased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin A2

decreases expression

licochalcone B results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression

licochalcone B results in decreased expression of CCNB1 protein

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin E1

increases expression

licochalcone B results in increased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

CD14 molecule

increases expression

licochalcone B results in increased expression of CD14 mRNA

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

Cd247 molecule

increases expression

licochalcone B results in increased expression of CD247 mRNA

NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263

G

CD27 molecule

increases expression

licochalcone B results in increased expression of CD27 mRNA

NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592

G

Cd4 molecule

increases expression

licochalcone B results in increased expression of CD4 mRNA

NCBI chr 4:157,668,878...157,695,366

G

CD79a molecule

increases expression

licochalcone B results in increased expression of CD79A mRNA

NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935

G

cell division cycle 25A

decreases expression

licochalcone B results in decreased expression of CDC25A protein

NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701

G

cell division cycle 25B

decreases expression

licochalcone B results in decreased expression of CDC25B protein

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

G

cell division cycle 34, ubiqiutin conjugating enzyme

increases expression

licochalcone B results in increased expression of CDC34 mRNA

NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186

G

CDC42 effector protein 2

increases expression

licochalcone B results in increased expression of CDC42EP2 mRNA

NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897

G

cadherin-related 23

increases expression

licochalcone B results in increased expression of CDH23 mRNA

NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419

G

cyclin-dependent kinase 1

decreases expression
multiple interactions

licochalcone B results in decreased expression of CDK1 mRNA
licochalcone B results in decreased expression of and results in decreased phosphorylation of CDK1 protein

PMID:24384411 PMID:35948134

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin dependent kinase 2

decreases expression

licochalcone B results in decreased expression of CDK2 mRNA

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 2 associated protein 2

increases expression

licochalcone B results in increased expression of CDK2AP2 mRNA

NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137

G

cyclin-dependent kinase 5 regulatory subunit 1

increases expression

licochalcone B results in increased expression of CDK5R1 mRNA

NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456

G

cyclin-dependent kinase 5 regulatory subunit 2

decreases expression

licochalcone B results in decreased expression of CDK5R2 mRNA

NCBI chr 9:76,416,251...76,417,719
Ensembl chr 9:76,416,062...76,418,344

G

cyclin-dependent kinase inhibitor 1A

increases expression

licochalcone B results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression

licochalcone B results in increased expression of CDKN1B protein

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

increases expression

licochalcone B results in increased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin dependent kinase inhibitor 2D

increases expression

licochalcone B results in increased expression of CDKN2D mRNA

NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674

G

CUGBP, Elav-like family member 5

increases expression

licochalcone B results in increased expression of CELF5 mRNA

NCBI chr 7:8,225,787...8,250,322
Ensembl chr 7:8,225,825...8,250,322

G

centromere protein E

decreases expression

licochalcone B results in decreased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

cilia and flagella associated protein 141

increases expression

licochalcone B results in increased expression of CFAP141 mRNA

NCBI chr 2:175,507,628...175,510,662
Ensembl chr 2:175,507,628...175,510,662

G

cilia and flagella associated protein 20

increases expression

licochalcone B results in increased expression of CFAP20 mRNA

NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558

G

cilia and flagella associated protein 43

increases expression

licochalcone B results in increased expression of CFAP43 mRNA

NCBI chr 1:246,625,259...246,712,438
Ensembl chr 1:246,625,262...246,712,443

G

cilia and flagella associated protein 99

increases expression

licochalcone B results in increased expression of CFAP99 mRNA

NCBI chr14:76,423,923...76,468,170
Ensembl chr14:76,410,555...76,468,125

G

complement factor properdin

increases expression

licochalcone B results in increased expression of CFP mRNA

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression

licochalcone B results in increased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

coiled-coil-helix-coiled-coil-helix domain containing 7

increases expression

licochalcone B results in increased expression of CHCHD7 mRNA

NCBI chr 5:16,957,127...16,961,682
Ensembl chr 5:16,957,188...16,961,184

G

checkpoint kinase 2

increases phosphorylation

licochalcone B results in increased phosphorylation of CHEK2 protein

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

cholinergic receptor, muscarinic 3

decreases expression

licochalcone B results in decreased expression of CHRM3 mRNA

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

cholinergic receptor, muscarinic 4

increases expression

licochalcone B results in increased expression of CHRM4 mRNA

NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159

G

cholinergic receptor nicotinic alpha 3 subunit

increases expression

licochalcone B results in increased expression of CHRNA3 mRNA

NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165

G

cholinergic receptor nicotinic alpha 7 subunit

increases expression

licochalcone B results in increased expression of CHRNA7 mRNA

NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240

G

cholinergic receptor nicotinic delta subunit

decreases expression

licochalcone B results in decreased expression of CHRND mRNA

NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833

G

cholinergic receptor nicotinic gamma subunit

decreases expression

licochalcone B results in decreased expression of CHRNG mRNA

NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482

G

ciliary microtubule inner protein 2A

increases expression

licochalcone B results in increased expression of CIMIP2A mRNA

NCBI chr 3:8,030,548...8,038,370
Ensembl chr 3:8,033,246...8,037,961

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

increases expression

licochalcone B results in increased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

CDC28 protein kinase regulatory subunit 2

increases expression

licochalcone B results in increased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

claudin 19

increases expression

licochalcone B results in increased expression of CLDN19 mRNA

NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227

G

claudin 6

increases expression

licochalcone B results in increased expression of CLDN6 mRNA

NCBI chr10:12,710,302...12,713,987
Ensembl chr10:12,709,960...12,715,973

G

claudin 9

increases expression

licochalcone B results in increased expression of CLDN9 mRNA

NCBI chr10:12,714,137...12,715,568

G

clusterin

increases expression

licochalcone B results in increased expression of CLU mRNA

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

cornichon family AMPA receptor auxiliary protein 3

increases expression

licochalcone B results in increased expression of CNIH3 mRNA

NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121

G

cyclin and CBS domain divalent metal cation transport mediator 4

increases expression

licochalcone B results in increased expression of CNNM4 mRNA

NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942

G

contactin 2

increases expression

licochalcone B results in increased expression of CNTN2 mRNA

NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887

G

collagen type VI alpha 2 chain

increases expression

licochalcone B results in increased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

cytochrome c oxidase subunit 8C

increases expression

licochalcone B results in increased expression of COX8C mRNA

NCBI chr 6:122,028,566...122,029,889
Ensembl chr 6:122,028,566...122,029,889

G

complexin 2

increases expression

licochalcone B results in increased expression of CPLX2 mRNA

NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855

G

carbamoyl-phosphate synthase 1

decreases expression

licochalcone B results in decreased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

cysteine-rich secretory protein LCCL domain containing 1

decreases expression

licochalcone B results in decreased expression of CRISPLD1 mRNA

NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926

G

cysteine-rich secretory protein LCCL domain containing 2

increases expression

licochalcone B results in increased expression of CRISPLD2 mRNA

NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465

G

crystallin, beta A1

increases expression

licochalcone B results in increased expression of CRYBA1 mRNA

NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726

G

crystallin beta-gamma domain containing 1

decreases expression

licochalcone B results in decreased expression of CRYBG1 mRNA

NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392

G

crystallin, mu

increases expression

licochalcone B results in increased expression of CRYM mRNA

NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633

G

cysteine and serine rich nuclear protein 1

increases expression

licochalcone B results in increased expression of CSRNP1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cysteine and serine rich nuclear protein 2

increases expression

licochalcone B results in increased expression of CSRNP2 mRNA

NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075

G

cysteine and glycine-rich protein 2

increases expression

licochalcone B results in increased expression of CSRP2 mRNA

NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745

G

chymotrypsin C

increases expression

licochalcone B results in increased expression of CTRC mRNA

NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528

G

CXXC finger protein 4

decreases expression

licochalcone B results in decreased expression of CXXC4 mRNA

NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365

G

cytoglobin

decreases expression

licochalcone B results in decreased expression of CYGB mRNA

NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

licochalcone B results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

dishevelled-binding antagonist of beta-catenin 3

increases expression

licochalcone B results in increased expression of DACT3 mRNA

NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630

G

dicarbonyl and L-xylulose reductase

increases expression

licochalcone B results in increased expression of DCXR mRNA

NCBI chr10:106,006,404...106,008,293

G

DNA-damage inducible transcript 3

increases expression

licochalcone B results in increased expression of DDIT3 mRNA; licochalcone B results in increased expression of DDIT3 protein

PMID:33647349 PMID:35948134

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

discoidin domain receptor tyrosine kinase 2

increases expression

licochalcone B results in increased expression of DDR2 mRNA

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

DEXD/H-box helicase 60

decreases expression

licochalcone B results in decreased expression of DDX60 mRNA

NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526

G

death effector domain containing 2

increases expression

licochalcone B results in increased expression of DEDD2 mRNA

NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714

G

diacylglycerol O-acyltransferase 1

increases expression

licochalcone B results in increased expression of DGAT1 mRNA

NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299

G

dihydrodiol dehydrogenase

increases expression

licochalcone B results in increased expression of DHDH mRNA

NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197

G

DEXH-box helicase 58

increases expression

licochalcone B results in increased expression of DHX58 mRNA

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

G

iodothyronine deiodinase 2

decreases expression

licochalcone B results in decreased expression of DIO2 mRNA

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

iodothyronine deiodinase 3

increases expression

licochalcone B results in increased expression of DIO3 mRNA

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

dispatched RND transporter family member 3

increases expression

licochalcone B results in increased expression of DISP3 mRNA

NCBI chr 5:158,672,015...158,720,806
Ensembl chr 5:158,672,015...158,720,806

G

DIX domain containing 1

decreases expression

licochalcone B results in decreased expression of DIXDC1 mRNA

NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090

G

discs large MAGUK scaffold protein 3

decreases expression

licochalcone B results in decreased expression of DLG3 mRNA

NCBI chr X:65,859,653...65,911,887
Ensembl chr X:65,860,172...65,910,322

G

delta like canonical Notch ligand 4

increases expression

licochalcone B results in increased expression of DLL4 mRNA

NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931

G

distal-less homeobox 2

increases expression

licochalcone B results in increased expression of DLX2 mRNA

NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597

G

deleted in malignant brain tumors 1

decreases expression

licochalcone B results in decreased expression of DMBT1 mRNA

NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478

G

dynein, axonemal, heavy chain 3

increases expression

licochalcone B results in increased expression of DNAH3 mRNA

NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474

G

DnaJ heat shock protein family (Hsp40) member A4

increases expression

licochalcone B results in increased expression of DNAJA4 mRNA

NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

licochalcone B results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member C28

decreases expression

licochalcone B results in decreased expression of DNAJC28 mRNA

NCBI chr11:30,855,566...30,858,386
Ensembl chr11:30,853,526...30,858,441

G

dedicator of cyto-kinesis 3

increases expression

licochalcone B results in increased expression of DOCK3 mRNA

NCBI chr 8:107,552,462...107,903,527
Ensembl chr 8:107,552,463...107,903,514

G

Dr1 associated protein 1

increases expression

licochalcone B results in increased expression of DRAP1 mRNA

NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425

G

dynein regulatory complex subunit 1

increases expression

licochalcone B results in increased expression of DRC1 mRNA

NCBI chr 6:26,025,004...26,059,438
Ensembl chr 6:26,025,005...26,059,414

G

deltex E3 ubiquitin ligase 3L

decreases expression

licochalcone B results in decreased expression of DTX3L mRNA

NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538

G

dual specificity phosphatase 2

increases expression

licochalcone B results in increased expression of DUSP2 mRNA

NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499

G

dual specificity phosphatase 5

increases expression

licochalcone B results in increased expression of DUSP5 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dual specificity phosphatase 7

increases expression

licochalcone B results in increased expression of DUSP7 mRNA

NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404

G

epididymal protein 13

decreases expression

licochalcone B results in decreased expression of EDDM13 mRNA

NCBI chr 1:67,630,905...67,656,404
Ensembl chr 1:67,626,244...67,657,342

G

endothelin receptor type A

decreases expression

licochalcone B results in decreased expression of EDNRA mRNA

NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049

G

estrogen-induced osteoclastogenesis regulator 1

increases expression

licochalcone B results in increased expression of EEIG1 mRNA

NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643

G

ephrin B2

increases expression

licochalcone B results in increased expression of EFNB2 mRNA

NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391

G

ephrin B3

increases expression

licochalcone B results in increased expression of EFNB3 mRNA

NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471

G

EGF-like-domain, multiple 8

decreases expression

licochalcone B results in decreased expression of EGFL8 mRNA

NCBI chr20:4,132,930...4,136,024
Ensembl chr20:4,133,629...4,136,018

G

early growth response 1

increases expression

licochalcone B results in increased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 3

increases expression

licochalcone B results in increased expression of EGR3 mRNA

NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627

G

EH-domain containing 1

increases expression

licochalcone B results in increased expression of EHD1 mRNA

NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212

G

ets homologous factor

decreases expression

licochalcone B results in decreased expression of EHF mRNA

NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997

G

eukaryotic translation initiation factor 2 alpha kinase 3

decreases expression

licochalcone B results in decreased expression of EIF2AK3 protein

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 4A1

increases expression

licochalcone B results in increased expression of EIF4A1 mRNA

NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858

G

eukaryotic translation initiation factor 4A3

increases expression

licochalcone B results in increased expression of EIF4A3 mRNA

NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057

G

ER membrane protein complex subunit 9

increases expression

licochalcone B results in increased expression of EMC9 mRNA

NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098

G

endo-beta-N-acetylglucosaminidase

increases expression

licochalcone B results in increased expression of ENGASE mRNA

NCBI chr10:103,707,169...103,719,833
Ensembl chr10:103,707,169...103,719,819

G

Eph receptor A2

increases expression

licochalcone B results in increased expression of EPHA2 mRNA

NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117

G

Eph receptor A3

decreases expression

licochalcone B results in decreased expression of EPHA3 mRNA

NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900

G

epiplakin 1

increases expression

licochalcone B results in increased expression of EPPK1 mRNA

NCBI chr 7:107,816,919...107,842,946
Ensembl chr 7:107,817,693...107,831,159

G

ES cell expressed Ras

increases expression

licochalcone B results in increased expression of ERAS mRNA

NCBI chr X:14,573,987...14,578,455
Ensembl chr X:14,573,987...14,578,374

G

Ets2 repressor factor

increases expression

licochalcone B results in increased expression of ERF mRNA

NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388

G

ER lipid raft associated 2

decreases expression

licochalcone B results in decreased expression of ERLIN2 mRNA

NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671

G

espin

increases expression

licochalcone B results in increased expression of ESPN mRNA

NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256

G

eva-1 homolog B

increases expression

licochalcone B results in increased expression of EVA1B mRNA

NCBI chr 5:138,427,088...138,429,602
Ensembl chr 5:138,427,151...138,432,433

G

exocyst complex component 3-like 2

increases expression

licochalcone B results in increased expression of EXOC3L2 mRNA

NCBI chr 1:79,113,784...79,145,359
Ensembl chr 1:79,112,506...79,145,465

G

coagulation factor II (thrombin) receptor

decreases expression

licochalcone B results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

family with sequence similarity 117, member A

increases expression

licochalcone B results in increased expression of FAM117A mRNA

NCBI chr10:80,281,411...80,325,345
Ensembl chr10:80,281,408...80,325,343

G

family with sequence similarity 222, member A

increases expression

licochalcone B results in increased expression of FAM222A mRNA

NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682

G

family with sequence similarity 228, member B

increases expression

licochalcone B results in increased expression of FAM228B mRNA

NCBI chr 6:27,754,505...27,786,578
Ensembl chr 6:27,754,506...27,786,537

G

family with sequence similarity 43, member A

increases expression

licochalcone B results in increased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

family with sequence similarity 78, member A

decreases expression

licochalcone B results in decreased expression of FAM78A mRNA

NCBI chr 3:15,355,958...15,376,330
Ensembl chr 3:15,355,955...15,373,812

G

family with sequence similarity 89, member B

increases expression

licochalcone B results in increased expression of FAM89B mRNA

NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367

G

family with sequence similarity 90 member A1A

increases expression

licochalcone B results in increased expression of FAM90A1 mRNA

NCBI chr16:70,098,439...70,106,147
Ensembl chr16:70,098,740...70,101,241

G

fibrillarin-like 1

increases expression

licochalcone B results in increased expression of FBLL1 mRNA

NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299

G

F-box protein 32

increases expression

licochalcone B results in increased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

Fc gamma binding protein

increases expression

licochalcone B results in increased expression of FCGBP mRNA

NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083

G

Fc gamma receptor 1A

increases expression

licochalcone B results in increased expression of FCGR1A mRNA

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

G

fer-1-like family member 5

increases expression

licochalcone B results in increased expression of FER1L5 mRNA

NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425

G

fibroblast growth factor 18

increases expression

licochalcone B results in increased expression of FGF18 mRNA

NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818

G

fibroblast growth factor 22

increases expression

licochalcone B results in increased expression of FGF22 mRNA

NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486

G

fibroblast growth factor receptor 3

increases expression

licochalcone B results in increased expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

fat storage-inducing transmembrane protein 1

increases expression

licochalcone B results in increased expression of FITM1 mRNA

NCBI chr15:29,064,746...29,066,015
Ensembl chr15:29,064,707...29,066,015

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

licochalcone B results in increased expression of FOS mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of FOS protein]

PMID:25451593 PMID:33647349

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression

licochalcone B results in increased expression of FOSB mRNA

NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465

G

FOS like 1, AP-1 transcription factor subunit

increases expression

licochalcone B results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box A3

increases expression

licochalcone B results in increased expression of FOXA3 mRNA

NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box D1

increases expression

licochalcone B results in increased expression of FOXD1 mRNA

NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978

G

forkhead box E3

increases expression

licochalcone B results in increased expression of FOXE3 mRNA

NCBI chr 5:128,444,912...128,446,494
Ensembl chr 5:128,445,594...128,446,454

G

forkhead box P4

increases expression

licochalcone B results in increased expression of FOXP4 mRNA

NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879

G

Frey regulator of sperm-oocyte fusion 1

increases expression

licochalcone B results in increased expression of FREY1 mRNA

NCBI chr 3:78,354,303...78,355,055
Ensembl chr 3:78,354,303...78,355,055

G

FSHD region gene 2

increases expression

licochalcone B results in increased expression of FRG2 mRNA

NCBI chr14:80,427,260...80,429,560
Ensembl chr14:80,427,673...80,429,181

G

FRY microtubule binding protein

decreases expression

licochalcone B results in decreased expression of FRY mRNA

NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116

G

frizzled-related protein

increases expression

licochalcone B results in increased expression of FRZB mRNA

NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208

G

fucosyltransferase 1

decreases expression

licochalcone B results in decreased expression of FUT1 mRNA

NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616

G

FYVE and coiled-coil domain autophagy adaptor 1

decreases expression

licochalcone B results in decreased expression of FYCO1 mRNA

NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021

G

frizzled class receptor 7

increases expression

licochalcone B results in increased expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

gamma-aminobutyric acid type A receptor subunit rho 2

increases expression

licochalcone B results in increased expression of GABRR2 mRNA

NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809

G

growth arrest and DNA-damage-inducible, alpha

increases expression

licochalcone B results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, beta

increases expression

licochalcone B results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

polypeptide N-acetylgalactosaminyltransferase-like 6

decreases expression

licochalcone B results in decreased expression of GALNTL6 mRNA

NCBI chr16:31,192,880...32,443,979
Ensembl chr16:31,186,462...32,441,960

G

galanin receptor 2

increases expression

licochalcone B results in increased expression of GALR2 mRNA

NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176

G

GATA binding protein 2

increases expression

licochalcone B results in increased expression of GATA2 mRNA

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

G

GATA binding protein 3

increases expression

licochalcone B results in increased expression of GATA3 mRNA

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

G

gastrulation brain homeobox 2

increases expression

licochalcone B results in increased expression of GBX2 mRNA

NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212

G

glial cells missing transcription factor 1

increases expression

licochalcone B results in increased expression of GCM1 mRNA

NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924

G

GTP binding protein overexpressed in skeletal muscle

increases expression

licochalcone B results in increased expression of GEM mRNA

NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222

G

guided entry of tail-anchored proteins factor 4

increases expression

licochalcone B results in increased expression of GET4 mRNA

NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053

G

growth factor independent 1 transcriptional repressor

decreases expression

licochalcone B results in decreased expression of GFI1 mRNA

NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814

G

glutamine-fructose-6-phosphate transaminase 2

increases expression

licochalcone B results in increased expression of GFPT2 mRNA

NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329

G

GDNF family receptor alpha 3

increases expression

licochalcone B results in increased expression of GFRA3 mRNA

NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105

G

GIPC PDZ domain containing family, member 2

increases expression

licochalcone B results in increased expression of GIPC2 mRNA

NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236

G

G protein subunit gamma 13

increases expression

licochalcone B results in increased expression of GNG13 mRNA

NCBI chr10:14,741,179...14,743,083
Ensembl chr10:14,741,239...14,743,083

G

glutathione S-transferase, mu 5-like

increases expression

licochalcone B results in increased expression of GSTM5 mRNA

NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961

G

granzyme M

increases expression

licochalcone B results in increased expression of GZMM mRNA

NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665

G

H1.4 linker histone, cluster member

increases expression

licochalcone B results in increased expression of H1-4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

H2A clustered histone 12

increases expression

licochalcone B results in increased expression of H2AC12 mRNA

NCBI chr17:42,486,415...42,486,880
Ensembl chr17:42,486,415...42,486,941

G

H2A clustered histone 21

increases expression

licochalcone B results in increased expression of H2AC21 mRNA

NCBI chr 2:183,779,355...183,779,788

G

H2A.X variant histone

increases expression
increases phosphorylation

licochalcone B results in increased expression of H2AX mRNA
licochalcone B results in increased phosphorylation of H2AX protein

PMID:33647349 PMID:35948134

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

H2B clustered histone 12

increases expression

licochalcone B results in increased expression of H2BC12 mRNA

NCBI chr17:42,485,699...42,486,162

G

H2B clustered histone 18

increases expression

licochalcone B results in increased expression of H2BC18 mRNA

NCBI chr 2:183,838,331...183,842,769
Ensembl chr 2:183,838,334...183,841,529

G

H2B clustered histone 6

increases expression

licochalcone B results in increased expression of H2BC6 mRNA

NCBI chr17:41,520,775...41,521,238

G

H2B clustered histone 8

increases expression

licochalcone B results in increased expression of H2BC8 mRNA

NCBI chr17:42,708,658...42,709,408

G

H2B clustered histone 9

increases expression

licochalcone B results in increased expression of H2BC9 mRNA

NCBI chr17:42,470,593...42,478,590

G

H3 clustered histone 1

increases expression

licochalcone B results in increased expression of H3C1 mRNA

NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856

G

H3 clustered histone 13

increases expression

licochalcone B results in increased expression of H3C13 mRNA

NCBI chr17:41,531,502...41,531,971
Ensembl chr 2:183,795,504...183,809,469
Ensembl chr17:183,795,504...183,809,469
Ensembl chr 2:183,795,504...183,809,469
Ensembl chr17:183,795,504...183,809,469
Ensembl chr17:183,795,504...183,809,469
Ensembl chr 2:183,795,504...183,809,469

G

hepcidin antimicrobial peptide

increases expression

licochalcone B results in increased expression of HAMP mRNA

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hyaluronan and proteoglycan link protein 2

increases expression

licochalcone B results in increased expression of HAPLN2 mRNA

NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588

G

hyaluronan and proteoglycan link protein 3

increases expression

licochalcone B results in increased expression of HAPLN3 mRNA

NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177

G

hyaluronan synthase 1

increases expression

licochalcone B results in increased expression of HAS1 mRNA

NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397

G

hyaluronan synthase 3

increases expression

licochalcone B results in increased expression of HAS3 mRNA

NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592

G

hemoglobin alpha, adult chain 2

increases expression

licochalcone B results in increased expression of HBA1 mRNA

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392

G

heparin-binding EGF-like growth factor

increases expression

licochalcone B results in increased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

licochalcone B results in increased expression of HERPUD1 mRNA

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 6

increases expression

licochalcone B results in increased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

hes family bHLH transcription factor 7

increases expression

licochalcone B results in increased expression of HES7 mRNA

NCBI chr10:53,824,124...53,828,934
Ensembl chr10:53,825,574...53,828,097

G

HIC ZBTB transcriptional repressor 2

increases expression

licochalcone B results in increased expression of HIC2 mRNA

NCBI chr11:83,737,075...83,789,554
Ensembl chr11:83,738,874...83,767,484

G

homeodomain interacting protein kinase 4

increases expression

licochalcone B results in increased expression of HIPK4 mRNA

NCBI chr 1:82,810,708...82,821,080
Ensembl chr 1:82,810,708...82,821,077

G

histone cluster 1 H2A family member F

increases expression

licochalcone B results in increased expression of H2AC8 mRNA

NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796

G

histone cluster 1 H2B family member D

increases expression

licochalcone B results in increased expression of H2BC5 mRNA

NCBI chr17:42,792,887...42,793,268

G

histone cluster 1 H2B family member Q

increases expression

licochalcone B results in increased expression of H2BC7 mRNA

NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153

G

histone cluster 1 H4 family member B

increases expression

licochalcone B results in increased expression of H4C9 mRNA

NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370

G

histone cluster 1, H4m

increases expression

licochalcone B results in increased expression of H4C1 mRNA

NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958

G

histone cluster 2 H2B family member E

increases expression

licochalcone B results in increased expression of H2BC11 mRNA

NCBI chr 2:183,780,583...183,783,030

G

heme oxygenase 1

increases expression

licochalcone B results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

homer scaffold protein 2

increases expression

licochalcone B results in increased expression of HOMER2 mRNA

NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772

G

homeo box C4

decreases expression

licochalcone B results in decreased expression of HOXC4 mRNA

NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133

G

hemopexin

increases expression

licochalcone B results in increased expression of HPX mRNA

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

G

heat shock protein family A (Hsp70) member 1A

increases expression

licochalcone B results in increased expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

licochalcone B results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 1 like

increases expression

licochalcone B results in increased expression of HSPA1L mRNA

NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

licochalcone B results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

heat shock protein family A (Hsp70) member 8

increases expression

licochalcone B results in increased expression of HSPA8 mRNA

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family B (small) member 8

increases expression

licochalcone B results in increased expression of HSPB8 mRNA

NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185

G

heat shock protein family B (small) member 9

increases expression

licochalcone B results in increased expression of HSPB9 mRNA

NCBI chr10:85,641,284...85,641,929
Ensembl chr10:85,641,284...85,641,929

G

heat shock protein family H (Hsp110) member 1

increases expression

licochalcone B results in increased expression of HSPH1 mRNA

NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224

G

HUS1 checkpoint clamp component B

increases expression

licochalcone B results in increased expression of HUS1B mRNA

NCBI chr17:33,534,032...33,535,199

G

inhibitor of DNA binding 2

increases expression

licochalcone B results in increased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

immediate early response 5

increases expression

licochalcone B results in increased expression of IER5 mRNA

NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227

G

immediate early response 5-like

increases expression

licochalcone B results in increased expression of IER5L mRNA

NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647

G

IFI30, lysosomal thiol reductase

increases expression

licochalcone B results in increased expression of IFI30 mRNA

NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175

G

interferon induced with helicase C domain 1

decreases expression

licochalcone B results in decreased expression of IFIH1 mRNA

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

immunoglobulin superfamily, member 11

increases expression

licochalcone B results in increased expression of IGSF11 mRNA

NCBI chr11:61,733,139...61,884,059
Ensembl chr11:61,733,144...61,868,348

G

interleukin 1 alpha

decreases expression

licochalcone B results in decreased expression of IL1A mRNA

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

decreases expression
multiple interactions

licochalcone B results in decreased expression of IL1B mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]

PMID:25451593 PMID:33647349

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 1

decreases expression

licochalcone B results in decreased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 2 receptor subunit beta

decreases expression

licochalcone B results in decreased expression of IL2RB mRNA

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

G

interleukin 6

multiple interactions
decreases expression

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
licochalcone B results in decreased expression of IL6 mRNA

PMID:25451593 PMID:33647349

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

InaF-motif containing 1

increases expression

licochalcone B results in increased expression of INAFM1 mRNA

NCBI chr 1:76,976,808...76,978,292

G

inhibin subunit beta E

decreases expression

licochalcone B results in decreased expression of INHBE mRNA

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

inka box actin regulator 1

increases expression

licochalcone B results in increased expression of INKA1 mRNA

NCBI chr 8:108,674,263...108,675,953
Ensembl chr 8:108,674,263...108,675,953

G

INSM transcriptional repressor 2

increases expression

licochalcone B results in increased expression of INSM2 mRNA

NCBI chr 6:72,973,861...72,976,453

G

interferon regulatory factor 7

increases expression

licochalcone B results in increased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

immunity related GTPase cinema

increases expression

licochalcone B results in increased expression of IRGC mRNA

NCBI chr 1:80,020,114...80,025,797
Ensembl chr 1:80,020,079...80,025,802

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

increases expression

licochalcone B results in increased expression of JMJD6 mRNA

NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182

G

junctophilin 4

increases expression

licochalcone B results in increased expression of JPH4 mRNA

NCBI chr15:28,579,579...28,588,903
Ensembl chr15:28,571,568...28,587,573

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

licochalcone B results in increased expression of JUN mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of JUN protein]

PMID:25451593 PMID:33647349

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

licochalcone B results in increased expression of JUNB mRNA

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression

licochalcone B results in increased expression of JUND mRNA

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

KN motif and ankyrin repeat domains 3

increases expression

licochalcone B results in increased expression of KANK3 mRNA

NCBI chr 7:14,594,358...14,607,675
Ensembl chr 7:14,594,422...14,607,675

G

kelch repeat and BTB domain containing 8

increases expression

licochalcone B results in increased expression of KBTBD8 mRNA

NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697

G

potassium voltage-gated channel subfamily B member 1

increases expression

licochalcone B results in increased expression of KCNB1 mRNA

NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194

G

potassium voltage-gated channel modifier subfamily G member 2

increases expression

licochalcone B results in increased expression of KCNG2 mRNA

NCBI chr18:73,742,224...73,810,420
Ensembl chr18:73,743,074...73,808,723

G

potassium voltage-gated channel subfamily H member 5

decreases expression

licochalcone B results in decreased expression of KCNH5 mRNA

NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107

G

potassium two pore domain channel subfamily K member 3

decreases expression

licochalcone B results in decreased expression of KCNK3 mRNA

NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153

G

potassium two pore domain channel subfamily K member 4

increases expression

licochalcone B results in increased expression of KCNK4 mRNA

NCBI chr 1:204,117,941...204,129,494
Ensembl chr 1:204,114,572...204,125,925

G

potassium channel tetramerization domain containing 5

increases expression

licochalcone B results in increased expression of KCTD5 mRNA

NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209

G

keratinocyte differentiation factor 1

increases expression

licochalcone B results in increased expression of KDF1 mRNA

NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878

G

KIAA0825 homolog

decreases expression

licochalcone B results in decreased expression of KIAA0825 mRNA

NCBI chr 2:6,874,474...7,437,032
Ensembl chr 2:6,874,539...7,434,521

G

kinesin family member 5A

increases expression

licochalcone B results in increased expression of KIF5A mRNA

NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858

G

kirre like nephrin family adhesion molecule 2

increases expression

licochalcone B results in increased expression of KIRREL2 mRNA

NCBI chr 1:85,708,793...85,718,670
Ensembl chr 1:85,708,793...85,718,670

G

KLF transcription factor 2

increases expression

licochalcone B results in increased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KLF transcription factor 4

increases expression

licochalcone B results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

kelch-like family member 13

decreases expression

licochalcone B results in decreased expression of KLHL13 mRNA

NCBI chr X:113,942,309...114,107,299
Ensembl chr X:113,942,309...114,107,321

G

kelch-like family member 21

increases expression

licochalcone B results in increased expression of KLHL21 mRNA

NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545

G

kelch-like family member 25

increases expression

licochalcone B results in increased expression of KLHL25 mRNA

NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227

G

kinase non-catalytic C-lobe domain containing 1

decreases expression

licochalcone B results in decreased expression of KNDC1 mRNA

NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362

G

keratin 16

increases expression

licochalcone B results in increased expression of KRT16 mRNA

NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799

G

lymphocyte activating 3

increases expression

licochalcone B results in increased expression of LAG3 mRNA

NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404

G

low density lipoprotein receptor class A domain containing 2

increases expression

licochalcone B results in increased expression of LDLRAD2 mRNA

NCBI chr 5:149,778,795...149,788,335
Ensembl chr 5:149,779,675...149,787,140

G

low density lipoprotein receptor class A domain containing 4

increases expression

licochalcone B results in increased expression of LDLRAD4 mRNA

NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238

G

leukocyte receptor cluster member 1

increases expression

licochalcone B results in increased expression of LENG1 mRNA

NCBI chr 1:65,551,983...65,556,915
Ensembl chr 1:65,551,983...65,556,915

G

galectin 4

increases expression

licochalcone B results in increased expression of LGALS4 mRNA

NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481

G

leucine-rich repeat LGI family, member 4

increases expression

licochalcone B results in increased expression of LGI4 mRNA

NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874

G

lengsin, lens protein with glutamine synthetase domain

decreases expression

licochalcone B results in decreased expression of LGSN mRNA

NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907

G

luteinizing hormone subunit beta

increases expression

licochalcone B results in increased expression of LHB mRNA

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

ligand of numb-protein X 1

decreases expression

licochalcone B results in decreased expression of LNX1 mRNA

NCBI chr14:33,514,429...33,617,086
Ensembl chr14:33,514,436...33,617,086

G

small ubiquitin-related modifier 2-like

increases expression

licochalcone B results in increased expression of SUMO4 mRNA

NCBI chr11:79,163,457...79,164,088
Ensembl chr11:79,163,634...79,163,960

G

leucine rich repeat and fibronectin type III domain containing 1

decreases expression

licochalcone B results in decreased expression of LRFN1 mRNA

NCBI chr 1:83,742,442...83,761,450
Ensembl chr 1:83,682,964...83,761,449

G

leucine-rich repeats and guanylate kinase domain containing

decreases expression

licochalcone B results in decreased expression of LRGUK mRNA

NCBI chr 4:62,647,222...62,770,268
Ensembl chr 4:62,647,264...62,770,319

G

leucine rich repeat containing 15

increases expression

licochalcone B results in increased expression of LRRC15 mRNA

NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267

G

leucine rich repeat containing 43

increases expression

licochalcone B results in increased expression of LRRC43 mRNA

NCBI chr12:33,074,149...33,092,257
Ensembl chr12:33,074,150...33,095,082

G

leucine rich repeat containing 8 VRAC subunit A

increases expression

licochalcone B results in increased expression of LRRC8A mRNA

NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202

G

leucine-rich repeats and IQ motif containing 3

decreases expression

licochalcone B results in decreased expression of LRRIQ3 mRNA

NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339

G

leucine rich repeat neuronal 4

increases expression

licochalcone B results in increased expression of LRRN4 mRNA

NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831

G

leucine-rich single-pass membrane protein 1

increases expression

licochalcone B results in increased expression of LSMEM1 mRNA

NCBI chr 6:57,251,720...57,261,590
Ensembl chr 6:57,252,056...57,261,653

G

latent transforming growth factor beta binding protein 1

decreases expression

licochalcone B results in decreased expression of LTBP1 mRNA

NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349

G

lymphocyte antigen 6 family member G6C

increases expression

licochalcone B results in increased expression of LY6G6C mRNA

NCBI chr20:3,753,632...3,757,205
Ensembl chr20:3,753,632...3,758,867

G

MAF bZIP transcription factor A

increases expression

licochalcone B results in increased expression of MAFA mRNA

NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690

G

MAF bZIP transcription factor B

increases expression

licochalcone B results in increased expression of MAFB mRNA

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

MAF bZIP transcription factor F

increases expression

licochalcone B results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

MAGE family member B3

increases expression

licochalcone B results in increased expression of MAGEB3 mRNA

NCBI chr X:50,865,484...50,866,479
Ensembl chr X:50,865,484...50,866,479

G

mastermind-like transcriptional coactivator 2

decreases expression

licochalcone B results in decreased expression of MAML2 mRNA

NCBI chr 8:10,268,611...10,588,307
Ensembl chr 8:10,268,665...10,587,107

G

mannosidase, alpha, class 1C, member 1

increases expression

licochalcone B results in increased expression of MAN1C1 mRNA

NCBI chr 5:146,774,282...146,913,257
Ensembl chr 5:146,775,842...146,913,421

G

MANSC domain containing 1

decreases expression

licochalcone B results in decreased expression of MANSC1 mRNA

NCBI chr 4:167,438,817...167,459,047
Ensembl chr 4:167,439,071...167,479,606

G

microtubule-associated protein 1A

increases expression

licochalcone B results in increased expression of MAP1A mRNA

NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899

G

mitogen activated protein kinase kinase 3

increases expression

licochalcone B results in increased expression of MAP2K3 mRNA

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

G

mitogen-activated protein kinase kinase kinase 14

increases expression

licochalcone B results in increased expression of MAP3K14 mRNA

NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523

G

MAP7 domain containing 2

increases expression

licochalcone B results in increased expression of MAP7D2 mRNA

NCBI chr X:35,372,453...35,488,073
Ensembl chr X:35,372,700...35,488,091

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
licochalcone B results in increased phosphorylation of MAPK1 protein

PMID:25451593 PMID:35948134

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
licochalcone B results in increased phosphorylation of MAPK3 protein

PMID:25451593 PMID:35948134

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions
increases phosphorylation

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
licochalcone B results in increased phosphorylation of MAPK8 protein

PMID:25451593 PMID:35948134

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 8 interacting protein 1

increases expression

licochalcone B results in increased expression of MAPK8IP1 mRNA

NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884

G

mitogen-activated protein kinase 9

multiple interactions
increases phosphorylation

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]
licochalcone B results in increased phosphorylation of MAPK9 protein

PMID:25451593 PMID:35948134

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

membrane associated ring-CH-type finger 1

decreases expression

licochalcone B results in decreased expression of MARCHF1 mRNA

NCBI chr16:23,255,551...24,114,290
Ensembl chr16:23,258,799...24,114,277

G

MARCKS-like 1

increases expression

licochalcone B results in increased expression of MARCKSL1 mRNA

NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817

G

MARCO like

decreases expression

licochalcone B results in decreased expression of MARCOL mRNA

NCBI chr18:36,448,714...36,455,171

G

MBL associated serine protease 1

decreases expression

licochalcone B results in decreased expression of MASP1 mRNA

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

G

melanocortin 5 receptor

increases expression

licochalcone B results in increased expression of MC5R mRNA

NCBI chr18:61,915,188...61,920,229
Ensembl chr18:61,915,188...61,920,229

G

mucolipin TRP cation channel 1

increases expression

licochalcone B results in increased expression of MCOLN1 mRNA

NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252

G

MyoD family inhibitor

increases expression

licochalcone B results in increased expression of MDFI mRNA

NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217

G

MAM domain containing glycosylphosphatidylinositol anchor 1

increases expression

licochalcone B results in increased expression of MDGA1 mRNA

NCBI chr20:7,900,327...7,964,309
Ensembl chr20:7,904,358...7,963,471

G

Meis homeobox 1

decreases expression

licochalcone B results in decreased expression of MEIS1 mRNA

NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265

G

mesenchyme homeobox 1

decreases expression

licochalcone B results in decreased expression of MEOX1 mRNA

NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660

G

meteorin-like, glial cell differentiation regulator

increases expression

licochalcone B results in increased expression of METRNL mRNA

NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869

G

mex-3 RNA binding family member A

decreases expression

licochalcone B results in decreased expression of MEX3A mRNA

NCBI chr 2:173,990,098...173,999,567
Ensembl chr 2:173,989,856...173,997,377

G

mex-3 RNA binding family member B

increases expression

licochalcone B results in increased expression of MEX3B mRNA

NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354

G

mex-3 RNA binding family member D

increases expression

licochalcone B results in increased expression of MEX3D mRNA

NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096

G

milk fat globule EGF and factor V/VIII domain containing

increases expression

licochalcone B results in increased expression of MFGE8 mRNA

NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073

G

mitochondria-localized glutamic acid-rich protein

increases expression

licochalcone B results in increased expression of MGARP mRNA

NCBI chr 2:135,431,283...135,439,425
Ensembl chr 2:135,431,283...135,439,612

G

MICAL-like 2

increases expression

licochalcone B results in increased expression of MICALL2 mRNA

NCBI chr12:14,899,188...14,927,949
Ensembl chr12:14,899,157...14,927,946

G

microRNA 125b-1

decreases expression

licochalcone B results in decreased expression of MIR125B1 mRNA

NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052

G

microRNA 126a

decreases expression

licochalcone B results in decreased expression of MIR126 mRNA

NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180

G

microRNA 127

increases expression

licochalcone B results in increased expression of MIR127 mRNA

NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311

G

microRNA 143

increases expression

licochalcone B results in increased expression of MIR143 mRNA

NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110

G

microRNA 146a

increases expression

licochalcone B results in increased expression of MIR146A mRNA

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

G

microRNA 148a

decreases expression

licochalcone B results in decreased expression of MIR148A mRNA

NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858

G

microRNA 181b-1

decreases expression

licochalcone B results in decreased expression of MIR181B1 mRNA

NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797

G

microRNA 191

decreases expression

licochalcone B results in decreased expression of MIR191 mRNA

NCBI chr 8:109,264,098...109,264,188

G

microRNA 193a

increases expression

licochalcone B results in increased expression of MIR193A mRNA

NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454

G

microRNA 19a

increases expression

licochalcone B results in increased expression of MIR19A mRNA

NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993

G

microRNA 200a

increases expression

licochalcone B results in increased expression of MIR200A mRNA

NCBI chr 5:166,648,494...166,648,582

G

microRNA 206

increases expression

licochalcone B results in increased expression of MIR206 mRNA

NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332

G

microRNA 210

decreases expression

licochalcone B results in decreased expression of MIR210 mRNA

NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454

G

microRNA 222

decreases expression

licochalcone B results in decreased expression of MIR222 mRNA

NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006

G

microRNA 23b

decreases expression

licochalcone B results in decreased expression of MIR23B mRNA

NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763

G

microRNA 25

decreases expression

licochalcone B results in decreased expression of MIR25 mRNA

NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015

G

microRNA 27a

decreases expression

licochalcone B results in decreased expression of MIR27A mRNA

NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917

G

microRNA 27b

decreases expression

licochalcone B results in decreased expression of MIR27B mRNA

NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529

G

microRNA 296

decreases expression

licochalcone B results in decreased expression of MIR296 mRNA

NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915

G

microRNA 301a

decreases expression

licochalcone B results in decreased expression of MIR301A mRNA

NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435

G

microRNA 301b

increases expression

licochalcone B results in increased expression of MIR301B mRNA

NCBI chr11:83,879,816...83,879,893
Ensembl chr11:83,879,816...83,879,893

G

microRNA 30b

decreases expression

licochalcone B results in decreased expression of MIR30B mRNA

NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675

G

microRNA 30c-1

decreases expression

licochalcone B results in decreased expression of MIR30C1 mRNA

NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325

G

microRNA 30d

decreases expression

licochalcone B results in decreased expression of MIR30D mRNA

NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472

G

microRNA 322

decreases expression

licochalcone B results in decreased expression of MIR424 mRNA

NCBI chr X:132,806,594...132,806,688
Ensembl chr X:132,806,594...132,806,688

G

microRNA 33

decreases expression

licochalcone B results in decreased expression of MIR33A mRNA

NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923

G

microRNA 374b

decreases expression

licochalcone B results in decreased expression of MIR374B mRNA

NCBI chr X:68,591,732...68,591,799
Ensembl chr X:68,591,732...68,591,799

G

microRNA 451a

increases expression

licochalcone B results in increased expression of MIR451A mRNA

NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591

G

microRNA 484

decreases expression

licochalcone B results in decreased expression of MIR484 mRNA

NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760

G

microRNA 615

decreases expression

licochalcone B results in decreased expression of MIR615 mRNA

NCBI chr 7:134,151,887...134,151,978
Ensembl chr 7:134,151,887...134,151,978

G

microRNA 671

decreases expression

licochalcone B results in decreased expression of MIR671 mRNA

NCBI chr 4:10,580,747...10,580,827
Ensembl chr 4:10,580,738...10,580,835

G

microRNA 675

decreases expression

licochalcone B results in decreased expression of MIR675 mRNA

NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358

G

microRNA 760

decreases expression

licochalcone B results in decreased expression of MIR760 mRNA

NCBI chr 2:210,392,616...210,392,695
Ensembl chr 2:210,392,616...210,392,695

G

microRNA 874

decreases expression

licochalcone B results in decreased expression of MIR874 mRNA

NCBI chr17:6,620,649...6,620,724
Ensembl chr17:6,620,649...6,620,724

G

microRNA 92a-1

decreases expression

licochalcone B results in decreased expression of MIR92A1 mRNA

NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413

G

microRNA 96

increases expression

licochalcone B results in increased expression of MIR96 mRNA

NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516

G

microRNA let-7c-1

decreases expression

licochalcone B results in decreased expression of MIRLET7C mRNA

NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265

G

MKRN2 opposite strand

decreases expression

licochalcone B results in decreased expression of MKRN2OS mRNA

NCBI chr 4:148,644,489...148,653,396
Ensembl chr 4:148,644,609...148,652,712

G

MN1 proto-oncogene, transcriptional regulator

decreases expression

licochalcone B results in decreased expression of MN1 mRNA

NCBI chr12:45,181,794...45,220,959
Ensembl chr12:45,183,085...45,221,651

G

meiosis-specific nuclear structural 1

decreases expression

licochalcone B results in decreased expression of MNS1 mRNA

NCBI chr 8:73,148,877...73,169,570
Ensembl chr 8:73,148,877...73,176,925

G

megakaryocyte and platelet inhibitory receptor G6b

increases expression

licochalcone B results in increased expression of MPIG6B mRNA

NCBI chr20:3,757,396...3,761,024
Ensembl chr20:3,757,536...3,760,735

G

mitochondrial ribosomal protein L18

increases expression

licochalcone B results in increased expression of MRPL18 mRNA

NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987

G

mitochondrial ribosomal protein S24

increases expression

licochalcone B results in increased expression of MRPS24 mRNA

NCBI chr14:80,584,671...80,588,801
Ensembl chr14:80,584,673...80,588,871

G

myocardin related transcription factor B

decreases expression

licochalcone B results in decreased expression of MRTFB mRNA

NCBI chr10:1,116,315...1,278,106
Ensembl chr10:1,116,310...1,277,897

G

msh homeobox 1

increases expression

licochalcone B results in increased expression of MSX1 mRNA

NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966

G

mitochondrially encoded ATP synthase membrane subunit 8

decreases expression

licochalcone B results in decreased expression of ATP8 mRNA

NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961

G

mitochondrially encoded cytochrome c oxidase I

decreases expression

licochalcone B results in decreased expression of COX1 mRNA

NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

mitochondrially encoded cytochrome c oxidase III

decreases expression

licochalcone B results in decreased expression of COX3 mRNA

NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

decreases expression

licochalcone B results in decreased expression of ND2 mRNA

NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3

decreases expression

licochalcone B results in decreased expression of ND3 mRNA

NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4

decreases expression

licochalcone B results in decreased expression of ND4 mRNA

NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L

decreases expression

licochalcone B results in decreased expression of ND4L mRNA

NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

decreases expression

licochalcone B results in decreased expression of ND5 mRNA

NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

decreases expression

licochalcone B results in decreased expression of ND6 mRNA

NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061

G

mucin 20, cell surface associated

increases expression

licochalcone B results in increased expression of MUC20 mRNA

NCBI chr11:67,987,816...68,001,496
Ensembl chr11:67,987,800...68,001,495

G

mucin 6, oligomeric mucus/gel-forming

decreases expression

licochalcone B results in decreased expression of MUC6 mRNA

NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842

G

murinoglobulin 2

decreases expression

licochalcone B results in decreased expression of PZP mRNA

NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475

G

max dimerization protein 1

increases expression

licochalcone B results in increased expression of MXD1 mRNA

NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751

G

MYCL proto-oncogene, bHLH transcription factor

increases expression

licochalcone B results in increased expression of MYCL mRNA

NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582

G

myosin regulatory light chain interacting protein

increases expression

licochalcone B results in increased expression of MYLIP mRNA

NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295

G

myosin XVA

increases expression

licochalcone B results in increased expression of MYO15A mRNA

NCBI chr10:45,277,619...45,335,953
Ensembl chr10:45,278,737...45,335,340

G

myelin transcription factor 1-like

decreases expression

licochalcone B results in decreased expression of MYT1L mRNA

NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671

G

NEDD4 binding protein 2-like 1

increases expression

licochalcone B results in increased expression of N4BP2L1 mRNA

NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257

G

nuclear apoptosis inducing factor 1

increases expression

licochalcone B results in increased expression of NAIF1 mRNA

NCBI chr 3:15,741,239...15,747,672
Ensembl chr 3:15,742,919...15,747,669

G

nanos C2HC-type zinc finger 1

increases expression

licochalcone B results in increased expression of NANOS1 mRNA

NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730

G

NCCRP1, F-box associated domain containing

decreases expression

licochalcone B results in decreased expression of NCCRP1 mRNA

NCBI chr 1:83,835,083...83,838,620
Ensembl chr 1:83,835,083...83,838,676

G

NCK-associated protein 5-like

increases expression

licochalcone B results in increased expression of NCKAP5L mRNA

NCBI chr 7:130,553,683...130,591,886
Ensembl chr 7:130,555,368...130,591,857

G

N-terminal EF-hand calcium binding protein 1

increases expression

licochalcone B results in increased expression of NECAB1 mRNA

NCBI chr 5:28,357,859...28,578,642
Ensembl chr 5:28,357,859...28,578,642
Ensembl chr 5:28,357,859...28,578,642

G

neuraminidase 1

increases expression

licochalcone B results in increased expression of NEU1 mRNA

NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745

G

neuraminidase 4

decreases expression

licochalcone B results in decreased expression of NEU4 mRNA

NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576

G

neuralized E3 ubiquitin protein ligase 1B

decreases expression

licochalcone B results in decreased expression of NEURL1B mRNA

NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119

G

nuclear factor of activated T-cells 1

increases expression

licochalcone B results in increased expression of NFATC1 mRNA

NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028

G

NFKB inhibitor alpha

multiple interactions

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor delta

increases expression

licochalcone B results in increased expression of NFKBID mRNA

NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447

G

NFKB inhibitor zeta

increases expression

licochalcone B results in increased expression of NFKBIZ mRNA

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

G

nerve growth factor receptor

increases expression

licochalcone B results in increased expression of NGFR mRNA

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

nescient helix loop helix 1

increases expression

licochalcone B results in increased expression of NHLH1 mRNA

NCBI chr13:84,517,347...84,522,548
Ensembl chr13:84,517,289...84,525,094

G

niban apoptosis regulator 3

increases expression

licochalcone B results in increased expression of NIBAN3 mRNA

NCBI chr16:18,307,122...18,318,589
Ensembl chr16:18,307,221...18,318,585

G

nidogen 2

increases expression

licochalcone B results in increased expression of NID2 mRNA

NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843

G

NK2 homeobox 5

increases expression

licochalcone B results in increased expression of NKX2-5 mRNA

NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934

G

NK3 homeobox 1

increases expression

licochalcone B results in increased expression of NKX3-1 mRNA

NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441

G

NLR family, CARD domain containing 3

decreases expression

licochalcone B results in decreased expression of NLRC3 mRNA

NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398

G

neuromedin B

increases expression

licochalcone B results in increased expression of NMB mRNA

NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190

G

nicotinamide riboside kinase 2

increases expression

licochalcone B results in increased expression of NMRK2 mRNA

NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922

G

neuronatin

increases expression

licochalcone B results in increased expression of NNAT mRNA

NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834

G

nocturnin

increases expression

licochalcone B results in increased expression of NOCT mRNA

NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400

G

nitric oxide synthase 2

multiple interactions

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

notch receptor 1

increases expression

licochalcone B results in increased expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

notch receptor 4

increases expression

licochalcone B results in increased expression of NOTCH4 mRNA

NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465

G

neuropeptide Y receptor Y4

decreases expression

licochalcone B results in decreased expression of NPY4R mRNA

NCBI chr16:9,467,801...9,469,057
Ensembl chr16:9,467,801...9,469,057

G

nuclear receptor subfamily 1, group I, member 3

decreases expression

licochalcone B results in decreased expression of NR1I3 mRNA

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

Notch-regulated ankyrin repeat protein

increases expression

licochalcone B results in increased expression of NRARP mRNA

NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133

G

neuronal regeneration related protein

decreases expression

licochalcone B results in decreased expression of NREP mRNA

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

neurotensin receptor 1

decreases expression

licochalcone B results in decreased expression of NTSR1 mRNA

NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377

G

nudix hydrolase 12

decreases expression

licochalcone B results in decreased expression of NUDT12 mRNA

NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039

G

nuclear GTPase, germinal center associated

increases expression

licochalcone B results in increased expression of NUGGC mRNA

NCBI chr15:39,821,851...39,866,122
Ensembl chr15:39,821,855...39,866,122

G

nuclear RNA export factor 1

increases expression

licochalcone B results in increased expression of NXF1 mRNA

NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636

G

ornithine aminotransferase

increases expression

licochalcone B results in increased expression of OAT mRNA

NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682

G

oxidative stress responsive serine-rich 1

increases expression

licochalcone B results in increased expression of OSER1 mRNA

NCBI chr 3:152,066,975...152,085,180
Ensembl chr 3:152,066,975...152,085,149

G

oxidative stress induced growth inhibitor 1

increases expression

licochalcone B results in increased expression of OSGIN1 mRNA

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

odd-skipped related transciption factor 2

increases expression

licochalcone B results in increased expression of OSR2 mRNA

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

G

OTU deubiquitinase 5

increases expression

licochalcone B results in increased expression of OTUD5 mRNA

NCBI chr X:14,626,173...14,659,331
Ensembl chr X:14,626,164...14,659,573

G

OTU deubiquitinase with linear linkage specificity like

decreases expression

licochalcone B results in decreased expression of OTULINL mRNA

NCBI chr 2:78,405,994...78,433,860
Ensembl chr 2:78,408,593...78,433,838

G

pyrimidinergic receptor P2Y6

decreases expression

licochalcone B results in decreased expression of P2RY6 mRNA

NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808

G

poly(A) binding protein, cytoplasmic 4-like

decreases expression

licochalcone B results in decreased expression of PABPC4L mRNA

NCBI chr 2:129,807,755...129,809,745
Ensembl chr 2:129,807,755...129,809,745

G

peptidyl arginine deiminase 2

decreases expression

licochalcone B results in decreased expression of PADI2 mRNA

NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632

G

palmdelphin

decreases expression

licochalcone B results in decreased expression of PALMD mRNA

NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases cleavage

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [licochalcone B results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [licochalcone B results in increased expression of PARP1 protein]; TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of PARP1 protein]

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

poly (ADP-ribose) polymerase family, member 9

decreases expression

licochalcone B results in decreased expression of PARP9 mRNA

NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455

G

protocadherin beta 16

decreases expression

licochalcone B results in decreased expression of PCDHB16 mRNA

NCBI chr18:29,192,260...29,195,669
Ensembl chr18:29,192,124...29,200,539

G

protocadherin beta 19

decreases expression

licochalcone B results in decreased expression of PCDHB12 mRNA

NCBI chr18:29,204,838...29,207,646

G

protocadherin gamma subfamily A, 1

decreases expression

licochalcone B results in decreased expression of PCDHGA1 mRNA

NCBI chr18:29,487,404...29,667,865
Ensembl chr18:29,487,482...29,492,857
Ensembl chr18:29,487,482...29,492,857

G

protocadherin gamma subfamily A, 10

decreases expression

licochalcone B results in decreased expression of PCDHGA10 mRNA

NCBI chr18:29,574,693...29,667,865
Ensembl chr18:29,493,954...29,667,868

G

proprotein convertase subtilisin/kexin type 1

decreases expression

licochalcone B results in decreased expression of PCSK1 mRNA

NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434

G

phosphodiesterase 3A

decreases expression

licochalcone B results in decreased expression of PDE3A mRNA

NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274

G

platelet derived growth factor subunit A

increases expression

licochalcone B results in increased expression of PDGFA mRNA

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

platelet derived growth factor subunit B

decreases expression

licochalcone B results in decreased expression of PDGFB mRNA

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

proliferation and apoptosis adaptor protein 15

increases expression

licochalcone B results in increased expression of PEA15 mRNA

NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499

G

placental growth factor

increases expression

licochalcone B results in increased expression of PGF mRNA

NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685

G

PH domain containing endocytic trafficking adaptor 1

increases expression

licochalcone B results in increased expression of PHETA1 mRNA

NCBI chr12:34,711,831...34,717,601
Ensembl chr12:34,711,810...34,717,081

G

phosphorylase kinase catalytic subunit gamma 1

increases expression

licochalcone B results in increased expression of PHKG1 mRNA

NCBI chr12:26,838,822...26,854,547
Ensembl chr12:26,838,968...26,852,850

G

pleckstrin homology-like domain, family A, member 2

increases expression

licochalcone B results in increased expression of PHLDA2 mRNA

NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836

G

pleckstrin homology-like domain, family B, member 2

decreases expression

licochalcone B results in decreased expression of PHLDB2 mRNA

NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467

G

phytanoyl-CoA dioxygenase domain containing 1

increases expression

licochalcone B results in increased expression of PHYHD1 mRNA

NCBI chr 3:13,535,670...13,553,797
Ensembl chr 3:13,540,056...13,553,797

G

paired immunoglobin-like type 2 receptor alpha

increases expression

licochalcone B results in increased expression of PILRA mRNA

NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094

G

paired immunoglobin-like type 2 receptor beta 1

increases expression

licochalcone B results in increased expression of PILRB mRNA

NCBI chr12:18,516,161...18,525,375
Ensembl chr12:18,516,156...18,525,346

G

PITH domain containing 1

increases expression

licochalcone B results in increased expression of PITHD1 mRNA

NCBI chr 5:148,205,995...148,216,490
Ensembl chr 5:148,205,998...148,217,080

G

polycystin 1 like 1, transient receptor potential channel interacting

increases expression

licochalcone B results in increased expression of PKD1L1 mRNA

NCBI chr14:83,552,964...83,670,062
Ensembl chr14:83,545,469...83,638,498

G

polycystin 1 like 3, transient receptor potential channel interacting

increases expression

licochalcone B results in increased expression of PKD1L3 mRNA

NCBI chr19:37,585,564...37,650,083
Ensembl chr19:37,585,725...37,650,155

G

phospholipase A2 group 4A

decreases expression

licochalcone B results in decreased expression of PLA2G4A mRNA

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

G

PLAC8-like 1

increases expression

licochalcone B results in increased expression of PLAC8L1 mRNA

NCBI chr18:34,167,667...34,192,137
Ensembl chr18:34,168,864...34,190,800

G

phosphatidylinositol-specific phospholipase C, X domain containing 1

increases expression

licochalcone B results in increased expression of PLCXD1 mRNA

NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392

G

phospholipase D1

decreases expression

licochalcone B results in decreased expression of PLD1 mRNA

NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692

G

pleckstrin

increases expression

licochalcone B results in increased expression of PLEK mRNA

NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131

G

pleckstrin homology domain containing A2

decreases expression

licochalcone B results in decreased expression of PLEKHA2 mRNA

NCBI chr16:66,938,684...67,000,661
Ensembl chr16:66,939,109...66,999,395

G

pleckstrin homology and RhoGEF domain containing G6

decreases expression

licochalcone B results in decreased expression of PLEKHG6 mRNA

NCBI chr 4:158,163,443...158,182,628
Ensembl chr 4:158,162,969...158,182,271

G

pleckstrin homology domain containing O2

increases expression

licochalcone B results in increased expression of PLEKHO2 mRNA

NCBI chr 8:66,079,106...66,105,283
Ensembl chr 8:66,078,448...66,105,266

G

perilipin 2

increases expression

licochalcone B results in increased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

perilipin 5

increases expression

licochalcone B results in increased expression of PLIN5 mRNA

NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120

G

polo-like kinase 2

increases expression

licochalcone B results in increased expression of PLK2 mRNA

NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947

G

polo-like kinase 3

increases expression

licochalcone B results in increased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

polo-like kinase 5

increases expression

licochalcone B results in increased expression of PLK5 mRNA

NCBI chr 7:9,346,777...9,367,923
Ensembl chr 7:9,346,777...9,355,196

G

phospholipid phosphatase related 3

increases expression

licochalcone B results in increased expression of PLPPR3 mRNA

NCBI chr 7:9,831,162...9,842,434
Ensembl chr 7:9,831,162...9,845,296

G

plasmalemma vesicle associated protein

increases expression

licochalcone B results in increased expression of PLVAP mRNA

NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

licochalcone B results in increased expression of PMAIP1 mRNA

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

pregnancy up-regulated nonubiquitous CaM kinase

increases expression

licochalcone B results in increased expression of PNCK mRNA

NCBI chr X:151,369,406...151,373,508
Ensembl chr X:151,369,410...151,373,446

G

PARN like ribonuclease domain containing exonuclease 1

increases expression

licochalcone B results in increased expression of PNLDC1 mRNA

NCBI chr 1:47,843,224...47,861,675
Ensembl chr 1:47,843,224...47,861,674

G

patatin-like phospholipase domain containing 2

increases expression

licochalcone B results in increased expression of PNPLA2 mRNA

NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805

G

proline-rich nuclear receptor coactivator 1

increases expression

licochalcone B results in increased expression of PNRC1 mRNA

NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161

G

podocan-like 1

increases expression

licochalcone B results in increased expression of PODNL1 mRNA

NCBI chr19:24,027,261...24,033,867
Ensembl chr19:24,027,297...24,033,846

G

POTE ankyrin domain family, member F

decreases expression

licochalcone B results in decreased expression of POTEF mRNA

NCBI chr18:23,626,518...23,629,132
Ensembl chr 3:72,977,767...72,979,694

G

POU class 3 homeobox 1

increases expression

licochalcone B results in increased expression of POU3F1 mRNA

NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371

G

protein phosphatase with EF-hand domain 1

decreases expression

licochalcone B results in decreased expression of PPEF1 mRNA

NCBI chr X:33,994,503...34,151,704
Ensembl chr X:34,021,350...34,151,701

G

protein phosphatase 1, regulatory subunit 13B

increases expression

licochalcone B results in increased expression of PPP1R13B mRNA

NCBI chr 6:130,890,682...130,963,845
Ensembl chr 6:130,890,679...130,963,330

G

protein phosphatase 1, regulatory subunit 15A

increases expression

licochalcone B results in increased expression of PPP1R15A mRNA

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

protein phosphatase 1, regulatory subunit 27

increases expression

licochalcone B results in increased expression of PPP1R27 mRNA

NCBI chr10:105,828,364...105,829,533
Ensembl chr10:105,828,364...105,829,533

G

proline rich 18

increases expression

licochalcone B results in increased expression of PRR18 mRNA

NCBI chr 1:52,400,215...52,403,998
Ensembl chr 1:52,400,215...52,404,309

G

prostaglandin E receptor 1

increases expression

licochalcone B results in increased expression of PTGER1 mRNA

NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559

G

PX domain containing 1

increases expression

licochalcone B results in increased expression of PXDC1 mRNA

NCBI chr17:30,275,998...30,304,971
Ensembl chr17:30,276,377...30,304,973

G

glycogen phosphorylase, muscle associated

increases expression

licochalcone B results in increased expression of PYGM mRNA

NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368

G

RAB33A, member RAS oncogene family

increases expression

licochalcone B results in increased expression of RAB33A mRNA

NCBI chr X:127,694,219...127,706,378
Ensembl chr X:127,694,964...127,706,378

G

RAD9 checkpoint clamp component B

increases expression

licochalcone B results in increased expression of RAD9B mRNA

NCBI chr12:34,217,868...34,248,380
Ensembl chr12:34,218,024...34,248,372

G

Rap associating with DIL domain

increases expression

licochalcone B results in increased expression of RADIL mRNA

NCBI chr12:12,024,395...12,088,540
Ensembl chr12:12,024,395...12,088,540

G

retinoic acid receptor responder 2

decreases expression

licochalcone B results in decreased expression of RARRES2 mRNA

NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556

G

ras related dexamethasone induced 1

increases expression

licochalcone B results in increased expression of RASD1 mRNA

NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186

G

RAS-like, family 10, member A

increases expression

licochalcone B results in increased expression of RASL10A mRNA

NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468

G

RAS-like family 11 member A

increases expression

licochalcone B results in increased expression of RASL11A mRNA

NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576

G

Ras association domain family member 2

decreases expression

licochalcone B results in decreased expression of RASSF2 mRNA

NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431

G

Ras association domain family member 9

decreases expression

licochalcone B results in decreased expression of RASSF9 mRNA

NCBI chr 7:37,599,720...37,631,553
Ensembl chr 7:37,599,720...37,635,245

G

RNA binding fox-1 homolog 3

increases expression

licochalcone B results in increased expression of RBFOX3 mRNA

NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935

G

RNA binding motif protein 38

increases expression

licochalcone B results in increased expression of RBM38 mRNA

NCBI chr 3:161,801,577...161,814,381
Ensembl chr 3:161,801,577...161,814,381

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

increases expression

licochalcone B results in increased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

RELT-like 2

increases expression

licochalcone B results in increased expression of RELL2 mRNA

NCBI chr18:29,789,996...29,793,986
Ensembl chr18:29,790,415...29,793,986

G

RELT, TNF receptor

increases expression

licochalcone B results in increased expression of RELT mRNA

NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196

G

raftlin family member 2

increases expression

licochalcone B results in increased expression of RFTN2 mRNA

NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810

G

regulator of cell cycle

increases expression

licochalcone B results in increased expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

repulsive guidance molecule BMP co-receptor a

increases expression

licochalcone B results in increased expression of RGMA mRNA

NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918

G

regulator of G-protein signaling 16

increases expression

licochalcone B results in increased expression of RGS16 mRNA

NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857

G

regulator of G protein signaling 9 binding protein

decreases expression

licochalcone B results in decreased expression of RGS9BP mRNA

NCBI chr 1:88,249,438...88,250,151
Ensembl chr 1:88,249,438...88,250,151

G

RIB43A domain with coiled-coils 2

decreases expression

licochalcone B results in decreased expression of RIBC2 mRNA

NCBI chr 7:116,242,863...116,257,868
Ensembl chr 7:116,242,863...116,257,863

G

RIPOR family member 3

increases expression

licochalcone B results in increased expression of RIPOR3 mRNA

NCBI chr 3:156,687,253...156,760,524
Ensembl chr 3:156,687,517...156,715,061

G

Rho family GTPase 1

increases expression

licochalcone B results in increased expression of RND1 mRNA

NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399

G

ring finger protein 150

decreases expression

licochalcone B results in decreased expression of RNF150 mRNA

NCBI chr19:25,006,978...25,229,273
Ensembl chr19:25,006,611...25,228,678

G

ring finger protein 19B

increases expression

licochalcone B results in increased expression of RNF19B mRNA

NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380

G

ring finger protein 225

increases expression

licochalcone B results in increased expression of RNF225 mRNA

NCBI chr 1:73,543,598...73,546,269
Ensembl chr 1:73,543,598...73,546,269

G

ring finger protein 227

increases expression

licochalcone B results in increased expression of RNF227 mRNA

NCBI chr10:54,061,054...54,063,015
Ensembl chr10:54,059,947...54,063,010

G

ring finger protein 31

increases expression

licochalcone B results in increased expression of RNF31 mRNA

NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915

G

RAR-related orphan receptor B

decreases expression

licochalcone B results in decreased expression of RORB mRNA

NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390

G

RP1 like 1

decreases expression

licochalcone B results in decreased expression of RP1L1 mRNA

NCBI chr15:38,259,907...38,271,269
Ensembl chr15:38,259,928...38,270,316

G

ribosomal protein S6 kinase A2

decreases expression

licochalcone B results in decreased expression of RPS6KA2 mRNA

NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739

G

ribosomal protein S6 kinase B1

decreases phosphorylation

licochalcone B results in decreased phosphorylation of RPS6KB1 protein

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

licochalcone B results in increased expression of RRAD mRNA

NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417

G

radial spoke head 6 homolog A

increases expression

licochalcone B results in increased expression of RSPH6A mRNA

NCBI chr 1:78,700,801...78,720,444
Ensembl chr 1:78,700,814...78,720,431

G

arginine and serine rich protein 1

increases expression

licochalcone B results in increased expression of RSRP1 mRNA

NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523

G

RUNX family transcription factor 2

decreases expression

licochalcone B results in decreased expression of RUNX2 mRNA

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

S100 calcium binding protein A1

increases expression

licochalcone B results in increased expression of S100A1 mRNA

NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544

G

sterile alpha motif domain containing 5

decreases expression

licochalcone B results in decreased expression of SAMD5 mRNA

NCBI chr 1:4,041,547...4,090,909
Ensembl chr 1:3,677,784...4,091,120

G

sterile alpha motif domain containing 9

decreases expression

licochalcone B results in decreased expression of SAMD9 mRNA

NCBI chr 4:31,164,639...31,184,278
Ensembl chr 4:31,164,510...31,184,322

G

spermidine/spermine N1-acetyl transferase 1

increases expression

licochalcone B results in increased expression of SAT1 mRNA

NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813

G

stabilizer of axonemal microtubules 4

increases expression

licochalcone B results in increased expression of SAXO4 mRNA

NCBI chr 1:207,113,807...207,122,378
Ensembl chr 1:207,113,809...207,122,358

G

suprabasin

increases expression

licochalcone B results in increased expression of SBSN mRNA

NCBI chr 1:85,978,970...86,006,034
Ensembl chr 1:86,001,567...86,006,034

G

sodium voltage-gated channel beta subunit 3

decreases expression

licochalcone B results in decreased expression of SCN3B mRNA

NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868

G

scratch family transcriptional repressor 1

increases expression

licochalcone B results in increased expression of SCRT1 mRNA

NCBI chr 7:108,240,986...108,244,636
Ensembl chr 7:108,240,986...108,244,636

G

syndecan 4

increases expression

licochalcone B results in increased expression of SDC4 mRNA

NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580

G

syndecan binding protein 2

increases expression

licochalcone B results in increased expression of SDCBP2 mRNA

NCBI chr 3:140,060,746...140,098,063
Ensembl chr 3:140,070,540...140,098,057

G

semaphorin 4A

increases expression

licochalcone B results in increased expression of SEMA4A mRNA

NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442

G

semaphorin 5A

decreases expression

licochalcone B results in decreased expression of SEMA5A mRNA

NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084

G

SUMO specific peptidase 3

increases expression

licochalcone B results in increased expression of SENP3 mRNA

NCBI chr10:54,390,698...54,399,590
Ensembl chr10:54,390,694...54,399,593

G

serpin family B member 8

increases expression

licochalcone B results in increased expression of SERPINB8 mRNA

NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835

G

serpin family C member 1

increases expression

licochalcone B results in increased expression of SERPINC1 mRNA

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

G

SERTA domain containing 1

increases expression

licochalcone B results in increased expression of SERTAD1 mRNA

NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091

G

sestrin 2

increases expression

licochalcone B results in increased expression of SESN2 mRNA

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

G

sestrin 3

increases expression

licochalcone B results in increased expression of SESN3 mRNA

NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842

G

stratifin

increases expression

licochalcone B results in increased expression of SFN mRNA

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

secreted frizzled-related protein 5

increases expression

licochalcone B results in increased expression of SFRP5 mRNA

NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224

G

serum/glucocorticoid regulated kinase 2

increases expression

licochalcone B results in increased expression of SGK2 mRNA

NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480

G

small G protein signaling modulator 3

increases expression

licochalcone B results in increased expression of SGSM3 mRNA

NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:112,514,630...112,544,108

G

SH3 domain containing 21

increases expression

licochalcone B results in increased expression of SH3D21 mRNA

NCBI chr 5:138,429,180...138,444,540
Ensembl chr 5:138,429,180...138,444,407

G

SH3 and PX domains 2A

decreases expression

licochalcone B results in decreased expression of SH3PXD2A mRNA

NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166

G

sex hormone binding globulin

increases expression

licochalcone B results in increased expression of SHBG mRNA

NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057

G

sirtuin 7

increases expression

licochalcone B results in increased expression of SIRT7 mRNA

NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172

G

solute carrier family 12 member 7

decreases expression

licochalcone B results in decreased expression of SLC12A7 mRNA

NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302

G

solute carrier family 13 member 4

decreases expression

licochalcone B results in decreased expression of SLC13A4 mRNA

NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857

G

solute carrier family 16, member 11

increases expression

licochalcone B results in increased expression of SLC16A11 mRNA

NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915

G

solute carrier family 16, member 6

decreases expression

licochalcone B results in decreased expression of SLC16A6 mRNA

NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779

G

solute carrier family 16 member 7

decreases expression

licochalcone B results in decreased expression of SLC16A7 mRNA

NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994

G

solute carrier family 16, member 9

decreases expression

licochalcone B results in decreased expression of SLC16A9 mRNA

NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022

G

solute carrier family 17 member 7

increases expression

licochalcone B results in increased expression of SLC17A7 mRNA

NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588

G

solute carrier family 22 member 2

decreases expression

licochalcone B results in decreased expression of SLC22A2 mRNA

NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268

G

solute carrier family 25 member 25

increases expression

licochalcone B results in increased expression of SLC25A25 mRNA

NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216

G

solute carrier family 39 member 4

increases expression

licochalcone B results in increased expression of SLC39A4 mRNA

NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553

G

solute carrier family 44, member 4

increases expression

licochalcone B results in increased expression of SLC44A4 mRNA

NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215

G

solute carrier family 5 member 5

increases expression

licochalcone B results in increased expression of SLC5A5 mRNA

NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697

G

solute carrier family 6 member 13

increases expression

licochalcone B results in increased expression of SLC6A13 mRNA

NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152

G

solute carrier family 6 member 15

decreases expression

licochalcone B results in decreased expression of SLC6A15 mRNA

NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239

G

solute carrier family 7 member 8

decreases expression

licochalcone B results in decreased expression of SLC7A8 mRNA

NCBI chr15:28,183,013...28,242,717
Ensembl chr15:28,183,015...28,242,717

G

solute carrier family 9 member A1

increases expression

licochalcone B results in increased expression of SLC9A1 mRNA

NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624

G

SLIT and NTRK-like family, member 5

decreases expression

licochalcone B results in decreased expression of SLITRK5 mRNA

NCBI chr15:88,848,123...88,858,809
Ensembl chr15:88,847,535...88,856,836

G

SLIT and NTRK-like family, member 6

decreases expression

licochalcone B results in decreased expression of SLITRK6 mRNA

NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393

G

SMAD family member 7

increases expression

licochalcone B results in increased expression of SMAD7 mRNA

NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765

G

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`

decreases expression

licochalcone B results in decreased expression of SMARCAD1 mRNA

NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563

G

snail family transcriptional repressor 1

increases expression

licochalcone B results in increased expression of SNAI1 mRNA

NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969

G

suppressor of cytokine signaling 1

increases expression

licochalcone B results in increased expression of SOCS1 mRNA

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

suppressor of cytokine signaling 3

increases expression

licochalcone B results in increased expression of SOCS3 mRNA

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

sorbin and SH3 domain containing 1

increases expression

licochalcone B results in increased expression of SORBS1 mRNA

NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169

G

sorbin and SH3 domain containing 2

decreases expression

licochalcone B results in decreased expression of SORBS2 mRNA

NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514

G

sosondowah ankyrin repeat domain family member D

increases expression

licochalcone B results in increased expression of SOWAHD mRNA

NCBI chr X:116,292,030...116,293,660
Ensembl chr X:116,292,030...116,293,660

G

SRY-box transcription factor 17

increases expression

licochalcone B results in increased expression of SOX17 mRNA

NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228

G

SRY-box transcription factor 9

increases expression

licochalcone B results in increased expression of SOX9 mRNA

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

G

Sp6 transcription factor

increases expression

licochalcone B results in increased expression of SP6 mRNA

NCBI chr10:82,005,518...82,009,699
Ensembl chr10:82,005,294...82,011,013

G

sperm acrosome developmental regulator

increases expression

licochalcone B results in increased expression of SPACDR mRNA

NCBI chr12:18,930,608...18,936,787
Ensembl chr12:18,914,398...18,952,008

G

spermatogenesis associated 2-like

increases expression

licochalcone B results in increased expression of SPATA2L mRNA

NCBI chr19:51,269,078...51,273,605
Ensembl chr19:51,269,078...51,273,510

G

SPATA31 subfamily F member 1

increases expression

licochalcone B results in increased expression of SPATA31F1 mRNA

NCBI chr 5:57,065,743...57,071,880
Ensembl chr 5:57,065,747...57,071,738

G

SPATA31 subfamily H member 1

decreases expression

licochalcone B results in decreased expression of SPATA31H1 mRNA

NCBI chr 6:25,023,718...25,040,928

G

speedy/RINGO cell cycle regulator family member A

increases expression

licochalcone B results in increased expression of SPDYA mRNA

NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850

G

sphingosine kinase 1

increases expression

licochalcone B results in increased expression of SPHK1 mRNA

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

spindlin interactor and repressor of chromatin binding

increases expression

licochalcone B results in increased expression of SPINDOC mRNA

NCBI chr 1:204,541,647...204,565,109
Ensembl chr 1:204,542,335...204,564,144

G

spondin 1

increases expression

licochalcone B results in increased expression of SPON1 mRNA

NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226

G

sprouty RTK signaling antagonist 4

increases expression

licochalcone B results in increased expression of SPRY4 mRNA

NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004

G

splA/ryanodine receptor domain and SOCS box containing 1

increases expression

licochalcone B results in increased expression of SPSB1 mRNA

NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468

G

splA/ryanodine receptor domain and SOCS box containing 3

increases expression

licochalcone B results in increased expression of SPSB3 mRNA

NCBI chr10:13,907,175...13,912,841
Ensembl chr10:13,907,253...13,912,841

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serine and arginine rich splicing factor 12

increases expression

licochalcone B results in increased expression of SRSF12 mRNA

NCBI chr 5:47,606,526...47,631,509
Ensembl chr 5:47,606,285...47,629,778

G

somatostatin receptor 1

decreases expression

licochalcone B results in decreased expression of SSTR1 mRNA

NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802

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stanniocalcin 1

decreases expression

licochalcone B results in decreased expression of STC1 mRNA

NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264

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STEAP4 metalloreductase

decreases expression

licochalcone B results in decreased expression of STEAP4 mRNA

NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859

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syntaxin 11

increases expression

licochalcone B results in increased expression of STX11 mRNA

NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164

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synaptic vesicle glycoprotein 2a

increases expression

licochalcone B results in increased expression of SV2A mRNA

NCBI chr 2:183,741,489...183,757,290
Ensembl chr 2:183,741,547...183,756,927

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synaptic vesicle glycoprotein 2b

decreases expression

licochalcone B results in decreased expression of SV2B mRNA

NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479

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synapse differentiation inducing 1-like

increases expression

licochalcone B results in increased expression of SYNDIG1L mRNA

NCBI chr 6:104,318,096...104,344,989
Ensembl chr 6:104,323,424...104,344,891

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synaptotagmin 11

increases expression

licochalcone B results in increased expression of SYT11 mRNA

NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964

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synaptotagmin-like 5

decreases expression

licochalcone B results in decreased expression of SYTL5 mRNA

NCBI chr X:12,775,529...13,030,134
Ensembl chr X:12,788,698...13,030,175

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tumor-associated calcium signal transducer 2

increases expression

licochalcone B results in increased expression of TACSTD2 mRNA

NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650

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TAP binding protein-like

increases expression

licochalcone B results in increased expression of TAPBPL mRNA

NCBI chr 4:158,021,454...158,028,905

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taste 1 receptor member 1

increases expression

licochalcone B results in increased expression of TAS1R1 mRNA

NCBI chr 5:162,533,838...162,546,408
Ensembl chr 5:162,533,841...162,545,562

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Tax1 binding protein 3

increases expression

licochalcone B results in increased expression of TAX1BP3 mRNA

NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363

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T-box brain transcription factor 1

increases expression

licochalcone B results in increased expression of TBR1 mRNA

NCBI chr 3:46,350,237...46,368,397
Ensembl chr 3:46,351,213...46,361,041

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titin-cap

increases expression

licochalcone B results in increased expression of TCAP mRNA

NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887

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transcriptional and immune response regulator

decreases expression

licochalcone B results in decreased expression of TCIM mRNA

NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581

G

tektin 2

increases expression

licochalcone B results in increased expression of TEKT2 mRNA

NCBI chr 5:138,619,665...138,623,301
Ensembl chr 5:138,619,667...138,623,204

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terminal nucleotidyltransferase 5B

increases expression

licochalcone B results in increased expression of TENT5B mRNA

NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073

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terminal nucleotidyltransferase 5C

increases expression

licochalcone B results in increased expression of TENT5C mRNA

NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744

G

transferrin

increases expression

licochalcone B results in increased expression of TF mRNA

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

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transforming growth factor, beta 2

decreases expression

licochalcone B results in decreased expression of TGFB2 mRNA

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

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thrombospondin 1

increases expression

licochalcone B results in increased expression of THBS1 mRNA

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

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tigger transposable element derived 3

increases expression

licochalcone B results in increased expression of TIGD3 mRNA

NCBI chr 1:203,178,456...203,182,775
Ensembl chr 1:203,178,460...203,181,272

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transmembrane protein 178B

decreases expression

licochalcone B results in decreased expression of TMEM178B mRNA

NCBI chr 4:68,659,425...69,035,690
Ensembl chr 4:68,657,343...69,035,690

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transmembrane protein 191C

increases expression

licochalcone B results in increased expression of TMEM191C mRNA

NCBI chr11:83,726,155...83,728,926
Ensembl chr11:83,725,185...83,730,172

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transmembrane protein 61

decreases expression

licochalcone B results in decreased expression of TMEM61 mRNA

NCBI chr 5:121,266,799...121,276,426
Ensembl chr 5:121,266,799...121,276,057

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transmembrane protein 92

decreases expression

licochalcone B results in decreased expression of TMEM92 mRNA

NCBI chr10:79,749,242...79,760,807

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thiol methyltransferase 1A

decreases expression

licochalcone B results in decreased expression of TMT1A mRNA

NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154

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tumor necrosis factor

multiple interactions

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

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TNF receptor superfamily member 10b

increases expression

licochalcone B results in increased expression of TNFRSF10A protein

NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467

G

TNF receptor superfamily member 12A

increases expression

licochalcone B results in increased expression of TNFRSF12A mRNA

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNF superfamily member 15

decreases expression

licochalcone B results in decreased expression of TNFSF15 mRNA

NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228

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TNF superfamily member 9

increases expression

licochalcone B results in increased expression of TNFSF9 mRNA

NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345

G

tyrosine kinase, non-receptor, 1

increases expression

licochalcone B results in increased expression of TNK1 mRNA

NCBI chr10:54,571,396...54,580,547
Ensembl chr10:54,571,117...54,579,940

G

troponin C2, fast skeletal type

increases expression

licochalcone B results in increased expression of TNNC2 mRNA

NCBI chr 3:153,513,272...153,516,033
Ensembl chr 3:153,513,271...153,516,029

G

tensin 1

decreases expression

licochalcone B results in decreased expression of TNS1 mRNA

NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225

G

taperin

increases expression

licochalcone B results in increased expression of TPRN mRNA

NCBI chr 3:8,076,164...8,083,642
Ensembl chr 3:8,075,137...8,083,642

G

trafficking protein particle complex subunit 14

increases expression

licochalcone B results in increased expression of TRAPPC14 mRNA

NCBI chr12:17,262,748...17,267,093
Ensembl chr12:17,262,750...17,267,084

G

trafficking protein particle complex subunit 3L

decreases expression

licochalcone B results in decreased expression of TRAPPC3L mRNA

NCBI chr20:25,992,835...26,084,938
Ensembl chr20:25,967,502...26,078,989

G

tripartite motif-containing 26

increases expression

licochalcone B results in increased expression of TRIM26 mRNA

NCBI chr20:1,708,297...1,731,176
Ensembl chr20:1,709,788...1,731,120

G

tripartite motif-containing 36

increases expression

licochalcone B results in increased expression of TRIM36 mRNA

NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859

G

TMF1-regulated nuclear protein 1

increases expression

licochalcone B results in increased expression of TRNP1 mRNA

NCBI chr 5:145,706,427...145,713,279
Ensembl chr 5:145,706,094...145,713,272

G

TSC22 domain family, member 2

increases expression

licochalcone B results in increased expression of TSC22D2 mRNA

NCBI chr 2:142,646,778...142,697,977
Ensembl chr 2:142,644,744...142,693,606

G

tetraspanin 5

decreases expression

licochalcone B results in decreased expression of TSPAN5 mRNA

NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664

G

TSPO associated protein 1

increases expression

licochalcone B results in increased expression of TSPOAP1 mRNA

NCBI chr10:72,554,220...72,586,402
Ensembl chr10:72,560,980...72,586,412

G

tetratricopeptide repeat domain 23-like

increases expression

licochalcone B results in increased expression of TTC23L mRNA

NCBI chr 2:59,476,666...59,538,313
Ensembl chr 2:59,476,669...59,538,282

G

tetratricopeptide repeat domain 39B

decreases expression

licochalcone B results in decreased expression of TTC39B mRNA

NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270

G

tubulin, beta 2A class IIa

increases expression

licochalcone B results in increased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

tubulin, beta 3 class III

increases expression

licochalcone B results in increased expression of TUBB3 mRNA

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

G

tubulin, beta 4B class IVb

increases expression

licochalcone B results in increased expression of TUBB4B mRNA

NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296

G

TUB like protein 2

increases expression

licochalcone B results in increased expression of TULP2 mRNA

NCBI chr 1:95,962,496...95,999,775
Ensembl chr 1:95,962,496...96,000,628

G

thioredoxin interacting protein

decreases expression

licochalcone B results in decreased expression of TXNIP mRNA

NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886

G

UDP-N-acetylglucosamine pyrophosphorylase 1

increases expression

licochalcone B results in increased expression of UAP1 mRNA

NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469

G

ubiquitin-like modifier activating enzyme 7

increases expression

licochalcone B results in increased expression of UBA7 mRNA

NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099

G

UBA-like domain containing 2

increases expression

licochalcone B results in increased expression of UBALD2 mRNA

NCBI chr10:101,662,507...101,667,089
Ensembl chr10:101,658,127...101,667,061

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ubiquitin B

increases expression

licochalcone B results in increased expression of UBB mRNA

NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333

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ubiquitin C

increases expression

licochalcone B results in increased expression of UBC mRNA

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

ubiquitin-conjugating enzyme E2S

increases expression

licochalcone B results in increased expression of UBE2S mRNA

NCBI chr 1:69,028,853...69,032,914
Ensembl chr 1:69,028,750...69,032,914

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ubiquitin C-terminal hydrolase L1

increases expression

licochalcone B results in increased expression of UCHL1 mRNA

NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590

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uncoupling protein 3

increases expression

licochalcone B results in increased expression of UCP3 mRNA

NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762

G

UDP-glucose ceramide glucosyltransferase

increases expression

licochalcone B results in increased expression of UGCG mRNA

NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393

G

UL16 binding protein 1

increases expression

licochalcone B results in increased expression of ULBP1 mRNA

NCBI chr 1:1,694,255...1,716,160

G

unc-80 homolog, NALCN channel complex subunit

increases expression

licochalcone B results in increased expression of UNC80 mRNA

NCBI chr 9:68,011,940...68,190,135
Ensembl chr 9:68,011,728...68,187,659

G

uridine phosphorylase 1

increases expression

licochalcone B results in increased expression of UPP1 mRNA

NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462

G

vasorin

increases expression

licochalcone B results in increased expression of VASN mRNA

NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357

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vav guanine nucleotide exchange factor 1

increases expression

licochalcone B results in increased expression of VAV1 mRNA

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

G

vascular endothelial growth factor D

increases expression

licochalcone B results in increased expression of VEGFD mRNA

NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295

G

VGF nerve growth factor inducible

increases expression

licochalcone B results in increased expression of VGF mRNA

NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341

G

vitelline membrane outer layer 1 homolog

increases expression

licochalcone B results in increased expression of VMO1 mRNA

NCBI chr10:55,227,944...55,234,794
Ensembl chr10:55,227,944...55,229,289

G

V-set pre-B cell surrogate light chain 3

increases expression

licochalcone B results in increased expression of VPREB3 mRNA

NCBI chr20:12,717,421...12,718,785
Ensembl chr20:12,716,779...12,719,520

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von Willebrand factor A domain containing 3A

increases expression

licochalcone B results in increased expression of VWA3A mRNA

NCBI chr 1:175,293,782...175,355,588
Ensembl chr 1:175,293,873...175,355,602

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von Willebrand factor A domain containing 5B2

increases expression

licochalcone B results in increased expression of VWA5B2 mRNA

NCBI chr11:80,306,067...80,323,220
Ensembl chr11:80,306,350...80,323,220

G

WD repeat domain 38

increases expression