Licochalcone B - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	Licochalcone B	go back to main search page
Accession:	CHEBI:174733	browse the term
Synonyms:	related_synonym:	(E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
	xref:	CAS:58749-23-8; Chemspider:4477423; HMDB:HMDB0037320
	xref_mesh:	MESH:C541528
	xref:	lipidmaps:LMPK12120434
	chemrof_formula:	C16H14O5
	chemrof_smiles:	COc1c(/C=C/C(=O)c2ccc(O)cc2)ccc(O)c1O
	chemrof_inchikey:	DRDRYGIIYOPBBZ-XBXARRHUSA-N
	chemrof_inchi:	InChI=1S/C16H14O5/c1-21-16-11(5-9-14(19)15(16)20)4-8-13(18)10-2-6-12(17)7-3-10/h2-9,17,19-20H,1H3/b8-4+

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Genes (853)

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

decreases expression

EXP

licochalcone B results in decreased expression of ABCA1 mRNA

NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155

G

ATP binding cassette subfamily A member 10

increases expression

EXP

licochalcone B results in increased expression of ABCA10 mRNA

NCBI chr17:69,148,007...69,244,848
Ensembl chr17:69,147,214...69,244,846

G

ATP binding cassette subfamily A member 8

decreases expression

EXP

licochalcone B results in decreased expression of ABCA8 mRNA

NCBI chr17:68,867,289...68,955,392
Ensembl chr17:68,866,052...68,955,470

G

ATP binding cassette subfamily B member 4

increases expression

EXP

licochalcone B results in increased expression of ABCB4 mRNA

NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435

G

acetylcholinesterase (Yt blood group)

increases expression

EXP

licochalcone B results in increased expression of ACHE mRNA

NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,897,022

G

acyl-CoA synthetase bubblegum family member 1

increases expression

EXP

licochalcone B results in increased expression of ACSBG1 mRNA

NCBI chr15:78,167,468...78,234,565
Ensembl chr15:78,167,468...78,245,688

G

actin alpha 1, skeletal muscle

increases expression

EXP

licochalcone B results in increased expression of ACTA1 mRNA

NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,789

G

actinin alpha 3

increases expression

EXP

licochalcone B results in increased expression of ACTN3 mRNA

NCBI chr11:66,546,395...66,563,334
Ensembl chr11:66,546,395...66,563,334

G

ADAM metallopeptidase with thrombospondin type 1 motif 5

decreases expression

EXP

licochalcone B results in decreased expression of ADAMTS5 mRNA

NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088

G

ArfGAP with dual PH domains 1

increases expression

EXP

licochalcone B results in increased expression of ADAP1 mRNA

NCBI chr 7:897,900...955,407
Ensembl chr 7:897,900...955,407

G

adenosine deaminase tRNA specific 3

increases expression

EXP

licochalcone B results in increased expression of ADAT3 mRNA

NCBI chr19:1,905,399...1,913,447
Ensembl chr19:1,905,399...1,913,447

G

adhesion G protein-coupled receptor G3

decreases expression

EXP

licochalcone B results in decreased expression of ADGRG3 mRNA

NCBI chr16:57,665,629...57,689,378
Ensembl chr16:57,668,277...57,689,378

G

adhesion G protein-coupled receptor L2

decreases expression

EXP

licochalcone B results in decreased expression of ADGRL2 mRNA

NCBI chr 1:81,306,132...81,993,932
Ensembl chr 1:81,306,112...81,993,940

G

adrenomedullin

increases expression

EXP

licochalcone B results in increased expression of ADM mRNA

NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,303,392...10,307,397

G

adrenoceptor alpha 1D

increases expression

EXP

licochalcone B results in increased expression of ADRA1D mRNA

NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287

G

adrenoceptor alpha 2B

increases expression

EXP

licochalcone B results in increased expression of ADRA2B mRNA

NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571

G

adrenoceptor beta 2

increases expression

EXP

licochalcone B results in increased expression of ADRB2 mRNA

NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623

G

arylformamidase

increases expression

EXP

licochalcone B results in increased expression of AFMID mRNA

NCBI chr17:78,187,362...78,207,702
Ensembl chr17:78,187,330...78,207,703

G

amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

decreases expression

EXP

licochalcone B results in decreased expression of AGL mRNA

NCBI chr 1:99,849,258...99,924,023
Ensembl chr 1:99,849,777...99,924,024

G

A-kinase anchoring protein 5

decreases expression

EXP

licochalcone B results in decreased expression of AKAP5 mRNA

NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503

G

aldo-keto reductase family 1 member B10

increases expression

EXP

licochalcone B results in increased expression of AKR1B10 mRNA

NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412

G

aldehyde dehydrogenase 1 family member A1

increases expression

EXP

licochalcone B results in increased expression of ALDH1A1 mRNA

NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,670...73,080,442

G

ALG9 alpha-1,2-mannosyltransferase

decreases expression

EXP

licochalcone B results in decreased expression of ALG9 mRNA

NCBI chr11:111,768,025...111,871,581
Ensembl chr11:111,782,195...111,872,405

G

ALK and LTK ligand 2

increases expression

EXP

licochalcone B results in increased expression of ALKAL2 mRNA

NCBI chr 2:279,558...288,091
Ensembl chr 2:278,286...289,623

G

arachidonate 12-lipoxygenase, 12S type

increases expression

EXP

licochalcone B results in increased expression of ALOX12 mRNA

NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754

G

arachidonate epidermal lipoxygenase 3

increases expression

EXP

licochalcone B results in increased expression of ALOXE3 mRNA

NCBI chr17:8,095,900...8,118,916
Ensembl chr17:8,095,900...8,119,047

G

angiogenin

decreases expression

EXP

licochalcone B results in decreased expression of ANG mRNA

NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,682,950...20,698,971

G

ankyrin repeat domain 1

increases expression

EXP

licochalcone B results in increased expression of ANKRD1 mRNA

NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,092...90,921,091

G

adaptor related protein complex 3 subunit beta 2

increases expression

EXP

licochalcone B results in increased expression of AP3B2 mRNA

NCBI chr15:82,659,281...82,709,875
Ensembl chr15:82,659,281...82,710,112

G

adaptor related protein complex 5 subunit zeta 1

increases expression

EXP

licochalcone B results in increased expression of AP5Z1 mRNA

NCBI chr 7:4,775,623...4,794,397
Ensembl chr 7:4,775,615...4,794,397

G

amyloid beta precursor protein binding family B member 1

increases expression

EXP

licochalcone B results in increased expression of APBB1 mRNA

NCBI chr11:6,395,124...6,419,453
Ensembl chr11:6,395,111...6,419,453

G

apolipoprotein B receptor

decreases expression

EXP

licochalcone B results in decreased expression of APOBR mRNA

NCBI chr16:28,494,643...28,498,964
Ensembl chr16:28,494,639...28,498,964

G

apolipoprotein E

increases expression

EXP

licochalcone B results in increased expression of APOE mRNA

NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,903,787...44,909,396

G

activity regulated cytoskeleton associated protein

increases expression

EXP

licochalcone B results in increased expression of ARC mRNA

NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479

G

Rho guanine nucleotide exchange factor 33

increases expression

EXP

licochalcone B results in increased expression of ARHGEF33 mRNA

NCBI chr 2:38,889,875...38,975,454
Ensembl chr 2:38,889,875...38,975,454

G

ARF like GTPase 4C

increases expression

EXP

licochalcone B results in increased expression of ARL4C mRNA

NCBI chr 2:234,493,041...234,497,081
Ensembl chr 2:234,493,041...234,497,081

G

ARF like GTPase 4D

increases expression

EXP

licochalcone B results in increased expression of ARL4D mRNA

NCBI chr17:43,398,993...43,401,137
Ensembl chr17:43,398,150...43,401,137

G

ARF like GTPase 6 interacting protein 4

increases expression

EXP

licochalcone B results in increased expression of ARL6IP4 mRNA

NCBI chr12:122,980,233...122,982,909
Ensembl chr12:122,980,045...122,983,479

G

aryl hydrocarbon receptor nuclear translocator 2

decreases expression

EXP

licochalcone B results in decreased expression of ARNT2 mRNA

NCBI chr15:80,404,382...80,597,933
Ensembl chr15:80,404,315...80,597,937

G

actin related protein 2/3 complex inhibitor

decreases expression

EXP

licochalcone B results in decreased expression of ARPIN mRNA

NCBI chr15:89,895,006...89,912,952
Ensembl chr15:89,895,006...89,912,952

G

acid sensing ion channel subunit family member 4

increases expression

EXP

licochalcone B results in increased expression of ASIC4 mRNA

NCBI chr 2:219,507,093...219,538,772
Ensembl chr 2:219,514,170...219,538,772

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

EXP

licochalcone B results in increased expression of ASNS mRNA

NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542

G

ATCAY kinesin light chain interacting caytaxin

increases expression

EXP

licochalcone B results in increased expression of ATCAY mRNA

NCBI chr19:3,880,685...3,928,082
Ensembl chr19:3,879,864...3,928,082

G

activating transcription factor 3

increases expression

EXP

licochalcone B results in increased expression of ATF3 mRNA

NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777

G

autophagy related 9B

increases expression

EXP

licochalcone B results in increased expression of ATG9B mRNA

NCBI chr 7:151,012,209...151,024,499
Ensembl chr 7:151,012,209...151,024,499

G

ATM serine/threonine kinase

increases phosphorylation

EXP

licochalcone B results in increased phosphorylation of ATM protein

NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102

G

ATPase 13A4

increases expression

EXP

licochalcone B results in increased expression of ATP13A4 mRNA

NCBI chr 3:193,398,967...193,593,119
Ensembl chr 3:193,398,967...193,593,111

G

ATPase Na+/K+ transporting subunit alpha 3

increases expression

EXP

licochalcone B results in increased expression of ATP1A3 mRNA

NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497

G

ATPase H+ transporting V0 subunit c

increases expression

EXP

licochalcone B results in increased expression of ATP6V0C mRNA

NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,713...2,520,218

G

ATPase phospholipid transporting 9A (putative)

decreases expression

EXP

licochalcone B results in decreased expression of ATP9A mRNA

NCBI chr20:51,596,514...51,768,390
Ensembl chr20:51,596,514...51,768,390

G

aurora kinase C

increases expression

EXP

licochalcone B results in increased expression of AURKC mRNA

NCBI chr19:57,231,023...57,235,548
Ensembl chr19:57,231,009...57,235,551

G

azurocidin 1

increases expression

EXP

licochalcone B results in increased expression of AZU1 mRNA

NCBI chr19:827,837...832,018
Ensembl chr19:825,097...832,018

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

increases expression

EXP

licochalcone B results in increased expression of B3GNT4 mRNA

NCBI chr12:122,203,709...122,208,952
Ensembl chr12:122,203,681...122,208,952

G

beta-1,4-N-acetyl-galactosaminyltransferase 3

increases expression

EXP

licochalcone B results in increased expression of B4GALNT3 mRNA

NCBI chr12:459,939...563,509
Ensembl chr12:459,923...563,509

G

BAG cochaperone 3

increases expression

EXP

licochalcone B results in increased expression of BAG3 mRNA

NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,650,879...119,677,913

G

BAR/IMD domain containing adaptor protein 2

increases expression

EXP

licochalcone B results in increased expression of BAIAP2 mRNA

NCBI chr17:81,035,151...81,117,434
Ensembl chr17:81,035,122...81,117,434

G

BAI1 associated protein 3

increases expression

EXP

licochalcone B results in increased expression of BAIAP3 mRNA

NCBI chr16:1,333,645...1,349,439
Ensembl chr16:1,333,638...1,349,439

G

BMP and activin membrane bound inhibitor

increases expression

EXP

licochalcone B results in increased expression of BAMBI mRNA

NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932

G

BCL2 associated X, apoptosis regulator

increases expression

EXP

licochalcone B results in increased expression of BAX protein

NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798

G

BCL2 binding component 3

increases expression

EXP

licochalcone B results in increased expression of BBC3 mRNA

NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,233,019

G

BCL2 apoptosis regulator

decreases expression

EXP

licochalcone B results in decreased expression of BCL2 protein

NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128

G

brain expressed X-linked 2

increases expression

EXP

licochalcone B results in increased expression of BEX2 mRNA

NCBI chr X:103,309,346...103,310,990
Ensembl chr X:103,309,345...103,311,298

G

BICD family like cargo adaptor 2

increases expression

EXP

licochalcone B results in increased expression of BICDL2 mRNA

NCBI chr16:3,027,682...3,036,944
Ensembl chr16:3,027,682...3,036,993

G

BCL2 interacting killer

increases expression

EXP

licochalcone B results in increased expression of BIK mRNA

NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,748...43,129,712

G

baculoviral IAP repeat containing 5

decreases expression

EXP

licochalcone B results in decreased expression of BIRC5 protein

NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636

G

biliverdin reductase B

increases expression

EXP

licochalcone B results in increased expression of BLVRB mRNA

NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,826

G

BMP binding endothelial regulator

decreases expression

EXP

licochalcone B results in decreased expression of BMPER mRNA

NCBI chr 7:33,904,915...34,156,427
Ensembl chr 7:33,904,308...34,156,427

G

bisphosphoglycerate mutase

increases expression

EXP

licochalcone B results in increased expression of BPGM mRNA

NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816

G

BRMS1 transcriptional repressor and anoikis regulator

increases expression

EXP

licochalcone B results in increased expression of BRMS1 mRNA

NCBI chr11:66,337,339...66,345,104
Ensembl chr11:66,337,333...66,345,132

G

bone marrow stromal cell antigen 1

increases expression

EXP

licochalcone B results in increased expression of BST1 mRNA

NCBI chr 4:15,703,065...15,774,173
Ensembl chr 4:15,703,000...15,775,614

G

BTB domain containing 8

decreases expression

EXP

licochalcone B results in decreased expression of BTBD8 mRNA

NCBI chr 1:92,080,345...92,184,723
Ensembl chr 1:92,080,305...92,184,725

G

BTG anti-proliferation factor 2

increases expression

EXP

licochalcone B results in increased expression of BTG2 mRNA

NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602

G

B and T lymphocyte associated

increases expression

EXP

licochalcone B results in increased expression of BTLA mRNA

NCBI chr 3:112,463,966...112,499,624
Ensembl chr 3:112,461,067...112,499,668

G

butyrophilin subfamily 3 member A1

decreases expression

EXP

licochalcone B results in decreased expression of BTN3A1 mRNA

NCBI chr 6:26,402,275...26,415,208
Ensembl chr 6:26,402,237...26,415,216

G

chromosome 10 open reading frame 95

decreases expression

EXP

licochalcone B results in decreased expression of C10ORF95 mRNA

NCBI chr10:102,449,837...102,451,543
Ensembl chr10:102,449,837...102,451,543

G

chromosome 11 open reading frame 86

decreases expression

EXP

licochalcone B results in decreased expression of C11ORF86 mRNA

NCBI chr11:66,975,304...66,977,009
Ensembl chr11:66,975,277...66,977,009

G

chromosome 13 open reading frame 46

decreases expression

EXP

licochalcone B results in decreased expression of C13ORF46 mRNA

NCBI chr13:113,926,514...113,974,076
Ensembl chr13:113,953,705...113,974,076

G

complement C1q like 3

increases expression

EXP

licochalcone B results in increased expression of C1QL3 mRNA

NCBI chr10:16,513,734...16,521,879
Ensembl chr10:16,513,734...16,521,879

G

C1q and TNF related 4

increases expression

EXP

licochalcone B results in increased expression of C1QTNF4 mRNA

NCBI chr11:47,589,667...47,595,304
Ensembl chr11:47,589,666...47,595,642

G

complement C5a receptor 2

decreases expression

EXP

licochalcone B results in decreased expression of C5AR2 mRNA

NCBI chr19:47,332,175...47,347,329
Ensembl chr19:47,332,148...47,347,329

G

calcium binding protein 7

increases expression

EXP

licochalcone B results in increased expression of CABP7 mRNA

NCBI chr22:29,720,003...29,731,833
Ensembl chr22:29,720,003...29,731,833

G

calcium voltage-gated channel auxiliary subunit alpha2delta 2

increases expression

EXP

licochalcone B results in increased expression of CACNA2D2 mRNA

NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244

G

calcium voltage-gated channel auxiliary subunit beta 2

decreases expression

EXP

licochalcone B results in decreased expression of CACNB2 mRNA

NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557

G

calbindin 2

increases expression

EXP

licochalcone B results in increased expression of CALB2 mRNA

NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436

G

caspase recruitment domain family member 9

increases expression

EXP

licochalcone B results in increased expression of CARD9 mRNA

NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,683

G

calcium responsive transcription factor

decreases expression

EXP

licochalcone B results in decreased expression of CARF mRNA

NCBI chr 2:202,912,275...202,988,263
Ensembl chr 2:202,912,214...202,988,263

G

caspase 14

decreases expression

EXP

licochalcone B results in decreased expression of CASP14 mRNA

NCBI chr19:15,049,480...15,058,293
Ensembl chr19:15,049,480...15,058,293

G

caspase 3

increases activity

EXP

licochalcone B results in increased activity of CASP3 protein

NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,695...184,650,418

G

caspase 8

increases cleavage
multiple interactions

EXP

licochalcone B results in increased cleavage of CASP8 protein
TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of CASP8 protein]

NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836

G

Cas scaffold protein family member 4

increases expression

EXP

licochalcone B results in increased expression of CASS4 mRNA

NCBI chr20:56,412,036...56,460,382
Ensembl chr20:56,412,049...56,460,387

G

cation channel sperm associated auxiliary subunit gamma

increases expression

EXP

licochalcone B results in increased expression of CATSPERG mRNA

NCBI chr19:38,335,830...38,370,943
Ensembl chr19:38,335,775...38,370,943

G

CACN subunit beta associated regulatory protein

increases expression

EXP

licochalcone B results in increased expression of CBARP mRNA

NCBI chr19:1,228,287...1,238,502
Ensembl chr19:1,228,284...1,239,465

G

chromobox 4

increases expression

EXP

licochalcone B results in increased expression of CBX4 mRNA

NCBI chr17:79,833,156...79,839,440
Ensembl chr17:79,833,156...79,839,469

G

coiled-coil domain containing 13

increases expression

EXP

licochalcone B results in increased expression of CCDC13 mRNA

NCBI chr 3:42,704,118...42,773,253
Ensembl chr 3:42,705,756...42,773,253

G

coiled-coil domain containing 148

increases expression

EXP

licochalcone B results in increased expression of CCDC148 mRNA

NCBI chr 2:158,171,073...158,456,753
Ensembl chr 2:158,171,073...158,456,753

G

coiled-coil domain containing 194

increases expression

EXP

licochalcone B results in increased expression of CCDC194 mRNA

NCBI chr19:17,387,196...17,394,196
Ensembl chr19:17,387,196...17,394,196

G

coiled-coil domain containing 68

decreases expression

EXP

licochalcone B results in decreased expression of CCDC68 mRNA

NCBI chr18:54,901,509...54,959,461
Ensembl chr18:54,901,504...54,959,519

G

coiled-coil domain containing 74B

increases expression

EXP

licochalcone B results in increased expression of CCDC74B mRNA

NCBI chr 2:130,139,287...130,145,112
Ensembl chr 2:130,139,287...130,145,134

G

coiled-coil domain containing 9

increases expression

EXP

licochalcone B results in increased expression of CCDC9 mRNA

NCBI chr19:47,256,525...47,275,723
Ensembl chr19:47,255,980...47,274,055

G

CCM2 like scaffold protein

increases expression

EXP

licochalcone B results in increased expression of CCM2L mRNA

NCBI chr20:32,010,438...32,032,180
Ensembl chr20:32,010,408...32,032,185

G

cellular communication network factor 1

increases expression

EXP

licochalcone B results in increased expression of CCN1 mRNA

NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,756...85,584,589

G

cellular communication network factor 2

increases expression

EXP

licochalcone B results in increased expression of CCN2 mRNA

NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,456

G

cyclin A2

decreases expression

EXP

licochalcone B results in decreased expression of CCNA2 mRNA

NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,917

G

cyclin B1

decreases expression

EXP

licochalcone B results in decreased expression of CCNB1 protein

NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,004...69,178,372

G

cyclin E1

increases expression

EXP

licochalcone B results in increased expression of CCNE1 mRNA

NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,471...29,824,313

G

cyclin P

increases expression

EXP

licochalcone B results in increased expression of CCNP mRNA

NCBI chr19:40,222,208...40,226,689
Ensembl chr19:40,222,208...40,226,697

G

CD14 molecule

increases expression

EXP

licochalcone B results in increased expression of CD14 mRNA

NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700

G

CD247 molecule

increases expression

EXP

licochalcone B results in increased expression of CD247 mRNA

NCBI chr 1:167,430,640...167,518,529
Ensembl chr 1:167,425,027...167,518,640

G

CD27 molecule

increases expression

EXP

licochalcone B results in increased expression of CD27 mRNA

NCBI chr12:6,443,892...6,451,713
Ensembl chr12:6,444,941...6,451,718

G

CD4 molecule

increases expression

EXP

licochalcone B results in increased expression of CD4 mRNA

NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,807

G

CD79a molecule

increases expression

EXP

licochalcone B results in increased expression of CD79A mRNA

NCBI chr19:41,877,279...41,881,372
Ensembl chr19:41,877,279...41,881,372

G

cell division cycle 25A

decreases expression

EXP

licochalcone B results in decreased expression of CDC25A protein

NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417

G

cell division cycle 25B

decreases expression

EXP

licochalcone B results in decreased expression of CDC25B protein

NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,730

G

cell division cycle 34, ubiqiutin conjugating enzyme

increases expression

EXP

licochalcone B results in increased expression of CDC34 mRNA

NCBI chr19:531,760...542,087
Ensembl chr19:531,721...542,092

G

CDC42 effector protein 2

increases expression

EXP

licochalcone B results in increased expression of CDC42EP2 mRNA

NCBI chr11:65,314,866...65,322,417
Ensembl chr11:65,314,834...65,322,662

G

cadherin related 23

increases expression

EXP

licochalcone B results in increased expression of CDH23 mRNA

NCBI chr10:71,396,920...71,815,947
Ensembl chr10:71,396,920...71,815,947

G

cyclin dependent kinase 1

decreases expression
multiple interactions

EXP

licochalcone B results in decreased expression of CDK1 mRNA
licochalcone B results in decreased expression of and results in decreased phosphorylation of CDK1 protein

PMID:24384411 PMID:35948134

NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,312...60,796,236

G

cyclin dependent kinase 11A

increases expression

EXP

licochalcone B results in increased expression of CDK11A mRNA

NCBI chr 1:1,702,379...1,724,357
Ensembl chr 1:1,702,379...1,724,482

G

cyclin dependent kinase 2

decreases expression

EXP

licochalcone B results in decreased expression of CDK2 mRNA

NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789

G

cyclin dependent kinase 2 associated protein 2

increases expression

EXP

licochalcone B results in increased expression of CDK2AP2 mRNA

NCBI chr11:67,506,497...67,508,162
Ensembl chr11:67,506,490...67,508,701

G

cyclin dependent kinase 5 regulatory subunit 1

increases expression

EXP

licochalcone B results in increased expression of CDK5R1 mRNA

NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,156...32,491,253

G

cyclin dependent kinase 5 regulatory subunit 2

decreases expression

EXP

licochalcone B results in decreased expression of CDK5R2 mRNA

NCBI chr 2:218,959,666...218,962,155
Ensembl chr 2:218,959,666...218,962,155

G

cyclin dependent kinase inhibitor 1A

increases expression

EXP

licochalcone B results in increased expression of CDKN1A mRNA

NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,441...36,687,397

G

cyclin dependent kinase inhibitor 1B

increases expression

EXP

licochalcone B results in increased expression of CDKN1B protein

NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,373

G

cyclin dependent kinase inhibitor 1C

increases expression

EXP

licochalcone B results in increased expression of CDKN1C mRNA

NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775

G

cyclin dependent kinase inhibitor 2D

increases expression

EXP

licochalcone B results in increased expression of CDKN2D mRNA

NCBI chr19:10,566,460...10,568,979
Ensembl chr19:10,566,460...10,569,059

G

CUGBP Elav-like family member 5

increases expression

EXP

licochalcone B results in increased expression of CELF5 mRNA

NCBI chr19:3,224,661...3,297,076
Ensembl chr19:3,224,650...3,297,076

G

centromere protein E

decreases expression

EXP

licochalcone B results in decreased expression of CENPE mRNA

NCBI chr 4:103,105,811...103,198,343
Ensembl chr 4:103,105,349...103,198,463

G

cilia and flagella associated protein 141

increases expression

EXP

licochalcone B results in increased expression of CFAP141 mRNA

NCBI chr 1:154,199,085...154,206,333
Ensembl chr 1:154,199,085...154,206,333

G

cilia and flagella associated protein 184

increases expression

EXP

licochalcone B results in increased expression of CFAP184 mRNA

NCBI chr 4:7,040,849...7,043,001
Ensembl chr 4:7,040,849...7,043,001

G

cilia and flagella associated protein 20

increases expression

EXP

licochalcone B results in increased expression of CFAP20 mRNA

NCBI chr16:58,113,592...58,129,381
Ensembl chr16:58,113,588...58,129,429

G

cilia and flagella associated protein 43

increases expression

EXP

licochalcone B results in increased expression of CFAP43 mRNA

NCBI chr10:104,129,888...104,232,364
Ensembl chr10:104,129,888...104,232,364

G

cilia and flagella associated protein 99

increases expression

EXP

licochalcone B results in increased expression of CFAP99 mRNA

NCBI chr 4:2,418,955...2,463,002
Ensembl chr 4:2,418,955...2,463,003

G

complement factor properdin

increases expression

EXP

licochalcone B results in increased expression of CFP mRNA

NCBI chr X:47,623,282...47,630,305
Ensembl chr X:47,621,537...47,630,305

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

increases expression

EXP

licochalcone B results in increased expression of CHAC1 mRNA

NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512

G

coiled-coil-helix-coiled-coil-helix domain containing 7

increases expression

EXP

licochalcone B results in increased expression of CHCHD7 mRNA

NCBI chr 8:56,211,789...56,218,809
Ensembl chr 8:56,211,686...56,218,809

G

checkpoint kinase 2

increases phosphorylation

EXP

licochalcone B results in increased phosphorylation of CHEK2 protein

NCBI chr22:28,687,742...28,741,834
Ensembl chr22:28,687,738...28,742,422

G

cholinergic receptor muscarinic 3

decreases expression

EXP

licochalcone B results in decreased expression of CHRM3 mRNA

NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,513...239,915,452

G

cholinergic receptor muscarinic 4

increases expression

EXP

licochalcone B results in increased expression of CHRM4 mRNA

NCBI chr11:46,383,789...46,391,776
Ensembl chr11:46,383,589...46,391,990

G

cholinergic receptor nicotinic alpha 3 subunit

increases expression

EXP

licochalcone B results in increased expression of CHRNA3 mRNA

NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295

G

cholinergic receptor nicotinic alpha 7 subunit

increases expression

EXP

licochalcone B results in increased expression of CHRNA7 mRNA

NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018

G

cholinergic receptor nicotinic delta subunit

decreases expression

EXP

licochalcone B results in decreased expression of CHRND mRNA

NCBI chr 2:232,526,160...232,536,664
Ensembl chr 2:232,525,993...232,536,667

G

cholinergic receptor nicotinic gamma subunit

decreases expression

EXP

licochalcone B results in decreased expression of CHRNG mRNA

NCBI chr 2:232,539,692...232,548,115
Ensembl chr 2:232,539,692...232,548,115

G

ciliary microtubule inner protein 2A

increases expression

EXP

licochalcone B results in increased expression of CIMIP2A mRNA

NCBI chr 9:137,243,599...137,255,122
Ensembl chr 9:137,243,584...137,247,770

G

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

increases expression

EXP

licochalcone B results in increased expression of CITED2 mRNA

NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,375,909

G

CDC28 protein kinase regulatory subunit 2

increases expression

EXP

licochalcone B results in increased expression of CKS2 mRNA

NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,155...89,316,715

G

claudin 19

increases expression

EXP

licochalcone B results in increased expression of CLDN19 mRNA

NCBI chr 1:42,733,093...42,740,236
Ensembl chr 1:42,733,093...42,740,254

G

claudin 6

increases expression

EXP

licochalcone B results in increased expression of CLDN6 mRNA

NCBI chr16:3,014,712...3,018,183
Ensembl chr16:3,014,705...3,020,071

G

claudin 9

increases expression

EXP

licochalcone B results in increased expression of CLDN9 mRNA

NCBI chr16:3,012,923...3,014,505
Ensembl chr16:3,012,923...3,014,505

G

clusterin

increases expression

EXP

licochalcone B results in increased expression of CLU mRNA

NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,615,056

G

cornichon family AMPA receptor auxiliary protein 3

increases expression

EXP

licochalcone B results in increased expression of CNIH3 mRNA

NCBI chr 1:224,434,640...224,740,554
Ensembl chr 1:224,434,660...224,740,559

G

cyclin and CBS domain divalent metal cation transport mediator 4

increases expression

EXP

licochalcone B results in increased expression of CNNM4 mRNA

NCBI chr 2:96,760,902...96,811,874
Ensembl chr 2:96,760,898...96,811,888

G

contactin 2

increases expression

EXP

licochalcone B results in increased expression of CNTN2 mRNA

NCBI chr 1:205,042,949...205,078,289
Ensembl chr 1:205,042,937...205,078,289

G

collagen type VI alpha 2 chain

increases expression

EXP

licochalcone B results in increased expression of COL6A2 mRNA

NCBI chr21:46,098,112...46,132,848
Ensembl chr21:46,096,722...46,132,851

G

cytochrome c oxidase subunit 8C

increases expression

EXP

licochalcone B results in increased expression of COX8C mRNA

NCBI chr14:93,347,182...93,348,356
Ensembl chr14:93,347,182...93,348,356

G

complexin 2

increases expression

EXP

licochalcone B results in increased expression of CPLX2 mRNA

NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,306...175,884,022

G

carbamoyl-phosphate synthase 1

decreases expression

EXP

licochalcone B results in decreased expression of CPS1 mRNA

NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107

G

cysteine rich secretory protein LCCL domain containing 1

decreases expression

EXP

licochalcone B results in decreased expression of CRISPLD1 mRNA

NCBI chr 8:74,984,505...75,034,558
Ensembl chr 8:74,984,502...75,034,558

G

cysteine rich secretory protein LCCL domain containing 2

increases expression

EXP

licochalcone B results in increased expression of CRISPLD2 mRNA

NCBI chr16:84,819,985...84,909,508
Ensembl chr16:84,819,981...84,920,768

G

crystallin beta A1

increases expression

EXP

licochalcone B results in increased expression of CRYBA1 mRNA

NCBI chr17:29,246,859...29,254,494
Ensembl chr17:29,246,859...29,254,494

G

crystallin beta-gamma domain containing 1

decreases expression

EXP

licochalcone B results in decreased expression of CRYBG1 mRNA

NCBI chr 6:106,360,717...106,572,017
Ensembl chr 6:106,360,717...106,572,017

G

crystallin mu

increases expression

EXP

licochalcone B results in increased expression of CRYM mRNA

NCBI chr16:21,258,521...21,303,062
Ensembl chr16:21,238,874...21,303,083

G

cysteine and serine rich nuclear protein 1

increases expression

EXP

licochalcone B results in increased expression of CSRNP1 mRNA

NCBI chr 3:39,141,855...39,154,641
Ensembl chr 3:39,141,854...39,154,852

G

cysteine and serine rich nuclear protein 2

increases expression

EXP

licochalcone B results in increased expression of CSRNP2 mRNA

NCBI chr12:51,061,205...51,083,596
Ensembl chr12:51,061,205...51,083,664

G

cysteine and glycine rich protein 2

increases expression

EXP

licochalcone B results in increased expression of CSRP2 mRNA

NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,703...76,879,638

G

CTAGE family member 4

decreases expression

EXP

licochalcone B results in decreased expression of CTAGE4 mRNA

NCBI chr 7:144,183,466...144,186,080
Ensembl chr 7:144,183,466...144,186,080

G

chymotrypsin C

increases expression

EXP

licochalcone B results in increased expression of CTRC mRNA

NCBI chr 1:15,438,443...15,449,242
Ensembl chr 1:15,438,442...15,449,242

G

C-X-C motif chemokine ligand 8

decreases expression

EXP

licochalcone B results in decreased expression of CXCL8 mRNA

NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,747,379

G

CXXC finger protein 4

decreases expression

EXP

licochalcone B results in decreased expression of CXXC4 mRNA

NCBI chr 4:104,468,308...104,494,894
Ensembl chr 4:104,468,308...104,494,901

G

cytoglobin

decreases expression

EXP

licochalcone B results in decreased expression of CYGB mRNA

NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175

G

cytochrome P450 family 27 subfamily A member 1

increases expression

EXP

licochalcone B results in increased expression of CYP27A1 mRNA

NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,738...218,815,293

G

dishevelled binding antagonist of beta catenin 3

increases expression

EXP

licochalcone B results in increased expression of DACT3 mRNA

NCBI chr19:46,647,551...46,661,182
Ensembl chr19:46,647,551...46,661,182

G

DDB1 and CUL4 associated factor 4 like 1

increases expression

EXP

licochalcone B results in increased expression of DCAF4L1 mRNA

NCBI chr 4:41,981,756...41,986,465
Ensembl chr 4:41,981,756...41,986,465

G

dicarbonyl and L-xylulose reductase

increases expression

EXP

licochalcone B results in increased expression of DCXR mRNA

NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,776

G

DNA damage inducible transcript 3

increases expression

EXP

licochalcone B results in increased expression of DDIT3 mRNA; licochalcone B results in increased expression of DDIT3 protein

PMID:33647349 PMID:35948134

NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737

G

discoidin domain receptor tyrosine kinase 2

increases expression

EXP

licochalcone B results in increased expression of DDR2 mRNA

NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,630,863...162,787,405

G

DExD/H-box helicase 60

decreases expression

EXP

licochalcone B results in decreased expression of DDX60 mRNA

NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883

G

death effector domain containing 2

increases expression

EXP

licochalcone B results in increased expression of DEDD2 mRNA

NCBI chr19:42,198,598...42,220,134
Ensembl chr19:42,198,593...42,220,140

G

diacylglycerol O-acyltransferase 1

increases expression

EXP

licochalcone B results in increased expression of DGAT1 mRNA

NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910

G

dihydrodiol dehydrogenase

increases expression

EXP

licochalcone B results in increased expression of DHDH mRNA

NCBI chr19:48,932,795...48,944,969
Ensembl chr19:48,933,699...48,944,969

G

dihydrofolate reductase 2

decreases expression

EXP

licochalcone B results in decreased expression of DHFR2 mRNA

NCBI chr 3:94,057,922...94,063,320
Ensembl chr 3:94,047,836...94,063,389

G

DExH-box helicase 58

increases expression

EXP

licochalcone B results in increased expression of DHX58 mRNA

NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,733

G

iodothyronine deiodinase 2

decreases expression

EXP

licochalcone B results in decreased expression of DIO2 mRNA

NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757

G

iodothyronine deiodinase 3

increases expression

EXP

licochalcone B results in increased expression of DIO3 mRNA

NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452

G

dispatched RND transporter family member 3

increases expression

EXP

licochalcone B results in increased expression of DISP3 mRNA

NCBI chr 1:11,479,155...11,537,551
Ensembl chr 1:11,478,905...11,537,583

G

DIX domain containing 1

decreases expression

EXP

licochalcone B results in decreased expression of DIXDC1 mRNA

NCBI chr11:111,927,315...112,022,653
Ensembl chr11:111,927,144...112,022,653

G

discs large MAGUK scaffold protein 3

decreases expression

EXP

licochalcone B results in decreased expression of DLG3 mRNA

NCBI chr X:70,444,835...70,505,490
Ensembl chr X:70,444,835...70,505,490

G

delta like canonical Notch ligand 4

increases expression

EXP

licochalcone B results in increased expression of DLL4 mRNA

NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,338...40,939,078

G

distal-less homeobox 2

increases expression

EXP

licochalcone B results in increased expression of DLX2 mRNA

NCBI chr 2:172,099,438...172,102,900
Ensembl chr 2:172,099,438...172,102,900

G

deleted in malignant brain tumors 1

decreases expression

EXP

licochalcone B results in decreased expression of DMBT1 mRNA

NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,643...122,643,740

G

dynein axonemal heavy chain 3

increases expression

EXP

licochalcone B results in increased expression of DNAH3 mRNA

NCBI chr16:20,933,111...21,159,459
Ensembl chr16:20,933,111...21,159,441

G

DnaJ heat shock protein family (Hsp40) member A4

increases expression

EXP

licochalcone B results in increased expression of DNAJA4 mRNA

NCBI chr15:78,264,145...78,282,191
Ensembl chr15:78,264,086...78,282,196

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

EXP

licochalcone B results in increased expression of DNAJB1 mRNA

NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391

G

DnaJ heat shock protein family (Hsp40) member C28

decreases expression

EXP

licochalcone B results in decreased expression of DNAJC28 mRNA

NCBI chr21:33,488,055...33,491,716
Ensembl chr21:33,486,096...33,491,749

G

dedicator of cytokinesis 3

increases expression

EXP

licochalcone B results in increased expression of DOCK3 mRNA

NCBI chr 3:50,674,927...51,384,198
Ensembl chr 3:50,674,927...51,384,198

G

DR1 associated protein 1

increases expression

EXP

licochalcone B results in increased expression of DRAP1 mRNA

NCBI chr11:65,919,426...65,921,563
Ensembl chr11:65,919,274...65,921,563

G

dynein regulatory complex subunit 1

increases expression

EXP

licochalcone B results in increased expression of DRC1 mRNA

NCBI chr 2:26,401,920...26,456,711
Ensembl chr 2:26,401,920...26,456,717

G

deltex E3 ubiquitin ligase 3L

decreases expression

EXP

licochalcone B results in decreased expression of DTX3L mRNA

NCBI chr 3:122,564,338...122,575,203
Ensembl chr 3:122,564,338...122,575,203

G

dual specificity phosphatase 2

increases expression

EXP

licochalcone B results in increased expression of DUSP2 mRNA

NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,166...96,145,440

G

dual specificity phosphatase 5

increases expression

EXP

licochalcone B results in increased expression of DUSP5 mRNA

NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,541

G

dual specificity phosphatase 7

increases expression

EXP

licochalcone B results in increased expression of DUSP7 mRNA

NCBI chr 3:52,048,919...52,056,571
Ensembl chr 3:52,048,919...52,056,571

G

epididymal protein 13

decreases expression

EXP

licochalcone B results in decreased expression of EDDM13 mRNA

NCBI chr19:56,272,748...56,310,454
Ensembl chr19:56,272,748...56,310,454

G

endothelin receptor type A

decreases expression

EXP

licochalcone B results in decreased expression of EDNRA mRNA

NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954

G

estrogen-induced osteoclastogenesis regulator 1

increases expression

EXP

licochalcone B results in increased expression of EEIG1 mRNA

NCBI chr 9:127,940,582...127,980,989
Ensembl chr 9:127,940,582...127,981,068

G

ephrin B2

increases expression

EXP

licochalcone B results in increased expression of EFNB2 mRNA

NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662

G

ephrin B3

increases expression

EXP

licochalcone B results in increased expression of EFNB3 mRNA

NCBI chr17:7,705,202...7,711,372
Ensembl chr17:7,705,202...7,711,372

G

EGF like domain multiple 8

decreases expression

EXP

licochalcone B results in decreased expression of EGFL8 mRNA

NCBI chr 6:32,164,595...32,168,281
Ensembl chr 6:32,163,918...32,168,453

G

early growth response 1

increases expression

EXP

licochalcone B results in increased expression of EGR1 mRNA

NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303

G

early growth response 3

increases expression

EXP

licochalcone B results in increased expression of EGR3 mRNA

NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480

G

EH domain containing 1

increases expression

EXP

licochalcone B results in increased expression of EHD1 mRNA

NCBI chr11:64,851,642...64,879,693
Ensembl chr11:64,851,642...64,888,372

G

ETS homologous factor

decreases expression

EXP

licochalcone B results in decreased expression of EHF mRNA

NCBI chr11:34,621,093...34,663,288
Ensembl chr11:34,617,044...34,663,386

G

eukaryotic translation initiation factor 2 alpha kinase 3

decreases expression

EXP

licochalcone B results in decreased expression of EIF2AK3 protein

NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518

G

eukaryotic translation initiation factor 4A1

increases expression

EXP

licochalcone B results in increased expression of EIF4A1 mRNA

NCBI chr17:7,572,825...7,579,006
Ensembl chr17:7,572,760...7,579,006

G

eukaryotic translation initiation factor 4A3

increases expression

EXP

licochalcone B results in increased expression of EIF4A3 mRNA

NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151

G

ER membrane protein complex subunit 9

increases expression

EXP

licochalcone B results in increased expression of EMC9 mRNA

NCBI chr14:24,138,965...24,141,591
Ensembl chr14:24,138,958...24,142,023

G

endo-beta-N-acetylglucosaminidase

increases expression

EXP

licochalcone B results in increased expression of ENGASE mRNA

NCBI chr17:79,074,824...79,088,599
Ensembl chr17:79,074,824...79,088,599

G

EPH receptor A2

increases expression

EXP

licochalcone B results in increased expression of EPHA2 mRNA

NCBI chr 1:16,124,337...16,156,069
Ensembl chr 1:16,124,337...16,156,069

G

EPH receptor A3

decreases expression

EXP

licochalcone B results in decreased expression of EPHA3 mRNA

NCBI chr 3:89,107,621...89,482,134
Ensembl chr 3:89,107,522...89,482,437

G

epiplakin 1

increases expression

EXP

licochalcone B results in increased expression of EPPK1 mRNA

NCBI chr 8:143,857,324...143,879,194
Ensembl chr 8:143,857,324...143,878,467

G

ES cell expressed Ras

increases expression

EXP

licochalcone B results in increased expression of ERAS mRNA

NCBI chr X:48,826,513...48,829,869
Ensembl chr X:48,826,513...48,830,138

G

ETS2 repressor factor

increases expression

EXP

licochalcone B results in increased expression of ERF mRNA

NCBI chr19:42,247,569...42,255,128
Ensembl chr19:42,247,569...42,255,131

G

ER lipid raft associated 2

decreases expression

EXP

licochalcone B results in decreased expression of ERLIN2 mRNA

NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422

G

espin

increases expression

EXP

licochalcone B results in increased expression of ESPN mRNA

NCBI chr 1:6,424,776...6,461,370
Ensembl chr 1:6,424,776...6,461,367

G

ETS variant transcription factor 7

increases expression

EXP

licochalcone B results in increased expression of ETV7 mRNA

NCBI chr 6:36,354,088...36,387,669
Ensembl chr 6:36,354,091...36,387,800

G

eva-1 homolog B

increases expression

EXP

licochalcone B results in increased expression of EVA1B mRNA

NCBI chr 1:36,322,030...36,324,154
Ensembl chr 1:36,322,030...36,324,154

G

exocyst complex component 3 like 2

increases expression

EXP

licochalcone B results in increased expression of EXOC3L2 mRNA

NCBI chr19:45,212,370...45,245,407
Ensembl chr19:45,212,370...45,245,407

G

eyes shut homolog

decreases expression

EXP

licochalcone B results in decreased expression of EYS mRNA

NCBI chr 6:63,719,980...65,707,226
Ensembl chr 6:63,719,980...65,707,226

G

coagulation factor II thrombin receptor

decreases expression

EXP

licochalcone B results in decreased expression of F2R mRNA

NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770

G

family with sequence similarity 117 member A

increases expression

EXP

licochalcone B results in increased expression of FAM117A mRNA

NCBI chr17:49,710,332...49,789,110
Ensembl chr17:49,710,332...49,789,180

G

family with sequence similarity 153 member A

increases expression

EXP

licochalcone B results in increased expression of FAM153A mRNA

NCBI chr 5:177,694,247...177,783,425
Ensembl chr 5:177,707,981...177,784,435

G

family with sequence similarity 222 member A

increases expression

EXP

licochalcone B results in increased expression of FAM222A mRNA

NCBI chr12:109,713,825...109,770,495
Ensembl chr12:109,713,825...109,770,495

G

family with sequence similarity 228 member B

increases expression

EXP

licochalcone B results in increased expression of FAM228B mRNA

NCBI chr 2:24,076,833...24,169,638
Ensembl chr 2:24,076,526...24,169,642

G

family with sequence similarity 43 member A

increases expression

EXP

licochalcone B results in increased expression of FAM43A mRNA

NCBI chr 3:194,685,883...194,689,037
Ensembl chr 3:194,685,883...194,689,037

G

family with sequence similarity 78 member A

decreases expression

EXP

licochalcone B results in decreased expression of FAM78A mRNA

NCBI chr 9:131,258,078...131,281,045
Ensembl chr 9:131,258,076...131,277,365

G

family with sequence similarity 89 member B

increases expression

EXP

licochalcone B results in increased expression of FAM89B mRNA

NCBI chr11:65,572,538...65,574,190
Ensembl chr11:65,572,349...65,574,198

G

family with sequence similarity 90 member A1

increases expression

EXP

licochalcone B results in increased expression of FAM90A1 mRNA

NCBI chr12:8,221,260...8,227,618
Ensembl chr12:8,221,260...8,227,621

G

fibrillarin like 1

increases expression

EXP

licochalcone B results in increased expression of FBLL1 mRNA

NCBI chr 5:168,529,305...168,530,634
Ensembl chr 5:168,529,305...168,530,634

G

F-box protein 32

increases expression

EXP

licochalcone B results in increased expression of FBXO32 mRNA

NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,273

G

Fc gamma binding protein

increases expression

EXP

licochalcone B results in increased expression of FCGBP mRNA

NCBI chr19:39,863,323...39,934,634
Ensembl chr19:39,863,323...39,934,626

G

Fc gamma receptor Ia

increases expression

EXP

licochalcone B results in increased expression of FCGR1A mRNA

NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,650...149,792,526

G

fer-1 like family member 5

increases expression

EXP

licochalcone B results in increased expression of FER1L5 mRNA

NCBI chr 2:96,642,764...96,704,883
Ensembl chr 2:96,642,737...96,704,887

G

fibroblast growth factor 18

increases expression

EXP

licochalcone B results in increased expression of FGF18 mRNA

NCBI chr 5:171,419,647...171,457,626
Ensembl chr 5:171,419,645...171,457,626

G

fibroblast growth factor 22

increases expression

EXP

licochalcone B results in increased expression of FGF22 mRNA

NCBI chr19:639,879...644,373
Ensembl chr19:639,879...644,373

G

fibroblast growth factor receptor 3

increases expression

EXP

licochalcone B results in increased expression of FGFR3 mRNA

NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,286...1,808,873

G

fat storage inducing transmembrane protein 1

increases expression

EXP

licochalcone B results in increased expression of FITM1 mRNA

NCBI chr14:24,130,659...24,132,847
Ensembl chr14:24,130,659...24,132,849

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

ISO
EXP

licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of FOS protein]
licochalcone B results in increased expression of FOS mRNA

PMID:25451593 PMID:33647349

NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

licochalcone B results in increased expression of FOSB mRNA

NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179

G

FOS like 1, AP-1 transcription factor subunit

increases expression

EXP

licochalcone B results in increased expression of FOSL1 mRNA

NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573

G

forkhead box A3

increases expression

EXP

licochalcone B results in increased expression of FOXA3 mRNA

NCBI chr19:45,864,326...45,873,797
Ensembl chr19:45,863,989...45,873,798

G

forkhead box D1

increases expression

EXP

licochalcone B results in increased expression of FOXD1 mRNA

NCBI chr 5:73,446,266...73,448,777
Ensembl chr 5:73,444,827...73,448,777

G

forkhead box E3

increases expression

EXP

licochalcone B results in increased expression of FOXE3 mRNA

NCBI chr 1:47,416,285...47,418,052
Ensembl chr 1:47,416,285...47,418,052

G

forkhead box P4

increases expression

EXP

licochalcone B results in increased expression of FOXP4 mRNA

NCBI chr 6:41,546,381...41,602,384
Ensembl chr 6:41,546,363...41,602,384

G

Frey regulator of sperm-oocyte fusion 1

increases expression

EXP

licochalcone B results in increased expression of FREY1 mRNA

NCBI chr11:45,906,534...45,907,271
Ensembl chr11:45,906,513...45,907,272

G

FSHD region gene 2

increases expression

EXP

licochalcone B results in increased expression of FRG2 mRNA

NCBI chr 4:190,024,367...190,027,256
Ensembl chr 4:190,024,367...190,027,257

G

FSHD region gene 2 family member C

increases expression

EXP

licochalcone B results in increased expression of FRG2C mRNA

NCBI chr 3:75,664,328...75,667,173
Ensembl chr 3:75,664,328...75,667,220

G

FRY microtubule binding protein

decreases expression

EXP

licochalcone B results in decreased expression of FRY mRNA

NCBI chr13:32,031,774...32,299,125
Ensembl chr13:31,846,713...32,299,125

G

frizzled related protein

increases expression

EXP

licochalcone B results in increased expression of FRZB mRNA

NCBI chr 2:182,833,275...182,866,637
Ensembl chr 2:182,833,275...182,866,638

G

fucosyltransferase 1 (H blood group)

decreases expression

EXP

licochalcone B results in decreased expression of FUT1 mRNA

NCBI chr19:48,748,011...48,755,358
Ensembl chr19:48,748,011...48,755,390

G

FYVE and coiled-coil domain autophagy adaptor 1

decreases expression

EXP

licochalcone B results in decreased expression of FYCO1 mRNA

NCBI chr 3:45,917,903...45,995,824
Ensembl chr 3:45,917,903...45,995,838

G

frizzled class receptor 7

increases expression

EXP

licochalcone B results in increased expression of FZD7 mRNA

NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441

G

gamma-aminobutyric acid type A receptor subunit rho2

increases expression

EXP

licochalcone B results in increased expression of GABRR2 mRNA

NCBI chr 6:89,254,464...89,315,299
Ensembl chr 6:89,254,464...89,315,299

G

growth arrest and DNA damage inducible alpha

increases expression

EXP

licochalcone B results in increased expression of GADD45A mRNA

NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334

G

growth arrest and DNA damage inducible beta

increases expression

EXP

licochalcone B results in increased expression of GADD45B mRNA

NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805

G

polypeptide N-acetylgalactosaminyltransferase like 6

decreases expression

EXP

licochalcone B results in decreased expression of GALNTL6 mRNA

NCBI chr 4:171,813,404...173,041,559
Ensembl chr 4:171,812,254...173,041,559

G

galanin receptor 2

increases expression

EXP

licochalcone B results in increased expression of GALR2 mRNA

NCBI chr17:76,071,962...76,077,537
Ensembl chr17:76,074,781...76,077,537

G

GATA binding protein 2

increases expression

EXP

licochalcone B results in increased expression of GATA2 mRNA

NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,423...128,493,208

G

GATA binding protein 3

increases expression

EXP

licochalcone B results in increased expression of GATA3 mRNA

NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,315...8,075,198

G

gastrulation brain homeobox 2

increases expression

EXP

licochalcone B results in increased expression of GBX2 mRNA

NCBI chr 2:236,161,340...236,168,386
Ensembl chr 2:236,165,236...236,168,386

G

glial cells missing transcription factor 1

increases expression

EXP

licochalcone B results in increased expression of GCM1 mRNA

NCBI chr 6:53,126,961...53,148,841
Ensembl chr 6:53,126,961...53,148,841

G

GTP binding protein overexpressed in skeletal muscle

increases expression

EXP

licochalcone B results in increased expression of GEM mRNA

NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,249...94,262,461

G

guided entry of tail-anchored proteins factor 4

increases expression

EXP

licochalcone B results in increased expression of GET4 mRNA

NCBI chr 7:876,554...896,436
Ensembl chr 7:876,486...896,436

G

growth factor independent 1 transcriptional repressor

decreases expression

EXP

licochalcone B results in decreased expression of GFI1 mRNA

NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,472,360...92,486,925

G

glutamine-fructose-6-phosphate transaminase 2

increases expression

EXP

licochalcone B results in increased expression of GFPT2 mRNA

NCBI chr 5:180,300,698...180,353,336
Ensembl chr 5:180,300,682...180,353,339

G

GDNF family receptor alpha 3

increases expression

EXP

licochalcone B results in increased expression of GFRA3 mRNA

NCBI chr 5:138,252,380...138,274,621
Ensembl chr 5:138,252,380...138,274,621

G

GIPC PDZ domain containing family member 2

increases expression

EXP

licochalcone B results in increased expression of GIPC2 mRNA

NCBI chr 1:78,044,970...78,138,444
Ensembl chr 1:77,979,542...78,138,448

G

G protein subunit gamma 13

increases expression

EXP

licochalcone B results in increased expression of GNG13 mRNA

NCBI chr16:798,041...800,734
Ensembl chr16:798,041...800,734

G

granulysin

increases expression

EXP

licochalcone B results in increased expression of GNLY mRNA

NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852

G

glutathione S-transferase mu 5

increases expression

EXP

licochalcone B results in increased expression of GSTM5 mRNA

NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,746...109,775,428

G

granzyme M

increases expression

EXP

licochalcone B results in increased expression of GZMM mRNA

NCBI chr19:544,053...549,922
Ensembl chr19:544,034...549,924

G

H1.4 linker histone, cluster member

increases expression

EXP

licochalcone B results in increased expression of H1-4 mRNA

NCBI chr 6:26,156,329...26,157,115
Ensembl chr 6:26,156,329...26,157,115

G

H2A.B variant histone 3

increases expression

EXP

licochalcone B results in increased expression of H2AB3 mRNA

NCBI chr X:155,459,415...155,460,005
Ensembl chr X:155,459,415...155,460,005

G

H2A clustered histone 12

increases expression

EXP

licochalcone B results in increased expression of H2AC12 mRNA

NCBI chr 6:27,147,106...27,147,562
Ensembl chr 6:27,147,106...27,147,562

G

H2A clustered histone 14

increases expression

EXP

licochalcone B results in increased expression of H2AC14 mRNA

NCBI chr 6:27,814,302...27,814,777
Ensembl chr 6:27,814,302...27,814,777

G

H2A clustered histone 16

increases expression

EXP

licochalcone B results in increased expression of H2AC16 mRNA

NCBI chr 6:27,865,317...27,865,798
Ensembl chr 6:27,865,317...27,865,798

G

H2A clustered histone 19

increases expression

EXP

licochalcone B results in increased expression of H2AC19 mRNA

NCBI chr 1:149,851,061...149,851,594
Ensembl chr 1:149,851,061...149,851,652

G

H2A clustered histone 21

increases expression

EXP

licochalcone B results in increased expression of H2AC21 mRNA

NCBI chr 1:149,887,469...149,887,965
Ensembl chr 1:149,887,469...149,887,965

G

H2A clustered histone 8

increases expression

EXP

licochalcone B results in increased expression of H2AC8 mRNA

NCBI chr 6:26,216,921...26,217,437
Ensembl chr 6:26,216,921...26,218,515

G

H2A.X variant histone

increases expression
increases phosphorylation

EXP

licochalcone B results in increased expression of H2AX mRNA
licochalcone B results in increased phosphorylation of H2AX protein

PMID:33647349 PMID:35948134

NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465

G

H2B clustered histone 11

increases expression

EXP

licochalcone B results in increased expression of H2BC11 mRNA

NCBI chr 6:27,132,316...27,132,795
Ensembl chr 6:27,122,657...27,132,795

G

H2B clustered histone 12

increases expression

EXP

licochalcone B results in increased expression of H2BC12 mRNA

NCBI chr 6:27,138,293...27,146,858
Ensembl chr 6:27,137,298...27,146,857

G

H2B clustered histone 14

increases expression

EXP

licochalcone B results in increased expression of H2BC14 mRNA

NCBI chr 6:27,815,022...27,815,489
Ensembl chr 6:27,815,022...27,815,489

G

H2B clustered histone 17

increases expression

EXP

licochalcone B results in increased expression of H2BC17 mRNA

NCBI chr 6:27,893,425...27,893,891
Ensembl chr 6:27,893,425...27,893,891

G

H2B clustered histone 18

increases expression

EXP

licochalcone B results in increased expression of H2BC18 mRNA

NCBI chr 1:149,782,689...149,812,370
Ensembl chr 1:149,782,689...149,812,373

G

H2B clustered histone 4

increases expression

EXP

licochalcone B results in increased expression of H2BC4 mRNA

NCBI chr 6:26,113,170...26,123,926
Ensembl chr 6:26,086,317...26,124,016

G

H2B clustered histone 5

increases expression

EXP

licochalcone B results in increased expression of H2BC5 mRNA

NCBI chr 6:26,158,121...26,171,349
Ensembl chr 6:26,158,122...26,171,349

G

H2B clustered histone 6

increases expression

EXP

licochalcone B results in increased expression of H2BC6 mRNA

NCBI chr 6:26,183,761...26,184,230
Ensembl chr 6:26,172,059...26,184,655

G

H2B clustered histone 7

increases expression

EXP

licochalcone B results in increased expression of H2BC7 mRNA

NCBI chr 6:26,199,516...26,199,988
Ensembl chr 6:26,199,516...26,199,988

G

H2B clustered histone 8

increases expression

EXP

licochalcone B results in increased expression of H2BC8 mRNA

NCBI chr 6:26,216,200...26,216,688
Ensembl chr 6:26,216,200...26,216,688

G

H2B clustered histone 9

increases expression

EXP

licochalcone B results in increased expression of H2BC9 mRNA

NCBI chr 6:26,251,614...26,252,075
Ensembl chr 6:26,251,614...26,252,075

G

H3 clustered histone 1

increases expression

EXP

licochalcone B results in increased expression of H3C1 mRNA

NCBI chr 6:26,020,451...26,020,958
Ensembl chr 6:26,020,451...26,021,487

G

H3 clustered histone 10

increases expression

EXP

licochalcone B results in increased expression of H3C10 mRNA

NCBI chr 6:27,810,051...27,810,536
Ensembl chr 6:27,810,051...27,811,300

G

H3 clustered histone 13

increases expression

EXP

licochalcone B results in increased expression of H3C13 mRNA

NCBI chr 1:149,813,225...149,813,693
Ensembl chr 1:149,813,225...149,813,693

G

H3 clustered histone 7

increases expression

EXP

licochalcone B results in increased expression of H3C7 mRNA

NCBI chr 6:26,250,142...26,250,635
Ensembl chr 6:26,250,142...26,250,635

G

H3 clustered histone 8

increases expression

EXP

licochalcone B results in increased expression of H3C8 mRNA

NCBI chr 6:26,270,918...26,271,413
Ensembl chr 6:26,270,918...26,271,413

G

H4 clustered histone 1

increases expression

EXP

licochalcone B results in increased expression of H4C1 mRNA

NCBI chr 6:26,021,649...26,022,050
Ensembl chr 6:26,021,649...26,022,847

G

H4 clustered histone 14

increases expression

EXP

licochalcone B results in increased expression of H4C14 mRNA

NCBI chr 1:149,832,657...149,833,052
Ensembl chr 1:149,832,657...149,839,767

G

H4 clustered histone 3

increases expression

EXP

licochalcone B results in increased expression of H4C3 mRNA

NCBI chr 6:26,103,933...26,104,337
Ensembl chr 6:26,103,933...26,104,337

G

H4 clustered histone 4

increases expression

EXP

licochalcone B results in increased expression of H4C4 mRNA

NCBI chr 6:26,188,710...26,189,112
Ensembl chr 6:26,188,710...26,189,112

G

H4 clustered histone 5

increases expression

EXP

licochalcone B results in increased expression of H4C5 mRNA

NCBI chr 6:26,204,610...26,205,021
Ensembl chr 6:26,204,610...26,205,021

G

H4 clustered histone 9

increases expression

EXP

licochalcone B results in increased expression of H4C9 mRNA

NCBI chr 6:27,139,282...27,139,678
Ensembl chr 6:27,139,282...27,140,640

G

hepcidin antimicrobial peptide

increases expression

EXP

licochalcone B results in increased expression of HAMP mRNA

NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143

G

hyaluronan and proteoglycan link protein 2

increases expression

EXP

licochalcone B results in increased expression of HAPLN2 mRNA

NCBI chr 1:156,601,504...156,625,725
Ensembl chr 1:156,619,331...156,626,361

G

hyaluronan and proteoglycan link protein 3

increases expression

EXP

licochalcone B results in increased expression of HAPLN3 mRNA

NCBI chr15:88,877,294...88,895,544
Ensembl chr15:88,877,294...88,895,597

G

hyaluronan synthase 1

increases expression

EXP

licochalcone B results in increased expression of HAS1 mRNA

NCBI chr19:51,713,112...51,723,991
Ensembl chr19:51,713,112...51,723,991

G

hyaluronan synthase 3

increases expression

EXP

licochalcone B results in increased expression of HAS3 mRNA

NCBI chr16:69,083,484...69,118,719
Ensembl chr16:69,105,653...69,118,719

G

hemoglobin subunit alpha 1

increases expression

EXP

licochalcone B results in increased expression of HBA1 mRNA

NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522

G

heparin binding EGF like growth factor

increases expression

EXP

licochalcone B results in increased expression of HBEGF mRNA

NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,614

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

EXP

licochalcone B results in increased expression of HERPUD1 mRNA

NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,930,815...56,944,864

G

hes family bHLH transcription factor 6

increases expression

EXP

licochalcone B results in increased expression of HES6 mRNA

NCBI chr 2:238,238,267...238,240,038
Ensembl chr 2:238,238,267...238,240,662

G

hes family bHLH transcription factor 7

increases expression

EXP

licochalcone B results in increased expression of HES7 mRNA

NCBI chr17:8,120,592...8,126,634
Ensembl chr17:8,120,592...8,124,106

G

HIC ZBTB transcriptional repressor 2

increases expression

EXP

licochalcone B results in increased expression of HIC2 mRNA

NCBI chr22:21,417,371...21,451,463
Ensembl chr22:21,416,504...21,451,463

G

homeodomain interacting protein kinase 4

increases expression

EXP

licochalcone B results in increased expression of HIPK4 mRNA

NCBI chr19:40,379,271...40,390,181
Ensembl chr19:40,379,271...40,390,181

G

heme oxygenase 1

increases expression

EXP

licochalcone B results in increased expression of HMOX1 mRNA

NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214

G

homer scaffold protein 2

increases expression

EXP

licochalcone B results in increased expression of HOMER2 mRNA

NCBI chr15:82,834,661...82,986,157
Ensembl chr15:82,834,664...82,986,153

G

homeobox C4

decreases expression

EXP

licochalcone B results in decreased expression of HOXC4 mRNA

NCBI chr12:54,016,888...54,056,030
Ensembl chr12:54,016,931...54,056,030

G

hemopexin

increases expression

EXP

licochalcone B results in increased expression of HPX mRNA

NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,006...6,442,617

G

heat shock protein family A (Hsp70) member 1A

increases expression

EXP

licochalcone B results in increased expression of HSPA1A mRNA

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,994

G

heat shock protein family A (Hsp70) member 1B

increases expression

EXP

licochalcone B results in increased expression of HSPA1B mRNA

NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254

G

heat shock protein family A (Hsp70) member 1 like

increases expression

EXP

licochalcone B results in increased expression of HSPA1L mRNA

NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,788

G

heat shock protein family A (Hsp70) member 6

increases expression

EXP

licochalcone B results in increased expression of HSPA6 mRNA

NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894

G

heat shock protein family A (Hsp70) member 8

increases expression

EXP

licochalcone B results in increased expression of HSPA8 mRNA

NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,485...123,063,230

G

heat shock protein family B (small) member 8

increases expression

EXP

licochalcone B results in increased expression of HSPB8 mRNA

NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855

G

heat shock protein family B (small) member 9

increases expression

EXP

licochalcone B results in increased expression of HSPB9 mRNA

NCBI chr17:42,122,804...42,123,352
Ensembl chr17:42,122,804...42,123,352

G

heat shock protein family H (Hsp110) member 1

increases expression

EXP

licochalcone B results in increased expression of HSPH1 mRNA

NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,876...31,162,388

G

HUS1 checkpoint clamp component B

increases expression

EXP

licochalcone B results in increased expression of HUS1B mRNA

NCBI chr 6:655,939...657,100
Ensembl chr 6:655,939...657,100

G

inhibitor of DNA binding 2

increases expression

EXP

licochalcone B results in increased expression of ID2 mRNA

NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461

G

immediate early response 5

increases expression

EXP

licochalcone B results in increased expression of IER5 mRNA

NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900

G

immediate early response 5 like

increases expression

EXP

licochalcone B results in increased expression of IER5L mRNA

NCBI chr 9:129,175,552...129,178,261
Ensembl chr 9:129,175,552...129,178,261

G

IFI30 lysosomal thiol reductase

increases expression

EXP

licochalcone B results in increased expression of IFI30 mRNA

NCBI chr19:18,173,813...18,178,117
Ensembl chr19:18,173,162...18,178,121

G

interferon induced with helicase C domain 1

decreases expression

EXP

licochalcone B results in decreased expression of IFIH1 mRNA

NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684

G

IGF like family member 4

decreases expression

EXP

licochalcone B results in decreased expression of IGFL4 mRNA

NCBI chr19:46,039,182...46,077,629
Ensembl chr19:46,039,182...46,077,118

G

immunoglobulin superfamily member 11

increases expression

EXP

licochalcone B results in increased expression of IGSF11 mRNA

NCBI chr 3:118,900,557...119,146,020
Ensembl chr 3:118,900,557...119,146,068

G

interleukin 17 receptor E like

decreases expression

EXP

licochalcone B results in decreased expression of IL17REL mRNA

NCBI chr22:49,991,811...50,012,765
Ensembl chr22:49,991,811...50,012,765

G

interleukin 1 alpha

decreases expression

EXP

licochalcone B results in decreased expression of IL1A mRNA

NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493

G

interleukin 1 beta

decreases expression
multiple interactions

EXP
ISO

licochalcone B results in decreased expression of IL1B mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]

PMID:25451593 PMID:33647349

NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816

G

interleukin 1 receptor type 1

decreases expression

EXP

licochalcone B results in decreased expression of IL1R1 mRNA

NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,063,933...102,179,874

G

interleukin 2 receptor subunit beta

decreases expression

EXP

licochalcone B results in decreased expression of IL2RB mRNA

NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,176,676

G

interleukin 6

decreases expression
multiple interactions

EXP
ISO

licochalcone B results in decreased expression of IL6 mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]

PMID:25451593 PMID:33647349

NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002

G

InaF motif containing 1

increases expression

EXP

licochalcone B results in increased expression of INAFM1 mRNA

NCBI chr19:47,274,423...47,275,723
Ensembl chr19:47,274,373...47,277,755

G

inhibin subunit beta E

decreases expression

EXP

licochalcone B results in decreased expression of INHBE mRNA

NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280

G

inka box actin regulator 1

increases expression

EXP

licochalcone B results in increased expression of INKA1 mRNA

NCBI chr 3:49,803,261...49,805,030
Ensembl chr 3:49,803,240...49,805,030

G

INSM transcriptional repressor 2

increases expression

EXP

licochalcone B results in increased expression of INSM2 mRNA

NCBI chr14:35,534,164...35,537,054
Ensembl chr14:35,534,164...35,537,054

G

interferon regulatory factor 7

increases expression

EXP

licochalcone B results in increased expression of IRF7 mRNA

NCBI chr11:612,555...615,950
Ensembl chr11:612,551...615,983

G

immunity related GTPase cinema

increases expression

EXP

licochalcone B results in increased expression of IRGC mRNA

NCBI chr19:43,716,076...43,720,021
Ensembl chr19:43,716,076...43,720,021

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

increases expression

EXP

licochalcone B results in increased expression of JMJD6 mRNA

NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,784

G

junctophilin 4

increases expression

EXP

licochalcone B results in increased expression of JPH4 mRNA

NCBI chr14:23,568,038...23,578,790
Ensembl chr14:23,568,038...23,578,790

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

EXP
ISO

licochalcone B results in increased expression of JUN mRNA
licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of JUN protein]

PMID:25451593 PMID:33647349

NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

licochalcone B results in increased expression of JUNB mRNA

NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

licochalcone B results in increased expression of JUND mRNA

NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622

G

KN motif and ankyrin repeat domains 3

increases expression

EXP

licochalcone B results in increased expression of KANK3 mRNA

NCBI chr19:8,322,584...8,343,262
Ensembl chr19:8,322,582...8,343,268

G

kelch repeat and BTB domain containing 8

increases expression

EXP

licochalcone B results in increased expression of KBTBD8 mRNA

NCBI chr 3:66,998,307...67,011,210
Ensembl chr 3:66,998,307...67,011,210

G

potassium voltage-gated channel subfamily B member 1

increases expression

EXP

licochalcone B results in increased expression of KCNB1 mRNA

NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297

G

potassium voltage-gated channel modifier subfamily G member 2

increases expression

EXP

licochalcone B results in increased expression of KCNG2 mRNA

NCBI chr18:79,797,938...79,900,100
Ensembl chr18:79,797,904...79,900,184

G

potassium voltage-gated channel subfamily H member 5

decreases expression

EXP

licochalcone B results in decreased expression of KCNH5 mRNA

NCBI chr14:62,699,464...63,045,458
Ensembl chr14:62,699,464...63,102,037

G

potassium two pore domain channel subfamily K member 3

decreases expression

EXP

licochalcone B results in decreased expression of KCNK3 mRNA

NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420

G

potassium two pore domain channel subfamily K member 4

increases expression

EXP

licochalcone B results in increased expression of KCNK4 mRNA

NCBI chr11:64,291,302...64,300,031
Ensembl chr11:64,291,302...64,300,031

G

potassium channel tetramerization domain containing 5

increases expression

EXP

licochalcone B results in increased expression of KCTD5 mRNA

NCBI chr16:2,682,523...2,709,030
Ensembl chr16:2,682,521...2,709,030

G

keratinocyte differentiation factor 1

increases expression

EXP

licochalcone B results in increased expression of KDF1 mRNA

NCBI chr 1:26,949,562...26,960,468
Ensembl chr 1:26,949,556...26,960,788

G

KIAA0825

decreases expression

EXP

licochalcone B results in decreased expression of KIAA0825 mRNA

NCBI chr 5:94,150,851...94,618,604
Ensembl chr 5:94,150,851...94,618,604

G

kinesin family member 5A

increases expression

EXP

licochalcone B results in increased expression of KIF5A mRNA

NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633

G

kirre like nephrin family adhesion molecule 2

increases expression

EXP

licochalcone B results in increased expression of KIRREL2 mRNA

NCBI chr19:35,851,399...35,867,136
Ensembl chr19:35,851,369...35,867,145

G

KLF transcription factor 2

increases expression

EXP

licochalcone B results in increased expression of KLF2 mRNA

NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685

G

KLF transcription factor 4

increases expression

EXP

licochalcone B results in increased expression of KLF4 mRNA

NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482

G

kelch like family member 13

decreases expression

EXP

licochalcone B results in decreased expression of KLHL13 mRNA

NCBI chr X:117,897,813...118,117,340
Ensembl chr X:117,897,794...118,117,340

G

kelch like family member 21

increases expression

EXP

licochalcone B results in increased expression of KLHL21 mRNA

NCBI chr 1:6,590,724...6,602,869
Ensembl chr 1:6,590,724...6,614,607

G

kelch like family member 25

increases expression

EXP

licochalcone B results in increased expression of KLHL25 mRNA

NCBI chr15:85,759,326...85,794,925
Ensembl chr15:85,759,326...85,794,948

G

kinase non-catalytic C-lobe domain containing 1

decreases expression

EXP

licochalcone B results in decreased expression of KNDC1 mRNA

NCBI chr10:133,160,219...133,226,412
Ensembl chr10:133,160,034...133,226,412

G

KRAB-A domain containing 2

decreases expression

EXP

licochalcone B results in decreased expression of KRABD2 mRNA

NCBI chr17:8,358,822...8,376,704
Ensembl chr17:8,356,902...8,376,738

G

keratin 16

increases expression

EXP

licochalcone B results in increased expression of KRT16 mRNA

NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899

G

lymphocyte activating 3

increases expression

EXP

licochalcone B results in increased expression of LAG3 mRNA

NCBI chr12:6,772,520...6,778,455
Ensembl chr12:6,772,360...6,778,455

G

low density lipoprotein receptor class A domain containing 2

increases expression

EXP

licochalcone B results in increased expression of LDLRAD2 mRNA

NCBI chr 1:21,812,265...21,825,225
Ensembl chr 1:21,812,265...21,825,225

G

low density lipoprotein receptor class A domain containing 4

increases expression

EXP

licochalcone B results in increased expression of LDLRAD4 mRNA

NCBI chr18:13,217,682...13,652,754
Ensembl chr18:13,216,173...13,652,755

G

leukocyte receptor cluster member 1

increases expression

EXP

licochalcone B results in increased expression of LENG1 mRNA

NCBI chr19:54,155,161...54,159,721
Ensembl chr19:54,155,161...54,159,721

G

galectin 4

increases expression

EXP

licochalcone B results in increased expression of LGALS4 mRNA

NCBI chr19:38,801,674...38,812,945
Ensembl chr19:38,801,671...38,813,070

G

leucine rich repeat LGI family member 4

increases expression

EXP

licochalcone B results in increased expression of LGI4 mRNA

NCBI chr19:35,124,513...35,135,059
Ensembl chr19:35,124,510...35,142,451

G

lengsin, lens protein with glutamine synthetase domain

decreases expression

EXP

licochalcone B results in decreased expression of LGSN mRNA

NCBI chr 6:63,275,951...63,573,607
Ensembl chr 6:63,275,951...63,319,983

G

luteinizing hormone subunit beta

increases expression

EXP

licochalcone B results in increased expression of LHB mRNA

NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091

G

long intergenic non-protein coding RNA 3040

decreases expression

EXP

licochalcone B results in decreased expression of LINC03040 mRNA

NCBI chr 6:44,000,585...44,007,612
Ensembl chr 6:44,000,580...44,007,612

G

ligand of numb-protein X 1

decreases expression

EXP

licochalcone B results in decreased expression of LNX1 mRNA

NCBI chr 4:53,459,301...53,652,477
Ensembl chr 4:53,459,301...53,701,405

G

leucine rich repeat and fibronectin type III domain containing 1

decreases expression

EXP

licochalcone B results in decreased expression of LRFN1 mRNA

NCBI chr19:39,306,566...39,320,863
Ensembl chr19:39,306,566...39,320,966

G

leucine rich repeats and guanylate kinase domain containing

decreases expression

EXP

licochalcone B results in decreased expression of LRGUK mRNA

NCBI chr 7:134,127,340...134,276,685
Ensembl chr 7:134,127,299...134,264,595

G

leucine rich repeat containing 15

increases expression

EXP

licochalcone B results in increased expression of LRRC15 mRNA

NCBI chr 3:194,355,249...194,369,743
Ensembl chr 3:194,355,249...194,369,743

G

leucine rich repeat containing 43

increases expression

EXP

licochalcone B results in increased expression of LRRC43 mRNA

NCBI chr12:122,167,719...122,203,471
Ensembl chr12:122,167,738...122,203,471

G

leucine rich repeat containing 8 VRAC subunit A

increases expression

EXP

licochalcone B results in increased expression of LRRC8A mRNA

NCBI chr 9:128,882,133...128,918,039
Ensembl chr 9:128,882,133...128,918,042

G

leucine rich repeats and IQ motif containing 3

decreases expression

EXP

licochalcone B results in decreased expression of LRRIQ3 mRNA

NCBI chr 1:74,026,015...74,198,176
Ensembl chr 1:74,026,015...74,198,187

G

leucine rich repeat neuronal 4

increases expression

EXP

licochalcone B results in increased expression of LRRN4 mRNA

NCBI chr20:6,040,546...6,054,060
Ensembl chr20:6,037,376...6,060,313

G

leucine rich single-pass membrane protein 1

increases expression

EXP

licochalcone B results in increased expression of LSMEM1 mRNA

NCBI chr 7:112,480,304...112,491,062
Ensembl chr 7:112,480,853...112,491,062

G

latent transforming growth factor beta binding protein 1

decreases expression

EXP

licochalcone B results in decreased expression of LTBP1 mRNA

NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,472...33,399,509

G

lymphocyte antigen 6 family member G6C

increases expression

EXP

licochalcone B results in increased expression of LY6G6C mRNA

NCBI chr 6:31,718,648...31,721,746
Ensembl chr 6:31,718,648...31,721,746

G

MAF bZIP transcription factor A

increases expression

EXP

licochalcone B results in increased expression of MAFA mRNA

NCBI chr 8:143,428,064...143,430,732
Ensembl chr 8:143,419,182...143,430,732

G

MAF bZIP transcription factor B

increases expression

EXP

licochalcone B results in increased expression of MAFB mRNA

NCBI chr20:40,685,848...40,689,236
Ensembl chr20:40,685,848...40,689,236

G

MAF bZIP transcription factor F

increases expression

EXP

licochalcone B results in increased expression of MAFF mRNA

NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,511

G

MAGE family member B3

increases expression

EXP

licochalcone B results in increased expression of MAGEB3 mRNA

NCBI chr X:30,230,657...30,237,495
Ensembl chr X:30,230,657...30,237,495

G

mastermind like transcriptional coactivator 2

decreases expression

EXP

licochalcone B results in decreased expression of MAML2 mRNA

NCBI chr11:95,976,598...96,343,195
Ensembl chr11:95,976,598...96,343,195

G

mannosidase alpha class 1C member 1

increases expression

EXP

licochalcone B results in increased expression of MAN1C1 mRNA

NCBI chr 1:25,616,791...25,784,450
Ensembl chr 1:25,616,791...25,786,205

G

MANSC domain containing 1

decreases expression

EXP

licochalcone B results in decreased expression of MANSC1 mRNA

NCBI chr12:12,326,056...12,350,242
Ensembl chr12:12,326,056...12,350,483

G

microtubule associated protein 1A

increases expression

EXP

licochalcone B results in increased expression of MAP1A mRNA

NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620

G

microtubule associated protein 1 light chain 3 beta 2

increases expression

EXP

licochalcone B results in increased expression of MAP1LC3B2 mRNA

NCBI chr12:116,559,381...116,576,606
Ensembl chr12:116,548,105...116,576,606

G

mitogen-activated protein kinase kinase 3

increases expression

EXP

licochalcone B results in increased expression of MAP2K3 mRNA

NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,240

G

mitogen-activated protein kinase kinase kinase 14

increases expression

EXP

licochalcone B results in increased expression of MAP3K14 mRNA

NCBI chr17:45,263,119...45,317,020
Ensembl chr17:45,263,119...45,317,112

G

MAP7 domain containing 2

increases expression

EXP

licochalcone B results in increased expression of MAP7D2 mRNA

NCBI chr X:20,006,713...20,116,907
Ensembl chr X:20,006,713...20,117,065

G

mitogen-activated protein kinase 1

multiple interactions
increases phosphorylation

ISO
EXP

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
licochalcone B results in increased phosphorylation of MAPK1 protein

PMID:25451593 PMID:35948134

NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,755,537...21,867,680

G

mitogen-activated protein kinase 3

multiple interactions
increases phosphorylation

ISO
EXP

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
licochalcone B results in increased phosphorylation of MAPK3 protein

PMID:25451593 PMID:35948134

NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506

G

mitogen-activated protein kinase 8

multiple interactions
increases phosphorylation

ISO
EXP

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
licochalcone B results in increased phosphorylation of MAPK8 protein

PMID:25451593 PMID:35948134

NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360

G

mitogen-activated protein kinase 8 interacting protein 1

increases expression

EXP

licochalcone B results in increased expression of MAPK8IP1 mRNA

NCBI chr11:45,885,651...45,906,465
Ensembl chr11:45,885,618...45,906,470

G

mitogen-activated protein kinase 9

multiple interactions
increases phosphorylation

ISO
EXP

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]
licochalcone B results in increased phosphorylation of MAPK9 protein

PMID:25451593 PMID:35948134

NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099

G

membrane associated ring-CH-type finger 1

decreases expression

EXP

licochalcone B results in decreased expression of MARCHF1 mRNA

NCBI chr 4:163,524,298...164,384,019
Ensembl chr 4:163,524,298...164,384,050

G

MARCKS like 1

increases expression

EXP

licochalcone B results in increased expression of MARCKSL1 mRNA

NCBI chr 1:32,333,839...32,336,233
Ensembl chr 1:32,333,827...32,336,233

G

MARCO like

decreases expression

EXP

licochalcone B results in decreased expression of MARCOL mRNA

NCBI chr 5:148,238,525...148,243,580
Ensembl chr 5:148,221,650...148,243,580

G

MBL associated serine protease 1

decreases expression

EXP

licochalcone B results in decreased expression of MASP1 mRNA

NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980

G

melanocortin 5 receptor

increases expression

EXP

licochalcone B results in increased expression of MC5R mRNA

NCBI chr18:13,824,149...13,827,323
Ensembl chr18:13,824,149...13,827,323

G

mucolipin TRP cation channel 1

increases expression

EXP

licochalcone B results in increased expression of MCOLN1 mRNA

NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,611...7,534,009

G

MyoD family inhibitor

increases expression

EXP

licochalcone B results in increased expression of MDFI mRNA

NCBI chr 6:41,637,018...41,654,244
Ensembl chr 6:41,636,840...41,654,246

G

MAM domain containing glycosylphosphatidylinositol anchor 1

increases expression

EXP

licochalcone B results in increased expression of MDGA1 mRNA

NCBI chr 6:37,630,679...37,697,883
Ensembl chr 6:37,630,679...37,699,306

G

Meis homeobox 1

decreases expression

EXP

licochalcone B results in decreased expression of MEIS1 mRNA

NCBI chr 2:66,435,125...66,573,869
Ensembl chr 2:66,433,452...66,573,898

G

mesenchyme homeobox 1

decreases expression

EXP

licochalcone B results in decreased expression of MEOX1 mRNA

NCBI chr17:43,640,389...43,661,922
Ensembl chr17:43,640,389...43,661,922

G

meteorin like, glial cell differentiation regulator

increases expression

EXP

licochalcone B results in increased expression of METRNL mRNA

NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122

G

mex-3 RNA binding family member A

decreases expression

EXP

licochalcone B results in decreased expression of MEX3A mRNA

NCBI chr 1:156,072,013...156,082,465
Ensembl chr 1:156,072,013...156,082,465

G

mex-3 RNA binding family member B

increases expression

EXP

licochalcone B results in increased expression of MEX3B mRNA

NCBI chr15:82,041,778...82,046,018
Ensembl chr15:82,041,778...82,046,119

G

mex-3 RNA binding family member D

increases expression

EXP

licochalcone B results in increased expression of MEX3D mRNA

NCBI chr19:1,554,672...1,568,325
Ensembl chr19:1,554,672...1,568,325

G

milk fat globule EGF and factor V/VIII domain containing

increases expression

EXP

licochalcone B results in increased expression of MFGE8 mRNA

NCBI chr15:88,898,683...88,913,379
Ensembl chr15:88,898,683...88,913,468

G

mitochondria localized glutamic acid rich protein

increases expression

EXP

licochalcone B results in increased expression of MGARP mRNA

NCBI chr 4:139,266,165...139,280,225
Ensembl chr 4:139,266,165...139,280,346

G

MICAL like 2

increases expression

EXP

licochalcone B results in increased expression of MICALL2 mRNA

NCBI chr 7:1,434,359...1,459,470
Ensembl chr 7:1,428,465...1,459,496

G

microRNA 1246

increases expression

EXP

licochalcone B results in increased expression of MIR1246 mRNA

NCBI chr 2:176,600,980...176,601,052
Ensembl chr 2:176,600,980...176,601,052

G

microRNA 1248

increases expression

EXP

licochalcone B results in increased expression of MIR1248 mRNA

NCBI chr 3:186,786,672...186,786,777
Ensembl chr 3:186,786,672...186,786,777

G

microRNA 125b-1

decreases expression

EXP

licochalcone B results in decreased expression of MIR125B1 mRNA

NCBI chr11:122,099,757...122,099,844
Ensembl chr11:122,099,757...122,099,844

G

microRNA 126

decreases expression

EXP

licochalcone B results in decreased expression of MIR126 mRNA

NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686

G

microRNA 1260a

decreases expression

EXP

licochalcone B results in decreased expression of MIR1260A mRNA

NCBI chr14:77,266,218...77,266,290
Ensembl chr14:77,266,218...77,266,290

G

microRNA 1260b

decreases expression

EXP

licochalcone B results in decreased expression of MIR1260B mRNA

NCBI chr11:96,341,438...96,341,526
Ensembl chr11:96,341,438...96,341,526

G

microRNA 1268a

decreases expression

EXP

licochalcone B results in decreased expression of MIR1268A mRNA

NCBI chr15:22,225,278...22,225,329
Ensembl chr15:22,225,278...22,225,329

G

microRNA 1268b

decreases expression

EXP

licochalcone B results in decreased expression of MIR1268B mRNA

NCBI chr17:80,098,828...80,098,877
Ensembl chr17:80,098,828...80,098,877

G

microRNA 127

increases expression

EXP

licochalcone B results in increased expression of MIR127 mRNA

NCBI chr14:100,882,979...100,883,075
Ensembl chr14:100,882,979...100,883,075

G

microRNA 1277

increases expression

EXP

licochalcone B results in increased expression of MIR1277 mRNA

NCBI chr X:118,386,394...118,386,471
Ensembl chr X:118,386,394...118,386,471

G

microRNA 1290

increases expression

EXP

licochalcone B results in increased expression of MIR1290 mRNA

NCBI chr 1:18,897,071...18,897,148
Ensembl chr 1:18,897,071...18,897,148

G

microRNA 1291

increases expression

EXP

licochalcone B results in increased expression of MIR1291 mRNA

NCBI chr12:48,654,444...48,654,530
Ensembl chr12:48,654,444...48,654,530

G

microRNA 1303

decreases expression

EXP

licochalcone B results in decreased expression of MIR1303 mRNA

NCBI chr 5:154,685,776...154,685,861
Ensembl chr 5:154,685,776...154,685,861

G

microRNA 143

increases expression

EXP

licochalcone B results in increased expression of MIR143 mRNA

NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023

G

microRNA 146a

increases expression

EXP

licochalcone B results in increased expression of MIR146A mRNA

NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450

G

microRNA 148a

decreases expression

EXP

licochalcone B results in decreased expression of MIR148A mRNA

NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986

G

microRNA 16-1

decreases expression

EXP

licochalcone B results in decreased expression of MIR16-1 mRNA

NCBI chr13:50,048,973...50,049,061
Ensembl chr13:50,048,973...50,049,061

G

microRNA 181a-1

decreases expression

EXP

licochalcone B results in decreased expression of MIR181A1 mRNA

NCBI chr 1:198,859,044...198,859,153
Ensembl chr 1:198,859,044...198,859,153

G

microRNA 181b-1

decreases expression

EXP

licochalcone B results in decreased expression of MIR181B1 mRNA

NCBI chr 1:198,858,873...198,858,982
Ensembl chr 1:198,858,873...198,858,982

G

microRNA 191

decreases expression

EXP

licochalcone B results in decreased expression of MIR191 mRNA

NCBI chr 3:49,020,618...49,020,709
Ensembl chr 3:49,020,618...49,020,709

G

microRNA 193a

increases expression

EXP

licochalcone B results in increased expression of MIR193A mRNA

NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083

G

microRNA 19a

increases expression

EXP

licochalcone B results in increased expression of MIR19A mRNA

NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972

G

microRNA 200a

increases expression

EXP

licochalcone B results in increased expression of MIR200A mRNA

NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952

G

microRNA 206

increases expression

EXP

licochalcone B results in increased expression of MIR206 mRNA

NCBI chr 6:52,144,349...52,144,434
Ensembl chr 6:52,144,349...52,144,434

G

microRNA 210

decreases expression

EXP

licochalcone B results in decreased expression of MIR210 mRNA

NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198

G

microRNA 219a-2

increases expression

EXP

licochalcone B results in increased expression of MIR219A2 mRNA

NCBI chr 9:128,392,618...128,392,714
Ensembl chr 9:128,392,618...128,392,714

G

microRNA 222

decreases expression

EXP

licochalcone B results in decreased expression of MIR222 mRNA

NCBI chr X:45,747,015...45,747,124
Ensembl chr X:45,747,015...45,747,124

G

microRNA 23b

decreases expression

EXP

licochalcone B results in decreased expression of MIR23B mRNA

NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304

G

microRNA 25

decreases expression

EXP

licochalcone B results in decreased expression of MIR25 mRNA

NCBI chr 7:100,093,560...100,093,643
Ensembl chr 7:100,093,560...100,093,643

G

microRNA 26a-2

decreases expression

EXP

licochalcone B results in decreased expression of MIR26A2 mRNA

NCBI chr12:57,824,609...57,824,692
Ensembl chr12:57,824,609...57,824,692

G

microRNA 27a

decreases expression

EXP

licochalcone B results in decreased expression of MIR27A mRNA

NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517

G

microRNA 27b

decreases expression

EXP

licochalcone B results in decreased expression of MIR27B mRNA

NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541

G

microRNA 296

decreases expression

EXP

licochalcone B results in decreased expression of MIR296 mRNA

NCBI chr20:58,817,615...58,817,694
Ensembl chr20:58,817,615...58,817,694

G

microRNA 301a

decreases expression

EXP

licochalcone B results in decreased expression of MIR301A mRNA

NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221

G

microRNA 301b

increases expression

EXP

licochalcone B results in increased expression of MIR301B mRNA

NCBI chr22:21,652,981...21,653,058
Ensembl chr22:21,652,981...21,653,058

G

microRNA 30b

decreases expression

EXP

licochalcone B results in decreased expression of MIR30B mRNA

NCBI chr 8:134,800,520...134,800,607
Ensembl chr 8:134,800,520...134,800,607

G

microRNA 30c-1

decreases expression

EXP

licochalcone B results in decreased expression of MIR30C1 mRNA

NCBI chr 1:40,757,284...40,757,372
Ensembl chr 1:40,757,284...40,757,372

G

microRNA 30d

decreases expression

EXP

licochalcone B results in decreased expression of MIR30D mRNA

NCBI chr 8:134,804,876...134,804,945
Ensembl chr 8:134,804,876...134,804,945

G

microRNA 335

decreases expression

EXP

licochalcone B results in decreased expression of MIR335 mRNA

NCBI chr 7:130,496,111...130,496,204
Ensembl chr 7:130,496,111...130,496,204

G

microRNA 33a

decreases expression

EXP

licochalcone B results in decreased expression of MIR33A mRNA

NCBI chr22:41,900,944...41,901,012
Ensembl chr22:41,900,944...41,901,012

G

microRNA 33b

decreases expression

EXP

licochalcone B results in decreased expression of MIR33B mRNA

NCBI chr17:17,813,836...17,813,931
Ensembl chr17:17,813,836...17,813,931

G

microRNA 3609

increases expression

EXP

licochalcone B results in increased expression of MIR3609 mRNA

NCBI chr 7:98,881,650...98,881,729
Ensembl chr 7:98,881,650...98,881,729

G

microRNA 3651

increases expression

EXP

licochalcone B results in increased expression of MIR3651 mRNA

NCBI chr 9:92,292,458...92,292,547
Ensembl chr 9:92,292,458...92,292,547

G

microRNA 365a

decreases expression

EXP

licochalcone B results in decreased expression of MIR365A mRNA

NCBI chr16:14,309,285...14,309,371
Ensembl chr16:14,309,285...14,309,371

G

microRNA 374b

decreases expression

EXP

licochalcone B results in decreased expression of MIR374B mRNA

NCBI chr X:74,218,547...74,218,618
Ensembl chr X:74,218,547...74,218,618

G

microRNA 378g

increases expression

EXP

licochalcone B results in increased expression of MIR378G mRNA

NCBI chr 1:94,745,860...94,745,900
Ensembl chr 1:94,745,860...94,745,900

G

microRNA 3960

increases expression

EXP

licochalcone B results in increased expression of MIR3960 mRNA

NCBI chr 9:127,785,833...127,785,923
Ensembl chr 9:127,785,833...127,785,923

G

microRNA 424

decreases expression

EXP

licochalcone B results in decreased expression of MIR424 mRNA

NCBI chr X:134,546,614...134,546,711
Ensembl chr X:134,546,614...134,546,711

G

microRNA 4286

decreases expression

EXP

licochalcone B results in decreased expression of MIR4286 mRNA

NCBI chr 8:10,666,978...10,667,070
Ensembl chr 8:10,666,978...10,667,070

G

microRNA 4449

increases expression

EXP

licochalcone B results in increased expression of MIR4449 mRNA

NCBI chr 4:52,712,682...52,712,747
Ensembl chr 4:52,712,682...52,712,747

G

microRNA 4454

decreases expression

EXP

licochalcone B results in decreased expression of MIR4454 mRNA

NCBI chr 4:163,093,574...163,093,628
Ensembl chr 4:163,093,574...163,093,628

G

microRNA 4488

increases expression

EXP

licochalcone B results in increased expression of MIR4488 mRNA

NCBI chr11:61,508,596...61,508,657
Ensembl chr11:61,508,596...61,508,657

G

microRNA 4508

increases expression

EXP

licochalcone B results in increased expression of MIR4508 mRNA

NCBI chr15:23,562,062...23,562,131
Ensembl chr15:23,562,062...23,562,131

G

microRNA 451a

increases expression

EXP

licochalcone B results in increased expression of MIR451A mRNA

NCBI chr17:28,861,369...28,861,440
Ensembl chr17:28,861,369...28,861,440

G

microRNA 4521

decreases expression

EXP

licochalcone B results in decreased expression of MIR4521 mRNA

NCBI chr17:8,186,945...8,187,004
Ensembl chr17:8,186,945...8,187,004

G

microRNA 484

decreases expression

EXP

licochalcone B results in decreased expression of MIR484 mRNA

NCBI chr16:15,643,294...15,643,372
Ensembl chr16:15,643,294...15,643,372

G

microRNA 5100

decreases expression

EXP

licochalcone B results in decreased expression of MIR5100 mRNA

NCBI chr10:42,997,563...42,997,681
Ensembl chr10:42,997,563...42,997,681

G

microRNA 548u

increases expression

EXP

licochalcone B results in increased expression of MIR548U mRNA

NCBI chr 6:57,390,132...57,390,212
Ensembl chr 6:57,390,132...57,390,212

G

microRNA 576

increases expression

EXP

licochalcone B results in increased expression of MIR576 mRNA

NCBI chr 4:109,488,698...109,488,795
Ensembl chr 4:109,488,698...109,488,795

G

microRNA 615

decreases expression

EXP

licochalcone B results in decreased expression of MIR615 mRNA

NCBI chr12:54,033,950...54,034,045
Ensembl chr12:54,033,950...54,034,045

G

microRNA 663a

increases expression

EXP

licochalcone B results in increased expression of MIR663A mRNA

NCBI chr20:26,208,186...26,208,278
Ensembl chr20:26,208,186...26,208,278

G

microRNA 671

decreases expression

EXP

licochalcone B results in decreased expression of MIR671 mRNA

NCBI chr 7:151,238,421...151,238,538
Ensembl chr 7:151,238,421...151,238,538

G

microRNA 675

decreases expression

EXP

licochalcone B results in decreased expression of MIR675 mRNA

NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831

G

microRNA 760

decreases expression

EXP

licochalcone B results in decreased expression of MIR760 mRNA

NCBI chr 1:93,846,832...93,846,911
Ensembl chr 1:93,846,832...93,846,911

G

microRNA 7704

increases expression

EXP

licochalcone B results in increased expression of MIR7704 mRNA

NCBI chr 2:176,188,843...176,188,901
Ensembl chr 2:176,188,843...176,188,901

G

microRNA 7974

decreases expression

EXP

licochalcone B results in decreased expression of MIR7974 mRNA

NCBI chr19:11,495,544...11,495,622
Ensembl chr19:11,495,544...11,495,622

G

microRNA 7977

decreases expression

EXP

licochalcone B results in decreased expression of MIR7977 mRNA

NCBI chr 3:176,515,103...176,515,151
Ensembl chr 3:176,515,103...176,515,151

G

microRNA 874

decreases expression

EXP

licochalcone B results in decreased expression of MIR874 mRNA

NCBI chr 5:137,647,572...137,647,649
Ensembl chr 5:137,647,572...137,647,649

G

microRNA 92a-1

decreases expression

EXP

licochalcone B results in decreased expression of MIR92A1 mRNA

NCBI chr13:91,351,314...91,351,391
Ensembl chr13:91,351,314...91,351,391

G

microRNA 96

increases expression

EXP

licochalcone B results in increased expression of MIR96 mRNA

NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769

G

microRNA let-7c

decreases expression

EXP

licochalcone B results in decreased expression of MIRLET7C mRNA

NCBI chr21:16,539,828...16,539,911
Ensembl chr21:16,539,828...16,539,911

G

microRNA let-7e

decreases expression

EXP

licochalcone B results in decreased expression of MIRLET7E mRNA

NCBI chr19:51,692,786...51,692,864
Ensembl chr19:51,692,786...51,692,864

G

MKRN2 opposite strand

decreases expression

EXP

licochalcone B results in decreased expression of MKRN2OS mRNA

NCBI chr 3:12,539,776...12,560,999
Ensembl chr 3:12,514,934...12,561,059

G

MN1 proto-oncogene, transcriptional regulator

decreases expression

EXP

licochalcone B results in decreased expression of MN1 mRNA

NCBI chr22:27,748,277...27,801,756
Ensembl chr22:27,748,277...27,801,756

G

meiosis specific nuclear structural 1

decreases expression

EXP

licochalcone B results in decreased expression of MNS1 mRNA

NCBI chr15:56,428,724...56,465,137
Ensembl chr15:56,421,544...56,465,168

G

megakaryocyte and platelet inhibitory receptor G6b

increases expression

EXP

licochalcone B results in increased expression of MPIG6B mRNA

NCBI chr 6:31,720,296...31,726,714
Ensembl chr 6:31,718,594...31,726,714

G

mitochondrial ribosomal protein L18

increases expression

EXP

licochalcone B results in increased expression of MRPL18 mRNA

NCBI chr 6:159,789,812...159,798,429
Ensembl chr 6:159,789,812...159,799,027

G

mitochondrial ribosomal protein S24

increases expression

EXP

licochalcone B results in increased expression of MRPS24 mRNA

NCBI chr 7:43,866,558...43,869,517
Ensembl chr 7:43,866,557...43,869,893

G

myocardin related transcription factor B

decreases expression

EXP

licochalcone B results in decreased expression of MRTFB mRNA

NCBI chr16:13,994,774...14,266,779
Ensembl chr16:14,071,058...14,266,778

G

membrane spanning 4-domains A4E

increases expression

EXP

licochalcone B results in increased expression of MS4A4E mRNA

NCBI chr11:60,200,270...60,243,137
Ensembl chr11:60,200,270...60,243,137

G

msh homeobox 1

increases expression

EXP

licochalcone B results in increased expression of MSX1 mRNA

NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936

G

mitochondrially encoded ATP synthase membrane subunit 8

decreases expression

EXP

licochalcone B results in decreased expression of ATP8 mRNA

NCBI chr MT:8,366...8,572
Ensembl chr MT:8,366...8,572

G

mitochondrially encoded cytochrome c oxidase I

decreases expression

EXP

licochalcone B results in decreased expression of COX1 mRNA

NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445

G

mitochondrially encoded cytochrome c oxidase III

decreases expression

EXP

licochalcone B results in decreased expression of COX3 mRNA

NCBI chr MT:9,207...9,990
Ensembl chr MT:9,207...9,990

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

decreases expression

EXP

licochalcone B results in decreased expression of ND2 mRNA

NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3

decreases expression

EXP

licochalcone B results in decreased expression of ND3 mRNA

NCBI chr MT:10,059...10,404
Ensembl chr MT:10,059...10,404

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4

decreases expression

EXP

licochalcone B results in decreased expression of ND4 mRNA

NCBI chr MT:10,760...12,137
Ensembl chr MT:10,760...12,137

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L

decreases expression

EXP

licochalcone B results in decreased expression of ND4L mRNA

NCBI chr MT:10,470...10,766
Ensembl chr MT:10,470...10,766

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

decreases expression

EXP

licochalcone B results in decreased expression of ND5 mRNA

NCBI chr MT:12,337...14,148
Ensembl chr MT:12,337...14,148

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

decreases expression

EXP

licochalcone B results in decreased expression of ND6 mRNA

NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673

G

mucin 20, cell surface associated

increases expression

EXP

licochalcone B results in increased expression of MUC20 mRNA

NCBI chr 3:195,720,978...195,733,551
Ensembl chr 3:195,720,884...195,741,123

G

mucin 6, oligomeric mucus/gel-forming (gene/pseudogene)

decreases expression

EXP

licochalcone B results in decreased expression of MUC6 mRNA

NCBI chr11:1,012,823...1,036,718
Ensembl chr11:1,012,823...1,036,718

G

MAX dimerization protein 1

increases expression

EXP

licochalcone B results in increased expression of MXD1 mRNA

NCBI chr 2:69,915,109...69,942,945
Ensembl chr 2:69,897,688...69,942,945

G

MYCL proto-oncogene, bHLH transcription factor

increases expression

EXP

licochalcone B results in increased expression of MYCL mRNA

NCBI chr 1:39,895,428...39,901,917
Ensembl chr 1:39,895,428...39,902,256

G

myosin regulatory light chain interacting protein

increases expression

EXP

licochalcone B results in increased expression of MYLIP mRNA

NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,151,367

G

myosin XVA

increases expression

EXP

licochalcone B results in increased expression of MYO15A mRNA

NCBI chr17:18,108,756...18,179,800
Ensembl chr17:18,108,756...18,179,802

G

myelin transcription factor 1 like

decreases expression

EXP

licochalcone B results in decreased expression of MYT1L mRNA

NCBI chr 2:1,789,113...2,331,275
Ensembl chr 2:1,789,113...2,331,664

G

NEDD4 binding protein 2 like 1

increases expression

EXP

licochalcone B results in increased expression of N4BP2L1 mRNA

NCBI chr13:32,400,723...32,429,615
Ensembl chr13:32,400,723...32,428,311

G

nuclear apoptosis inducing factor 1

increases expression

EXP

licochalcone B results in increased expression of NAIF1 mRNA

NCBI chr 9:128,061,233...128,067,320
Ensembl chr 9:128,061,233...128,068,206

G

nanos C2HC-type zinc finger 1

increases expression

EXP

licochalcone B results in increased expression of NANOS1 mRNA

NCBI chr10:119,029,714...119,033,730
Ensembl chr10:119,029,714...119,033,730

G

NCCRP1, F-box associated domain containing

decreases expression

EXP

licochalcone B results in decreased expression of NCCRP1 mRNA

NCBI chr19:39,196,964...39,201,884
Ensembl chr19:39,196,964...39,201,884

G

NCK associated protein 5 like

increases expression

EXP

licochalcone B results in increased expression of NCKAP5L mRNA

NCBI chr12:49,791,152...49,828,413
Ensembl chr12:49,791,140...49,828,750

G

N-terminal EF-hand calcium binding protein 1

increases expression

EXP

licochalcone B results in increased expression of NECAB1 mRNA

NCBI chr 8:90,791,775...90,959,393
Ensembl chr 8:90,791,741...90,959,393

G

neuraminidase 1

increases expression

EXP

licochalcone B results in increased expression of NEU1 mRNA

NCBI chr 6:31,857,659...31,862,821
Ensembl chr 6:31,857,063...31,862,905

G

neuraminidase 4

decreases expression

EXP

licochalcone B results in decreased expression of NEU4 mRNA

NCBI chr 2:241,809,193...241,817,413
Ensembl chr 2:241,808,982...241,817,415

G

neuralized E3 ubiquitin protein ligase 1B

decreases expression

EXP

licochalcone B results in decreased expression of NEURL1B mRNA

NCBI chr 5:172,641,263...172,691,540
Ensembl chr 5:172,641,248...172,691,540

G

nuclear factor of activated T cells 1

increases expression

EXP

licochalcone B results in increased expression of NFATC1 mRNA

NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325

G

NFKB inhibitor alpha

multiple interactions

ISO

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

NFKB inhibitor delta

increases expression

EXP

licochalcone B results in increased expression of NFKBID mRNA

NCBI chr19:35,887,952...35,902,303
Ensembl chr19:35,887,630...35,902,303

G

NFKB inhibitor zeta

increases expression

EXP

licochalcone B results in increased expression of NFKBIZ mRNA

NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022

G

nerve growth factor receptor

increases expression

EXP

licochalcone B results in increased expression of NGFR mRNA

NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008

G

nescient helix-loop-helix 1

increases expression

EXP

licochalcone B results in increased expression of NHLH1 mRNA

NCBI chr 1:160,367,071...160,372,846
Ensembl chr 1:160,367,071...160,372,846

G

niban apoptosis regulator 3

increases expression

EXP

licochalcone B results in increased expression of NIBAN3 mRNA

NCBI chr19:17,523,301...17,555,537
Ensembl chr19:17,523,301...17,553,839

G

nidogen 2

increases expression

EXP

licochalcone B results in increased expression of NID2 mRNA

NCBI chr14:52,004,809...52,069,059
Ensembl chr14:52,004,809...52,069,059

G

NK2 homeobox 5

increases expression

EXP

licochalcone B results in increased expression of NKX2-5 mRNA

NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311

G

NK3 homeobox 1

increases expression

EXP

licochalcone B results in increased expression of NKX3-1 mRNA

NCBI chr 8:23,678,693...23,682,938
Ensembl chr 8:23,678,697...23,682,938

G

NLR family CARD domain containing 3

decreases expression

EXP

licochalcone B results in decreased expression of NLRC3 mRNA

NCBI chr16:3,539,033...3,577,403
Ensembl chr16:3,539,033...3,577,403

G

neuromedin B

increases expression

EXP

licochalcone B results in increased expression of NMB mRNA

NCBI chr15:84,655,132...84,658,199
Ensembl chr15:84,655,129...84,658,563

G

nicotinamide riboside kinase 2

increases expression

EXP

licochalcone B results in increased expression of NMRK2 mRNA

NCBI chr19:3,933,069...3,942,416
Ensembl chr19:3,932,994...3,943,081

G

neuronatin

increases expression

EXP

licochalcone B results in increased expression of NNAT mRNA

NCBI chr20:37,521,250...37,523,690
Ensembl chr20:37,521,206...37,523,690

G

nocturnin

increases expression

EXP

licochalcone B results in increased expression of NOCT mRNA

NCBI chr 4:139,015,781...139,045,939
Ensembl chr 4:139,015,772...139,045,939

G

nitric oxide synthase 2

multiple interactions

ISO

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]

NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,758

G

notch receptor 1

increases expression

EXP

licochalcone B results in increased expression of NOTCH1 mRNA

NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048

G

notch receptor 4

increases expression

EXP

licochalcone B results in increased expression of NOTCH4 mRNA

NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,111

G

NPHS1 adhesion molecule, nephrin

increases expression

EXP

licochalcone B results in increased expression of NPHS1 mRNA

NCBI chr19:35,825,372...35,852,504
Ensembl chr19:35,825,372...35,869,287

G

neuropeptide Y receptor Y4

decreases expression

EXP

licochalcone B results in decreased expression of NPY4R mRNA

NCBI chr10:46,461,099...46,470,668
Ensembl chr10:46,457,895...46,465,958

G

neuropeptide Y receptor Y4-2

decreases expression

EXP

licochalcone B results in decreased expression of NPY4R2 mRNA

NCBI chr10:47,914,243...47,923,524
Ensembl chr10:47,918,662...47,925,736

G

nuclear receptor subfamily 1 group I member 3

decreases expression

EXP

licochalcone B results in decreased expression of NR1I3 mRNA

NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,262

G

NOTCH regulated ankyrin repeat protein

increases expression

EXP

licochalcone B results in increased expression of NRARP mRNA

NCBI chr 9:137,299,631...137,302,271
Ensembl chr 9:137,299,631...137,302,271

G

neuronal regeneration related protein

decreases expression

EXP

licochalcone B results in decreased expression of NREP mRNA

NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464

G

neurotensin receptor 1

decreases expression

EXP

licochalcone B results in decreased expression of NTSR1 mRNA

NCBI chr20:62,708,836...62,762,771
Ensembl chr20:62,708,836...62,762,771

G

nudix hydrolase 12

decreases expression

EXP

licochalcone B results in decreased expression of NUDT12 mRNA

NCBI chr 5:103,548,855...103,562,789
Ensembl chr 5:103,548,855...103,562,806

G

nuclear GTPase, germinal center associated

increases expression

EXP

licochalcone B results in increased expression of NUGGC mRNA

NCBI chr 8:28,021,964...28,083,936
Ensembl chr 8:28,021,964...28,083,936

G

nuclear RNA export factor 1

increases expression

EXP

licochalcone B results in increased expression of NXF1 mRNA

NCBI chr11:62,792,130...62,805,440
Ensembl chr11:62,792,123...62,806,302

G

ornithine aminotransferase

increases expression

EXP

licochalcone B results in increased expression of OAT mRNA

NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,298...124,419,760

G

olfactory receptor family 2 subfamily B member 6

increases expression

EXP

licochalcone B results in increased expression of OR2B6 mRNA

NCBI chr 6:27,957,241...27,958,182
Ensembl chr 6:27,957,241...27,958,182

G

oxidative stress responsive serine rich 1

increases expression

EXP

licochalcone B results in increased expression of OSER1 mRNA

NCBI chr20:44,195,939...44,211,810
Ensembl chr20:44,195,939...44,210,872

G

oxidative stress induced growth inhibitor 1

increases expression

EXP

licochalcone B results in increased expression of OSGIN1 mRNA

NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,333

G

odd-skipped related transciption factor 2

increases expression

EXP

licochalcone B results in increased expression of OSR2 mRNA

NCBI chr 8:98,944,442...98,952,100
Ensembl chr 8:98,940,116...98,952,336

G

OTU deubiquitinase 5

increases expression

EXP

licochalcone B results in increased expression of OTUD5 mRNA

NCBI chr X:48,922,024...48,958,381
Ensembl chr X:48,922,024...48,958,386

G

OTU deubiquitinase with linear linkage specificity like

decreases expression

EXP

licochalcone B results in decreased expression of OTULINL mRNA

NCBI chr 5:14,581,792...14,616,180
Ensembl chr 5:14,581,792...14,616,180

G

pyrimidinergic receptor P2Y6

decreases expression

EXP

licochalcone B results in decreased expression of P2RY6 mRNA

NCBI chr11:73,264,506...73,298,625
Ensembl chr11:73,264,498...73,305,103

G

poly(A) binding protein cytoplasmic 4 like

decreases expression

EXP

licochalcone B results in decreased expression of PABPC4L mRNA

NCBI chr 4:133,948,459...134,201,901
Ensembl chr 4:134,196,333...134,201,885

G

peptidyl arginine deiminase 2

decreases expression

EXP

licochalcone B results in decreased expression of PADI2 mRNA

NCBI chr 1:17,066,761...17,119,451
Ensembl chr 1:17,066,761...17,119,459

G

palmdelphin

decreases expression

EXP

licochalcone B results in decreased expression of PALMD mRNA

NCBI chr 1:99,646,113...99,694,535
Ensembl chr 1:99,645,499...99,695,178

G

poly(ADP-ribose) polymerase 1

multiple interactions
increases cleavage

EXP

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [licochalcone B results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [licochalcone B results in increased expression of PARP1 protein]; TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of PARP1 protein]

NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154

G

poly(ADP-ribose) polymerase family member 9

decreases expression

EXP

licochalcone B results in decreased expression of PARP9 mRNA

NCBI chr 3:122,527,924...122,564,784
Ensembl chr 3:122,527,910...122,565,478

G

protocadherin beta 10

decreases expression

EXP

licochalcone B results in decreased expression of PCDHB10 mRNA

NCBI chr 5:141,192,353...141,195,647
Ensembl chr 5:141,192,353...141,195,647

G

protocadherin beta 12

decreases expression

EXP

licochalcone B results in decreased expression of PCDHB12 mRNA

NCBI chr 5:141,208,719...141,212,571
Ensembl chr 5:141,208,697...141,212,571

G

protocadherin beta 13

decreases expression

EXP

licochalcone B results in decreased expression of PCDHB13 mRNA

NCBI chr 5:141,213,919...141,218,979
Ensembl chr 5:141,213,919...141,218,979

G

protocadherin beta 16

decreases expression

EXP

licochalcone B results in decreased expression of PCDHB16 mRNA

NCBI chr 5:141,182,387...141,186,226
Ensembl chr 5:141,182,387...141,186,226

G

protocadherin gamma subfamily A, 1

decreases expression

EXP

licochalcone B results in decreased expression of PCDHGA1 mRNA

NCBI chr 5:141,330,514...141,512,975
Ensembl chr 5:141,330,514...141,512,975

G

protocadherin gamma subfamily A, 10

decreases expression

EXP

licochalcone B results in decreased expression of PCDHGA10 mRNA

NCBI chr 5:141,412,987...141,512,975
Ensembl chr 5:141,412,987...141,512,975

G

proprotein convertase subtilisin/kexin type 1

decreases expression

EXP

licochalcone B results in decreased expression of PCSK1 mRNA

NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143

G

phosphodiesterase 3A

decreases expression

EXP

licochalcone B results in decreased expression of PDE3A mRNA

NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583

G

platelet derived growth factor subunit A

increases expression

EXP

licochalcone B results in increased expression of PDGFA mRNA

NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,695

G

platelet derived growth factor subunit B

decreases expression

EXP

licochalcone B results in decreased expression of PDGFB mRNA

NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982

G

proliferation and apoptosis adaptor protein 15

increases expression

EXP

licochalcone B results in increased expression of PEA15 mRNA

NCBI chr 1:160,205,384...160,215,372
Ensembl chr 1:160,205,335...160,215,404

G

PEAK family member 3

increases expression

EXP

licochalcone B results in increased expression of PEAK3 mRNA

NCBI chr19:2,274,631...2,282,175
Ensembl chr19:2,274,631...2,282,175

G

piggyBac transposable element derived 2

increases expression

EXP

licochalcone B results in increased expression of PGBD2 mRNA

NCBI chr 1:248,872,851...248,930,191
Ensembl chr 1:248,906,196...248,919,946

G

placental growth factor

increases expression

EXP

licochalcone B results in increased expression of PGF mRNA

NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,830...74,955,626

G

PH domain containing endocytic trafficking adaptor 1

increases expression

EXP

licochalcone B results in increased expression of PHETA1 mRNA

NCBI chr12:111,360,679...111,369,095
Ensembl chr12:111,360,651...111,369,173

G

phosphorylase kinase catalytic subunit gamma 1

increases expression

EXP

licochalcone B results in increased expression of PHKG1 mRNA

NCBI chr 7:56,080,295...56,092,952
Ensembl chr 7:56,079,923...56,093,012

G

pleckstrin homology like domain family A member 2

increases expression

EXP

licochalcone B results in increased expression of PHLDA2 mRNA

NCBI chr11:2,928,273...2,929,420
Ensembl chr11:2,928,273...2,929,420

G

pleckstrin homology like domain family B member 2

decreases expression

EXP

licochalcone B results in decreased expression of PHLDB2 mRNA

NCBI chr 3:111,732,496...111,976,517
Ensembl chr 3:111,732,403...111,976,837

G

phytanoyl-CoA dioxygenase domain containing 1

increases expression

EXP

licochalcone B results in increased expression of PHYHD1 mRNA

NCBI chr 9:128,920,982...128,942,041
Ensembl chr 9:128,920,966...128,942,042

G

paired immunoglobin like type 2 receptor alpha

increases expression

EXP

licochalcone B results in increased expression of PILRA mRNA

NCBI chr 7:100,371,291...100,400,096
Ensembl chr 7:100,367,530...100,400,096

G

paired immunoglobin like type 2 receptor beta

increases expression

EXP

licochalcone B results in increased expression of PILRB mRNA

NCBI chr 7:100,358,117...100,367,831
Ensembl chr 7:100,352,176...100,367,831

G

PITH domain containing 1

increases expression

EXP

licochalcone B results in increased expression of PITHD1 mRNA

NCBI chr 1:23,778,418...23,788,232
Ensembl chr 1:23,778,393...23,788,232

G

polycystin 1 like 1, transient receptor potential channel interacting

increases expression

EXP

licochalcone B results in increased expression of PKD1L1 mRNA

NCBI chr 7:47,774,614...47,960,906
Ensembl chr 7:47,740,202...47,948,466

G

polycystin 1 like 3, transient receptor potential channel interacting

increases expression

EXP

licochalcone B results in increased expression of PKD1L3 mRNA

NCBI chr16:71,929,538...72,000,402
Ensembl chr16:71,929,538...72,000,402

G

phospholipase A2 group IVA

decreases expression

EXP

licochalcone B results in decreased expression of PLA2G4A mRNA

NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,986

G

PLAC8 like 1

increases expression

EXP

licochalcone B results in increased expression of PLAC8L1 mRNA

NCBI chr 5:146,084,313...146,105,577
Ensembl chr 5:146,084,313...146,105,577

G

phosphatidylinositol specific phospholipase C X domain containing 1

increases expression

EXP

licochalcone B results in increased expression of PLCXD1 mRNA

NCBI chr  X:276,356...303,356
NCBI chr  Y:276,356...303,356
Ensembl chr  X:276,322...303,358
Ensembl chr  Y:276,322...303,358

G

phospholipase D1

decreases expression

EXP

licochalcone B results in decreased expression of PLD1 mRNA

NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950

G

pleckstrin

increases expression

EXP

licochalcone B results in increased expression of PLEK mRNA

NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453

G

pleckstrin homology domain containing A2

decreases expression

EXP

licochalcone B results in decreased expression of PLEKHA2 mRNA

NCBI chr 8:38,901,346...38,973,912
Ensembl chr 8:38,901,235...38,973,912

G

pleckstrin homology and RhoGEF domain containing G6

decreases expression

EXP

licochalcone B results in decreased expression of PLEKHG6 mRNA

NCBI chr12:6,310,332...6,328,506
Ensembl chr12:6,310,225...6,328,934

G

pleckstrin homology domain containing O2

increases expression

EXP

licochalcone B results in increased expression of PLEKHO2 mRNA

NCBI chr15:64,841,915...64,868,002
Ensembl chr15:64,839,231...64,868,002

G

perilipin 2

increases expression

EXP

licochalcone B results in increased expression of PLIN2 mRNA

NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,369

G

perilipin 5

increases expression

EXP

licochalcone B results in increased expression of PLIN5 mRNA

NCBI chr19:4,522,531...4,535,224
Ensembl chr19:4,522,531...4,535,247

G

polo like kinase 2

increases expression

EXP

licochalcone B results in increased expression of PLK2 mRNA

NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139

G

polo like kinase 3

increases expression

EXP

licochalcone B results in increased expression of PLK3 mRNA

NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,346...44,805,995

G

polo like kinase 5 (inactive)

increases expression

EXP

licochalcone B results in increased expression of PLK5 mRNA

NCBI chr19:1,524,077...1,536,046
Ensembl chr19:1,508,023...1,536,046

G

phospholipid phosphatase related 3

increases expression

EXP

licochalcone B results in increased expression of PLPPR3 mRNA

NCBI chr19:812,488...823,797
Ensembl chr19:812,487...822,619

G

plasmalemma vesicle associated protein

increases expression

EXP

licochalcone B results in increased expression of PLVAP mRNA

NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,356

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

EXP

licochalcone B results in increased expression of PMAIP1 mRNA

NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,644...59,904,305

G

pregnancy up-regulated nonubiquitous CaM kinase

increases expression

EXP

licochalcone B results in increased expression of PNCK mRNA

NCBI chr X:153,669,733...153,687,771
Ensembl chr X:153,669,730...153,689,033

G

PARN like ribonuclease domain containing exonuclease 1

increases expression

EXP

licochalcone B results in increased expression of PNLDC1 mRNA

NCBI chr 6:159,799,455...159,820,704
Ensembl chr 6:159,800,249...159,820,704

G

patatin like phospholipase domain containing 2

increases expression

EXP

licochalcone B results in increased expression of PNPLA2 mRNA

NCBI chr11:818,914...825,573
Ensembl chr11:818,914...825,573

G

proline rich nuclear receptor coactivator 1

increases expression

EXP

licochalcone B results in increased expression of PNRC1 mRNA

NCBI chr 6:89,080,751...89,085,160
Ensembl chr 6:89,080,751...89,085,160

G

podocan like 1

increases expression

EXP

licochalcone B results in increased expression of PODNL1 mRNA

NCBI chr19:13,931,187...13,953,383
Ensembl chr19:13,931,183...13,953,392

G

POTE ankyrin domain family member F

decreases expression

EXP

licochalcone B results in decreased expression of POTEF mRNA

NCBI chr 2:130,073,535...130,129,222
Ensembl chr 2:130,073,535...130,129,222

G

POU class 3 homeobox 1

increases expression

EXP

licochalcone B results in increased expression of POU3F1 mRNA

NCBI chr 1:38,043,829...38,046,793
Ensembl chr 1:38,043,829...38,046,793

G

protein phosphatase with EF-hand domain 1

decreases expression

EXP

licochalcone B results in decreased expression of PPEF1 mRNA

NCBI chr X:18,675,067...18,827,917
Ensembl chr X:18,675,909...18,827,921

G

protein phosphatase 1 regulatory subunit 13B

increases expression

EXP

licochalcone B results in increased expression of PPP1R13B mRNA

NCBI chr14:103,733,195...103,848,814
Ensembl chr14:103,733,195...103,847,614

G

protein phosphatase 1 regulatory subunit 15A

increases expression

EXP

licochalcone B results in increased expression of PPP1R15A mRNA

NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,291

G

protein phosphatase 1 regulatory subunit 27

increases expression

EXP

licochalcone B results in increased expression of PPP1R27 mRNA

NCBI chr17:81,833,492...81,835,050
Ensembl chr17:81,833,488...81,835,050

G

proline rich 18

increases expression

EXP

licochalcone B results in increased expression of PRR18 mRNA

NCBI chr 6:166,305,300...166,308,392
Ensembl chr 6:166,305,300...166,308,448

G

prostaglandin E receptor 1

increases expression

EXP

licochalcone B results in increased expression of PTGER1 mRNA

NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,477,272

G

PX domain containing 1

increases expression

EXP

licochalcone B results in increased expression of PXDC1 mRNA

NCBI chr 6:3,722,619...3,751,713
Ensembl chr 6:3,722,614...3,751,713

G

glycogen phosphorylase, muscle associated

increases expression

EXP

licochalcone B results in increased expression of PYGM mRNA

NCBI chr11:64,746,389...64,760,715
Ensembl chr11:64,746,389...64,759,974

G

PZP alpha-2-macroglobulin like

decreases expression

EXP

licochalcone B results in decreased expression of PZP mRNA

NCBI chr12:9,136,472...9,208,395
Ensembl chr12:9,148,840...9,208,399

G

RAB33A, member RAS oncogene family

increases expression

EXP

licochalcone B results in increased expression of RAB33A mRNA

NCBI chr X:130,110,623...130,184,870
Ensembl chr X:130,171,950...130,184,874

G

RAD9 checkpoint clamp component B

increases expression

EXP

licochalcone B results in increased expression of RAD9B mRNA

NCBI chr12:110,502,331...110,533,556
Ensembl chr12:110,501,655...110,533,556

G

Rap associating with DIL domain

increases expression

EXP

licochalcone B results in increased expression of RADIL mRNA

NCBI chr 7:4,797,055...4,883,716
Ensembl chr 7:4,797,055...4,883,716

G

retinoic acid receptor responder 2

decreases expression

EXP

licochalcone B results in decreased expression of RARRES2 mRNA

NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,314...150,342,144

G

ras related dexamethasone induced 1

increases expression

EXP

licochalcone B results in increased expression of RASD1 mRNA

NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,396

G

RAS like family 10 member A

increases expression

EXP

licochalcone B results in increased expression of RASL10A mRNA

NCBI chr22:29,312,933...29,319,859
Ensembl chr22:29,312,933...29,319,679

G

RAS like family 11 member A

increases expression

EXP

licochalcone B results in increased expression of RASL11A mRNA

NCBI chr13:27,270,830...27,275,192
Ensembl chr13:27,270,810...27,275,192

G

Ras association domain family member 2

decreases expression

EXP

licochalcone B results in decreased expression of RASSF2 mRNA

NCBI chr20:4,780,023...4,823,608
Ensembl chr20:4,780,019...4,823,870

G

Ras association domain family member 9

decreases expression

EXP

licochalcone B results in decreased expression of RASSF9 mRNA

NCBI chr12:85,800,703...85,836,409
Ensembl chr12:85,800,703...85,836,409

G

RNA binding fox-1 homolog 3

increases expression

EXP

licochalcone B results in increased expression of RBFOX3 mRNA

NCBI chr17:79,089,345...79,665,571
Ensembl chr17:79,089,345...79,611,258

G

RNA binding motif protein 38

increases expression

EXP

licochalcone B results in increased expression of RBM38 mRNA

NCBI chr20:57,391,396...57,409,333
Ensembl chr20:57,391,396...57,409,333

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

licochalcone B analog inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]

NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090

G

RELB proto-oncogene, NF-kB subunit

increases expression

EXP

licochalcone B results in increased expression of RELB mRNA

NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192

G

RELT like 2

increases expression

EXP

licochalcone B results in increased expression of RELL2 mRNA

NCBI chr 5:141,636,997...141,641,064
Ensembl chr 5:141,636,950...141,641,064

G

RELT TNF receptor

increases expression

EXP

licochalcone B results in increased expression of RELT mRNA

NCBI chr11:73,376,399...73,397,474
Ensembl chr11:73,376,325...73,397,474

G

raftlin family member 2

increases expression

EXP

licochalcone B results in increased expression of RFTN2 mRNA

NCBI chr 2:197,568,224...197,675,587
Ensembl chr 2:197,568,224...197,676,051

G

regulator of cell cycle

increases expression

EXP

licochalcone B results in increased expression of RGCC mRNA

NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,532...41,470,877

G

repulsive guidance molecule BMP co-receptor a

increases expression

EXP

licochalcone B results in increased expression of RGMA mRNA

NCBI chr15:93,035,271...93,089,211
Ensembl chr15:93,035,271...93,089,211

G

regulator of G protein signaling 16

increases expression

EXP

licochalcone B results in increased expression of RGS16 mRNA

NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,394

G

regulator of G protein signaling 9 binding protein

decreases expression

EXP

licochalcone B results in decreased expression of RGS9BP mRNA

NCBI chr19:32,675,848...32,678,300
Ensembl chr19:32,675,848...32,678,300

G

Rh blood group CcEe antigens

increases expression

EXP

licochalcone B results in increased expression of RHCE mRNA

NCBI chr 1:25,362,249...25,430,203
Ensembl chr 1:25,362,249...25,430,192

G

RIB43A domain with coiled-coils 2

decreases expression

EXP

licochalcone B results in decreased expression of RIBC2 mRNA

NCBI chr22:45,413,693...45,432,509
Ensembl chr22:45,413,693...45,432,509

G

RIPOR family member 3

increases expression

EXP

licochalcone B results in increased expression of RIPOR3 mRNA

NCBI chr20:50,586,108...50,691,542
Ensembl chr20:50,585,180...50,692,021

G

Rho family GTPase 1

increases expression

EXP

licochalcone B results in increased expression of RND1 mRNA

NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870

G

RNF103-CHMP3 readthrough

increases expression

EXP

licochalcone B results in increased expression of RNF103-CHMP3 mRNA

NCBI chr 2:86,503,430...86,721,122
Ensembl chr 2:86,505,668...86,721,122

G

ring finger protein 150

decreases expression

EXP

licochalcone B results in decreased expression of RNF150 mRNA

NCBI chr 4:140,859,807...141,212,900
Ensembl chr 4:140,859,807...141,212,877

G

ring finger protein 19B

increases expression

EXP

licochalcone B results in increased expression of RNF19B mRNA

NCBI chr 1:32,929,036...32,964,809
Ensembl chr 1:32,929,036...32,964,915

G

ring finger protein 225

increases expression

EXP

licochalcone B results in increased expression of RNF225 mRNA

NCBI chr19:58,395,656...58,397,079
Ensembl chr19:58,395,656...58,397,079

G

ring finger protein 227

increases expression

EXP

licochalcone B results in increased expression of RNF227 mRNA

NCBI chr17:7,913,324...7,916,318
Ensembl chr17:7,913,339...7,916,289

G

ring finger protein 31

increases expression

EXP

licochalcone B results in increased expression of RNF31 mRNA

NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660

G

RAR related orphan receptor B

decreases expression

EXP

licochalcone B results in decreased expression of RORB mRNA

NCBI chr 9:74,497,335...74,693,177
Ensembl chr 9:74,497,335...74,693,177

G

RP1 like 1

decreases expression

EXP

licochalcone B results in decreased expression of RP1L1 mRNA

NCBI chr 8:10,606,349...10,655,143
Ensembl chr 8:10,606,349...10,712,187

G

ribosomal protein S6 kinase A2

decreases expression

EXP

licochalcone B results in decreased expression of RPS6KA2 mRNA

NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451

G

ribosomal protein S6 kinase B1

decreases phosphorylation

EXP

licochalcone B results in decreased phosphorylation of RPS6KB1 protein

NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

EXP

licochalcone B results in increased expression of RRAD mRNA

NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,682...66,926,308

G

radial spoke head 6 homolog A

increases expression

EXP

licochalcone B results in increased expression of RSPH6A mRNA

NCBI chr19:45,795,713...45,815,308
Ensembl chr19:45,795,713...45,815,308

G

arginine and serine rich protein 1

increases expression

EXP

licochalcone B results in increased expression of RSRP1 mRNA

NCBI chr 1:25,242,249...25,338,254
Ensembl chr 1:25,242,248...25,338,244

G

RUNX family transcription factor 2

decreases expression

EXP

licochalcone B results in decreased expression of RUNX2 mRNA

NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349

G

S100 calcium binding protein A1

increases expression

EXP

licochalcone B results in increased expression of S100A1 mRNA

NCBI chr 1:153,628,434...153,632,039
Ensembl chr 1:153,627,926...153,632,044

G

sterile alpha motif domain containing 5

decreases expression

EXP

licochalcone B results in decreased expression of SAMD5 mRNA

NCBI chr 6:147,508,690...147,954,680
Ensembl chr 6:147,508,690...147,737,547

G

sterile alpha motif domain containing 9

decreases expression

EXP

licochalcone B results in decreased expression of SAMD9 mRNA

NCBI chr 7:93,099,518...93,117,979
Ensembl chr 7:93,099,513...93,118,023

G

spermidine/spermine N1-acetyltransferase 1

increases expression

EXP

licochalcone B results in increased expression of SAT1 mRNA

NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210

G

stabilizer of axonemal microtubules 4

increases expression

EXP

licochalcone B results in increased expression of SAXO4 mRNA

NCBI chr11:61,481,120...61,490,928
Ensembl chr11:61,481,120...61,490,931

G

suprabasin

increases expression

EXP

licochalcone B results in increased expression of SBSN mRNA

NCBI chr19:35,523,367...35,528,311
Ensembl chr19:35,523,367...35,528,351

G

sodium voltage-gated channel beta subunit 3

decreases expression

EXP

licochalcone B results in decreased expression of SCN3B mRNA

NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244

G

scratch family transcriptional repressor 1

increases expression

EXP

licochalcone B results in increased expression of SCRT1 mRNA

NCBI chr 8:144,330,565...144,336,482
Ensembl chr 8:144,330,565...144,336,482

G

syndecan 4

increases expression

EXP

licochalcone B results in increased expression of SDC4 mRNA

NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,425

G

syndecan binding protein 2

increases expression

EXP

licochalcone B results in increased expression of SDCBP2 mRNA

NCBI chr20:1,309,909...1,329,139
Ensembl chr20:1,309,909...1,329,211

G

semaphorin 4A

increases expression

EXP

licochalcone B results in increased expression of SEMA4A mRNA

NCBI chr 1:156,147,373...156,177,744
Ensembl chr 1:156,147,366...156,178,869

G

semaphorin 5A

decreases expression

EXP

licochalcone B results in decreased expression of SEMA5A mRNA

NCBI chr 5:9,035,033...9,546,075
Ensembl chr 5:9,035,033...9,546,142

G

SUMO specific peptidase 3

increases expression

EXP

licochalcone B results in increased expression of SENP3 mRNA

NCBI chr17:7,561,919...7,571,969
Ensembl chr17:7,561,919...7,571,969

G

serpin family B member 8

increases expression

EXP

licochalcone B results in increased expression of SERPINB8 mRNA

NCBI chr18:63,970,081...64,019,779
Ensembl chr18:63,970,029...64,019,779

G

serpin family C member 1

increases expression

EXP

licochalcone B results in increased expression of SERPINC1 mRNA

NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,519...173,917,543

G

SERTA domain containing 1

increases expression

EXP

licochalcone B results in increased expression of SERTAD1 mRNA

NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992

G

sestrin 2

increases expression

EXP

licochalcone B results in increased expression of SESN2 mRNA

NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,473...28,282,491

G

sestrin 3

increases expression

EXP

licochalcone B results in increased expression of SESN3 mRNA

NCBI chr11:95,165,513...95,232,475
Ensembl chr11:95,165,513...95,232,541

G

stratifin

increases expression

EXP

licochalcone B results in increased expression of SFN mRNA

NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456

G

secreted frizzled related protein 5

increases expression

EXP

licochalcone B results in increased expression of SFRP5 mRNA

NCBI chr10:97,766,751...97,771,999
Ensembl chr10:97,766,751...97,771,999

G

serum/glucocorticoid regulated kinase 2

increases expression

EXP

licochalcone B results in increased expression of SGK2 mRNA

NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237

G

small G protein signaling modulator 3

increases expression

EXP

licochalcone B results in increased expression of SGSM3 mRNA

NCBI chr22:40,370,594...40,410,289
Ensembl chr22:40,370,564...40,410,289

G

SH3 domain containing 21

increases expression

EXP

licochalcone B results in increased expression of SH3D21 mRNA

NCBI chr 1:36,306,368...36,330,236
Ensembl chr 1:36,306,368...36,329,340

G

SH3 and PX domains 2A

decreases expression

EXP

licochalcone B results in decreased expression of SH3PXD2A mRNA

NCBI chr10:103,594,027...103,855,576
Ensembl chr10:103,594,027...103,855,584

G

sex hormone binding globulin

increases expression

EXP

licochalcone B results in increased expression of SHBG mRNA

NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,469

G

sirtuin 7

increases expression

EXP

licochalcone B results in increased expression of SIRT7 mRNA

NCBI chr17:81,911,939...81,918,176
Ensembl chr17:81,911,939...81,921,323

G

solute carrier family 12 member 7

decreases expression

EXP

licochalcone B results in decreased expression of SLC12A7 mRNA

NCBI chr 5:1,050,384...1,155,899
Ensembl chr 5:1,050,384...1,155,916

G

solute carrier family 13 member 4

decreases expression

EXP

licochalcone B results in decreased expression of SLC13A4 mRNA

NCBI chr 7:135,681,231...135,728,186
Ensembl chr 7:135,681,231...135,729,258

G

solute carrier family 16 member 11

increases expression

EXP

licochalcone B results in increased expression of SLC16A11 mRNA

NCBI chr17:7,041,621...7,044,092
Ensembl chr17:7,041,621...7,044,092

G

solute carrier family 16 member 6

decreases expression

EXP

licochalcone B results in decreased expression of SLC16A6 mRNA

NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267

G

solute carrier family 16 member 7

decreases expression

EXP

licochalcone B results in decreased expression of SLC16A7 mRNA

NCBI chr12:59,596,029...59,789,841
Ensembl chr12:59,596,027...59,789,855

G

solute carrier family 16 member 9

decreases expression

EXP

licochalcone B results in decreased expression of SLC16A9 mRNA

NCBI chr10:59,650,764...59,710,079
Ensembl chr10:59,650,762...59,736,002

G

solute carrier family 17 member 7

increases expression

EXP

licochalcone B results in increased expression of SLC17A7 mRNA

NCBI chr19:49,429,401...49,441,527
Ensembl chr19:49,429,399...49,443,197

G

solute carrier family 22 member 2

decreases expression

EXP

licochalcone B results in decreased expression of SLC22A2 mRNA

NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638

G

solute carrier family 25 member 25

increases expression

EXP

licochalcone B results in increased expression of SLC25A25 mRNA

NCBI chr 9:128,068,232...128,109,245
Ensembl chr 9:128,068,169...128,109,245

G

solute carrier family 39 member 4

increases expression

EXP

licochalcone B results in increased expression of SLC39A4 mRNA

NCBI chr 8:144,412,414...144,416,844
Ensembl chr 8:144,409,742...144,416,844

G

solute carrier family 44 member 4

increases expression

EXP

licochalcone B results in increased expression of SLC44A4 mRNA

NCBI chr 6:31,863,192...31,878,997
Ensembl chr 6:31,863,192...31,879,198

G

solute carrier family 5 member 5

increases expression

EXP

licochalcone B results in increased expression of SLC5A5 mRNA

NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174

G

solute carrier family 6 member 13

increases expression

EXP

licochalcone B results in increased expression of SLC6A13 mRNA

NCBI chr12:220,622...262,836
Ensembl chr12:220,621...262,873

G

solute carrier family 6 member 15

decreases expression

EXP

licochalcone B results in decreased expression of SLC6A15 mRNA

NCBI chr12:84,859,491...84,912,799
Ensembl chr12:84,859,491...84,913,629

G

solute carrier family 7 member 8

decreases expression

EXP

licochalcone B results in decreased expression of SLC7A8 mRNA

NCBI chr14:23,125,295...23,183,660
Ensembl chr14:23,125,295...23,183,674

G

solute carrier family 9 member A1

increases expression

EXP

licochalcone B results in increased expression of SLC9A1 mRNA

NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981

G

SLIT and NTRK like family member 5

decreases expression

EXP

licochalcone B results in decreased expression of SLITRK5 mRNA

NCBI chr13:87,671,371...87,679,616
Ensembl chr13:87,671,371...87,696,272

G

SLIT and NTRK like family member 6

decreases expression

EXP

licochalcone B results in decreased expression of SLITRK6 mRNA

NCBI chr13:85,792,790...85,799,419
Ensembl chr13:85,792,790...85,806,683

G

SMAD family member 7

increases expression

EXP

licochalcone B results in increased expression of SMAD7 mRNA

NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,952,020

G

SNF2 related chromatin remodeling ATPase with DExD box 1

decreases expression

EXP

licochalcone B results in decreased expression of SMARCAD1 mRNA

NCBI chr 4:94,207,608...94,291,292
Ensembl chr 4:94,207,605...94,291,293

G

snail family transcriptional repressor 1

increases expression

EXP

licochalcone B results in increased expression of SNAI1 mRNA

NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886

G

suppressor of cytokine signaling 1

increases expression

EXP

licochalcone B results in increased expression of SOCS1 mRNA

NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,249,101...11,256,556

G

suppressor of cytokine signaling 3

increases expression

EXP

licochalcone B results in increased expression of SOCS3 mRNA

NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,930

G

sorbin and SH3 domain containing 1

increases expression

EXP

licochalcone B results in increased expression of SORBS1 mRNA

NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,390...95,561,469

G

sorbin and SH3 domain containing 2

decreases expression

EXP

licochalcone B results in decreased expression of SORBS2 mRNA

NCBI chr 4:185,585,523...185,956,372
Ensembl chr 4:185,585,444...185,956,652

G

sosondowah ankyrin repeat domain family member D

increases expression

EXP

licochalcone B results in increased expression of SOWAHD mRNA

NCBI chr X:119,758,588...119,760,202
Ensembl chr X:119,758,588...119,760,202

G

SRY-box transcription factor 17

increases expression

EXP

licochalcone B results in increased expression of SOX17 mRNA

NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892

G

SRY-box transcription factor 9

increases expression

EXP

licochalcone B results in increased expression of SOX9 mRNA

NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416

G

Sp6 transcription factor

increases expression

EXP

licochalcone B results in increased expression of SP6 mRNA

NCBI chr17:47,844,908...47,876,311
Ensembl chr17:47,844,908...47,855,874

G

sperm acrosome developmental regulator

increases expression

EXP

licochalcone B results in increased expression of SPACDR mRNA

NCBI chr 7:100,456,620...100,464,260
Ensembl chr 7:100,456,620...100,464,260

G

spermatogenesis associated 2 like

increases expression

EXP

licochalcone B results in increased expression of SPATA2L mRNA

NCBI chr16:89,696,357...89,701,705
Ensembl chr16:89,696,357...89,701,705

G

SPATA31 subfamily F member 1

increases expression

EXP

licochalcone B results in increased expression of SPATA31F1 mRNA

NCBI chr 9:34,723,053...34,729,488
Ensembl chr 9:34,723,053...34,729,488

G

SPATA31 subfamily H member 1

decreases expression

EXP

licochalcone B results in decreased expression of SPATA31H1 mRNA

NCBI chr 2:27,537,386...27,582,722
Ensembl chr 2:27,537,386...27,582,722

G

speedy/RINGO cell cycle regulator family member A

increases expression

EXP

licochalcone B results in increased expression of SPDYA mRNA

NCBI chr 2:28,810,834...28,850,610
Ensembl chr 2:28,782,517...28,850,611

G

sphingosine kinase 1

increases expression

EXP

licochalcone B results in increased expression of SPHK1 mRNA

NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860

G

spindlin interactor and repressor of chromatin binding

increases expression

EXP

licochalcone B results in increased expression of SPINDOC mRNA

NCBI chr11:63,813,456...63,827,716
Ensembl chr11:63,813,433...63,827,718

G

spondin 1

increases expression

EXP

licochalcone B results in increased expression of SPON1 mRNA

NCBI chr11:13,962,723...14,268,133
Ensembl chr11:13,962,694...14,268,133

G

sprouty RTK signaling antagonist 4

increases expression

EXP

licochalcone B results in increased expression of SPRY4 mRNA

NCBI chr 5:142,310,430...142,325,021
Ensembl chr 5:142,310,420...142,326,455

G

splA/ryanodine receptor domain and SOCS box containing 1

increases expression

EXP

licochalcone B results in increased expression of SPSB1 mRNA

NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,101...9,369,532

G

splA/ryanodine receptor domain and SOCS box containing 3

increases expression

EXP

licochalcone B results in increased expression of SPSB3 mRNA

NCBI chr16:1,776,712...1,782,571
Ensembl chr16:1,776,710...1,793,700

G

serine and arginine rich splicing factor 12

increases expression

EXP

licochalcone B results in increased expression of SRSF12 mRNA

NCBI chr 6:89,095,959...89,118,071
Ensembl chr 6:89,093,949...89,118,071

G

somatostatin receptor 1

decreases expression

EXP

licochalcone B results in decreased expression of SSTR1 mRNA

NCBI chr14:38,207,904...38,213,067
Ensembl chr14:38,207,904...38,213,067

G

stanniocalcin 1

decreases expression

EXP

licochalcone B results in decreased expression of STC1 mRNA

NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806

G

STEAP4 metalloreductase

decreases expression

EXP

licochalcone B results in decreased expression of STEAP4 mRNA

NCBI chr 7:88,270,892...88,306,894
Ensembl chr 7:88,270,892...88,307,010

G

syntaxin 11

increases expression

EXP

licochalcone B results in increased expression of STX11 mRNA

NCBI chr 6:144,139,963...144,191,939
Ensembl chr 6:144,149,970...144,191,939

G

small ubiquitin like modifier 4

increases expression

EXP

licochalcone B results in increased expression of SUMO4 mRNA

NCBI chr 6:149,400,262...149,401,278
Ensembl chr 6:149,400,262...149,401,278

G

synaptic vesicle glycoprotein 2A

increases expression

EXP

licochalcone B results in increased expression of SV2A mRNA

NCBI chr 1:149,903,318...149,917,844
Ensembl chr 1:149,903,318...149,918,572

G

synaptic vesicle glycoprotein 2B

decreases expression

EXP

licochalcone B results in decreased expression of SV2B mRNA

NCBI chr15:91,099,588...91,302,565
Ensembl chr15:91,099,869...91,302,565

G

synapse differentiation inducing 1 like

increases expression

EXP

licochalcone B results in increased expression of SYNDIG1L mRNA

NCBI chr14:74,405,899...74,480,143
Ensembl chr14:74,405,894...74,426,210

G

synaptotagmin 11

increases expression

EXP

licochalcone B results in increased expression of SYT11 mRNA

NCBI chr 1:155,859,567...155,885,199
Ensembl chr 1:155,859,449...155,885,199

G

synaptotagmin like 5

decreases expression

EXP

licochalcone B results in decreased expression of SYTL5 mRNA

NCBI chr X:37,888,915...38,128,820
Ensembl chr X:38,006,515...38,128,819

G

tumor associated calcium signal transducer 2

increases expression

EXP

licochalcone B results in increased expression of TACSTD2 mRNA

NCBI chr 1:58,575,433...58,577,252
Ensembl chr 1:58,575,433...58,577,252

G

TAP binding protein like

increases expression

EXP

licochalcone B results in increased expression of TAPBPL mRNA

NCBI chr12:6,451,649...6,472,006
Ensembl chr12:6,451,690...6,466,517

G

taste 1 receptor member 1

increases expression

EXP

licochalcone B results in increased expression of TAS1R1 mRNA

NCBI chr 1:6,555,307...6,579,755
Ensembl chr 1:6,555,307...6,579,755

G

Tax1 binding protein 3

increases expression

EXP

licochalcone B results in increased expression of TAX1BP3 mRNA

NCBI chr17:3,662,895...3,668,578
Ensembl chr17:3,662,895...3,668,679

G

T-box brain transcription factor 1

increases expression

EXP

licochalcone B results in increased expression of TBR1 mRNA

NCBI chr 2:161,416,297...161,425,870
Ensembl chr 2:161,416,297...161,425,870

G

titin-cap

increases expression

EXP

licochalcone B results in increased expression of TCAP mRNA

NCBI chr17:39,665,349...39,666,554
Ensembl chr17:39,665,349...39,666,554

G

transcriptional and immune response regulator

decreases expression

EXP

licochalcone B results in decreased expression of TCIM mRNA

NCBI chr 8:40,153,482...40,155,310
Ensembl chr 8:40,153,482...40,155,310

G

tektin 2

increases expression

EXP

licochalcone B results in increased expression of TEKT2 mRNA

NCBI chr 1:36,084,094...36,088,275
Ensembl chr 1:36,084,094...36,088,278

G

terminal nucleotidyltransferase 5B

increases expression

EXP

licochalcone B results in increased expression of TENT5B mRNA

NCBI chr 1:27,005,020...27,012,850
Ensembl chr 1:27,005,020...27,012,850

G

terminal nucleotidyltransferase 5C

increases expression

EXP

licochalcone B results in increased expression of TENT5C mRNA

NCBI chr 1:117,606,048...117,628,389
Ensembl chr 1:117,606,048...117,628,389

G

transferrin

increases expression

EXP

licochalcone B results in increased expression of TF mRNA

NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641

G

transforming growth factor beta 2

decreases expression

EXP

licochalcone B results in decreased expression of TGFB2 mRNA

NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619

G

thrombospondin 1

increases expression

EXP

licochalcone B results in increased expression of THBS1 mRNA

NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,580,130...39,599,466

G

tigger transposable element derived 3

increases expression

EXP

licochalcone B results in increased expression of TIGD3 mRNA

NCBI chr11:65,354,751...65,357,613
Ensembl chr11:65,354,751...65,357,613

G

transmembrane protein 178B

decreases expression

EXP

licochalcone B results in decreased expression of TMEM178B mRNA

NCBI chr 7:141,074,064...141,511,296
Ensembl chr 7:141,074,064...141,480,380

G

transmembrane protein 191B

increases expression

EXP

licochalcone B results in increased expression of TMEM191B mRNA

NCBI chr22:18,527,802...18,530,573
Ensembl chr22:18,527,802...18,530,573

G

transmembrane protein 191C

increases expression

EXP

licochalcone B results in increased expression of TMEM191C mRNA

NCBI chr22:21,467,387...21,469,935
Ensembl chr22:21,466,423...21,471,269

G

transmembrane protein 61

decreases expression

EXP

licochalcone B results in decreased expression of TMEM61 mRNA

NCBI chr 1:54,980,628...54,992,288
Ensembl chr 1:54,886,833...54,992,296

G

transmembrane protein 92

decreases expression

EXP

licochalcone B results in decreased expression of TMEM92 mRNA

NCBI chr17:50,271,406...50,281,485
Ensembl chr17:50,271,406...50,281,485

G

thiol methyltransferase 1A

decreases expression

EXP

licochalcone B results in decreased expression of TMT1A mRNA

NCBI chr12:50,925,015...50,932,508
Ensembl chr12:50,923,472...50,932,510

G

tumor necrosis factor

multiple interactions

ISO

licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]

NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336

G

TNF receptor superfamily member 10a

increases expression

EXP

licochalcone B results in increased expression of TNFRSF10A protein

NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,121

G

TNF receptor superfamily member 10b

increases expression
multiple interactions

EXP

licochalcone B results in increased expression of TNFRSF10B protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [licochalcone B results in increased expression of TNFRSF10B protein]; pyrazolanthrone inhibits the reaction [licochalcone B results in increased expression of TNFRSF10B protein]; TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of CASP8 protein]; TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of PARP1 protein]

NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,071

G

TNF receptor superfamily member 10d

increases expression

EXP

licochalcone B results in increased expression of TNFRSF10D mRNA

NCBI chr 8:23,135,588...23,164,027
Ensembl chr 8:23,135,588...23,164,027

G

TNF receptor superfamily member 12A

increases expression

EXP

licochalcone B results in increased expression of TNFRSF12A mRNA

NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,385

G

TNF superfamily member 15

decreases expression

EXP

licochalcone B results in decreased expression of TNFSF15 mRNA

NCBI chr 9:114,784,635...114,806,039
Ensembl chr 9:114,784,652...114,806,039

G

TNF superfamily member 9

increases expression

EXP

licochalcone B results in increased expression of TNFSF9 mRNA

NCBI chr19:6,531,026...6,535,924
Ensembl chr19:6,531,026...6,535,924

G

tyrosine kinase non receptor 1

increases expression

EXP

licochalcone B results in increased expression of TNK1 mRNA

NCBI chr17:7,380,047...7,389,742
Ensembl chr17:7,380,534...7,389,774

G

troponin C2, fast skeletal type

increases expression

EXP

licochalcone B results in increased expression of TNNC2 mRNA

NCBI chr20:45,823,214...45,833,306
Ensembl chr20:45,823,214...45,833,745

G

tensin 1

decreases expression

EXP

licochalcone B results in decreased expression of TNS1 mRNA

NCBI chr 2:217,799,791...218,033,982
Ensembl chr 2:217,799,588...218,033,982

G

taperin

increases expression

EXP

licochalcone B results in increased expression of TPRN mRNA

NCBI chr 9:137,191,619...137,200,741
Ensembl chr 9:137,191,617...137,204,193

G

trafficking protein particle complex subunit 14

increases expression

EXP

licochalcone B results in increased expression of TRAPPC14 mRNA

NCBI chr 7:100,154,423...100,158,723
Ensembl chr 7:100,154,420...100,158,723

G

trafficking protein particle complex subunit 3L

decreases expression

EXP

licochalcone B results in decreased expression of TRAPPC3L mRNA

NCBI chr 6:116,494,989...116,545,684
Ensembl chr 6:116,494,989...116,545,684

G

tripartite motif containing 26

increases expression

EXP

licochalcone B results in increased expression of TRIM26 mRNA

NCBI chr 6:30,184,455...30,213,406
Ensembl chr 6:30,184,446...30,213,435

G

tripartite motif containing 36

increases expression

EXP

licochalcone B results in increased expression of TRIM36 mRNA

NCBI chr 5:115,124,772...115,180,294
Ensembl chr 5:115,124,762...115,180,546

G

tripartite motif containing 73

increases expression

EXP

licochalcone B results in increased expression of TRIM73 mRNA

NCBI chr 7:75,395,629...75,405,605
Ensembl chr 7:75,395,063...75,410,996

G

tripartite motif containing 74

increases expression

EXP

licochalcone B results in increased expression of TRIM74 mRNA

NCBI chr 7:72,954,868...72,969,681
Ensembl chr 7:72,959,485...72,969,466

G

TMF1 regulated nuclear protein 1

increases expression

EXP

licochalcone B results in increased expression of TRNP1 mRNA

NCBI chr 1:26,993,692...27,000,886
Ensembl chr 1:26,993,692...27,001,912

G

TSC22 domain family member 2

increases expression

EXP

licochalcone B results in increased expression of TSC22D2 mRNA

NCBI chr 3:150,408,298...150,466,422
Ensembl chr 3:150,408,298...150,466,422

G

tetraspanin 19

decreases expression

EXP

licochalcone B results in decreased expression of TSPAN19 mRNA

NCBI chr12:85,014,317...85,036,277
Ensembl chr12:85,014,311...85,036,277

G

tetraspanin 5

decreases expression

EXP

licochalcone B results in decreased expression of TSPAN5 mRNA

NCBI chr 4:98,470,367...98,658,611
Ensembl chr 4:98,470,365...98,658,690

G

TSPO associated protein 1

increases expression

EXP

licochalcone B results in increased expression of TSPOAP1 mRNA

NCBI chr17:58,301,231...58,328,795
Ensembl chr17:58,301,228...58,328,795

G

tetratricopeptide repeat domain 23 like

increases expression

EXP

licochalcone B results in increased expression of TTC23L mRNA

NCBI chr 5:34,839,164...34,925,682
Ensembl chr 5:34,838,833...34,900,511

G

tetratricopeptide repeat domain 39B

decreases expression

EXP

licochalcone B results in decreased expression of TTC39B mRNA

NCBI chr 9:15,163,622...15,307,216
Ensembl chr 9:15,163,622...15,307,360

G

tubulin beta 2A class IIa

increases expression

EXP

licochalcone B results in increased expression of TUBB2A mRNA

NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544

G

tubulin beta 3 class III

increases expression

EXP

licochalcone B results in increased expression of TUBB3 mRNA

NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761

G

tubulin beta 4B class IVb

increases expression

EXP

licochalcone B results in increased expression of TUBB4B mRNA

NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707

G

TUB like protein 2

increases expression

EXP

licochalcone B results in increased expression of TULP2 mRNA

NCBI chr19:48,880,967...48,898,744
Ensembl chr19:48,880,965...48,898,744

G

thioredoxin interacting protein

decreases expression

EXP

licochalcone B results in decreased expression of TXNIP mRNA

NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,580

G

tRNA-yW synthesizing protein 1 homolog B

increases expression

EXP

licochalcone B results in increased expression of TYW1B mRNA

NCBI chr 7:72,574,513...72,828,200
Ensembl chr 7:72,558,744...72,828,260

G

UDP-N-acetylglucosamine pyrophosphorylase 1

increases expression

EXP

licochalcone B results in increased expression of UAP1 mRNA

NCBI chr 1:162,561,531...162,601,240
Ensembl chr 1:162,561,481...162,601,259

G

ubiquitin like modifier activating enzyme 7

increases expression

EXP

licochalcone B results in increased expression of UBA7 mRNA

NCBI chr 3:49,805,209...49,813,953
Ensembl chr 3:49,805,205...49,814,151

G

UBA like domain containing 2

increases expression

EXP

licochalcone B results in increased expression of UBALD2 mRNA

NCBI chr17:76,265,348...76,271,298
Ensembl chr17:76,265,348...76,271,298

G

ubiquitin B

increases expression

EXP

licochalcone B results in increased expression of UBB mRNA

NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,667...16,382,745

G

ubiquitin C

increases expression

EXP

licochalcone B results in increased expression of UBC mRNA

NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368

G

ubiquitin conjugating enzyme E2 S

increases expression

EXP

licochalcone B results in increased expression of UBE2S mRNA

NCBI chr19:55,399,745...55,407,788
Ensembl chr19:55,399,745...55,407,788

G

ubiquitin C-terminal hydrolase L1

increases expression

EXP

licochalcone B results in increased expression of UCHL1 mRNA

NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,560

G

uncoupling protein 3

increases expression

EXP

licochalcone B results in increased expression of UCP3 mRNA

NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085

G

UDP-glucose ceramide glucosyltransferase

increases expression

EXP

licochalcone B results in increased expression of UGCG mRNA

NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,374

G

UL16 binding protein 1

increases expression

EXP

licochalcone B results in increased expression of ULBP1 mRNA

NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715

G

unc-80 homolog, NALCN channel complex subunit

increases expression

EXP

licochalcone B results in increased expression of UNC80 mRNA

NCBI chr 2:209,771,832...209,999,296
Ensembl chr 2:209,771,569...209,999,300

G

uridine phosphorylase 1

increases expression

EXP

licochalcone B results in increased expression of UPP1 mRNA

NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736

G

ubiquinol-cytochrome c reductase hinge protein like

increases expression

EXP

licochalcone B results in increased expression of UQCRHL mRNA

NCBI chr 1:15,807,374...15,807,649
Ensembl chr 1:15,807,169...15,809,348

G

vasorin

increases expression

EXP

licochalcone B results in increased expression of VASN mRNA

NCBI chr16:4,371,848...4,383,538
Ensembl chr16:4,371,848...4,383,538

G

vav guanine nucleotide exchange factor 1

increases expression

EXP

licochalcone B results in increased expression of VAV1 mRNA

NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,694...6,857,366

G

vascular endothelial growth factor D

increases expression

EXP

licochalcone B results in increased expression of VEGFD mRNA

NCBI chr X:15,345,596...15,384,413
Ensembl chr X:15,345,594...15,384,509

G

VGF nerve growth factor inducible

increases expression

EXP

licochalcone B results in increased expression of VGF mRNA

NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,167,227

G

vitelline membrane outer layer 1 homolog

increases expression

EXP

licochalcone B results in increased expression of VMO1 mRNA

NCBI chr17:4,785,285...4,786,364
Ensembl chr17:4,785,285...4,786,433

G

V-set pre-B cell surrogate light chain 3

increases expression

EXP

licochalcone B results in increased expression of VPREB3 mRNA

NCBI chr22:23,752,743...23,754,425
Ensembl chr22:23,752,743...23,754,425

G

von Willebrand factor A domain containing 3A

increases expression

EXP

licochalcone B results in increased expression of VWA3A mRNA

NCBI chr16:22,092,541...22,156,964
Ensembl chr16:22,092,528...22,156,964

G

von Willebrand factor A domain containing 5B2

increases expression

EXP

licochalcone B results in increased expression of VWA5B2 mRNA

NCBI chr 3:184,229,585...184,242,329
Ensembl chr 3:184,228,996...184,242,342

G

WD repeat domain 38

increases expression

EXP

licochalcone B results in increased expression of WDR38 mRNA

NCBI chr 9:124,853,460...124,857,878
Ensembl chr 9:124,853,266...124,859,132

G

WD repeat domain 47

increases expression

EXP

licochalcone B results in increased expression of WDR47 mRNA

NCBI chr 1:108,970,214...109,042,102
Ensembl chr 1:108,970,211...109,042,169

G

WD repeat domain 49

increases expression

EXP

licochalcone B results in increased expression of WDR49 mRNA

NCBI chr 3:167,478,684...167,657,923
Ensembl chr 3:167,477,789...167,653,983

G

Wnt family member 4

increases expression

EXP

licochalcone B results in increased expression of WNT4 mRNA

NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969

G

Wnt family member 9A

increases expression

EXP

licochalcone B results in increased expression of WNT9A mRNA

NCBI chr 1:227,918,656...227,947,932
Ensembl chr 1:227,918,656...227,947,932

G

WT1 interacting protein

increases expression

EXP

licochalcone B results in increased expression of WTIP mRNA

NCBI chr19:34,481,758...34,512,304
Ensembl chr19:34,481,682...34,512,304

G

zinc activated ion channel

increases expression

EXP

licochalcone B results in increased expression of ZACN mRNA

NCBI chr17:76,079,182...76,082,806
Ensembl chr17:76,071,961...76,083,666

G

zinc finger CCCH-type containing 12A

increases expression

EXP

licochalcone B results in increased expression of ZC3H12A mRNA

NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,496...37,484,379

G

zinc finger AN1-type containing 2A

increases expression

EXP

licochalcone B results in increased expression of ZFAND2A mRNA

NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,151,903...1,160,771

G

ZFP36 ring finger protein

increases expression

EXP

licochalcone B results in increased expression of ZFP36 mRNA

NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407

G

zinc finger matrin-type 5

increases expression

EXP

licochalcone B results in increased expression of ZMAT5 mRNA

NCBI chr22:29,730,956...29,767,007
Ensembl chr22:29,728,138...29,767,084

G

zinc finger MYM-type containing 3

decreases expression

EXP

licochalcone B results in decreased expression of ZMYM3 mRNA

NCBI chr X:71,239,624...71,255,290
Ensembl chr X:71,239,617...71,255,269

G

zinc finger MYND-type containing 15

increases expression

EXP

licochalcone B results in increased expression of ZMYND15 mRNA

NCBI chr17:4,739,833...4,746,119
Ensembl chr17:4,739,108...4,746,119

G

zinc finger protein 296

increases expression

EXP

licochalcone B results in increased expression of ZNF296 mRNA

NCBI chr19:45,071,500...45,076,478
Ensembl chr19:45,071,500...45,076,478

G

zinc finger protein 382

increases expression

EXP

licochalcone B results in increased expression of ZNF382 mRNA

NCBI chr19:36,605,313...36,634,114
Ensembl chr19:36,604,817...36,634,114

G

zinc finger protein 439

increases expression

EXP

licochalcone B results in increased expression of ZNF439 mRNA

NCBI chr19:11,848,726...11,869,486
Ensembl chr19:11,848,726...11,883,750

G

zinc finger protein 473

increases expression

EXP

licochalcone B results in increased expression of ZNF473 mRNA

NCBI chr19:50,026,005...50,048,776
Ensembl chr19:50,025,714...50,053,414

G

zinc finger protein 490

increases expression

EXP

licochalcone B results in increased expression of ZNF490 mRNA

NCBI chr19:12,576,100...12,610,813
Ensembl chr19:12,576,100...12,640,098

G

zinc finger protein 518A

decreases expression

EXP

licochalcone B results in decreased expression of ZNF518A mRNA

NCBI chr10:96,129,715...96,205,291
Ensembl chr10:96,129,695...96,205,288

G

zinc finger protein 547

increases expression

EXP

licochalcone B results in increased expression of ZNF547 mRNA

NCBI chr19:57,363,551...57,379,565
Ensembl chr19:57,363,477...57,379,565

G

zinc finger protein 57

increases expression

EXP

licochalcone B results in increased expression of ZNF57 mRNA

NCBI chr19:2,900,928...2,918,473
Ensembl chr19:2,900,914...2,919,102

G

zinc finger protein 622

increases expression

EXP

licochalcone B results in increased expression of ZNF622 mRNA

NCBI chr 5:16,451,519...16,465,800
Ensembl chr 5:16,451,518...16,465,811

G

zinc finger protein 628

increases expression

EXP

licochalcone B results in increased expression of ZNF628 mRNA

NCBI chr19:55,476,617...55,484,487
Ensembl chr19:55,476,617...55,484,487

G

zinc finger protein 703

increases expression

EXP

licochalcone B results in increased expression of ZNF703 mRNA

NCBI chr 8:37,695,782...37,700,019
Ensembl chr 8:37,695,782...37,700,019

G

zinc finger protein 792

decreases expression

EXP

licochalcone B results in decreased expression of ZNF792 mRNA

NCBI chr19:34,956,354...34,964,229
Ensembl chr19:34,956,354...34,964,284

G

ZNF8-ERVK3-1 readthrough (NMD candidate)

increases expression

EXP

licochalcone B results in increased expression of ZNF8-ERVK3-1 mRNA

NCBI chr19:58,278,966...58,315,657
Ensembl chr19:58,278,966...58,315,197

G

zinc finger protein 827

decreases expression

EXP

licochalcone B results in decreased expression of ZNF827 mRNA

NCBI chr 4:145,757,627...145,938,823
Ensembl chr 4:145,757,627...145,938,823

G

zinc finger protein 831

decreases expression

EXP

licochalcone B results in decreased expression of ZNF831 mRNA

NCBI chr20:59,123,388...59,259,113
Ensembl chr20:59,123,381...59,259,113

G

zinc finger protein 853

increases expression

EXP

licochalcone B results in increased expression of ZNF853 mRNA

NCBI chr 7:6,615,610...6,624,290
Ensembl chr 7:6,615,348...6,624,290

G

zinc finger protein 860

decreases expression

EXP

licochalcone B results in decreased expression of ZNF860 mRNA

NCBI chr 3:31,981,750...32,006,443
Ensembl chr 3:31,981,722...31,991,723

G

zinc finger protein 92

increases expression

EXP

licochalcone B results in increased expression of ZNF92 mRNA

NCBI chr 7:65,373,855...65,401,136
Ensembl chr 7:65,373,799...65,401,136

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	26866
chemical entity	26846
atom	26842
nonmetal atom	26129
oxygen atom	25332
oxygen molecular entity	25332
flavonoids	12722
chalcones	1052
Licochalcone B	853
Path 2
Term	Annotations
CHEBI ontology	26866
subatomic particle	26844
composite particle	26844
hadron	26842
baryon	26844
nucleon	26842
atomic nucleus	26844
atom	26842
main group element atom	26592
p-block element atom	26592
carbon group element atom	26073
carbon atom	26011
organic molecular entity	26011
heteroorganic entity	25339
organochalcogen compound	24942
organooxygen compound	24567
carbonyl compound	23278
ketone	19635
alpha,beta-unsaturated ketone	10597
enone	10595
chalcones	1052
Licochalcone B	853

paths to the root