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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lipoamide
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Accession:CHEBI:17460 term browser browse the term
Definition:A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of lipoic acid with ammonia.
Synonyms:related_synonym: 1,2-dithiolane-3-pentanamide;   5-(1,2-dithiolan-3-yl)pentanamide;   Formula=C8H15NOS2;   InChI=1S/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10);   InChIKey=FCCDDURTIIUXBY-UHFFFAOYSA-N;   SMILES=NC(=O)CCCCC1CCSS1;   Thioctamide;   Thioctic acid amide;   alpha-lipoic acid amide;   lipoacin;   vitamin N
 alt_id: CHEBI:14518;   CHEBI:25055;   CHEBI:6491
 xref: Beilstein:122470;   CAS:940-69-2;   Gmelin:1126642;   HMDB:HMDB0000962;   KEGG:C00248;   KEGG:D00048;   LIPID_MAPS_instance:LMFA08010006
 xref_mesh: MESH:C013091
 xref: MetaCyc:LIPOAMIDE;   PMID:10224250;   PMID:21108628;   PMID:21521794;   Reaxys:122470;   Wikipedia:Lipoamide



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lipoamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO lipoamide inhibits the reaction [Acrolein results in decreased expression of NFE2L2 protein] CTD PMID:18258206 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases reduction ISO TXNRD1 protein results in increased reduction of lipoamide CTD PMID:21172426 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases reduction ISO TXNRD2 protein results in increased reduction of lipoamide CTD PMID:21172426 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        antimicrobial agent 18274
          antibacterial agent 16377
            octanoic acid 4919
              lipoic acid 217
                lipoamide 3
                  (R)-lipoamide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            heteroorganic entity 19549
                              organochalcogen compound 19309
                                organooxygen compound 19204
                                  carbon oxoacid 18689
                                    carboxylic acid 18686
                                      monocarboxylic acid 18026
                                        fatty acid 16849
                                          saturated fatty acid 16569
                                            straight-chain saturated fatty acid 16103
                                              octanoic acid 4919
                                                lipoic acid 217
                                                  lipoamide 3
                                                    (R)-lipoamide 0
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