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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-nitrophenyl phosphate
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Accession:CHEBI:17440 term browser browse the term
Definition:An aryl phosphate resulting from the mono-esterification of phosphoric acid with 4-nitrophenol.
Synonyms:related_synonym: 4-nitrophenyl dihydrogen phosphate;   Formula=C6H6NO6P;   InChI=1S/C6H6NO6P/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12/h1-4H,(H2,10,11,12);   InChIKey=XZKIHKMTEMTJQX-UHFFFAOYSA-N;   SMILES=OP(O)(=O)Oc1ccc(cc1)[N+]([O-])=O;   nitrophenylphosphate;   p-nitrophenyl dihydrogen phosphate;   p-nitrophenyl phosphate;   phosphoric acid, mono(4-nitrophenyl) ester;   phosphoric acid, mono(p-nitrophenyl) ester
 alt_id: CHEBI:12035;   CHEBI:1915;   CHEBI:20458;   CHEBI:40049
 xref: CAS:330-13-2;   DrugBank:DB04214;   HMDB:HMDB0060272;   KEGG:C03360
 xref_mesh: MESH:C008644
 xref: MetaCyc:CPD-194;   PDBeChem:4NP;   PMID:23305417;   Reaxys:1578142;   Wikipedia:Para-Nitrophenylphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:61146


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4-nitrophenyl phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp1 acid phosphatase 1 multiple interactions
increases hydrolysis		 ISO Benzoic Acid analog inhibits the reaction [ACP1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [ACP1 protein results in increased hydrolysis of nitrophenylphosphate] CTD PMID:24287560 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021 		JBrowse link
G Alpp alkaline phosphatase, placental increases chemical synthesis ISO ALPP protein results in increased chemical synthesis of nitrophenylphosphate CTD PMID:1495895 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606 		JBrowse link
G Dusp23 dual specificity phosphatase 23 decreases phosphorylation
multiple interactions		 ISO DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate
Edetic Acid inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]; Ethylmaleimide inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]; Vanadates inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]		 CTD PMID:15147733 NCBI chr13:85,097,899...85,100,054
Ensembl chr13:85,097,899...85,100,093 		JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of nitrophenylphosphate analog CTD PMID:24338473 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions
increases hydrolysis		 ISO Benzoic Acid analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate] CTD PMID:24287560 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 increases hydrolysis
multiple interactions		 ISO PTPN2 protein results in increased hydrolysis of nitrophenylphosphate
Benzoic Acid analog inhibits the reaction [PTPN2 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN2 protein results in increased hydrolysis of nitrophenylphosphate]		 CTD PMID:24287560 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          metabolite 19562
            xenobiotic metabolite 16176
              human xenobiotic metabolite 15795
                4-nitrophenol 1318
                  4-nitrophenyl phosphate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      chalcogen 19598
                        oxygen atom 19570
                          oxygen molecular entity 19570
                            hydroxides 19374
                              oxoacid 18808
                                pnictogen oxoacid 14987
                                  phosphorus oxoacid 14587
                                    phosphoric acids 13935
                                      phosphoric acid 13935
                                        phosphoric acid derivative 13817
                                          phosphate 13843
                                            organic phosphate 13816
                                              aryl phosphate 7620
                                                4-nitrophenyl phosphate 6
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