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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-nitrophenyl phosphate
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Accession:CHEBI:17440 term browser browse the term
Definition:An aryl phosphate resulting from the mono-esterification of phosphoric acid with 4-nitrophenol.
Synonyms:related_synonym: 4-nitrophenyl dihydrogen phosphate;   nitrophenylphosphate;   p-nitrophenyl dihydrogen phosphate;   p-nitrophenyl phosphate;   phosphoric acid, mono(4-nitrophenyl) ester;   phosphoric acid, mono(p-nitrophenyl) ester
 alt_id: CHEBI:12035;   CHEBI:1915;   CHEBI:20458;   CHEBI:40049
 xref: CAS:330-13-2;   DrugBank:DB04214;   HMDB:HMDB0060272
 xref_mesh: MESH:C008644
 xref: Reaxys:1578142;   kegg.compound:C03360;   metacyc.compound:CPD-194;   pdb-ccd:4NP;   pubmed:23305417;   wikipedia.en:Para-Nitrophenylphosphate
 chemrof_formula: C6H6NO6P
 chemrof_inchi: InChI=1S/C6H6NO6P/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12/h1-4H,(H2,10,11,12)
 chemrof_smiles: O=[N+]([O-])c1ccc(OP(=O)(O)O)cc1
 chemrof_inchikey: XZKIHKMTEMTJQX-UHFFFAOYSA-N
 cyclic_relationship: has_functional_parent CHEBI:16836;   is_conjugate_acid_of CHEBI:61146


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4-nitrophenyl phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp1 acid phosphatase 1 multiple interactions
increases hydrolysis 		ISO Benzoic Acid analog inhibits the reaction [ACP1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [ACP1 protein results in increased hydrolysis of nitrophenylphosphate] CTD PMID:24287560 NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959 		JBrowse link
G Alpp alkaline phosphatase, placental increases chemical synthesis ISO ALPP protein results in increased chemical synthesis of nitrophenylphosphate CTD PMID:1495895 NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451 		JBrowse link
G Dusp23 dual specificity phosphatase 23 decreases phosphorylation
multiple interactions 		ISO DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate
Edetic Acid inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]; Ethylmaleimide inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]; Vanadates inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate] 		CTD PMID:15147733 NCBI chr13:87,630,245...87,632,400
Ensembl chr13:87,630,245...87,632,400 		JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of nitrophenylphosphate analog CTD PMID:24338473 NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions
increases hydrolysis 		ISO Benzoic Acid analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate] CTD PMID:24287560 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 increases hydrolysis
multiple interactions 		ISO PTPN2 protein results in increased hydrolysis of nitrophenylphosphate
Benzoic Acid analog inhibits the reaction [PTPN2 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN2 protein results in increased hydrolysis of nitrophenylphosphate] 		CTD PMID:24287560 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        biochemical role 19888
          metabolite 19624
            eukaryotic metabolite 19368
              animal metabolite 19180
                mammalian metabolite 19186
                  mouse metabolite 18375
                    4-nitrophenyl phosphate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      pnictogen 19695
                        phosphorus atom 14760
                          phosphorus molecular entity 14760
                            phosphorus oxoacids and derivatives 14745
                              phosphorus oxoacid derivative 14118
                                phosphoric acid derivative 13866
                                  phosphate 13865
                                    organic phosphate 13865
                                      aryl phosphate 7643
                                        4-nitrophenyl phosphate 6
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