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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-pyridoxic acid
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Accession:CHEBI:17405 term browser browse the term
Definition:A methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine.
Synonyms:related_synonym: 2-methyl-3-hydroxy-4-carboxy-5-hydroxymethylpyridine;   3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxylic acid;   3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinic acid;   3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxylic acid;   4-Pyridoxinsaeure;   4-pyridoxinecarboxylic acid;   4-pyridoxinic acid;   4-pyridoxylic acid;   pyridoxic acid
 alt_id: CHEBI:1928;   CHEBI:20474
 xref: CAS:82-82-6;   Chemspider:6467;   HMDB:HMDB0000017;   KNApSAcK:C00052160
 xref_mesh: MESH:D011735
 xref: Reaxys:384006;   foodb.food:FDB021874;   kegg.compound:C00847;   metacyc.compound:CPD-1112;   pubmed:11756060;   pubmed:1462525;   pubmed:14747687;   pubmed:1783639;   pubmed:17868768;   pubmed:22770225;   pubmed:23535534;   pubmed:2580028;   pubmed:28778380;   pubmed:30845778;   pubmed:32346589;   pubmed:8505768
 chemrof_formula: C8H9NO4
 chemrof_smiles: Cc1ncc(CO)c(C(=O)O)c1O
 chemrof_inchikey: HXACOUQIXZGNBF-UHFFFAOYSA-N
 chemrof_inchi: InChI=1S/C8H9NO4/c1-4-7(11)6(8(12)13)5(3-10)2-9-4/h2,10-11H,3H2,1H3,(H,12,13)
 cyclic_relationship: has_functional_parent CHEBI:6032;   is_conjugate_acid_of CHEBI:30959


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4-pyridoxic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pyridoxic Acid CTD PMID:24709313 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        biochemical role 19888
          vitamin (role) 13606
            water-soluble vitamin (role) 9750
              B vitamin 9530
                vitamin B6 27
                  4-pyridoxic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                organic heterocyclic compound 19381
                                  organic heteromonocyclic compound 18004
                                    pyridines 12197
                                      hydroxypyridine 89
                                        monohydroxypyridine 58
                                          4-pyridoxic acid 1
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