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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:D-glyceraldehyde
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Accession:CHEBI:17378 term browser browse the term
Definition:The D-enantiomer of glyceraldehyde.
Synonyms:exact_synonym: (2R)-2,3-dihydroxypropanal
 related_synonym: D-2,3-dihydroxypropanal;   D-2,3-dihydroxypropionaldehyde;   D-aldotriose;   D-glycerose;   Formula=C3H6O3;   GLYCERALDEHYDE;   InChI=1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2/t3-/m0/s1;   InChIKey=MNQZXJOMYWMBOU-VKHMYHEASA-N;   SMILES=[H]C(=O)[C@H](O)CO
 alt_id: CHEBI:12982;   CHEBI:21025;   CHEBI:39973;   CHEBI:4186
 xref: Beilstein:1720474;   Beilstein:5726453;   CAS:367-47-5;   CAS:453-17-8;   ECMDB:ECMDB01051;   KEGG:C00577
 xref_mesh: MESH:D005985
 xref: PDBeChem:3GR;   Reaxys:1720474;   YMDB:YMDB00575
 cyclic_relationship: is_enantiomer_of CHEBI:27975


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D-glyceraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 decreases activity ISO Glyceraldehyde results in decreased activity of AKR1A1 protein CTD PMID:30469331 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction
decreases activity		 ISO AKR1B1 protein results in increased reduction of Glyceraldehyde
Glyceraldehyde results in decreased activity of AKR1B1 protein		 CTD PMID:19014918 PMID:30469331 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
increases metabolic processing
increases reduction
decreases activity		 ISO [AKR1B10 protein co-treated with NADP] affects the reduction of Glyceraldehyde; ciprofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; pirinixic acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; sorbinil inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; zopolrestat inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
AKR1B10 protein results in increased metabolism of Glyceraldehyde
Glyceraldehyde results in decreased activity of AKR1B10 protein		 CTD PMID:17329238 PMID:18325492 PMID:19014918 PMID:19028477 PMID:30469331 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases metabolic processing ISO AKR1B15 protein results in increased metabolism of Glyceraldehyde CTD PMID:21276782 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde CTD PMID:21376711 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of Glyceraldehyde CTD PMID:25451588 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Ins1 insulin 1 increases secretion EXP Glyceraldehyde results in increased secretion of INS1 protein CTD PMID:11377826 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP PLCB1 protein promotes the reaction [Glyceraldehyde results in increased abundance of Inositol Phosphates] CTD PMID:11377826 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        biochemical role 19596
          metabolite 19558
            fundamental metabolite 14541
              glyceraldehyde 12
                D-glyceraldehyde 8
                  D-glyceraldehyde 3-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            heteroorganic entity 19556
                              organochalcogen compound 19315
                                organooxygen compound 19205
                                  carbohydrates and carbohydrate derivatives 15294
                                    carbohydrate 15294
                                      monosaccharide 4816
                                        aldose 3228
                                          aldotriose 12
                                            glyceraldehyde 12
                                              D-glyceraldehyde 8
                                                D-glyceraldehyde 3-phosphate 0
paths to the root