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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:all-trans-retinol
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Accession:CHEBI:17336 term browser browse the term
Definition:A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Synonyms:related_synonym: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol;   (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol;   Alphalin;   Aquasol A;   Chocola A;   Formula=C20H30O;   InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+;   InChIKey=FPIPGXGPPPQFEQ-OVSJKPMPSA-N;   Retinol;   SMILES=C\\C(=C/CO)\\C=C\\C=C(/C)\\C=C\\C1=C(C)CCCC1(C)C;   Vitamin A;   Vitamin A1;   all-trans-retinyl alcohol;   all-trans-vitamin A;   all-trans-vitamin A alcohol;   retinol (vit A);   retinolum;   trans-retinol;   vitamin A alcohol;   vitamin A1 alcohol
 alt_id: CHEBI:12783;   CHEBI:22349;   CHEBI:8816
 xref: Beilstein:403040;   CAS:11103-57-4;   CAS:68-26-8;   Chemspider:393012;   DrugBank:DB00162;   Drug_Central:2831;   Gmelin:247497;   HMDB:HMDB0000305;   KEGG:C00473;   KEGG:C17276;   KEGG:D00069;   KEGG:D06543;   KNApSAcK:C00031437;   LIPID_MAPS_instance:LMPR01090001
 xref_mesh: MESH:D014801
 xref: MetaCyc:CPD-13524;   PDBeChem:RTL;   PMID:10637381;   PMID:12074187;   PMID:12221269;   PMID:12229281;   PMID:12548314;   PMID:12600856;   PMID:1414975;   PMID:15041701;   PMID:15051608;   PMID:15531678;   PMID:15622799;   PMID:15929633;   PMID:16469975;   PMID:16507353;   PMID:16825693;   PMID:17790232;   PMID:19264891;   PMID:20697621;   PMID:2217163;   PMID:22444309;   PMID:2295828;   PMID:25478840;   PMID:30510477;   PMID:31484771;   PMID:7971717;   PMID:8464067;   PMID:8496140;   PMID:9155646;   PMID:9736606;   Wikipedia:Retinol


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all-trans-retinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression		 EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA]
Vitamin A results in decreased expression of ABCB1 mRNA; Vitamin A results in decreased expression of ABCB1A mRNA		 CTD PMID:15327746 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression ISO Vitamin A results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP Vitamin A deficiency results in decreased expression of ACSS2 mRNA CTD PMID:12163651 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Vitamin A inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:16256175 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actb actin, beta decreases expression EXP Vitamin A deficiency results in decreased expression of ACTB mRNA CTD PMID:12163651 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression
multiple interactions		 EXP Vitamin A results in decreased expression of ACTG2 protein
Vitamin A results in decreased expression of [Ethanol results in increased expression of ACTG2 protein]		 CTD PMID:16043492 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Afp alpha-fetoprotein increases expression EXP Vitamin A deficiency results in increased expression of AFP mRNA CTD PMID:7519440 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased expression of AGER protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased expression of AGER protein]; [Vitamin A results in increased abundance of Reactive Oxygen Species] which results in increased expression of AGER protein; SB 203580 inhibits the reaction [Vitamin A results in increased expression of AGER protein] CTD PMID:18396385 PMID:21807062 PMID:22274401 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA] CTD PMID:15728703 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases response to substance ISO AKR1B1 protein results in decreased susceptibility to Vitamin A; AKR1B1 protein results in decreased susceptibility to Vitamin A metabolite CTD PMID:19014918 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases response to substance ISO AKR1B10 protein results in decreased susceptibility to Vitamin A; AKR1B10 protein results in decreased susceptibility to Vitamin A metabolite CTD PMID:19014918 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein] CTD PMID:21807062 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin affects binding ISO Vitamin A binds to ALB protein CTD PMID:17184834 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Vitamin A results in decreased expression of ALDH1A2 mRNA CTD PMID:30944279 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Vitamin A] results in increased activity of AOX1 protein; [Tetrachlorodibenzodioxin co-treated with Vitamin A] results in increased expression of AOX1 mRNA; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AOX1 protein]; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AOX1 mRNA] CTD PMID:16292751 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Apod apolipoprotein D affects binding ISO Vitamin A binds to APOD protein CTD PMID:16461020 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
affects expression		 EXP Tretinoin inhibits the reaction [Vitamin A affects the expression of APP mRNA]
Vitamin A results in increased expression of APP protein		 CTD PMID:16530976 PMID:22274401 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression EXP Vitamin A deficiency results in increased expression of ASCL1 mRNA CTD PMID:12555267 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions
affects expression		 EXP Tretinoin inhibits the reaction [Vitamin A affects the expression of BACE mRNA] CTD PMID:16530976 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Vitamin A results in increased expression of BAX protein CTD PMID:16216918 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Vitamin A results in decreased expression of BCL2 protein CTD PMID:16216918 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression ISO Vitamin A affects the expression of BMP4 mRNA CTD PMID:16120438 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Vitamin A results in increased expression of BTG2 mRNA CTD PMID:17234770 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Cab39 calcium binding protein 39 decreases expression EXP Vitamin A deficiency results in decreased expression of CAB39 mRNA CTD PMID:12163651 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
increases activity		 ISO alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]
Vitamin A results in decreased activity of CASP3 protein		 CTD PMID:16531423 PMID:17618090 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase affects activity
decreases activity
increases expression
multiple interactions
decreases expression		 ISO
EXP		 Vitamin A affects the activity of CAT protein
Vitamin A results in decreased activity of CAT protein
Vitamin A results in increased expression of CAT protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased expression of CAT protein]; [Vitamin A results in decreased activity of CAT protein] which results in increased abundance of Hydrogen Peroxide; Vitamin A results in increased expression of and results in increased activity of CAT protein
Vitamin A deficiency results in decreased expression of CAT protein; Vitamin A results in decreased expression of CAT protein		 CTD PMID:8602878 PMID:16036340 PMID:17673185 PMID:17727954 PMID:18440196 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases expression
affects expression		 ISO
EXP		 Vitamin A results in decreased expression of CCL2 protein
Vitamin A results in increased expression of CCL2 mRNA
Vitamin A affects the expression of CCL2 protein		 CTD PMID:16988133 PMID:25051504 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Vitamin A results in decreased expression of CCND1 mRNA CTD PMID:17219422 PMID:17234770 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression EXP Vitamin A deficiency results in decreased expression of CCND2 mRNA CTD PMID:12163651 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Vitamin A results in increased expression of CD14 mRNA CTD PMID:17033190 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd44 CD44 molecule increases expression ISO Vitamin A results in increased expression of CD44 protein CTD PMID:16724877 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdh1 cadherin 1 affects expression ISO Vitamin A affects the expression of CDH1 mRNA CTD PMID:17034753 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions		 ISO Vitamin A results in increased expression of COL1A1 mRNA
[Cryptoxanthins co-treated with Vitamin A] results in increased expression of COL1A1 mRNA		 CTD PMID:15962303 PMID:17034753 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA] CTD PMID:16397886 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO Vitamin A results in increased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions
increases expression		 ISO CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA]
Vitamin A results in increased expression of CRABP2 mRNA		 CTD PMID:16793012 PMID:17034753 PMID:17234770 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions		 ISO
EXP		 Vitamin A results in increased phosphorylation of CREB1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]		 CTD PMID:16280361 PMID:16510265 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression		 ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; MG 262 inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; Vitamin A results in increased ubiquitination of and results in increased degradation of CTNNB1 protein CTD PMID:17219422 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Vitamin A affects the localization of CYCS protein CTD PMID:16202537 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:15728703 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases oxidation
decreases activity		 ISO CYP1B1 protein results in increased oxidation of Vitamin A
Vitamin A results in decreased activity of CYP1B1 protein		 CTD PMID:15258110 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions
increases expression
affects metabolic processing		 ISO
EXP		 [Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA
Vitamin A results in increased expression of CYP26A1 mRNA
[R 115866 co-treated with Vitamin A] results in increased expression of CYP26A1 mRNA
CYP26A1 protein affects the metabolism of Vitamin A		 CTD PMID:10557354 PMID:16194896 PMID:17244623 PMID:17510468 PMID:22542753 More... NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [R 115866 co-treated with Vitamin A] results in increased expression of CYP26B1 mRNA CTD PMID:17510468 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein]; Vitamin A affects the expression of and affects the activity of CYP2C11 protein CTD PMID:15963505 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Dcp2 decapping mRNA 2 decreases expression EXP Vitamin A deficiency results in decreased expression of DCP2 mRNA CTD PMID:12163651 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] CTD PMID:16214399 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dhh desert hedgehog signaling molecule multiple interactions EXP Vitamin A inhibits the reaction [Valproic Acid results in increased expression of DHH mRNA] CTD PMID:35594946 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases abundance ISO DHRS3 gene mutant form results in decreased abundance of Vitamin A CTD PMID:24005908 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases metabolic processing ISO DHRS9 protein results in increased metabolism of Vitamin A CTD PMID:11304534 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP Vitamin A results in decreased expression of DRD2 protein CTD PMID:22274401 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Vitamin A deficiency results in decreased expression of EEF1A1 mRNA CTD PMID:12163651 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP Vitamin A deficiency results in increased expression of EGFR mRNA CTD PMID:7519440 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Vitamin A deficiency results in decreased expression of EIF4A2 mRNA CTD PMID:12163651 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Epo erythropoietin increases expression
multiple interactions		 ISO
EXP		 Vitamin A results in increased expression of EPO protein
Vitamin A inhibits the reaction [Hydrogen Peroxide results in decreased expression of EPO protein]		 CTD PMID:9927288 PMID:16960172 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Vitamin A inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:19340624 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Vitamin A results in decreased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fn1 fibronectin 1 decreases secretion ISO Vitamin A results in decreased secretion of FN1 protein CTD PMID:17225872 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha multiple interactions EXP [Vitamin A co-treated with perillyl alcohol] results in decreased expression of FNTA protein CTD PMID:15959631 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460 		JBrowse link
G Fntb farnesyltransferase, CAAX box, subunit beta multiple interactions
increases expression		 EXP [perillyl alcohol co-treated with Vitamin A] results in decreased expression of FNTB mRNA
Vitamin A results in increased expression of FNTB mRNA; Vitamin A results in increased expression of FNTB protein		 CTD PMID:15959631 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586 		JBrowse link
G Foxa1 forkhead box A1 increases expression ISO Vitamin A results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP Vitamin A inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein] CTD PMID:16863852 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
decreases expression		 EXP Iron deficiency promotes the reaction [Vitamin A deficiency results in decreased expression of FTH1 protein]
Vitamin A deficiency results in decreased expression of FTH1 mRNA; Vitamin A deficiency results in decreased expression of FTH1 protein		 CTD PMID:22154532 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression ISO Vitamin A results in increased expression of GABRB3 mRNA CTD PMID:17225872 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO Vitamin A results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gcg glucagon multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of GCG mRNA CTD PMID:17244017 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein] CTD PMID:15963505 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression		 EXP Vitamin A inhibits the reaction [nitrofen results in increased expression of GJA1 mRNA]
Vitamin A results in increased expression of GJA1 mRNA		 CTD PMID:12031251 PMID:16292552 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gnai1 G protein subunit alpha i1 increases expression EXP Vitamin A results in increased expression of GNAI1 protein CTD PMID:16757122 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression EXP Vitamin A results in increased expression of GNAI2 protein CTD PMID:16757122 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions		 EXP Vitamin A results in increased activity of GPT protein
gadolinium chloride inhibits the reaction [Vitamin A results in increased activity of GPT protein]		 CTD PMID:8627517 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein CTD PMID:17179735 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 increases response to substance ISO GRHL3 gene mutant form results in increased susceptibility to Vitamin A CTD PMID:6635991 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Vitamin A inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G H3f4 H3.4 histone, cluster member multiple interactions
increases acetylation		 ISO Vitamin A affects the reaction [H3F4 protein modified form binds to PCK1 promoter]
Vitamin A results in increased acetylation of H3F4 protein		 CTD PMID:16317119 NCBI chr10:43,740,702...43,741,262 JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Vitamin A results in increased expression of HBEGF mRNA CTD PMID:19648781 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hoxa1 homeobox A1 multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased expression of HOXA1]; 3,4-methylenedioxy-beta-nitrostyrene inhibits the reaction [Vitamin A results in increased expression of HOXA1]; 4-nonylphenol inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; BAY 11-7085 inhibits the reaction [Vitamin A results in increased expression of HOXA1]; bisphenol A inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Camptothecin inhibits the reaction [Vitamin A results in increased expression of HOXA1]; citral inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; di-n-pentyl phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Dibutyl Phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Diethylstilbestrol inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Genistein inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; nitrofen inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]
Vitamin A results in increased expression of HOXA1; Vitamin A results in increased expression of HOXA1 mRNA		 CTD PMID:23696197 PMID:26820057 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Hoxa3 homeobox A3 affects expression ISO Vitamin A affects the expression of HOXA3 mRNA CTD PMID:10992263 NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218 		JBrowse link
G Ifng interferon gamma decreases expression
affects expression		 ISO
EXP		 Vitamin A results in decreased expression of IFNG protein
Vitamin A affects the expression of IFNG protein		 CTD PMID:14624943 PMID:17289162 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta increases expression EXP Vitamin A results in increased expression of IL1B protein CTD PMID:25051504 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 increases expression ISO Vitamin A results in increased expression of IL2 mRNA CTD PMID:15506942 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 decreases expression ISO Vitamin A results in decreased expression of IL4 protein CTD PMID:14624943 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Inhba inhibin subunit beta A multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in decreased expression of SHH mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of GCG mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of INS1 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of INS2 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PDX1 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PPY mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PTF1A mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of SST mRNA CTD PMID:17244017 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of INS1 mRNA CTD PMID:17244017 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of INS2 mRNA CTD PMID:17244017 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression EXP Vitamin A deficiency results in increased expression of IREB2 mRNA CTD PMID:22154532 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO Vitamin A results in increased expression of ITGA3 protein CTD PMID:17241391 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Itgb1 integrin subunit beta 1 affects localization
increases expression		 ISO Vitamin A affects the localization of ITGB1 protein
Vitamin A results in increased expression of ITGB1 protein		 CTD PMID:17241391 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Ivl involucrin increases expression ISO Vitamin A results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Jak2 Janus kinase 2 affects localization EXP Vitamin A affects the localization of JAK2 protein CTD PMID:15963505 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Krt18 keratin 18 increases expression ISO Vitamin A results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt19 keratin 19 increases expression
decreases expression		 ISO
EXP		 Vitamin A results in increased expression of KRT19 mRNA
Vitamin A deficiency results in decreased expression of KRT19 mRNA		 CTD PMID:12163651 PMID:17034753 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt7 keratin 7 increases expression ISO Vitamin A results in increased expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Krt8 keratin 8 increases expression ISO Vitamin A results in increased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Lep leptin multiple interactions EXP LEP gene mutant form promotes the reaction [Vitamin A results in increased expression of UCP1 mRNA] CTD PMID:16493122 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lrat lecithin retinol acyltransferase multiple interactions
decreases expression
affects expression
increases expression		 ISO
EXP		 [STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin A
Vitamin A results in decreased expression of LRAT mRNA
Vitamin A affects the expression of LRAT mRNA
Vitamin A results in increased expression of LRAT mRNA
[Vitamin A co-treated with Tetrachlorodibenzodioxin] results in increased expression of LRAT mRNA; Tetrachlorodibenzodioxin inhibits the reaction [Vitamin A results in increased expression of LRAT mRNA]		 CTD PMID:12576510 PMID:16292751 PMID:18316031 PMID:30944279 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Lrp2 LDL receptor related protein 2 multiple interactions ISO LRP2 protein results in increased uptake of and affects the abundance of Vitamin A CTD PMID:16251603 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
increases phosphorylation		 EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] CTD PMID:16510265 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
increases phosphorylation		 EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; Vitamin A results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:16043492 PMID:16510265 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; Vitamin A results in decreased phosphorylation of and results in decreased activity of MAPK3 protein CTD PMID:16043492 PMID:16510265 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mbl2 mannose binding lectin 2 multiple interactions ISO MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] CTD PMID:16960176 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO Vitamin A affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Meis1 Meis homeobox 1 increases expression
multiple interactions		 ISO Vitamin A results in increased expression of MEIS1 mRNA
[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]		 CTD PMID:16397886 PMID:17034753 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Meis2 Meis homeobox 2 increases expression
multiple interactions		 ISO Vitamin A results in increased expression of MEIS2 mRNA
[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA]		 CTD PMID:16397886 PMID:17034753 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696 		JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO Vitamin A results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression EXP Vitamin A deficiency results in decreased expression of COX3 mRNA CTD PMID:12163651 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO Vitamin A results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Vitamin A results in decreased expression of MYC mRNA CTD PMID:17219422 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Vitamin A affects the reaction [NCOA1 protein binds to PCK1 promoter] CTD PMID:16317119 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Neurog3 neurogenin 3 decreases expression ISO Vitamin A results in decreased expression of NEUROG3 mRNA CTD PMID:30944279 NCBI chr20:30,079,780...30,081,262
Ensembl chr20:30,079,780...30,081,262 		JBrowse link
G Nkx2-1 NK2 homeobox 1 multiple interactions ISO
EXP		 Vitamin A inhibits the reaction [nitrofen results in decreased expression of NKX2-1 mRNA]
Vitamin A inhibits the reaction [nitrofen results in decreased expression of NKX2-1 protein]		 CTD PMID:16490937 PMID:16863852 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Vitamin A deficiency results in increased expression of NOS2 CTD PMID:16036340 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression EXP Vitamin A deficiency results in increased expression of NOS3 CTD PMID:16036340 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases response to substance ISO NPY1R protein results in increased susceptibility to Vitamin A CTD PMID:17400914 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased abundance of Vitamin A] CTD PMID:31449830 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nrgn neurogranin affects expression EXP Vitamin A affects the expression of NRGN mRNA CTD PMID:14529804 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP Vitamin A deficiency results in decreased expression of ODC1 mRNA CTD PMID:12163651 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Vitamin A results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Oprm1 opioid receptor, mu 1 affects expression EXP Vitamin A affects the expression of OPRM1 mRNA; Vitamin A affects the expression of OPRM1 protein CTD PMID:17289162 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pax3 paired box 3 multiple interactions EXP Vitamin A inhibits the reaction [nitrofen results in decreased expression of PAX3 mRNA] CTD PMID:16481245 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 affects expression
multiple interactions		 ISO Vitamin A affects the expression of PCK1 mRNA
[Tretinoin co-treated with Alitretinoin] affects the reaction [Vitamin A affects the expression of PCK1 mRNA]; Vitamin A affects the reaction [H3F4 protein modified form binds to PCK1 promoter]; Vitamin A affects the reaction [NCOA1 protein binds to PCK1 promoter]; Vitamin A affects the reaction [PPARA protein binds to PCK1 promoter]; Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter]		 CTD PMID:16317119 PMID:16713227 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of PDX1 mRNA CTD PMID:17244017 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Pomc proopiomelanocortin increases expression EXP Vitamin A results in increased expression of POMC protein CTD PMID:17373634 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Vitamin A affects the reaction [PPARA protein binds to PCK1 promoter] CTD PMID:16713227 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression		 EXP Vitamin A inhibits the reaction [Safflower Oil results in increased expression of PPARG mRNA]
Vitamin A results in increased expression of PPARG mRNA		 CTD PMID:15203375 PMID:16180333 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter] CTD PMID:16317119 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppy pancreatic polypeptide multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of PPY mRNA CTD PMID:17244017 NCBI chr10:87,054,747...87,056,044
Ensembl chr10:87,054,756...87,055,455 		JBrowse link
G Prm1 protamine 1 decreases expression ISO Vitamin A results in decreased expression of PRM1 mRNA CTD PMID:30944279 NCBI chr10:4,871,817...4,872,312 JBrowse link
G Ptf1a pancreas associated transcription factor 1a multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of PTF1A mRNA CTD PMID:17244017 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135 		JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO Vitamin A binds to PTGDS protein CTD PMID:16461020 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Vitamin A deficiency results in increased expression of PTGS2 CTD PMID:16036340 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 multiple interactions EXP Vitamin A affects the localization of and affects the phosphorylation of PTPN6 protein CTD PMID:15963505 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions
increases expression		 ISO
EXP		 [Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA
[Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RARA protein; [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter]
Vitamin A results in increased expression of RARA mRNA
Vitamin A deficiency results in increased expression of RARA mRNA
[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA]		 CTD PMID:7519440 PMID:16397886 PMID:17034753 PMID:17225872 PMID:17244623 More... NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta decreases expression
affects expression
multiple interactions
increases expression		 ISO
EXP		 Vitamin A results in decreased expression of RARB mRNA
Vitamin A affects the expression of RARB mRNA
Vitamin A deficiency results in decreased expression of RARB mRNA
[R 115866 co-treated with Vitamin A] results in increased expression of RARB mRNA; Tretinoin inhibits the reaction [Vitamin A affects the expression of RARB mRNA]; Vitamin A inhibits the reaction [Safflower Oil results in decreased expression of RARB mRNA]
Vitamin A results in increased expression of RARB mRNA		 CTD PMID:7519440 PMID:14529804 PMID:15203375 PMID:15754000 PMID:16530976 More... NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rarg retinoic acid receptor, gamma multiple interactions ISO RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA] CTD PMID:16397886 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO Vitamin A results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978 		JBrowse link
G Rbp1 retinol binding protein 1 increases uptake
increases abundance
multiple interactions
affects expression
increases expression		 ISO
EXP		 RBP1 protein results in increased uptake of Vitamin A
RBP1 gene mutant form results in increased abundance of Vitamin A
[RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNA
Vitamin A affects the expression of RBP1 mRNA
Vitamin A results in increased expression of RBP1 mRNA		 CTD PMID:12576510 PMID:16150442 PMID:16793012 PMID:21670153 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rbp2 retinol binding protein 2 multiple interactions ISO [RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNA CTD PMID:21670153 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473 		JBrowse link
G Rbp4 retinol binding protein 4 affects binding
multiple interactions
increases secretion
decreases secretion		 ISO Vitamin A binds to RBP4 protein
Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein
Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]; Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein
Vitamin A results in increased secretion of RBP4 protein
Vitamin A deficiency results in decreased secretion of RBP4 protein		 CTD PMID:16461020 PMID:16762690 PMID:18316031 PMID:21591606 PMID:22001960 More... NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Rdh10 retinol dehydrogenase 10 increases oxidation ISO RDH10 protein results in increased oxidation of Vitamin A CTD PMID:17473173 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Rdh11 retinol dehydrogenase 11 increases oxidation ISO RDH11 protein results in increased oxidation of Vitamin A CTD PMID:16968212 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rdh12 retinol dehydrogenase 12 increases chemical synthesis ISO RDH12 protein results in increased chemical synthesis of Vitamin A CTD PMID:16269441 NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388 		JBrowse link
G Rdh5 retinol dehydrogenase 5 increases oxidation ISO RDH5 protein results in increased oxidation of Vitamin A CTD PMID:16968212 NCBI chr 7:1,341,172...1,346,863
Ensembl chr 7:1,340,934...1,351,558 		JBrowse link
G Ret ret proto-oncogene multiple interactions EXP [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RET protein; [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter] CTD PMID:32526256 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Retn resistin decreases expression ISO Vitamin A results in decreased expression of RETN mRNA CTD PMID:15047602 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression		 EXP [perillyl alcohol co-treated with Vitamin A] results in increased expression of RHOA mRNA
Vitamin A results in increased expression of RHOA mRNA		 CTD PMID:15959631 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhob ras homolog family member B multiple interactions
increases expression		 EXP [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB mRNA; [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB protein
Vitamin A results in increased expression of RHOB mRNA; Vitamin A results in increased expression of RHOB protein		 CTD PMID:15959631 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Rora RAR-related orphan receptor A multiple interactions EXP Vitamin A deficiency promotes the reaction [Valproic Acid results in decreased expression of RORA protein] CTD PMID:33991534 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 increases chemical synthesis
increases metabolic processing		 ISO RPE65 protein results in increased chemical synthesis of Vitamin A
RPE65 protein results in increased metabolism of Vitamin A		 CTD PMID:16150724 PMID:16828753 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [Cryptoxanthins co-treated with Vitamin A] results in increased expression of RUNX2 mRNA CTD PMID:15962303 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
increases expression		 ISO
EXP		 [Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA
Vitamin A results in increased expression of RXRA mRNA
Vitamin A results in increased expression of RXRA protein		 CTD PMID:16180333 PMID:17219422 PMID:17244623 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta affects expression EXP Vitamin A affects the expression of RXRB mRNA CTD PMID:14529804 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Rxrg retinoid X receptor gamma affects expression
decreases expression
increases expression		 EXP
ISO		 Vitamin A affects the expression of RXRG mRNA
Vitamin A results in decreased expression of RXRG mRNA
Vitamin A results in increased expression of RXRG protein		 CTD PMID:14529804 PMID:17219422 PMID:30944279 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 increases oxidation
increases metabolic processing		 ISO SDR16C5 protein results in increased oxidation of Vitamin A
SDR16C5 protein results in increased metabolism of Vitamin A		 CTD PMID:18926804 PMID:27793605 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970 		JBrowse link
G Sftpb surfactant protein B multiple interactions EXP
ISO		 Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPB mRNA]; Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPB protein] CTD PMID:11588001 PMID:16490937 PMID:16863852 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpc surfactant protein C multiple interactions
decreases expression		 EXP Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPC mRNA]
Vitamin A results in decreased expression of SFTPC protein		 CTD PMID:11588001 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in decreased expression of SHH mRNA CTD PMID:17244017 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
increases expression		 ISO Vitamin A promotes the reaction [Corticosterone results in increased expression of SLC1A2 protein]
Vitamin A results in increased expression of SLC1A2 protein		 CTD PMID:17138558 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression EXP Vitamin A deficiency results in decreased expression of SLC30A1 protein CTD PMID:12421840 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910 		JBrowse link
G Slc30a2 solute carrier family 30 member 2 multiple interactions EXP [Zinc deficiency co-treated with Vitamin A deficiency] results in increased expression of SLC30A2 mRNA CTD PMID:12421840 NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956 		JBrowse link
G Slc30a4 solute carrier family 30 member 4 increases expression EXP Vitamin A deficiency results in increased expression of SLC30A4 mRNA; Vitamin A deficiency results in increased expression of SLC30A4 protein CTD PMID:12421840 NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306 		JBrowse link
G Snca synuclein alpha increases expression EXP Vitamin A results in increased expression of SNCA protein CTD PMID:22274401 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sncb synuclein, beta decreases expression EXP Vitamin A results in decreased expression of SNCB protein CTD PMID:22274401 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012 		JBrowse link
G Sod1 superoxide dismutase 1 increases activity EXP Vitamin A results in increased activity of SOD1 protein CTD PMID:22274401 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases activity EXP Vitamin A results in increased activity of SOD2 protein CTD PMID:22274401 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox17 SRY-box transcription factor 17 multiple interactions ISO [Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA CTD PMID:17244017 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions ISO [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA] CTD PMID:16397886 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation		 EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] CTD PMID:16510265 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sst somatostatin multiple interactions
affects expression		 ISO
EXP		 [Vitamin A co-treated with INHBA protein] results in increased expression of SST mRNA
Vitamin A affects the expression of SST protein		 CTD PMID:16757122 PMID:17244017 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression EXP Vitamin A affects the expression of STAT3 protein CTD PMID:15963505 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions EXP Vitamin A affects the phosphorylation of and affects the localization of STAT5A protein CTD PMID:15963505 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 multiple interactions
increases transport		 ISO [STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin A
STRA6 protein results in increased transport of Vitamin A		 CTD PMID:18316031 NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860 		JBrowse link
G Stra8 stimulated by retinoic acid 8 increases expression ISO Vitamin A results in increased expression of STRA8 mRNA CTD PMID:16461896 NCBI chr 4:63,601,443...63,624,777
Ensembl chr 4:63,601,604...63,624,771 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO Vitamin A results in decreased expression of SYCP3 mRNA CTD PMID:30944279 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511 		JBrowse link
G Tfrc transferrin receptor decreases expression
increases expression		 ISO
EXP		 Vitamin A results in decreased expression of TFRC protein
Vitamin A deficiency results in increased expression of TFRC mRNA; Vitamin A deficiency results in increased expression of TFRC protein		 CTD PMID:16960172 PMID:22154532 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP Vitamin A deficiency results in increased expression of TGFA mRNA CTD PMID:7519440 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO Vitamin A results in increased expression of TGFB3 mRNA CTD PMID:17225872 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO Vitamin A results in decreased expression of TGFBR1 mRNA CTD PMID:17225872 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Vitamin A results in increased expression of TGFBR2 mRNA CTD PMID:17225872 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgm2 transglutaminase 2 increases expression
affects expression		 ISO
EXP		 Vitamin A results in increased expression of TGM2 mRNA
Vitamin A affects the expression of TGM2 mRNA		 CTD PMID:14529804 PMID:17034753 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO Vitamin A results in increased expression of TLR2 mRNA CTD PMID:17033190 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO Vitamin A results in increased expression of TLR4 mRNA CTD PMID:17033190 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmem245 transmembrane protein 245 decreases expression EXP Vitamin A deficiency results in decreased expression of TMEM245 mRNA CTD PMID:12163651 NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763 		JBrowse link
G Tnf tumor necrosis factor affects secretion
increases expression		 EXP Vitamin A affects the secretion of TNF protein
Vitamin A results in increased expression of TNF mRNA; Vitamin A results in increased expression of TNF protein		 CTD PMID:15135310 PMID:17289162 PMID:22274401 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tob1 transducer of ErbB-2.1 multiple interactions
increases expression		 ISO CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA] CTD PMID:17234770 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Vitamin A results in increased expression of TPI1 mRNA alternative form CTD PMID:8793052 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Ttr transthyretin multiple interactions ISO Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein] CTD PMID:21591606 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ubc ubiquitin C increases expression EXP Vitamin A deficiency results in increased expression of UBC mRNA CTD PMID:12163651 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of UCHL1 protein CTD PMID:32526256 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP LEP gene mutant form promotes the reaction [Vitamin A results in increased expression of UCP1 mRNA] CTD PMID:16493122 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP Vitamin A inhibits the reaction [Triiodothyronine results in decreased expression of UGT1A1 mRNA] CTD PMID:11299074 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
decreases expression		 EXP Vitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA]
Vitamin A deficiency results in decreased expression of UGT1A6 mRNA		 CTD PMID:11299074 PMID:12163651 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
all-trans-4-oxoretinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 affects expression ISO 4-oxoretinol affects the expression of CDH1 mRNA CTD PMID:17034753 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO 4-oxoretinol results in increased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO 4-oxoretinol results in increased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO 4-oxoretinol results in increased expression of CRABP2 mRNA CTD PMID:17034753 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects chemical synthesis ISO CYP26A1 protein affects the chemical synthesis of 4-oxoretinol CTD PMID:10557354 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 4-oxoretinol results in decreased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Foxa1 forkhead box A1 increases expression ISO 4-oxoretinol results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO 4-oxoretinol results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO 4-oxoretinol results in increased expression of ITGAM protein CTD PMID:9581846 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Ivl involucrin increases expression ISO 4-oxoretinol results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Krt18 keratin 18 increases expression ISO 4-oxoretinol results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt19 keratin 19 increases expression ISO 4-oxoretinol results in increased expression of KRT19 mRNA CTD PMID:17034753 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt7 keratin 7 increases expression ISO 4-oxoretinol results in increased expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Krt8 keratin 8 increases expression ISO 4-oxoretinol results in increased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO 4-oxoretinol results in decreased expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Meis1 Meis homeobox 1 increases expression ISO 4-oxoretinol results in increased expression of MEIS1 mRNA CTD PMID:17034753 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO 4-oxoretinol results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696 		JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO 4-oxoretinol results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO 4-oxoretinol results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO 4-oxoretinol results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO 4-oxoretinol results in increased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO 4-oxoretinol results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978 		JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO 4-oxoretinol results in increased expression of TGM2 mRNA CTD PMID:17034753 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
all-trans-retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP retinol palmitate results in increased activity of CAT protein CTD PMID:20679000 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:17377406 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1RN protein] CTD PMID:17377406 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Lipe lipase E, hormone sensitive type increases hydrolysis
multiple interactions		 ISO LIPE protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]		 CTD PMID:16741517 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein]; retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein]
retinol palmitate results in increased expression of MMP9 mRNA		 CTD PMID:17164434 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Plin3 perilipin 3 multiple interactions ISO PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]; PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] CTD PMID:16741517 NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 increases hydrolysis
multiple interactions		 ISO PNPLA4 protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate]		 CTD PMID:16741517 NCBI chr  X:42,313,554...42,318,451
Ensembl chr  X:42,305,373...42,318,552 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP retinol palmitate results in increased expression of SCARB1 mRNA CTD PMID:17299104 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
retinyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B increases expression ISO retinol acetate results in increased expression of ACVR2B mRNA CTD PMID:16772331 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions		 ISO retinol acetate results in decreased expression of ADIPOQ mRNA
NR1I3 protein affects the reaction [retinol acetate results in decreased expression of ADIPOQ mRNA]		 CTD PMID:31449830 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Alb albumin affects binding ISO retinol acetate binds to ALB protein CTD PMID:17217919 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Apoe apolipoprotein E increases expression ISO retinol acetate results in increased expression of APOE mRNA CTD PMID:16772331 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member increases expression ISO retinol acetate results in increased expression of BCAR1 mRNA CTD PMID:16772331 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO retinol acetate results in increased expression of BMP4 mRNA CTD PMID:16772331 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression ISO retinol acetate results in increased expression of BMP7 mRNA CTD PMID:16772331 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Calm1 calmodulin 1 increases expression ISO retinol acetate results in increased expression of CALM1 mRNA CTD PMID:16772331 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Cbl Cbl proto-oncogene increases expression ISO retinol acetate results in increased expression of CBL mRNA CTD PMID:16772331 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Ccnb2 cyclin B2 increases expression ISO retinol acetate results in increased expression of CCNB2 mRNA CTD PMID:16772331 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 increases expression ISO retinol acetate results in increased expression of CCND1 mRNA CTD PMID:16772331 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 increases expression ISO retinol acetate results in increased expression of CCNE1 mRNA CTD PMID:16772331 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cd36 CD36 molecule decreases expression
multiple interactions		 ISO retinol acetate results in decreased expression of CD36 mRNA
NR1I3 protein affects the reaction [retinol acetate results in decreased expression of CD36 mRNA]		 CTD PMID:31449830 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdx2 caudal type homeo box 2 increases expression ISO retinol acetate results in increased expression of CDX2 mRNA CTD PMID:16772331 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO retinol acetate results in increased expression of CKS2 mRNA CTD PMID:16772331 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Crk CRK proto-oncogene, adaptor protein increases expression ISO retinol acetate results in increased expression of CRK mRNA CTD PMID:16772331 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 increases expression ISO retinol acetate results in increased expression of CSNK2A1 mRNA CTD PMID:16772331 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Ctsb cathepsin B increases expression ISO retinol acetate results in increased expression of CTSB mRNA CTD PMID:16772331 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsd cathepsin D increases expression ISO retinol acetate results in increased expression of CTSD mRNA CTD PMID:16772331 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO retinol acetate results in decreased expression of CYP1A1 mRNA CTD PMID:28123100 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO [retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 mRNA; [retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 protein; BMS453 inhibits the reaction [retinol acetate results in increased expression of CYP26A1 mRNA]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 mRNA]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 protein]; NR1I3 protein affects the reaction [retinol acetate results in increased expression of CYP26A1 mRNA] CTD PMID:16322074 PMID:31449830 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression		 ISO [bisphenol A co-treated with retinol acetate] results in increased expression of CYP2B10 mRNA
retinol acetate results in decreased expression of CYP2B10 mRNA		 CTD PMID:28123100 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA CTD PMID:28123100 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dcn decorin increases expression ISO retinol acetate results in increased expression of DCN mRNA CTD PMID:16772331 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dlx3 distal-less homeobox 3 increases expression ISO retinol acetate results in increased expression of DLX3 mRNA CTD PMID:16772331 NCBI chr10:80,064,489...80,069,891
Ensembl chr10:80,064,489...80,069,872 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO retinol acetate results in increased expression of DNAJC3 mRNA CTD PMID:16772331 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G E2f3 E2F transcription factor 3 increases expression ISO retinol acetate results in increased expression of E2F3 mRNA CTD PMID:16772331 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein increases expression ISO retinol acetate results in increased expression of EI24 mRNA CTD PMID:16772331 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Eng endoglin increases expression ISO retinol acetate results in increased expression of ENG mRNA CTD PMID:16772331 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO retinol acetate results in increased expression of ETS2 mRNA CTD PMID:16772331 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 increases expression ISO retinol acetate results in increased expression of EYA2 mRNA CTD PMID:16772331 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO retinol acetate results in increased expression of FGFR3 mRNA CTD PMID:16772331 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 multiple interactions
decreases expression		 ISO [bisphenol A co-treated with retinol acetate] results in decreased expression of FMO3 mRNA
retinol acetate results in decreased expression of FMO3 mRNA		 CTD PMID:28123100 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Foxg1 forkhead box G1 increases expression ISO retinol acetate results in increased expression of FOXG1 mRNA CTD PMID:16772331 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607 		JBrowse link
G Frzb frizzled-related protein increases expression ISO retinol acetate results in increased expression of FRZB mRNA CTD PMID:16772331 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fxn frataxin increases expression ISO retinol acetate results in increased expression of FXN mRNA CTD PMID:16772331 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Fzd3 frizzled class receptor 3 increases expression ISO retinol acetate results in increased expression of FZD3 mRNA CTD PMID:16772331 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369 		JBrowse link
G Fzd6 frizzled class receptor 6 increases expression ISO retinol acetate results in increased expression of FZD6 mRNA CTD PMID:16772331 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO retinol acetate results in increased expression of GADD45A mRNA CTD PMID:16772331 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO retinol acetate results in increased expression of GAPDH mRNA CTD PMID:16772331 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO retinol acetate results in increased expression of HES1 mRNA CTD PMID:16772331 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO retinol acetate results in increased expression of HPRT1 mRNA CTD PMID:16772331 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO retinol acetate results in increased expression of HSPA4L mRNA CTD PMID:16772331 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO retinol acetate results in increased expression of HSPH1 mRNA CTD PMID:16772331 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO retinol acetate results in increased expression of ID3 mRNA CTD PMID:16772331 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Il4 interleukin 4 increases expression ISO retinol acetate results in increased expression of IL4 protein CTD PMID:11444878 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 affects response to substance
increases expression		 ISO IL5 protein affects the susceptibility to retinol acetate
retinol acetate results in increased expression of IL5 protein		 CTD PMID:11444878 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha affects response to substance ISO IL5RA protein affects the susceptibility to retinol acetate CTD PMID:11444878 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Il6 interleukin 6 increases expression ISO retinol acetate results in increased expression of IL6 protein CTD PMID:11444878 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO retinol acetate results in increased expression of JUND mRNA CTD PMID:16772331 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Kif1b kinesin family member 1B increases expression ISO retinol acetate results in increased expression of KIF1B mRNA CTD PMID:16772331 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Kl Klotho increases expression ISO retinol acetate results in increased expression of KL mRNA CTD PMID:16772331 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Lama5 laminin subunit alpha 5 increases expression ISO retinol acetate results in increased expression of LAMA5 mRNA CTD PMID:16772331 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451 		JBrowse link
G Laptm4a lysosomal protein transmembrane 4 alpha increases expression ISO retinol acetate results in increased expression of LAPTM4A mRNA CTD PMID:16772331 NCBI chr 6:31,719,287...31,737,023
Ensembl chr 6:31,718,976...31,737,020 		JBrowse link
G Lifr LIF receptor subunit alpha increases expression ISO retinol acetate results in increased expression of LIFR mRNA CTD PMID:16772331 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Lrat lecithin retinol acyltransferase multiple interactions ISO [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in decreased expression of CYP2C39 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP4A10 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of MGST1 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of UGT1A1 mRNA; retinol acetate inhibits the reaction [LRAT gene mutant form results in decreased susceptibility to Thioacetamide] CTD PMID:24614237 PMID:28123100 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Ltbr lymphotoxin beta receptor increases expression ISO retinol acetate results in increased expression of LTBR mRNA CTD PMID:16772331 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 increases expression ISO retinol acetate results in increased expression of MAP3K3 mRNA CTD PMID:16772331 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression ISO retinol acetate results in increased expression of MAPK14 mRNA CTD PMID:16772331 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression ISO retinol acetate results in increased expression of MAPKAPK2 mRNA CTD PMID:16772331 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO retinol acetate results in increased expression of MET mRNA CTD PMID:16772331 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression
multiple interactions		 ISO retinol acetate results in increased expression of MGST1 mRNA
[LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of MGST1 mRNA		 CTD PMID:28123100 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO retinol acetate results in increased expression of MMP2 mRNA CTD PMID:16772331 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Msx1 msh homeobox 1 increases expression ISO retinol acetate results in increased expression of MSX1 mRNA CTD PMID:16772331 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Msx2 msh homeobox 2 increases expression ISO retinol acetate results in increased expression of MSX2 mRNA CTD PMID:16772331 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor increases expression ISO retinol acetate results in increased expression of MYCN mRNA CTD PMID:16772331 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Myo1b myosin Ib increases expression ISO retinol acetate results in increased expression of MYO1B mRNA CTD PMID:16772331 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO retinol acetate results in increased expression of NFKBIA mRNA CTD PMID:16772331 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nid1 nidogen 1 increases expression ISO retinol acetate results in increased expression of NID1 mRNA CTD PMID:16772331 NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267 		JBrowse link
G Notch1 notch receptor 1 increases expression ISO retinol acetate results in increased expression of NOTCH1 mRNA CTD PMID:16772331 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 increases expression ISO retinol acetate results in increased expression of NOTCH2 mRNA CTD PMID:16772331 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 mRNA]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP26A1 protein]; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of PPARG mRNA]; NR1I3 protein affects the reaction [retinol acetate results in decreased expression of ADIPOQ mRNA]; NR1I3 protein affects the reaction [retinol acetate results in decreased expression of CD36 mRNA]; NR1I3 protein affects the reaction [retinol acetate results in increased expression of CYP26A1 mRNA] CTD PMID:31449830 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO retinol acetate results in increased expression of PEA15A mRNA CTD PMID:16772331 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO retinol acetate results in increased expression of PHGDH mRNA CTD PMID:16772331 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO retinol acetate results in increased expression of PIK3R1 mRNA CTD PMID:16772331 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of PPARG mRNA; NR1I3 protein affects the reaction [[retinol acetate co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of PPARG mRNA] CTD PMID:31449830 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Psen2 presenilin 2 increases expression ISO retinol acetate results in increased expression of PSEN2 mRNA CTD PMID:16772331 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 increases expression ISO retinol acetate results in increased expression of PTPN13 mRNA CTD PMID:16772331 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO retinol acetate results in increased expression of RAD50 mRNA CTD PMID:16772331 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 increases expression ISO retinol acetate results in increased expression of RANGAP1 mRNA CTD PMID:16772331 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438 		JBrowse link
G Rbp4 retinol binding protein 4 increases expression ISO retinol acetate results in increased expression of RBP4 protein CTD PMID:31449830 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 increases expression ISO retinol acetate results in increased expression of ROR1 mRNA CTD PMID:16772331 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO retinol acetate results in increased expression of RXRA mRNA CTD PMID:16772331 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO retinol acetate results in increased expression of SATB1 mRNA CTD PMID:16772331 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Sdc1 syndecan 1 increases expression ISO retinol acetate results in increased expression of SDC1 mRNA CTD PMID:16772331 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Sim2 SIM bHLH transcription factor 2 increases expression ISO retinol acetate results in increased expression of SIM2 mRNA CTD PMID:16772331 NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663 		JBrowse link
G Smn1 survival of motor neuron 1, telomeric increases expression ISO retinol acetate results in increased expression of SMN1 mRNA CTD PMID:16772331 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060 		JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression ISO retinol acetate results in increased expression of SNAI1 mRNA CTD PMID:16772331 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO retinol acetate results in increased expression of SNAI2 mRNA CTD PMID:16772331 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO retinol acetate results in increased expression of SQSTM1 mRNA CTD PMID:16772331 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tbx2 T-box transcription factor 2 increases expression ISO retinol acetate results in increased expression of TBX2 mRNA CTD PMID:16772331 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression ISO retinol acetate results in increased expression of TIMP3 mRNA CTD PMID:16772331 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase increases expression ISO retinol acetate results in increased expression of TYRO3 mRNA CTD PMID:16772331 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of UGT1A1 mRNA CTD PMID:28123100 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Wnt11 Wnt family member 11 increases expression ISO retinol acetate results in increased expression of WNT11 mRNA CTD PMID:16772331 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt7b Wnt family member 7B increases expression ISO retinol acetate results in increased expression of WNT7B mRNA CTD PMID:16772331 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta increases expression ISO retinol acetate results in increased expression of YWHAZ mRNA CTD PMID:16772331 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          metabolite 19562
            vitamin A 9952
              all-trans-retinol 286
                all-trans-3,4-didehydroretinol + 0
                all-trans-3-hydroxyretinol 0
                all-trans-4-hydroxyretinol 0
                all-trans-4-oxoretinol 23
                all-trans-retinyl ester + 10
                all-trans-retinyl linoleate 0
                all-trans-retinyl oleate 0
                all-trans-retinyl palmitate 10
                all-trans-retinyl stearate 0
                retinyl acetate 97
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      s-block molecular entity 19681
                        hydrogen molecular entity 19662
                          hydrides 19167
                            organic hydride 18711
                              organic fundamental parent 18711
                                hydrocarbon 18454
                                  terpene 14053
                                    terpenoid 13751
                                      diterpenoid 13043
                                        retinoid 10285
                                          vitamin A 9952
                                            all-trans-retinol 286
                                              all-trans-3,4-didehydroretinol + 0
                                              all-trans-3-hydroxyretinol 0
                                              all-trans-4-hydroxyretinol 0
                                              all-trans-4-oxoretinol 23
                                              all-trans-retinyl ester + 10
                                              all-trans-retinyl linoleate 0
                                              all-trans-retinyl oleate 0
                                              all-trans-retinyl palmitate 10
                                              all-trans-retinyl stearate 0
                                              retinyl acetate 97
paths to the root