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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:L-isoleucine
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Accession:CHEBI:17191 term browser browse the term
Definition:The L-enantiomer of isoleucine.
Synonyms:related_synonym: (2S,3S)-2-amino-3-methylpentanoic acid;   2-Amino-3-methylvaleric acid;   Formula=C6H13NO2;   I;   ISOLEUCINE;   Ile;   InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1;   InChIKey=AGPKZVBTJJNPAG-WHFBIAKZSA-N;   SMILES=OC([C@H]([C@H](CC)C)N)=O;   alpha-amino-beta-methylvaleric acid
 alt_id: CHEBI:13127;   CHEBI:21344;   CHEBI:43290;   CHEBI:43342;   CHEBI:43366;   CHEBI:6255
 xref: Beilstein:1721792;   CAS:73-32-5;   DrugBank:DB00167;   Drug_Central:4129;   ECMDB:ECMDB00172;   Gmelin:486381;   HMDB:HMDB0000172;   KEGG:C00407;   KEGG:D00065;   KNApSAcK:C00001374
 xref_mesh: MESH:D007532
 xref: MetaCyc:ILE;   PDBeChem:ILE;   PMID:14651987;   PMID:16140883;   PMID:17299083;   PMID:17409434;   PMID:22298573;   PMID:24284437;   PMID:24406630;   PMID:24738868;   PMID:24831709;   Reaxys:1721792;   Wikipedia:Isoleucine;   YMDB:YMDB00038
 cyclic_relationship: is_conjugate_acid_of CHEBI:32604;   is_conjugate_base_of CHEBI:32605;   is_enantiomer_of CHEBI:27730;   is_tautomer_of CHEBI:58045


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L-isoleucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine] CTD PMID:22689575 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      application 19735
        refrigerant 18285
          butane 97
            sec-butyl group 1
              isoleucine 1
                L-isoleucine 1
                  (4S)-3(1),4-dihydroxy-L-isoleucine zwitterion 0
                  Asn-Ile 0
                  Asp-Lys-Ile 0
                  DON-10-isoleucine 0
                  Glu-Asp-Ile 0
                  Glu-Glu-Ile 0
                  Glu-Ile 0
                  Glu-Ile-Phe 0
                  Glu-Ile-Ser 0
                  Glu-Ile-Val 0
                  His-Ile 0
                  Ile-Asp 0
                  Ile-His 0
                  Ile-Ile 0
                  Ile-Leu-Trp-Trp 0
                  Ile-Leu-Val-Tyr 0
                  Ile-Lys 0
                  Ile-Thr 0
                  L-isoleucine derivative + 0
                  L-isoleucine residue + 0
                  L-isoleucino group 0
                  L-isoleucyl group 0
                  Pro-Glu-Ile 0
                  Thr-Ile 0
                  Trp-Ile 0
                  Tyr-Ile-Leu 0
                  alpha-Asp-Ile 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    main group molecular entity 19838
                      s-block molecular entity 19698
                        hydrogen molecular entity 19679
                          hydrides 19181
                            inorganic hydride 18192
                              pnictogen hydride 18157
                                nitrogen hydride 18070
                                  azane 17873
                                    ammonia 17898
                                      organic amino compound 17898
                                        amino acid 16074
                                          alpha-amino acid 13947
                                            L-alpha-amino acid 12968
                                              aspartate family amino acid 3676
                                                L-isoleucine 1
                                                  (4S)-3(1),4-dihydroxy-L-isoleucine zwitterion 0
                                                  Asn-Ile 0
                                                  Asp-Lys-Ile 0
                                                  DON-10-isoleucine 0
                                                  Glu-Asp-Ile 0
                                                  Glu-Glu-Ile 0
                                                  Glu-Ile 0
                                                  Glu-Ile-Phe 0
                                                  Glu-Ile-Ser 0
                                                  Glu-Ile-Val 0
                                                  His-Ile 0
                                                  Ile-Asp 0
                                                  Ile-His 0
                                                  Ile-Ile 0
                                                  Ile-Leu-Trp-Trp 0
                                                  Ile-Leu-Val-Tyr 0
                                                  Ile-Lys 0
                                                  Ile-Thr 0
                                                  L-isoleucine derivative + 0
                                                  L-isoleucine residue + 0
                                                  L-isoleucino group 0
                                                  L-isoleucyl group 0
                                                  Pro-Glu-Ile 0
                                                  Thr-Ile 0
                                                  Trp-Ile 0
                                                  Tyr-Ile-Leu 0
                                                  alpha-Asp-Ile 0
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