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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:17alpha-estradiol
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Accession:CHEBI:17160 term browser browse the term
Definition:An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).
Synonyms:related_synonym: (17alpha)-estra-1,3,5(10)-triene-3,17-diol;   1,3,5-estratriene-3,17alpha-diol;   13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol;   17-epiestradiol;   17alpha-oestradiol;   3,17alpha-dihydroxyestra-1,3,5(10)-triene;   3,17alpha-dihydroxyoestra-1,3,5(10)-triene;   Formula=C18H24O2;   InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1;   InChIKey=VOXZDWNPVJITMN-SFFUCWETSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21;   alfatradiol;   alfatradiolum;   alpha-estradiol;   epiestradiol;   epiestrol;   estra-1,3,5(10)-triene-3,17alpha-diol;   estra-1,3,5(10)trien-3,17alpha-diol;   oestra-1,3,5(10)-triene-3,17alpha-diol
 alt_id: CHEBI:14217;   CHEBI:23961;   CHEBI:4862
 xref: Beilstein:2698044;   CAS:57-91-0;   Chemspider:61840;   FooDB:FDB011524;   Gmelin:2190991;   HMDB:HMDB0000429;   KEGG:C02537;   KEGG:D07121;   LINCS:LSM-36371;   LIPID_MAPS_instance:LMST02010029;   MetaCyc:CPD-351;   PMID:10533159;   PMID:10977945;   PMID:11379378;   PMID:11410806;   PMID:12115026;   PMID:12234624;   PMID:15698550;   PMID:15947006;   PMID:16042770;   PMID:1810267;   PMID:18644750;   PMID:19093730;   PMID:1920120;   PMID:20451236;   PMID:22581453;   PMID:24245565;   PMID:24564600;   PMID:28877759;   PMID:7925599;   PMID:9457484;   Wikipedia:17%CE%B1-Estradiol


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17alpha-estradiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 affects binding EXP 17alpha-estradiol binds to Esr2 protein RGD PMID:9048584 RGD:8694130 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          drug 19532
            protective agent 18242
              geroprotector 17388
                17alpha-estradiol 1
                  17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                  17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                  17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                  17alpha-estradiol 3-glucosiduronic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic polycyclic compound 17291
                                  steroid 14716
                                    hydroxy steroid 14466
                                      3-hydroxy steroid 12807
                                        phenolic steroid 11312
                                          estradiol 11308
                                            17alpha-estradiol 1
                                              17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                                              17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                                              17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                                              17alpha-estradiol 3-glucosiduronic acid 0
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