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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glyceraldehyde 3-phosphate
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Accession:CHEBI:17138 term browser browse the term
Definition:An aldotriose phosphate that is the 3-phospho derivative of glyceraldehyde. It is an important metabolic intermediate in several central metabolic pathways in all organisms.
Synonyms:exact_synonym: 2-hydroxy-3-oxopropyl dihydrogen phosphate
 related_synonym: 2-hydroxy-3-(phosphonooxy)propanal;   3-phosphoglyceraldehyde;   DL-Glyceraldehyde 3-phosphate;   Formula=C3H7O6P;   GAP;   Glycerinaldehyd-3-phosphat;   Glyzerinaldehyd-3-phosphat;   InChI=1S/C3H7O6P/c4-1-3(5)2-9-10(6,7)8/h1,3,5H,2H2,(H2,6,7,8);   InChIKey=LXJXRIRHZLFYRP-UHFFFAOYSA-N;   SMILES=[H]C(=O)C(O)COP(O)(O)=O;   gliceraldehido-3-fosfato;   glyceraldehyde 3-(dihydrogen phosphate)
 alt_id: CHEBI:14333;   CHEBI:5446
 xref: Beilstein:1725008;   CAS:142-10-9;   CAS:591-59-3;   DrugBank:DB02263;   HMDB:HMDB0001112;   KEGG:C00661;   KNApSAcK:C00007285
 xref_mesh: MESH:D005986
 xref: MetaCyc:CPD0-2032;   Reaxys:1725008;   Wikipedia:3-phosphoglyceraldehyde
 cyclic_relationship: is_conjugate_acid_of CHEBI:58027



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glyceraldehyde 3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
decreases abundance
ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Glyceraldehyde 3-Phosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Glyceraldehyde 3-Phosphate]
PF-06840003 inhibits the reaction [APP protein mutant form results in decreased abundance of Glyceraldehyde 3-Phosphate]
CTD PMID:39172838 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Fbp1 fructose-bisphosphatase 1 multiple interactions ISO [Enzyme Inhibitors results in decreased activity of FBP1 protein] which results in decreased abundance of Glyceraldehyde 3-Phosphate metabolite CTD PMID:31974165 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO [GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog; Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]; Adenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]; NAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]; NADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
decreases abundance
ISO [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Glyceraldehyde 3-Phosphate; PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Glyceraldehyde 3-Phosphate]
PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Glyceraldehyde 3-Phosphate]
CTD PMID:39172838 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 multiple interactions
decreases chemical synthesis
ISO PFKFB1 gene mutant form inhibits the reaction [Metformin results in increased abundance of Glyceraldehyde 3-Phosphate metabolite]
PFKFB1 gene mutant form results in decreased chemical synthesis of Glyceraldehyde 3-Phosphate metabolite
CTD PMID:31974165 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Glyceraldehyde 3-Phosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Glyceraldehyde 3-Phosphate] CTD PMID:39172838 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        solvent 17252
          formic acid 9096
            formyl group 9053
              aldehyde 9053
                glyceraldehyde 3-phosphate 6
                  D-glyceraldehyde 3-phosphate 0
                  L-glyceraldehyde 3-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      chalcogen 19598
                        oxygen atom 19570
                          oxygen molecular entity 19570
                            hydroxides 19374
                              oxoacid 18808
                                pnictogen oxoacid 14987
                                  phosphorus oxoacid 14587
                                    phosphoric acids 13935
                                      phosphoric acid 13935
                                        phosphoric acid derivative 13817
                                          phosphate 13843
                                            organic phosphate 13816
                                              carbohydrate phosphate 1964
                                                phospho sugar 1809
                                                  aldose phosphate 1714
                                                    aldotriose phosphate 4
                                                      glyceraldehyde 3-phosphate 6
                                                        D-glyceraldehyde 3-phosphate 0
                                                        L-glyceraldehyde 3-phosphate 0
paths to the root