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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of BAX protein] |
CTD |
PMID:34227456 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO EXP |
royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] royal jelly inhibits the reaction [Fluorides results in increased expression of BCL2 protein] |
CTD |
PMID:30896085 PMID:34227456 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of BDNF protein] |
CTD |
PMID:34227456 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO EXP |
royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP3 protein] |
CTD |
PMID:30896085 PMID:34227456 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp6 |
caspase 6 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP6 protein] |
CTD |
PMID:34227456 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP9 protein] |
CTD |
PMID:34227456 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions |
EXP ISO |
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; royal jelly inhibits the reaction [Fluorides results in decreased activity of CAT protein] royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein] |
CTD |
PMID:20369241 PMID:30896085 PMID:34227456 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [phenylhydrazine affects the expression of CCND1 mRNA] |
CTD |
PMID:35099105 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Paclitaxel results in increased expression of E2F1 mRNA] |
CTD |
PMID:27496854 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases activity affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein] royal jelly results in increased activity of ESR1 protein |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in increased expression of GSK3B protein] |
CTD |
PMID:34227456 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fructose results in increased expression of INS1 protein] |
CTD |
PMID:18981581 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
ISO EXP |
royal jelly inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA] royal jelly inhibits the reaction [Paclitaxel results in decreased expression of MYC mRNA] royal jelly results in decreased expression of MYC mRNA |
CTD |
PMID:27496854 PMID:35099105 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of NFE2L2 protein] |
CTD |
PMID:34227456 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] |
CTD |
PMID:30896085 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in increased expression of RELA protein] |
CTD |
PMID:34227456 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
royal jelly results in increased expression of TFF1 mRNA |
CTD |
PMID:15946813 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] |
CTD |
PMID:30896085 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO EXP |
royal jelly results in increased expression of VEGFA mRNA |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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