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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-phosphoglyceric acid
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Accession:CHEBI:17050 term browser browse the term
Definition:A monophosphoglyceric acid having the phospho group at the 3-position. It is an intermediate in metabolic pathways like glycolysis and calvin cycle.
Synonyms:exact_synonym: 2-hydroxy-3-(phosphonooxy)propanoic acid
 related_synonym: 3-(dihydrogen phosphate)Glycerate;   3-(dihydrogen phosphate)Glyceric acid;   3-Phosphoglycerate;   DL-Glycerate 3-phosphate;   Formula=C3H7O7P;   Glycerate 3-phosphate;   Glyceric acid 3-phosphate;   InChI=1S/C3H7O7P/c4-2(3(5)6)1-10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9);   InChIKey=OSJPPGNTCRNQQC-UHFFFAOYSA-N;   SMILES=OC(COP(O)(O)=O)C(O)=O;   glycerate 3-phosphates
 alt_id: CHEBI:11882;   CHEBI:1659;   CHEBI:24345;   CHEBI:40016
 xref: CAS:820-11-1;   Chemspider:704;   DrugBank:DB04510;   HMDB:HMDB0000807;   KEGG:C00597;   KNApSAcK:C00007286
 xref_mesh: MESH:C005156
 xref: PMID:17439666;   PMID:22735334;   Reaxys:1726829;   Wikipedia:3-Phosphoglyceric_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:132960;   is_conjugate_acid_of CHEBI:57998;   is_conjugate_acid_of CHEBI:88005


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3-phosphoglyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance 		ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 3-phosphoglycerate] CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of 3-phosphoglycerate; PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of 3-phosphoglycerate] CTD PMID:39172838 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        biochemical role 20264
          metabolite 20245
            fundamental metabolite 14805
              3-phosphoglyceric acid 3
                3-phospho-D-glyceric acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      chalcogen 20491
                        oxygen atom 20457
                          oxygen molecular entity 20457
                            hydroxides 20230
                              oxoacid 19289
                                pnictogen oxoacid 15112
                                  phosphorus oxoacid 14667
                                    phosphoric acids 13987
                                      phosphoric acid 13987
                                        phosphoric acid derivative 13899
                                          phosphate 13898
                                            organic phosphate 13898
                                              carbohydrate phosphate 1976
                                                aldonic acid phosphate 7
                                                  phosphoglyceric acid 7
                                                    monophosphoglyceric acid 3
                                                      3-phosphoglyceric acid 3
                                                        3-phospho-D-glyceric acid 0
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