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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzene-1,2,4-triol
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Accession:CHEBI:16971 term browser browse the term
Definition:A benzenetriol carrying hydroxy groups at positions 1, 2 and 4.
Synonyms:related_synonym: 1,2,4-Benzenetriol;   1,2,4-Trihydroxybenzene;   Formula=C6H6O3;   Hydroxyhydroquinone;   Hydroxyquinol;   InChI=1S/C6H6O3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9H;   InChIKey=GGNQRNBDZQJCCN-UHFFFAOYSA-N;   SMILES=Oc1ccc(O)c(O)c1
 alt_id: CHEBI:11136;   CHEBI:13877;   CHEBI:22709;   CHEBI:3026
 xref: CAS:533-73-3;   KEGG:C02814;   KNApSAcK:C00031480
 xref_mesh: MESH:C013038
 xref: MetaCyc:CPD-8130;   PDBeChem:HQN;   PMID:21396889;   PMID:24578277;   PMID:24803113;   UM-BBD_compID:c0264;   Wikipedia:Benzene-1\,2\,4-triol


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benzene-1,2,4-triol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO hydroxyhydroquinone results in increased expression of ABCC1 mRNA CTD PMID:17572062 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Acly ATP citrate lyase increases expression ISO hydroxyhydroquinone results in increased expression of ACLY mRNA CTD PMID:17572062 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Adsl adenylosuccinate lyase decreases expression ISO hydroxyhydroquinone results in decreased expression of ADSL mRNA CTD PMID:17572062 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760 		JBrowse link
G Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 increases expression ISO hydroxyhydroquinone results in increased expression of AREL1 mRNA CTD PMID:17572062 NCBI chr 6:104,560,556...104,617,712
Ensembl chr 6:104,564,986...104,617,628 		JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 decreases expression ISO hydroxyhydroquinone results in decreased expression of ARL6IP5 mRNA CTD PMID:17572062 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO hydroxyhydroquinone results in increased expression of ATF3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of ATF3 mRNA]		 CTD PMID:24530881 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO hydroxyhydroquinone results in increased expression of BACH1 mRNA CTD PMID:17572062 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BCL3 mRNA] CTD PMID:24530881 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BIRC3 mRNA] CTD PMID:24530881 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Casp3 caspase 3 increases activity ISO hydroxyhydroquinone results in increased activity of CASP3 protein CTD PMID:23776099 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO hydroxyhydroquinone results in increased activity of CASP8 protein CTD PMID:23776099 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity ISO hydroxyhydroquinone results in increased activity of CASP9 protein CTD PMID:23776099 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 affects expression ISO hydroxyhydroquinone affects the expression of CCL11 protein CTD PMID:17572062 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression ISO hydroxyhydroquinone affects the expression of CCL2 protein CTD PMID:17572062 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 affects expression ISO hydroxyhydroquinone affects the expression of CCL3 protein CTD PMID:17572062 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
affects expression
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CCL4 mRNA]
hydroxyhydroquinone affects the expression of CCL4 protein		 CTD PMID:17572062 PMID:24530881 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 affects expression ISO hydroxyhydroquinone affects the expression of CCL5 protein CTD PMID:17572062 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CHAC1 mRNA] CTD PMID:24530881 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroxyhydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO hydroxyhydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Cttn cortactin increases expression ISO hydroxyhydroquinone results in increased expression of CTTN mRNA CTD PMID:17572062 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL2 mRNA] CTD PMID:24530881 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroxyhydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:17572062 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO hydroxyhydroquinone results in increased expression of CYP27A1 mRNA CTD PMID:17572062 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone CTD PMID:15051535 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of DDIT4 mRNA] CTD PMID:24530881 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of DGAT2 mRNA] CTD PMID:24530881 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroxyhydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:17572062 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions		 ISO hydroxyhydroquinone results in increased expression of EGR1 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of EGR1 mRNA]		 CTD PMID:24530881 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO hydroxyhydroquinone results in decreased expression of EIF3A mRNA CTD PMID:17572062 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976 		JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L decreases expression ISO hydroxyhydroquinone results in decreased expression of EIF3L mRNA CTD PMID:17572062 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614 		JBrowse link
G Eng endoglin multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ENG mRNA] CTD PMID:24530881 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO hydroxyhydroquinone results in increased expression of ERO1A mRNA CTD PMID:17572062 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Eva1b eva-1 homolog B increases expression ISO hydroxyhydroquinone results in increased expression of EVA1B mRNA CTD PMID:17572062 NCBI chr 5:138,427,088...138,429,602
Ensembl chr 5:138,427,151...138,432,433 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO hydroxyhydroquinone results in increased expression of FAS protein CTD PMID:23776099 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO hydroxyhydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fdxr ferredoxin reductase increases expression ISO hydroxyhydroquinone results in increased expression of FDXR mRNA CTD PMID:17572062 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Gabpb2 GA binding protein transcription factor subunit beta 2 increases expression ISO hydroxyhydroquinone results in increased expression of GABPB2 mRNA CTD PMID:17572062 NCBI chr 2:182,755,304...182,795,368
Ensembl chr 2:182,761,359...182,795,109 		JBrowse link
G Gata1 GATA binding protein 1 multiple interactions
affects methylation		 ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
hydroxyhydroquinone affects the methylation of GATA1 promoter		 CTD PMID:21414390 PMID:30327826 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression		 ISO hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroxyhydroquinone results in decreased expression of GATA2 mRNA		 CTD PMID:21414390 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gga1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 increases expression ISO hydroxyhydroquinone results in increased expression of GGA1 mRNA CTD PMID:17572062 NCBI chr 7:110,436,071...110,451,790
Ensembl chr 7:110,435,062...110,451,789 		JBrowse link
G Gnaz G protein subunit alpha z increases expression ISO hydroxyhydroquinone results in increased expression of GNAZ mRNA CTD PMID:17572062 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta increases expression ISO hydroxyhydroquinone results in increased expression of GP1BB mRNA CTD PMID:17572062 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gypa glycophorin A decreases expression ISO hydroxyhydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
G H2ac18 H2A clustered histone 18 increases expression ISO hydroxyhydroquinone results in increased expression of H2AC18 mRNA CTD PMID:17572062 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2bc8 H2B clustered histone 8 increases expression ISO hydroxyhydroquinone results in increased expression of H2BC8 mRNA CTD PMID:17572062 NCBI chr17:42,708,658...42,709,408 JBrowse link
G Hbb hemoglobin subunit beta multiple interactions ISO Decitabine inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; trichostatin A inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]] CTD PMID:21414390 PMID:30327826 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO hydroxyhydroquinone results in increased expression of HES1 mRNA CTD PMID:17572062 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:24530881 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO hydroxyhydroquinone results in increased expression of HSP90AA1 mRNA CTD PMID:17572062 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO hydroxyhydroquinone results in increased expression of HSPA1A mRNA CTD PMID:17572062 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO hydroxyhydroquinone results in increased expression of HSPA1B mRNA CTD PMID:17572062 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide]; Lipopolysaccharides promotes the reaction [[IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein] CTD PMID:17572062 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 increases expression ISO hydroxyhydroquinone results in increased expression of IL6 protein CTD PMID:17572062 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itga2b integrin subunit alpha 2b increases expression ISO hydroxyhydroquinone results in increased expression of ITGA2B mRNA CTD PMID:17572062 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroxyhydroquinone results in increased expression of ITGB3 mRNA CTD PMID:17572062 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 increases expression ISO hydroxyhydroquinone results in increased expression of JARID2 mRNA CTD PMID:17572062 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of JUN mRNA] CTD PMID:24530881 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnd1 potassium voltage-gated channel subfamily D member 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of KCND1 mRNA CTD PMID:17572062 NCBI chr  X:14,661,688...14,678,745
Ensembl chr  X:14,662,357...14,677,233 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO hydroxyhydroquinone results in increased expression of KEAP1 mRNA CTD PMID:17572062 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLF2 mRNA] CTD PMID:24530881 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klhdc7b kelch domain containing 7B increases expression
multiple interactions		 ISO hydroxyhydroquinone results in increased expression of KLHDC7B mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLHDC7B mRNA]		 CTD PMID:24530881 NCBI chr 7:120,452,081...120,455,737
Ensembl chr 7:120,453,932...120,455,737 		JBrowse link
G Lingo3 leucine rich repeat and Ig domain containing 3 decreases expression
multiple interactions		 ISO hydroxyhydroquinone results in decreased expression of LINGO3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of LINGO3 mRNA]		 CTD PMID:24530881 NCBI chr 7:8,869,025...8,878,431
Ensembl chr 7:8,869,025...8,878,431 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANOS1 mRNA] CTD PMID:24530881 NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANP mRNA] CTD PMID:24530881 NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648 		JBrowse link
G Nck2 NCK adaptor protein 2 increases expression ISO hydroxyhydroquinone results in increased expression of NCK2 mRNA CTD PMID:17572062 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroxyhydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions		 ISO hydroxyhydroquinone results in increased expression of NFKBIA mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of NFKBIA mRNA]		 CTD PMID:24530881 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Pde11a phosphodiesterase 11A multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PDE11A mRNA] CTD PMID:24530881 NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO hydroxyhydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:17572062 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Plin2 perilipin 2 increases expression ISO hydroxyhydroquinone results in increased expression of PLIN2 mRNA CTD PMID:17572062 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Polr1g RNA polymerase I subunit G multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of POLR1G mRNA] CTD PMID:24530881 NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases expression ISO hydroxyhydroquinone results in increased expression of PPP1R12A mRNA CTD PMID:17572062 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Prdm12 PR/SET domain 12 decreases expression
multiple interactions		 ISO hydroxyhydroquinone results in decreased expression of PRDM12 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRDM12 mRNA]		 CTD PMID:24530881 NCBI chr 3:14,928,651...14,943,341
Ensembl chr 3:14,928,628...14,943,331 		JBrowse link
G Prtn3 proteinase 3 multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRTN3 mRNA] CTD PMID:24530881 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
G Prune1 prune exopolyphosphatase 1 increases expression ISO hydroxyhydroquinone results in increased expression of PRUNE1 mRNA CTD PMID:17572062 NCBI chr 2:182,830,575...182,859,972
Ensembl chr 2:182,830,578...182,859,336 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression
multiple interactions		 ISO hydroxyhydroquinone results in decreased expression of PTPN3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PTPN3 mRNA]		 CTD PMID:24530881 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443 		JBrowse link
G Rab22a RAB22A, member RAS oncogene family increases expression ISO hydroxyhydroquinone results in increased expression of RAB22A mRNA CTD PMID:17572062 NCBI chr 3:162,459,727...162,506,129
Ensembl chr 3:162,459,726...162,506,137 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of RELB mRNA] CTD PMID:24530881 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rilp Rab interacting lysosomal protein decreases expression
multiple interactions		 ISO hydroxyhydroquinone results in decreased expression of RILP mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RILP mRNA]		 CTD PMID:24530881 NCBI chr10:60,355,276...60,358,434
Ensembl chr10:60,355,278...60,358,781 		JBrowse link
G Rpl15 ribosomal protein L15 decreases expression ISO hydroxyhydroquinone results in decreased expression of RPL15 mRNA CTD PMID:17572062 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165 		JBrowse link
G Rpl5 ribosomal protein L5 decreases expression ISO hydroxyhydroquinone results in decreased expression of RPL5 mRNA CTD PMID:17572062 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G RT1-Ha RT1 class II, locus Ha decreases expression ISO hydroxyhydroquinone results in decreased expression of HLA-DPA1 mRNA CTD PMID:17572062 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of HLA-DPB1 mRNA CTD PMID:17572062 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618 		JBrowse link
G Rtn4r reticulon 4 receptor decreases expression
multiple interactions		 ISO hydroxyhydroquinone results in decreased expression of RTN4R mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RTN4R mRNA]		 CTD PMID:24530881 NCBI chr11:82,844,309...82,869,251
Ensembl chr11:82,844,309...82,869,466 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of SCIMP mRNA] CTD PMID:24530881 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of SERPINF1 mRNA CTD PMID:17572062 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of SESN2 mRNA] CTD PMID:24530881 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sh3bp2 SH3-domain binding protein 2 increases expression ISO hydroxyhydroquinone results in increased expression of SH3BP2 mRNA CTD PMID:17572062 NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251 		JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of SORL1 mRNA CTD PMID:17572062 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Srsf9 serine and arginine rich splicing factor 9 decreases expression ISO hydroxyhydroquinone results in decreased expression of SRSF9 mRNA CTD PMID:17572062 NCBI chr12:41,278,225...41,284,502
Ensembl chr12:41,275,687...41,284,499 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO hydroxyhydroquinone results in decreased expression of ST3GAL3 mRNA CTD PMID:23776099 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
G Steap3 STEAP3 metalloreductase multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of STEAP3 mRNA] CTD PMID:24530881 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions		 ISO hydroxyhydroquinone results in decreased expression of TFRC protein
hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of TFRC mRNA]		 CTD PMID:21414390 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TLR9 mRNA] CTD PMID:24530881 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmem158 transmembrane protein 158 increases expression ISO hydroxyhydroquinone results in increased expression of TMEM158 mRNA CTD PMID:17572062 NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO hydroxyhydroquinone results in increased expression of TNF mRNA CTD PMID:17572062 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions
increases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of TNFAIP6 mRNA] CTD PMID:24530881 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TNFRSF8 mRNA] CTD PMID:24530881 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO hydroxyhydroquinone results in decreased activity of TOP2A protein CTD PMID:7586126 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Ttll4 tubulin tyrosine ligase like 4 increases expression ISO hydroxyhydroquinone results in increased expression of TTLL4 mRNA CTD PMID:17572062 NCBI chr 9:76,221,659...76,258,219
Ensembl chr 9:76,221,796...76,251,301 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO hydroxyhydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:17572062 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions
decreases expression		 ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ZBTB42 mRNA] CTD PMID:24530881 NCBI chr 6:131,734,257...131,742,459
Ensembl chr 6:131,738,356...131,742,685 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    chemical entity 19909
      molecular entity 19880
        polyatomic entity 19862
          heteroatomic molecular entity 19818
            hydroxides 19374
              organic hydroxy compound 18978
                phenols 18674
                  benzenetriol 2654
                    benzene-1,2,4-triol 106
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      chalcogen 19598
                        oxygen atom 19570
                          oxygen molecular entity 19570
                            hydroxides 19374
                              organic hydroxy compound 18978
                                polyol 11687
                                  triol 6993
                                    benzenetriol 2654
                                      benzene-1,2,4-triol 106
paths to the root