4-nitrophenol - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	4-nitrophenol	go back to main search page
Accession:	CHEBI:16836	browse the term
Definition:	A member of the class of 4-nitrophenols that is phenol in which the hydrogen that is para to the hydroxy group has been replaced by a nitro group.
Synonyms:	related_synonym:	4-Hydroxynitrobenzene; Formula=C6H5NO3; InChI=1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H; InChIKey=BTJIUGUIPKRLHP-UHFFFAOYSA-N; Niphen; PNP; SMILES=Oc1ccc(cc1)[N+]([O-])=O; p-Nitrophenol; p-hydroxynitrobenzene; paranitrophenol
	alt_id:	CHEBI:12034; CHEBI:1913; CHEBI:20457; CHEBI:44390
	xref:	Beilstein:1281877; CAS:100-02-7; DrugBank:DB04417; Gmelin:3311; HMDB:HMDB0001232; KEGG:C00870
	xref_mesh:	MESH:C024836
	xref:	MetaCyc:P-NITROPHENOL; PDBeChem:NPO; PMID:19365648; Reaxys:1281877; UM-BBD_compID:c0086; Wikipedia:4-Nitrophenol
	cyclic_relationship:	is_conjugate_acid_of CHEBI:57917

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Genes (1318)

4-nitrophenol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 1

affects glucuronidation

ABCC1 protein affects the glucuronidation of 4-nitrophenol

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

adhesion G protein-coupled receptor B1

increases expression

4-nitrophenol results in increased expression of ADGRB1 mRNA

NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902

G

aryl hydrocarbon receptor

increases expression

4-nitrophenol results in increased expression of AHR mRNA; 4-nitrophenol results in increased expression of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aldo-keto reductase family 1, member B7

increases expression

4-nitrophenol results in increased expression of AKR1B7 mRNA

NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502

G

albumin

multiple interactions

[4-nitrophenol co-treated with 4-aminophenol co-treated with 4-nitroaniline] results in increased expression of ALB protein
ALB protein binds to and affects the transport of 4-nitrophenol; ALB protein binds to and affects the transport of 4-nitrophenol analog

PMID:8831264 PMID:20429802

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions

[ALDH1A1 protein results in increased oxidation of 4-nitrophenyl acetate] results in increased chemical synthesis of [4-nitrophenol co-treated with Acetic Acid]

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A2

decreases expression

4-nitrophenol results in decreased expression of ALDH1A2 mRNA

NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107

G

anaphase promoting complex subunit 1

decreases expression

4-nitrophenol results in decreased expression of ANAPC1 mRNA

NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273

G

anaphase-promoting complex subunit 5

decreases expression

4-nitrophenol results in decreased expression of ANAPC5 mRNA

NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781

G

anaphase promoting complex subunit 7

increases expression

4-nitrophenol results in increased expression of ANAPC7 mRNA

NCBI chr12:34,131,214...34,160,819
Ensembl chr12:34,133,429...34,160,005

G

apoptotic peptidase activating factor 1

increases expression

4-nitrophenol results in increased expression of APAF1 mRNA

NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540

G

androgen receptor

increases expression

4-nitrophenol results in increased expression of AR mRNA; 4-nitrophenol results in increased expression of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

A-Raf proto-oncogene, serine/threonine kinase

increases expression

4-nitrophenol results in increased expression of ARAF mRNA

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

G

ATR serine/threonine kinase

decreases expression

4-nitrophenol results in decreased expression of ATR mRNA

NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136

G

advillin

increases expression

4-nitrophenol results in increased expression of AVIL mRNA

NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

Quercetin inhibits the reaction [4-nitrophenol results in increased expression of BAX protein]

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression

4-nitrophenol results in decreased expression of BCL2 mRNA

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression
multiple interactions

4-nitrophenol results in decreased expression of BCL2L1 protein
Quercetin inhibits the reaction [4-nitrophenol results in decreased expression of BCL2L1 protein]

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

Bcl2-like 11

increases expression

4-nitrophenol results in increased expression of BCL2L11 mRNA

NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068

G

baculoviral IAP repeat-containing 3

decreases expression

4-nitrophenol results in decreased expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

calcium voltage-gated channel subunit alpha1 C

decreases expression

4-nitrophenol results in decreased expression of CACNA1C mRNA

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

G

carbonic anhydrase 9

decreases expression

4-nitrophenol results in decreased expression of CAR9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

caspase 2

increases expression

4-nitrophenol results in increased expression of CASP2 mRNA

NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379

G

caspase 3

multiple interactions
decreases expression
increases activity

Quercetin inhibits the reaction [4-nitrophenol results in increased activity of CASP3 protein]
4-nitrophenol results in decreased expression of CASP3 mRNA

PMID:23997041 PMID:34673133

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases expression

4-nitrophenol results in increased expression of CASP9 mRNA

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

cyclin D1

decreases expression

4-nitrophenol results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin E1

decreases expression

4-nitrophenol results in decreased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

decreases expression

4-nitrophenol results in decreased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

cyclin G2

increases expression

4-nitrophenol results in increased expression of CCNG2 mRNA

NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830

G

cyclin H

decreases expression

4-nitrophenol results in decreased expression of CCNH mRNA

NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819

G

Cd82 molecule

increases expression

4-nitrophenol results in increased expression of CD82 mRNA

NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809

G

cell division cycle 14B

decreases expression

4-nitrophenol results in decreased expression of CDC14B mRNA

NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235

G

cell division cycle 26

decreases expression

4-nitrophenol results in decreased expression of CDC26 mRNA

NCBI chr 5:75,844,852...75,859,830

G

cell division cycle 6

decreases expression

4-nitrophenol results in decreased expression of CDC6 mRNA

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cyclin-dependent kinase 1

decreases expression

4-nitrophenol results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 14

increases expression

4-nitrophenol results in increased expression of CDK14 mRNA

NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861

G

cyclin-dependent kinase 6

decreases expression

4-nitrophenol results in decreased expression of CDK6 mRNA

NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase inhibitor 1A

increases expression

4-nitrophenol results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

CMT1A duplicated region transcript 4

increases expression

4-nitrophenol results in increased expression of CDRT4 mRNA

NCBI chr10:47,625,470...47,657,493
Ensembl chr10:47,625,470...47,657,493

G

carboxylesterase 1D

affects metabolic processing
multiple interactions
increases chemical synthesis

CES1 protein affects the metabolism of 4-nitrophenol
[CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate] which results in increased chemical synthesis of 4-nitrophenol
CES1 protein results in increased chemical synthesis of 4-nitrophenol

PMID:12837533 PMID:20097249

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

cilia and flagella associated protein 43

increases expression

4-nitrophenol results in increased expression of CFAP43 mRNA

NCBI chr 1:246,625,259...246,712,438
Ensembl chr 1:246,625,262...246,712,443

G

CASP8 and FADD-like apoptosis regulator

decreases expression

4-nitrophenol results in decreased expression of CFLAR mRNA

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

G

checkpoint kinase 1

decreases expression

4-nitrophenol results in decreased expression of CHEK1 mRNA

NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009

G

casein kinase 1, epsilon

decreases expression

4-nitrophenol results in decreased expression of CSNK1E mRNA

NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794

G

cathepsin L

increases expression

4-nitrophenol results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cytochrome P450, family 11, subfamily b, polypeptide 3

increases expression

4-nitrophenol results in increased expression of CYP11B1 mRNA

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases expression

4-nitrophenol results in decreased expression of CYP19A1 mRNA

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
affects expression

4-nitrophenol results in increased expression of CYP1A1 protein
4-nitrophenol affects the expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases hydroxylation

CYP1A2 protein results in increased hydroxylation of 4-nitrophenol

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily C, polypeptide 6

increases hydroxylation

CYP2C19 protein results in increased hydroxylation of 4-nitrophenol

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases metabolic processing
affects binding
increases hydroxylation
increases oxidation
multiple interactions

CYP2E1 protein results in increased metabolism of 4-nitrophenol
4-nitrophenol binds to CYP2E1 protein
CYP2E1 protein results in increased hydroxylation of 4-nitrophenol
CYP2E1 protein results in increased oxidation of 4-nitrophenol
4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]; 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased oxidation of norflurane]; [CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol; Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; ferric-adenosine triphosphate complex inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; IL6 protein promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; notopterol inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; notopterol inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]
2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]; [CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol; Acetone promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; daidzein inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; isobavachalcone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; neobavaisoflavone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; psoralidin inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; pyridine promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]

PMID:1356728 PMID:1538706 PMID:7601153 PMID:8074729 PMID:8117321 More...

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

increases hydroxylation

CYP3A23-3A1 protein results in increased hydroxylation of 4-nitrophenol

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

damage specific DNA binding protein 2

increases expression

4-nitrophenol results in increased expression of DDB2 mRNA

NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631

G

DNA-damage inducible transcript 3

increases expression

4-nitrophenol results in increased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

diablo, IAP-binding mitochondrial protein

decreases expression

4-nitrophenol results in decreased expression of DIABLO mRNA

NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387

G

DLG associated protein 1

increases expression

4-nitrophenol results in increased expression of DLGAP1 mRNA

NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817

G

E2F transcription factor 2

decreases expression

4-nitrophenol results in decreased expression of E2F2 mRNA

NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217

G

E2F transcription factor 4

decreases expression

4-nitrophenol results in decreased expression of E2F4 mRNA

NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806

G

epidermal growth factor receptor

increases expression

4-nitrophenol results in increased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

early growth response 2

decreases expression

4-nitrophenol results in decreased expression of EGR2 mRNA

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

early growth response 3

decreases expression

4-nitrophenol results in decreased expression of EGR3 mRNA

NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627

G

EI24, autophagy associated transmembrane protein

increases expression

4-nitrophenol results in increased expression of EI24 mRNA

NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571

G

endonuclease G

increases expression

4-nitrophenol results in increased expression of ENDOG mRNA

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

endoplasmic reticulum to nucleus signaling 1

decreases expression

4-nitrophenol results in decreased expression of ERN1 mRNA

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

estrogen receptor 1

increases expression
affects expression

4-nitrophenol results in increased expression of ESR1 mRNA; 4-nitrophenol results in increased expression of ESR1 protein
4-nitrophenol affects the expression of ESR1 protein

PMID:24070737 PMID:27172127

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

decreases expression

4-nitrophenol results in decreased expression of ESR2 mRNA

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

Fas associated via death domain

decreases expression

4-nitrophenol results in decreased expression of FADD mRNA

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

G

Fas cell surface death receptor

increases expression

4-nitrophenol results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

F-box protein 32

decreases expression

4-nitrophenol results in decreased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression

4-nitrophenol results in decreased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box O3

increases expression

4-nitrophenol results in increased expression of FOXO3 mRNA

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

forkhead box O4

increases expression

4-nitrophenol results in increased expression of FOXO4 mRNA

NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115

G

glucose-6-phosphatase catalytic subunit 1

increases expression

4-nitrophenol results in increased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

GABA type A receptor-associated protein

decreases expression

4-nitrophenol results in decreased expression of GABARAP mRNA

NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765

G

GABA type A receptor associated protein like 2

decreases expression

4-nitrophenol results in decreased expression of GABARAPL2 mRNA

NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
Ensembl chr 8:39,910,534...39,924,628

G

growth arrest and DNA-damage-inducible, beta

increases expression

4-nitrophenol results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

GTPase, IMAP family member 8

increases expression

4-nitrophenol results in increased expression of GIMAP8 mRNA

NCBI chr 4:77,600,104...77,611,593
Ensembl chr 4:77,600,186...77,611,590

G

GLIS family zinc finger 3

increases expression

4-nitrophenol results in increased expression of GLIS3 mRNA

NCBI chr 1:225,976,029...226,395,849
Ensembl chr 1:225,976,326...226,395,899

G

glycogen synthase kinase 3 beta

decreases expression

4-nitrophenol results in decreased expression of GSK3B mRNA

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione S-transferase alpha 1

increases expression

4-nitrophenol results in increased expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

increases metabolic processing

GSTA2 protein polymorphism results in increased metabolism of 4-nitrophenol

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase, C-terminal domain containing

decreases expression

4-nitrophenol results in decreased expression of GSTCD mRNA

NCBI chr 2:221,499,732...221,591,888
Ensembl chr 2:221,499,083...221,591,857

G

glutathione S-transferase kappa 1

decreases expression

4-nitrophenol results in decreased expression of GSTK1 mRNA

NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase omega 2

increases expression

4-nitrophenol results in increased expression of GSTO2 mRNA

NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866

G

glucoside xylosyltransferase 2

decreases expression

4-nitrophenol results in decreased expression of GXYLT2 mRNA

NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454

G

histone deacetylase 11

increases expression

4-nitrophenol results in increased expression of HDAC11 mRNA

NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405

G

hypoxia inducible factor 3 subunit alpha

decreases expression

4-nitrophenol results in decreased expression of HIF3A mRNA

NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758

G

histone linker H1 domain, spermatid-specific 1

decreases expression

4-nitrophenol results in decreased expression of H1F9 mRNA

NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321

G

high mobility group AT-hook 2

decreases expression

4-nitrophenol results in decreased expression of HMGA2 mRNA

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

G

heme oxygenase 1

increases expression
multiple interactions

4-nitrophenol results in increased expression of HMOX1 mRNA
Quercetin inhibits the reaction [4-nitrophenol results in increased expression of HMOX1 mRNA]

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

HRas proto-oncogene, GTPase

affects glucuronidation

HRAS protein affects the glucuronidation of 4-nitrophenol

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

5-hydroxytryptamine receptor 1B

decreases expression

4-nitrophenol results in decreased expression of HTR1B mRNA

NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549

G

interferon induced with helicase C domain 1

increases expression

4-nitrophenol results in increased expression of IFIH1 mRNA

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

insulin-like growth factor 1

decreases expression

4-nitrophenol results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 5

decreases expression

4-nitrophenol results in decreased expression of IGFBP5 mRNA

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

decreases expression

4-nitrophenol results in decreased expression of IKBKG mRNA

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

G

interleukin 6

multiple interactions
affects expression

IL6 protein promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]
4-nitrophenol affects the expression of IL6 mRNA

PMID:8531136 PMID:34673133

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

insulin 1

decreases expression

4-nitrophenol results in decreased expression of INS1 mRNA

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin receptor

increases expression

4-nitrophenol results in increased expression of INSR mRNA

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

G

immunity-related GTPase M

increases expression

4-nitrophenol results in increased expression of IRGM1 mRNA

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

insulin receptor substrate 1

decreases expression

4-nitrophenol results in decreased expression of IRS1 mRNA

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

integrin subunit alpha 10

decreases expression

4-nitrophenol results in decreased expression of ITGA10 mRNA

NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172

G

inositol 1,4,5-trisphosphate receptor, type 2

increases expression

4-nitrophenol results in increased expression of ITPR2 mRNA

NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164

G

kinesin family member 13B

increases expression

4-nitrophenol results in increased expression of KIF13B mRNA

NCBI chr15:38,908,257...39,066,021
Ensembl chr15:38,924,624...39,084,879

G

KLF transcription factor 2

decreases expression

4-nitrophenol results in decreased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KRAS proto-oncogene, GTPase

decreases expression

4-nitrophenol results in decreased expression of KRAS mRNA

NCBI chr 4:178,185,418...178,218,484

G

leucine-rich repeat-containing G protein-coupled receptor 6

increases expression

4-nitrophenol results in increased expression of LGR6 mRNA

NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945

G

lamin B1

decreases expression

4-nitrophenol results in decreased expression of LMNB1 mRNA

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

lamin B2

decreases expression

4-nitrophenol results in decreased expression of LMNB2 mRNA

NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665

G

mitogen-activated protein kinase kinase kinase 14

decreases expression

4-nitrophenol results in decreased expression of MAP3K14 mRNA

NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523

G

mitogen-activated protein kinase kinase kinase 5

decreases expression

4-nitrophenol results in decreased expression of MAP3K5 mRNA

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen-activated protein kinase 11

decreases expression

4-nitrophenol results in decreased expression of MAPK11 mRNA

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

G

mitogen activated protein kinase 13

decreases expression

4-nitrophenol results in decreased expression of MAPK13 mRNA

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

G

mitogen activated protein kinase 14

increases expression

4-nitrophenol results in increased expression of MAPK14 mRNA

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

methionine adenosyltransferase 2A

decreases expression

4-nitrophenol results in decreased expression of MAT2A mRNA

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

minichromosome maintenance complex component 3

decreases expression

4-nitrophenol results in decreased expression of MCM3 mRNA

NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314

G

minichromosome maintenance complex component 4

decreases expression

4-nitrophenol results in decreased expression of MCM4 mRNA

NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144

G

major facilitator superfamily domain containing 13B

increases expression

4-nitrophenol results in increased expression of MFSD13B mRNA

NCBI chr 1:175,528,077...175,560,263
Ensembl chr 1:175,527,930...175,560,136

G

modulator of VRAC current 1

decreases expression

4-nitrophenol results in decreased expression of MLC1 mRNA

NCBI chr 7:120,046,705...120,067,049
Ensembl chr 7:120,046,705...120,067,049

G

matrix metallopeptidase 12

increases expression

4-nitrophenol results in increased expression of MMP12 mRNA

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

G

nanos C2HC-type zinc finger 1

decreases expression

4-nitrophenol results in decreased expression of NANOS1 mRNA

NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730

G

neural cell adhesion molecule 1

decreases expression

4-nitrophenol results in decreased expression of NCAM1 mRNA

NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014

G

NFKB inhibitor alpha

decreases expression

4-nitrophenol results in decreased expression of NFKBIA mRNA

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nemo like kinase

decreases expression

4-nitrophenol results in decreased expression of NLK mRNA

NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730

G

NAD(P)H quinone dehydrogenase 1

increases expression

4-nitrophenol results in increased expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions

[NR1I3 protein affects the metabolism of Parathion] which affects the chemical synthesis of 4-nitrophenol

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

neurotrophic receptor tyrosine kinase 1

increases expression

4-nitrophenol results in increased expression of NTRK1 mRNA

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

outer dense fiber of sperm tails 2

increases expression

4-nitrophenol results in increased expression of ODF2 mRNA

NCBI chr 3:13,160,981...13,207,223
Ensembl chr 3:13,161,494...13,206,985

G

olfactory receptor family 5 subfamily AC member 16

increases expression

4-nitrophenol results in increased expression of OR5AC16 mRNA

G

origin recognition complex, subunit 1

decreases expression

4-nitrophenol results in decreased expression of ORC1 mRNA

NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375

G

origin recognition complex, subunit 2

decreases expression

4-nitrophenol results in decreased expression of ORC2 mRNA

NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195

G

origin recognition complex, subunit 3

increases expression

4-nitrophenol results in increased expression of ORC3 mRNA

NCBI chr 5:49,123,758...49,181,552
Ensembl chr 5:49,126,955...49,181,633

G

origin recognition complex, subunit 4

decreases expression

4-nitrophenol results in decreased expression of ORC4 mRNA

NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824

G

poly (ADP-ribose) polymerase family, member 16

affects expression

4-nitrophenol affects the expression of PARP16 mRNA

NCBI chr 8:65,731,152...65,749,438
Ensembl chr 8:65,727,706...65,749,433

G

p53-induced death domain protein 1

decreases expression

4-nitrophenol results in decreased expression of PIDD1 mRNA

NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

increases expression

4-nitrophenol results in increased expression of PIK3CD mRNA

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

G

phosphoinositide-3-kinase regulatory subunit 1

increases expression

4-nitrophenol results in increased expression of PIK3R1 mRNA

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

PTEN induced kinase 1

increases expression

4-nitrophenol results in increased expression of PINK1 mRNA

NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635

G

placenta enriched 1

decreases expression

4-nitrophenol results in decreased expression of PLAC1 mRNA

NCBI chr X:132,821,347...132,955,143
Ensembl chr X:132,821,347...132,985,668

G

polo-like kinase 3

decreases expression

4-nitrophenol results in decreased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

paraoxonase 1

increases chemical synthesis

PON1 protein results in increased chemical synthesis of 4-nitrophenol

NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

decreases expression

4-nitrophenol results in decreased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein kinase AMP-activated catalytic subunit alpha 1

decreases expression

4-nitrophenol results in decreased expression of PRKAA1 mRNA

NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978

G

protein kinase, DNA-activated, catalytic subunit

increases expression

4-nitrophenol results in increased expression of PRKDC mRNA

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

G

protein kinase cGMP-dependent 2

decreases expression

4-nitrophenol results in decreased expression of PRKG2 mRNA

NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888

G

prokineticin receptor 1

decreases expression

4-nitrophenol results in decreased expression of PROKR1 mRNA

NCBI chr 4:120,022,301...120,033,367
Ensembl chr 4:120,021,747...120,033,379

G

phosphatase and tensin homolog

decreases expression

4-nitrophenol results in decreased expression of PTEN mRNA

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

protein tyrosine phosphatase, non-receptor type 13

increases expression

4-nitrophenol results in increased expression of PTPN13 mRNA

NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563

G

protein tyrosine phosphatase, non-receptor type 7

decreases expression

4-nitrophenol results in decreased expression of PTPN7 mRNA

NCBI chr13:46,570,904...46,584,048
Ensembl chr13:46,571,712...46,583,308

G

RB transcriptional corepressor like 1

decreases expression

4-nitrophenol results in decreased expression of RBL1 mRNA

NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330

G

receptor interacting serine/threonine kinase 1

decreases expression

4-nitrophenol results in decreased expression of RIPK1 mRNA

NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824

G

ring finger protein 112

decreases expression

4-nitrophenol results in decreased expression of RNF112 mRNA

NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699

G

sphingosine-1-phosphate receptor 1

increases expression

4-nitrophenol results in increased expression of S1PR1 mRNA

NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681

G

sodium voltage-gated channel alpha subunit 1

increases expression

4-nitrophenol results in increased expression of SCN1A mRNA

NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699

G

selenium binding protein 1

increases expression

4-nitrophenol results in increased expression of SELENBP1 mRNA

NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594

G

septin 8

increases expression

4-nitrophenol results in increased expression of SEPTIN8 mRNA

NCBI chr10:37,684,649...37,713,704
Ensembl chr10:37,684,639...37,713,174

G

serpin family B member 7

decreases expression

4-nitrophenol results in decreased expression of SERPINB7 mRNA

NCBI chr13:23,369,830...23,442,205
Ensembl chr13:23,395,671...23,442,205

G

serpin family B member 8

increases expression

4-nitrophenol results in increased expression of SERPINB8 mRNA

NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835

G

serpin family E member 1

increases expression

4-nitrophenol results in increased expression of SERPINE1 mRNA

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

stratifin

decreases expression

4-nitrophenol results in decreased expression of SFN mRNA

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

serum/glucocorticoid regulated kinase family, member 3

increases expression

4-nitrophenol results in increased expression of SGK3 mRNA

NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476

G

sirtuin 1

decreases expression

4-nitrophenol results in decreased expression of SIRT1 mRNA

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

S-phase kinase associated protein 2

decreases expression

4-nitrophenol results in decreased expression of SKP2 mRNA

NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338

G

solute carrier family 39 member 4

decreases expression

4-nitrophenol results in decreased expression of SLC39A4 mRNA

NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553

G

secretory leukocyte peptidase inhibitor

decreases expression

4-nitrophenol results in decreased expression of SLPI mRNA

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

G

SMAD family member 2

decreases expression

4-nitrophenol results in decreased expression of SMAD2 mRNA

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

G

structural maintenance of chromosomes 1B

increases expression

4-nitrophenol results in increased expression of SMC1B mRNA

NCBI chr 7:116,180,987...116,242,778
Ensembl chr 7:116,180,987...116,242,744

G

small integral membrane protein 38

increases expression

4-nitrophenol results in increased expression of SMIM38 mRNA

NCBI chr 1:200,366,561...200,371,976

G

superoxide dismutase 2

decreases expression

4-nitrophenol results in decreased expression of SOD2 mRNA

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

SOS Ras/Rac guanine nucleotide exchange factor 1

decreases expression

4-nitrophenol results in decreased expression of SOS1 mRNA

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

G

sphingosine kinase 1

increases expression

4-nitrophenol results in increased expression of SPHK1 mRNA

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

serine and arginine rich splicing factor 1

decreases expression

4-nitrophenol results in decreased expression of SRSF1 mRNA

NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336

G

sulfiredoxin 1

increases expression

4-nitrophenol results in increased expression of SRXN1 mRNA

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

STAG1 cohesin complex component

decreases expression

4-nitrophenol results in decreased expression of STAG1 mRNA

NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677

G

signal transducer and activator of transcription 3

increases expression

4-nitrophenol results in increased expression of STAT3 mRNA

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

stanniocalcin 1

decreases expression

4-nitrophenol results in decreased expression of STC1 mRNA

NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264

G

STEAP3 metalloreductase

increases expression

4-nitrophenol results in increased expression of STEAP3 mRNA

NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519

G

sulfotransferase family 1A member 1

multiple interactions
increases metabolic processing
increases sulfation
affects sulfation

2,6-dichloro-4-nitrophenol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; 3,3'-diiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; 4-nitrophenol inhibits the reaction [SULT1A1 protein results in decreased sulfation of bisphenol A]; acetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Chlorophenols analog inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; daidzein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Ethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Genistein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Methanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Polychlorinated Biphenyls analog inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Sodium Chloride inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Thyroxine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Triiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]; Triiodothyronine, Reverse inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]
SULT1A1 protein results in increased metabolism of 4-nitrophenol
SULT1A1 gene polymorphism affects the sulfation of 4-nitrophenol

PMID:10623578 PMID:11181495 PMID:11425650 PMID:12206822 PMID:14570759 More...

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

sulfotransferase family 1B member 1

increases metabolic processing

SULT1B1 protein results in increased metabolism of 4-nitrophenol

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

G

sulfotransferase family 1C member 2A

increases sulfation

SULT1C2 protein results in increased sulfation of 4-nitrophenol; SULT1C2A protein results in increased sulfation of 4-nitrophenol

NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734

G

sulfotransferase family 1E member 1

increases sulfation

SULT1E1 protein results in increased sulfation of 4-nitrophenol

NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275

G

sulfotransferase family 2A member 1

increases metabolic processing

SULT2A1 protein results in increased metabolism of 4-nitrophenol

NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134

G

sulfotransferase family 4A, member 1

increases metabolic processing

SULT4A1 protein results in increased metabolism of 4-nitrophenol

NCBI chr 7:115,216,066...115,240,156
Ensembl chr 7:115,216,066...115,240,085

G

teneurin transmembrane protein 4

decreases expression

4-nitrophenol results in decreased expression of TENM4 mRNA

NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144

G

terminal nucleotidyltransferase 5C

increases expression

4-nitrophenol results in increased expression of TENT5C mRNA

NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744

G

transcription factor Dp-1

decreases expression

4-nitrophenol results in decreased expression of TFDP1 mRNA

NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817

G

transferrin receptor

decreases expression

4-nitrophenol results in decreased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta 2

increases expression

4-nitrophenol results in increased expression of TGFB2 mRNA

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

G

transforming growth factor, beta 3

increases expression

4-nitrophenol results in increased expression of TGFB3 mRNA

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

G

transforming growth factor, beta receptor 1

decreases expression

4-nitrophenol results in decreased expression of TGFBR1 mRNA

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

G

transforming growth factor, beta receptor 2

decreases expression

4-nitrophenol results in decreased expression of TGFBR2 mRNA

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

G

TLC domain containing 5

increases expression

4-nitrophenol results in increased expression of TLCD5 mRNA

NCBI chr 8:43,481,388...43,486,288
Ensembl chr 8:43,479,016...43,486,290

G

translation machinery associated 16 homolog

decreases expression

4-nitrophenol results in decreased expression of TMA16 mRNA

NCBI chr16:23,236,686...23,252,706
Ensembl chr16:23,236,710...23,252,701

G

thiol methyltransferase 1B

decreases expression

4-nitrophenol results in decreased expression of TMT1B mRNA

NCBI chr 7:1,388,876...1,391,526
Ensembl chr 7:1,388,879...1,391,526

G

tumor necrosis factor

decreases expression

4-nitrophenol results in decreased expression of TNF mRNA

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 10b

increases expression

4-nitrophenol results in increased expression of TNFRSF10B mRNA

NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467

G

TNF superfamily member 18

decreases expression

4-nitrophenol results in decreased expression of TNFSF18 mRNA

NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169

G

tenomodulin

decreases expression

4-nitrophenol results in decreased expression of TNMD mRNA

NCBI chr X:97,057,137...97,072,634
Ensembl chr X:97,057,137...97,072,634

G

tumor protein p53

affects glucuronidation

TP53 protein affects the glucuronidation of 4-nitrophenol

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p53 inducible nuclear protein 1

increases expression

4-nitrophenol results in increased expression of TRP53INP1 mRNA

NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968

G

TNF receptor-associated factor 1

decreases expression

4-nitrophenol results in decreased expression of TRAF1 mRNA

NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807

G

translocation associated membrane protein 2

increases expression

4-nitrophenol results in increased expression of TRAM2 mRNA

NCBI chr 9:23,419,204...23,498,745
Ensembl chr 9:23,424,232...23,498,689

G

tribbles pseudokinase 2

decreases expression

4-nitrophenol results in decreased expression of TRIB2 mRNA

NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370

G

TRIO and F-actin binding protein

decreases expression

4-nitrophenol results in decreased expression of TRIOBP mRNA

NCBI chr 7:110,505,916...110,569,301
Ensembl chr 7:110,506,248...110,562,474

G

tubulin, alpha 4A

decreases expression

4-nitrophenol results in decreased expression of TUBA4A mRNA

NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918

G

UDP glucuronosyltransferase family 1 member A1

increases glucuronidation

UGT1A1 protein results in increased glucuronidation of 4-nitrophenol

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases glucuronidation

UGT1A3 protein results in increased glucuronidation of 4-nitrophenol

NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A6

affects metabolic processing
affects glucuronidation
increases glucuronidation
increases metabolic processing

UGT1A6 gene polymorphism affects the metabolism of 4-nitrophenol
UGT1A6 gene polymorphism affects the glucuronidation of 4-nitrophenol; UGT1A6 gene SNP affects the glucuronidation of 4-nitrophenol
UGT1A6 protein results in increased glucuronidation of 4-nitrophenol
UGT1A6 protein results in increased metabolism of 4-nitrophenol

PMID:9429234 PMID:15284531 PMID:15761113 PMID:15802387 PMID:15921999

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase 1 family, polypeptide A7C

increases glucuronidation

UGT1A7 protein results in increased glucuronidation of 4-nitrophenol

NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A8

increases glucuronidation

UGT1A8 protein results in increased glucuronidation of 4-nitrophenol

NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A9

increases glucuronidation

UGT1A9 protein results in increased glucuronidation of 4-nitrophenol

PMID:15044611 PMID:15802387

NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 2 member B15

increases metabolic processing

UGT2B15 protein results in increased metabolism of 4-nitrophenol

NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589

G

ubiquitin specific peptidase 7

decreases expression

4-nitrophenol results in decreased expression of USP7 mRNA

NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355

G

vezatin, adherens junctions transmembrane protein

increases expression

4-nitrophenol results in increased expression of VEZT mRNA

NCBI chr 7:28,512,214...28,597,429
Ensembl chr 7:28,534,249...28,597,356

G

X-box binding protein 1

multiple interactions
increases expression

Quercetin inhibits the reaction [4-nitrophenol results in increased expression of XBP1 mRNA]

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

yippee-like 3

increases expression

4-nitrophenol results in increased expression of YPEL3 mRNA

NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

decreases expression

4-nitrophenol results in decreased expression of YWHAG mRNA

NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827

1,2-epoxy-3-(4-nitrophenoxy)propane

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutathione S-transferase theta 1

multiple interactions
affects metabolic processing
increases glutathionylation

GSTT1 gene SNP inhibits the reaction [GSTT1 protein results in increased glutathionylation of 1,2-epoxy-3-(p-nitrophenoxy)propane]
GSTT1 protein affects the metabolism of and results in decreased activity of 1,2-epoxy-3-(p-nitrophenoxy)propane; GSTT1 protein affects the metabolism of and results in decreased susceptibility to 1,2-epoxy-3-(p-nitrophenoxy)propane
GSTT1 protein affects the metabolism of 1,2-epoxy-3-(p-nitrophenoxy)propane

PMID:7578934 PMID:8951341 PMID:9854036 PMID:15683365 PMID:15882759 More...

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

4-nitrophenyl acetate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions
increases oxidation

[ALDH1A1 protein results in increased oxidation of 4-nitrophenyl acetate] results in increased chemical synthesis of [4-nitrophenol co-treated with Acetic Acid]

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

multiple interactions
increases hydrolysis

daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A1

increases hydrolysis

ALDH3A1 protein results in increased hydrolysis of 4-nitrophenyl acetate

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

aldehyde dehydrogenase 3 family, member B1

affects binding

4-nitrophenyl acetate binds to ALDH3B1 protein

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

carbonic anhydrase 2

increases metabolic processing

CA2 protein results in increased metabolism of 4-nitrophenyl acetate

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

G

carboxyl ester lipase

affects metabolic processing

CEL protein affects the metabolism of 4-nitrophenyl acetate

NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035

G

carboxylesterase 1D

multiple interactions
increases metabolic processing
decreases metabolic processing
increases hydrolysis

[CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate] which results in increased chemical synthesis of 4-nitrophenol; Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; CES1 protein binds to and results in increased hydrolysis of 4-nitrophenyl acetate; Fluoxetine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Thioridazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]
CES1 protein results in increased metabolism of 4-nitrophenyl acetate
CES1 gene mutant form results in decreased metabolism of 4-nitrophenyl acetate

PMID:10518925 PMID:16282638 PMID:18485328 PMID:20097249

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 2E

affects metabolic processing

CES2E protein affects the metabolism of 4-nitrophenyl acetate

NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856

G

carboxylesterase 3a

increases hydrolysis

CES3 protein results in increased hydrolysis of 4-nitrophenyl acetate

NCBI chr19:32,992,386...33,000,562

G

paraoxonase 1

increases hydrolysis

PON1 protein results in increased hydrolysis of 4-nitrophenyl acetate

NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360

4-nitrophenyl beta-D-glucuronide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 4

multiple interactions

4-nitrophenylglucuronide inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate]

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

4-nitrophenyl beta-D-xyloside

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

follicle stimulating hormone subunit beta

multiple interactions

4-nitrophenyl beta-D-xyloside inhibits the reaction [FSHB protein results in increased activity of PDE4A protein]

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

phosphodiesterase 4A

multiple interactions

4-nitrophenyl beta-D-xyloside inhibits the reaction [FSHB protein results in increased activity of PDE4A protein]

NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961

4-nitrophenyl hydrogen sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

steroid sulfatase

decreases activity

4-nitrophenyl sulfate results in decreased activity of STS protein

NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402

4-nitrophenyl phosphate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acid phosphatase 1

multiple interactions
increases hydrolysis

Benzoic Acid analog inhibits the reaction [ACP1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [ACP1 protein results in increased hydrolysis of nitrophenylphosphate]

NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021

G

alkaline phosphatase, placental

increases chemical synthesis

ALPP protein results in increased chemical synthesis of nitrophenylphosphate

NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606

G

dual specificity phosphatase 23

decreases phosphorylation
multiple interactions

DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate
Edetic Acid inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]; Ethylmaleimide inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]; Vanadates inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]

NCBI chr13:85,097,899...85,100,054
Ensembl chr13:85,097,899...85,100,093

G

phosphoglycolate phosphatase

decreases phosphorylation

PGP protein results in decreased phosphorylation of nitrophenylphosphate analog

NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858

G

protein tyrosine phosphatase, non-receptor type 1

multiple interactions
increases hydrolysis

Benzoic Acid analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate]

NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504

G

protein tyrosine phosphatase, non-receptor type 2

increases hydrolysis
multiple interactions

PTPN2 protein results in increased hydrolysis of nitrophenylphosphate
Benzoic Acid analog inhibits the reaction [PTPN2 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN2 protein results in increased hydrolysis of nitrophenylphosphate]

NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627

bis-4-nitrophenyl phosphate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase

multiple interactions

bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine]

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

ATP binding cassette subfamily B member 1A

multiple interactions

bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1A protein affects the metabolism of irinotecan]; bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1A protein affects the stability of Everolimus]

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP-binding cassette, sub-family B member 1B

multiple interactions

bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1B protein affects the metabolism of irinotecan]; bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1B protein affects the stability of Everolimus]

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily G member 2

multiple interactions

bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]; bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the stability of Everolimus]

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

albumin

multiple interactions

bis(4-nitrophenyl)phosphate inhibits the reaction [ALB protein results in increased hydrolysis of Carbaryl]; bis(4-nitrophenyl)phosphate inhibits the reaction [ALB protein results in increased hydrolysis of Methiocarb]

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

carboxylesterase 1D

decreases activity

bis(4-nitrophenyl)phosphate results in decreased activity of CES1 protein

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 2H

decreases activity

bis(4-nitrophenyl)phosphate results in decreased activity of CES2 protein

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

glutathione-disulfide reductase

multiple interactions

bis(4-nitrophenyl)phosphate inhibits the reaction [N-acetyl-S-pentachloro-1,3-butadienylcysteine results in decreased activity of GSR protein]

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

p-nitrophenyl butyrate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

carboxylesterase 1D

multiple interactions
increases hydrolysis

CES1 protein binds to and results in increased hydrolysis of 4-nitrophenyl butyrate
CES1 protein results in increased hydrolysis of 4-nitrophenyl butyrate

PMID:11950785 PMID:16282638

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 3a

increases hydrolysis

CES3 protein results in increased hydrolysis of 4-nitrophenyl butyrate

NCBI chr19:32,992,386...33,000,562

parathion

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha 1,4-galactosyltransferase

increases methylation

Parathion results in increased methylation of A4GALT promoter

NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071

G

aralkylamine N-acetyltransferase

increases expression
multiple interactions

Parathion results in increased expression of AANAT protein
Propranolol inhibits the reaction [Parathion results in increased expression of AANAT protein]

NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801

G

ATP binding cassette subfamily A member 1

increases methylation

Parathion results in increased methylation of ABCA1 promoter

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 5

increases methylation

Parathion results in increased methylation of ABCA5 promoter

NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976

G

ATP binding cassette subfamily A member 6

increases expression

Parathion results in increased expression of ABCA6 mRNA

NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530

G

ATP binding cassette subfamily B member 11

decreases expression

Parathion results in decreased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily B member 1A

affects binding
multiple interactions
decreases export

Parathion binds to ABCB1 protein
Parathion inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]
ABCB1 protein results in decreased export of Parathion

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

increases expression

Parathion results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

Parathion results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily D member 2

increases expression

Parathion results in increased expression of ABCD2 mRNA

NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642

G

abhydrolase domain containing 1

decreases expression

Parathion results in decreased expression of ABHD1 mRNA

NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514

G

abhydrolase domain containing 12B

increases methylation

Parathion results in increased methylation of ABHD12B promoter

NCBI chr 6:88,668,627...88,696,435
Ensembl chr 6:88,668,642...88,696,458

G

abhydrolase domain containing 2, acylglycerol lipase

increases expression

Parathion results in increased expression of ABHD2 mRNA

NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

multiple interactions
increases expression

[Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA
Parathion results in increased expression of ABL1 mRNA

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

G

acetyl-CoA carboxylase beta

decreases expression

Parathion results in decreased expression of ACACB mRNA

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

acyl-CoA dehydrogenase family, member 10

increases expression

Parathion results in increased expression of ACAD10 mRNA

NCBI chr12:34,901,211...34,943,973
Ensembl chr12:34,901,219...34,982,521

G

acyl-CoA dehydrogenase medium chain

increases expression

Parathion results in increased expression of ACADM mRNA

NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147

G

acetylcholinesterase

multiple interactions
decreases activity
increases expression
decreases expression

[Methyl Parathion co-treated with Parathion] results in decreased activity of ACHE protein; [Parathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; Parathion results in decreased expression of and results in decreased activity of ACHE protein
Parathion results in decreased activity of ACHE protein
Parathion results in increased expression of ACHE mRNA alternative form
Parathion results in decreased expression of ACHE mRNA
Parathion metabolite results in decreased activity of ACHE protein; Parathion results in decreased activity of ACHE protein

PMID:1512808 PMID:4859365 PMID:7150809 PMID:15342957 PMID:17707571 More...

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

aconitase 2

increases expression

Parathion results in increased expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA thioesterase 11

increases methylation

Parathion results in increased methylation of ACOT11 promoter

NCBI chr 5:121,523,833...121,581,699
Ensembl chr 5:121,527,435...121,581,538

G

acyl-CoA thioesterase 3

increases expression

Parathion results in increased expression of ACOT3 mRNA

NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427

G

acyl-CoA thioesterase 4

increases expression

Parathion results in increased expression of ACOT4 mRNA

NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917

G

actin-like 9

increases methylation

Parathion results in increased methylation of ACTL9 promoter

NCBI chr 7:14,234,504...14,235,881
Ensembl chr 7:14,234,504...14,235,881

G

activin A receptor type 1C

increases methylation

Parathion results in increased methylation of ACVR1C promoter

NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327

G

ADAM metallopeptidase domain 23

increases methylation

Parathion results in increased methylation of ADAM23 promoter

NCBI chr 9:64,862,649...65,009,718
Ensembl chr 9:64,862,878...65,006,515

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

increases methylation

Parathion results in increased methylation of ADAMTS1 promoter

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

increases methylation

Parathion results in increased methylation of ADAMTS5 promoter

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

increases expression

Parathion results in increased expression of ADAMTS7 mRNA

NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328

G

ADAMTS-like 4

increases expression

Parathion results in increased expression of ADAMTSL4 mRNA

NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848

G

adenylate cyclase 2

increases methylation

Parathion results in increased methylation of ADCY2 promoter

NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236

G

adenylate cyclase 8

increases methylation

Parathion results in increased methylation of ADCY8 promoter

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

G

adducin 3

increases expression

Parathion results in increased expression of ADD3 mRNA

NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124

G

adhesion G protein-coupled receptor L2

increases methylation

Parathion results in increased methylation of ADGRL2 promoter

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

adrenoceptor beta 2

increases methylation

Parathion results in increased methylation of ADRB2 promoter

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

actin filament associated protein 1

increases methylation

Parathion results in increased methylation of AFAP1 promoter

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

ALF transcription elongation factor 2

increases methylation

Parathion results in increased methylation of AFF2 promoter

NCBI chr X:147,928,130...148,432,484
Ensembl chr X:147,928,407...148,429,995

G

ALF transcription elongation factor 4

decreases expression

Parathion results in decreased expression of AFF4 mRNA

NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751

G

aspartylglucosaminidase

decreases methylation

Parathion results in decreased methylation of AGA promoter

NCBI chr16:38,504,661...38,516,607
Ensembl chr16:38,504,663...38,516,606

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

decreases methylation

Parathion results in decreased methylation of AGAP1 promoter

NCBI chr 9:90,039,720...90,475,196
Ensembl chr 9:90,039,605...90,470,958

G

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

increases expression

Parathion results in increased expression of AGL mRNA

NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828

G

argonaute RISC component 4

decreases methylation

Parathion results in decreased methylation of AGO4 promoter

NCBI chr 5:138,780,446...138,825,898
Ensembl chr 5:138,783,069...138,825,632

G

1-acylglycerol-3-phosphate O-acyltransferase 2

decreases expression

Parathion results in decreased expression of AGPAT2 mRNA

NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371

G

angiotensinogen

increases expression

Parathion results in increased expression of AGT mRNA

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

adenosylhomocysteinase

increases expression

Parathion results in increased expression of AHCY mRNA

NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393

G

aryl hydrocarbon receptor

increases activity

Parathion results in increased activity of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aryl-hydrocarbon receptor repressor

increases methylation

Parathion results in increased methylation of AHRR promoter

NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

Parathion results in increased expression of AIMP1 mRNA

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

adenylate kinase 5

increases methylation

Parathion results in increased methylation of AK5 promoter

NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458

G

aldo-keto reductase family 1 member B1

increases methylation

Parathion results in increased methylation of AKR1B1 promoter

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

5'-aminolevulinate synthase 2

decreases expression

Parathion results in decreased expression of ALAS2 mRNA

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

albumin

affects binding

Parathion binds to ALB protein

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

activated leukocyte cell adhesion molecule

increases methylation

Parathion results in increased methylation of ALCAM promoter

NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954

G

aldehyde dehydrogenase 1 family, member A3

increases methylation

Parathion results in increased methylation of ALDH1A3 promoter

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

ALK receptor tyrosine kinase

increases methylation

Parathion results in increased methylation of ALK promoter

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

G

ALK and LTK ligand 1

increases methylation

Parathion results in increased methylation of ALKAL1 promoter

NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948

G

alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase

increases methylation

Parathion results in increased methylation of ALKBH3 promoter

NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000

G

arachidonate 5-lipoxygenase activating protein

decreases expression

Parathion results in decreased expression of ALOX5AP mRNA

NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986

G

ALX homeobox 3

increases methylation

Parathion results in increased methylation of ALX3 promoter

NCBI chr 2:195,231,197...195,241,609
Ensembl chr 2:195,231,197...195,241,609

G

ALX homeobox 4

increases methylation

Parathion results in increased methylation of ALX4 promoter

NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260

G

amphiphysin

increases methylation

Parathion results in increased methylation of AMPH promoter

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

G

angiopoietin-like 4

increases expression

Parathion results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin repeat domain 29

increases methylation

Parathion results in increased methylation of ANKRD29 promoter

NCBI chr18:3,436,301...3,494,292
Ensembl chr18:3,436,303...3,494,296

G

ankyrin repeat domain 7

increases methylation

Parathion results in increased methylation of ANKRD7 promoter

NCBI chr 4:47,312,270...47,336,754
Ensembl chr 4:47,318,420...47,336,753

G

ANTXR cell adhesion molecule 1

increases methylation

Parathion results in increased methylation of ANTXR1 promoter

NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232

G

adaptor related protein complex 2 subunit mu 1

increases expression

Parathion results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

adaptor related protein complex 3 subunit beta 1

decreases methylation

Parathion results in decreased methylation of AP3B1 promoter

NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935

G

APC down-regulated 1 like

increases methylation

Parathion results in increased methylation of APCDD1L promoter

NCBI chr 3:162,587,484...162,658,362
Ensembl chr 3:162,582,252...162,658,073

G

apolipoprotein A1

increases methylation

Parathion results in increased methylation of APOA1 promoter

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

amyloid beta precursor protein

increases methylation

Parathion results in increased methylation of APP promoter

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

decreases expression

Parathion results in decreased expression of APPL1 mRNA

NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692

G

aquaporin 8

decreases expression

Parathion results in decreased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

androgen receptor

multiple interactions
affects binding

Dihydrotestosterone inhibits the reaction [Parathion results in increased activity of AR protein]; Parathion inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
Parathion binds to AR protein

PMID:14565775 PMID:15064155 PMID:17980950

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

increases methylation
increases expression

Parathion results in increased methylation of ARAP2 promoter
Parathion results in increased expression of ARAP2 mRNA

PMID:22847954 PMID:34813904

NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

decreases methylation

Parathion results in decreased methylation of ARAP3 promoter

NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555

G

Rho GTPase activating protein 29

increases methylation

Parathion results in increased methylation of ARHGAP29 promoter

NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028

G

Rho guanine nucleotide exchange factor 16

increases methylation

Parathion results in increased methylation of ARHGEF16 promoter

NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212

G

ADP ribosylation factor like GTPase 4C

increases methylation

Parathion results in increased methylation of ARL4C promoter

NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513

G

ADP-ribosylation factor like GTPase 6 interacting protein 5

decreases expression

Parathion results in decreased expression of ARL6IP5 mRNA

NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608

G

armadillo repeat containing, X-linked 2

increases methylation

Parathion results in increased methylation of ARMCX2 promoter

NCBI chr X:97,980,662...97,985,523
Ensembl chr X:97,980,660...97,985,552

G

actin related protein 2/3 complex, subunit 2

decreases methylation

Parathion results in decreased methylation of ARPC2 promoter

NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471

G

arrestin domain containing 4

increases expression

Parathion results in increased expression of ARRDC4 mRNA

NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290

G

argininosuccinate lyase

increases expression

Parathion results in increased expression of ASL mRNA

NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662

G

aspartate-beta-hydroxylase

increases methylation

Parathion results in increased methylation of ASPH promoter

NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876

G

astrotactin 2

increases methylation

Parathion results in increased methylation of ASTN2 promoter

NCBI chr 5:78,758,142...79,744,021
Ensembl chr 5:78,758,142...79,748,273

G

ankyrin repeat, SAM and basic leucine zipper domain containing 1

increases methylation

Parathion results in increased methylation of ASZ1 promoter

NCBI chr 4:46,400,485...46,456,085
Ensembl chr 4:46,400,485...46,456,085

G

ATPase family, AAA domain containing 2B

decreases expression

Parathion results in decreased expression of ATAD2B mRNA

NCBI chr 6:27,914,546...28,070,103
Ensembl chr 6:27,912,862...28,067,047

G

ATPase phospholipid transporting 10A (putative)

increases methylation

Parathion results in increased methylation of ATP10A promoter

NCBI chr 1:109,556,760...109,730,440
Ensembl chr 1:109,556,782...109,730,437

G

ATPase Na+/K+ transporting subunit alpha 4

increases methylation

Parathion results in increased methylation of ATP1A4 promoter

NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687

G

ATP synthase F1 subunit gamma

increases expression

Parathion results in increased expression of ATP5F1C mRNA

NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367

G

ATPase, H+ transporting V0 subunit e2

decreases expression

Parathion results in decreased expression of ATP6V0E2 mRNA

NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777

G

ATPase phospholipid transporting 8B1

decreases expression

Parathion results in decreased expression of ATP8B1 mRNA

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

attractin like 1

increases methylation

Parathion results in increased methylation of ATRNL1 promoter

NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197

G

ATRX, chromatin remodeler

increases methylation

Parathion results in increased methylation of ATRX promoter

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

ataxin 1

increases methylation

Parathion results in increased methylation of ATXN1 promoter

NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360

G

beta-1,4-N-acetyl-galactosaminyl transferase 2

increases methylation

Parathion results in increased methylation of B4GALNT2 promoter

NCBI chr10:80,801,594...80,828,005
Ensembl chr10:80,802,941...80,857,700

G

beta-secretase 2

increases methylation

Parathion results in increased methylation of BACE2 promoter

NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546

G

BCL2-antagonist/killer 1

increases methylation

Parathion results in increased methylation of BAK1 promoter

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

B-cell scaffold protein with ankyrin repeats 1

increases methylation

Parathion results in increased methylation of BANK1 promoter

NCBI chr 2:224,530,475...224,800,420
Ensembl chr 2:224,530,475...224,800,405

G

Btg3 associated nuclear protein

increases methylation

Parathion results in increased methylation of BANP promoter

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

BarH-like homeobox 1

increases methylation

Parathion results in increased methylation of BARHL1 promoter

NCBI chr 3:12,241,327...12,248,649
Ensembl chr 3:12,241,327...12,248,649

G

butyrylcholinesterase

multiple interactions
decreases activity

[Methyl Parathion co-treated with Parathion] results in decreased activity of BCHE protein
Parathion results in decreased activity of BCHE protein

PMID:1512808 PMID:4998912 PMID:7150809 PMID:18617161 PMID:21767560 More...

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

decreases expression

Parathion results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression

Parathion results in decreased expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

bradykinin receptor B2

increases methylation

Parathion results in increased methylation of BDKRB2 promoter

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

G

BEN domain containing 5

increases methylation

Parathion results in increased methylation of BEND5 promoter

NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367

G

BEN domain containing 7

increases methylation

Parathion results in increased methylation of BEND7 promoter

NCBI chr17:73,483,212...73,566,221
Ensembl chr17:73,485,282...73,567,559

G

brain expressed X-linked 1

increases methylation

Parathion results in increased methylation of BEX2 promoter

NCBI chr X:99,219,014...99,220,518
Ensembl chr X:99,219,014...99,220,958

G

BICD family like cargo adaptor 1

increases methylation

Parathion results in increased methylation of BICDL1 promoter

NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130

G

BCL2-interacting killer

increases methylation

Parathion results in increased methylation of BIK promoter

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

BLCAP, apoptosis inducing factor

decreases expression

Parathion results in decreased expression of BLCAP mRNA

NCBI chr 3:146,222,699...146,232,859
Ensembl chr 3:146,222,240...146,232,909

G

bMERB domain containing 1

increases methylation

Parathion results in increased methylation of BMERB1 promoter

NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575

G

BMP-binding endothelial regulator

increases methylation

Parathion results in increased methylation of BMPER promoter

NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256

G

BPI fold containing family B, member 6

increases methylation

Parathion results in increased methylation of BPIFB6 promoter

NCBI chr 3:142,381,478...142,395,304
Ensembl chr 3:142,381,374...142,395,308

G

BSCL2 lipid droplet biogenesis associated, seipin

increases methylation

Parathion results in increased methylation of BSCL2 promoter

NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421

G

BTG anti-proliferation factor 4

increases methylation

Parathion results in increased methylation of BTG4 promoter

NCBI chr 8:51,410,774...51,425,802
Ensembl chr 8:51,422,061...51,425,796

G

similar to human chromosome 4 open reading frame 19

increases methylation

Parathion results in increased methylation of C4ORF19 promoter

NCBI chr14:44,387,386...44,478,344
Ensembl chr14:44,387,393...44,478,041

G

core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1

increases expression

Parathion results in increased expression of C1GALT1 mRNA

NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831

G

similar to human chromosome 3 open reading frame 22

increases methylation

Parathion results in increased methylation of C3ORF22 promoter

NCBI chr 4:122,817,681...122,822,175
Ensembl chr 4:122,817,681...122,822,175

G

complement C6

decreases expression

Parathion results in decreased expression of C6 mRNA

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

G

complement C8 beta chain

decreases expression

Parathion results in decreased expression of C8B mRNA

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

G

complement C9

decreases expression

Parathion results in decreased expression of C9 mRNA

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

G

calcium binding tyrosine phosphorylation regulated

increases methylation

Parathion results in increased methylation of CABYR promoter

NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840

G

cell adhesion molecule 1

increases expression

Parathion results in increased expression of CADM1 mRNA

NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833

G

cell adhesion molecule 3

increases methylation

Parathion results in increased methylation of CADM3 promoter

NCBI chr13:85,784,785...85,817,412
Ensembl chr13:85,786,483...85,817,749

G

calneuron 1

increases methylation

Parathion results in increased methylation of CALN1 promoter

NCBI chr12:25,811,743...26,303,670
Ensembl chr12:25,819,628...26,303,344

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

decreases expression

Parathion results in decreased expression of CAMK2N1 mRNA

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

G

calmodulin binding transcription activator 2

increases methylation

Parathion results in increased methylation of CAMTA2 promoter

NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558

G

cell cycle associated protein 1

decreases expression

Parathion results in decreased expression of CAPRIN1 mRNA

NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502

G

carbonic anhydrase 11

decreases methylation

Parathion results in decreased methylation of CA11 promoter

NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191

G

carbonic anhydrase 3

increases methylation

Parathion results in increased methylation of CA3 promoter

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

CART prepropeptide

increases methylation

Parathion results in increased methylation of CARTPT promoter

NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713

G

caspase 3

multiple interactions
increases cleavage
increases activity

acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Parathion results in increased activity of CASP3 protein]; acetyl-isoleucyl-glutamyl-threonyl-aspartyl-aldehyde inhibits the reaction [Parathion results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Parathion results in increased activity of CASP3 protein]
Parathion results in increased cleavage of CASP3 protein

PMID:11032765 PMID:36058312

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cation channel, sperm associated 2

increases expression

Parathion results in increased expression of CATSPER2 mRNA

NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050

G

caveolae associated protein 3

increases methylation

Parathion results in increased methylation of CAVIN3 promoter

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

carbonyl reductase 1

increases expression

Parathion results in increased expression of CBR1 mRNA

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

coiled-coil domain containing 112

decreases methylation

Parathion results in decreased methylation of CCDC112 promoter

NCBI chr18:38,998,139...39,032,329
Ensembl chr18:38,998,139...39,032,329

G

coiled-coil domain containing 38

increases methylation

Parathion results in increased methylation of CCDC38 promoter

NCBI chr 7:28,055,883...28,129,938
Ensembl chr 7:28,059,798...28,130,441

G

cholecystokinin

increases expression

Parathion results in increased expression of CCK mRNA

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 27

decreases methylation

Parathion results in decreased methylation of CCL27 promoter

NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506

G

C-C motif chemokine ligand 3

increases expression

Parathion results in increased expression of CCL3 protein

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

cellular communication network factor 2

increases methylation

Parathion results in increased methylation of CCN2 promoter

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 5

increases methylation

Parathion results in increased methylation of CCN5 promoter

NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636

G

cellular communication network factor 6

increases methylation

Parathion results in increased methylation of CCN6 promoter

NCBI chr20:42,569,309...42,585,126
Ensembl chr20:42,569,309...42,585,126

G

cyclin A1

multiple interactions
increases expression

[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
Parathion results in increased expression of CCNA1 mRNA

NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157

G

cyclin A2

multiple interactions
decreases expression

[Estradiol co-treated with Parathion] results in decreased expression of CCNA2 mRNA
Parathion results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin C

increases expression

Parathion results in increased expression of CCNC mRNA

NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584

G

cyclin D3

multiple interactions
increases expression

[Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA
Parathion results in increased expression of CCND3 mRNA

PMID:17390078 PMID:17622325

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

increases expression
multiple interactions

Parathion results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

multiple interactions
increases expression

[Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Parathion results in increased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

cyclin O

increases methylation

Parathion results in increased methylation of CCNO promoter

NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914

G

C-C motif chemokine receptor 8

increases methylation

Parathion results in increased methylation of CCR8 promoter

NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629

G

copper chaperone for superoxide dismutase

increases expression

Parathion results in increased expression of CCS mRNA

NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915

G

CD151 molecule (Raph blood group)

decreases expression

Parathion results in decreased expression of CD151 mRNA

NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753

G

CD22 molecule

decreases methylation

Parathion results in decreased methylation of CD22 promoter

NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322

G

CD226 molecule

increases methylation

Parathion results in increased methylation of CD226 promoter

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

G

CD302 molecule

increases methylation

Parathion results in increased methylation of CD302 promoter

NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045

G

CD38 molecule

increases methylation

Parathion results in increased methylation of CD38 promoter

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

G

CD3 delta subunit of T-cell receptor complex

increases expression

Parathion results in increased expression of CD3D mRNA

NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809

G

Cd47 molecule

decreases methylation

Parathion results in decreased methylation of CD47 promoter

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

G

Cd48 molecule

increases methylation

Parathion results in increased methylation of CD48 promoter

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

Cd53 molecule

decreases methylation

Parathion results in decreased methylation of CD53 promoter

NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657

G

Cd70 molecule

increases methylation

Parathion results in increased methylation of CD70 promoter

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

G

Cd72 molecule

increases methylation

Parathion results in increased methylation of CD72 promoter

NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725

G

CD8 subunit alpha

increases methylation

Parathion results in increased methylation of CD8A promoter

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

G

cell division cycle 20

multiple interactions
increases expression

[Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Parathion results in increased expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

CDC42 binding protein kinase alpha

decreases methylation

Parathion results in decreased methylation of CDC42BPA promoter

NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732

G

CDC42 effector protein 5

increases methylation

Parathion results in increased methylation of CDC42EP5 promoter

NCBI chr 1:70,035,921...70,038,990

G

cell division cycle 5-like

increases expression

Parathion results in increased expression of CDC5L mRNA

NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450

G

cell division cycle 6

increases expression
multiple interactions

Parathion results in increased expression of CDC6 mRNA
[Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA

PMID:17390078 PMID:17622325

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cadherin 8

increases methylation

Parathion results in increased methylation of CDH8 promoter

NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669

G

cadherin-related family member 1

increases methylation

Parathion results in increased methylation of CDHR1 promoter

NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396

G

cyclin-dependent kinase 1

multiple interactions
increases expression

[Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Parathion results in increased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 10

increases methylation

Parathion results in increased methylation of CDK10 promoter

NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078

G

cyclin-dependent kinase inhibitor 1A

increases expression

Parathion results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2A

increases expression

Parathion results in increased expression of CDKN2A mRNA

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2C

decreases expression

Parathion results in decreased expression of CDKN2C mRNA

NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278

G

cysteine dioxygenase type 1

increases expression

Parathion results in increased expression of CDO1 mRNA

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

carnitine deficiency-associated gene expressed in ventricle 3

increases expression

Parathion results in increased expression of CDV3 mRNA

NCBI chr 8:103,934,006...103,947,173
Ensembl chr 8:103,933,996...103,947,192

G

centromere protein A

decreases expression

Parathion results in decreased expression of CENPA mRNA

NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675

G

centrosomal protein 152

increases expression

Parathion results in increased expression of CEP152 mRNA

NCBI chr 3:112,803,185...112,878,298
Ensembl chr 3:112,810,425...112,878,458
Ensembl chr 3:112,810,425...112,878,458

G

carboxylesterase 2C

decreases expression

Parathion results in decreased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790

G

cilia and flagella associated protein 46

increases methylation

Parathion results in increased methylation of CFAP46 promoter

NCBI chr 1:194,403,212...194,482,790
Ensembl chr 1:194,403,211...194,482,730

G

cilia and flagella associated protein 65

increases methylation

Parathion results in increased methylation of CFAP65 promoter

NCBI chr 9:76,459,211...76,494,199
Ensembl chr 9:76,459,211...76,494,128

G

complement factor B

increases methylation

Parathion results in increased methylation of CFB promoter

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

G

chondroadherin

increases methylation

Parathion results in increased methylation of CHAD promoter

NCBI chr10:79,512,170...79,515,941
Ensembl chr10:79,511,931...79,515,940

G

choline O-acetyltransferase

multiple interactions
decreases expression
affects expression

Dietary Fats affects the reaction [Parathion affects the expression of CHAT protein]
Parathion results in decreased expression of CHAT protein

PMID:18941570 PMID:19590683 PMID:20015457

NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093

G

choline kinase alpha

decreases expression

Parathion results in decreased expression of CHKA mRNA

NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516

G

calcineurin-like EF-hand protein 1

increases expression

Parathion results in increased expression of CHP1 mRNA

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

G

cholinergic receptor, muscarinic 2

affects binding

Parathion binds to CHRM2 protein

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

cholinergic receptor nicotinic alpha 3 subunit

increases methylation

Parathion results in increased methylation of CHRNA3 promoter

NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165

G

carbohydrate sulfotransferase 5

increases expression
multiple interactions

Parathion results in increased expression of CHST6 mRNA
[Parathion co-treated with Estradiol] results in increased expression of CHST6 mRNA

NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064

G

carbohydrate sulfotransferase 7

increases expression
multiple interactions

Parathion results in increased expression of CHST7 mRNA
[Parathion co-treated with Estradiol] results in increased expression of CHST7 mRNA

NCBI chr X:2,396,260...2,432,828
Ensembl chr X:2,393,874...2,432,840

G

calcium and integrin binding 1

decreases expression

Parathion results in decreased expression of CIB1 mRNA

NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423

G

ciliary microtubule associated protein 2

increases methylation

Parathion results in increased methylation of CIMAP2 promoter

NCBI chr 5:121,375,998...121,401,869
Ensembl chr 5:121,375,998...121,401,869

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

increases methylation

Parathion results in increased methylation of CITED4 promoter

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

creatine kinase, mitochondrial 2

increases methylation

Parathion results in increased methylation of CKMT2 promoter

NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430

G

CDC28 protein kinase regulatory subunit 1B

decreases expression

Parathion results in decreased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

chloride channel accessory 2

increases methylation

Parathion results in increased methylation of CLCA2 promoter

NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199

G

chloride voltage-gated channel 4

decreases methylation

Parathion results in decreased methylation of CLCN4 promoter

NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238

G

claudin 1

increases methylation

Parathion results in increased methylation of CLDN1 promoter

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 19

increases methylation

Parathion results in increased methylation of CLDN19 promoter

NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227

G

claudin 6

increases methylation

Parathion results in increased methylation of CLDN6 promoter

NCBI chr10:12,710,302...12,713,987
Ensembl chr10:12,709,960...12,715,973

G

C-type lectin domain containing 14A

increases methylation

Parathion results in increased methylation of CLEC14A promoter

NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612

G

C-type lectin domain family 4, member A3

increases methylation

Parathion results in increased methylation of CLEC4A promoter

NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817

G

chloride intracellular channel 1

decreases methylation

Parathion results in decreased methylation of CLIC1 promoter

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

chloride intracellular channel 6

increases methylation

Parathion results in increased methylation of CLIC6 promoter

NCBI chr11:31,737,813...31,780,360
Ensembl chr11:31,737,813...31,780,061

G

clock circadian regulator

decreases expression

Parathion results in decreased expression of CLOCK mRNA

NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

decreases expression

Parathion results in decreased expression of CLPX mRNA

NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082

G

calsyntenin 2

increases methylation

Parathion results in increased methylation of CLSTN2 promoter

NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731

G

CKLF-like MARVEL transmembrane domain containing 6

decreases expression

Parathion results in decreased expression of CMTM6 mRNA

NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033

G

CTD nuclear envelope phosphatase 1 regulatory subunit 1

decreases expression

Parathion results in decreased expression of CNEP1R1 mRNA

NCBI chr19:18,932,631...18,947,667
Ensembl chr19:18,932,682...18,947,667

G

contactin associated protein 2

increases methylation

Parathion results in increased methylation of CNTNAP2 promoter

NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027

G

cytochrome C oxidase assembly factor 3

increases expression

Parathion results in increased expression of COA3 mRNA

NCBI chr10:86,220,192...86,221,173
Ensembl chr10:86,220,194...86,221,178

G

collagen type XIV alpha 1 chain

increases methylation

Parathion results in increased methylation of COL14A1 promoter

NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214

G

collagen type XV alpha 1 chain

decreases expression

Parathion results in decreased expression of COL15A1 mRNA

NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591

G

collagen type I alpha 1 chain

increases methylation

Parathion results in increased methylation of COL1A1 promoter

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type IV alpha 3 chain

increases methylation

Parathion results in increased methylation of COL4A3 promoter

NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895

G

collagen type VI alpha 3 chain

increases methylation

Parathion results in increased methylation of COL6A3 promoter

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

catechol-O-methyltransferase

decreases expression

Parathion results in decreased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

corin, serine peptidase

increases expression

Parathion results in increased expression of CORIN mRNA

NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503

G

carboxypeptidase E

increases methylation

Parathion results in increased methylation of CPE promoter

NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233

G

cellular retinoic acid binding protein 1

increases methylation

Parathion results in increased methylation of CRABP1 promoter

NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360

G

cellular repressor of E1A-stimulated genes 1

increases expression

Parathion results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich secretory protein LCCL domain containing 1

increases methylation

Parathion results in increased methylation of CRISPLD1 promoter

NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926

G

cardiolipin synthase 1

increases expression

Parathion results in increased expression of CRLS1 mRNA

NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655

G

collapsin response mediator protein 1

increases methylation

Parathion results in increased methylation of CRMP1 promoter

NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177

G

CREB regulated transcription coactivator 3

decreases expression

Parathion results in decreased expression of CRTC3 mRNA

NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500

G

crystallin beta-gamma domain containing 1

increases methylation

Parathion results in increased methylation of CRYBG1 promoter

NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392

G

crystallin, mu

increases expression

Parathion results in increased expression of CRYM mRNA

NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633

G

crystallin zeta

increases expression

Parathion results in increased expression of CRYZ mRNA

NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758

G

cysteine sulfinic acid decarboxylase

increases expression

Parathion results in increased expression of CSAD mRNA

NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615

G

colony stimulating factor 2

increases expression

Parathion results in increased expression of CSF2 protein

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 2 receptor subunit beta

increases methylation

Parathion results in increased methylation of CSF2RB promoter

NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157

G

catenin beta 1

multiple interactions
increases expression

Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein]
Parathion results in increased expression of CTNNB1 mRNA

PMID:17390078 PMID:34813904

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

catenin delta 2

increases methylation

Parathion results in increased methylation of CTNND2 promoter

NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764

G

cutC copper transporter

increases expression

Parathion results in increased expression of CUTC mRNA

NCBI chr 1:242,622,281...242,637,048
Ensembl chr 1:242,622,276...242,637,047

G

C-X-C motif chemokine ligand 14

increases methylation

Parathion results in increased methylation of CXCL14 promoter

NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

Parathion results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions

Parathion results in increased expression of CYP1A1 mRNA
3'-methoxy-4'-nitroflavone inhibits the reaction [Parathion results in increased expression of CYP1A1 mRNA]

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

affects metabolic processing
increases expression

CYP1A2 protein affects the metabolism of Parathion
Parathion results in increased expression of CYP1A2 mRNA

PMID:12669189 PMID:15557345 PMID:17079358 PMID:26196221

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 26, subfamily a, polypeptide 1

increases methylation

Parathion results in increased methylation of CYP26A1 promoter

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 2, subfamily a, polypeptide 3

increases expression

Parathion results in increased expression of CYP2A4 mRNA

NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979

G

cytochrome P450, family 2, subfamily b, polypeptide 1

affects metabolic processing
multiple interactions

CYP2B1 protein affects the metabolism of Parathion
Parathion inhibits the reaction [Phenobarbital results in increased activity of CYP2B1 protein]

PMID:15690761 PMID:16326433

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 3

affects metabolic processing
increases expression
decreases sulfation

CYP2B6 protein affects the metabolism of Parathion
Parathion results in increased expression of CYP2B6 mRNA
CYP2B6 protein results in decreased sulfation of Parathion

PMID:15557345 PMID:17079358 PMID:26196221

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily C, polypeptide 6

affects metabolic processing
increases expression

CYP2C19 protein affects the metabolism of Parathion
Parathion results in increased expression of CYP2C29 mRNA

PMID:12669189 PMID:17079358 PMID:34813904

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily c, polypeptide 79

affects metabolic processing

CYP2C8 protein affects the metabolism of Parathion

G

cytochrome P450, family 2, subfamily d, polypeptide 4

affects metabolic processing
increases expression

CYP2D6 protein affects the metabolism of Parathion
Parathion results in increased expression of CYP2D22 mRNA

PMID:12669189 PMID:34813904

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

affects metabolic processing
increases expression

CYP2E1 protein affects the metabolism of Parathion
Parathion results in increased expression of CYP2E1 mRNA

PMID:12669189 PMID:34813904

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily f, polypeptide 4

increases expression
multiple interactions

Parathion results in increased expression of CYP2F1 mRNA
[Parathion co-treated with Estradiol] results in increased expression of CYP2F1 mRNA

NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896

G

cytochrome P450, family 2, subfamily w, polypeptide 1

increases methylation

Parathion results in increased methylation of CYP2W1 promoter

NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421

G

cytochrome P450, family 3, subfamily a, polypeptide 2

affects metabolic processing
increases expression

CYP3A4 protein affects the metabolism of Parathion
Parathion results in increased expression of CYP3A4 mRNA; Parathion results in increased expression of CYP3A4 protein

PMID:12669189 PMID:17079358 PMID:17110060 PMID:26196221

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

affects metabolic processing

CYP3A5 protein affects the metabolism of Parathion

PMID:12669189 PMID:17079358 PMID:17110060

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 4, subfamily f, polypeptide 18

multiple interactions
increases expression

[Parathion co-treated with Estradiol] results in increased expression of CYP4F3 mRNA
Parathion results in increased expression of CYP4F3 mRNA

NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940

G

cytochrome P450 family 7 subfamily A member 1

increases expression

Parathion results in increased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytokine like 1

increases methylation

Parathion results in increased methylation of CYTL1 promoter

NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886

G

DAB adaptor protein 1

increases methylation

Parathion results in increased methylation of DAB1 promoter

NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552

G

deleted in azoospermia-like

increases methylation

Parathion results in increased methylation of DAZL promoter

NCBI chr 9:10,695,593...10,712,330
Ensembl chr 9:10,695,592...10,712,323

G

D-box binding PAR bZIP transcription factor

increases expression

Parathion results in increased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

DDB1 and CUL4 associated factor 6

increases expression

Parathion results in increased expression of DCAF6 mRNA

NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512

G

DCC netrin 1 receptor

increases methylation

Parathion results in increased methylation of DCC promoter

NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740

G

damage specific DNA binding protein 2

affects response to substance

DDB2 gene SNP affects the susceptibility to Parathion

NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631

G

D-aspartate oxidase

increases methylation

Parathion results in increased methylation of DDO promoter

NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095

G

DExD-box helicase 21

increases expression

Parathion results in increased expression of DDX21 mRNA

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

G

death effector domain containing 2

increases expression

Parathion results in increased expression of DEDD2 mRNA

NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714

G

delta(4)-desaturase, sphingolipid 1

increases expression

Parathion results in increased expression of DEGS1 mRNA

NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664

G

DENN domain containing 2B

decreases expression

Parathion results in decreased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

DENN domain containing 5B

increases expression

Parathion results in increased expression of DENND5B mRNA

NCBI chr 4:181,959,597...182,089,661
Ensembl chr 4:181,961,386...182,089,362

G

Dexi homolog

decreases expression

Parathion results in decreased expression of DEXI mRNA

NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738

G

dehydrogenase/reductase 7B

decreases expression

Parathion results in decreased expression of DHRS7B mRNA

NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076

G

DEXH-box helicase 58

increases methylation

Parathion results in increased methylation of DHX58 promoter

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

G

DIRAS family GTPase 2

increases methylation

Parathion results in increased methylation of DIRAS2 promoter

NCBI chr17:12,730,040...12,761,511
Ensembl chr17:12,725,149...12,761,663

G

DIRAS family GTPase 3

increases methylation

Parathion results in increased methylation of DIRAS3 promoter

NCBI chr 6:130,524,972...130,526,186
Ensembl chr 6:130,524,742...130,530,825

G

dickkopf WNT signaling pathway inhibitor 1

increases methylation

Parathion results in increased methylation of DKK1 promoter

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

dickkopf WNT signaling pathway inhibitor 4

decreases expression

Parathion results in decreased expression of DKK4 mRNA

NCBI chr16:69,403,215...69,406,580
Ensembl chr16:69,402,989...69,406,580

G

distal-less homeobox 5

increases methylation

Parathion results in increased methylation of DLX5 promoter

NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407

G

doublesex and mab-3 related transcription factor 2

increases methylation

Parathion results in increased methylation of DMRT2 promoter

NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131

G

dynein, axonemal, heavy chain 10

increases methylation

Parathion results in increased methylation of DNAH10 promoter

NCBI chr12:31,823,451...31,946,857
Ensembl chr12:31,822,733...32,007,069

G

dynein, axonemal, heavy chain 3

decreases methylation

Parathion results in decreased methylation of DNAH3 promoter

NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474

G

DnaJ heat shock protein family (Hsp40) member B8

increases methylation

Parathion results in increased methylation of DNAJB8 promoter

NCBI chr 4:120,681,918...120,685,108
Ensembl chr 4:120,681,926...120,687,552

G

DnaJ heat shock protein family (Hsp40) member C21

increases expression

Parathion results in increased expression of DNAJC21 mRNA

NCBI chr 2:59,419,507...59,446,746
Ensembl chr 2:59,419,510...59,446,752

G

DnaJ heat shock protein family (Hsp40) member C5 beta

increases methylation

Parathion results in increased methylation of DNAJC5B promoter

NCBI chr 2:101,973,726...102,066,275
Ensembl chr 2:101,973,793...102,066,275

G

dihydropyrimidinase

increases expression

Parathion results in increased expression of DPYS mRNA

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

dihydropyrimidinase-like 5

increases methylation

Parathion results in increased methylation of DPYSL5 promoter

NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422

G

dopamine receptor D1

increases methylation

Parathion results in increased methylation of DRD1 promoter

NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002

G

desmocollin 1

increases methylation

Parathion results in increased methylation of DSC1 promoter

NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494

G

desmocollin 3

increases methylation

Parathion results in increased methylation of DSC3 promoter

NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797

G

D-aminoacyl-tRNA deacylase 1

increases expression

Parathion results in increased expression of DTD1 mRNA

NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659

G

dual oxidase maturation factor 2

increases methylation

Parathion results in increased methylation of DUOXA2 promoter

NCBI chr 3:109,245,337...109,249,055
Ensembl chr 3:109,245,476...109,248,968

G

dual specificity phosphatase 3

increases expression

Parathion results in increased expression of DUSP3 mRNA

NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962

G

dual specificity phosphatase 4

increases methylation

Parathion results in increased methylation of DUSP4 promoter

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

dual specificity phosphatase 6

increases methylation

Parathion results in increased methylation of DUSP6 promoter

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dishevelled segment polarity protein 1

multiple interactions

[Parathion co-treated with Estrogens] results in increased expression of DVL1 mRNA

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

G

dishevelled segment polarity protein 2

increases expression
multiple interactions

Parathion results in increased expression of DVL2 protein
Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein]

NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820

G

dual specificity tyrosine phosphorylation regulated kinase 1B

increases methylation

Parathion results in increased methylation of DYRK1B promoter

NCBI chr 1:83,479,168...83,497,011
Ensembl chr 1:83,479,147...83,487,169

G

dual specificity tyrosine phosphorylation regulated kinase 2

decreases expression

Parathion results in decreased expression of DYRK2 mRNA

NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106

G

DAZ interacting zinc finger protein 1

increases methylation

Parathion results in increased methylation of DZIP1 promoter

NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066

G

E2F transcription factor 1

decreases expression

Parathion results in decreased expression of E2F1 mRNA

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

enoyl CoA hydratase domain containing 3

increases methylation

Parathion results in increased methylation of ECHDC3 promoter

NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516

G

enoyl-CoA delta isomerase 2

increases expression

Parathion results in increased expression of ECI2 mRNA

NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781

G

eukaryotic translation elongation factor 1 delta

increases expression

Parathion results in increased expression of EEF1D mRNA

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

epidermal growth factor receptor

multiple interactions
increases expression

[Parathion co-treated with Estradiol] results in increased expression of EGFR protein; Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein]

PMID:17390078 PMID:17622325

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

eukaryotic translation initiation factor 3, subunit H

increases expression

Parathion results in increased expression of EIF3H mRNA

NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451

G

eukaryotic translation initiation factor 4A2

increases expression

Parathion results in increased expression of EIF4A2 mRNA

NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781

G

engulfment and cell motility 2

decreases methylation

Parathion results in decreased methylation of ELMO2 promoter

NCBI chr 3:154,023,661...154,061,259
Ensembl chr 3:154,023,661...154,061,185

G

ELOVL fatty acid elongase 1

increases methylation
decreases expression

Parathion results in increased methylation of ELOVL1 promoter
Parathion results in decreased expression of ELOVL1 mRNA

PMID:22847954 PMID:34813904

NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958

G

ELOVL fatty acid elongase 3

decreases expression

Parathion results in decreased expression of ELOVL3 mRNA

NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115

G

ER membrane protein complex subunit 3

decreases expression

Parathion results in decreased expression of EMC3 mRNA

NCBI chr 4:146,663,065...146,678,976
Ensembl chr 4:146,663,067...146,679,029

G

enolase-phosphatase 1

increases expression

Parathion results in increased expression of ENOPH1 mRNA

NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

increases expression

Parathion results in increased expression of ENPP1 mRNA

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

endosomal transmembrane epsin interactor 3

increases methylation

Parathion results in increased methylation of ENTREP3 promoter

NCBI chr 2:174,588,984...174,595,281
Ensembl chr 2:174,589,337...174,595,281

G

E1A binding protein p400

increases expression

Parathion results in increased expression of EP400 mRNA

NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861

G

erythrocyte membrane protein band 4.1-like 1

increases methylation

Parathion results in increased methylation of EPB41L1 promoter

NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721

G

Eph receptor A4

increases methylation

Parathion results in increased methylation of EPHA4 promoter

NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139

G

Eph receptor A7

increases methylation

Parathion results in increased methylation of EPHA7 promoter

NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112

G

epoxide hydrolase 4

increases methylation

Parathion results in increased methylation of EPHX4 promoter

NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022

G

EGFR pathway substrate 8, signaling adaptor

increases methylation

Parathion results in increased methylation of EPS8 promoter

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

eosinophil peroxidase

increases methylation

Parathion results in increased methylation of EPX promoter

NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952

G

ELKS/RAB6-interacting/CAST family member 2

increases methylation

Parathion results in increased methylation of ERC2 promoter

NCBI chr16:2,812,712...3,673,624
Ensembl chr16:2,848,620...3,670,776

G

endoplasmic reticulum protein 27

increases methylation

Parathion results in increased methylation of ERP27 promoter

NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660

G

endogenous retrovirus group FRD member 1, envelope

decreases methylation

Parathion results in decreased methylation of ERVFRD-1 promoter

NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264

G

estrogen receptor 1

decreases activity

Parathion results in decreased activity of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

epithelial splicing regulatory protein 1

increases methylation

Parathion results in increased methylation of ESRP1 promoter

NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062

G

extended synaptotagmin 3

increases methylation

Parathion results in increased methylation of ESYT3 promoter

NCBI chr 8:99,870,418...99,917,298
Ensembl chr 8:99,871,149...99,917,232

G

ethanolamine kinase 2

increases expression

Parathion results in increased expression of ETNK2 mRNA

NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037

G

eva-1 homolog C

increases methylation

Parathion results in increased methylation of EVA1C promoter

NCBI chr11:30,089,510...30,163,596
Ensembl chr11:30,089,365...30,163,596

G

EYA transcriptional coactivator and phosphatase 4

increases methylation

Parathion results in increased methylation of EYA4 promoter

NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976

G

ezrin

multiple interactions
increases expression

Atropine inhibits the reaction [Parathion results in increased expression of EZR protein]

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor XII

increases expression

Parathion results in increased expression of F12 mRNA

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

G

coagulation factor V

increases expression

Parathion results in increased expression of F5 mRNA

NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317

G

fatty acid amide hydrolase

decreases activity

Parathion results in decreased activity of FAAH protein

PMID:23933531 PMID:26215119

NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677

G

fatty acid binding protein 5

increases methylation

Parathion results in increased methylation of FABP5 promoter

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid binding protein 7

increases methylation

Parathion results in increased methylation of FABP7 promoter

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

family with sequence similarity 118, member A

increases methylation

Parathion results in increased methylation of FAM118A promoter

NCBI chr 7:116,152,448...116,178,976
Ensembl chr 7:116,146,716...116,178,971

G

family with sequence similarity 13, member A

increases expression

Parathion results in increased expression of FAM13A mRNA

NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860

G

family with sequence similarity 151, member A

increases methylation

Parathion results in increased methylation of FAM151A promoter

NCBI chr 5:121,514,804...121,527,555
Ensembl chr 5:121,514,804...121,527,555

G

family with sequence similarity 221, member A

increases methylation

Parathion results in increased methylation of FAM221A promoter

NCBI chr 4:78,337,296...78,358,918
Ensembl chr 4:78,337,296...78,358,909

G

family with sequence similarity 25, member A

decreases expression

Parathion results in decreased expression of FAM25C mRNA

NCBI chr16:9,680,668...9,684,474
Ensembl chr16:9,680,668...9,684,474

G

FAM3 metabolism regulating signaling molecule A

increases expression

Parathion results in increased expression of FAM3A mRNA

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

G

FAM3 metabolism regulating signaling molecule B

increases methylation

Parathion results in increased methylation of FAM3B promoter

NCBI chr11:36,831,532...36,863,902
Ensembl chr11:36,831,532...36,869,713

G

FAM3 metabolism regulating signaling molecule D

increases methylation

Parathion results in increased methylation of FAM3D promoter

NCBI chr15:16,538,881...16,574,468
Ensembl chr15:16,539,489...16,573,034

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

increases methylation

Parathion results in increased methylation of FARP1 promoter

NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299

G

FAT atypical cadherin 1

decreases expression

Parathion results in decreased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

F-box protein 21

increases expression

Parathion results in increased expression of FBXO21 mRNA

NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133

G

F-box protein 25

decreases methylation

Parathion results in decreased methylation of FBXO25 promoter

NCBI chr16:75,666,062...75,701,770
Ensembl chr16:75,667,904...75,701,696

G

Fc gamma binding protein

increases methylation

Parathion results in increased methylation of FCGBP promoter

NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083

G

FERM domain containing kindlin 1

increases methylation

Parathion results in increased methylation of FERMT1 promoter

NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555

G

fetuin B

increases expression

Parathion results in increased expression of FETUB mRNA

NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135

G

fibroblast growth factor 12

increases methylation

Parathion results in increased methylation of FGF12 promoter

NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607

G

fibroblast growth factor receptor-like 1

increases methylation

Parathion results in increased methylation of FGFRL1 promoter

NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928

G

fidgetin, microtubule severing factor

increases methylation

Parathion results in increased methylation of FIGN promoter

NCBI chr 3:48,637,510...48,760,772
Ensembl chr 3:48,642,496...48,760,787

G

FKBP prolyl isomerase 5

increases expression

Parathion results in increased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

flotillin 1

increases expression

Parathion results in increased expression of FLOT1 mRNA

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

G

fibronectin leucine rich transmembrane protein 2

increases methylation

Parathion results in increased methylation of FLRT2 promoter

NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785

G

Fms related receptor tyrosine kinase 3

increases methylation

Parathion results in increased methylation of FLT3 promoter

NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474

G

flavin containing dimethylaniline monoxygenase 1

increases expression

Parathion results in increased expression of FMO1 mRNA

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

flavin containing dimethylaniline monoxygenase 2

increases expression

Parathion results in increased expression of FMO2 mRNA

NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308

G

fibronectin type III domain containing 9

increases methylation

Parathion results in increased methylation of FNDC9 promoter

NCBI chr10:30,664,435...30,668,213
Ensembl chr10:30,667,091...30,667,771

G

folliculin interacting protein 2

increases expression

Parathion results in increased expression of FNIP2 mRNA

NCBI chr 2:164,596,557...164,708,147
Ensembl chr 2:164,598,906...164,707,901

G

forkhead box A1

increases methylation

Parathion results in increased methylation of FOXA1 promoter

NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188

G

forkhead box B1

increases methylation

Parathion results in increased methylation of FOXB1 promoter

NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781

G

forkhead box D3

increases methylation

Parathion results in increased methylation of FOXD3 promoter

NCBI chr 5:114,335,084...114,337,450
Ensembl chr 5:114,335,408...114,336,817

G

forkhead box J1

increases methylation

Parathion results in increased methylation of FOXJ1 promoter

NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237

G

forkhead box O4

increases methylation

Parathion results in increased methylation of FOXO4 promoter

NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115

G

folylpolyglutamate synthase

decreases expression

Parathion results in decreased expression of FPGS mRNA

NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563

G

FERM domain containing 5

increases methylation

Parathion results in increased methylation of FRMD5 promoter

NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498

G

follistatin-like 1

increases methylation

Parathion results in increased methylation of FSTL1 promoter

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

follistatin-like 5

increases methylation

Parathion results in increased methylation of FSTL5 promoter

NCBI chr 2:160,857,989...161,526,589
Ensembl chr 2:160,856,291...161,526,589

G

FXYD domain-containing ion transport regulator 7

increases methylation

Parathion results in increased methylation of FXYD7 promoter

NCBI chr 1:86,277,678...86,286,954
Ensembl chr 1:86,277,678...86,286,954

G

FYN binding protein 1

decreases methylation

Parathion results in decreased methylation of FYB1 promoter

NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629

G

frizzled class receptor 9

increases methylation

Parathion results in increased methylation of FZD9 promoter

NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398

G

GABA type A receptor associated protein like 1

increases expression

Parathion results in increased expression of GABARAPL1 mRNA

NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450

G

gamma-aminobutyric acid type B receptor subunit 2

increases expression

Parathion results in increased expression of GABBR2 mRNA

NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104

G

gamma-aminobutyric acid type A receptor subunit alpha 2

increases methylation

Parathion results in increased methylation of GABRA2 promoter

NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944

G

gamma-aminobutyric acid type A receptor subunit delta

decreases expression

Parathion results in decreased expression of GABRD mRNA

NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411

G

gamma-aminobutyric acid type A receptor subunit rho 2

increases expression

Parathion results in increased expression of GABRR2 mRNA

NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809

G

glutamate decarboxylase 1

increases methylation

Parathion results in increased methylation of GAD1 promoter

NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333

G

growth arrest and DNA-damage-inducible, gamma

increases methylation

Parathion results in increased methylation of GADD45G promoter

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

polypeptide N-acetylgalactosaminyltransferase 10

increases methylation

Parathion results in increased methylation of GALNT10 promoter

NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013

G

polypeptide N-acetylgalactosaminyltransferase 6

decreases methylation

Parathion results in decreased methylation of GALNT6 promoter

NCBI chr 7:131,789,836...131,828,077
Ensembl chr 7:131,789,839...131,819,661

G

galanin-like peptide

increases methylation

Parathion results in increased methylation of GALP promoter

NCBI chr 1:67,684,023...67,703,121
Ensembl chr 1:67,684,025...67,702,269

G

galanin receptor 1

increases methylation

Parathion results in increased methylation of GALR1 promoter

NCBI chr18:75,772,021...75,787,577
Ensembl chr18:75,772,023...75,787,577

G

GRB2 associated regulator of MAPK1 subtype 1

increases methylation

Parathion results in increased methylation of GAREM1 promoter

NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345

G

growth arrest-specific 2 like 2

increases methylation

Parathion results in increased methylation of GAS2L2 promoter

NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881

G

GATA binding protein 4

increases methylation

Parathion results in increased methylation of GATA4 promoter

NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636

G

GATA binding protein 5

increases methylation

Parathion results in increased methylation of GATA5 promoter

NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751

G

golgi brefeldin A resistant guanine nucleotide exchange factor 1

decreases expression

Parathion results in decreased expression of GBF1 mRNA

NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042

G

globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)

increases methylation

Parathion results in increased methylation of GBGT1 promoter

NCBI chr 3:11,826,131...11,829,745

G

GC, vitamin D binding protein

affects response to substance

GC gene SNP affects the susceptibility to Parathion

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

G

GTP cyclohydrolase 1

increases expression

Parathion results in increased expression of GCH1 mRNA

NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases methylation

Parathion results in increased methylation of GCNT3 promoter

NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562

G

ganglioside-induced differentiation-associated protein 1-like 1

increases methylation

Parathion results in increased methylation of GDAP1L1 promoter

NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711

G

glycerophosphodiester phosphodiesterase 1

increases expression

Parathion results in increased expression of GDE1 mRNA

NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429

G

growth differentiation factor 7

increases methylation

Parathion results in increased methylation of GDF7 promoter

NCBI chr 6:31,171,495...31,182,484
Ensembl chr 6:31,178,119...31,182,447

G

growth hormone releasing hormone

increases methylation

Parathion results in increased methylation of GHRH promoter

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

G

gap junction protein, alpha 3

increases methylation

Parathion results in increased methylation of GJA3 promoter

NCBI chr15:31,181,360...31,206,820
Ensembl chr15:31,181,369...31,206,810

G

gap junction protein, alpha 4

increases methylation

Parathion results in increased methylation of GJA4 promoter

NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925

G

gap junction protein, beta 2

increases methylation

Parathion results in increased methylation of GJB2 promoter

NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177

G

gap junction protein, gamma 1

decreases methylation

Parathion results in decreased methylation of GJC1 promoter

NCBI chr10:87,758,192...87,785,443
Ensembl chr10:87,760,528...87,785,867

G

glycerol kinase

increases expression

Parathion results in increased expression of GK mRNA

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

G kinase anchoring protein 1

increases expression

Parathion results in increased expression of GKAP1 mRNA

NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679

G

galactosidase, beta 1-like 3

increases methylation

Parathion results in increased methylation of GLB1L3 promoter

NCBI chr 8:25,179,165...25,220,904
Ensembl chr 8:25,179,165...25,220,904

G

GLIPR1 like 1

increases methylation

Parathion results in increased methylation of GLIPR1L1 promoter

NCBI chr 7:47,550,637...47,577,611
Ensembl chr 7:47,550,631...47,577,617

G

GLIS family zinc finger 1

increases methylation

Parathion results in increased methylation of GLIS1 promoter

NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141

G

glutaredoxin

increases expression

Parathion results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glycosyltransferase 1 domain containing 1

increases methylation

Parathion results in increased methylation of GLT1D1 promoter

NCBI chr12:28,975,984...29,049,707
Ensembl chr12:28,975,988...29,049,695

G

glutamate dehydrogenase 1

increases expression

Parathion results in increased expression of GLUD1 mRNA

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

glia maturation factor, gamma

decreases methylation

Parathion results in decreased methylation of GMFG promoter

NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183

G

G protein subunit alpha i1

increases methylation

Parathion results in increased methylation of GNAI1 promoter

NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

increases expression

Parathion results in increased expression of GNE mRNA

NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499

G

G protein subunit gamma 7

increases methylation

Parathion results in increased methylation of GNG7 promoter

NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240

G

glycerol-3-phosphate acyltransferase 4

increases expression

Parathion results in increased expression of GPAT4 mRNA

NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901

G

glycerophosphocholine phosphodiesterase 1

increases expression

Parathion results in increased expression of GPCPD1 mRNA

NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517

G

G patch domain and KOW motifs

decreases methylation

Parathion results in decreased methylation of GPKOW promoter

NCBI chr X:14,791,601...14,806,384
Ensembl chr X:14,791,610...14,806,384

G

glycoprotein m6a

increases methylation

Parathion results in increased methylation of GPM6A promoter

NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475

G

G protein-coupled receptor 137B

decreases methylation

Parathion results in decreased methylation of GPR137B promoter

NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835

G

G protein-coupled receptor 150

increases methylation

Parathion results in increased methylation of GPR150 promoter

NCBI chr 2:5,546,304...5,550,889
Ensembl chr 2:5,548,578...5,550,714

G

G protein-coupled receptor 15 ligand

increases methylation

Parathion results in increased methylation of GPR15LG promoter

NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876

G

G protein-coupled receptor 45

increases methylation

Parathion results in increased methylation of GPR45 promoter

NCBI chr 9:45,221,364...45,309,713
Ensembl chr 9:45,306,237...45,309,706

G

G protein-coupled receptor 55

increases methylation

Parathion results in increased methylation of GPR55 promoter

NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613

G

G protein-coupled receptor 83

increases methylation

Parathion results in increased methylation of GPR83 promoter

NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028

G

glutamic--pyruvic transaminase

increases expression

Parathion results in increased expression of GPT mRNA

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

growth factor receptor bound protein 14

increases methylation

Parathion results in increased methylation of GRB14 promoter

NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889

G

glutamate ionotropic receptor AMPA type subunit 4

increases methylation

Parathion results in increased methylation of GRIA4 promoter

NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979

G

glutamate ionotropic receptor kainate type subunit 3

increases methylation

Parathion results in increased methylation of GRIK3 promoter

NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307

G

glutamate ionotropic receptor NMDA type subunit 1

decreases expression

Parathion results in decreased expression of GRIN1 mRNA

NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603

G

glutamate ionotropic receptor NMDA type subunit 2C

increases methylation

Parathion results in increased methylation of GRIN2C promoter

NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427

G

G protein-coupled receptor kinase 3

increases methylation

Parathion results in increased methylation of GRK3 promoter

NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262

G

G protein-coupled receptor kinase 5

decreases expression

Parathion results in decreased expression of GRK5 mRNA

NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701

G

glutamate metabotropic receptor 2

increases methylation

Parathion results in increased methylation of GRM2 promoter

NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146

G

glutamate metabotropic receptor 7

increases methylation

Parathion results in increased methylation of GRM7 promoter

NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344

G

goosecoid homeobox

increases methylation

Parathion results in increased methylation of GSC promoter

NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111

G

glutathione S-transferase alpha 2

increases expression

Parathion results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase mu 1

increases expression

Parathion results in increased expression of GSTM1 mRNA

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase, mu 5-like

increases methylation

Parathion results in increased methylation of GSTM5 promoter

NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

increases expression
decreases expression

Parathion results in increased expression of GSTP1 mRNA
Parathion results in decreased expression of GSTP1 mRNA

PMID:17982697 PMID:34813904

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 2

increases expression

Parathion results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

GS homeobox 2

increases methylation

Parathion results in increased methylation of GSX2 promoter

NCBI chr14:33,123,799...33,126,151
Ensembl chr14:33,124,381...33,126,105

G

general transcription factor IIIC subunit 2

increases expression

Parathion results in increased expression of GTF3C2 mRNA

NCBI chr 6:25,196,439...25,221,338
Ensembl chr 6:25,197,268...25,220,490

G

gametocyte specific factor 1-like

increases methylation

Parathion results in increased methylation of GTSF1L promoter

NCBI chr 3:151,736,020...151,738,715
Ensembl chr 3:151,735,997...151,736,863

G

guanylate cyclase 1 soluble subunit alpha 2

increases methylation

Parathion results in increased methylation of GUCY1A2 promoter

NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203

G

guanylate cyclase 2E

increases methylation

Parathion results in increased methylation of GUCY2D promoter

NCBI chr10:53,954,918...53,975,576
Ensembl chr10:53,959,010...53,974,067

G

glucuronidase, beta

decreases expression

Parathion results in decreased expression of GUSB mRNA

NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905

G

glycophorin C

increases expression

Parathion results in increased expression of GYPC mRNA

NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204

G

H19 imprinted maternally expressed transcript

decreases methylation

Parathion results in decreased methylation of H19 promoter

NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134

G

H2B clustered histone 9

decreases expression

Parathion results in decreased expression of H2BC9 mRNA

NCBI chr17:42,470,593...42,478,590

G

hyaluronan binding protein 2

decreases expression

Parathion results in decreased expression of HABP2 mRNA

NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160

G

histidine ammonia lyase

increases methylation

Parathion results in increased methylation of HAL promoter

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hyaluronan and proteoglycan link protein 3

increases methylation

Parathion results in increased methylation of HAPLN3 promoter

NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177

G

hypocretin receptor 1

increases methylation

Parathion results in increased methylation of HCRTR1 promoter

NCBI chr 5:142,477,214...142,486,674
Ensembl chr 5:142,477,214...142,486,674

G

histone deacetylase 5

increases methylation

Parathion results in increased methylation of HDAC5 promoter

NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235

G

HEPACAM family member 2

decreases methylation

Parathion results in decreased methylation of HEPACAM2 promoter

NCBI chr 4:31,446,195...31,480,859
Ensembl chr 4:31,446,169...31,480,953

G

hes family bHLH transcription factor 6

decreases methylation
decreases expression

Parathion results in decreased methylation of HES6 promoter
Parathion results in decreased expression of HES6 mRNA

PMID:22847954 PMID:34813904

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

Hedgehog-interacting protein

increases methylation

Parathion results in increased methylation of HHIP promoter

NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528

G

HHIP-like 1

increases methylation

Parathion results in increased methylation of HHIPL1 promoter

NCBI chr 6:127,219,616...127,243,839
Ensembl chr 6:127,220,014...127,242,564

G

heat shock protein nuclear import factor hikeshi

decreases expression

Parathion results in decreased expression of HIKESHI mRNA

NCBI chr 1:143,825,399...143,849,361
Ensembl chr 1:143,825,923...143,849,363

G

histone cluster 1, H4m

decreases expression

Parathion results in decreased expression of H4C1 mRNA

NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958

G

HLF transcription factor, PAR bZIP family member

increases methylation

Parathion results in increased methylation of HLF promoter

NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935

G

H2.0-like homeobox

increases methylation

Parathion results in increased methylation of HLX promoter

NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750

G

high mobility group box 1

increases expression

Parathion results in increased expression of HMGB1 mRNA

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

Parathion results in increased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

heme oxygenase 1

increases expression

Parathion results in increased expression of HMOX1 protein

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079