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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-isopropylphenol
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Accession:CHEBI:167172 term browser browse the term
Definition:A member of the class of phenols that is phenol which is carrying an isopropyl group at position 4.
Synonyms:exact_synonym: 4-(propan-2-yl)phenol
 related_synonym: 1-hydroxy-4-isopropylbenzene;   4-(1-methylethyl)phenol;   4-hydroxycumene;   Formula=C9H12O;   InChI=1S/C9H12O/c1-7(2)8-3-5-9(10)6-4-8/h3-7,10H,1-2H3;   InChIKey=YQUQWHNMBPIWGK-UHFFFAOYSA-N;   SMILES=CC(C)C1=CC=C(O)C=C1;   p-cumenol;   p-hydroxycumene;   p-isopropylphenol
 xref: CAS:99-89-8;   Chemspider:7185;   FooDB:FDB005302;   HMDB:HMDB0031446
 xref_mesh: MESH:C028690
 xref: PMID:16567400;   PMID:26219367;   PMID:27486708;   PMID:29225186;   PMID:30519707;   PMID:32970353;   Reaxys:1363564


show annotations for term's descendants           Sort by:
4-isopropylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 4-isopropylphenol inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein] CTD PMID:27561732 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases glutathionylation ISO CYP2C8 protein results in increased glutathionylation of 4-isopropylphenol CTD PMID:23470418
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases glutathionylation ISO CYP3A4 protein results in increased glutathionylation of 4-isopropylphenol CTD PMID:23470418 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions
affects binding		 ISO 4-isopropylphenol binds to and results in increased activity of ESRRG protein; 4-isopropylphenol inhibits the reaction [afimoxifene binds to and results in decreased activity of ESRRG protein]
4-isopropylphenol binds to ESRRG protein		 CTD PMID:27486708 PMID:31127318 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397 		JBrowse link
G Or5d18 olfactory receptor family 5 subfamily D member 18 multiple interactions ISO 4-isopropylphenol binds to and results in increased activity of OR5D18 protein CTD PMID:21142015 NCBI chr 3:73,516,522...73,517,463
Ensembl chr 3:73,516,364...73,519,858
Ensembl chr 3:73,516,364...73,519,858 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        food additive 16831
          flavouring agent 4866
            4-isopropylphenol 5
              4-isopropylphenyl sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            organic hydride 18687
                              organic fundamental parent 18687
                                hydrocarbon 18438
                                  cyclic hydrocarbon 17231
                                    monocyclic hydrocarbon 6164
                                      annulene 5817
                                        aromatic annulene 5817
                                          benzene 5817
                                            alkylbenzene 3538
                                              cumene 101
                                                4-isopropylphenol 5
                                                  4-isopropylphenyl sulfate 0
paths to the root