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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:saccharolipid
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Accession:CHEBI:166828 term browser browse the term
Definition:Lipids that contain a carbohydrate moiety.
Synonyms:related_synonym: saccharolipids
 xref: Wikipedia:Saccharolipid



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eritoran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7b ATPase copper transporting beta multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL1B protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL6 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of MYD88 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of PTGS2 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of RELA protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TLR4 protein]; eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TNF protein] CTD PMID:38761876 NCBI chr16:76,654,725...76,726,092
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of BAX protein] CTD PMID:38761876 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in decreased expression of BCL2 protein] CTD PMID:38761876 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp1 caspase 1 multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP1 protein] CTD PMID:38761876 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP3 protein] CTD PMID:38761876 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP8 protein] CTD PMID:38761876 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO eritoran inhibits the reaction [Azathioprine results in increased expression of GPT protein]; eritoran inhibits the reaction [Diclofenac results in increased expression of GPT protein]; eritoran inhibits the reaction [Dicloxacillin results in increased expression of GPT protein]; eritoran inhibits the reaction [Halothane results in increased expression of GPT protein] CTD PMID:24184165 PMID:24747151 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of GSDMD protein] CTD PMID:38761876 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:107,542,083...107,547,055
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL1B protein] CTD PMID:38761876 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of IL6 protein] CTD PMID:38761876 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of MLKL protein] CTD PMID:38761876 NCBI chr19:56,186,860...56,213,886
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of MYD88 protein] CTD PMID:38761876 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in decreased expression of BCL2 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP1 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP3 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of CASP8 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased cleavage of GSDMD protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of MLKL protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of RIPK3 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of BAX protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of TLR4 protein] CTD PMID:38761876 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of PTGS2 protein] CTD PMID:38761876 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of RELA protein] CTD PMID:38761876 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of and results in increased phosphorylation of RIPK3 protein] CTD PMID:38761876 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TLR4 protein]; eritoran inhibits the reaction [NLRP3 mutant form results in increased expression of TLR4 protein] CTD PMID:38761876 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO eritoran inhibits the reaction [ATP7B mutant form results in increased expression of TNF protein] CTD PMID:38761876 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
lipid As term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Lipid A results in increased expression of CCL3 mRNA
anacetrapib inhibits the reaction [Lipid A results in increased expression of CCL3 mRNA]
CTD PMID:20448206 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IFNG mRNA; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IFNG protein; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IFNG mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IFNG protein
Lipid A results in increased expression of IFNG mRNA; Lipid A results in increased expression of IFNG protein
CTD PMID:16299289 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il12a interleukin 12A multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL12A mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IL12A mRNA; Lipid A results in increased expression of [IL12A protein binds to IL12B protein]
Lipid A results in increased expression of IL12A mRNA
CTD PMID:16299289 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL12B mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IL12B mRNA; Lipid A results in increased expression of [IL12A protein binds to IL12B protein]
Lipid A results in increased expression of IL12B mRNA
CTD PMID:16299289 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il15 interleukin 15 multiple interactions
increases expression
ISO [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL15 mRNA; [heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine co-treated with Lipid A] results in increased expression of IL15 mRNA
Lipid A results in increased expression of IL15 mRNA
CTD PMID:16299289 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il18 interleukin 18 increases expression ISO Lipid A results in increased expression of IL18 mRNA CTD PMID:16299289 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO anacetrapib inhibits the reaction [Lipid A results in increased expression of IL6 mRNA] CTD PMID:20448206 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO anacetrapib inhibits the reaction [Lipid A results in increased expression of TNF mRNA] CTD PMID:20448206 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
sulfolipid I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 affects binding
multiple interactions
ISO NOD2 protein binds to sulfolipid I
sulfolipid I inhibits the reaction [NOD2 protein binds to Sulfoglycosphingolipids]
CTD PMID:23880069 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      atom 19897
        nonmetal atom 19820
          carbon atom 19772
            organic molecular entity 19772
              lipid 18006
                saccharolipid 25
                  Nuezhenide 0
                  acyl alpha,alpha-trehalose derivative + 1
                  acyl sugars + 0
                  acylaminosugars 0
                  lipid As + 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19836
                    p-block element atom 19836
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            lipid 18006
                              saccharolipid 25
                                Nuezhenide 0
                                acyl alpha,alpha-trehalose derivative + 1
                                acyl sugars + 0
                                acylaminosugars 0
                                lipid As + 24
paths to the root