Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:carbon dioxide
go back to main search page
Accession:CHEBI:16526 term browser browse the term
Definition:A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.
Synonyms:exact_synonym: dioxidocarbon;   methanedione
 related_synonym: CO2;   E 290;   E290;   Formula=CO2;   InChI=1S/CO2/c2-1-3;   InChIKey=CURLTUGMZLYLDI-UHFFFAOYSA-N;   R-744;   SMILES=O=C=O;   carbonic anhydride
 alt_id: CHEBI:13282;   CHEBI:13283;   CHEBI:13284;   CHEBI:13285;   CHEBI:23011;   CHEBI:3283;   CHEBI:48829
 xref: Beilstein:1900390;   CAS:124-38-9;   Drug_Central:4256;   Gmelin:989;   HMDB:HMDB0001967;   KEGG:C00011;   KEGG:D00004
 xref_mesh: MESH:D002245
 xref: MetaCyc:CARBON-DIOXIDE;   MolBase:752;   PDBeChem:CO2;   PMID:10826146;   PMID:11094503;   PMID:11584085;   PMID:11802652;   PMID:14639145;   PMID:15050588;   PMID:16591971;   PMID:16656478;   PMID:16659660;   PMID:17190796;   PMID:17448243;   PMID:17878298;   PMID:17884085;   PMID:19043767;   PMID:19259576;   PMID:19854893;   PMID:23384758;   PMID:23828359;   PMID:24258718;   PMID:8482095;   PMID:8818713;   PMID:8869828;   PMID:9611769;   PMID:9730350;   PPDB:119;   Reaxys:1900390;   UM-BBD_compID:c0131;   Wikipedia:Carbon_dioxide


show annotations for term's descendants           Sort by:
carbon dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression		 EXP 3-n-butylphthalide promotes the reaction [Carbon Dioxide results in increased expression of AKT1 protein] CTD PMID:37661366 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 EXP 3-n-butylphthalide promotes the reaction [Carbon Dioxide results in increased expression of BCL2 protein] CTD PMID:37661366 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein] CTD PMID:24718106 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases secretion		 EXP Carbon Dioxide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased secretion of CALCA protein]
Carbon Dioxide results in increased secretion of CALCA protein		 CTD PMID:18052948 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein] CTD PMID:24718106 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein] CTD PMID:24718106 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone increases response to substance ISO CRH protein results in increased susceptibility to Carbon Dioxide CTD PMID:8957205 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein] CTD PMID:24718106 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein] CTD PMID:24718106 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression		 EXP
ISO		 3-n-butylphthalide promotes the reaction [Carbon Dioxide results in increased expression of IL2 mRNA]; 3-n-butylphthalide promotes the reaction [Carbon Dioxide results in increased expression of IL2 protein]
Carbon Dioxide results in increased expression of IL2 mRNA; Carbon Dioxide results in increased expression of IL2 protein		 CTD PMID:37661366 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK1 mRNA; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK1 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK1 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK1 protein] CTD PMID:24718106 PMID:25004876 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK3 mRNA; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK3 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK3 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK3 protein] CTD PMID:24718106 PMID:25004876 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir29a microRNA 29a multiple interactions ISO [[Vehicle Emissions results in increased abundance of Air Pollutants] which results in increased abundance of Carbon Dioxide] which results in increased expression of MIR29A mRNA CTD PMID:29980036 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Neil1 nei-like DNA glycosylase 1 affects abundance ISO NEIL1 affects the abundance of Carbon Dioxide CTD PMID:21285402 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
G Ngb neuroglobin affects binding ISO Carbon Dioxide binds to [Heme binds to NGB protein] CTD PMID:16684569 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [[GW 7647 results in increased oxidation of Palmitic Acid] which results in increased abundance of Carbon Dioxide] CTD PMID:21324916 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 multiple interactions ISO [RAPGEF3 protein affects the susceptibility to Dietary Fats] which affects the chemical synthesis of Carbon Dioxide CTD PMID:27381457 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 affects response to substance EXP SLC9A1 protein affects the susceptibility to Carbon Dioxide CTD PMID:16831598 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[[Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein binds to peroxycarbonic acid]] which results in increased reduction of peroxycarbonic acid] which results in increased chemical synthesis of Carbonates; [[Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein binds to peroxycarbonic acid]] which results in increased reduction of peroxycarbonic acid; [[SOD1 protein results in increased metabolism of Hydrogen Peroxide] results in increased oxidation of [Bicarbonates co-treated with Carbon Dioxide]] which results in increased chemical synthesis of Carbonates; [Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein binds to peroxycarbonic acid]; [Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein results in increased metabolism of Hydrogen Peroxide]; [SOD1 protein results in increased metabolism of Hydrogen Peroxide] results in increased oxidation of [Bicarbonates co-treated with Carbon Dioxide] CTD PMID:19243126 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein multiple interactions ISO [[Vehicle Emissions results in increased abundance of Air Pollutants] which results in increased abundance of Carbon Dioxide] which affects the expression of SYNCRIP mRNA CTD PMID:29980036 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein] CTD PMID:24718106 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Carbon Dioxide results in increased expression of TPI1 mRNA CTD PMID:14762718 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Trh thyrotropin releasing hormone increases response to substance ISO TRH protein results in increased susceptibility to Carbon Dioxide CTD PMID:8957205 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity EXP Carbon Dioxide results in increased activity of TRPA1 protein CTD PMID:20881114 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 affects response to substance EXP TRPV1 protein affects the susceptibility to Carbon Dioxide CTD PMID:16831598 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        solvent 17252
          carbon dioxide 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbon oxide 126
                                    carbon dioxide 25
paths to the root