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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dGTP
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Accession:CHEBI:16497 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxyguanosine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-deoxy-GTP;   2'-deoxyguanosine 5'-triphosphate;   2'-deoxyguanosine triphosphate;   Deoxyguanosine 5'-triphosphate;   Deoxyguanosine triphosphate;   Formula=C10H16N5O13P3;   InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1;   InChIKey=HAAZLUGHYHWQIW-KVQBGUIXSA-N;   SMILES=NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)N1;   deoxy-GTP
 alt_id: CHEBI:10497;   CHEBI:14076;   CHEBI:19247
 xref: CAS:2564-35-4;   Chemspider:58613;   DrugBank:DB02181;   ECMDB:ECMDB01440;   FooDB:FDB022623;   HMDB:HMDB0001440;   KEGG:C00286;   KNApSAcK:C00019346
 xref_mesh: MESH:C029603
 xref: PDBeChem:DGT;   PMID:11096070;   PMID:15708794;   PMID:17354649;   PMID:22844265;   PMID:24141705;   PMID:28373271;   PMID:31019074;   PMID:32402273;   PMID:33405358;   PMID:6783298;   PMID:7929110;   Reaxys:73481;   Wikipedia:Deoxyguanosine_triphosphate;   YMDB:YMDB00744
 cyclic_relationship: is_conjugate_acid_of CHEBI:57794


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dGTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 decreases abundance ISO SAMHD1 protein results in decreased abundance of deoxyguanosine triphosphate CTD PMID:26342080 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        biochemical role 19596
          metabolite 19558
            eukaryotic metabolite 19380
              plant metabolite 17988
                dGTP 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      chalcogen 19587
                        oxygen atom 19587
                          oxygen molecular entity 19587
                            hydroxides 19390
                              oxoacid 18821
                                pnictogen oxoacid 14983
                                  phosphorus oxoacid 14581
                                    phosphoric acids 13915
                                      phosphoric acid 13923
                                        phosphoric acid derivative 13828
                                          phosphate 13820
                                            organic phosphate 13820
                                              carbohydrate phosphate 1871
                                                phospho sugar 1714
                                                  aldose phosphate 1713
                                                    aldopentose phosphate 1705
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                purine 2'-deoxyribonucleoside 5'-triphosphate 1
                                                                  dGTP 1
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