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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:barbituric acid
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Accession:CHEBI:16294 term browser browse the term
Definition:A barbiturate, the structure of which is that of perhydropyrimidine substituted at C-2, -4 and -6 by oxo groups. Barbituric acid is the parent compound of barbiturate drugs, although it is not itself pharmacologically active.
Synonyms:related_synonym: 2,4,6(1H,3H,5H)-pyrimidinetrione;   Barbitursaeure;   Malonylharnstoff;   Malonylurea;   pyrimidine-2,4,6(1H,3H,5H)-trione
 alt_id: CHEBI:22692;   CHEBI:2993
 xref: CAS:67-52-7;   Gmelin:101571;   HMDB:HMDB0041833
 xref_mesh: MESH:C032232
 xref: Reaxys:120502;   kegg.compound:C00813;   pubmed:22139480;   pubmed:23038042;   pubmed:23915243;   pubmed:3654008;   wikipedia.en:Barbituric_acid
 chemrof_formula: C4H4N2O3
 chemrof_inchikey: HNYOPLTXPVRDBG-UHFFFAOYSA-N
 chemrof_inchi: InChI=1S/C4H4N2O3/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)
 chemrof_smiles: O=C1CC(=O)NC(=O)N1
 cyclic_relationship: is_conjugate_acid_of CHEBI:29745;   is_conjugate_acid_of CHEBI:57718;   is_conjugate_acid_of CHEBI:77938


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barbituric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maob monoamine oxidase B decreases activity EXP barbituric acid analog results in decreased activity of MAOB protein CTD PMID:24300193 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        xenobiotic 19528
          barbituric acid 1
Path 2
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  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                organic heterocyclic compound 19381
                                  organic heteromonocyclic compound 18004
                                    diazines 13662
                                      pyrimidines 13531
                                        pyrimidone 5091
                                          barbiturates 4651
                                            barbituric acid 1
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