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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:succinic semialdehyde
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Accession:CHEBI:16265 term browser browse the term
Definition:An aldehydic acid that has formula C4H6O3.
Synonyms:exact_synonym: 4-oxobutanoic acid
 related_synonym: 3-formylpropanoic acid;   3-formylpropionic acid;   4-Oxobutanoate;   Formula=C4H6O3;   InChI=1S/C4H6O3/c5-3-1-2-4(6)7/h3H,1-2H2,(H,6,7);   InChIKey=UIUJIQZEACWQSV-UHFFFAOYSA-N;   SMILES=[H]C(=O)CCC(O)=O;   Succinate semialdehyde;   beta-formylpropionic acid;   semialdehyde succinique;   succinaldehydic acid;   succinic acid semialdehyde
 alt_id: CHEBI:15126;   CHEBI:26804;   CHEBI:9305
 xref: Beilstein:1745187;   CAS:692-29-5;   KEGG:C00232;   KNApSAcK:C00019682
 xref_mesh: MESH:C009338
 xref: UM-BBD_compID:c0311
 cyclic_relationship: is_conjugate_acid_of CHEBI:57706


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succinic semialdehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of succinic semialdehyde CTD PMID:10510318 PMID:21276435 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction
affects reduction		 ISO AKR7A2 protein results in increased reduction of succinic semialdehyde
succinic semialdehyde affects the reduction of AKR7A5 protein		 CTD PMID:10510318 PMID:12604212 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects metabolic processing EXP AKR7A3 protein affects the metabolism of succinic semialdehyde CTD PMID:15019089 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases metabolic processing EXP ALDH5A1 protein results in increased metabolism of succinic semialdehyde CTD PMID:17010440 PMID:18926807 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        solvent 17252
          formic acid 9096
            formyl group 9053
              aldehyde 9053
                aldehydic acid 23
                  succinic semialdehyde 4
                    ethyl 4-oxobutanoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbon oxoacid 18681
                                    carboxylic acid 18678
                                      carboacyl group 17728
                                        univalent carboacyl group 17728
                                          formyl group 9053
                                            aldehyde 9053
                                              aldehydic acid 23
                                                succinic semialdehyde 4
                                                  ethyl 4-oxobutanoate 0
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