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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:UDP-N-acetyl-alpha-D-glucosamine
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Accession:CHEBI:16264 term browser browse the term
Definition:A UDP-amino sugar having N-acetyl-alpha-D-glucosamine as the amino sugar component.
Synonyms:exact_synonym: uridine 5'-[3-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl) dihydrogen diphosphate]
 related_synonym: (2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name);   Formula=C17H27N3O17P2;   InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/t7-,8-,10-,11-,12-,13-,14-,15-,16-/m1/s1;   InChIKey=LFTYTUAZOPRMMI-CFRASDGPSA-N;   SMILES=CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O;   UDP-GlcNAc;   UDP-N-acetyl-D-glucosamine;   UDP-N-acetylglucosamine;   URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
 alt_id: CHEBI:13456;   CHEBI:13473;   CHEBI:13475;   CHEBI:13476;   CHEBI:22115;   CHEBI:46243;   CHEBI:9823
 xref: CAS:528-04-1;   HMDB:HMDB0000290;   KEGG:C00043;   KEGG:G10610;   KNApSAcK:C00019358
 xref_mesh: MESH:D014537
 xref: PDBeChem:UD1;   PMID:21627825;   PMID:22825354;   PMID:22887999;   PMID:22901411;   Reaxys:78982
 cyclic_relationship: is_conjugate_acid_of CHEBI:57705


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UDP-N-acetyl-alpha-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance		 ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate N-Acetylglucosamine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          metabolite 19562
            prokaryotic metabolite 18618
              bacterial metabolite 18592
                Escherichia coli metabolite 18527
                  UDP-N-acetyl-alpha-D-glucosamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      chalcogen 19598
                        oxygen atom 19570
                          oxygen molecular entity 19570
                            hydroxides 19374
                              oxoacid 18808
                                pnictogen oxoacid 14987
                                  phosphorus oxoacid 14587
                                    phosphoric acids 13935
                                      phosphoric acid 13935
                                        phosphoric acid derivative 13817
                                          phosphate 13843
                                            organic phosphate 13816
                                              carbohydrate phosphate 1964
                                                phospho sugar 1809
                                                  aldose phosphate 1714
                                                    aldopentose phosphate 1703
                                                      ribose phosphate 1793
                                                        ribonucleotide 1755
                                                          ribonucleoside 5'-phosphate 650
                                                            ribonucleoside 5'-diphosphate 116
                                                              pyrimidine ribonucleoside 5'-diphosphate 23
                                                                UDP 18
                                                                  UDP-sugar 10
                                                                    UDP-amino sugar 2
                                                                      UDP-alpha-D-glucosamine 1
                                                                        UDP-D-glucosamine 1
                                                                          UDP-N-acetyl-alpha-D-glucosamine 1
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