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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-(trimethylammonio)butanoate
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Accession:CHEBI:16244 term browser browse the term
Definition:An amino-acid betaine gamma-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups.
Synonyms:related_synonym: 3-Dehydroxycarnitine;   4-(N-trimethylamino)butyrate;   4-(trimethylamino)butanoate;   4-butyrobetaine;   Actinine;   Formula=C7H15NO2;   InChI=1S/C7H15NO2/c1-8(2,3)6-4-5-7(9)10/h4-6H2,1-3H3;   InChIKey=JHPNVNIEXXLNTR-UHFFFAOYSA-N;   SMILES=C[N+](C)(C)CCCC([O-])=O;   butyrobetaine;   deoxycarnitine;   gamma-Butyrobetain;   gamma-butyrobetaine
 alt_id: CHEBI:12047;   CHEBI:20484
 xref: Beilstein:3538300;   CAS:407-64-7;   ECMDB:ECMDB21336;   HMDB:HMDB0006831
 xref_mesh: MESH:C002889
 xref: MetaCyc:GAMMA-BUTYROBETAINE;   PMID:3148329;   PMID:398096;   Reaxys:3538300
 cyclic_relationship: is_conjugate_base_of CHEBI:1941


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4-(trimethylammonio)butanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO [BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine CTD PMID:21439360 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance		 ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        biochemical role 19569
          metabolite 19577
            butyrate 114
              gamma-aminobutyrate 2
                4-(trimethylammonio)butanoate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    main group molecular entity 19855
                      s-block molecular entity 19666
                        hydrogen molecular entity 19668
                          hydrides 19176
                            inorganic hydride 18187
                              pnictogen hydride 18177
                                nitrogen hydride 18090
                                  ammonium 8321
                                    ammonium ion derivative 8306
                                      quaternary ammonium ion 5300
                                        quaternary nitrogen compound 881
                                          ammonium betaine 370
                                            amino-acid betaine 275
                                              4-(trimethylammonio)butanoate 2
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