CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 3,4-dihydrocoumarin
Accession: CHEBI:16151
browse the term
Definition: A chromanone that is the 3,4-dihydro derivative of coumarin.
Synonyms: exact_synonym: 3,4-dihydro-2H-1-benzopyran-2-one
related_synonym: 1,2-benzodihydropyrone; 2-chromanone; 2-hydroxydihydrocinnamic acid lactone; 3,4-dihydro-2H-chromen-2-one; Dihydrocoumarin; Formula=C9H8O2; InChI=1S/C9H8O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-4H,5-6H2; InChIKey=VMUXSMXIQBNMGZ-UHFFFAOYSA-N; SMILES=O=C1CCc2ccccc2O1; benzodihydropyrone; chroman-2-one; hydrocoumarin; melilotic acid lactone; melilotic lactone; melilotin; melilotol; o-hydroxydihydrocinnamic acid lactone; o-hydroxyhydrocinnamic acid delta-lactone; oxochroman
alt_id: CHEBI:14147; CHEBI:23737; CHEBI:4560
xref: CAS:119-84-6; Gmelin:874678; HMDB:HMDB0036626; KEGG:C02274
xref_mesh: MESH:C026308
xref: MetaCyc:DIHYDROCOUMARIN; PMID:12616288; PMID:16362078; PMID:16769080; Reaxys:4584; UM-BBD_compID:c0397
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Ddit3
DNA-damage inducible transcript 3
affects expression
ISO
3,4-dihydrocoumarin affects the expression of DDIT3 mRNA
CTD
PMID:22016648
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of DNAJA2 mRNA
CTD
PMID:22016648
NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
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Egf
epidermal growth factor
increases expression
ISO
3,4-dihydrocoumarin results in increased expression of EGF mRNA
CTD
PMID:22016648
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Ephx1
epoxide hydrolase 1
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of EPHX1 mRNA
CTD
PMID:22016648
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
increases expression
ISO
3,4-dihydrocoumarin results in increased expression of HSD17B4 mRNA
CTD
PMID:22016648
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of HSP90AB1 mRNA
CTD
PMID:22016648
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
ISO
3,4-dihydrocoumarin results in increased expression of HSPA1A mRNA
CTD
PMID:22016648
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Oat
ornithine aminotransferase
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of OAT mRNA
CTD
PMID:22016648
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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Pck1
phosphoenolpyruvate carboxykinase 1
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of PCK1 mRNA
CTD
PMID:22016648
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pon1
paraoxonase 1
affects metabolic processing
ISO
PON1 SNP affects the metabolism of 3,4-dihydrocoumarin
CTD
PMID:25027835
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Prdx1
peroxiredoxin 1
increases expression
ISO
3,4-dihydrocoumarin results in increased expression of PRDX1 mRNA
CTD
PMID:22016648
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prdx3
peroxiredoxin 3
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of PRDX3 mRNA
CTD
PMID:22016648
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Psmb8
proteasome 20S subunit beta 8
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of PSMB8 mRNA
CTD
PMID:22016648
NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
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Ptpmt1
protein tyrosine phosphatase, mitochondrial 1
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of PTPMT1 mRNA
CTD
PMID:22016648
NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427
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Rbp4
retinol binding protein 4
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of RBP4 mRNA
CTD
PMID:22016648
NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
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Sod1
superoxide dismutase 1
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of SOD1 mRNA
CTD
PMID:22016648
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Timp2
TIMP metallopeptidase inhibitor 2
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of TIMP2 mRNA
CTD
PMID:22016648
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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Tubb5
tubulin, beta 5 class I
decreases expression
ISO
3,4-dihydrocoumarin results in decreased expression of TUBB5 mRNA
CTD
PMID:22016648
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
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