cytosine - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	cytosine	go back to main search page
Accession:	CHEBI:16040	browse the term
Definition:	An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4.
Synonyms:	exact_synonym:	4-aminopyrimidin-2(1H)-one
	related_synonym:	4-amino-2(1H)-pyrimidinone; 4-amino-2-hydroxypyrimidine; C; Cyt; Cytosin; Formula=C4H5N3O; InChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8); InChIKey=OPTASPLRGRRNAP-UHFFFAOYSA-N; SMILES=Nc1cc[nH]c(=O)n1; Zytosin
	alt_id:	CHEBI:14066; CHEBI:23531; CHEBI:4072; CHEBI:41732
	xref:	Beilstein:2637; CAS:71-30-7; Gmelin:82472; HMDB:HMDB0000630; KEGG:C00380; KNApSAcK:C00001498; MetaCyc:CYTOSINE; PDBeChem:CYT; PMID:14253484; PMID:22770225; PMID:7877593; Reaxys:2637; Wikipedia:Cytosine

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Rat (1372) Mouse (1386) Human (1409) Chinchilla (0) Bonobo (0) Dog (1) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (1372)

2'-deoxycytidine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

multiple interactions

Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein]

PMID:9297556 PMID:9403342

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

deoxycytidine kinase

affects binding

Deoxycytidine binds to DCK protein

NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247

G

solute carrier family 28 member 1

increases transport

SLC28A1 protein results in increased transport of Deoxycytidine

NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464

3'-CMP

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CDP-diacylglycerol--inositol 3-phosphatidyltransferase

multiple interactions

[delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate

NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408

3,N(4)-ethenocytosine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

methyl-CpG binding domain 4 DNA glycosylase

affects glycosylation

MBD4 protein affects the glycosylation of 3,N(4)-ethenocytosine

NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982

G

thymine-DNA glycosylase

increases metabolic processing

TDG protein results in increased metabolism of 3,N(4)-ethenocytosine

NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567

5-(hydroxymethyl)cytosine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATM serine/threonine kinase

decreases methylation

5-hydroxymethylcytosine results in decreased methylation of ATM gene

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

cytidine monophospho-N-acetylneuraminic acid hydroxylase

multiple interactions

[bisphenol A results in decreased methylation of CMAH intron] which results in decreased abundance of 5-hydroxymethylcytosine

NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275

G

DNA methyltransferase 1

multiple interactions

DNMT1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; DNMT1 protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine]

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

multiple interactions

DNMT3A protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; DNMT3A protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine]

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

estrogen receptor 1

decreases abundance
multiple interactions

ESR1 protein results in decreased abundance of 5-hydroxymethylcytosine
ESR1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; ESR1 protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine]

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

ferritin light chain 1

multiple interactions

[Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of FTL mRNA

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

[hydroquinone affects the methylation of GCLC promoter] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

GNAS complex locus

multiple interactions

[bisphenol A results in increased methylation of GNAS intron] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

growth factor receptor bound protein 10

multiple interactions

[bisphenol A results in increased methylation of GRB10 intron] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

isocitrate dehydrogenase (NADP(+)) 2

decreases abundance

IDH2 protein mutant form results in decreased abundance of 5-hydroxymethylcytosine

NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025

G

potassium voltage-gated channel subfamily Q member 1

multiple interactions

[bisphenol A results in decreased methylation of KCNQ1 intron] which results in decreased abundance of 5-hydroxymethylcytosine

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

G

KLF transcription factor 14

multiple interactions

[bisphenol A results in decreased methylation of KLF14 exon] which results in decreased abundance of 5-hydroxymethylcytosine

NCBI chr 4:59,554,011...59,556,933
Ensembl chr 4:59,554,011...59,556,933

G

phosphodiesterase 10A

multiple interactions

[bisphenol A results in increased methylation of PDE10A intron] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563

G

phosphodiesterase 4D

multiple interactions

[bisphenol A results in increased methylation of PDE4D exon] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884

G

PLAG1 like zinc finger 1

multiple interactions

[bisphenol A results in increased methylation of PLAGL1 exon] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228

G

protein phosphatase 1, regulatory subunit 9A

multiple interactions

[bisphenol A results in decreased methylation of PPP1R9A intron] which results in decreased abundance of 5-hydroxymethylcytosine

NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907

G

stratifin

multiple interactions

[hydroquinone affects the methylation of SFN promoter] which results in increased abundance of 5-hydroxymethylcytosine

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

tet methylcytosine dioxygenase 1

multiple interactions

TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine]

NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052

G

tet methylcytosine dioxygenase 2

multiple interactions
increases abundance

TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine]
TET2 protein results in increased abundance of 5-hydroxymethylcytosine
bisphenol A promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; bisphenol S promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine]

PMID:24214992 PMID:32105160

NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534

G

ubiquitin C

multiple interactions

[Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of UBC mRNA

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

5-fluorocytidine

term browser

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Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytidine deaminase

increases metabolic processing

CDA protein results in increased metabolism of 5-fluorocytidine

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

5-methylcytosine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

[hydroquinone affects the methylation of GCLC promoter] which results in decreased abundance of 5-Methylcytosine

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

stratifin

multiple interactions

[hydroquinone affects the methylation of SFN promoter] which results in decreased abundance of 5-Methylcytosine

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

tet methylcytosine dioxygenase 1

multiple interactions

TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine]; TET1 protein affects the reaction [Chloranil results in increased oxidation of 5-Methylcytosine]

NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052

G

tet methylcytosine dioxygenase 2

multiple interactions

TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine]; TET2 protein affects the reaction [Chloranil results in increased oxidation of 5-Methylcytosine]

NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534

G

WD repeat containing, antisense to TP53

multiple interactions

[Pesticides results in increased methylation of WRAP53 gene] which results in increased abundance of 5-Methylcytosine

NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929

capecitabine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 7

decreases response to substance

ABCB7 protein results in decreased susceptibility to Capecitabine

NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858

G

acetyl-CoA acyltransferase 1A

increases response to substance

ACAA1 protein results in increased susceptibility to Capecitabine

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

1-acylglycerol-3-phosphate O-acyltransferase 2

increases response to substance

AGPAT2 protein results in increased susceptibility to Capecitabine

NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371

G

anterior gradient 2, protein disulphide isomerase family member

increases response to substance

AGR2 protein results in increased susceptibility to Capecitabine

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

G

aldo-keto reductase family 1 member B1

decreases response to substance

AKR1B1 protein results in decreased susceptibility to Capecitabine

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1, member C3

increases response to substance

AKR1C3 protein results in increased susceptibility to Capecitabine

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

AKT serine/threonine kinase 1

multiple interactions

capecitabine decreases expression and phosphorylation of AKT1 protein in colon

RGD

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aquaporin 8

increases expression

Capecitabine results in increased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

ADP-ribosylation factor like GTPase 4D

decreases response to substance

ARL4D protein results in decreased susceptibility to Capecitabine

NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

increases expression

Capecitabine results in increased expression of ATP12A mRNA

NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229

G

Axl receptor tyrosine kinase

decreases response to substance

AXL protein results in decreased susceptibility to Capecitabine

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

complement C3

decreases expression

Capecitabine results in decreased expression of C3 mRNA

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

calnexin

multiple interactions

CANX results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

catalase

decreases activity

Capecitabine results in decreased activity of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

C-C motif chemokine ligand 19

decreases expression

Capecitabine results in decreased expression of CCL19 mRNA

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

G

C-C motif chemokine ligand 21

decreases expression

Capecitabine results in decreased expression of CCL21 mRNA

NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686

G

cellular communication network factor 1

decreases response to substance
decreases expression

CCN1 protein results in decreased susceptibility to Capecitabine
Capecitabine results in decreased expression of CCN1 mRNA

PMID:16734730 PMID:36183961

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cyclin-dependent kinase inhibitor 2A

decreases expression

Capecitabine results in decreased expression of CDKN2A protein

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

carboxylesterase 1D

multiple interactions

CES1 protein results in increased hydrolysis of and results in increased activity of Capecitabine

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 2H

multiple interactions
increases response to substance

CES2 protein results in increased hydrolysis of and results in increased activity of Capecitabine
CES2 gene polymorphism results in increased susceptibility to Capecitabine

PMID:15687373 PMID:18473752

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

calcium and integrin binding 1

increases response to substance

CIB1 protein results in increased susceptibility to Capecitabine

NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423

G

claudin 3

increases response to substance

CLDN3 protein results in increased susceptibility to Capecitabine

NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001

G

C-X-C motif chemokine ligand 12

decreases expression

Capecitabine decreases expression of CXCL12 protein in liver and colon

RGD

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 3

increases expression

Capecitabine results in increased expression of CXCL1

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine receptor 4

decreases expression

Capecitabine decreases expression of CXCR4 protein in liver and colon

RGD

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

dihydropyrimidine dehydrogenase

increases expression
decreases response to substance
affects response to substance

Capecitabine results in increased expression of DPYD mRNA
DPYD protein results in decreased susceptibility to Capecitabine
DPYD protein affects the susceptibility to Capecitabine

PMID:16734730 PMID:17611699 PMID:18846242

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

dermatan sulfate epimerase

decreases response to substance

DSE protein results in decreased susceptibility to Capecitabine

NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992

G

EGFR pathway substrate 8, signaling adaptor

increases response to substance

EPS8 protein results in increased susceptibility to Capecitabine

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

erb-b2 receptor tyrosine kinase 3

increases response to substance

ERBB3 protein results in increased susceptibility to Capecitabine

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

Fc receptor-like A

decreases expression

Capecitabine results in decreased expression of FCRLA mRNA

NCBI chr13:83,160,453...83,170,170
Ensembl chr13:83,160,398...83,170,762

G

four and a half LIM domains 1

decreases response to substance

FHL1 protein results in decreased susceptibility to Capecitabine

NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928

G

FLII, actin remodeling protein

decreases response to substance

FLII protein results in decreased susceptibility to Capecitabine

NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970

G

alpha-L-fucosidase 1

increases response to substance

FUCA1 protein results in increased susceptibility to Capecitabine

NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972

G

glutamine amidotransferase class 1 domain containing 3A

increases expression

Capecitabine results in increased expression of GATD3A mRNA

NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885

G

glutathione peroxidase 1

decreases activity

Capecitabine results in decreased activity of GPX1 protein

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

hemoglobin alpha, adult chain 2

decreases expression

Capecitabine results in decreased expression of HBA1 mRNA

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin alpha, adult chain 3

decreases expression

Capecitabine results in decreased expression of HBA2 mRNA

NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481

G

hemoglobin subunit beta

decreases expression

Capecitabine results in decreased expression of HBB mRNA

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

HDGF like 3

decreases response to substance

HDGFL3 protein results in decreased susceptibility to Capecitabine

NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719

G

hypoxia inducible factor 1 subunit alpha

decreases response to substance
ameliorates

HIF1A protein results in decreased susceptibility to Capecitabine
capecitabine decreases expression of HIF1A protein in colon

CTD
RGD

PMID:16734730 PMID:30789971

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

HRas proto-oncogene, GTPase

decreases response to substance

HRAS protein results in decreased susceptibility to Capecitabine

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

interleukin 17 receptor B

increases response to substance

IL17RB protein results in increased susceptibility to Capecitabine

NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125

G

interleukin 1 receptor type 2

increases response to substance

IL1R2 protein results in increased susceptibility to Capecitabine

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

G

interleukin 6

increases expression
multiple interactions

Capecitabine metabolite results in increased expression of IL6 mRNA; Capecitabine results in increased expression of IL6
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Capecitabine metabolite results in increased expression of IL6 mRNA]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

JunB proto-oncogene, AP-1 transcription factor subunit

multiple interactions

JUNB results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

galectin 4

increases response to substance

LGALS4 protein results in increased susceptibility to Capecitabine

NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481

G

leucine rich repeat containing 15

decreases expression

Capecitabine results in decreased expression of LRRC15 mRNA

NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267

G

MDM4 regulator of p53

multiple interactions

MDM4 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]

NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226

G

matrix metallopeptidase 2

multiple interactions
decreases expression

MMP2 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]
capecitabine decreases expression of MMP2 protein in colon

CTD
RGD

PMID:18678097 PMID:30789971

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

MRE11 homolog, double strand break repair nuclease

decreases response to substance

MRE11 protein results in decreased susceptibility to Capecitabine

NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279

G

membrane spanning 4-domains A1

decreases expression

Capecitabine results in decreased expression of MS4A1 mRNA

NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512

G

MYB proto-oncogene, transcription factor

increases response to substance

MYB protein results in increased susceptibility to Capecitabine

NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057

G

myelin regulatory factor

increases response to substance

MYRF protein results in increased susceptibility to Capecitabine

NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157

G

nuclear receptor subfamily 4, group A, member 1

decreases expression

Capecitabine results in decreased expression of NR4A1 mRNA

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297

G

nuclear receptor subfamily 4, group A, member 2

decreases expression

Capecitabine results in decreased expression of NR4A2 mRNA

NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877

G

paired box 5

decreases expression

Capecitabine results in decreased expression of PAX5 mRNA

NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

multiple interactions

capecitabine decreases expression and phosphorylation of PIK3CB protein in colon

RGD

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

G

polycystin 2, transient receptor potential cation channel

decreases response to substance

PKD2 protein results in decreased susceptibility to Capecitabine

NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825

G

plakophilin 2

increases response to substance

PKP2 protein results in increased susceptibility to Capecitabine

NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730

G

phospholipase C, epsilon 1

increases response to substance

PLCE1 protein results in increased susceptibility to Capecitabine

NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438

G

inorganic pyrophosphatase 1

increases response to substance

PPA1 protein results in increased susceptibility to Capecitabine

NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215

G

protein kinase cAMP-activated catalytic subunit beta

decreases response to substance

PRKACB protein results in decreased susceptibility to Capecitabine

NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198

G

prostaglandin-endoperoxide synthase 2

decreases expression

Capecitabine results in decreased expression of PTGS2 protein
Capecitabine metabolite results in decreased expression of PTGS2

PMID:17904787 PMID:35147423

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine phosphatase, non-receptor type 13

decreases response to substance

PTPN13 protein results in decreased susceptibility to Capecitabine

NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563

G

glycogen phosphorylase B

increases response to substance

PYGB protein results in increased susceptibility to Capecitabine

NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553

G

Rab40b, member RAS oncogene family

increases response to substance

RAB40B protein results in increased susceptibility to Capecitabine

NCBI chr10:106,631,514...106,659,090
Ensembl chr10:106,631,514...106,659,090

G

RB transcriptional corepressor 1

multiple interactions

RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RB binding protein 4, chromatin remodeling factor

multiple interactions

RBBP4 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]

NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284

G

replication protein A1

decreases response to substance

RPA1 protein results in decreased susceptibility to Capecitabine

NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949

G

RAS related 2

decreases response to substance

RRAS2 protein results in decreased susceptibility to Capecitabine

NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111

G

RT1 class II, locus Ba

decreases expression

Capecitabine results in decreased expression of HLA-DQA1 mRNA

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

salt-inducible kinase 1

decreases expression

Capecitabine results in decreased expression of SIK1 mRNA

NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991

G

solute carrier family 26 member 3

increases expression

Capecitabine results in increased expression of SLC26A3 mRNA

NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772

G

solute carrier organic anion transporter family, member 2b1

multiple interactions

Capecitabine inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]

NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353

G

superoxide dismutase 1

decreases activity

Capecitabine results in decreased activity of SOD1 protein

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

stress-induced phosphoprotein 1

decreases response to substance

STIP1 protein results in decreased susceptibility to Capecitabine

NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476

G

transcription factor 7 like 2

multiple interactions

TCF7L2 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]

NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967

G

TEA domain transcription factor 1

decreases response to substance

TEAD1 protein results in decreased susceptibility to Capecitabine

NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369

G

trefoil factor 1

increases response to substance

TFF1 protein results in increased susceptibility to Capecitabine

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

tripartite motif containing 15

increases response to substance

TRIM15 protein results in increased susceptibility to Capecitabine

NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249

G

tripartite motif-containing 31

increases expression

Capecitabine results in increased expression of TRIM31 mRNA

NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494

G

thymidylate synthetase

affects expression
decreases response to substance
multiple interactions

Capecitabine affects the expression of TYMS mRNA
TYMS protein results in decreased susceptibility to Capecitabine
[TYMS enhancer polymorphism co-treated with VEGFA gene SNP] affects the susceptibility to [Capecitabine co-treated with oxaliplatin]

PMID:16438929 PMID:16734730 PMID:21048041

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

uroplakin 3A

increases expression

Capecitabine results in increased expression of UPK3A mRNA

NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:116,134,874...116,139,948

G

vascular endothelial growth factor A

multiple interactions
decreases expression

[TYMS enhancer polymorphism co-treated with VEGFA gene SNP] affects the susceptibility to [Capecitabine co-treated with oxaliplatin]
capecitabine decreases expression of VEGFA protein in blood serum and colon

CTD
RGD

PMID:21048041 PMID:30789971

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

zinc finger protein 706

increases response to substance

ZNF706 protein results in increased susceptibility to Capecitabine

NCBI chr 7:68,167,496...68,174,121
Ensembl chr 7:68,166,323...68,174,148

CDP-choline

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

decreases expression

Cytidine Diphosphate Choline results in decreased expression of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

intercellular adhesion molecule 1

decreases expression

Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

neutral cholesterol ester hydrolase 1

multiple interactions

NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor]

NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588

G

poly (ADP-ribose) polymerase 1

decreases expression

Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

sirtuin 1

increases expression
multiple interactions

Cytidine Diphosphate Choline results in increased expression of SIRT1 protein
Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

CMP-N-acetyl-beta-neuraminic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytidine monophosphate N-acetylneuraminic acid synthetase

affects abundance

CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid

NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125

CTP

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

multiple interactions

Cytidine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein]

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

amyloid beta precursor protein

increases secretion

Cytidine Triphosphate results in increased secretion of APP protein modified form

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

purinergic receptor P2X 1

affects binding

CTP binds to P2rx1 protein

RGD

NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623

G

purinergic receptor P2X 5

affects transport

CTP affects transport ion flux of P2rx5 receptor

RGD

NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423

cytarabine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

affects response to substance
increases expression

ABCB1 protein affects the susceptibility to Cytarabine
Cytarabine results in increased expression of ABCB1

PMID:11573427 PMID:17852453

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 1

affects response to substance

ABCC1 protein affects the susceptibility to Cytarabine

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

increases expression

Cytarabine results in increased expression of ACAP1 mRNA

NCBI chr10:54,605,323...54,619,472
Ensembl chr10:54,605,323...54,619,472

G

acetylcholinesterase

multiple interactions
increases activity

betanin inhibits the reaction [Cytarabine results in increased activity of ACHE protein]; thymoquinone inhibits the reaction [Cytarabine results in increased activity of ACHE protein]; Vitamin D inhibits the reaction [Cytarabine results in increased activity of ACHE protein]

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

actin, alpha 1, skeletal muscle

increases expression

Cytarabine results in increased expression of ACTA1 mRNA

NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742

G

actin, alpha, cardiac muscle 1

decreases expression

Cytarabine results in decreased expression of ACTC1 mRNA

NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523

G

ADAM metallopeptidase domain 19

decreases expression

Cytarabine results in decreased expression of ADAM19 mRNA

NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

decreases expression

Cytarabine results in decreased expression of ADAMTS1 mRNA

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

ADAM metallopeptidase with thrombospondin type 1 motif, 9

decreases expression

Cytarabine results in decreased expression of ADAMTS9 mRNA

NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929

G

adhesion G protein-coupled receptor B3

increases expression

Cytarabine results in increased expression of ADGRB3 mRNA

NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855

G

adiponectin, C1Q and collagen domain containing

multiple interactions

[2,2-bis(4-glycidyloxyphenyl)propane co-treated with Cytarabine] results in decreased expression of ADIPOQ mRNA

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

actin filament associated protein 1-like 2

decreases expression

Cytarabine results in decreased expression of AFAP1L2 mRNA

NCBI chr 1:255,964,238...256,060,828
Ensembl chr 1:255,964,238...256,060,820

G

Abelson helper integration site 1

increases expression

Cytarabine results in increased expression of AHI1 protein alternative form

NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041

G

AHNAK nucleoprotein

decreases expression

Cytarabine results in decreased expression of AHNAK mRNA

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

allograft inflammatory factor 1-like

increases expression

Cytarabine results in increased expression of AIF1L mRNA

NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023

G

aldo-keto reductase family 1, member B8

decreases expression

Cytarabine results in decreased expression of AKR1B15 mRNA

NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097

G

alpha-kinase 2

decreases expression

Cytarabine results in decreased expression of ALPK2 mRNA

NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258

G

angiopoietin-like 2

decreases expression

Cytarabine results in decreased expression of ANGPTL2 mRNA

NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178

G

ankyrin repeat and sterile alpha motif domain containing 1A

decreases expression

Cytarabine results in decreased expression of ANKS1A mRNA

NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148

G

anoctamin 8

increases expression

Cytarabine results in increased expression of ANO8 mRNA

NCBI chr16:18,163,853...18,173,248
Ensembl chr16:18,163,843...18,173,545

G

annexin A2

decreases expression
increases expression

Cytarabine results in decreased expression of ANXA2 mRNA
Cytarabine results in increased expression of ANXA2 mRNA

PMID:12165291 PMID:21198554

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

annexin A6

decreases expression

Cytarabine results in decreased expression of ANXA6 mRNA

NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433

G

annexin A8

decreases expression

Cytarabine results in decreased expression of ANXA8 mRNA

NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043

G

apelin receptor

decreases expression

Cytarabine results in decreased expression of APLNR mRNA

NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050

G

aquaporin 1

decreases expression

Cytarabine results in decreased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

arginase 2

decreases expression

Cytarabine results in decreased expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 44

decreases expression

Cytarabine results in decreased expression of ARHGAP44 mRNA

NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297

G

Rho GDP dissociation inhibitor beta

decreases expression

Cytarabine results in decreased expression of ARHGDIB mRNA

NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658

G

Rho guanine nucleotide exchange factor 3

decreases expression

Cytarabine results in decreased expression of ARHGEF3 mRNA

NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945

G

ADP-ribosylation factor like GTPase 6 interacting protein 5

increases expression

Cytarabine results in increased expression of ARL6IP5 protein

NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608

G

ADP-ribosyltransferase 4

decreases expression

Cytarabine results in decreased expression of ART4 mRNA

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

ADP-ribosyltransferase 5

decreases expression

Cytarabine results in decreased expression of ART5 mRNA

NCBI chr 1:156,473,362...156,483,324
Ensembl chr 1:156,473,362...156,483,324

G

activating transcription factor 3

decreases expression
increases expression

Cytarabine results in decreased expression of ATF3 mRNA
Cytarabine results in increased expression of ATF3 mRNA

PMID:21198554 PMID:33770205

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

atlastin GTPase 1

increases expression

Cytarabine results in increased expression of ATL1 mRNA

NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204

G

atrophin 1

increases expression

Cytarabine results in increased expression of ATN1 mRNA

NCBI chr 4:157,554,287...157,568,092
Ensembl chr 4:157,551,276...157,568,132

G

ATPase phospholipid transporting 10D (putative)

increases expression

Cytarabine results in increased expression of ATP10D mRNA

NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564

G

ATPase Na+/K+ transporting subunit beta 1

decreases expression

Cytarabine results in decreased expression of ATP1B1 mRNA

NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459

G

ATPase copper transporting beta

decreases expression

Cytarabine results in decreased expression of ATP7B mRNA

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

ATPase phospholipid transporting 8B4 (putative)

decreases expression

Cytarabine results in decreased expression of ATP8B4 mRNA

NCBI chr 3:113,554,979...113,757,635
Ensembl chr 3:113,556,192...113,757,225

G

Axl receptor tyrosine kinase

decreases expression

Cytarabine results in decreased expression of AXL mRNA

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

beta-2 microglobulin

increases expression

Cytarabine results in increased expression of B2M protein

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

beta-1,4-galactosyltransferase 7

decreases expression

Cytarabine results in decreased expression of B4GALT7 mRNA

NCBI chr17:9,018,514...9,027,591
Ensembl chr17:9,018,935...9,027,573

G

BAG cochaperone 3

decreases expression

Cytarabine results in decreased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BAR/IMD domain containing adaptor protein 2 like 1

decreases expression

Cytarabine results in decreased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

BCL2 associated X, apoptosis regulator

increases expression

Cytarabine results in increased expression of BAX mRNA
[Cytarabine results in increased expression of TP53 protein] which results in increased expression of BAX protein; Cytarabine results in increased expression of BAX protein

PMID:10200513 PMID:15203180 PMID:16129037 PMID:17490525

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

affects response to substance

BBC3 protein affects the susceptibility to Cytarabine

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCAR3 adaptor protein, NSP family member

decreases expression

Cytarabine results in decreased expression of BCAR3 mRNA

NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798

G

butyrylcholinesterase

increases activity
multiple interactions

Cytarabine results in increased activity of BCHE protein
betanin inhibits the reaction [Cytarabine results in increased activity of BCHE protein]

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

multiple interactions
increases degradation
decreases expression

[Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]; edelfosine promotes the reaction [Cytarabine results in decreased expression of BCL2 protein]
Cytarabine results in increased degradation of BCL2 protein
Cytarabine results in decreased expression of BCL2 mRNA; Cytarabine results in decreased expression of BCL2 protein

PMID:1450413 PMID:8840993 PMID:9295281 PMID:12853972 PMID:16129037 More...

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

multiple interactions

BCL2L1 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

basic helix-loop-helix family, member e22

increases expression

Cytarabine results in increased expression of BHLHE22 mRNA

NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510

G

BH3 interacting domain death agonist

multiple interactions

[Cytarabine co-treated with TNFSF10 protein] results in increased expression of BID protein

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

bridging integrator 2

increases expression

Cytarabine results in increased expression of BIN2 mRNA

NCBI chr 7:131,742,001...131,768,208
Ensembl chr 7:131,742,002...131,786,285

G

bone morphogenetic protein 4

decreases expression

Cytarabine results in decreased expression of BMP4 mRNA

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bone morphogenetic protein 5

decreases expression

Cytarabine results in decreased expression of BMP5 mRNA

NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925

G

basonuclin zinc finger protein 1

decreases expression

Cytarabine results in decreased expression of BNC1 mRNA

NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333

G

basonuclin zinc finger protein 2

decreases expression

Cytarabine results in decreased expression of BNC2 mRNA

NCBI chr 5:98,679,071...99,016,044
Ensembl chr 5:98,687,410...99,079,426

G

bora, aurora kinase A activator

decreases expression

Cytarabine results in decreased expression of BORA mRNA

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

G

3'(2'), 5'-bisphosphate nucleotidase 2

decreases expression

Cytarabine results in decreased expression of BPNT2 mRNA

NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570

G

BRCA2, DNA repair associated

increases expression

Cytarabine results in increased expression of BRCA2 mRNA

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

BSCL2 lipid droplet biogenesis associated, seipin

increases expression

Cytarabine results in increased expression of BSCL2 mRNA

NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421

G

bone marrow stromal cell antigen 2

decreases expression

Cytarabine results in decreased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

BTG anti-proliferation factor 2

increases expression

Cytarabine results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

C2 calcium-dependent domain containing 2

decreases expression

Cytarabine results in decreased expression of C2CD2 mRNA

NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739

G

complement C3a receptor 1

increases expression

Cytarabine results in increased expression of C3AR1 mRNA

NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701

G

calcium binding protein 39-like

decreases expression

Cytarabine results in decreased expression of CAB39L mRNA

NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545

G

calbindin 1

decreases expression

Cytarabine results in decreased expression of CALB1 protein

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

G

calbindin 2

decreases expression

Cytarabine results in decreased expression of CALB2 mRNA

NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438

G

calcitonin receptor

increases response to substance

CALCR results in increased susceptibility to Cytarabine

NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

increases expression

Cytarabine results in increased expression of CAMK2N1 mRNA

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

G

calpain 1

decreases expression

Cytarabine results in decreased expression of CAPN1 mRNA

NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177

G

carbonic anhydrase 12

decreases expression

Cytarabine results in decreased expression of CA12 mRNA

NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440

G

capping protein regulator and myosin 1 linker 1

decreases expression

Cytarabine results in decreased expression of CARMIL1 mRNA

NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326

G

caspase 3

multiple interactions
increases activity
increases expression

[Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein
Cytarabine results in increased activity of CASP3 protein
Cytarabine results in increased expression of CASP3 protein

PMID:8840993 PMID:12780785 PMID:12781215 PMID:14766721 PMID:22212197 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; Cytarabine promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Cytarabine results in increased expression of and results in increased cleavage of CASP8 protein

PMID:12780785 PMID:18549619 PMID:22010212

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caveolae associated protein 1

decreases expression

Cytarabine results in decreased expression of CAVIN1 mRNA

NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120

G

caveolae associated protein 3

decreases expression

Cytarabine results in decreased expression of CAVIN3 mRNA

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

coiled-coil domain containing 102A

decreases expression

Cytarabine results in decreased expression of CCDC102A mRNA

NCBI chr19:10,102,543...10,118,657
Ensembl chr19:10,103,361...10,118,657

G

coiled-coil domain containing 112

increases expression

Cytarabine results in increased expression of CCDC112 mRNA

NCBI chr18:38,998,139...39,032,329
Ensembl chr18:38,998,139...39,032,329

G

coiled-coil domain containing 15

increases expression

Cytarabine results in increased expression of CCDC15 mRNA

NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919

G

cholecystokinin B receptor

decreases expression

Cytarabine results in decreased expression of CCKBR mRNA

NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881

G

cyclin D3

decreases expression

Cytarabine results in decreased expression of CCND3 mRNA

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E2

increases expression

Cytarabine results in increased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

cyclin G1

increases expression

Cytarabine results in increased expression of CCNG1 mRNA

PMID:14766721 PMID:15203180

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

CD44 molecule

decreases expression

Cytarabine results in decreased expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

CD8 subunit alpha

increases expression

Cytarabine results in increased expression of CD8A mRNA

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

G

CDC42 effector protein 5

decreases expression

Cytarabine results in decreased expression of CDC42EP5 mRNA

NCBI chr 1:70,035,921...70,038,990

G

cell division cycle associated 8

decreases expression

Cytarabine results in decreased expression of CDCA8 mRNA

NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629

G

cadherin 11

decreases expression

Cytarabine results in decreased expression of CDH11 mRNA

NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272

G

cadherin 3

decreases expression

Cytarabine results in decreased expression of CDH3 mRNA

NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084

G

cyclin-dependent kinase 5 regulatory subunit 1

increases expression

Cytarabine results in increased expression of CDK5R1 mRNA

NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression

[fludarabine co-treated with Cytarabine co-treated with Docetaxel] results in increased expression of CDKN1A protein; Caffeine inhibits the reaction [Cytarabine results in increased expression of CDKN1A protein]
Cytarabine results in increased expression of CDKN1A mRNA; Cytarabine results in increased expression of CDKN1A protein

PMID:9703875 PMID:14766721 PMID:15203180 PMID:17977830 PMID:33770205

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

decreases expression

Cytarabine results in decreased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

CCAAT/enhancer binding protein delta

decreases expression

Cytarabine results in decreased expression of CEBPD mRNA

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

G

CUGBP, Elav-like family member 3

increases expression

Cytarabine results in increased expression of CELF3 mRNA

NCBI chr 2:182,116,034...182,130,163
Ensembl chr 2:182,116,073...182,130,163

G

cell migration inducing hyaluronidase 1

decreases expression

Cytarabine results in decreased expression of CEMIP mRNA

NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415

G

choline O-acetyltransferase

increases activity

Cytarabine results in increased activity of CHAT protein

NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093

G

chimerin 1

decreases expression

Cytarabine results in decreased expression of CHN1 mRNA

NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

Cytarabine results in decreased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

creatine kinase B

increases expression

Cytarabine results in increased expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

CDC28 protein kinase regulatory subunit 2

decreases expression

Cytarabine results in decreased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

claudin 15

decreases expression

Cytarabine results in decreased expression of CLDN15 mRNA

NCBI chr12:19,698,167...19,708,419
Ensembl chr12:19,698,337...19,706,819

G

C-type lectin domain family 1, member B

decreases expression

Cytarabine results in decreased expression of CLEC1B mRNA

NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291

G

cornichon family AMPA receptor auxiliary protein 2

increases expression

Cytarabine results in increased expression of CNIH2 mRNA

NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089

G

cannabinoid receptor 1

increases expression

Cytarabine results in increased expression of CNR1 mRNA

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

ciliary neurotrophic factor receptor

increases expression

Cytarabine results in increased expression of CNTFR mRNA

NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392

G

centriolin

increases expression

Cytarabine results in increased expression of CNTRL mRNA

NCBI chr 3:18,428,147...18,500,362
Ensembl chr 3:18,428,103...18,500,380

G

cordon-bleu WH2 repeat protein-like 1

decreases expression

Cytarabine results in decreased expression of COBLL1 mRNA

NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194

G

collagen type XIII alpha 1 chain

decreases expression

Cytarabine results in decreased expression of COL13A1 mRNA

NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032

G

collagen type XVIII alpha 1 chain

decreases expression

Cytarabine results in decreased expression of COL18A1 mRNA

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 1 chain

decreases expression

Cytarabine results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

decreases expression

Cytarabine results in decreased expression of COL1A2 mRNA

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

decreases expression

Cytarabine results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

collagen type V alpha 1 chain

decreases expression

Cytarabine results in decreased expression of COL5A1 mRNA

NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588

G

collagen type V alpha 2 chain

decreases expression

Cytarabine results in decreased expression of COL5A2 mRNA

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

collagen type VI alpha 2 chain

decreases expression

Cytarabine results in decreased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen type VI alpha 3 chain

decreases expression

Cytarabine results in decreased expression of COL6A3 mRNA

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

collagen type IX alpha 1 chain

increases expression

Cytarabine results in increased expression of COL9A1 mRNA

NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213

G

collectin sub-family member 12

decreases expression

Cytarabine results in decreased expression of COLEC12 mRNA

NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618

G

carboxypeptidase Z

decreases expression

Cytarabine results in decreased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

cellular retinoic acid binding protein 1

increases expression

Cytarabine results in increased expression of CRABP1 mRNA

NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression

Cytarabine results in decreased expression of CRISPLD2 mRNA

NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465

G

cartilage associated protein

decreases expression

Cytarabine results in decreased expression of CRTAP mRNA

NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631

G

crystallin, alpha B

decreases expression

Cytarabine results in decreased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

casein kinase 1, delta

decreases expression

Cytarabine results in decreased expression of CSNK1D mRNA

NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614

G

cysteine and serine rich nuclear protein 1

decreases expression

Cytarabine results in decreased expression of AXUD1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cathepsin H

decreases expression

Cytarabine results in decreased expression of CTSH mRNA

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

G

cathepsin L

decreases expression

Cytarabine results in decreased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

C-X-C motif chemokine receptor 4

increases expression

Cytarabine results in increased expression of CXCR4 mRNA

PMID:19194470 PMID:21198554

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

cytochrome b5 type A

decreases expression

Cytarabine results in decreased expression of CYB5A mRNA

NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome b5 domain containing 1

decreases expression

Cytarabine results in decreased expression of CYB5D1 mRNA

NCBI chr10:54,113,428...54,117,744
Ensembl chr10:54,113,438...54,117,911

G

cytochrome b5 reductase 2

decreases expression

Cytarabine results in decreased expression of CYB5R2 mRNA

NCBI chr 1:161,655,862...161,664,359
Ensembl chr 1:161,655,864...161,664,097

G

cytochrome b-245 alpha chain

decreases expression

Cytarabine results in decreased expression of CYBA mRNA

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome P450, family 27, subfamily a, polypeptide 1

decreases expression

Cytarabine results in decreased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 4, subfamily x, polypeptide 1

decreases expression

Cytarabine results in decreased expression of CYP4X1 mRNA

NCBI chr 5:128,651,681...128,683,338
Ensembl chr 5:128,651,776...128,682,779

G

cytohesin 1

increases expression

Cytarabine results in increased expression of CYTH1 mRNA

NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760

G

DAB adaptor protein 2

decreases expression

Cytarabine results in decreased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

DALR anticodon binding domain containing 3

decreases expression

Cytarabine results in decreased expression of DALRD3 mRNA

NCBI chr 8:109,264,100...109,268,560
Ensembl chr 8:109,265,676...109,268,568

G

drebrin 1

decreases expression

Cytarabine results in decreased expression of DBN1 mRNA

NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984

G

deoxycytidine kinase

affects binding
decreases response to substance

Cytarabine binds to DCK protein
Cytarabine binds to Dck protein
DCK gene polymorphism results in decreased susceptibility to Cytarabine

CTD
RGD

PMID:1318170 PMID:18381442 PMID:7532033

NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247

G

decorin

decreases expression

Cytarabine results in decreased expression of DCN mRNA

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

discoidin domain receptor tyrosine kinase 2

decreases expression

Cytarabine results in decreased expression of DDR2 mRNA

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

DENN domain containing 1A

increases expression

Cytarabine results in increased expression of DENND1A mRNA

NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062

G

DEP domain containing MTOR-interacting protein

decreases expression

Cytarabine results in decreased expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

24-dehydrocholesterol reductase

decreases expression

Cytarabine results in decreased expression of DHCR24 mRNA

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

dihydrofolate reductase

increases expression

Cytarabine results in increased expression of DHFR mRNA

NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713

G

dispatched RND transporter family member 3

increases expression

Cytarabine results in increased expression of DISP3 mRNA

NCBI chr 5:158,672,015...158,720,806
Ensembl chr 5:158,672,015...158,720,806

G

dynein, axonemal, heavy chain 2

decreases expression

Cytarabine results in decreased expression of DNAH2 mRNA

NCBI chr10:54,142,648...54,268,901
Ensembl chr10:54,142,737...54,267,298

G

docking protein 4

decreases expression

Cytarabine results in decreased expression of DOK4 mRNA

NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203

G

desmocollin 2

decreases expression

Cytarabine results in decreased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

desmocollin 3

decreases expression

Cytarabine results in decreased expression of DSC3 mRNA

NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797

G

dual specificity phosphatase 4

decreases expression

Cytarabine results in decreased expression of DUSP4 mRNA

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

E2F transcription factor 8

increases expression

Cytarabine results in increased expression of E2F8 mRNA

NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098

G

endothelin 1

multiple interactions

EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
EDN1 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

eukaryotic translation elongation factor 2

decreases expression

Cytarabine results in decreased expression of EEF2 mRNA

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

EGF containing fibulin extracellular matrix protein 2

decreases expression

Cytarabine results in decreased expression of EFEMP2 mRNA

NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414

G

EF-hand domain family, member D1

decreases expression

Cytarabine results in decreased expression of EFHD1 mRNA

NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917

G

ephrin A1

decreases expression

Cytarabine results in decreased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

EGF-like-domain, multiple 6

decreases expression

Cytarabine results in decreased expression of EGFL6 mRNA

NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044

G

EGF-like, fibronectin type III and laminin G domains

decreases expression

Cytarabine results in decreased expression of EGFLAM mRNA

NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298

G

eukaryotic translation initiation factor 4H

decreases expression

Cytarabine results in decreased expression of EIF4H mRNA

NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876

G

enolase 3

decreases expression

Cytarabine results in decreased expression of ENO3 mRNA

NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921

G

ectonucleoside triphosphate diphosphohydrolase 1

increases expression

Cytarabine results in increased expression of ENTPD1 mRNA

NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317

G

exo/endonuclease G

decreases expression

Cytarabine results in decreased expression of EXOG mRNA

NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672

G

exostosin glycosyltransferase 2

decreases expression

Cytarabine results in decreased expression of EXT2 mRNA

NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059

G

ezrin

decreases expression

Cytarabine results in decreased expression of EZR mRNA

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor II, thrombin

affects expression

Cytarabine affects the expression of F2 protein

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

fatty acid binding protein 7

increases expression

Cytarabine results in increased expression of FABP7 mRNA

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

FAM111 trypsin like peptidase A

increases expression

Cytarabine results in increased expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

Fas cell surface death receptor

increases expression

Cytarabine results in increased expression of FAS mRNA

PMID:14766721 PMID:15203180 PMID:33770205

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

fibulin 1

decreases expression

Cytarabine results in decreased expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

F-box protein 2

decreases expression

Cytarabine results in decreased expression of FBXO2 mRNA

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

G

Fc gamma receptor 2A

increases expression

Cytarabine results in increased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

filamin C

decreases expression

Cytarabine results in decreased expression of FLNC mRNA

NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844

G

fibronectin leucine rich transmembrane protein 2

decreases expression

Cytarabine results in decreased expression of FLRT2 mRNA

NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

Cytarabine results in decreased expression of FMO1 mRNA

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

flavin containing dimethylaniline monoxygenase 4

decreases expression

Cytarabine results in decreased expression of FMO4 mRNA

NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874

G

frizzled-related protein

decreases expression

Cytarabine results in decreased expression of FRZB mRNA

NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208

G

fibrous sheath interacting protein 1

increases expression

Cytarabine results in increased expression of FSIP1 mRNA

NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167

G

FYN binding protein 2

decreases expression

Cytarabine results in decreased expression of FYB2 mRNA

NCBI chr 5:119,677,116...119,800,911
Ensembl chr 5:119,677,204...119,800,910

G

FYN proto-oncogene, Src family tyrosine kinase

increases expression

Cytarabine results in increased expression of FYN mRNA

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

G

GABA type A receptor associated protein like 1

decreases expression

Cytarabine results in decreased expression of GABARAPL1 mRNA

NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450

G

gamma-aminobutyric acid type A receptor subunit pi

increases expression

Cytarabine results in increased expression of GABRP mRNA

NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516

G

growth arrest and DNA-damage-inducible, alpha

increases expression

Cytarabine results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 10

decreases expression

Cytarabine results in decreased expression of GALNT10 mRNA

NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013

G

growth associated protein 43

increases expression

Cytarabine results in increased expression of GAP43 mRNA

NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045

G

glyceraldehyde-3-phosphate dehydrogenase

decreases activity
affects localization
increases response to substance

Cytarabine results in decreased activity of GAPDH protein
Cytarabine affects the localization of GAPDH protein
GAPDH protein results in increased susceptibility to Cytarabine

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

GATA binding protein 5

decreases expression

Cytarabine results in decreased expression of GATA5 mRNA

NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751

G

guanylate binding protein 4

decreases expression

Cytarabine results in decreased expression of GBP4 mRNA

NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879

G

grancalcin

decreases expression

Cytarabine results in decreased expression of GCA mRNA

NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581

G

glucosaminyl (N-acetyl) transferase 2

decreases expression

Cytarabine results in decreased expression of GCNT2 mRNA

NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611

G

growth hormone receptor

decreases expression

Cytarabine results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

glutaminase

decreases expression

Cytarabine results in decreased expression of GLS mRNA

NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900

G

G protein subunit beta 3

decreases expression

Cytarabine results in decreased expression of GNB3 mRNA

NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173

G

G protein-coupled estrogen receptor 1

decreases expression

Cytarabine results in decreased expression of GPER1 mRNA

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glycoprotein m6a

increases expression

Cytarabine results in increased expression of GPM6A mRNA

NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475

G

G protein-coupled receptor 19

increases expression

Cytarabine results in increased expression of GPR19 mRNA

NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036

G

G protein-coupled receptor 83

decreases expression

Cytarabine results in decreased expression of GPR83 mRNA

NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028

G

G protein-coupled receptor, class C, group 5, member C

decreases expression

Cytarabine results in decreased expression of GPRC5C mRNA

NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926

G

glutamate ionotropic receptor AMPA type subunit 2

increases expression

Cytarabine results in increased expression of GRIA2 mRNA

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

G protein-coupled receptor kinase 5

increases expression

Cytarabine results in increased expression of GRK5 mRNA

NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701

G

gastrin releasing peptide receptor

decreases expression

Cytarabine results in decreased expression of GRPR mRNA

NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442

G

glutathione S-transferase, C-terminal domain containing

increases expression

Cytarabine results in increased expression of GSTCD mRNA

NCBI chr 2:221,499,732...221,591,888
Ensembl chr 2:221,499,083...221,591,857

G

glutathione S-transferase mu 1

affects response to substance

GSTM1 gene polymorphism affects the susceptibility to Cytarabine

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

GTP binding protein 1

increases expression

Cytarabine results in increased expression of GTPBP1 mRNA

NCBI chr 7:111,248,254...111,272,705
Ensembl chr 7:111,248,254...111,272,705

G

guanylate cyclase 1 soluble subunit alpha 1

decreases expression

Cytarabine results in decreased expression of GUCY1A1 mRNA

NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671

G

H1.2 linker histone, cluster member

decreases expression

Cytarabine results in decreased expression of H1-2 mRNA

NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635

G

H2A.J histone

decreases expression

Cytarabine results in decreased expression of H2AJ mRNA

NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006

G

H2A.X variant histone

increases phosphorylation

Cytarabine results in increased phosphorylation of H2AX protein

PMID:19628630 PMID:34510228

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

heart and neural crest derivatives expressed 1

decreases expression

Cytarabine results in decreased expression of HAND1 mRNA

NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213

G

heart and neural crest derivatives expressed 2

decreases expression

Cytarabine results in decreased expression of HAND2 mRNA

NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891

G

hyaluronan and proteoglycan link protein 1

decreases expression

Cytarabine results in decreased expression of HAPLN1 mRNA

NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777

G

hyaluronan synthase 2

decreases expression

Cytarabine results in decreased expression of HAS2 mRNA

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

G

host cell factor C1 regulator 1

decreases expression

Cytarabine results in decreased expression of HCFC1R1 mRNA

NCBI chr10:12,705,139...12,706,852
Ensembl chr10:12,705,077...12,706,850

G

hes family bHLH transcription factor 5

increases expression

Cytarabine results in increased expression of HES5 mRNA

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

G

hes-related family bHLH transcription factor with YRPW motif 1

decreases expression

Cytarabine results in decreased expression of HEY1 mRNA

NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312

G

hypoxia inducible factor 1 subunit alpha

increases expression

Cytarabine results in increased expression of HIF1A mRNA

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

high mobility group box 1

decreases response to substance
increases secretion

HMGB1 protein results in decreased susceptibility to Cytarabine
Cytarabine results in increased secretion of HMGB1 protein

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

Cytarabine results in decreased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heterogeneous nuclear ribonucleoprotein A3

decreases expression

Cytarabine results in decreased expression of HNRNPA3 mRNA

NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306

G

homeobox A2

increases expression

Cytarabine results in increased expression of HOXA2 mRNA

NCBI chr 4:81,262,668...81,266,970
Ensembl chr 4:81,262,768...81,265,044

G

homeo box A5

increases expression

Cytarabine results in increased expression of HOXA5 mRNA

NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234

G

homeo box B4

decreases expression

Cytarabine results in decreased expression of HOXB4 mRNA

NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128

G

homeo box B6

decreases expression

Cytarabine results in decreased expression of HOXB6 mRNA

NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449

G

homeo box B8

decreases expression

Cytarabine results in decreased expression of HOXB8 mRNA

NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638

G

homeo box C6

decreases expression

Cytarabine results in decreased expression of HOXC6 mRNA

NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392

G

homeobox C8

decreases expression

Cytarabine results in decreased expression of HOXC8 mRNA

NCBI chr 7:134,127,937...134,130,503
Ensembl chr 7:134,127,913...134,130,503

G

heparan sulfate-glucosamine 3-sulfotransferase 1

decreases expression

Cytarabine results in decreased expression of HS3ST1 mRNA

NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

Cytarabine results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

HtrA serine peptidase 1

decreases expression

Cytarabine results in decreased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

insulin-like growth factor binding protein 3

decreases expression

Cytarabine results in decreased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 5

decreases expression

Cytarabine results in decreased expression of IGFBP5 mRNA

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

interleukin 6

increases expression

Cytarabine results in increased expression of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

internexin neuronal intermediate filament protein, alpha

increases expression

Cytarabine results in increased expression of INA mRNA

NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330

G

iroquois homeobox 5

increases expression

Cytarabine results in increased expression of IRX5 mRNA

NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318

G

integrin subunit beta 5

decreases expression

Cytarabine results in decreased expression of ITGB5 mRNA

NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472

G

integral membrane protein 2C

decreases expression

Cytarabine results in decreased expression of ITM2C mRNA

NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742

G

junctional adhesion molecule 2

increases expression

Cytarabine results in increased expression of JAM2 mRNA

NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

Cytarabine results in increased expression of JUN; Cytarabine results in increased expression of JUN mRNA

PMID:1450413 PMID:7949469

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

KN motif and ankyrin repeat domains 4

decreases expression

Cytarabine results in decreased expression of KANK4 mRNA

NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555

G

potassium calcium-activated channel subfamily N member 2

decreases expression

Cytarabine results in decreased expression of KCNN2 mRNA

NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347

G

potassium channel tetramerization domain containing 12

decreases expression

Cytarabine results in decreased expression of KCTD12 mRNA

NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282

G

KDEL endoplasmic reticulum protein retention receptor 3

decreases expression

Cytarabine results in decreased expression of KDELR3 mRNA

NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600

G

KIAA1671 homolog

decreases expression

Cytarabine results in decreased expression of KIAA1671 mRNA

NCBI chr12:43,409,479...43,552,152
Ensembl chr12:43,411,069...43,552,157

G

kinesin family member 15

increases expression

Cytarabine results in increased expression of KIF15 mRNA

NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750

G

kelch-like family member 41

decreases expression

Cytarabine results in decreased expression of KLHL41 mRNA

NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222

G

kallikrein related-peptidase 6

decreases expression

Cytarabine results in decreased expression of KLK6 mRNA

NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121

G

kynurenine 3-monooxygenase

increases response to substance

KMO results in increased susceptibility to Cytarabine

NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881

G

lysine methyltransferase 2A

increases response to substance

KMT2A gene mutant form results in increased susceptibility to Cytarabine

NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181

G

karyopherin subunit alpha 2

decreases expression

Cytarabine results in decreased expression of KPNA2 mRNA

NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150

G

keratin 19

decreases expression

Cytarabine results in decreased expression of KRT19 mRNA

NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799

G

keratin 24

decreases expression

Cytarabine results in decreased expression of KRT24 mRNA

NCBI chr10:84,232,163...84,237,299
Ensembl chr10:84,232,164...84,237,299

G

keratin 8

decreases expression

Cytarabine results in decreased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

kynureninase

decreases expression

Cytarabine results in decreased expression of KYNU mRNA

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

G

LBH regulator of WNT signaling pathway

decreases expression

Cytarabine results in decreased expression of LBH mRNA

NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079

G

leptin receptor

decreases expression

Cytarabine results in decreased expression of LEPR mRNA

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

LHFPL tetraspan subfamily member 6

increases expression

Cytarabine results in increased expression of LHFPL6 mRNA

NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443

G

LIM and calponin homology domains 1

increases expression

Cytarabine results in increased expression of LIMCH1 mRNA

NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191

G

LIM and cysteine-rich domains 1

decreases expression

Cytarabine results in decreased expression of LMCD1 mRNA

NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046

G

lysyl oxidase

decreases expression

Cytarabine results in decreased expression of LOX mRNA

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

lysyl oxidase-like 4

decreases expression

Cytarabine results in decreased expression of LOXL4 mRNA

NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322

G

LPS responsive beige-like anchor protein

decreases expression

Cytarabine results in decreased expression of LRBA mRNA

NCBI chr 2:171,623,668...172,202,576
Ensembl chr 2:171,621,507...172,202,724

G

leucine rich repeat and fibronectin type III domain containing 5

decreases expression

Cytarabine results in decreased expression of LRFN5 mRNA

NCBI chr 6:79,466,403...79,822,821
Ensembl chr 6:79,467,961...79,822,815

G

leucine-rich repeats and immunoglobulin-like domains 1

increases expression

Cytarabine results in increased expression of LRIG1 mRNA

NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513

G

LDL receptor related protein 1B

decreases expression

Cytarabine results in decreased expression of LRP1B mRNA

NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505

G

leucine rich repeat containing 32

decreases expression

Cytarabine results in decreased expression of LRRC32 mRNA

NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373

G

leucine rich repeat containing 41

decreases expression

Cytarabine results in decreased expression of LRRC41 mRNA

NCBI chr 5:129,554,547...129,575,450
Ensembl chr 5:129,554,547...129,575,449

G

leucine rich repeat neuronal 2

decreases expression

Cytarabine results in decreased expression of LRRN2 mRNA

NCBI chr13:44,321,944...44,382,454
Ensembl chr13:44,321,364...44,382,482

G

leucine rich repeat neuronal 3

increases expression

Cytarabine results in increased expression of LRRN3 mRNA

NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330

G

leucine rich repeat neuronal 4

decreases expression

Cytarabine results in decreased expression of LRRN4 mRNA

NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831

G

lumican

decreases expression

Cytarabine results in decreased expression of LUM mRNA

NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793

G

lymphocyte antigen 6 family member H

decreases expression

Cytarabine results in decreased expression of LY6H mRNA

NCBI chr 7:107,258,779...107,261,270
Ensembl chr 7:107,258,779...107,261,454

G

lymphocyte antigen 75

increases expression

Cytarabine results in increased expression of LY75 mRNA

NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374

G

LYL1, basic helix-loop-helix family member

decreases response to substance

LYL1 protein results in decreased susceptibility to Cytarabine

NCBI chr19:23,452,140...23,455,007
Ensembl chr19:23,452,140...23,455,007

G

LYN proto-oncogene, Src family tyrosine kinase

decreases expression

Cytarabine results in decreased expression of LYN mRNA

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

G

lysozyme 2

increases expression

Cytarabine results in increased expression of LYZ mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

mab-21 like 2

decreases expression

Cytarabine results in decreased expression of MAB21L2 mRNA

NCBI chr 2:171,946,573...171,949,655
Ensembl chr 2:171,946,573...171,949,655

G

membrane associated guanylate kinase, WW and PDZ domain containing 1

increases expression

Cytarabine results in increased expression of MAGI1 mRNA

NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691

G

microtubule-associated protein 2

decreases expression
increases expression

Cytarabine results in decreased expression of MAP2 protein
Cytarabine results in increased expression of MAP2 mRNA

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

membrane associated ring-CH-type finger 3

decreases expression

Cytarabine results in decreased expression of MARCHF3 mRNA

NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150

G

matrilin 2

decreases expression

Cytarabine results in decreased expression of MATN2 mRNA

NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113

G

mbt domain containing 1

increases expression

Cytarabine results in increased expression of MBTD1 mRNA

NCBI chr10:78,839,140...78,895,413
Ensembl chr10:78,839,036...78,893,720

G

MCL1 apoptosis regulator, BCL2 family member

decreases expression

Cytarabine results in decreased expression of MCL1 protein

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

G

mucolipin TRP cation channel 3

decreases expression

Cytarabine results in decreased expression of MCOLN3 mRNA

NCBI chr 2:235,008,716...235,042,885
Ensembl chr 2:234,966,010...235,043,047

G

midkine

decreases expression

Cytarabine results in decreased expression of MDK mRNA

NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130

G

mediator complex subunit 9

decreases expression

Cytarabine results in decreased expression of MED9 mRNA

NCBI chr10:44,750,667...44,765,464
Ensembl chr10:44,750,698...44,765,464

G

multiple EGF-like domains 10

increases expression

Cytarabine results in increased expression of MEGF10 mRNA

NCBI chr18:50,605,231...50,755,441
Ensembl chr18:50,605,656...50,754,456

G

Meis homeobox 1

increases expression

Cytarabine results in increased expression of MEIS1 mRNA

NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265

G

MER proto-oncogene, tyrosine kinase

decreases expression

Cytarabine results in decreased expression of MERTK mRNA

NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554

G

microfibril associated protein 4

decreases expression

Cytarabine results in decreased expression of MFAP4 mRNA

NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155

G

mitochondria-localized glutamic acid-rich protein

decreases expression

Cytarabine results in decreased expression of MGARP mRNA

NCBI chr 2:135,431,283...135,439,425
Ensembl chr 2:135,431,283...135,439,612

G

matrix Gla protein

decreases expression

Cytarabine results in decreased expression of MGP mRNA

NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667

G

MINDY lysine 48 deubiquitinase 4

decreases expression

Cytarabine results in decreased expression of MINDY4 mRNA

NCBI chr 4:84,358,660...84,469,189
Ensembl chr 4:84,358,902...84,463,395

G

matrix metallopeptidase 23

decreases expression

Cytarabine results in decreased expression of MMP23B mRNA

NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433

G

myelin protein zero-like 1

decreases expression

Cytarabine results in decreased expression of MPZL1 mRNA

NCBI chr13:77,852,467...77,889,305
Ensembl chr13:77,852,467...77,896,616

G

msh homeobox 1

decreases expression

Cytarabine results in decreased expression of MSX1 mRNA

NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966

G

metallothionein 1

decreases expression

Cytarabine results in decreased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

decreases expression

Cytarabine results in decreased expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

decreases expression

Cytarabine results in decreased expression of MT2A mRNA

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

methylenetetrahydrofolate reductase

affects response to substance

MTHFR protein affects the susceptibility to Cytarabine

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

microtubule associated scaffold protein 1

increases expression

Cytarabine results in increased expression of MTUS1 mRNA

NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793

G

multivesicular body subunit 12A

decreases expression

Cytarabine results in decreased expression of MVB12A mRNA

NCBI chr16:18,252,227...18,257,111
Ensembl chr16:18,252,222...18,257,539

G

Max dimerization protein 3

increases expression

Cytarabine results in increased expression of MXD3 mRNA

NCBI chr17:9,301,430...9,305,156
Ensembl chr17:9,301,399...9,305,157

G

matrix remodeling associated 7

decreases expression

Cytarabine results in decreased expression of MXRA7 mRNA

NCBI chr10:102,003,034...102,031,428
Ensembl chr10:102,003,319...102,031,409

G

myeloid-associated differentiation marker

decreases expression

Cytarabine results in decreased expression of MYADM mRNA

NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035

G

myeloid-derived growth factor

decreases expression

Cytarabine results in decreased expression of MYDGF mRNA

NCBI chr 9:999,659...1,008,804
Ensembl chr 9:1,000,722...1,008,822

G

myosin, light chain 4

decreases expression

Cytarabine results in decreased expression of MYL4 mRNA

NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363

G

myosin light chain 7

decreases expression

Cytarabine results in decreased expression of MYL7 mRNA

NCBI chr14:80,780,684...80,783,259
Ensembl chr14:80,779,776...80,783,244

G

myosin regulatory light chain interacting protein

decreases expression

Cytarabine results in decreased expression of MYLIP mRNA

NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295

G

myoferlin

decreases expression

Cytarabine results in decreased expression of MYOF mRNA

NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334

G

neuron navigator 2

decreases expression

Cytarabine results in decreased expression of NAV2 mRNA

NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337

G

neurocalcin delta

increases expression

Cytarabine results in increased expression of NCALD mRNA

NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496

G

NDC80 kinetochore complex component

increases expression

Cytarabine results in increased expression of NDC80 mRNA

NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924

G

N-myc downstream regulated 1

decreases expression

Cytarabine results in decreased expression of NDRG1 mRNA

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NDRG family member 2

decreases expression

Cytarabine results in decreased expression of NDRG2 mRNA

NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626

G

neural EGFL like 2

increases expression

Cytarabine results in increased expression of NELL2 mRNA

NCBI chr 7:126,343,089...126,662,903
Ensembl chr 7:126,198,851...126,733,503

G

nestin

increases expression
decreases expression

Cytarabine results in increased expression of NES mRNA
Cytarabine results in decreased expression of NES protein

NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777

G

nuclear factor I/B

increases expression

Cytarabine results in increased expression of NFIB mRNA

NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479

G

NHERF family PDZ scaffold protein 1

decreases expression

Cytarabine results in decreased expression of NHERF1 mRNA

NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598

G

niban apoptosis regulator 2

decreases expression

Cytarabine results in decreased expression of NIBAN2 mRNA

NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293

G

neuromedin U

increases expression

Cytarabine results in increased expression of NMU mRNA

NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192

G

NOVA alternative splicing regulator 1

increases expression

Cytarabine results in increased expression of NOVA1 mRNA

NCBI chr 6:63,780,105...63,905,567
Ensembl chr 6:63,783,489...63,906,289

G

NADPH oxidase 4

decreases expression

Cytarabine results in decreased expression of NOX4 mRNA

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

G

natriuretic peptide B

increases expression

Cytarabine results in increased expression of NPPB mRNA; Cytarabine results in increased expression of NPPB protein

PMID:16151589 PMID:21198554

NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168

G

neuropeptide Y

decreases expression

Cytarabine results in decreased expression of NPY mRNA

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

G

nuclear receptor interacting protein 3

decreases expression

Cytarabine results in decreased expression of NRIP3 mRNA

NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600

G

neuropilin 1

multiple interactions

[2,2-bis(4-glycidyloxyphenyl)propane co-treated with Cytarabine] results in decreased expression of NRP1 mRNA

NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633

G

neurotrimin

decreases expression

Cytarabine results in decreased expression of NTM mRNA

NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595

G

netrin G1

increases expression

Cytarabine results in increased expression of NTNG1 mRNA

NCBI chr 2:197,462,785...197,827,681
Ensembl chr 2:197,463,945...197,826,997

G

odontogenic, ameloblast associated

decreases expression

Cytarabine results in decreased expression of ODAM mRNA

NCBI chr14:20,193,286...20,202,517
Ensembl chr14:20,193,302...20,202,517

G

olfactomedin-like 3

decreases expression

Cytarabine results in decreased expression of OLFML3 mRNA

NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050

G

oxidized low density lipoprotein receptor 1

decreases expression

Cytarabine results in decreased expression of OLR1 mRNA

NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523

G

oxysterol binding protein-like 10

decreases expression

Cytarabine results in decreased expression of OSBPL10 mRNA

NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:114,660,743...114,918,625

G

odd-skipped related transcription factor 1

decreases expression

Cytarabine results in decreased expression of OSR1 mRNA

NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817

G

prolyl 4-hydroxylase subunit alpha 2

decreases expression

Cytarabine results in decreased expression of P4HA2 mRNA

NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314

G

protein associated with LIN7 2, MAGUK p55 family member

decreases expression

Cytarabine results in decreased expression of PALS2 mRNA

NCBI chr 4:79,173,488...79,257,542
Ensembl chr 4:79,124,806...79,254,140

G

peptidase domain containing associated with muscle regeneration 1

decreases expression

Cytarabine results in decreased expression of PAMR1 mRNA

NCBI chr 3:88,889,061...88,988,615
Ensembl chr 3:88,889,046...88,988,606

G

par-6 family cell polarity regulator alpha

decreases expression

Cytarabine results in decreased expression of PARD6A mRNA

NCBI chr19:33,589,531...33,591,900
Ensembl chr19:33,589,542...33,591,900

G

prostate androgen-regulated mucin-like protein 1

decreases expression

Cytarabine results in decreased expression of PARM1 mRNA

NCBI chr14:16,468,309...16,577,339
Ensembl chr14:16,468,459...16,577,314

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases degradation

[Cytarabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]

PMID:8840993 PMID:12780785

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

paired box 6

increases expression
decreases expression

Cytarabine results in increased expression of PAX6 mRNA
Cytarabine results in decreased expression of PAX6 protein

NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014

G

protocadherin 20

decreases expression

Cytarabine results in decreased expression of PCDH20 mRNA

NCBI chr15:64,425,534...64,431,790
Ensembl chr15:64,425,534...64,431,790

G

protocadherin 7

decreases expression

Cytarabine results in decreased expression of PCDH7 mRNA

NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051

G

PC-esterase domain containing 1B

decreases expression

Cytarabine results in decreased expression of PCED1B mRNA

NCBI chr 7:128,394,388...128,528,231
Ensembl chr 7:128,391,319...128,528,231

G

proprotein convertase subtilisin/kexin type 5

decreases expression

Cytarabine results in decreased expression of PCSK5 mRNA

NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600

G

phosphodiesterase 1A

increases expression

Cytarabine results in increased expression of PDE1A mRNA

NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874

G

phosphodiesterase 1B

increases expression

Cytarabine results in increased expression of PDE1B mRNA

NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580

G

phosphodiesterase 4B

increases expression

Cytarabine results in increased expression of PDE4B mRNA

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

phosphodiesterase 6D

decreases expression

Cytarabine results in decreased expression of PDE6D mRNA

NCBI chr 9:87,192,989...87,237,979
Ensembl chr 9:87,192,983...87,237,969

G

platelet derived growth factor receptor beta

decreases expression

Cytarabine results in decreased expression of PDGFRB mRNA

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

PDZ and LIM domain 3

increases expression

Cytarabine results in increased expression of PDLIM3 mRNA

NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657

G

PDZ and LIM domain 4

multiple interactions

Cytarabine inhibits the reaction [decitabine results in increased expression of PDLIM4 mRNA]

NCBI chr10:38,198,686...38,212,935
Ensembl chr10:38,198,689...38,212,938

G

podoplanin

decreases expression

Cytarabine results in decreased expression of PDPN mRNA

NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656

G

pellino E3 ubiquitin protein ligase 1

increases expression

Cytarabine results in increased expression of PELI1 mRNA

NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285

G

phosphofructokinase, platelet

decreases expression

Cytarabine results in decreased expression of PFKP mRNA

NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018

G

phosphoglucomutase 5

decreases expression

Cytarabine results in decreased expression of PGM5 mRNA

NCBI chr 1:222,325,638...222,513,434
Ensembl chr 1:222,325,643...222,513,437

G

phosphatase and actin regulator 2

decreases expression

Cytarabine results in decreased expression of PHACTR2 mRNA

NCBI chr 1:7,591,254...7,860,431
Ensembl chr 1:7,597,927...7,860,289

G

phytanoyl-CoA 2-hydroxylase interacting protein-like

increases expression

Cytarabine results in increased expression of PHYHIPL mRNA

NCBI chr20:18,024,744...18,065,822
Ensembl chr20:18,024,666...18,065,478

G

phosphatidylinositol glycan anchor biosynthesis, class H

decreases expression

Cytarabine results in decreased expression of PIGH mRNA

NCBI chr 6:97,874,903...97,897,188
Ensembl chr 6:97,882,903...97,897,142

G

paired-like homeodomain 1

decreases expression

Cytarabine results in decreased expression of PITX1 mRNA

NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291

G

paired-like homeodomain 2

decreases expression

Cytarabine results in decreased expression of PITX2 mRNA

NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293

G

cAMP-dependent protein kinase inhibitor alpha

decreases expression

Cytarabine results in decreased expression of PKIA mRNA

NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282

G

plakophilin 2

decreases expression

Cytarabine results in decreased expression of PKP2 mRNA

NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730

G

placenta associated 9

decreases expression

Cytarabine results in decreased expression of PLAC9 mRNA

NCBI chr16:1,459,450...1,474,275
Ensembl chr16:1,459,456...1,474,399

G

plasminogen activator, tissue type

decreases expression

Cytarabine results in decreased expression of PLAT mRNA

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

phospholipase C, beta 2

affects localization
multiple interactions

Cytarabine affects the localization of PLCB2 protein
edelfosine inhibits the reaction [Cytarabine affects the localization of PLCB2 protein]

NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302

G

phospholipase C, eta 1

increases expression

Cytarabine results in increased expression of PLCH1 mRNA

NCBI chr 2:148,148,908...148,363,616
Ensembl chr 2:148,148,921...148,364,097

G

phospholipase D family, member 3

decreases expression

Cytarabine results in decreased expression of PLD3 mRNA

NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072

G

pleckstrin homology and RhoGEF domain containing G3

decreases expression

Cytarabine results in decreased expression of PLEKHG3 mRNA

NCBI chr 6:95,265,756...95,308,952
Ensembl chr 6:95,266,058...95,310,359

G

plasminogen

affects localization

Cytarabine affects the localization of PLG protein

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

G

perilipin 3

decreases expression

Cytarabine results in decreased expression of PLIN3 mRNA

NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147

G

plasmolipin

decreases expression

Cytarabine results in decreased expression of PLLP mRNA

NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892

G

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

decreases expression

Cytarabine results in decreased expression of PLOD1 mRNA

NCBI chr 5:158,340,674...158,367,581
Ensembl chr 5:158,340,490...158,367,620

G

proteolipid protein 1

increases expression

Cytarabine results in increased expression of PLP1 mRNA

NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032

G

phospholipid transfer protein

decreases expression

Cytarabine results in decreased expression of PLTP mRNA

NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647

G

premelanosome protein

increases expression

Cytarabine results in increased expression of PMEL mRNA

NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746

G

peripheral myelin protein 22

decreases expression

Cytarabine results in decreased expression of PMP22 mRNA

NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714

G

podocalyxin-like

decreases expression

Cytarabine results in decreased expression of PODXL mRNA

NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899

G

podocalyxin-like 2

increases expression

Cytarabine results in increased expression of PODXL2 mRNA

NCBI chr 4:121,306,224...121,338,070
Ensembl chr 4:121,306,224...121,338,112

G

periostin

decreases expression

Cytarabine results in decreased expression of POSTN mRNA

NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099

G

peroxisome proliferator-activated receptor gamma

multiple interactions
increases expression

2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Cytarabine results in increased expression of PPARG mRNA]

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

peptidylprolyl isomerase C

decreases expression

Cytarabine results in decreased expression of PPIC mRNA

NCBI chr18:46,842,410...46,855,016
Ensembl chr18:46,842,409...46,855,017

G

protein phosphatase, Mg2+/Mn2+ dependent, 1M

decreases expression

Cytarabine results in decreased expression of PPM1M mRNA

NCBI chr 8:106,836,221...106,843,472
Ensembl chr 8:106,837,037...106,842,057

G

palmitoyl-protein thioesterase 2

decreases expression

Cytarabine results in decreased expression of PPT2 mRNA

NCBI chr20:4,112,520...4,132,774
Ensembl chr20:4,122,463...4,132,774

G

protein regulator of cytokinesis 1

decreases expression

Cytarabine results in decreased expression of PRC1 mRNA

NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765

G

PR/SET domain 8

increases expression

Cytarabine results in increased expression of PRDM8 mRNA

NCBI chr14:11,403,202...11,424,059
Ensembl chr14:11,404,407...11,410,993

G

prickle planar cell polarity protein 1

decreases expression

Cytarabine results in decreased expression of PRICKLE1 mRNA

NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113

G

protein kinase C, zeta

decreases response to substance

PRKCZ protein results in decreased susceptibility to Cytarabine

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

G

prolactin

increases expression

Cytarabine results in increased expression of PRL protein

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

prion protein

decreases expression

Cytarabine results in decreased expression of PRNP mRNA

NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937

G

peripherin

decreases expression

Cytarabine results in decreased expression of PRPH mRNA

NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136

G

proline-rich coiled-coil 2C

decreases expression

Cytarabine results in decreased expression of PRRC2C mRNA

NCBI chr13:75,003,995...75,073,701
Ensembl chr13:75,004,010...75,073,643

G

serine protease 35

decreases expression

Cytarabine results in decreased expression of PRSS35 mRNA

NCBI chr 8:87,714,449...87,731,009
Ensembl chr 8:87,714,966...87,731,009

G

pleckstrin and Sec7 domain containing 3

increases expression

Cytarabine results in increased expression of PSD3 mRNA

NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547

G

proline and serine rich coiled-coil 1

decreases expression

Cytarabine results in decreased expression of PSRC1 mRNA

NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874

G

proline-serine-threonine phosphatase-interacting protein 2

decreases expression

Cytarabine results in decreased expression of PSTPIP2 mRNA

NCBI chr18:71,310,387...71,396,752
Ensembl chr18:71,311,020...71,395,709

G

phosphatase and tensin homolog

increases response to substance

PTEN protein results in increased susceptibility to Cytarabine

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin-endoperoxide synthase 2

multiple interactions

PTGS2 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

parathyroid hormone 1 receptor

decreases expression

Cytarabine results in decreased expression of PTH1R mRNA

NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729

G

protein tyrosine phosphatase, receptor type Z1

increases expression

Cytarabine results in increased expression of PTPRZ1 mRNA

NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218

G

quinolinate phosphoribosyltransferase

decreases expression

Cytarabine results in decreased expression of QPRT mRNA

NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486

G

RAB37, member RAS oncogene family

decreases expression

Cytarabine results in decreased expression of RAB37 mRNA

NCBI chr10:100,334,639...100,401,974
Ensembl chr10:100,334,216...100,401,474

G

RAB5B, member RAS oncogene family

increases expression

Cytarabine results in increased expression of RAB5B mRNA

NCBI chr 7:1,109,449...1,128,348
Ensembl chr 7:1,109,454...1,128,268

G

Rab geranylgeranyltransferase subunit beta

decreases expression

Cytarabine results in decreased expression of RABGGTB mRNA

NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050

G

RAD23 homolog A, nucleotide excision repair protein

decreases expression

Cytarabine results in decreased expression of RAD23A mRNA

NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695

G

RAD51 recombinase

increases expression

Cytarabine results in increased expression of RAD51 mRNA

NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035

G

ral guanine nucleotide dissociation stimulator like 1

decreases expression

Cytarabine results in decreased expression of RGL1 mRNA

NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191

G

receptor activity modifying protein 1

decreases expression

Cytarabine results in decreased expression of RAMP1 mRNA

NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151

G

Ras association domain family member 2

increases expression

Cytarabine results in increased expression of RASSF2 mRNA

NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431

G

RNA binding motif protein 34

decreases expression

Cytarabine results in decreased expression of RBM34 mRNA

NCBI chr19:54,936,516...54,956,810
Ensembl chr19:54,936,531...54,956,715

G

RecQ like helicase 5

decreases expression

Cytarabine results in decreased expression of RECQL5 mRNA

NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
decreases phosphorylation
decreases activity

calyculin A inhibits the reaction [Cytarabine results in decreased activity of RELA protein]
Cytarabine results in decreased phosphorylation of RELA protein

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

reelin

decreases expression

Cytarabine results in decreased expression of RELN mRNA

NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211

G

RAS-like, estrogen-regulated, growth-inhibitor

decreases expression

Cytarabine results in decreased expression of RERG mRNA

NCBI chr 4:169,981,634...170,089,777
Ensembl chr 4:169,982,279...170,089,715

G

REX4 homolog, 3'-5' exonuclease

decreases expression

Cytarabine results in decreased expression of REXO4 mRNA

NCBI chr 3:10,280,654...10,291,003
Ensembl chr 3:10,280,654...10,290,996

G

repulsive guidance molecule BMP co-receptor b

increases expression

Cytarabine results in increased expression of RGMB mRNA

NCBI chr 1:56,766,598...56,792,396
Ensembl chr 1:56,767,850...56,792,425

G

regulator of G-protein signaling 1

decreases expression

Cytarabine results in decreased expression of RGS1 mRNA

NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984

G

regulator of G-protein signaling 13

decreases expression

Cytarabine results in decreased expression of RGS13 mRNA

NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648

G

regulator of G-protein signaling 20

increases expression

Cytarabine results in increased expression of RGS20 mRNA

NCBI chr 5:14,484,436...14,614,317
Ensembl chr 5:14,534,775...14,614,084

G

regulator of G-protein signaling 4

decreases expression

Cytarabine results in decreased expression of RGS4 mRNA

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

ras homolog family member C

decreases expression

Cytarabine results in decreased expression of RHOC mRNA

NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306

G

rhophilin, Rho GTPase binding protein 2

decreases expression

Cytarabine results in decreased expression of RHPN2 mRNA

NCBI chr 1:87,991,143...88,051,895
Ensembl chr 1:87,991,144...88,051,902

G

ribonuclease A family member 2

increases expression

Cytarabine results in increased expression of RNASE2 mRNA

NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479

G

roundabout guidance receptor 3

increases expression

Cytarabine results in increased expression of ROBO3 mRNA

NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315

G

ribonuclease P and MRP subunit p25

decreases expression

Cytarabine results in decreased expression of RPP25 mRNA

NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732

G

reprimo-like

increases expression

Cytarabine results in increased expression of RPRML mRNA

NCBI chr10:88,560,248...88,561,252
Ensembl chr10:88,560,248...88,561,252

G

RAS related

decreases expression

Cytarabine results in decreased expression of RRAS mRNA

NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357

G

ribonucleotide reductase regulatory subunit M2

increases expression

Cytarabine results in increased expression of RRM2 mRNA

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

R-spondin 2

decreases expression

Cytarabine results in decreased expression of RSPO2 mRNA

NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933

G

arginine and serine rich protein 1

decreases expression

Cytarabine results in decreased expression of RSRP1 mRNA

NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523

G

reticulon 1

increases expression

Cytarabine results in increased expression of RTN1 mRNA

NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436

G

RWD domain containing 1

increases expression

Cytarabine results in increased expression of RWDD1 mRNA

NCBI chr20:25,949,723...25,967,147
Ensembl chr20:25,941,966...25,967,193

G

S100 calcium binding protein A10

decreases expression

Cytarabine results in decreased expression of S100A10 mRNA

NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661

G

S100 calcium-binding protein A4

decreases expression

Cytarabine results in decreased expression of S100A4 mRNA

NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254

G

store-operated calcium entry-associated regulatory factor

decreases expression

Cytarabine results in decreased expression of SARAF mRNA

NCBI chr16:58,017,231...58,035,481
Ensembl chr16:58,017,231...58,035,545

G

somatomedin B and thrombospondin, type 1 domain containing

decreases expression

Cytarabine results in decreased expression of SBSPON mRNA

NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420

G

secretory carrier membrane protein 5

increases expression

Cytarabine results in increased expression of SCAMP5 mRNA

NCBI chr 8:57,845,831...57,884,516
Ensembl chr 8:57,846,659...57,872,027

G

SCY1 like pseudokinase 1

decreases expression

Cytarabine results in decreased expression of SCYL1 mRNA

NCBI chr 1:203,045,776...203,059,550
Ensembl chr 1:203,045,741...203,059,533

G

syndecan 4

decreases expression

Cytarabine results in decreased expression of SDC4 mRNA

NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580

G

SEC14-like lipid binding 1

decreases expression

Cytarabine results in decreased expression of SEC14L1 mRNA

NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068

G

selenoprotein M

decreases expression

Cytarabine results in decreased expression of SELENOM mRNA

NCBI chr14:78,395,826...78,398,429
Ensembl chr14:78,395,826...78,398,429

G

semaphorin 5B

increases expression

Cytarabine results in increased expression of SEMA5B mRNA

NCBI chr11:65,102,532...65,225,456
Ensembl chr11:65,102,031...65,225,311

G

serpin family A member 1

increases expression

Cytarabine results in increased expression of SERPINA1 mRNA

NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339

G

serpin family B member 6A

decreases expression

Cytarabine results in decreased expression of SERPINB6 mRNA

NCBI chr17:30,871,468...30,989,703
Ensembl chr17:30,871,468...31,014,427

G

serpin family B member 9

decreases expression

Cytarabine results in decreased expression of SERPINB9 mRNA

NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230

G

serpin family H member 1

decreases expression

Cytarabine results in decreased expression of SERPINH1 mRNA

NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801

G

SERTA domain containing 1

decreases expression

Cytarabine results in decreased expression of SERTAD1 mRNA

NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091

G

sestrin 3

decreases expression

Cytarabine results in decreased expression of SESN3 mRNA

NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842

G

stratifin

decreases response to substance

SFN protein results in decreased susceptibility to Cytarabine

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

secreted frizzled-related protein 1

increases expression

Cytarabine results in increased expression of SFRP1 mRNA

NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286

G

secreted frizzled-related protein 2

increases expression

Cytarabine results in increased expression of SFRP2 mRNA

NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063

G

SH3GL interacting endocytic adaptor 1

increases expression

Cytarabine results in increased expression of SGIP1 mRNA

NCBI chr 5:117,536,752...117,734,593
Ensembl chr 5:117,537,746...117,734,575

G

SH3 domain containing ring finger 2

decreases expression

Cytarabine results in decreased expression of SH3RF2 mRNA

NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856

G

signal-induced proliferation-associated 1 like 2

decreases expression

Cytarabine results in decreased expression of SIPA1L2 mRNA

NCBI chr19:53,389,792...53,540,466
Ensembl chr19:53,389,805...53,540,428

G

src-like adaptor

increases expression

Cytarabine results in increased expression of SLA mRNA

NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648

G

solute carrier family 12, member 6

decreases expression

Cytarabine results in decreased expression of SLC12A6 mRNA

NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258

G

solute carrier family 16 member 3

decreases expression

Cytarabine results in decreased expression of SLC16A3 mRNA

NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562

G

solute carrier family 16, member 9

increases expression

Cytarabine results in increased expression of SLC16A9 mRNA

NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022

G

solute carrier family 17 member 6

increases expression

Cytarabine results in increased expression of SLC17A6 mRNA

NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542

G

solute carrier family 28 member 1

multiple interactions

Cytarabine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine]
Cytarabine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]

PMID:8713072 PMID:10772724

NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464

G

solute carrier family 29 member 1

decreases response to substance

SLC29A1 gene polymorphism results in decreased susceptibility to Cytarabine

NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203

G

solute carrier family 2 member 1

decreases expression

Cytarabine results in decreased expression of SLC2A1 mRNA

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 39 member 2

decreases expression

Cytarabine results in decreased expression of SLC39A2 mRNA

NCBI chr15:24,590,738...24,592,850
Ensembl chr15:24,590,738...24,592,850

G

solute carrier family 40 member 1

decreases expression

Cytarabine results in decreased expression of SLC40A1 mRNA

NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481

G

solute carrier family 43, member 3

increases expression

Cytarabine results in increased expression of SLC43A3 mRNA

NCBI chr 3:70,008,160...70,030,324
Ensembl chr 3:70,009,313...70,029,749

G

solute carrier family 47 member 1

decreases expression

Cytarabine results in decreased expression of SLC47A1 mRNA

NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637

G

solute carrier family 4 member 8

decreases expression

Cytarabine results in decreased expression of SLC4A8 mRNA

NCBI chr 7:131,861,284...131,939,295
Ensembl chr 7:131,864,102...131,931,051

G

solute carrier family 5 member 12

decreases expression

Cytarabine results in decreased expression of SLC5A12 mRNA

NCBI chr 3:97,179,326...97,228,405
Ensembl chr 3:97,179,326...97,228,405

G

solute carrier family 7 member 2

decreases expression

Cytarabine results in decreased expression of SLC7A2 mRNA

NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784

G

solute carrier family 7 member 7

decreases expression

Cytarabine results in decreased expression of SLC7A7 mRNA

NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648

G

schlafen family member 9

increases expression

Cytarabine results in increased expression of SLFN11 mRNA

NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383

G

slit guidance ligand 2

decreases expression

Cytarabine results in decreased expression of SLIT2 mRNA

NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948

G

SLIT and NTRK-like family, member 3

decreases expression

Cytarabine results in decreased expression of SLITRK3 mRNA

NCBI chr 2:157,680,067...157,697,404
Ensembl chr 2:157,687,535...157,696,709

G

SLIT and NTRK-like family, member 5

decreases expression

Cytarabine results in decreased expression of SLITRK5 mRNA

NCBI chr15:88,848,123...88,858,809
Ensembl chr15:88,847,535...88,856,836

G

sarcolipin

decreases expression

Cytarabine results in decreased expression of SLN mRNA

NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791

G

SMAD family member 6

decreases expression

Cytarabine results in decreased expression of SMAD6 mRNA

NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763

G

SPARC related modular calcium binding 2

decreases expression

Cytarabine results in decreased expression of SMOC2 mRNA

NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693

G

sphingomyelin phosphodiesterase, acid-like 3A

decreases expression

Cytarabine results in decreased expression of SMPDL3A mRNA

NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567

G

snail family transcriptional repressor 2

decreases expression

Cytarabine results in decreased expression of SNAI2 mRNA

NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200

G

synaptosome associated protein 91

increases expression

Cytarabine results in increased expression of SNAP91 mRNA

NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367

G

synuclein alpha

multiple interactions

Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to ferrous chloride]; Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron]

NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262

G

staphylococcal nuclease and tudor domain containing 1

decreases expression

Cytarabine results in decreased expression of SND1 mRNA

NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843

G

SNF8 subunit of ESCRT-II

decreases expression

Cytarabine results in decreased expression of SNF8 mRNA

NCBI chr10:80,984,337...80,996,724
Ensembl chr10:80,984,363...80,996,734

G

sorbin and SH3 domain containing 2

increases expression

Cytarabine results in increased expression of SORBS2 mRNA

NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514

G

SRY-box transcription factor 21

increases expression

Cytarabine results in increased expression of SOX21 mRNA

NCBI chr15:95,292,429...95,296,024
Ensembl chr15:95,292,265...95,296,091

G

SRY-box transcription factor 3

increases expression

Cytarabine results in increased expression of SOX3 mRNA

NCBI chr X:139,308,608...139,310,687
Ensembl chr X:139,309,329...139,310,678

G

sperm associated antigen 16

increases expression

Cytarabine results in increased expression of SPAG16 mRNA

NCBI chr 9:71,333,005...72,252,772
Ensembl chr 9:71,332,992...72,252,708

G

secreted protein acidic and cysteine rich

decreases expression

Cytarabine results in decreased expression of SPARC mRNA

NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396

G

spermatogenesis associated 7

increases expression

Cytarabine results in increased expression of SPATA7 mRNA

NCBI chr 6:117,879,828...117,925,284
Ensembl chr 6:117,879,823...117,925,284

G

spindlin family, member 4

decreases expression

Cytarabine results in decreased expression of SPIN4 mRNA

NCBI chr X:59,888,728...59,892,817
Ensembl chr X:59,891,581...59,892,330

G

serine peptidase inhibitor, Kazal type 1

increases expression

Cytarabine results in increased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

spondin 1

decreases expression

Cytarabine results in decreased expression of SPON1 mRNA

NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226

G

serine palmitoyltransferase, long chain base subunit 3

decreases expression

Cytarabine results in decreased expression of SPTLC3 mRNA

NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010

G

SLIT-ROBO Rho GTPase activating protein 3

increases expression

Cytarabine results in increased expression of SRGAP3 mRNA

PMID:21198554 PMID:33770205

NCBI chr 4:145,839,369...146,070,556
Ensembl chr 4:145,840,078...146,070,575

G

serglycin

increases expression

Cytarabine results in increased expression of SRGN mRNA

NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406

G

sulfiredoxin 1

increases expression

Cytarabine results in increased expression of SRXN1 mRNA

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

ssu-2 homolog

increases expression

Cytarabine results in increased expression of SSUH2 mRNA

NCBI chr 4:145,502,942...145,521,881
Ensembl chr 4:145,503,185...145,521,735

G

ST18 C2H2C-type zinc finger transcription factor

increases expression

Cytarabine results in increased expression of ST18 mRNA

NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

decreases expression

Cytarabine results in decreased expression of ST3GAL1 mRNA

NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

decreases expression

Cytarabine results in decreased expression of ST3GAL5 mRNA

NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

decreases expression

Cytarabine results in decreased expression of ST3GAL6 mRNA

NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

decreases expression

Cytarabine results in decreased expression of ST6GALNAC3 mRNA

NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

decreases expression

Cytarabine results in decreased expression of ST6GALNAC6 mRNA

NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496

G

stathmin 4

increases response to substance

STMN4 results in increased susceptibility to Cytarabine

NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253

G

stomatin

decreases expression

Cytarabine results in decreased expression of STOM mRNA

NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354

G

stonin 1

decreases expression

Cytarabine results in decreased expression of STON1 mRNA

NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449

G

surfeit 4

decreases expression

Cytarabine results in decreased expression of SURF4 mRNA

NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315

G

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

decreases expression

Cytarabine results in decreased expression of SVEP1 mRNA

NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525

G

synaptotagmin-like 2

increases expression

Cytarabine results in increased expression of SYTL2 mRNA

NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222

G

tachykinin, precursor 1

increases expression

Cytarabine results in increased expression of TAC1 mRNA

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

G

tachykinin precursor 3

decreases expression

Cytarabine results in decreased expression of TAC3 mRNA

NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170

G

transgelin

increases expression

Cytarabine results in increased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

TBC1 domain family, member 4

decreases expression

Cytarabine results in decreased expression of TBC1D4 mRNA

NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265

G

transcription elongation factor A like 7

increases expression

Cytarabine results in increased expression of TCEAL7 mRNA

NCBI chr X:99,228,405...99,230,551
Ensembl chr X:99,228,458...99,230,543

G

transcription factor 12

increases expression

Cytarabine results in increased expression of TCF12 mRNA

NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201

G

transcription factor 21

decreases expression

Cytarabine results in decreased expression of TCF21 mRNA

NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202

G

transcription factor 25

decreases expression

Cytarabine results in decreased expression of TCF25 mRNA

NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723

G

trans-2,3-enoyl-CoA reductase-like

decreases expression

Cytarabine results in decreased expression of TECRL mRNA

NCBI chr14:24,732,241...24,805,272
Ensembl chr14:24,732,241...24,805,272

G

TEK receptor tyrosine kinase

decreases expression

Cytarabine results in decreased expression of TEK mRNA

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

G

terminal nucleotidyltransferase 5A

decreases expression

Cytarabine results in decreased expression of TENT5A mRNA

NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045

G

terminal nucleotidyltransferase 5C

decreases expression

Cytarabine results in decreased expression of TENT5C mRNA

NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744

G

transcription factor AP-2 alpha

multiple interactions
increases expression

2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Cytarabine results in increased expression of TFAP2A mRNA]

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

G

transcription factor binding to IGHM enhancer 3

increases expression

Cytarabine results in increased expression of TFE3 mRNA

NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571

G

trefoil factor 3

increases expression

Cytarabine results in increased expression of TFF3 mRNA

NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054

G

tissue factor pathway inhibitor

decreases expression

Cytarabine results in decreased expression of TFPI mRNA

NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880

G

transforming growth factor beta receptor 3

decreases expression

Cytarabine results in decreased expression of TGFBR3 mRNA

NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341

G

tyrosine hydroxylase

decreases expression

Cytarabine results in decreased expression of TH protein

NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767

G

thrombospondin 1

increases expression

Cytarabine results in increased expression of THBS1 mRNA

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

Thy-1 cell surface antigen

decreases expression

Cytarabine results in decreased expression of THY1 mRNA

NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659

G

TIMP metallopeptidase inhibitor 1

decreases expression

Cytarabine results in decreased expression of TIMP1 mRNA

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

TIMP metallopeptidase inhibitor 3

affects response to substance
decreases response to substance

TIMP3 protein affects the susceptibility to Cytarabine
TIMP3 gene modified form results in decreased susceptibility to Cytarabine

NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839

G

thymidine kinase 1

decreases activity
decreases expression

Cytarabine results in decreased activity of TK1 protein
Cytarabine results in decreased expression of TK1 mRNA

NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920

G

thymidine kinase 2

decreases expression
decreases activity

Cytarabine results in decreased expression of TK2 mRNA
Cytarabine results in decreased activity of TK2 protein

NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924

G

talin 2

decreases expression

Cytarabine results in decreased expression of TLN2 mRNA

NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219

G

transmembrane p24 trafficking protein 1

decreases expression

Cytarabine results in decreased expression of TMED1 mRNA

NCBI chr 8:20,059,937...20,063,567
Ensembl chr 8:20,059,892...20,063,677

G

transmembrane p24 trafficking protein 9

decreases expression

Cytarabine results in decreased expression of TMED9 mRNA

NCBI chr17:9,029,646...9,034,160
Ensembl chr17:9,029,646...9,034,176

G

transmembrane protein 200A

decreases expression

Cytarabine results in decreased expression of TMEM200A mRNA

NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:19,323,829...19,406,453

G

transmembrane protein 45A

decreases expression

Cytarabine results in decreased expression of TMEM45A mRNA

NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526

G

transmembrane protein 62

increases expression

Cytarabine results in increased expression of TMEM62 mRNA

NCBI chr 3:107,921,940...107,961,830
Ensembl chr 3:107,927,307...107,961,795

G

transmembrane protein 88

decreases expression

Cytarabine results in decreased expression of TMEM88 mRNA

NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447

G

transmembrane protein 98

decreases expression

Cytarabine results in decreased expression of TMEM98 mRNA

NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079

G

tumor necrosis factor

increases expression

Cytarabine results in increased expression of TNF protein

PMID:8318674 PMID:11745875

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 3

decreases expression

Cytarabine results in decreased expression of TNFAIP3 mRNA

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

G

TNF receptor superfamily member 19

decreases expression

Cytarabine results in decreased expression of TNFRSF19 mRNA

NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795

G

TNF superfamily member 10

multiple interactions
increases expression

[Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; [Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; [Cytarabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; [Cytarabine co-treated with TNFSF10 protein] results in increased expression of BID protein; Cytarabine promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Cytarabine promotes the reaction [TNFSF10 protein results in increased expression of TNFRSF10B protein]
Cytarabine results in increased expression of TNFSF10 mRNA

PMID:12780785 PMID:18549619 PMID:19194470

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

troponin T2, cardiac type

decreases expression

Cytarabine results in decreased expression of TNNT2 mRNA

NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388

G

trinucleotide repeat containing adaptor 6A

increases expression

Cytarabine results in increased expression of TNRC6A mRNA

NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660

G

tumor protein p53

multiple interactions
affects activity
increases activity
affects response to substance
increases response to substance
increases expression
increases phosphorylation

[fludarabine co-treated with Cytarabine co-treated with docetaxel] results in increased expression of TP53 protein; Caffeine inhibits the reaction [Cytarabine results in increased expression of TP53 protein]; Caffeine inhibits the reaction [Cytarabine results in increased phosphorylation of TP53 protein]
Cytarabine affects the activity of TP53 protein; Cytarabine metabolite affects the activity of TP53 protein
Cytarabine results in increased activity of TP53 protein
TRP53 protein affects the susceptibility to Cytarabine
TP53 gene mutant form results in increased susceptibility to Cytarabine
[Cytarabine results in increased expression of TP53 protein] which results in increased expression of BAX protein; Cytarabine results in increased expression of TP53 protein

PMID:9703875 PMID:9880587 PMID:10200513 PMID:12082016 PMID:12781215 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p53 inducible protein 11

increases response to substance

TP53I11 results in increased susceptibility to Cytarabine

NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050

G

thiamin pyrophosphokinase 1

decreases expression

Cytarabine results in decreased expression of TPK1 mRNA

NCBI chr 4:72,170,134...72,557,707
Ensembl chr 4:72,170,134...72,557,694

G

tyrosylprotein sulfotransferase 1

decreases expression

Cytarabine results in decreased expression of TPST1 mRNA

NCBI chr12:26,544,536...26,605,706
Ensembl chr12:26,544,536...26,605,704

G

tripartite motif-containing 5

decreases expression

Cytarabine results in decreased expression of TRIM5 mRNA

NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012

G

tripartite motif containing 6

decreases expression

Cytarabine results in decreased expression of TRIM6 mRNA

NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914

G

transient receptor potential cation channel, subfamily V, member 1

affects localization

Cytarabine affects the localization of TRPV1 protein

NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513

G

transient receptor potential cation channel, subfamily V, member 2

decreases expression

Cytarabine results in decreased expression of TRPV2 mRNA

NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260

G

tetraspanin 4

decreases expression

Cytarabine results in decreased expression of TSPAN4 mRNA

NCBI chr 1:196,571,307...196,593,842
Ensembl chr 1:196,572,228...196,617,448

G

translocator protein

decreases expression

Cytarabine results in decreased expression of TSPO mRNA

NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450

G

thiosulfate sulfurtransferase

decreases expression

Cytarabine results in decreased expression of TST mRNA

NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216

G

tweety family member 1

increases expression

Cytarabine results in increased expression of TTYH1 mRNA

NCBI chr 1:70,053,312...70,071,872
Ensembl chr 1:70,053,324...70,071,845

G

tubulin, beta 3 class III

decreases expression

Cytarabine results in decreased expression of TUBB3 protein

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

G

thymidylate synthetase

affects response to substance
increases activity

TYMS gene polymorphism affects the susceptibility to Cytarabine
Cytarabine results in increased activity of TYMS protein

PMID:15713801 PMID:15816533

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

U2 small nuclear RNA auxiliary factor 1

decreases expression

Cytarabine results in decreased expression of U2AF1 mRNA

NCBI chr20:9,742,904...9,753,840
Ensembl chr20:9,742,905...9,753,832

G

ubiquitin-conjugating enzyme E2C

decreases expression

Cytarabine results in decreased expression of UBE2C mRNA

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

G

ubiquitin-like 3

increases expression

Cytarabine results in increased expression of UBL3 mRNA

NCBI chr12:6,473,684...6,518,331
Ensembl chr12:6,473,460...6,518,862

G

ubiquitin specific peptidase 7

decreases expression

Cytarabine results in decreased expression of USP7 mRNA

NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355

G

vasorin

decreases expression

Cytarabine results in decreased expression of VASN mRNA

NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357

G

vascular cell adhesion molecule 1

increases expression

Cytarabine results in increased expression of VCAM1 mRNA

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

G

vitamin D receptor

affects response to substance

VDR gene polymorphism affects the susceptibility to Cytarabine

NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677

G

vascular endothelial growth factor C

multiple interactions
decreases response to substance

EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]; PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
EDN1 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]; PTGS2 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]

NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848

G

vascular endothelial zinc finger 1

increases expression

Cytarabine results in increased expression of VEZF1 mRNA

NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111

G

vestigial-like family member 4

decreases expression

Cytarabine results in decreased expression of VGLL4 mRNA

NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471

G

VRK serine/threonine kinase 2

decreases expression

Cytarabine results in decreased expression of VRK2 mRNA

NCBI chr14:100,313,771...100,434,520
Ensembl chr14:100,313,601...100,434,527

G

WAP four-disulfide core domain 3

decreases expression

Cytarabine results in decreased expression of WFDC3 mRNA

NCBI chr 3:153,464,862...153,478,952
Ensembl chr 3:153,464,862...153,478,952

G

WAS/WASL interacting protein family, member 1

decreases expression

Cytarabine results in decreased expression of WIPF1 mRNA

NCBI chr 3:58,314,521...58,416,668
Ensembl chr 3:58,314,542...58,372,742

G

X-linked inhibitor of apoptosis

increases response to substance

XIAP protein results in increased susceptibility to Cytarabine

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

G

X-ray repair cross complementing 1

increases expression

Cytarabine results in increased expression of XRCC1 mRNA

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

Yip1 interacting factor homolog A, membrane trafficking protein

decreases expression

Cytarabine results in decreased expression of YIF1A mRNA

NCBI chr 1:202,394,923...202,399,125
Ensembl chr 1:202,394,897...202,399,427

G

zinc finger CCCH-type containing, antiviral 1

decreases expression

Cytarabine results in decreased expression of ZC3HAV1 mRNA

NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428

G

zinc finger homeobox 4

increases expression

Cytarabine results in increased expression of ZFHX4 mRNA

NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228

G

zinc finger protein 282

increases expression

Cytarabine results in increased expression of ZNF282 mRNA

NCBI chr 4:76,884,996...76,910,250
Ensembl chr 4:76,884,924...76,911,370

G

zinc finger protein 423

increases expression

Cytarabine results in increased expression of ZNF423 mRNA

NCBI chr19:19,111,213...19,407,373
Ensembl chr19:19,110,238...19,407,373

G

zinc finger protein 467

decreases expression

Cytarabine results in decreased expression of ZNF467 mRNA

NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229

G

zinc finger protein, multitype 2

decreases expression

Cytarabine results in decreased expression of ZFPM2 mRNA

NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:71,678,880...72,116,205

cytidine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenosine A1 receptor

increases activity

Cytidine results in increased activity of ADORA1 protein

NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801

G

adenosine A2a receptor

increases activity

Cytidine results in increased activity of ADORA2A protein

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

C-C motif chemokine ligand 5

multiple interactions

[Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

glycophorin A

multiple interactions