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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:succinic acid
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Accession:CHEBI:15741 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Synonyms:related_synonym: 1,2-ethanedicarboxylic acid;   Bernsteinsaeure;   Butandisaeure;   Butanedionic acid;   Dihydrofumaric acid;   E363;   Ethylenesuccinic acid;   Formula=C4H6O4;   HOOC-CH2-CH2-COOH;   InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8);   InChIKey=KDYFGRWQOYBRFD-UHFFFAOYSA-N;   SMILES=OC(=O)CCC(O)=O;   acide butanedioique;   acide succinique;   acidum succinicum;   amber acid;   asuccin;   butanedioic acid;   spirit of amber
 alt_id: CHEBI:22943;   CHEBI:26807;   CHEBI:45639;   CHEBI:9304
 xref: Beilstein:1754069;   CAS:110-15-6;   DrugBank:DB00139;   Drug_Central:2487;   ECMDB:ECMDB00254;   Gmelin:2785;   HMDB:HMDB0000254;   KEGG:C00042;   KNApSAcK:C00001205;   LIPID_MAPS_instance:LMFA01170043
 xref_mesh: MESH:D019802
 xref: MetaCyc:SUC;   PDBeChem:SIN;   PMID:17439666;   Reaxys:1754069;   Wikipedia:Succinic_acid;   YMDB:YMDB00338
 cyclic_relationship: is_conjugate_acid_of CHEBI:30779


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succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
decreases abundance		 ISO IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Succinic Acid]; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Succinic Acid]
APP protein mutant form results in decreased abundance of Succinic Acid
PF-06840003 inhibits the reaction [APP protein mutant form results in decreased abundance of Succinic Acid]		 CTD PMID:39172838 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in increased expression of BAX mRNA; [Oleanolic Acid analog binds to Succinic Acid] which results in increased expression of BAX protein CTD PMID:31401087 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of BCL2L1 mRNA; [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of BCL2L1 protein CTD PMID:31401087 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid] CTD PMID:24709313 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Dek DEK proto-oncogene multiple interactions ISO DEK protein affects the chemical synthesis of and affects the secretion of Succinic Acid CTD PMID:28558019 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases abundance ISO ERCC6 gene mutant form results in increased abundance of Succinic Acid CTD PMID:25440059 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions EXP Succinic Acid inhibits the reaction [Rotenone affects the expression of HIF1A protein] CTD PMID:16034640 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Succinic Acid] CTD PMID:39172838 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Succinic Acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
decreases abundance		 ISO PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Succinic Acid] CTD PMID:39172838 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of MYC mRNA; [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of MYC protein CTD PMID:31401087 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of NFKB1 mRNA CTD PMID:31401087 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA CTD PMID:20505214 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Psen1 presenilin 1 multiple interactions ISO IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Succinic Acid]; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Succinic Acid] CTD PMID:39172838 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of PTGS2 mRNA; [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of PTGS2 protein CTD PMID:31401087 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of RELA mRNA CTD PMID:31401087 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Slc13a3 solute carrier family 13 member 3 affects binding ISO
EXP		 Succinic Acid binds to SLC13A3 protein CTD PMID:12397032 NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606 		JBrowse link
G Slc22a19 solute carrier family 22, member 19 multiple interactions EXP Succinic Acid affects the reaction [SLC22A19 protein affects the transport of estrone sulfate] CTD PMID:16079298 NCBI chr 1:204,910,450...204,965,538
Ensembl chr 1:204,910,455...204,965,538 		JBrowse link
G Slc22a25 solute carrier family 22, member 25 multiple interactions EXP Succinic Acid inhibits the reaction [SLC22A9 protein affects the transport of estrone sulfate] CTD PMID:18441515 NCBI chr 1:205,338,698...205,498,486
Ensembl chr 1:205,338,699...205,433,085 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases activity		 ISO [Succinic Acid results in increased activity of SLC22A6 protein] which results in increased uptake of p-Aminohippuric Acid CTD PMID:36958672 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases activity		 ISO [Succinic Acid results in increased activity of SLC22A8 protein] which results in increased uptake of p-Aminohippuric Acid CTD PMID:36958672 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects abundance ISO SLCO1A4 protein affects the abundance of Succinic Acid CTD PMID:21561886 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of STAT3 mRNA CTD PMID:31401087 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
artesunate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression		 ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA]
Artesunate results in decreased expression of ACTA2 mRNA; Artesunate results in decreased expression of ACTA2 protein
Artesunate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]		 CTD PMID:30551460 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO artesunate affects the localization of AIFM1 protein CTD PMID:24704559 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ar androgen receptor multiple interactions ISO artesunate binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO Artesunate results in increased expression of ATG12 mRNA CTD PMID:30551460 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg3 autophagy related 3 increases expression ISO Artesunate results in increased expression of ATG3 mRNA CTD PMID:30551460 NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224 		JBrowse link
G Atg5 autophagy related 5 increases expression ISO Artesunate results in increased expression of ATG5 mRNA CTD PMID:30551460 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 Artesunate results in increased expression of BAX protein
[1,2-Dimethylhydrazine co-treated with artesunate] results in increased expression of BAX protein		 CTD PMID:24704559 PMID:29031619 PMID:33002460 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO
EXP		 Artesunate results in decreased expression of BCL2 protein
3-methyladenine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; acadesine promotes the reaction [Artesunate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; dorsomorphin inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; Sirolimus promotes the reaction [Artesunate results in decreased expression of BCL2 protein]
[1,2-Dimethylhydrazine co-treated with artesunate] results in decreased expression of BCL2 protein		 CTD PMID:24704559 PMID:29031619 PMID:33002460 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 increases response to substance ISO BST1 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
multiple interactions		 ISO artesunate results in increased activity of CASP3 protein
Artesunate results in increased cleavage of CASP3 protein
3-methyladenine inhibits the reaction [Artesunate results in increased cleavage of CASP3 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [Artesunate results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Artesunate results in increased cleavage of CASP3 protein]		 CTD PMID:19513562 PMID:24704559 PMID:33002460 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 affects expression ISO artesunate affects the expression of CASP9 protein CTD PMID:24704559 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases expression
decreases response to substance		 ISO artesunate results in increased expression of CAT protein
CAT protein results in decreased susceptibility to artesunate		 CTD PMID:19513562 PMID:20144594 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 decreases response to substance ISO CCT2 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions
increases phosphorylation		 ISO APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of CHEK1 protein] CTD PMID:31664825 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases phosphorylation		 ISO APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of CHEK2 protein] CTD PMID:31664825 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 increases response to substance ISO CLIP4 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874 		JBrowse link
G Coq8a coenzyme Q8A decreases response to substance ISO COQ8A mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein] CTD PMID:29031619 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance ISO DBH mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Des desmin multiple interactions
decreases expression		 ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]
Artesunate results in decreased expression of DES mRNA; Artesunate results in decreased expression of DES protein		 CTD PMID:30551460 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO artesunate binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO artesunate results in increased expression of FAS protein CTD PMID:19513562 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Flna filamin A increases response to substance ISO FLNA mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
decreases expression		 ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA]
Artesunate results in decreased expression of FN1 mRNA; Artesunate results in decreased expression of FN1 protein		 CTD PMID:30551460 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression
multiple interactions		 ISO Artesunate results in decreased expression of FTH1 mRNA; Artesunate results in decreased expression of FTH1 protein
Chloroquine inhibits the reaction [Artesunate results in decreased expression of FTH1 mRNA]		 CTD PMID:30551460 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fzd7 frizzled class receptor 7 increases response to substance ISO FZD7 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects response to substance
decreases response to substance		 ISO GCLC mRNA affects the susceptibility to artesunate
GCLC mRNA results in decreased susceptibility to artesunate		 CTD PMID:15796179 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases response to substance ISO GCLM mRNA results in decreased susceptibility to artesunate CTD PMID:15796179 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases activity
multiple interactions		 ISO Artesunate results in decreased activity of GPX4 protein
Artesunate inhibits the reaction [Carbon Tetrachloride results in increased expression of GPX4 protein]		 CTD PMID:30551460 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 affects response to substance ISO GSTM4 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO artesunate results in decreased expression of GSTP1 protein CTD PMID:19513562 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt2 glutathione S-transferase theta 2 affects response to substance ISO GSTT2 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 affects response to substance ISO GSTZ1 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation		 ISO APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of H2AX protein] CTD PMID:31664825 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Artesunate inhibits the reaction [Ethanol results in increased expression of IL1B protein]; Artesunate inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL1B protein] CTD PMID:27474069 PMID:30031708 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Artesunate inhibits the reaction [Ethanol results in increased expression of IL6 protein]; Artesunate inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL6 protein] CTD PMID:27474069 PMID:30031708 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgb1 integrin subunit beta 1 increases response to substance ISO ITGB1 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation		 ISO 3-methyladenine inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; acadesine promotes the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; dorsomorphin inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; Sirolimus promotes the reaction [Artesunate results in increased lipidation of MAP1LC3B protein] CTD PMID:33002460 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 affects response to substance ISO MGST3 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein] CTD PMID:29031619 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression		 EXP
ISO		 artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MMP9 protein]
Chloroquine inhibits the reaction [Artesunate results in decreased expression of MMP9 mRNA]		 CTD PMID:29031619 PMID:30551460 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP artesunate inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:27474069 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases response to substance ISO MTHFD2 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation		 ISO acadesine promotes the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein] CTD PMID:33002460 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP artesunate inhibits the reaction [Glucose results in increased expression of MYD88 protein] CTD PMID:30031708 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naca nascent polypeptide associated complex subunit alpha decreases response to substance ISO NACA mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992 		JBrowse link
G Nckap1 NCK-associated protein 1 increases response to substance ISO NCKAP1 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions
decreases expression		 ISO Chloroquine inhibits the reaction [Artesunate results in decreased expression of NCOA4 mRNA]
Artesunate results in decreased expression of NCOA4 mRNA; Artesunate results in decreased expression of NCOA4 protein		 CTD PMID:30551460 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization ISO artesunate affects the localization of NFE2L2 protein CTD PMID:26340163 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP artesunate inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:30031708 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO Artesunate results in increased cleavage of PARP1 protein
3-methyladenine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; acadesine promotes the reaction [Artesunate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; dorsomorphin inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; Sirolimus promotes the reaction [Artesunate results in increased cleavage of PARP1 protein]		 CTD PMID:24704559 PMID:33002460 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein] CTD PMID:29031619 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO artesunate binds to and results in increased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Carbon Tetrachloride results in increased susceptibility to Artesunate] which results in increased expression of PTGS2 mRNA; [Carbon Tetrachloride results in increased susceptibility to Artesunate] which results in increased expression of PTGS2 protein CTD PMID:30551460 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP artesunate inhibits the reaction [Ethanol results in increased expression of RELA protein]; artesunate inhibits the reaction [Glucose results in increased phosphorylation of RELA protein] CTD PMID:27474069 PMID:30031708 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rpa2 replication protein A2 increases phosphorylation ISO Artesunate results in increased phosphorylation of RPA2 protein CTD PMID:31664825 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpl41 ribosomal protein L41 decreases response to substance ISO RPL41 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 7:977,885...978,965 JBrowse link
G Rpl6 ribosomal protein L6 decreases response to substance ISO RPL6 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921 		JBrowse link
G Rpl7 ribosomal protein L7 decreases response to substance ISO RPL7 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 5:3,217,184...3,220,192 JBrowse link
G Rps12 ribosomal protein S12 decreases response to substance ISO RPS12 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps15a ribosomal protein S15a decreases response to substance ISO RPS15A mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995 		JBrowse link
G Rps6 ribosomal protein S6 decreases response to substance ISO RPS6 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Slc25a19 solute carrier family 25 member 19 decreases response to substance ISO SLC25A19 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447 		JBrowse link
G Sp1 Sp1 transcription factor decreases expression ISO artesunate results in decreased expression of SP1 protein CTD PMID:19513562 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression		 ISO Chloroquine inhibits the reaction [Artesunate results in decreased expression of SQSTM1 protein]
Artesunate results in decreased expression of SQSTM1 mRNA; Artesunate results in decreased expression of SQSTM1 protein		 CTD PMID:30551460 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases response to substance ISO SRSF2 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions		 ISO Artesunate results in increased expression of TIMP1 mRNA
Chloroquine inhibits the reaction [Artesunate results in increased expression of TIMP1 mRNA]		 CTD PMID:30551460 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] CTD PMID:30031708 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP artesunate inhibits the reaction [Ethanol results in increased expression of TNF protein]; artesunate inhibits the reaction [Glucose results in increased expression of TNF mRNA]; artesunate inhibits the reaction [Glucose results in increased secretion of TNF protein] CTD PMID:27474069 PMID:30031708 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO Artesunate results in increased expression of TP53 protein
Artesunate inhibits the reaction [TPT1 protein binds to TP53 protein]		 CTD PMID:33259807 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 affects response to substance
multiple interactions		 ISO TPT1 protein affects the susceptibility to artesunate
Artesunate binds to and results in decreased expression of TPT1 protein; Artesunate inhibits the reaction [TPT1 protein binds to TP53 protein]		 CTD PMID:15878303 PMID:33259807 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
G Tufm Tu translation elongation factor, mitochondrial decreases response to substance ISO TUFM mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases phosphorylation
multiple interactions		 ISO Artesunate results in increased phosphorylation of ULK1 protein
acadesine promotes the reaction [Artesunate results in increased phosphorylation of ULK1 protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased phosphorylation of ULK1 protein]; dorsomorphin inhibits the reaction [Artesunate results in increased phosphorylation of ULK1 protein]		 CTD PMID:33002460 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of VEGFA protein] CTD PMID:29031619 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Yy1 YY1 transcription factor decreases expression ISO artesunate results in decreased expression of YY1 protein CTD PMID:19513562 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zbtb4 zinc finger and BTB domain containing 4 increases response to substance ISO ZBTB4 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:54,480,698...54,501,492
Ensembl chr10:54,485,071...54,501,492 		JBrowse link
diethyl malate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle affects expression ISO diethyl malate affects the expression of ACTA2 mRNA CTD PMID:24814887 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 affects expression ISO diethyl malate affects the expression of ACTC1 mRNA CTD PMID:24814887 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actn3 actinin alpha 3 affects expression ISO diethyl malate affects the expression of ACTN3 mRNA CTD PMID:24814887 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Adcy1 adenylate cyclase 1 affects expression ISO diethyl malate affects the expression of ADCY1 mRNA CTD PMID:24814887 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide affects expression ISO diethyl malate affects the expression of ADH1 mRNA CTD PMID:24814887 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Agt angiotensinogen affects expression ISO diethyl malate affects the expression of AGT mRNA CTD PMID:24814887 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO diethyl malate results in increased expression of ANGPTL4 mRNA CTD PMID:38498338 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO diethyl malate results in increased expression of ASF1B mRNA CTD PMID:38498338 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 increases expression ISO diethyl malate results in increased expression of ATP6V1B2 mRNA CTD PMID:38498338 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO diethyl malate results in increased expression of BAG3 mRNA CTD PMID:38498338 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor increases expression ISO diethyl malate results in increased expression of BCAS2 mRNA CTD PMID:38498338 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO diethyl malate results in increased expression of BCL2L11 mRNA CTD PMID:38498338 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Brd2 bromodomain containing 2 increases expression ISO diethyl malate results in increased expression of BRD2 mRNA CTD PMID:38498338 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388 		JBrowse link
G C3 complement C3 affects expression ISO diethyl malate affects the expression of C3 mRNA CTD PMID:24814887 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 affects expression ISO diethyl malate affects the expression of CACNB2 mRNA CTD PMID:24814887 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 affects expression ISO diethyl malate affects the expression of CACNB4 mRNA CTD PMID:24814887 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
affects expression		 ISO S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CAMK2A mRNA] CTD PMID:24814887 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Casp3 caspase 3 increases expression ISO diethyl malate results in increased expression of CASP3 mRNA CTD PMID:38498338 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cbr2 carbonyl reductase 2 affects expression ISO diethyl malate affects the expression of CBR2 mRNA CTD PMID:24814887 NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 affects expression
increases expression		 ISO diethyl malate affects the expression of CCL20 mRNA
diethyl malate results in increased expression of CCL20 mRNA		 CTD PMID:24814887 PMID:38498338 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 affects expression ISO diethyl malate affects the expression of CCL7 mRNA CTD PMID:24814887 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 affects expression ISO diethyl malate affects the expression of CCL6 mRNA CTD PMID:24814887 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO diethyl malate results in increased expression of CTGF mRNA CTD PMID:38498338 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO diethyl malate results in increased expression of CCNE2 mRNA CTD PMID:38498338 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO diethyl malate results in increased expression of CDK5R1 mRNA CTD PMID:38498338 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO diethyl malate results in increased expression of CHAC1 mRNA CTD PMID:38498338 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression ISO diethyl malate results in increased expression of CIDEC mRNA CTD PMID:38498338 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO diethyl malate results in increased expression of CKS2 mRNA CTD PMID:38498338 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO diethyl malate results in increased expression of CLK1 mRNA CTD PMID:38498338 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain affects expression ISO diethyl malate affects the expression of COL11A1 mRNA CTD PMID:24814887 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col2a1 collagen type II alpha 1 chain affects expression ISO diethyl malate affects the expression of COL2A1 mRNA CTD PMID:24814887 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col3a1 collagen type III alpha 1 chain affects expression ISO diethyl malate affects the expression of COL3A1 mRNA CTD PMID:24814887 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain affects expression ISO diethyl malate affects the expression of COL6A1 mRNA CTD PMID:24814887 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Comp cartilage oligomeric matrix protein affects expression ISO diethyl malate affects the expression of COMP mRNA CTD PMID:24814887 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO diethyl malate results in increased expression of CSRNP1 mRNA CTD PMID:38498338 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 affects expression
multiple interactions		 ISO diethyl malate affects the expression of CXCL12 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CXCL12 mRNA]		 CTD PMID:24814887 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects expression ISO diethyl malate affects the expression of CXCL1 mRNA CTD PMID:24814887 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 affects expression ISO diethyl malate affects the expression of CXCL5 mRNA CTD PMID:24814887 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression ISO diethyl malate affects the expression of CYP2J9 mRNA CTD PMID:24814887 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO diethyl malate results in increased expression of CYP4F3 mRNA CTD PMID:38498338 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Dapk2 death-associated protein kinase 2 affects expression ISO diethyl malate affects the expression of DAPK2 mRNA CTD PMID:24814887 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO diethyl malate results in increased expression of DDIT3 mRNA CTD PMID:38498338 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 affects expression ISO diethyl malate affects the expression of DHRS3 mRNA CTD PMID:24814887 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhx58 DEXH-box helicase 58 affects expression ISO diethyl malate affects the expression of DHX58 mRNA CTD PMID:24814887 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO diethyl malate results in increased expression of DNAJB4 mRNA CTD PMID:38498338 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Edar ectodysplasin-A receptor affects expression ISO diethyl malate affects the expression of EDAR mRNA CTD PMID:24814887 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G Ednra endothelin receptor type A affects expression ISO diethyl malate affects the expression of EDNRA mRNA CTD PMID:24814887 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Emg1 EMG1 N1-specific pseudouridine methyltransferase increases expression ISO diethyl malate results in increased expression of EMG1 mRNA CTD PMID:38498338 NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540 		JBrowse link
G Eno2 enolase 2 increases expression ISO diethyl malate results in increased expression of ENO2 mRNA CTD PMID:38498338 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Epas1 endothelial PAS domain protein 1 affects expression ISO diethyl malate affects the expression of EPAS1 mRNA CTD PMID:24814887 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epha7 Eph receptor A7 affects expression ISO diethyl malate affects the expression of EPHA7 mRNA CTD PMID:24814887 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Ephb2 Eph receptor B2 affects expression ISO diethyl malate affects the expression of EPHB2 mRNA CTD PMID:24814887 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Ephb6 Eph receptor B6 affects expression ISO diethyl malate affects the expression of EPHB6 mRNA CTD PMID:24814887 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230 		JBrowse link
G Fam83d family with sequence similarity 83, member D increases expression ISO diethyl malate results in increased expression of FAM83D mRNA CTD PMID:38498338 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fgf10 fibroblast growth factor 10 affects expression ISO diethyl malate affects the expression of FGF10 mRNA CTD PMID:24814887 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf18 fibroblast growth factor 18 multiple interactions
affects expression		 ISO S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of FGF18 mRNA] CTD PMID:24814887 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects expression ISO diethyl malate affects the expression of FGFR2 mRNA CTD PMID:24814887 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO diethyl malate results in increased expression of FOSL1 mRNA CTD PMID:38498338 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fst follistatin affects expression ISO diethyl malate affects the expression of FST mRNA CTD PMID:24814887 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Fzd2 frizzled class receptor 2 affects expression ISO diethyl malate affects the expression of FZD2 mRNA CTD PMID:24814887 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Fzd7 frizzled class receptor 7 affects expression ISO diethyl malate affects the expression of FZD7 mRNA CTD PMID:24814887 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO diethyl malate results in increased expression of G6PD mRNA CTD PMID:38498338 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression ISO diethyl malate affects the expression of GCLC mRNA CTD PMID:24814887 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
affects expression		 ISO S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA] CTD PMID:24814887 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO diethyl malate results in increased expression of GCNT3 mRNA CTD PMID:38498338 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Ggt6 gamma-glutamyl transferase 6 affects expression ISO diethyl malate affects the expression of GGT6 mRNA CTD PMID:24814887 NCBI chr10:57,051,977...57,054,900
Ensembl chr10:57,051,825...57,067,260 		JBrowse link
G Gli2 GLI family zinc finger 2 affects expression ISO diethyl malate affects the expression of GLI2 mRNA CTD PMID:24814887 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gnao1 G protein subunit alpha o1 affects expression ISO diethyl malate affects the expression of GNAO1 mRNA CTD PMID:24814887 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gng7 G protein subunit gamma 7 affects expression ISO diethyl malate affects the expression of GNG7 mRNA CTD PMID:24814887 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240 		JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 increases expression ISO diethyl malate results in increased expression of GNPDA1 mRNA CTD PMID:38498338 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO diethyl malate results in increased expression of GPAT3 mRNA CTD PMID:38498338 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gsr glutathione-disulfide reductase affects expression ISO diethyl malate affects the expression of GSR mRNA CTD PMID:24814887 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase multiple interactions
affects expression		 ISO S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSS mRNA] CTD PMID:24814887 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 affects expression
multiple interactions		 ISO diethyl malate affects the expression of GSTA1 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSTA1 mRNA]		 CTD PMID:24814887 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 affects expression ISO diethyl malate affects the expression of GUCY1A1 mRNA CTD PMID:24814887 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 affects expression ISO diethyl malate affects the expression of GUCY1B1 mRNA CTD PMID:24814887 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G H2ac4 H2A clustered histone 4 increases expression ISO diethyl malate results in increased expression of HIST1H2AC mRNA CTD PMID:38498338 NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase affects expression ISO diethyl malate affects the expression of HCK mRNA CTD PMID:24814887 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693 		JBrowse link
G Hgf hepatocyte growth factor affects expression ISO diethyl malate affects the expression of HGF mRNA CTD PMID:24814887 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO diethyl malate results in increased expression of HIST1H2BD mRNA CTD PMID:38498338 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO diethyl malate results in increased expression of HMGCS2 mRNA CTD PMID:38498338 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO diethyl malate results in increased expression of HMMR mRNA CTD PMID:38498338 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO diethyl malate results in increased expression of HMOX1 mRNA CTD PMID:38498338 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO diethyl malate results in increased expression of HSP90AA1 mRNA CTD PMID:38498338 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO diethyl malate results in increased expression of HSPA1A mRNA CTD PMID:38498338 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO diethyl malate results in increased expression of HSPA1B mRNA CTD PMID:38498338 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO diethyl malate results in increased expression of HSPA2 mRNA CTD PMID:38498338 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO diethyl malate results in increased expression of HSPA8 mRNA CTD PMID:38498338 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO diethyl malate results in increased expression of IFRD1 mRNA CTD PMID:38498338 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Igf1 insulin-like growth factor 1 affects expression ISO diethyl malate affects the expression of IGF1 mRNA CTD PMID:24814887 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO diethyl malate results in increased expression of IGFBP3 mRNA CTD PMID:38498338 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il15 interleukin 15 affects expression ISO diethyl malate affects the expression of IL15 mRNA CTD PMID:24814887 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il18 interleukin 18 affects expression ISO diethyl malate affects the expression of IL18 mRNA CTD PMID:24814887 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 affects expression ISO diethyl malate affects the expression of IRAG1 mRNA CTD PMID:24814887 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176 		JBrowse link
G Irf7 interferon regulatory factor 7 affects expression ISO diethyl malate affects the expression of IRF7 mRNA CTD PMID:24814887 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO diethyl malate affects the expression of ISG15 mRNA CTD PMID:24814887 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itga11 integrin subunit alpha 11 affects expression ISO diethyl malate affects the expression of ITGA11 mRNA CTD PMID:24814887 NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407 		JBrowse link
G Itga3 integrin subunit alpha 3 affects expression ISO diethyl malate affects the expression of ITGA3 mRNA CTD PMID:24814887 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression ISO diethyl malate results in increased expression of JMJD6 mRNA CTD PMID:38498338 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 affects expression ISO diethyl malate affects the expression of KCNMB4 mRNA CTD PMID:24814887 NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278 		JBrowse link
G Lama1 laminin subunit alpha 1 affects expression ISO diethyl malate affects the expression of LAMA1 mRNA CTD PMID:24814887 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478 		JBrowse link
G Lama4 laminin subunit alpha 4 affects expression ISO diethyl malate affects the expression of LAMA4 mRNA CTD PMID:24814887 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO diethyl malate results in increased expression of MAFF mRNA CTD PMID:38498338 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO diethyl malate results in increased expression of MAFG mRNA CTD PMID:38498338 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO diethyl malate results in increased expression of MAP1LC3B mRNA CTD PMID:38498338 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation
multiple interactions		 ISO diethyl malate affects the phosphorylation of MAPK1 protein
S-ethyl glutathione inhibits the reaction [diethyl malate affects the phosphorylation of MAPK1 protein]		 CTD PMID:24814887 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation
multiple interactions		 ISO diethyl malate affects the phosphorylation of MAPK3 protein
S-ethyl glutathione inhibits the reaction [diethyl malate affects the phosphorylation of MAPK3 protein]		 CTD PMID:24814887 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO diethyl malate results in increased expression of MMP1 mRNA CTD PMID:38498338 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO diethyl malate results in increased expression of MMP3 mRNA CTD PMID:38498338 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Myl4 myosin, light chain 4 increases expression ISO diethyl malate results in increased expression of MYL4 mRNA CTD PMID:38498338 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363 		JBrowse link
G Myl9 myosin light chain 9 affects expression ISO diethyl malate affects the expression of MYL9 mRNA CTD PMID:24814887 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO diethyl malate results in increased expression of NDRG1 mRNA CTD PMID:38498338 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Odc1 ornithine decarboxylase 1 affects expression ISO diethyl malate affects the expression of ODC1 mRNA CTD PMID:24814887 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression ISO diethyl malate results in increased expression of OSGIN1 mRNA CTD PMID:38498338 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516 		JBrowse link
G Pdgfb platelet derived growth factor subunit B affects expression
multiple interactions		 ISO diethyl malate affects the expression of PDGFB mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of PDGFB mRNA]		 CTD PMID:24814887 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfd platelet derived growth factor D affects expression ISO diethyl malate affects the expression of PDGFD mRNA CTD PMID:24814887 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pf4 platelet factor 4 affects expression ISO diethyl malate affects the expression of PF4 mRNA CTD PMID:24814887 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 increases expression ISO diethyl malate results in increased expression of PFKFB4 mRNA CTD PMID:38498338 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 affects expression ISO diethyl malate affects the expression of PIK3IP1 mRNA CTD PMID:24814887 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Plin2 perilipin 2 increases expression ISO diethyl malate results in increased expression of PLIN2 mRNA CTD PMID:38498338 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plxnc1 plexin C1 affects expression ISO diethyl malate affects the expression of PLXNC1 mRNA CTD PMID:24814887 NCBI chr 7:29,390,038...29,543,985
Ensembl chr 7:29,390,048...29,543,779 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO diethyl malate results in increased expression of PPP1R15A mRNA CTD PMID:38498338 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 affects expression ISO diethyl malate affects the expression of PRKG1 mRNA CTD PMID:24814887 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Ptgis prostaglandin I2 synthase affects expression ISO diethyl malate affects the expression of PTGIS mRNA CTD PMID:24814887 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ramp2 receptor activity modifying protein 2 affects expression ISO diethyl malate affects the expression of RAMP2 mRNA CTD PMID:24814887 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Rgs3 regulator of G-protein signaling 3 affects expression ISO diethyl malate affects the expression of RGS3 mRNA CTD PMID:24814887 NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894 		JBrowse link
G Rig1 RNA sensor RIG-1 affects expression ISO diethyl malate affects the expression of RIGI mRNA CTD PMID:24814887 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO diethyl malate affects the expression of H2-DMB1 mRNA CTD PMID:24814887 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO diethyl malate affects the expression of H2-M3 mRNA CTD PMID:24814887 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 affects expression ISO diethyl malate affects the expression of RUNX1T1 mRNA CTD PMID:24814887 NCBI chr 5:27,187,674...27,338,070
Ensembl chr 5:27,187,551...27,335,592 		JBrowse link
G Sema3b semaphorin 3B affects expression ISO diethyl malate affects the expression of SEMA3B mRNA CTD PMID:24814887 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919 		JBrowse link
G Sema4g semaphorin 4G affects expression ISO diethyl malate affects the expression of SEMA4G mRNA CTD PMID:24814887 NCBI chr 1:243,849,979...243,865,343
Ensembl chr 1:243,853,854...243,865,341 		JBrowse link
G Sema5a semaphorin 5A affects expression ISO diethyl malate affects the expression of SEMA5A mRNA CTD PMID:24814887 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084 		JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO diethyl malate results in increased expression of SERTAD1 mRNA CTD PMID:38498338 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO diethyl malate results in increased expression of SLC7A11 mRNA CTD PMID:38498338 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO diethyl malate results in increased expression of SRXN1 mRNA CTD PMID:38498338 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 affects expression ISO diethyl malate affects the expression of STAT1 mRNA CTD PMID:24814887 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 increases expression ISO diethyl malate results in increased expression of TACC3 mRNA CTD PMID:38498338 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219 		JBrowse link
G Tes testin LIM domain protein increases expression ISO diethyl malate results in increased expression of TES mRNA CTD PMID:38498338 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 affects expression
multiple interactions		 ISO diethyl malate affects the expression of TGFB2 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of TGFB2 mRNA]		 CTD PMID:24814887 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Thbs1 thrombospondin 1 affects expression ISO diethyl malate affects the expression of THBS1 mRNA CTD PMID:24814887 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 affects expression ISO diethyl malate affects the expression of THBS2 mRNA CTD PMID:24814887 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Tnc tenascin C affects expression ISO diethyl malate affects the expression of TNC mRNA CTD PMID:24814887 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B affects expression ISO diethyl malate affects the expression of TNFRSF11B mRNA CTD PMID:24814887 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type affects expression ISO diethyl malate affects the expression of TNNT1 mRNA CTD PMID:24814887 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO diethyl malate results in increased expression of TRIB3 mRNA CTD PMID:38498338 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Tslp thymic stromal lymphopoietin affects expression ISO diethyl malate affects the expression of TSLP mRNA CTD PMID:24814887 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO diethyl malate results in increased expression of VEGFA mRNA CTD PMID:38498338 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Zbtb21 zinc finger and BTB domain containing 21 increases expression ISO diethyl malate results in increased expression of ZBTB21 mRNA CTD PMID:38498338 NCBI chr11:37,312,337...37,327,040
Ensembl chr11:37,312,378...37,326,996 		JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO diethyl malate results in increased expression of ZNF274 mRNA CTD PMID:38498338 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086 		JBrowse link
G Zfp367 zinc finger protein 367 increases expression ISO diethyl malate results in increased expression of ZNF367 mRNA CTD PMID:38498338 NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287 		JBrowse link
hydrocortisone succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2 CTD PMID:18347083 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP3A4 CTD PMID:18347083 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G F2 coagulation factor II, thrombin affects expression ISO hydrocortisone hemisuccinate affects the expression of F2 protein CTD PMID:12542493 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Il18 interleukin 18 decreases secretion ISO hydrocortisone hemisuccinate results in decreased secretion of IL18 protein CTD PMID:20421217 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta decreases secretion ISO hydrocortisone hemisuccinate results in decreased secretion of IL1B protein CTD PMID:20421217 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases secretion ISO hydrocortisone hemisuccinate results in decreased secretion of IL6 protein CTD PMID:20421217 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO hydrocortisone hemisuccinate results in decreased secretion of TNF protein CTD PMID:20421217 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
malathion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acbd5 acyl-CoA binding domain containing 5 increases expression ISO Malathion results in increased expression of ACBD5 mRNA CTD PMID:37047231 NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215 		JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity		 ISO
EXP		 [Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]
[Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in increased activity of ACHE protein; Taurine inhibits the reaction [Malathion results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]		 CTD PMID:2380476 PMID:4859365 PMID:14713564 PMID:18617161 PMID:19429256 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acot6 acyl-CoA thioesterase 6 decreases expression ISO Malathion results in decreased expression of ACOT6 mRNA CTD PMID:37047231 NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression ISO Malathion results in decreased expression of ACSM1 mRNA CTD PMID:17311802 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495 		JBrowse link
G Adam11 ADAM metallopeptidase domain 11 increases methylation ISO Malathion results in increased methylation of ADAM11 promoter CTD PMID:37047231 NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562 		JBrowse link
G Adam32 ADAM metallopeptidase domain 32 decreases expression ISO Malathion results in decreased expression of ADAM32 mRNA CTD PMID:37047231 NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161 		JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 decreases expression ISO Malathion results in decreased expression of ADAMTS12 mRNA CTD PMID:37047231 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 decreases expression ISO Malathion results in decreased expression of ADAMTS20 mRNA CTD PMID:37047231 NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777 		JBrowse link
G Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 increases expression ISO Malathion results in increased expression of ADAMTS6 mRNA CTD PMID:37047231 NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298 		JBrowse link
G Add3 adducin 3 increases expression EXP Malathion results in increased expression of ADD3 mRNA CTD PMID:19784758 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Adm adrenomedullin increases expression ISO Malathion results in increased expression of ADM mRNA CTD PMID:37047231 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO Malathion results in increased expression of ADRA2A mRNA CTD PMID:37047231 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Aff1 ALF transcription elongation factor 1 increases expression ISO Malathion results in increased expression of AFF1 mRNA mutant form CTD PMID:28624474 NCBI chr14:5,861,188...6,024,196
Ensembl chr14:5,863,961...6,024,729 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [prothioconazole co-treated with terbutylazine co-treated with bitertanol co-treated with cypermethrin co-treated with Malathion] results in increased activity of AHR protein CTD PMID:25684042 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Malathion results in increased expression of AKR1C1 mRNA CTD PMID:16079077 PMID:18214805 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Malathion results in increased expression of AKR1C2 mRNA CTD PMID:16079077 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 decreases expression ISO Malathion results in decreased expression of AKR1E2 mRNA CTD PMID:37047231 NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441 		JBrowse link
G Alkal2 ALK and LTK ligand 2 increases expression ISO Malathion results in increased expression of ALKAL2 mRNA CTD PMID:37047231 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases activity
multiple interactions		 EXP Malathion results in increased activity of ALPL protein
thymoquinone inhibits the reaction [Malathion results in increased activity of ALPL protein]		 CTD PMID:33510276 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Amot angiomotin decreases expression ISO Malathion results in decreased expression of AMOT mRNA CTD PMID:37047231 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Malathion results in decreased expression of ANGPTL2 mRNA CTD PMID:37047231 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases methylation
increases expression		 ISO Malathion results in decreased methylation of ANGPTL4 promoter
Malathion results in increased expression of ANGPTL4 mRNA		 CTD PMID:37047231 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ank1 ankyrin 1 decreases expression ISO Malathion results in decreased expression of ANK1 mRNA CTD PMID:37047231 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ankrd55 ankyrin repeat domain 55 increases expression ISO Malathion results in increased expression of ANKRD55 mRNA CTD PMID:37047231 NCBI chr 2:43,883,877...43,983,820
Ensembl chr 2:43,883,857...43,983,680 		JBrowse link
G Aplf aprataxin and PNKP like factor decreases expression ISO Malathion results in decreased expression of APLF mRNA CTD PMID:37047231 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Aqp12a aquaporin 12A decreases expression ISO Malathion results in decreased expression of AQP12A mRNA CTD PMID:37047231 NCBI chr 9:93,554,527...93,560,011
Ensembl chr 9:93,554,527...93,560,011 		JBrowse link
G Aqp9 aquaporin 9 increases expression ISO Malathion results in increased expression of AQP9 mRNA CTD PMID:37047231 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression		 ISO
EXP		 [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein
Malathion results in decreased expression of AR mRNA		 CTD PMID:23871939 PMID:36336997 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Armc3 armadillo repeat containing 3 decreases expression ISO Malathion results in decreased expression of ARMC3 mRNA CTD PMID:37047231 NCBI chr17:81,814,087...81,917,534
Ensembl chr17:81,832,518...81,917,531 		JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression ISO Malathion results in decreased expression of ARNT2 mRNA CTD PMID:37047231 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153 		JBrowse link
G Asic5 acid sensing ion channel subunit family member 5 increases expression ISO Malathion results in increased expression of ASIC5 mRNA CTD PMID:37047231 NCBI chr 2:167,307,984...167,336,812
Ensembl chr 2:167,307,984...167,336,812 		JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 decreases expression ISO Malathion results in decreased expression of ATP2B3 mRNA CTD PMID:37047231 NCBI chr  X:151,216,483...151,289,069
Ensembl chr  X:151,216,507...151,286,775 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 decreases expression ISO Malathion results in decreased expression of B4GALT1 mRNA CTD PMID:32069766 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G B9d1 B9 domain containing 1 decreases expression ISO Malathion results in decreased expression of B9D1 mRNA CTD PMID:37047231 NCBI chr10:46,186,222...46,196,309
Ensembl chr10:46,186,691...46,196,008 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions		 EXP
ISO		 Malathion results in decreased expression of BAX mRNA
Malathion results in increased expression of BAX protein
crocin inhibits the reaction [Malathion results in increased expression of BAX protein]
Plant Extracts inhibits the reaction [Malathion results in increased expression of BAX protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of BAX protein]
Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein]		 CTD PMID:23774768 PMID:30769050 PMID:32120800 PMID:35274200 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity
decreases activity		 ISO
EXP		 Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of BCHE protein]
Malathion results in increased activity of BCHE protein		 CTD PMID:17364237 PMID:18617161 PMID:21983245 PMID:25180440 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions		 EXP
ISO		 Malathion results in decreased expression of BCL2 mRNA
Malathion results in increased expression of BCL2 mRNA
Malathion results in increased expression of BCL2 protein
Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein]		 CTD PMID:23774768 PMID:30673264 PMID:30769050 PMID:32120800 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Pesticides results in increased abundance of Malathion metabolite] which results in decreased secretion of BDNF protein; [Pesticides results in increased abundance of Malathion metabolite] which results in increased methylation of BDNF gene CTD PMID:35292247 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions		 EXP Malathion results in increased expression of BIRC5 protein
Rosmarinic Acid inhibits the reaction [Malathion results in increased expression of BIRC5 protein]; thymoquinone inhibits the reaction [Malathion results in increased expression of BIRC5 protein]		 CTD PMID:33510276 PMID:34262720 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger increases expression ISO Malathion results in increased expression of BMI1 mRNA CTD PMID:32069766 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Brd7 bromodomain containing 7 increases expression ISO Malathion results in increased expression of BRD7 mRNA CTD PMID:18214912 NCBI chr19:18,708,792...18,737,497
Ensembl chr19:18,709,022...18,737,494 		JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta increases expression ISO Malathion results in increased expression of BSND mRNA CTD PMID:37047231 NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:121,251,774...121,260,571 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO Malathion results in decreased expression of BTG1 mRNA CTD PMID:32069766 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Malathion results in decreased expression of BUB1 mRNA CTD PMID:16079077 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G C16h10orf53 similar to human chromosome 10 open reading frame 53 decreases expression ISO Malathion results in decreased expression of C10ORF53 mRNA CTD PMID:37047231 NCBI chr16:7,634,207...7,644,876
Ensembl chr16:7,634,207...7,644,876 		JBrowse link
G C1ql2 complement C1q like 2 decreases expression ISO Malathion results in decreased expression of C1QL2 mRNA CTD PMID:37047231 NCBI chr13:31,471,150...31,472,685
Ensembl chr13:31,471,150...31,472,689 		JBrowse link
G C2h3orf80 similar to human chromosome 3 open reading frame 80 decreases expression ISO Malathion results in decreased expression of C3ORF80 mRNA CTD PMID:37047231 NCBI chr 2:153,125,312...153,128,124
Ensembl chr 2:153,125,676...153,126,419 		JBrowse link
G C3h11orf96 similar to human chromosome 11 open reading frame 96 increases expression ISO Malathion results in increased expression of C11ORF96 mRNA CTD PMID:37047231 NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523 		JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 increases expression ISO Malathion results in increased expression of C15ORF48 mRNA CTD PMID:37047231 NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006 		JBrowse link
G C5h8orf34 similar to human chromosome 8 open reading frame 34 decreases expression ISO Malathion results in decreased expression of C8ORF34 mRNA CTD PMID:37047231 NCBI chr 5:7,237,968...7,777,119
Ensembl chr 5:7,238,853...7,776,769 		JBrowse link
G C7h12orf54 similar to human chromosome 12 open reading frame 54 decreases expression ISO Malathion results in decreased expression of C12ORF54 mRNA CTD PMID:37047231 NCBI chr 7:129,529,811...129,548,676 JBrowse link
G Cabp7 calcium binding protein 7 decreases expression ISO Malathion results in decreased expression of CABP7 mRNA CTD PMID:37047231 NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression ISO Malathion results in increased expression of CACNA1C mRNA CTD PMID:37047231 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA] CTD PMID:28385489 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Capn8 calpain 8 decreases expression ISO Malathion results in decreased expression of CAPN8 mRNA CTD PMID:37047231 NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146 		JBrowse link
G Cartpt CART prepropeptide increases expression ISO Malathion results in increased expression of CARTPT mRNA CTD PMID:37047231 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
multiple interactions
increases expression		 ISO
EXP		 Malathion results in increased activity of CASP3 protein
Malathion results in increased cleavage of CASP3 protein
Malathion results in increased activity of and results in increased cleavage of CASP3 protein; Metoclopramide inhibits the reaction [Malathion results in increased activity of and results in increased cleavage of CASP3 protein]
Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]
Malathion results in increased expression of CASP3 mRNA
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; Levodopa inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]		 CTD PMID:12505448 PMID:19815060 PMID:21628957 PMID:27941166 PMID:29027213 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 decreases expression ISO Malathion results in decreased expression of CASP4 mRNA CTD PMID:32069766 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 increases activity ISO Malathion results in increased activity of CASP8 protein CTD PMID:12505448 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
multiple interactions
increases expression		 ISO
EXP		 Malathion results in increased activity of CASP9 protein
Malathion results in increased cleavage of CASP9 protein
Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]; Levodopa inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]		 CTD PMID:12505448 PMID:21628957 PMID:27941166 PMID:30769050 PMID:35274200 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
increases activity		 EXP
ISO		 [Dimethoate co-treated with Malathion] results in increased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; Pentoxifylline inhibits the reaction [Malathion results in increased activity of CAT protein]; Taurine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
Malathion results in decreased expression of CAT protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]
[Malathion co-treated with 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide] results in increased activity of CAT protein; [Malathion co-treated with pralidoxime] results in increased activity of CAT protein; lavender oil inhibits the reaction [Malathion results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Malathion results in decreased activity of CAT protein]; Polyphenols inhibits the reaction [Malathion results in decreased activity of CAT protein]		 CTD PMID:11834209 PMID:18655177 PMID:19429256 PMID:20194575 PMID:21628957 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbfb core-binding factor subunit beta increases expression ISO Malathion results in increased expression of CBFB mRNA CTD PMID:32069766 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Ccdc126 coiled-coil domain containing 126 increases expression ISO Malathion results in increased expression of CCDC126 mRNA CTD PMID:37047231 NCBI chr 4:78,297,625...78,318,655
Ensembl chr 4:78,297,551...78,318,655 		JBrowse link
G Cck cholecystokinin increases expression EXP Malathion results in increased expression of CCK mRNA CTD PMID:19784758 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases expression ISO Malathion results in increased expression of CCL1 mRNA CTD PMID:37047231 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO Malathion results in increased expression of CCL19 mRNA CTD PMID:37047231 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Malathion results in increased expression of CCL20 mRNA CTD PMID:37047231 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Malathion results in increased expression of CCL3 mRNA CTD PMID:37047231 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Malathion results in increased expression of CCL7 mRNA CTD PMID:37047231 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccm2l CCM2 like scaffold protein increases expression ISO Malathion results in increased expression of CCM2L mRNA CTD PMID:37047231 NCBI chr 3:141,533,470...141,549,136
Ensembl chr 3:141,533,511...141,549,140 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Malathion results in decreased expression of CCNA2 protein CTD PMID:30769050 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Malathion results in decreased expression of CCNB1 protein CTD PMID:30769050 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Malathion results in decreased expression of CCNE1 protein CTD PMID:30769050 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 increases expression ISO Malathion results in increased expression of CCSER1 mRNA CTD PMID:37047231 NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786 		JBrowse link
G Cd14 CD14 molecule decreases expression ISO Malathion results in decreased expression of CD14 mRNA CTD PMID:32069766 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Malathion results in increased expression of CD274 mRNA CTD PMID:37047231 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd36 CD36 molecule increases expression ISO Malathion results in increased expression of CD36 mRNA CTD PMID:32069766 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd5 Cd5 molecule decreases expression ISO Malathion results in decreased expression of CD5 mRNA CTD PMID:32069766 NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313 		JBrowse link
G Cd69 Cd69 molecule increases expression ISO Malathion results in increased expression of CD69 mRNA CTD PMID:37047231 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Malathion results in decreased expression of CDC20 mRNA CTD PMID:18214805 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdk15 cyclin-dependent kinase 15 increases expression ISO Malathion results in increased expression of CDK15 mRNA CTD PMID:37047231 NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
increases expression		 ISO Malathion results in decreased expression of CDK2 protein
Malathion results in increased expression of CDK2 mRNA		 CTD PMID:30769050 PMID:32069766 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO Malathion results in increased expression of CEBPG mRNA CTD PMID:32069766 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569 		JBrowse link
G Cenpf centromere protein F decreases expression ISO Malathion results in decreased expression of CENPF mRNA CTD PMID:16079077 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Malathion results in increased expression of CES1 mRNA CTD PMID:17311802 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfap157 cilia and flagella associated protein 157 decreases expression ISO Malathion results in decreased expression of CFAP157 mRNA CTD PMID:37047231 NCBI chr 3:16,066,521...16,073,504
Ensembl chr 3:16,066,521...16,073,495 		JBrowse link
G Cfap91 cilia and flagella associated protein 91 decreases expression ISO Malathion results in decreased expression of CFAP91 mRNA CTD PMID:37047231 NCBI chr11:62,413,613...62,457,281
Ensembl chr11:62,413,602...62,457,293 		JBrowse link
G Cfb complement factor B increases expression ISO Malathion results in increased expression of CFB mRNA CTD PMID:37047231 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO Malathion results in increased expression of CH25H mRNA CTD PMID:37047231 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Cldn12 claudin 12 increases expression ISO Malathion results in increased expression of CLDN12 mRNA CTD PMID:37047231 NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801 		JBrowse link
G Cldn22 claudin 22 decreases expression ISO Malathion results in decreased expression of CLDN22 mRNA CTD PMID:37047231 NCBI chr16:44,422,344...44,423,370
Ensembl chr16:44,422,345...44,423,354 		JBrowse link
G Cldn5 claudin 5 multiple interactions
decreases expression		 EXP [Malathion co-treated with Lead] results in decreased expression of CLDN5 protein
Malathion results in decreased expression of CLDN5 protein		 CTD PMID:20970449 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cma1 chymase 1 decreases expression ISO Malathion results in decreased expression of CMA1 mRNA CTD PMID:37047231 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233 		JBrowse link
G Cntn4 contactin 4 increases expression ISO Malathion results in increased expression of CNTN4 mRNA CTD PMID:37047231 NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO Malathion results in increased expression of COL1A2 mRNA CTD PMID:32069766 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cpne9 copine family member 9 decreases expression ISO Malathion results in decreased expression of CPNE9 mRNA CTD PMID:37047231 NCBI chr 4:146,429,961...146,454,335
Ensembl chr 4:146,430,792...146,454,333 		JBrowse link
G Cpz carboxypeptidase Z decreases expression ISO Malathion results in decreased expression of CPZ mRNA CTD PMID:37047231 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
decreases expression		 EXP caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:20233601 PMID:25404496 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crisp3 cysteine-rich secretory protein 3 decreases expression ISO Malathion results in decreased expression of CRISP3 mRNA CTD PMID:37047231 NCBI chr 9:20,432,051...20,472,663
Ensembl chr 9:20,450,908...20,472,658 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression EXP Malathion results in decreased expression of CRISPLD2 mRNA CTD PMID:19784758 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression EXP
ISO		 Malathion results in increased expression of CSF2 protein
Malathion results in increased expression of CSF2 mRNA		 CTD PMID:34778934 PMID:37047231 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Malathion results in increased expression of CSF3 mRNA CTD PMID:37047231 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ctsd cathepsin D increases expression ISO Malathion results in increased expression of CTSD protein CTD PMID:8812242 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Malathion results in increased expression of CXCL11 mRNA CTD PMID:37047231 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
increases expression		 ISO Plant Extracts inhibits the reaction [Malathion results in increased expression of CYBB protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of CYBB protein] CTD PMID:32120800 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions		 ISO Malathion results in decreased expression of CYP11A1 mRNA
lavender oil inhibits the reaction [Malathion results in decreased expression of CYP11A1 mRNA]		 CTD PMID:30409133 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA CTD PMID:23954766 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression		 ISO CYP1A2 protein affects the metabolism of Malathion
Malathion results in increased expression of CYP1A2 mRNA		 CTD PMID:15557345 PMID:22310298 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Malathion results in increased expression of CYP27B1 mRNA CTD PMID:37047231 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
multiple interactions
increases expression
decreases activity		 ISO CYP2B6 protein affects the metabolism of Malathion
Malathion promotes the reaction [isomalathion results in increased expression of CYP2B6 mRNA]
Malathion results in increased expression of CYP2B6 mRNA
Malathion results in decreased activity of CYP2B6 protein		 CTD PMID:15557345 PMID:22310298 PMID:24333466 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity		 ISO Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
Malathion results in decreased activity of CYP2E1 protein		 CTD PMID:22634058 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
affects metabolic processing		 ISO [Malathion co-treated with isomalathion] results in increased expression of CYP3A4 mRNA
Malathion results in increased expression of CYP3A4 mRNA
CYP3A4 protein affects the metabolism of Malathion		 CTD PMID:15557345 PMID:17110060 PMID:22310298 PMID:24333466 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
increases expression		 ISO CYP3A5 protein affects the metabolism of Malathion
Malathion results in increased expression of CYP3A5 mRNA		 CTD PMID:17110060 PMID:37047231 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Insecticides results in increased abundance of Malathion] which affects the methylation of CYP8B1 gene CTD PMID:34516295 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Dcn decorin increases expression ISO Malathion results in increased expression of DCN mRNA CTD PMID:37047231 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddc dopa decarboxylase affects binding
increases expression		 ISO Malathion binds to [DDC protein binds to Pyridoxal Phosphate]; Malathion binds to DDC protein
Malathion results in increased expression of DDC mRNA		 CTD PMID:35151785 PMID:37047231 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 decreases expression ISO Malathion results in decreased expression of DDR1 mRNA CTD PMID:37047231 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddx11 DEAD/H-box helicase 11 increases expression ISO Malathion results in increased expression of DDX11 mRNA CTD PMID:32069766 NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO Malathion results in decreased expression of DIO1 mRNA CTD PMID:37047231 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Disc1 DISC1 scaffold protein increases expression ISO Malathion results in increased expression of DISC1 mRNA CTD PMID:37047231 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 increases expression ISO Malathion results in increased expression of DKK2 mRNA CTD PMID:37047231 NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Malathion results in increased expression of DLG2 mRNA CTD PMID:37047231 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression EXP Malathion results in decreased expression of DNMT1 mRNA CTD PMID:36370973 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha affects expression EXP Malathion affects the expression of DNMT3A mRNA CTD PMID:36370973 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta affects expression EXP Malathion affects the expression of DNMT3B mRNA CTD PMID:36370973 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Doc2b double C2 domain beta decreases expression ISO Malathion results in decreased expression of DOC2B mRNA CTD PMID:37047231 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267 		JBrowse link
G Dsp desmoplakin increases expression ISO Malathion results in increased expression of DSP mRNA CTD PMID:37047231 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800 		JBrowse link
G Dspp dentin sialophosphoprotein decreases expression ISO Malathion results in decreased expression of DSPP mRNA CTD PMID:37047231 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Dtna dystrobrevin, alpha decreases expression ISO Malathion results in decreased expression of DTNA mRNA CTD PMID:37047231 NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261 		JBrowse link
G Duox1 dual oxidase 1 multiple interactions
increases expression		 ISO Plant Extracts inhibits the reaction [Malathion results in increased expression of DUOX1 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of DUOX1 protein] CTD PMID:32120800 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO Malathion results in decreased expression of DUSP1 mRNA CTD PMID:32069766 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO Malathion results in increased expression of DUSP5 mRNA CTD PMID:37047231 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 increases expression ISO Malathion results in increased expression of DVL1 mRNA CTD PMID:18204794 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 increases expression ISO Malathion results in increased expression of EBI3 mRNA CTD PMID:37047231 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Malathion results in increased expression of EDN1 mRNA CTD PMID:37047231 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednrb endothelin receptor type B decreases expression ISO Malathion results in decreased expression of EDNRB mRNA CTD PMID:37047231 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efcab9 EF-hand calcium binding domain 9 increases expression ISO Malathion results in increased expression of EFCAB9 mRNA CTD PMID:37047231 NCBI chr10:17,107,123...17,112,282
Ensembl chr10:17,107,123...17,112,289 		JBrowse link
G Ehbp1 EH domain binding protein 1 increases response to substance ISO EHBP1 gene SNP results in increased susceptibility to Malathion CTD PMID:23593118 NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332 		JBrowse link
G En1 engrailed homeobox 1 decreases expression ISO Malathion results in decreased expression of EN1 mRNA CTD PMID:37047231 NCBI chr13:31,750,892...31,756,477
Ensembl chr13:31,751,545...31,755,943 		JBrowse link
G Enkur enkurin, TRPC channel interacting protein increases expression ISO Malathion results in increased expression of ENKUR mRNA CTD PMID:37047231 NCBI chr17:83,690,105...83,714,756
Ensembl chr17:83,690,797...83,714,408 		JBrowse link
G Epha10 EPH receptor A10 increases expression ISO Malathion results in increased expression of EPHA10 mRNA CTD PMID:37047231 NCBI chr 5:137,139,588...137,175,637
Ensembl chr 5:137,140,735...137,174,157 		JBrowse link
G Epha4 Eph receptor A4 increases expression ISO Malathion results in increased expression of EPHA4 mRNA CTD PMID:32069766 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Malathion results in decreased expression of EPHX1 mRNA CTD PMID:17311802 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Epop elongin BC and polycomb repressive complex 2 associated protein increases expression ISO Malathion results in increased expression of EPOP mRNA CTD PMID:37047231 NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912 		JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO Malathion results in increased expression of EPS8L1 mRNA CTD PMID:32069766 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression ISO Malathion results in increased expression of ERBB4 mRNA CTD PMID:37047231 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Esr1 estrogen receptor 1 decreases activity ISO Malathion results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Etv6 ETS variant transcription factor 6 increases expression ISO Malathion results in increased expression of ETV6 mRNA mutant form CTD PMID:28624474 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Malathion results in increased expression of F3 mRNA CTD PMID:37047231 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam124a family with sequence similarity 124 member A increases expression ISO Malathion results in increased expression of FAM124A mRNA CTD PMID:37047231 NCBI chr15:36,799,836...36,855,062
Ensembl chr15:36,799,877...36,853,683 		JBrowse link
G Fam227b family with sequence similarity 227, member B decreases expression ISO Malathion results in decreased expression of FAM227B mRNA CTD PMID:37047231 NCBI chr 3:113,226,662...113,392,396
Ensembl chr 3:113,233,205...113,392,320 		JBrowse link
G Fam229b family with sequence similarity 229, member B decreases expression ISO Malathion results in decreased expression of FAM229B mRNA CTD PMID:37047231 NCBI chr20:42,538,853...42,552,355
Ensembl chr20:42,538,868...42,552,248 		JBrowse link
G Fgf22 fibroblast growth factor 22 decreases expression ISO Malathion results in decreased expression of FGF22 mRNA CTD PMID:37047231 NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486 		JBrowse link
G Fgf6 fibroblast growth factor 6 increases expression ISO Malathion results in increased expression of FGF6 mRNA CTD PMID:32069766 NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447 		JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 increases expression ISO Malathion results in increased expression of FGFBP1 mRNA CTD PMID:37047231 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Malathion results in increased expression of FGFR1 mRNA CTD PMID:32069766 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgg fibrinogen gamma chain decreases expression ISO Malathion results in decreased expression of FGG mRNA CTD PMID:37047231 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO Malathion results in increased expression of FILIP1L mRNA CTD PMID:37047231 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 increases expression ISO Malathion results in increased expression of FLT4 mRNA CTD PMID:37047231 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770 		JBrowse link
G Foxo1 forkhead box O1 decreases expression
increases methylation
multiple interactions		 EXP Malathion results in decreased expression of FOXO1 mRNA
Malathion results in increased methylation of FOXO1 promoter
[Malathion results in increased methylation of FOXO1 promoter] which results in decreased expression of FOXO1 mRNA		 CTD PMID:36370973 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo4 forkhead box O4 increases expression ISO Malathion results in increased expression of FOXO4 mRNA CTD PMID:32069766 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Fshr follicle stimulating hormone receptor increases expression ISO Malathion results in increased expression of FSHR mRNA CTD PMID:32069766 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases activity		 EXP [Malathion co-treated with Carbaryl] results in increased activity of G6PD protein; Plant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]
Malathion results in increased activity of G6PD protein		 CTD PMID:27214522 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gad1 glutamate decarboxylase 1 affects binding ISO Malathion binds to [GAD1 protein binds to Pyridoxal Phosphate]; Malathion binds to GAD1 protein CTD PMID:35151785 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 affects binding ISO Malathion binds to [GAD2 protein binds to Pyridoxal Phosphate]; Malathion binds to GAD2 protein CTD PMID:35151785 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 increases expression ISO Malathion results in increased expression of GALNT16 mRNA CTD PMID:37047231 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705 		JBrowse link
G Garin2 golgi associated RAB2 interactor family member 2 decreases expression ISO Malathion results in decreased expression of GARIN2 mRNA CTD PMID:37047231 NCBI chr 6:97,489,562...97,534,729
Ensembl chr 6:97,490,368...97,534,763 		JBrowse link
G Gas2 growth arrest-specific 2 increases expression ISO Malathion results in increased expression of GAS2 mRNA CTD PMID:37047231 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619 		JBrowse link
G Gata4 GATA binding protein 4 decreases expression ISO Malathion results in decreased expression of GATA4 mRNA CTD PMID:37047231 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO Malathion results in increased expression of GBP1 mRNA CTD PMID:37047231 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gbp3 guanylate binding protein 3 increases expression ISO Malathion results in increased expression of GBP3 mRNA CTD PMID:37047231 NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098 		JBrowse link
G Gbp5 guanylate binding protein 5 increases expression ISO Malathion results in increased expression of GBP5 mRNA CTD PMID:37047231 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Gk glycerol kinase multiple interactions
increases activity		 EXP Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein] CTD PMID:25449180 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gk2 glycerol kinase 2 decreases expression EXP Malathion results in decreased expression of GK2 mRNA CTD PMID:25449180 NCBI chr14:12,107,071...12,108,923
Ensembl chr14:12,107,020...12,128,473 		JBrowse link
G Gmnc geminin coiled-coil domain containing increases expression ISO Malathion results in increased expression of GMNC mRNA CTD PMID:37047231 NCBI chr11:73,836,255...73,847,698
Ensembl chr11:73,814,533...73,847,328 		JBrowse link
G Gnai1 G protein subunit alpha i1 increases expression ISO Malathion results in increased expression of GNAI1 mRNA CTD PMID:37047231 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression ISO Malathion results in decreased expression of GNAI2 mRNA CTD PMID:32069766 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases activity		 EXP thymoquinone inhibits the reaction [Malathion results in increased activity of GOT1 protein] CTD PMID:33510276 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 increases expression ISO Malathion results in increased expression of GOT1L1 mRNA CTD PMID:37047231 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Gp5 glycoprotein V (platelet) increases expression ISO Malathion results in increased expression of GP5 mRNA CTD PMID:37047231 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Gpr179 G protein-coupled receptor 179 decreases expression ISO Malathion results in decreased expression of GPR179 mRNA CTD PMID:37047231 NCBI chr10:82,324,568...82,340,448
Ensembl chr10:82,337,771...82,340,448 		JBrowse link
G Gps2 G protein pathway suppressor 2 decreases expression ISO Malathion results in decreased expression of GPS2 mRNA CTD PMID:32069766 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions		 EXP Malathion results in increased activity of GPT protein
thymoquinone inhibits the reaction [Malathion results in increased activity of GPT protein]		 CTD PMID:25180440 PMID:33510276 PMID:36370973 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gramd4 GRAM domain containing 4 decreases expression ISO Malathion results in decreased expression of GRAMD4 mRNA CTD PMID:32069766 NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053 		JBrowse link
G Grk1 G protein-coupled receptor kinase 1 increases expression ISO Malathion results in increased expression of GRK1 mRNA CTD PMID:37047231 NCBI chr16:76,122,501...76,135,792
Ensembl chr16:76,123,842...76,135,792 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression EXP Malathion results in increased expression of GSK3B mRNA CTD PMID:25449180 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity		 ISO
EXP		 [Hexachlorocyclohexane co-treated with Malathion] results in decreased activity of GSR protein
zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]		 CTD PMID:16718366 PMID:19429256 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO Malathion results in decreased expression of GSTP1 mRNA CTD PMID:32069766 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gzmb granzyme B decreases expression
multiple interactions		 ISO Malathion results in decreased expression of GZMB protein
Plant Extracts inhibits the reaction [Malathion results in decreased expression of GZMB protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of GZMB protein]		 CTD PMID:32120800 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G H19 H19 imprinted maternally expressed transcript increases expression ISO Malathion results in increased expression of H19 mRNA CTD PMID:37047231 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Has1 hyaluronan synthase 1 increases expression ISO Malathion results in increased expression of HAS1 mRNA CTD PMID:37047231 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Malathion results in increased expression of HBEGF mRNA CTD PMID:37047231 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hdc histidine decarboxylase affects binding ISO Malathion binds to [HDC protein binds to Pyridoxal Phosphate]; Malathion binds to HDC protein CTD PMID:35151785 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO Malathion results in increased expression of HILPDA mRNA CTD PMID:37047231 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Malathion results in increased expression of HMOX1 protein CTD PMID:34778934 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO Malathion results in decreased expression of HNMT mRNA CTD PMID:37047231 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases expression		 ISO [Malathion co-treated with Estrogens] results in increased expression of HRAS mRNA
Malathion results in increased expression of HRAS mRNA; Malathion results in increased expression of HRAS protein		 CTD PMID:18204794 PMID:19787260 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions
decreases expression		 ISO
EXP		 lavender oil inhibits the reaction [Malathion results in decreased expression of HSD17B3 mRNA] CTD PMID:30409133 PMID:36336997 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein increases expression ISO Malathion results in increased expression of HSF2BP mRNA CTD PMID:37047231 NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242 		JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases expression ISO Malathion results in increased expression of HSPB2 protein CTD PMID:19607909 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 decreases expression ISO Malathion results in decreased expression of HTATIP2 mRNA CTD PMID:32069766 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629 		JBrowse link
G Htra4 HtrA serine peptidase 4 decreases expression ISO Malathion results in decreased expression of HTRA4 mRNA CTD PMID:37047231 NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO Malathion results in increased expression of IDO1 mRNA CTD PMID:37047231 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO Malathion results in increased expression of IFI44L mRNA CTD PMID:37047231 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Malathion inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
increases expression		 EXP
ISO		 Malathion results in decreased expression of IFNG protein
Plant Extracts inhibits the reaction [Malathion results in decreased expression of IFNG protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IFNG protein]
Malathion results in increased expression of IFNG mRNA
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]		 CTD PMID:19145326 PMID:24810974 PMID:25180440 PMID:28987951 PMID:32120800 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il11 interleukin 11 increases expression ISO Malathion results in increased expression of IL11 mRNA CTD PMID:37047231 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il13 interleukin 13 increases expression ISO Malathion results in increased expression of IL13 mRNA CTD PMID:37047231 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Malathion results in increased expression of IL13RA2 mRNA CTD PMID:32069766 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Malathion results in increased expression of IL1A mRNA CTD PMID:37047231 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 EXP
ISO		 Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IL1B mRNA] CTD PMID:24810974 PMID:25180440 PMID:28987951 PMID:37047231 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression EXP Malathion results in decreased expression of IL1R2 mRNA CTD PMID:19784758 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression		 ISO Plant Extracts inhibits the reaction [Malathion results in decreased expression of IL2 protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IL2 protein] CTD PMID:32120800 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Malathion results in increased expression of IL23A mRNA CTD PMID:37047231 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il24 interleukin 24 increases expression ISO Malathion results in increased expression of IL24 mRNA CTD PMID:37047231 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO Malathion results in increased expression of IL36G mRNA CTD PMID:37047231 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions		 ISO Malathion results in decreased expression of IL4 protein
Plant Extracts inhibits the reaction [Malathion results in decreased expression of IL4 protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IL4 protein]		 CTD PMID:32120800 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 EXP
ISO		 Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA] CTD PMID:24810974 PMID:25180440 PMID:37047231 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A increases expression
decreases methylation		 ISO Malathion results in increased expression of INHBA mRNA
Malathion results in decreased methylation of INHBA promoter		 CTD PMID:37047231 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Ins1 insulin 1 increases expression EXP Malathion results in increased expression of INS1 protein CTD PMID:25449180 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression ISO Malathion results in increased expression of IRAK1 mRNA CTD PMID:32069766 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Malathion results in increased expression of IRAK2 mRNA CTD PMID:37047231 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irx2 iroquois homeobox 2 increases expression ISO Malathion results in increased expression of IRX2 mRNA CTD PMID:37047231 NCBI chr 1:30,660,960...30,666,378
Ensembl chr 1:30,660,960...30,666,378 		JBrowse link
G Itgb8 integrin subunit beta 8 decreases methylation
increases expression		 ISO Malathion results in decreased methylation of ITGB8 promoter
Malathion results in increased expression of ITGB8 mRNA		 CTD PMID:37047231 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Kazn kazrin, periplakin interacting protein decreases expression ISO Malathion results in decreased expression of KAZN mRNA CTD PMID:37047231 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074 		JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 increases expression ISO Malathion results in increased expression of KCNH5 mRNA CTD PMID:37047231 NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases methylation
decreases expression		 ISO Malathion results in increased methylation of KCNMA1 promoter
Malathion results in decreased expression of KCNMA1 mRNA		 CTD PMID:37047231 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kif6 kinesin family member 6 decreases expression ISO Malathion results in decreased expression of KIF6 mRNA CTD PMID:37047231 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions		 EXP Malathion results in increased expression of KIT protein
Rosmarinic Acid inhibits the reaction [Malathion results in increased expression of KIT protein]; thymoquinone inhibits the reaction [Malathion results in increased expression of KIT protein]		 CTD PMID:33510276 PMID:34262720 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kmt2a lysine methyltransferase 2A increases mutagenesis
increases expression		 ISO Malathion results in increased mutagenesis of KMT2A gene
Malathion results in increased expression of KMT2A mRNA mutant form		 CTD PMID:28624474 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Krt14 keratin 14 increases expression ISO Malathion results in increased expression of KRT14 mRNA CTD PMID:37047231 NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt17 keratin 17 increases expression ISO Malathion results in increased expression of KRT17 mRNA CTD PMID:37047231 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392 		JBrowse link
G Krtap27-1 keratin associated protein 27-1 increases expression ISO Malathion results in increased expression of KRTAP27-1 mRNA CTD PMID:37047231 NCBI chr11:27,980,875...27,982,002 JBrowse link
G L1td1 LINE-1 type transposase domain containing 1 affects expression
multiple interactions
increases methylation		 EXP Malathion affects the expression of L1TD1 mRNA
[Malathion results in increased methylation of L1TD1 promoter] which affects the expression of L1TD1 mRNA		 CTD PMID:36370973 NCBI chr 5:113,373,193...113,386,088
Ensembl chr 5:113,379,870...113,385,730 		JBrowse link
G Lat linker for activation of T cells increases expression EXP Malathion results in increased expression of LAT mRNA CTD PMID:19784758 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Lcorl ligand dependent nuclear receptor corepressor-like increases expression ISO Malathion results in increased expression of LCORL mRNA CTD PMID:37047231 NCBI chr14:65,271,339...65,407,732
Ensembl chr14:65,271,135...65,404,174 		JBrowse link
G Lemd1 LEM domain containing 1 increases expression ISO Malathion results in increased expression of LEMD1 mRNA CTD PMID:37047231 NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948 		JBrowse link
G Lgals1 galectin 1 decreases expression ISO Malathion results in decreased expression of LGALS1 mRNA CTD PMID:32069766 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Malathion results in increased expression of LIF mRNA CTD PMID:37047231 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lin28b lin-28 homolog B increases expression ISO Malathion results in increased expression of LIN28B mRNA CTD PMID:37047231 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077 		JBrowse link
G Lingo1 leucine rich repeat and Ig domain containing 1 decreases expression ISO Malathion results in decreased expression of LINGO1 mRNA CTD PMID:37047231 NCBI chr 8:57,011,272...57,193,496
Ensembl chr 8:57,010,007...57,196,544 		JBrowse link
G Lmbr1 limb development membrane protein 1 increases expression ISO Malathion results in increased expression of LMBR1 mRNA CTD PMID:37047231 NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368 		JBrowse link
G LOC120095955 mucin-12-like decreases expression ISO Malathion results in decreased expression of MUC12 mRNA CTD PMID:37047231 NCBI chr12:19,486,041...19,493,995 JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 increases expression ISO Malathion results in increased expression of LPCAT4 mRNA CTD PMID:32069766 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875 		JBrowse link
G Lrguk leucine-rich repeats and guanylate kinase domain containing decreases expression ISO Malathion results in decreased expression of LRGUK mRNA CTD PMID:37047231 NCBI chr 4:62,647,222...62,770,268
Ensembl chr 4:62,647,264...62,770,319 		JBrowse link
G Lrp3 LDL receptor related protein 3 decreases expression ISO Malathion results in decreased expression of LRP3 mRNA CTD PMID:37047231 NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110 		JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 decreases expression ISO Malathion results in decreased expression of LYPD1 mRNA CTD PMID:37047231 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493 		JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 increases expression ISO Malathion results in increased expression of LZTS1 mRNA CTD PMID:37047231 NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203 		JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 decreases expression ISO Malathion results in decreased expression of LZTS2 mRNA CTD PMID:32069766 NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423 		JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 decreases expression ISO Malathion results in decreased expression of MACROD2 mRNA CTD PMID:37047231 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases expression ISO Malathion results in decreased expression of MAP2K3 mRNA CTD PMID:32069766 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 increases expression ISO Malathion results in increased expression of MARCHF3 mRNA CTD PMID:37047231 NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150 		JBrowse link
G Mbp myelin basic protein decreases expression ISO Malathion results in decreased expression of MBP mRNA CTD PMID:37047231 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions
increases expression		 ISO [Malathion co-treated with Estrogens] results in increased expression of MCM2 mRNA
Malathion results in increased expression of MCM2 mRNA		 CTD PMID:18204794 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Meis1 Meis homeobox 1 decreases expression ISO Malathion results in decreased expression of MEIS1 mRNA CTD PMID:37047231 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Malathion results in increased expression of MET mRNA CTD PMID:37047231 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid increases expression ISO Malathion results in increased expression of MFSD2A mRNA CTD PMID:37047231 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Mill1 MHC I like leukocyte 1 increases expression ISO Malathion results in increased expression of MICA mRNA CTD PMID:32069766 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Malathion results in increased expression of MMP1 mRNA CTD PMID:37047231 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Malathion results in increased expression of MMP10 mRNA CTD PMID:37047231 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Malathion results in increased expression of MMP12 mRNA CTD PMID:37047231 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Malathion results in increased expression of MMP3 mRNA CTD PMID:37047231 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity		 EXP Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein] CTD PMID:24810974 PMID:25180440 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Malathion results in decreased expression of COX1 mRNA CTD PMID:18214912 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Malathion results in decreased expression of COX3 mRNA CTD PMID:18214912 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 increases expression ISO Malathion results in increased expression of MT1E mRNA CTD PMID:37047231 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO Malathion results in increased expression of MT2A mRNA CTD PMID:37047231 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mybphl myosin binding protein H-like increases expression ISO Malathion results in increased expression of MYBPHL mRNA CTD PMID:37047231 NCBI chr 2:196,005,297...196,018,826
Ensembl chr 2:196,005,325...196,018,824 		JBrowse link
G Myo1b myosin Ib increases expression ISO Malathion results in increased expression of MYO1B mRNA CTD PMID:37047231 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Myzap myocardial zonula adherens protein increases expression ISO Malathion results in increased expression of MYZAP mRNA CTD PMID:37047231 NCBI chr 8:72,155,817...72,243,036
Ensembl chr 8:72,131,530...72,243,036 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 decreases expression ISO Malathion results in decreased expression of NDUFS7 mRNA CTD PMID:37047231 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195 		JBrowse link
G Nefh neurofilament heavy chain affects expression
increases expression		 EXP Malathion affects the expression of NEFH mRNA
Malathion results in increased expression of NEFH mRNA		 CTD PMID:22954530 PMID:28385489 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nek10 NIMA-related kinase 10 decreases expression ISO Malathion results in decreased expression of NEK10 mRNA CTD PMID:37047231 NCBI chr15:10,387,063...10,564,177
Ensembl chr15:10,381,140...10,559,722 		JBrowse link
G Neu4 neuraminidase 4 increases expression ISO Malathion results in increased expression of NEU4 mRNA CTD PMID:37047231 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576 		JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 increases expression ISO Malathion results in increased expression of NEURL3 mRNA CTD PMID:37047231 NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO Malathion results in increased activity of NFE2L2 protein CTD PMID:30114225 PMID:30203046 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfib nuclear factor I/B decreases expression ISO Malathion results in decreased expression of NFIB mRNA CTD PMID:37047231 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ninj1 ninjurin 1 decreases expression ISO Malathion results in decreased expression of NINJ1 mRNA CTD PMID:32069766 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression ISO Malathion results in decreased expression of NNT mRNA CTD PMID:37047231 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Malathion results in increased expression of NOS2 mRNA CTD PMID:20233601 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Malathion results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
increases activity		 ISO Malathion results in increased expression of NR1I3 mRNA
Malathion results in increased activity of NR1I3 protein		 CTD PMID:22310298 PMID:28927721 PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Malathion results in increased expression of NR4A1 mRNA CTD PMID:37047231 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases methylation
increases expression		 ISO Malathion results in decreased methylation of NR4A3 promoter
Malathion results in increased expression of NR4A3 mRNA		 CTD PMID:37047231 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Ntn1 netrin 1 increases expression ISO Malathion results in increased expression of NTN1 mRNA CTD PMID:37047231 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Malathion results in increased expression of NTRK2 mRNA CTD PMID:32069766 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ocln occludin multiple interactions
decreases expression		 EXP [Malathion co-treated with Lead] results in decreased expression of OCLN protein
Malathion results in decreased expression of OCLN protein		 CTD PMID:20970449 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein increases expression ISO Malathion results in increased expression of OCSTAMP mRNA CTD PMID:37047231 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991 		JBrowse link
G Odam odontogenic, ameloblast associated decreases expression ISO Malathion results in decreased expression of ODAM mRNA CTD PMID:37047231 NCBI chr14:20,193,286...20,202,517
Ensembl chr14:20,193,302...20,202,517 		JBrowse link
G Odf2l outer dense fiber of sperm tails 2-like decreases expression ISO Malathion results in decreased expression of ODF2L mRNA CTD PMID:37047231 NCBI chr 2:234,036,049...234,072,751
Ensembl chr 2:234,033,652...234,072,747 		JBrowse link
G Olr1433 olfactory receptor 1433 increases expression ISO Malathion results in increased expression of OR2W3 mRNA CTD PMID:37047231 NCBI chr10:43,042,427...43,046,293
Ensembl chr10:43,037,857...43,046,701 		JBrowse link
G Olr1523 olfactory receptor 1523 decreases expression ISO Malathion results in decreased expression of OR4D1 mRNA CTD PMID:37047231 NCBI chr10:72,708,272...72,709,213
Ensembl chr10:72,707,063...72,715,311 		JBrowse link
G Olr35 olfactory receptor 35 decreases expression ISO Malathion results in decreased expression of OR2AT4 mRNA CTD PMID:37047231 NCBI chr 1:153,994,678...154,043,281
Ensembl chr 1:154,041,306...154,043,257 		JBrowse link
G Omg oligodendrocyte-myelin glycoprotein affects expression ISO Malathion affects the expression of OMG mRNA CTD PMID:37047231 NCBI chr10:64,461,350...64,464,084
Ensembl chr10:64,461,350...64,464,084 		JBrowse link
G Opn5 opsin 5 decreases expression ISO Malathion results in decreased expression of OPN5 mRNA CTD PMID:37047231 NCBI chr 9:18,368,393...18,416,098
Ensembl chr 9:18,368,416...18,415,476 		JBrowse link
G Or4f7b olfactory receptor family 4 subfamily F member 7B decreases expression ISO Malathion results in decreased expression of OR4F29 mRNA CTD PMID:37047231 NCBI chr 3:98,388,815...98,394,276
Ensembl chr 3:98,387,865...98,395,686 		JBrowse link
G Or4f7c olfactory receptor family 4 subfamily F member 7C decreases expression ISO Malathion results in decreased expression of OR4F21 mRNA CTD PMID:37047231 NCBI chr 3:98,458,889...98,459,827
Ensembl chr 3:98,457,871...98,464,794 		JBrowse link
G Or6c2 olfactory receptor family 6 subfamily C member 2 decreases expression ISO Malathion results in decreased expression of OR6C2 mRNA CTD PMID:37047231 NCBI chr 7:2,188,601...2,189,539 JBrowse link
G Or9g4 olfactory receptor family 9 subfamily G member 4 decreases expression ISO Malathion results in decreased expression of OR9G4 mRNA CTD PMID:37047231 NCBI chr 3:70,727,963...70,728,901
Ensembl chr 3:70,726,935...70,732,439 		JBrowse link
G P2rx1 purinergic receptor P2X 1 increases expression EXP Malathion results in increased expression of P2RX1 mRNA CTD PMID:19784758 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G Palmd palmdelphin decreases expression ISO Malathion results in decreased expression of PALMD mRNA CTD PMID:37047231 NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO Malathion results in increased cleavage of PARP1 protein
Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein]		 CTD PMID:29027213 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pax1 paired box 1 increases expression ISO Malathion results in increased expression of PAX1 mRNA CTD PMID:32069766 NCBI chr 3:134,792,330...134,801,637
Ensembl chr 3:134,789,182...134,801,636 		JBrowse link
G Pcdh15 protocadherin related 15 decreases expression ISO Malathion results in decreased expression of PCDH15 mRNA CTD PMID:37047231 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719 		JBrowse link
G Pcdhb19 protocadherin beta 19 decreases expression ISO Malathion results in decreased expression of PCDHB12 mRNA CTD PMID:37047231 NCBI chr18:29,204,838...29,207,646 JBrowse link
G Pcdhgb1 protocadherin gamma subfamily B, 1 increases expression ISO Malathion results in increased expression of PCDHGB1 mRNA CTD PMID:37047231 NCBI chr18:29,501,739...29,508,024 JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA] CTD PMID:25449180 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression		 ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pde6c phosphodiesterase 6C decreases expression ISO Malathion results in decreased expression of PDE6C mRNA CTD PMID:37047231 NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 decreases expression ISO Malathion results in decreased expression of PDIA2 mRNA CTD PMID:37047231 NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Malathion results in decreased expression of PEBP1 mRNA CTD PMID:32069766 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
G Peg10 paternally expressed 10 increases expression ISO Malathion results in increased expression of PEG10 mRNA CTD PMID:37047231 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621 		JBrowse link
G Pfn1 profilin 1 decreases expression ISO Malathion results in decreased expression of PFN1 mRNA CTD PMID:32069766 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Phb1 prohibitin 1 decreases expression ISO Malathion results in decreased expression of PHB1 mRNA CTD PMID:32069766 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pitx1 paired-like homeodomain 1 decreases expression ISO Malathion results in decreased expression of PITX1 mRNA CTD PMID:37047231 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291 		JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Malathion results in decreased expression of PLAT mRNA CTD PMID:16079077 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Malathion results in increased expression of PLAU mRNA CTD PMID:32069766 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO Malathion results in increased expression of PLAUR mRNA CTD PMID:37047231 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcb4 phospholipase C, beta 4 increases expression ISO Malathion results in increased expression of PLCB4 mRNA CTD PMID:37047231 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392 		JBrowse link
G Plekhd1 pleckstrin homology and coiled-coil domain containing D1 decreases expression ISO Malathion results in decreased expression of PLEKHD1 mRNA CTD PMID:37047231 NCBI chr 6:100,340,655...100,371,942
Ensembl chr 6:100,340,655...100,371,941 		JBrowse link
G Plin1 perilipin 1 increases expression ISO Malathion results in increased expression of PLIN1 mRNA CTD PMID:37047231 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Plin2 perilipin 2 increases expression ISO Malathion results in increased expression of PLIN2 mRNA CTD PMID:37047231 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO Malathion results in decreased expression of PLP1 mRNA CTD PMID:37047231 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Pls3 plastin 3 increases expression ISO Malathion results in increased expression of PLS3 mRNA CTD PMID:37047231 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Plvap plasmalemma vesicle associated protein decreases expression ISO Malathion results in decreased expression of PLVAP mRNA CTD PMID:37047231 NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301 		JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Malathion results in decreased expression of PML mRNA CTD PMID:32069766 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Malathion results in decreased expression of PPARA mRNA CTD PMID:25689681 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkd1 protein kinase D1 increases expression ISO Malathion results in increased expression of PRKD1 mRNA CTD PMID:32069766 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prox2 prospero homeobox 2 decreases expression ISO Malathion results in decreased expression of PROX2 mRNA CTD PMID:37047231 NCBI chr 6:104,731,385...104,758,619
Ensembl chr 6:104,733,002...104,742,093 		JBrowse link
G Proz protein Z, vitamin K-dependent plasma glycoprotein decreases expression ISO Malathion results in decreased expression of PROZ mRNA CTD PMID:37047231 NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480 		JBrowse link
G Ptcra pre T-cell antigen receptor alpha decreases expression ISO Malathion results in decreased expression of PTCRA mRNA CTD PMID:37047231 NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:14,218,802...14,229,235 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Malathion results in increased expression of PTGS2 mRNA; Malathion results in increased expression of PTGS2 protein CTD PMID:30673264 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pygl glycogen phosphorylase L multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA] CTD PMID:25449180 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310 		JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 increases expression ISO Malathion results in increased expression of RAB11FIP3 mRNA CTD PMID:32069766 NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Rab3c RAB3C, member RAS oncogene family decreases expression ISO Malathion results in decreased expression of RAB3C mRNA CTD PMID:37047231 NCBI chr 2:41,627,720...41,843,541
Ensembl chr 2:41,627,720...41,843,749 		JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 increases expression ISO Malathion results in increased expression of RAPGEF5 mRNA CTD PMID:37047231 NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936 		JBrowse link
G Rbp3 retinol binding protein 3 decreases expression ISO Malathion results in decreased expression of RBP3 mRNA CTD PMID:37047231 NCBI chr16:9,267,538...9,276,006
Ensembl chr16:9,267,538...9,276,006 		JBrowse link
G Rbp7 retinol binding protein 7 decreases expression ISO Malathion results in decreased expression of RBP7 mRNA CTD PMID:37047231 NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339 		JBrowse link
G Redic1 regulator of DNA class I crossover intermediates 1 decreases expression ISO Malathion results in decreased expression of REDIC1 mRNA CTD PMID:37047231 NCBI chr 7:122,318,495...122,386,002
Ensembl chr 7:122,318,499...122,385,983 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions		 EXP
ISO		 Malathion results in increased expression of RELA mRNA
Taurine inhibits the reaction [Malathion results in increased expression of RELA mRNA]		 CTD PMID:28987951 PMID:30673264 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reln reelin increases expression ISO Malathion results in increased expression of RELN mRNA CTD PMID:37047231 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rfc3 replication factor C subunit 3 decreases expression ISO Malathion results in decreased expression of RFC3 mRNA CTD PMID:16079077 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778 		JBrowse link
G Rft1 RFT1 homolog decreases expression ISO Malathion results in decreased expression of RFT1 mRNA CTD PMID:37047231 NCBI chr16:5,827,063...5,861,120
Ensembl chr16:5,827,088...5,861,120 		JBrowse link
G Rhoa ras homolog family member A decreases activity ISO Malathion results in decreased activity of RHOA protein CTD PMID:37270087 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhox13 Rhox homeobox family member 13 increases expression ISO Malathion results in increased expression of RHOXF1 mRNA CTD PMID:37047231 NCBI chr  X:116,911,226...116,917,758
Ensembl chr  X:116,911,329...116,917,644 		JBrowse link
G Rimbp2 RIMS binding protein 2 decreases expression ISO Malathion results in decreased expression of RIMBP2 mRNA CTD PMID:37047231 NCBI chr12:27,747,615...27,946,256
Ensembl chr12:27,747,980...27,956,763 		JBrowse link
G Rnase6 ribonuclease A family member 6 increases expression EXP Malathion results in increased expression of RNASE6 mRNA CTD PMID:19784758 NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328 		JBrowse link
G Rnf170 ring finger protein 170 increases expression ISO Malathion results in increased expression of RNF170 mRNA CTD PMID:37047231 NCBI chr16:65,928,886...65,954,092
Ensembl chr16:65,928,895...65,954,083 		JBrowse link
G Rnf183 ring finger protein 183 increases expression ISO Malathion results in increased expression of RNF183 mRNA CTD PMID:37047231 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191 		JBrowse link
G Robo4 roundabout guidance receptor 4 decreases expression ISO Malathion results in decreased expression of ROBO4 mRNA CTD PMID:37047231 NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519 		JBrowse link
G Rph3a rabphilin 3A decreases expression ISO Malathion results in decreased expression of RPH3A mRNA CTD PMID:37047231 NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Malathion results in increased expression of RRAD mRNA CTD PMID:37047231 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G Rs1 retinoschisin 1 increases expression ISO Malathion results in increased expression of RS1 mRNA CTD PMID:37047231 NCBI chr  X:33,962,440...33,992,203
Ensembl chr  X:33,963,657...33,992,115 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO Malathion results in increased expression of RSAD2 mRNA CTD PMID:37047231 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rspo2 R-spondin 2 decreases expression ISO Malathion results in decreased expression of RSPO2 mRNA CTD PMID:37047231 NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 decreases expression ISO Malathion results in decreased expression of HLA-E mRNA CTD PMID:32069766 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 decreases expression ISO Malathion results in decreased expression of HLA-A mRNA CTD PMID:32069766 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression ISO Malathion results in increased expression of RUNX1 mRNA mutant form CTD PMID:28624474 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G S100a1 S100 calcium binding protein A1 decreases expression ISO Malathion results in decreased expression of S100A1 mRNA CTD PMID:37047231 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544 		JBrowse link
G Scg5 secretogranin V increases expression ISO Malathion results in increased expression of SCG5 mRNA CTD PMID:37047231 NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463 		JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 decreases expression ISO Malathion results in decreased expression of SCN9A mRNA CTD PMID:37047231 NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Malathion results in increased expression of SERPINB2 mRNA CTD PMID:37047231 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Sftpb surfactant protein B decreases expression
multiple interactions		 ISO
EXP		 Malathion results in decreased expression of SFTPB mRNA
Malathion results in decreased expression of SFTPB mRNA; Malathion results in decreased expression of SFTPB protein
Rosmarinic Acid inhibits the reaction [Malathion results in decreased expression of SFTPB protein]; thymoquinone inhibits the reaction [Malathion results in decreased expression of SFTPB mRNA]		 CTD PMID:33510276 PMID:34262720 PMID:37047231 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 increases expression ISO Malathion results in increased expression of SGPP2 mRNA CTD PMID:37047231 NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457 		JBrowse link
G Shc1 SHC adaptor protein 1 increases expression ISO Malathion results in increased expression of SHC1 mRNA CTD PMID:32069766 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Shisa3 shisa family member 3 increases expression ISO Malathion results in increased expression of SHISA3 mRNA CTD PMID:37047231 NCBI chr14:40,563,672...40,568,244
Ensembl chr14:40,563,673...40,568,244 		JBrowse link
G Shisa9 shisa family member 9 increases expression ISO Malathion results in increased expression of SHISA9 mRNA CTD PMID:37047231 NCBI chr10:3,335,616...3,629,334
Ensembl chr10:3,337,979...3,627,773 		JBrowse link
G Shtn1 shootin 1 decreases expression ISO Malathion results in decreased expression of SHTN1 mRNA CTD PMID:37047231 NCBI chr 1:258,121,966...258,225,861
Ensembl chr 1:258,121,968...258,228,265 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO Malathion results in decreased expression of SLC14A1 mRNA CTD PMID:37047231 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Malathion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc4a5 solute carrier family 4 member 5 decreases expression ISO Malathion results in decreased expression of SLC4A5 mRNA CTD PMID:37047231 NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323 		JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression ISO Malathion results in increased expression of SLCO4A1 mRNA CTD PMID:37047231 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305 		JBrowse link
G Smim32 small integral membrane protein 32 decreases expression ISO Malathion results in decreased expression of SMIM32 mRNA CTD PMID:37047231 NCBI chr17:7,853,492...7,857,235 JBrowse link
G Snca synuclein alpha increases expression
multiple interactions		 EXP Malathion results in increased expression of SNCA mRNA; Malathion results in increased expression of SNCA protein
crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; crocin inhibits the reaction [Malathion results in increased expression of SNCA protein]; Levodopa inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; Levodopa inhibits the reaction [Malathion results in increased expression of SNCA protein]		 CTD PMID:35274200 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sntg1 syntrophin, gamma 1 decreases expression ISO Malathion results in decreased expression of SNTG1 mRNA CTD PMID:37047231 NCBI chr 5:9,980,550...10,794,666
Ensembl chr 5:9,981,115...10,791,181 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO Malathion results in decreased expression of SOCS3 mRNA CTD PMID:32069766 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sod1 superoxide dismutase 1 increases activity
decreases expression
multiple interactions		 EXP
ISO		 Malathion results in increased activity of SOD1 protein
Malathion results in decreased expression of SOD1 protein
lavender oil inhibits the reaction [Malathion results in decreased expression of SOD1 protein]
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein]		 CTD PMID:20194575 PMID:30409133 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression		 EXP
ISO		 alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; Malathion results in increased expression of and results in increased activity of SOD2 protein
lavender oil inhibits the reaction [Malathion results in decreased expression of SOD2 protein]		 CTD PMID:20194575 PMID:30409133 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spata17 spermatogenesis associated 17 decreases expression ISO Malathion results in decreased expression of SPATA17 mRNA CTD PMID:37047231 NCBI chr13:98,605,986...98,784,855
Ensembl chr13:98,605,986...98,784,929 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A increases expression ISO Malathion results in increased expression of SPDYA mRNA CTD PMID:37047231 NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850 		JBrowse link
G Spink13 serine peptidase inhibitor Kazal type 13 decreases expression ISO Malathion results in decreased expression of SPINK13 mRNA CTD PMID:37047231 NCBI chr18:56,064,839...56,206,257
Ensembl chr18:56,064,839...56,206,257 		JBrowse link
G Spink4 serine peptidase inhibitor, Kazal type 4 decreases expression ISO Malathion results in decreased expression of SPINK4 mRNA CTD PMID:37047231 NCBI chr 5:56,043,936...56,064,841
Ensembl chr 5:55,981,624...56,064,795 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression EXP Malathion results in decreased expression of SRSF5 mRNA CTD PMID:19784758 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Sspo SCO-spondin decreases expression ISO Malathion results in decreased expression of SSPOP mRNA CTD PMID:37047231 NCBI chr 4:77,394,915...77,450,526
Ensembl chr 4:77,397,059...77,450,412 		JBrowse link
G Sst somatostatin decreases expression ISO Malathion results in decreased expression of SST mRNA CTD PMID:37047231 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Sstr2 somatostatin receptor 2 increases expression ISO Malathion results in increased expression of SSTR2 mRNA CTD PMID:37047231 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351 		JBrowse link
G St6gal2 ST6 beta-galactoside alpha-2,6-sialyltransferase 2 increases expression ISO Malathion results in increased expression of ST6GAL2 mRNA CTD PMID:37047231 NCBI chr 9:9,181,744...9,274,161
Ensembl chr 9:9,182,399...9,269,697 		JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 increases expression EXP Malathion results in increased expression of ST8SIA1 mRNA CTD PMID:19784758 NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 increases expression ISO Malathion results in increased expression of ST8SIA4 mRNA CTD PMID:37047231 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions		 ISO Malathion results in decreased expression of STAR mRNA
lavender oil inhibits the reaction [Malathion results in decreased expression of STAR mRNA]		 CTD PMID:30409133 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation EXP Malathion results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Malathion results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stk36 serine/threonine kinase 36 decreases expression ISO Malathion results in decreased expression of STK36 mRNA CTD PMID:37047231 NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422 		JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 decreases expression ISO Malathion results in decreased expression of STRA6 mRNA CTD PMID:37047231 NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860 		JBrowse link
G Tcf7l1 transcription factor 7 like 1 increases expression ISO Malathion results in increased expression of TCF7L1 mRNA CTD PMID:37047231 NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287 		JBrowse link
G Tchhl1 trichohyalin-like 1 decreases expression ISO Malathion results in decreased expression of TCHHL1 mRNA CTD PMID:37047231 NCBI chr 2:179,134,941...179,138,467
Ensembl chr 2:179,135,796...179,138,202 		JBrowse link
G Tdrd1 tudor domain containing 1 increases expression ISO Malathion results in increased expression of TDRD1 mRNA CTD PMID:37047231 NCBI chr 1:255,871,939...255,919,222
Ensembl chr 1:255,875,887...255,915,871 		JBrowse link
G Tdrd6 tudor domain containing 6 increases expression ISO Malathion results in increased expression of TDRD6 mRNA CTD PMID:37047231 NCBI chr 9:17,344,033...17,359,348
Ensembl chr 9:17,344,026...17,359,344 		JBrowse link
G Tdrp testis development related protein decreases expression ISO Malathion results in decreased expression of TDRP mRNA CTD PMID:37047231 NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420 		JBrowse link
G Tek TEK receptor tyrosine kinase increases expression ISO Malathion results in increased expression of TEK mRNA CTD PMID:32069766 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 affects expression EXP Malathion affects the expression of TET1 mRNA CTD PMID:36370973 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 decreases expression EXP Malathion results in decreased expression of TET2 mRNA CTD PMID:36370973 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
G Tet3 tet methylcytosine dioxygenase 3 affects expression EXP Malathion affects the expression of TET3 mRNA CTD PMID:36370973 NCBI chr 4:115,867,412...115,964,433
Ensembl chr 4:115,871,265...115,964,193 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Malathion results in increased expression of TFPI2 mRNA CTD PMID:37047231 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Tfrc transferrin receptor increases expression ISO Malathion results in increased expression of TFRC mRNA CTD PMID:32069766 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tg thyroglobulin decreases expression EXP Malathion results in decreased expression of TG mRNA; Malathion results in decreased expression of TG protein CTD PMID:29143548 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tifab TIFA inhibitor decreases expression ISO Malathion results in decreased expression of TIFAB mRNA CTD PMID:37047231 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression EXP Malathion results in decreased expression of TIMP3 mRNA CTD PMID:19784758 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression		 EXP [Malathion co-treated with Lead] results in decreased expression of TJP1 protein
Malathion results in decreased expression of TJP1 protein		 CTD PMID:20970449 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 multiple interactions
decreases expression		 EXP [Malathion co-treated with Lead] results in decreased expression of TJP2 protein
Malathion results in decreased expression of TJP2 protein		 CTD PMID:20970449 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression		 ISO Plant Extracts inhibits the reaction [Malathion results in increased expression of TLR4 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of TLR4 protein] CTD PMID:32120800 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr8 toll-like receptor 8 increases expression ISO Malathion results in increased expression of TLR8 mRNA CTD PMID:32069766 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tmem114 transmembrane protein 114 decreases expression ISO Malathion results in decreased expression of TMEM114 mRNA CTD PMID:37047231 NCBI chr10:7,168,998...7,185,251
Ensembl chr10:7,169,746...7,185,251 		JBrowse link
G Tmem158 transmembrane protein 158 increases expression ISO Malathion results in increased expression of TMEM158 mRNA CTD PMID:37047231 NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673 		JBrowse link
G Tmem241 transmembrane protein 241 decreases expression ISO Malathion results in decreased expression of TMEM241 mRNA CTD PMID:37047231 NCBI chr18:3,168,072...3,318,340
Ensembl chr18:3,168,067...3,318,293 		JBrowse link
G Tmem65 transmembrane protein 65 increases expression ISO Malathion results in increased expression of TMEM65 mRNA CTD PMID:37047231 NCBI chr 7:90,336,997...90,378,930
Ensembl chr 7:90,274,142...90,379,474 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP
ISO		 Malathion results in increased expression of TNF mRNA
Taurine inhibits the reaction [Malathion results in increased expression of TNF mRNA]		 CTD PMID:28987951 PMID:37047231 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Malathion results in increased expression of TNFAIP6 mRNA CTD PMID:37047231 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfaip8l3 TNF alpha induced protein 8 like 3 decreases expression ISO Malathion results in decreased expression of TNFAIP8L3 mRNA CTD PMID:37047231 NCBI chr 8:54,413,503...54,455,512
Ensembl chr 8:54,414,457...54,500,079 		JBrowse link
G Tnfsf15 TNF superfamily member 15 affects expression ISO Malathion affects the expression of TNFSF15 mRNA CTD PMID:37047231 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 increases expression ISO Malathion results in increased expression of TNIP3 mRNA CTD PMID:37047231 NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO
EXP		 Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]
Plant Extracts inhibits the reaction [Malathion results in increased expression of TRP53 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of TRP53 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]
Malathion results in increased expression of TP53 mRNA; Malathion results in increased expression of TP53 protein		 CTD PMID:12505448 PMID:12762645 PMID:18204794 PMID:19787260 PMID:21628957 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression
multiple interactions		 ISO Malathion results in increased expression of TP53I3 mRNA
[Malathion co-treated with Estrogens] results in increased expression of TP53I3 mRNA		 CTD PMID:18204794 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tpd52l3 TPD52 like 3 decreases expression ISO Malathion results in decreased expression of TPD52L3 mRNA CTD PMID:37047231 NCBI chr 1:227,781,173...227,785,040
Ensembl chr 1:227,773,724...227,784,467 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein increases expression ISO Malathion results in increased expression of TPR mRNA CTD PMID:32069766 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Tram1l1 translocation associated membrane protein 1-like 1 increases expression ISO Malathion results in increased expression of TRAM1L1 mRNA CTD PMID:37047231 NCBI chr 2:212,511,130...212,513,311 JBrowse link
G Trim35 tripartite motif-containing 35 decreases expression ISO Malathion results in decreased expression of TRIM35 mRNA CTD PMID:32069766 NCBI chr15:40,493,697...40,510,246
Ensembl chr15:40,493,755...40,510,240 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 increases expression EXP Malathion results in increased expression of TRPC1 mRNA; Malathion results in increased expression of TRPC1 protein CTD PMID:22674931 NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 increases expression
decreases expression		 EXP
ISO		 Malathion results in increased expression of TRPC4 mRNA; Malathion results in increased expression of TRPC4 protein
Malathion results in decreased expression of TRPC4 mRNA		 CTD PMID:22674931 PMID:37047231 NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768 		JBrowse link
G Trpc5os TRPC5 opposite strand increases expression ISO Malathion results in increased expression of TRPC5OS mRNA CTD PMID:37047231 NCBI chr  X:108,025,172...108,044,201
Ensembl chr  X:108,024,924...108,046,581 		JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Malathion results in decreased expression of TSHR protein CTD PMID:29143548 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
G Ttc9 tetratricopeptide repeat domain 9 decreases expression ISO Malathion results in decreased expression of TTC9 mRNA CTD PMID:37047231 NCBI chr 6:101,333,274...101,368,110
Ensembl chr 6:101,333,141...101,368,110 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator decreases expression ISO Malathion results in decreased expression of TUSC2 mRNA CTD PMID:32069766 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO Malathion results in increased expression of TWIST1 mRNA CTD PMID:32069766 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Txnrd3 thioredoxin reductase 3 decreases expression ISO Malathion results in decreased expression of TXNRD3 mRNA CTD PMID:37047231 NCBI chr 4:122,072,548...122,112,493
Ensembl chr 4:122,072,548...122,112,491 		JBrowse link
G Tyms thymidylate synthetase decreases expression ISO Malathion results in decreased expression of TYMS mRNA CTD PMID:16079077 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ubd ubiquitin D increases expression ISO Malathion results in increased expression of UBD mRNA CTD PMID:37047231 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Umodl1 uromodulin-like 1 increases expression ISO Malathion results in increased expression of UMODL1 mRNA CTD PMID:37047231 NCBI chr20:9,027,751...9,087,133
Ensembl chr20:9,025,724...9,087,146 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression ISO Malathion results in increased expression of USP2 mRNA CTD PMID:37047231 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked increases expression ISO Malathion results in increased expression of USP27X mRNA CTD PMID:37047231 NCBI chr  X:15,123,620...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor decreases expression ISO Malathion results in decreased expression of VHL mRNA CTD PMID:32069766 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Vpreb3 V-set pre-B cell surrogate light chain 3 increases expression ISO Malathion results in increased expression of VPREB3 mRNA CTD PMID:32069766 NCBI chr20:12,717,421...12,718,785
Ensembl chr20:12,716,779...12,719,520 		JBrowse link
G Wbp2nl WBP2 N-terminal like decreases expression ISO Malathion results in decreased expression of WBP2NL mRNA CTD PMID:37047231 NCBI chr 7:113,814,793...113,831,974
Ensembl chr 7:113,814,992...113,831,333 		JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A decreases expression ISO Malathion results in decreased expression of WFDC6 mRNA CTD PMID:37047231 NCBI chr 3:153,305,336...153,309,144
Ensembl chr 3:153,305,336...153,309,144 		JBrowse link
G Wipf3 WAS/WASL interacting protein family, member 3 decreases expression ISO Malathion results in decreased expression of WIPF3 mRNA CTD PMID:37047231 NCBI chr 4:83,550,075...83,629,929
Ensembl chr 4:83,550,468...83,629,386 		JBrowse link
G Wt1 WT1 transcription factor increases expression ISO Malathion results in increased expression of WT1 mRNA CTD PMID:32069766 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xkr4 XK related 4 decreases expression ISO Malathion results in decreased expression of XKR4 mRNA CTD PMID:37047231 NCBI chr 5:15,896,818...16,297,733
Ensembl chr 5:15,895,863...16,282,962 		JBrowse link
G Zfp42 zinc finger protein 42 decreases expression ISO Malathion results in decreased expression of ZFP42 mRNA CTD PMID:37047231 NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 increases expression ISO Malathion results in increased expression of ZFPM2 mRNA CTD PMID:37047231 NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:71,678,880...72,116,205 		JBrowse link
G Zscan5b zinc finger and SCAN domain containing 5B decreases expression ISO Malathion results in decreased expression of ZSCAN5B mRNA CTD PMID:37047231 NCBI chr 1:67,666,684...67,674,238
Ensembl chr 1:67,666,691...67,674,238 		JBrowse link
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