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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:L-ornithine
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Accession:CHEBI:15729 term browser browse the term
Definition:An optically active form of ornithine having L-configuration.
Synonyms:related_synonym: (2S)-2,5-diaminopentanoic acid;   (S)-2,5-Diaminopentanoate;   (S)-2,5-Diaminopentanoic acid;   (S)-2,5-diaminovaleric acid;   (S)-alpha,delta-diaminovaleric acid;   (S)-ornithine;   Formula=C5H12N2O2;   InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1;   InChIKey=AHLPHDHHMVZTML-BYPYZUCNSA-N;   SMILES=NCCC[C@H](N)C(O)=O
 alt_id: CHEBI:13148;   CHEBI:21367;   CHEBI:6280
 xref: CAS:70-26-8;   DrugBank:DB00129;   Drug_Central:3401;   Gmelin:327282;   HMDB:HMDB0000214;   KEGG:C00077;   KEGG:D08302;   KNApSAcK:C00001384;   MetaCyc:ORNITHINE;   PDBeChem:ORN;   PMID:15576628;   PMID:17190852;   PMID:18676473;   PMID:19083482;   PMID:19173225;   PMID:22033378;   PMID:22133808;   PMID:22387109;   PMID:22735334;   Reaxys:1722298;   Wikipedia:Ornithine
 cyclic_relationship: is_conjugate_acid_of CHEBI:46914;   is_conjugate_base_of CHEBI:46911;   is_enantiomer_of CHEBI:16176


show annotations for term's descendants           Sort by:
rhodotorulic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity 		ISO Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
S-methyl-L-thiocitrulline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 multiple interactions EXP S-methylthiocitrulline inhibits the reaction [EDN1 protein results in increased abundance of Nitric Oxide] CTD PMID:16380457 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
decreases activity 		EXP
ISO 		[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the abundance of Sodium
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine 		CTD PMID:11006970 PMID:12511180 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] CTD PMID:17683483 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231 		JBrowse link
sinefungin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 decreases activity ISO sinefungin results in decreased activity of DNMT1 protein CTD PMID:23671287 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases activity ISO sinefungin results in decreased activity of DNMT3A protein CTD PMID:23671287 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        pharmaceutical 20416
          drug 20416
            protective agent 18636
              hepatoprotective agent 5920
                L-ornithine 6
                  L-Orn-D-Asp 0
                  L-Orn-D-Glu 0
                  L-ornithine derivative + 4
                  L-ornithine residue + 0
                  L-ornithine-d6 0
                  L-ornithyl group 0
                  N(2)-L-ornithino group 0
                  N(5)-L-ornithino group 0
                  sinefungin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20574
                        hydrogen molecular entity 20558
                          hydrides 19693
                            inorganic hydride 18602
                              pnictogen hydride 18589
                                nitrogen hydride 18502
                                  azane 18262
                                    ammonia 18261
                                      organic amino compound 18261
                                        amino acid 16340
                                          alpha-amino acid 14255
                                            non-proteinogenic alpha-amino acid 3854
                                              ornithine 12
                                                L-ornithine 6
                                                  L-Orn-D-Asp 0
                                                  L-Orn-D-Glu 0
                                                  L-ornithine derivative + 4
                                                  L-ornithine residue + 0
                                                  L-ornithine-d6 0
                                                  L-ornithyl group 0
                                                  N(2)-L-ornithino group 0
                                                  N(5)-L-ornithino group 0
                                                  sinefungin 2
paths to the root