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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(N(omega)-L-arginino)succinic acid
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Accession:CHEBI:15682 term browser browse the term
Definition:A L-arginine derivative that has formula C10H18N4O6.
Synonyms:exact_synonym: 2-(N(omega)-L-arginino)butanedioic acid
 related_synonym: 2-(Nomega-L-Arginino)succinate;   Formula=C10H18N4O6;   InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1;   InChIKey=KDZOASGQNOPSCU-ZBHICJROSA-N;   L-Argininosuccinate;   L-Argininosuccinic acid;   L-Arginosuccinic acid;   N(omega)-(L-Arginino)succinate;   N-(L-Arginino)succinate;   SMILES=N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O
 alt_id: CHEBI:10960;   CHEBI:21475;   CHEBI:7098
 xref: CAS:2387-71-5;   KEGG:C03406;   KNApSAcK:C00019688
 xref_mesh: MESH:D001125
 cyclic_relationship: is_conjugate_acid_of CHEBI:57472


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(N(omega)-L-arginino)succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
decreases abundance 		ISO Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid] CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      application 20617
        indicator 8819
          biomarker 6604
            L-arginine 125
              L-arginine derivative 101
                (N(omega)-L-arginino)succinic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    main group molecular entity 20777
                      s-block molecular entity 20573
                        hydrogen molecular entity 20557
                          hydrides 19691
                            inorganic hydride 18601
                              pnictogen hydride 18587
                                nitrogen hydride 18502
                                  azane 18261
                                    ammonia 18260
                                      organic amino compound 18260
                                        amino acid 16329
                                          alpha-amino acid 14212
                                            L-alpha-amino acid 12357
                                              glutamine family amino acid 10351
                                                L-arginine 125
                                                  L-arginine derivative 101
                                                    (N(omega)-L-arginino)succinic acid 2
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