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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(N(omega)-L-arginino)succinic acid
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Accession:CHEBI:15682 term browser browse the term
Definition:A L-arginine derivative that has formula C10H18N4O6.
Synonyms:exact_synonym: 2-(N(omega)-L-arginino)butanedioic acid
 related_synonym: 2-(Nomega-L-Arginino)succinate;   Formula=C10H18N4O6;   InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1;   InChIKey=KDZOASGQNOPSCU-ZBHICJROSA-N;   L-Argininosuccinate;   L-Argininosuccinic acid;   L-Arginosuccinic acid;   N(omega)-(L-Arginino)succinate;   N-(L-Arginino)succinate;   SMILES=N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O
 alt_id: CHEBI:10960;   CHEBI:21475;   CHEBI:7098
 xref: CAS:2387-71-5;   KEGG:C03406;   KNApSAcK:C00019688
 xref_mesh: MESH:D001125
 cyclic_relationship: is_conjugate_acid_of CHEBI:57472


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(N(omega)-L-arginino)succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
decreases abundance		 ISO Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        indicator 8780
          biomarker 6586
            L-arginine 106
              L-arginine derivative 92
                (N(omega)-L-arginino)succinic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      s-block molecular entity 19681
                        hydrogen molecular entity 19662
                          hydrides 19167
                            inorganic hydride 18182
                              pnictogen hydride 18172
                                nitrogen hydride 18085
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17888
                                        amino acid 16071
                                          alpha-amino acid 13929
                                            L-alpha-amino acid 12971
                                              glutamine family amino acid 10316
                                                L-arginine 106
                                                  L-arginine derivative 92
                                                    (N(omega)-L-arginino)succinic acid 2
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