CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: (+)-albicanol
Accession: CHEBI:155904
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Definition: A drimane-type sesquiterpenoid orginally isolated from the liverwort Diplophyllum albicans. It exhibits fish antifeedant, antifungal and antineoplastic activities.
Synonyms: exact_synonym: [(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]methanol
related_synonym: (1S,4aalpha)-decahydro-5,5,8abeta-trimethyl-2-methylenenaphthalene-1-methanol; (4aalpha)-2-methylene-5,5,8abeta-trimethyldecalin-1beta-methanol; (4aalpha)-decahydro-5,5,8abeta-trimethyl-2-methylenenaphthalene-1beta-methanol; (8aS)-albicanol; Formula=C15H26O; InChI=1S/C15H26O/c1-11-6-7-13-14(2,3)8-5-9-15(13,4)12(11)10-16/h12-13,16H,1,5-10H2,2-4H3/t12-,13-,15+/m0/s1; InChIKey=ZPTSRWNMMWXEHX-KCQAQPDRSA-N; SMILES=[C@@H]1(C(CC[C@]2(C(CCC[C@]12C)(C)C)[H])=C)CO
xref: CAS:54632-04-1; KNApSAcK:C00020283
xref_mesh: MESH:C438910
xref: PMCID:PMC7278516; PMID:10959585; PMID:11440150; PMID:12130851; PMID:12350155; PMID:16913486; PMID:18310958; PMID:19594165; PMID:19801866; PMID:22660771; PMID:24647035; PMID:32548177
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Casp3
caspase 3
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in increased expression of CASP3 mRNA]
CTD
PMID:33761044
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in increased expression of CASP9 mRNA]
CTD
PMID:33761044
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in decreased activity of CAT protein]
CTD
PMID:33761044
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Hmox1
heme oxygenase 1
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in decreased expression of HMOX1 protein]
CTD
PMID:33761044
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Il1b
interleukin 1 beta
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in increased expression of IL1B mRNA]
CTD
PMID:33761044
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Keap1
Kelch-like ECH-associated protein 1
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA]; albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein]
CTD
PMID:33761044
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 protein]
CTD
PMID:33761044
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in decreased expression of NQO1 protein]
CTD
PMID:33761044
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Sod2
superoxide dismutase 2
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in decreased expression of SOD2 protein]
CTD
PMID:33761044
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Tnf
tumor necrosis factor
multiple interactions
ISO
albicanol inhibits the reaction [Galactose results in increased expression of TNF mRNA]
CTD
PMID:33761044
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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